Seth L. Alper

Harvard Medical School, Boston, MA, United States 
"Seth Alper"
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Robert SM, Reeves BC, Kiziltug E, et al. (2023) The choroid plexus links innate immunity to CSF dysregulation in hydrocephalus. Cell. 186: 764-785.e21
Peikert K, Federti E, Matte A, et al. (2021) Therapeutic targeting of Lyn kinase to treat chorea-acanthocytosis. Acta Neuropathologica Communications. 9: 81
Robert SM, Reeves BC, Alper SL, et al. (2020) New drugs on the horizon for cerebral edema: what's in the clinical development pipeline? Expert Opinion On Investigational Drugs
Karimy JK, Reeves BC, Damisah E, et al. (2020) Inflammation in acquired hydrocephalus: pathogenic mechanisms and therapeutic targets. Nature Reviews. Neurology
Zhang J, Bhuiyan MIH, Zhang T, et al. (2020) Modulation of brain cation-Cl cotransport via the SPAK kinase inhibitor ZT-1a. Nature Communications. 11: 78
Watanabe M, Zhang J, Mansuri MS, et al. (2019) Developmentally regulated KCC2 phosphorylation is essential for dynamic GABA-mediated inhibition and survival. Science Signaling. 12
Duran D, Zeng X, Jin SC, et al. (2018) Mutations in Chromatin Modifier and Ephrin Signaling Genes in Vein of Galen Malformation. Neuron
Karimy JK, Zhang J, Kurland DB, et al. (2017) Inflammation-dependent cerebrospinal fluid hypersecretion by the choroid plexus epithelium in posthemorrhagic hydrocephalus. Nature Medicine
Zhang J, Gao G, Begum G, et al. (2016) Functional kinomics establishes a critical node of volume-sensitive cation-Cl(-) cotransporter regulation in the mammalian brain. Scientific Reports. 6: 35986
Kahle KT, Khanna AR, Alper SL, et al. (2015) K-Cl cotransporters, cell volume homeostasis, and neurological disease. Trends in Molecular Medicine. 21: 513-23
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