Florian L. Muller, Ph.D.

Affiliations: 
2007 The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States 
Area:
Biochemistry, Molecular Biology, Neuroscience Biology
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"Florian Muller"
Cross-listing: Imaging Tree

Parents

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Arlan Richardson grad student 2007 UT Health San Antonio
 (On the role of superoxide in amyotrophic lateral sclerosis.)
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Publications

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Jang YC, Rodriguez K, Lustgarten MS, et al. (2020) Superoxide-mediated oxidative stress accelerates skeletal muscle atrophy by synchronous activation of proteolytic systems. Geroscience
Sun Y, Bandi M, Lofton T, et al. (2019) Functional Genomics Reveals Synthetic Lethality between Phosphogluconate Dehydrogenase and Oxidative Phosphorylation. Cell Reports. 26: 469-482.e5
Muller F, Hammoudi N, Lin Y, et al. (2019) YIA19-004: Collateral Deletion of Glycolysis Genes Generates Selective Vulnerabilities to Inhibitors of Oxidative Phosphorylation Journal of the National Comprehensive Cancer Network. 17
Molina JR, Sun Y, Protopopova M, et al. (2018) An inhibitor of oxidative phosphorylation exploits cancer vulnerability. Nature Medicine
Lissanu Deribe Y, Sun Y, Terranova C, et al. (2018) Mutations in the SWI/SNF complex induce a targetable dependence on oxidative phosphorylation in lung cancer. Nature Medicine
Dey P, Baddour J, Kim Y, et al. (2018) Abstract 777: Malic enzyme 3 as a collateral lethality target in pancreatic cancer Cancer Research. 78: 777-777
Francesco MED, Marszalek JR, McAfoos T, et al. (2018) Abstract 1655: Discovery and development of IACS-010759, a novel inhibitor of Complex I currently in phase I studies to exploit oxidative phosphorylation dependency in acute myeloid leukemia and solid tumors Cancer Research. 78: 1655-1655
Hwang I, Oh H, Santo E, et al. (2017) FOXO protects against age-progressive axonal degeneration. Aging Cell
Genovese G, Carugo A, Tepper J, et al. (2017) Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer. Nature
Dey P, Baddour J, Muller F, et al. (2017) Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer. Nature
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