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Andy Pike

Affiliations: 
Physiology Dept 
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"Andy Pike"
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Publications

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Schade M, Scott JS, Hayhow TG, et al. (2024) Structural and Physicochemical Features of Oral PROTACs. Journal of Medicinal Chemistry
Grimster NP, Gingipalli L, Balazs A, et al. (2023) Optimization of a Series of Novel, Potent and Selective Macrocyclic SYK Inhibitors. Bioorganic & Medicinal Chemistry Letters. 129352
Beaumont K, Pike A, Davies M, et al. (2022) ADME and DMPK considerations for the Discovery and Development of Antibody Drug Conjugates (ADCs). Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 1-44
Srivastava A, Pike A, Williamson B, et al. (2020) A novel method for preventing non-specific binding in equilibrium dialysis assays using Solutol® as an additive. Journal of Pharmaceutical Sciences
Barlaam B, Boiko S, Boyd S, et al. (2020) Novel potent and selective pyrazolylpyrimidine-based SYK inhibitors. Bioorganic & Medicinal Chemistry Letters. 127523
Pike A, Williamson B, Harlfinger S, et al. (2020) Optimising proteolysis-targeting chimeras (PROTACs) for oral drug delivery: a drug metabolism and pharmacokinetics perspective. Drug Discovery Today
Storer RI, Pike A, Swain NA, et al. (2017) Highly potent and selective NaV1.7 inhibitors for use as intravenous agents and chemical probes. Bioorganic & Medicinal Chemistry Letters
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