Frances M. Ashcroft
Affiliations: | University of Oxford, Oxford, United Kingdom |
Area:
ion channelsGoogle:
"Frances Ashcroft"Cross-listing: Neurotree
Children
Sign in to add trainee| Denis Burdakov | grad student | Oxford (Neurotree) | |
| Fiona M. Gribble | grad student | Oxford | |
| Jochen Roeper | post-doc | Oxford (Neurotree) | |
| Stephen J. Tucker | post-doc | (Neurotree) |
Collaborators
Sign in to add collaborator| Paul Smith | collaborator | University of East Anglia (STSTree) |
BETA: Related publications
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Publications
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| Sachse G, Haythorne E, Hill T, et al. (2021) The KCNJ11-E23K Gene Variant Hastens Diabetes Progression by Impairing Glucose-Induced Insulin Secretion. Diabetes |
| Sachse G, Haythorne E, Proks P, et al. (2020) Phenotype of a transient neonatal diabetes point mutation (SUR1-R1183W) in mice. Wellcome Open Research. 5: 15 |
| Pipatpolkai T, Usher S, Stansfeld PJ, et al. (2020) New insights into K channel gene mutations and neonatal diabetes mellitus. Nature Reviews. Endocrinology |
| Usher SG, Ashcroft FM, Puljung MC. (2020) Nucleotide inhibition of the pancreatic ATP-sensitive K channel explored with patch-clamp fluorometry. Elife. 9 |
| Haythorne E, Rohm M, van de Bunt M, et al. (2019) Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells. Nature Communications. 10: 2474 |
| Vergari E, Knudsen JG, Ramracheya R, et al. (2019) Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion. Nature Communications. 10: 139 |
| Knudsen JG, Hamilton A, Ramracheya R, et al. (2018) Dysregulation of Glucagon Secretion by Hyperglycemia-Induced Sodium-Dependent Reduction of ATP Production. Cell Metabolism |
| Vedovato N, Rorsman O, Hennis K, et al. (2018) Role of the C-terminus of SUR in the differential regulation of β-cell and cardiac K channels by MgADP and metabolism. The Journal of Physiology |
| Misra S, Vedovato N, Cliff E, et al. (2018) Permanent neonatal diabetes: combining sulfonylureas with insulin may be an effective treatment. Diabetic Medicine : a Journal of the British Diabetic Association |
| Proks P, Kramer H, Haythorne E, et al. (2018) Binding of sulphonylureas to plasma proteins - A KATP channel perspective. Plos One. 13: e0197634 |