Frances M. Ashcroft

University of Oxford, Oxford, United Kingdom 
ion channels
"Frances Ashcroft"
Cross-listing: Neurotree


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Denis Burdakov grad student Oxford (Neurotree)
Fiona M. Gribble grad student Oxford
Jochen Roeper post-doc Oxford (Neurotree)
Stephen J. Tucker post-doc (Neurotree)
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Sachse G, Haythorne E, Hill T, et al. (2021) The KCNJ11-E23K Gene Variant Hastens Diabetes Progression by Impairing Glucose-Induced Insulin Secretion. Diabetes
Sachse G, Haythorne E, Proks P, et al. (2020) Phenotype of a transient neonatal diabetes point mutation (SUR1-R1183W) in mice. Wellcome Open Research. 5: 15
Pipatpolkai T, Usher S, Stansfeld PJ, et al. (2020) New insights into K channel gene mutations and neonatal diabetes mellitus. Nature Reviews. Endocrinology
Usher SG, Ashcroft FM, Puljung MC. (2020) Nucleotide inhibition of the pancreatic ATP-sensitive K channel explored with patch-clamp fluorometry. Elife. 9
Haythorne E, Rohm M, van de Bunt M, et al. (2019) Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells. Nature Communications. 10: 2474
Vergari E, Knudsen JG, Ramracheya R, et al. (2019) Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion. Nature Communications. 10: 139
Knudsen JG, Hamilton A, Ramracheya R, et al. (2018) Dysregulation of Glucagon Secretion by Hyperglycemia-Induced Sodium-Dependent Reduction of ATP Production. Cell Metabolism
Vedovato N, Rorsman O, Hennis K, et al. (2018) Role of the C-terminus of SUR in the differential regulation of β-cell and cardiac K channels by MgADP and metabolism. The Journal of Physiology
Misra S, Vedovato N, Cliff E, et al. (2018) Permanent neonatal diabetes: combining sulfonylureas with insulin may be an effective treatment. Diabetic Medicine : a Journal of the British Diabetic Association
Proks P, Kramer H, Haythorne E, et al. (2018) Binding of sulphonylureas to plasma proteins - A KATP channel perspective. Plos One. 13: e0197634
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