Nazzareno D'Avanzo, PhD

2012- Pharmacologie et Physiologie Université de Montréal, Montréal, Canada 
Biophysics, ion channels, lipids,
"Nazzareno D'Avanzo"


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Peter H. Backx grad student 2003-2007 University of Toronto (Cell Biology Tree)
Declan A. Doyle post-doc 2007-2009 (Neurotree)
Colin G. Nichols post-doc 2009-2012 (Neurotree)


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Karen M. Callahan research assistant 2014- Université de Montréal (Chemistry Tree)
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Callahan KM, Mondou B, Sasseville L, et al. (2019) The influence of membrane bilayer thickness on KcsA channel activity. Channels (Austin, Tex.). 13: 424-439
Tanguay J, Callahan KM, D'Avanzo N. (2019) Characterization of drug binding within the HCN1 channel pore. Scientific Reports. 9: 465
Fürst O, Nichols CG, Lamoureux G, et al. (2014) Identification of a cholesterol-binding pocket in inward rectifier K(+) (Kir) channels. Biophysical Journal. 107: 2786-96
Fürst O, Mondou B, D'Avanzo N. (2014) Phosphoinositide regulation of inward rectifier potassium (Kir) channels. Frontiers in Physiology. 4: 404
D'Avanzo N, McCusker EC, Powl AM, et al. (2013) Differential lipid dependence of the function of bacterial sodium channels. Plos One. 8: e61216
D'Avanzo N, Lee SJ, Cheng WW, et al. (2013) Energetics and location of phosphoinositide binding in human Kir2.1 channels. The Journal of Biological Chemistry. 288: 16726-37
McCusker EC, Bagnéris C, Naylor CE, et al. (2012) Structure of a bacterial voltage-gated sodium channel pore reveals mechanisms of opening and closing. Nature Communications. 3: 1102
D'Avanzo N, Hyrc K, Enkvetchakul D, et al. (2011) Enantioselective protein-sterol interactions mediate regulation of both prokaryotic and eukaryotic inward rectifier K+ channels by cholesterol. Plos One. 6: e19393
McCusker EC, D'Avanzo N, Nichols CG, et al. (2011) Simplified bacterial "pore" channel provides insight into the assembly, stability, and structure of sodium channels. The Journal of Biological Chemistry. 286: 16386-91
Cheng WW, D'Avanzo N, Doyle DA, et al. (2011) Dual-mode phospholipid regulation of human inward rectifying potassium channels. Biophysical Journal. 100: 620-8
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