James Mele, Ph.D.

2003 The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States 
Molecular Biology, Immunology
"James Mele"


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Arlan Richardson grad student 2003 UT Health San Antonio
 (Characterization of transgenic mice that overexpress the superoxide dismutases and catalase: An examination of the interactions in the antioxidant defense system.)
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Mele J, Maloyan A, Myatt L. (2013) Metabolic response of syncytiotrophoblast mitochondria to maternal obesity Placenta. 34: A38
Lewis KN, Mele J, Hornsby PJ, et al. (2012) Stress resistance in the naked mole-rat: the bare essentials - a mini-review. Gerontology. 58: 453-62
Maloyan A, Mele J, Muralimanohara B, et al. (2012) Measurement of mitochondrial respiration in trophoblast culture Placenta. 33: 456-458
Edrey YH, Casper D, Huchon D, et al. (2012) Sustained high levels of neuregulin-1 in the longest-lived rodents; a key determinant of rodent longevity. Aging Cell. 11: 213-22
Edrey YH, Hanes M, Pinto M, et al. (2011) Successful aging and sustained good health in the naked mole rat: a long-lived mammalian model for biogerontology and biomedical research. Ilar Journal. 52: 41-53
Lewis KN, Mele J, Hayes JD, et al. (2010) Nrf2, a guardian of healthspan and gatekeeper of species longevity. Integrative and Comparative Biology. 50: 829-43
Mele J, Edrey YH, Lewis KN, et al. (2010) Mechanisms of aging in the naked mole-rat: The case for programmed aging Russian Journal of General Chemistry. 80: 1455-1464
Jang YC, Pérez VI, Song W, et al. (2009) Overexpression of Mn superoxide dismutase does not increase life span in mice. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 64: 1114-25
Pérez VI, Bokov A, Van Remmen H, et al. (2009) Is the oxidative stress theory of aging dead? Biochimica Et Biophysica Acta. 1790: 1005-14
Pérez VI, Buffenstein R, Masamsetti V, et al. (2009) Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat. Proceedings of the National Academy of Sciences of the United States of America. 106: 3059-64
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