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Schade M, Scott JS, Hayhow TG, et al. (2024) Structural and Physicochemical Features of Oral PROTACs. Journal of Medicinal Chemistry |
Grimster NP, Gingipalli L, Balazs A, et al. (2023) Optimization of a Series of Novel, Potent and Selective Macrocyclic SYK Inhibitors. Bioorganic & Medicinal Chemistry Letters. 129352 |
Beaumont K, Pike A, Davies M, et al. (2022) ADME and DMPK considerations for the Discovery and Development of Antibody Drug Conjugates (ADCs). Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 1-44 |
Srivastava A, Pike A, Williamson B, et al. (2020) A novel method for preventing non-specific binding in equilibrium dialysis assays using Solutol® as an additive. Journal of Pharmaceutical Sciences |
Barlaam B, Boiko S, Boyd S, et al. (2020) Novel potent and selective pyrazolylpyrimidine-based SYK inhibitors. Bioorganic & Medicinal Chemistry Letters. 127523 |
Pike A, Williamson B, Harlfinger S, et al. (2020) Optimising proteolysis-targeting chimeras (PROTACs) for oral drug delivery: a drug metabolism and pharmacokinetics perspective. Drug Discovery Today |
Storer RI, Pike A, Swain NA, et al. (2017) Highly potent and selective NaV1.7 inhibitors for use as intravenous agents and chemical probes. Bioorganic & Medicinal Chemistry Letters |