Charles Jason Frazier, Ph.D. - Publications

Affiliations: 
Pharmacodynamics University of Florida, Gainesville, Gainesville, FL, United States 

51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Baumer-Harrison C, Elsaafien K, Johnson DN, Aponte JDP, de Araujo A, Patel S, Bruce E, Harden SW, Frazier CJ, Scott KA, de Lartigue G, Krause EG, de Kloet AD. Alleviating hypertension by selectively targeting angiotensin receptor expressing vagal sensory neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 38242697 DOI: 10.1523/JNEUROSCI.1154-23.2023  0.717
2023 Truckenbrod LM, Betzhold SM, Wheeler AR, Shallcross J, Singhal S, Harden S, Schwendt M, Frazier CJ, Bizon JL, Setlow B, Orsini CA. Circuit and cell-specific contributions to decision making involving risk of explicit punishment in male and female rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 37286352 DOI: 10.1523/JNEUROSCI.0276-23.2023  0.784
2023 Truckenbrod LM, Betzhold SM, Wheeler AR, Shallcross J, Singhal S, Harden S, Schwendt M, Frazier CJ, Bizon JL, Setlow B, Orsini CA. Circuit and cell-specific contributions to decision making involving risk of explicit punishment in male and female rats. Biorxiv : the Preprint Server For Biology. PMID 36711946 DOI: 10.1101/2023.01.15.524142  0.788
2022 Thinschmidt JS, Harden SW, King MA, Talton JD, Frazier CJ. A rapid assay for evaluating the effects of acetylcholinesterase inhibitors and reactivators in the rat basolateral amygdala. Frontiers in Cellular Neuroscience. 16: 1066312. PMID 36479275 DOI: 10.3389/fncel.2022.1066312  0.714
2022 Elsaafien K, Harden SW, Johnson DN, Kimball AK, Sheng W, Smith JA, Scott KA, Frazier CJ, de Kloet AD, Krause EG. A Novel Organ-Specific Approach to Selectively Target Sensory Afferents Innervating the Aortic Arch. Frontiers in Physiology. 13: 841078. PMID 35399269 DOI: 10.3389/fphys.2022.841078  0.766
2021 McQuail JA, Beas BS, Kelly KB, Hernandez CM, Bizon JL, Frazier CJ. Attenuated NMDAR signaling on fast-spiking interneurons in prefrontal cortex contributes to age-related decline of cognitive flexibility. Neuropharmacology. 108720. PMID 34273386 DOI: 10.1016/j.neuropharm.2021.108720  0.662
2021 Sheng W, Harden SW, Tan Y, Krause EG, Frazier CJ. Dendritic osmosensors modulate activity-induced calcium influx in oxytocinergic magnocellular neurons of the mouse PVN. Elife. 10. PMID 34250900 DOI: 10.7554/eLife.63486  0.774
2021 Liu Y, Xing H, Sheng W, Singh KN, Korkmaz AG, Comeau C, Anika M, Ernst A, Yokoi F, Vaillancourt DE, Frazier CJ, Li Y. Alteration of the cholinergic system and motor deficits in cholinergic neuron-specific Dyt1 knockout mice. Neurobiology of Disease. 105342. PMID 33757902 DOI: 10.1016/j.nbd.2021.105342  0.572
2021 Mohammed M, Johnson DN, Wang LA, Harden SW, Sheng W, Spector EA, Elsaafien K, Bader M, Steckelings UM, Scott KA, Frazier CJ, Sumners C, Krause EG, de Kloet AD. Targeting angiotensin type 2 receptors located on pressor neurons in the nucleus of the solitary tract to relieve hypertension in mice. Cardiovascular Research. PMID 33723600 DOI: 10.1093/cvr/cvab085  0.786
2020 Frazier CJ, Harden SW, Alleyne AR, Mohammed M, Sheng W, Smith JA, Elsaafien K, Spector EA, Johnson DN, Scott KA, Krause EG, de Kloet AD. An Angiotensin-responsive Connection from the Lamina Terminalis to the Paraventricular Nucleus of the Hypothalamus Evokes Vasopressin Secretion to Increase Blood Pressure in Mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33328294 DOI: 10.1523/JNEUROSCI.1600-20.2020  0.79
2020 Pati D, Harden SW, Sheng W, Kelly KB, de Kloet AD, Krause EG, Frazier CJ. Endogenous oxytocin inhibits hypothalamic corticotrophin-releasing hormone neurones following acute hypernatraemia. Journal of Neuroendocrinology. e12839. PMID 32133707 DOI: 10.1111/Jne.12839  0.797
2020 Cirino TJ, Harden SW, McLaughlin JP, Frazier CJ. Region-specific effects of HIV-1 Tat on intrinsic electrophysiological properties of pyramidal neurons in mouse prefrontal cortex and hippocampus. Journal of Neurophysiology. PMID 32101482 DOI: 10.1152/Jn.00029.2020  0.71
2020 Mohammed M, Sumners C, Sheng W, Harden SW, Frazier CJ, Johnson D, Scott KA, Krause EG, de Kloet AD. Angiotensin AT2 receptors in the solitary tract nucleus lower blood pressure via inhibition of GABA signaling The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.06415  0.769
2019 Hernandez CM, Orsini CA, Labiste CC, Wheeler AR, Ten Eyck TW, Bruner MM, Sahagian TJ, Harden SW, Frazier CJ, Setlow B, Bizon JL. Optogenetic dissection of basolateral amygdala contributions to intertemporal choice in young and aged rats. Elife. 8. PMID 31017572 DOI: 10.7554/Elife.46174  0.756
2019 Tan Y, Singhal SM, Harden SW, Cahill KM, Nguyen DM, Colon-Perez LM, Sahagian TJ, Thinschmidt JS, de Kloet AD, Febo M, Frazier CJ, Krause EG. Oxytocin receptors are expressed by glutamatergic prefrontal cortical neurons that selectively modulate social recognition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30804095 DOI: 10.1523/Jneurosci.2944-18.2019  0.754
2019 Hernandez CM, Orsini CA, Labiste CC, Wheeler A, Eyck TWT, Bruner MM, Sahagian TJ, Harden SW, Frazier CJ, Setlow B, Bizon JL. Author response: Optogenetic dissection of basolateral amygdala contributions to intertemporal choice in young and aged rats Elife. DOI: 10.7554/Elife.46174.024  0.749
2017 Orsini CA, Hernandez CM, Singhal S, Kelly KB, Frazier CJ, Bizon JL, Setlow B. Optogenetic inhibition reveals distinct roles for basolateral amygdala activity at discrete timepoints during risky decision making. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29079687 DOI: 10.1523/Jneurosci.2344-17.2017  0.77
2017 Krause EG, Pati D, Frazier CJ. Chronic salt-loading reduces basal excitatory input to CRH neurons in the paraventricular nucleus and accelerates recovery from restraint stress in male mice. Physiology & Behavior. PMID 28351560 DOI: 10.1016/J.Physbeh.2017.03.038  0.726
2017 Tan Y, Singhal S, Hiller H, Nguyen D, Colon-Perez LM, Febo M, Wang L, Kloet ADd, Frazier CJ, Krause EG. Oxytocin Receptors are expressed on Neurons within the Prefrontal Cortex that Control Preference for Social Novelty The Faseb Journal. 31. DOI: 10.1096/Fasebj.31.1_Supplement.1076.13  0.789
2016 McQuail JA, Beas BS, Kelly KB, Simpson KL, Frazier CJ, Setlow B, Bizon JL. NR2A-containing NMDARs in the prefrontal cortex are required for working memory and associated with age-related cognitive decline. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 27807032 DOI: 10.1523/Jneurosci.2332-16.2016  0.65
2016 Carpenter HE, Kelly KB, Bizon JL, Frazier CJ. Age-related changes in tonic activation of presynaptic versus extrasynaptic γ-amniobutyric acid type B receptors in rat medial prefrontal cortex. Neurobiology of Aging. 45: 88-97. PMID 27459929 DOI: 10.1016/J.Neurobiolaging.2016.05.015  0.709
2016 Pati D, Kelly K, Stennett B, Frazier CJ, Knackstedt LA. Alcohol consumption increases basal extracellular glutamate in the nucleus accumbens core of Sprague-Dawley rats without increasing spontaneous glutamate release. The European Journal of Neuroscience. PMID 27207718 DOI: 10.1111/Ejn.13284  0.774
2016 Harden SW, Frazier CJ. Oxytocin Depolarizes Fast-Spiking Hilar Interneurons and Induces GABA Release onto Mossy Cells of the Rat Dentate Gyrus. Hippocampus. PMID 27068005 DOI: 10.1002/Hipo.22595  0.747
2016 Wang L, de Kloet AD, Pati D, Hiller H, Smith JA, Pioquinto DJ, Ludin JA, Oh SP, Katovich MJ, Frazier CJ, Rsaizada MK, Krause EG. Increasing brain angiotensin converting enzyme 2 activity decreases anxiety-like behavior in male mice by activating central Mas receptors. Neuropharmacology. PMID 26767952 DOI: 10.1016/J.Neuropharm.2015.12.026  0.739
2016 Carpenter HE, Kelly KB, Bizon JL, Frazier CJ. Age-related changes in tonic activation of presynaptic versus extrasynaptic γ-amniobutyric acid type B receptors in rat medial prefrontal cortex Neurobiology of Aging. 45: 88-97. DOI: 10.1016/j.neurobiolaging.2016.05.015  0.684
2015 McQuail JA, Frazier CJ, Bizon JL. Molecular aspects of age-related cognitive decline: the role of GABA signaling. Trends in Molecular Medicine. 21: 450-60. PMID 26070271 DOI: 10.1016/J.Molmed.2015.05.002  0.363
2015 Smith JA, Pati D, Wang L, de Kloet AD, Frazier CJ, Krause EG. Hydration and beyond: neuropeptides as mediators of hydromineral balance, anxiety and stress-responsiveness. Frontiers in Systems Neuroscience. 9: 46. PMID 25873866 DOI: 10.3389/Fnsys.2015.00046  0.718
2014 Graves CL, Harden SW, LaPato M, Nelson M, Amador B, Sorenson H, Frazier CJ, Wallet SM. A method for high purity intestinal epithelial cell culture from adult human and murine tissues for the investigation of innate immune function. Journal of Immunological Methods. 414: 20-31. PMID 25193428 DOI: 10.1016/J.Jim.2014.08.002  0.669
2013 Frazier CJ. Preformed vs. on-demand: molecular economics of endocannabinoid signalling. The Journal of Physiology. 591: 4683-4. PMID 24085490 DOI: 10.1113/Jphysiol.2013.262717  0.416
2013 Frazier CJ, Pati D, Hiller H, Nguyen D, Wang L, Smith JA, MacFadyen K, de Kloet AD, Krause EG. Acute hypernatremia exerts an inhibitory oxytocinergic tone that is associated with anxiolytic mood in male rats. Endocrinology. 154: 2457-67. PMID 23653461 DOI: 10.1210/En.2013-1049  0.729
2013 de Kloet AD, Pati D, Wang L, Hiller H, Sumners C, Frazier CJ, Seeley RJ, Herman JP, Woods SC, Krause EG. Angiotensin type 1a receptors in the paraventricular nucleus of the hypothalamus protect against diet-induced obesity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 4825-33. PMID 23486953 DOI: 10.1523/Jneurosci.3806-12.2013  0.716
2013 Hofmann ME, Frazier CJ. Marijuana, endocannabinoids, and epilepsy: potential and challenges for improved therapeutic intervention. Experimental Neurology. 244: 43-50. PMID 22178327 DOI: 10.1016/J.Expneurol.2011.11.047  0.744
2012 Kagan Z, Frazier CJ, Talathi SS. STDP induced synchrony in inhibitory neural networks: theory and experiments Bmc Neuroscience. 13: P32. DOI: 10.1186/1471-2202-13-S1-P32  0.387
2011 Frazier CJ. Key questions of endocannabinoid signalling in the CNS: which, where and when? The Journal of Physiology. 589: 4807-8. PMID 22001725 DOI: 10.1113/Jphysiol.2011.219493  0.39
2011 Hofmann ME, Bhatia C, Frazier CJ. Cannabinoid receptor agonists potentiate action potential-independent release of GABA in the dentate gyrus through a CB1 receptor-independent mechanism. The Journal of Physiology. 589: 3801-21. PMID 21646412 DOI: 10.1113/Jphysiol.2011.211482  0.81
2010 Lindsly C, Frazier CJ. Two distinct and activity-dependent mechanisms contribute to autoreceptor-mediated inhibition of GABAergic afferents to hilar mossy cells. The Journal of Physiology. 588: 2801-22. PMID 20547680 DOI: 10.1113/Jphysiol.2009.184648  0.412
2010 Hofmann ME, Frazier CJ. Muscarinic receptor activation modulates the excitability of hilar mossy cells through the induction of an afterdepolarization. Brain Research. 1318: 42-51. PMID 20079344 DOI: 10.1016/J.Brainres.2010.01.011  0.793
2010 Nahir B, Lindsly C, Frazier CJ. mGluR-mediated and endocannabinoid-dependent long-term depression in the hilar region of the rat dentate gyrus. Neuropharmacology. 58: 712-21. PMID 20045707 DOI: 10.1016/J.Neuropharm.2009.12.022  0.796
2008 Hofmann ME, Nahir B, Frazier CJ. Excitatory afferents to CA3 pyramidal cells display differential sensitivity to CB1 dependent inhibition of synaptic transmission. Neuropharmacology. 55: 1140-6. PMID 18675282 DOI: 10.1016/J.Neuropharm.2008.07.007  0.781
2007 Nahir B, Bhatia C, Frazier CJ. Presynaptic inhibition of excitatory afferents to hilar mossy cells. Journal of Neurophysiology. 97: 4036-47. PMID 17442771 DOI: 10.1152/Jn.00069.2007  0.781
2006 Hofmann ME, Nahir B, Frazier CJ. Endocannabinoid-mediated depolarization-induced suppression of inhibition in hilar mossy cells of the rat dentate gyrus. Journal of Neurophysiology. 96: 2501-12. PMID 16807350 DOI: 10.1152/Jn.00310.2006  0.798
2005 Thinschmidt JS, Frazier CJ, King MA, Meyer EM, Papke RL. Medial septal/diagonal band cells express multiple functional nicotinic receptor subtypes that are correlated with firing frequency. Neuroscience Letters. 389: 163-8. PMID 16112453 DOI: 10.1016/J.Neulet.2005.07.038  0.624
2005 Thinschmidt JS, Frazier CJ, King MA, Meyer EM, Papke RL. Septal innervation regulates the function of alpha7 nicotinic receptors in CA1 hippocampal interneurons. Experimental Neurology. 195: 342-52. PMID 16000197 DOI: 10.1016/J.Expneurol.2005.05.006  0.588
2003 Frazier CJ, Strowbridge BW, Papke RL. Nicotinic receptors on local circuit neurons in dentate gyrus: a potential role in regulation of granule cell excitability. Journal of Neurophysiology. 89: 3018-28. PMID 12611982 DOI: 10.1152/Jn.01036.2002  0.657
2001 Frazier CJ, Serrano JR, George EG, Yu X, Viswanathan A, Perez-Reyes E, Jones SW. Gating kinetics of the alpha1I T-type calcium channel. The Journal of General Physiology. 118: 457-70. PMID 11696605 DOI: 10.1085/Jgp.118.5.457  0.402
2000 Frazier CJ, George EG, Jones SW. Apparent change in ion selectivity caused by changes in intracellular K(+) during whole-cell recording. Biophysical Journal. 78: 1872-80. PMID 10733967 DOI: 10.1016/S0006-3495(00)76736-1  0.378
1998 Frazier CJ, Buhler AV, Weiner JL, Dunwiddie TV. Synaptic potentials mediated via alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors in rat hippocampal interneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 8228-35. PMID 9763468 DOI: 10.1523/Jneurosci.18-20-08228.1998  0.615
1998 Frazier CJ, Rollins YD, Breese CR, Leonard S, Freedman R, Dunwiddie TV. Acetylcholine activates an alpha-bungarotoxin-sensitive nicotinic current in rat hippocampal interneurons, but not pyramidal cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 1187-95. PMID 9454829  0.597
1998 Frazier CJ, Rollins YD, Breese CR, Leonard S, Freedman R, Dunwiddie TV. Acetylcholine Activates an α-Bungarotoxin-Sensitive Nicotinic Current in Rat Hippocampal Interneurons, But Not Pyramidal Cells The Journal of Neuroscience. 18: 1187-1195. DOI: 10.1523/Jneurosci.18-04-01187.1998  0.421
1997 Weiner JL, Valenzuela CF, Watson PL, Frazier CJ, Dunwiddie TV. Elevation of basal protein kinase C activity increases ethanol sensitivity of GABA(A) receptors in rat hippocampal CA1 pyramidal neurons. Journal of Neurochemistry. 68: 1949-59. PMID 9109521 DOI: 10.1046/J.1471-4159.1997.68051949.X  0.673
1996 Valenzuela CF, Xiong Z, MacDonald JF, Weiner JL, Frazier CJ, Dunwiddie TV, Kazlauskas A, Whiting PJ, Harris RA. Platelet-derived growth factor induces a long-term inhibition of N-methyl-D-aspartate receptor function. The Journal of Biological Chemistry. 271: 16151-9. PMID 8663218 DOI: 10.1074/Jbc.271.27.16151  0.665
Show low-probability matches.