Michael A. Holinstat
Affiliations: | University of Michigan, Ann Arbor, Ann Arbor, MI |
Area:
Pharmacology, cardiovascular, thrombosis, human, mice, plateletsGoogle:
"Michael Holinstat"Parents
Sign in to add mentor| Asrar B. Malik | grad student | 2000-2004 | University of Illinois at Chicago, Health Sciences Center | |
| (RhoA regulation of endothelial monolayer integrity.) | ||||
| Heidi E. Hamm | post-doc | 2004-2008 | Vanderbilt University Medical School (Chemistry Tree) | |
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Publications
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| Poscablo DM, Worthington AK, Smith-Berdan S, et al. (2024) An age-progressive platelet differentiation path from hematopoietic stem cells causes exacerbated thrombosis. Cell |
| Stanger L, Yamaguchi A, Holinstat M. (2023) Antiplatelet strategies: past, present, and future. Journal of Thrombosis and Haemostasis : Jth. 21: 3317-3328 |
| Kulkarni PP, Alluri RK, Godwin M, et al. (2023) Protection of β2GPI Deficient Mice from Thrombosis Reflects a Defect in PAR3-facilitated Platelet Activation. Biorxiv : the Preprint Server For Biology |
| Larsen HJ, Byrne D, Özpolat T, et al. (2023) Loss of 12-Lipoxygenase Improves the Post-Transfusion Function of Stored Platelets. Arteriosclerosis, Thrombosis, and Vascular Biology |
| Stanger L, Yamaguchi A, Yalavarthi P, et al. (2023) The oxylipin analogue CS585 prevents platelet activation and thrombosis through activation of the prostacyclin receptor. Blood |
| Mobbs JI, Black KA, Tran M, et al. (2023) Cryo-EM structures of human arachidonate 12S-Lipoxygenase (12-LOX) bound to endogenous and exogenous inhibitors. Blood |
| Renna SA, Zhao X, Kunapuli SP, et al. (2023) Novel Strategy to Combat the Procoagulant Phenotype in Heparin-Induced Thrombocytopenia Using 12-LOX Inhibition. Arteriosclerosis, Thrombosis, and Vascular Biology |
| Banka AL, Guevara MV, Brannon ER, et al. (2023) Cargo-free particles divert neutrophil-platelet aggregates to reduce thromboinflammation. Nature Communications. 14: 2462 |
| Stanger L, Holinstat M. (2023) Bioactive lipid regulation of platelet function, hemostasis, and thrombosis. Pharmacology & Therapeutics. 246: 108420 |
| Yamaguchi A, van Hoorebeke C, Tourdot BE, et al. (2023) Fatty acids negatively regulate platelet function through formation of noncanonical 15-lipoxygenase-derived eicosanoids. Pharmacology Research & Perspectives. 11: e01056 |