Edwin Thrower - Publications

Affiliations: 
1999-2002 Pharmacology Yale University, New Haven, CT 

33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Srinivasan P, Thrower EC, Loganathan G, Balamurugan AN, Subramanian VS, Gorelick FS, Said HM. Chronic Nicotine Exposure In Vivo and In Vitro Inhibits Vitamin B1 (Thiamin) Uptake by Pancreatic Acinar Cells. Plos One. 10: e0143575. PMID 26633299 DOI: 10.1371/journal.pone.0143575  0.92
2015 Zhao X, Zhang Y, Li J, Wan M, Zhu S, Guo H, Xiang J, Thrower EC, Tang W. Tissue Pharmacology of Da-Cheng-Qi Decoction in Experimental Acute Pancreatitis in Rats. Evidence-Based Complementary and Alternative Medicine : Ecam. 2015: 283175. PMID 26199633 DOI: 10.1155/2015/283175  0.92
2015 Thrower E. Pathologic cellular events in smoking-related pancreatitis. Cancers. 7: 723-35. PMID 25938854 DOI: 10.3390/cancers7020723  0.92
2013 Kolodecik T, Shugrue C, Ashat M, Thrower EC. Risk factors for pancreatic cancer: underlying mechanisms and potential targets. Frontiers in Physiology. 4: 415. PMID 24474939 DOI: 10.3389/fphys.2013.00415  0.92
2012 Orabi AI, Luo Y, Ahmad MU, Shah AU, Mannan Z, Wang D, Sarwar S, Muili KA, Shugrue C, Kolodecik TR, Singh VP, Lowe ME, Thrower E, Chen J, Husain SZ. IP3 receptor type 2 deficiency is associated with a secretory defect in the pancreatic acinar cell and an accumulation of zymogen granules. Plos One. 7: e48465. PMID 23185258 DOI: 10.1371/journal.pone.0048465  0.92
2012 Kolodecik TR, Shugrue CA, Thrower EC, Levin LR, Buck J, Gorelick FS. Activation of soluble adenylyl cyclase protects against secretagogue stimulated zymogen activation in rat pancreaic acinar cells. Plos One. 7: e41320. PMID 22844459 DOI: 10.1371/journal.pone.0041320  0.92
2012 Alexandre M, Uduman AK, Minervini S, Raoof A, Shugrue CA, Akinbiyi EO, Patel V, Shitia M, Kolodecik TR, Patton R, Gorelick FS, Thrower EC. Tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone initiates and enhances pancreatitis responses. American Journal of Physiology. Gastrointestinal and Liver Physiology. 303: G696-704. PMID 22837343 DOI: 10.1152/ajpgi.00138.2012  0.92
2012 Shugrue CA, Alexandre M, Diaz de Villalvilla A, Kolodecik TR, Young LH, Gorelick FS, Thrower EC. Cerulein hyperstimulation decreases AMP-activated protein kinase levels at the site of maximal zymogen activation. American Journal of Physiology. Gastrointestinal and Liver Physiology. 303: G723-32. PMID 22821946 DOI: 10.1152/ajpgi.00082.2012  0.92
2011 Alexandre M, Pandol SJ, Gorelick FS, Thrower EC. The emerging role of smoking in the development of pancreatitis. Pancreatology : Official Journal of the International Association of Pancreatology (Iap) ... [Et Al.]. 11: 469-74. PMID 21986098 DOI: 10.1159/000332196  0.92
2011 Reed AM, Husain SZ, Thrower E, Alexandre M, Shah A, Gorelick FS, Nathanson MH. Low extracellular pH induces damage in the pancreatic acinar cell by enhancing calcium signaling. The Journal of Biological Chemistry. 286: 1919-26. PMID 21084290 DOI: 10.1074/jbc.M110.158329  0.92
2011 Thrower EC, Yuan J, Usmani A, Liu Y, Jones C, Minervini SN, Alexandre M, Pandol SJ, Guha S. A novel protein kinase D inhibitor attenuates early events of experimental pancreatitis in isolated rat acini. American Journal of Physiology. Gastrointestinal and Liver Physiology. 300: G120-9. PMID 20947701 DOI: 10.1152/ajpgi.00300.2010  0.92
2010 Thrower EC, Gorelick FS, Husain SZ. Molecular and cellular mechanisms of pancreatic injury. Current Opinion in Gastroenterology. 26: 484-9. PMID 20651589 DOI: 10.1097/MOG.0b013e32833d119e  0.92
2009 Gorelick FS, Thrower E. The acinar cell and early pancreatitis responses. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 7: S10-4. PMID 19896090 DOI: 10.1016/j.cgh.2009.07.036  0.92
2009 Thrower EC, Wang J, Cheriyan S, Lugea A, Kolodecik TR, Yuan J, Reeve JR, Gorelick FS, Pandol SJ. Protein kinase C delta-mediated processes in cholecystokinin-8-stimulated pancreatic acini. Pancreas. 38: 930-5. PMID 19752773 DOI: 10.1097/MPA.0b013e3181b8476a  0.92
2009 Husain S, Thrower E. Molecular and cellular regulation of pancreatic acinar cell function. Current Opinion in Gastroenterology. 25: 466-71. PMID 19571746 DOI: 10.1097/MOG.0b013e32832ebfac  0.92
2009 Bhoomagoud M, Jung T, Atladottir J, Kolodecik TR, Shugrue C, Chaudhuri A, Thrower EC, Gorelick FS. Reducing extracellular pH sensitizes the acinar cell to secretagogue-induced pancreatitis responses in rats. Gastroenterology. 137: 1083-92. PMID 19454288 DOI: 10.1053/j.gastro.2009.05.041  0.92
2008 Thrower E, Husain S, Gorelick F. Molecular basis for pancreatitis. Current Opinion in Gastroenterology. 24: 580-5. PMID 19122498 DOI: 10.1097/MOG.0b013e32830b10e6  0.92
2008 Thrower EC, Osgood S, Shugrue CA, Kolodecik TR, Chaudhuri AM, Reeve JR, Pandol SJ, Gorelick FS. The novel protein kinase C isoforms -delta and -epsilon modulate caerulein-induced zymogen activation in pancreatic acinar cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 294: G1344-53. PMID 18388183 DOI: 10.1152/ajpgi.00020.2008  0.92
2008 Gorelick F, Pandol S, Thrower E. Protein kinase C in the pancreatic acinar cell. Journal of Gastroenterology and Hepatology. 23: S37-41. PMID 18336661 DOI: 10.1111/j.1440-1746.2007.05282.x  0.92
2006 McManaman JL, Reyland ME, Thrower EC. Secretion and fluid transport mechanisms in the mammary gland: comparisons with the exocrine pancreas and the salivary gland. Journal of Mammary Gland Biology and Neoplasia. 11: 249-68. PMID 17136613 DOI: 10.1007/s10911-006-9031-3  0.92
2006 Gorelick FS, Shugrue CA, Kolodecik TR, Thrower EC. Vacuolar adenosine triphosphatase and pancreatic acinar cell function. Journal of Gastroenterology and Hepatology. 21: S18-21. PMID 16958663 DOI: 10.1111/j.1440-1746.2006.04576.x  0.92
2006 Thrower EC, Diaz de Villalvilla AP, Kolodecik TR, Gorelick FS. Zymogen activation in a reconstituted pancreatic acinar cell system. American Journal of Physiology. Gastrointestinal and Liver Physiology. 290: G894-902. PMID 16339296 DOI: 10.1152/ajpgi.00373.2005  0.92
2005 Waterford SD, Kolodecik TR, Thrower EC, Gorelick FS. Vacuolar ATPase regulates zymogen activation in pancreatic acini. The Journal of Biological Chemistry. 280: 5430-4. PMID 15582989 DOI: 10.1074/jbc.M413513200  0.92
2003 Thrower EC, Choe CU, So SH, Jeon SH, Ehrlich BE, Yoo SH. A functional interaction between chromogranin B and the inositol 1,4,5-trisphosphate receptor/Ca2+ channel. The Journal of Biological Chemistry. 278: 49699-706. PMID 14506248 DOI: 10.1074/jbc.M309307200  0.92
2003 Leite MF, Thrower EC, Echevarria W, Koulen P, Hirata K, Bennett AM, Ehrlich BE, Nathanson MH. Nuclear and cytosolic calcium are regulated independently. Proceedings of the National Academy of Sciences of the United States of America. 100: 2975-80. PMID 12606721 DOI: 10.1073/pnas.0536590100  0.92
2002 Jiang QX, Thrower EC, Chester DW, Ehrlich BE, Sigworth FJ. Three-dimensional structure of the type 1 inositol 1,4,5-trisphosphate receptor at 24 A resolution. The Embo Journal. 21: 3575-81. PMID 12110570 DOI: 10.1093/emboj/cdf380  0.92
2002 Thrower EC, Park HY, So SH, Yoo SH, Ehrlich BE. Activation of the inositol 1,4,5-trisphosphate receptor by the calcium storage protein chromogranin A. The Journal of Biological Chemistry. 277: 15801-6. PMID 11842082 DOI: 10.1074/jbc.M110139200  0.92
2001 Koulen P, Thrower EC. Pharmacological modulation of intracellular Ca(2+) channels at the single-channel level. Molecular Neurobiology. 24: 65-86. PMID 11831555 DOI: 10.1385/MN:24:1-3:065  0.92
2001 Thrower EC, Hagar RE, Ehrlich BE. Regulation of Ins(1,4,5)P3 receptor isoforms by endogenous modulators. Trends in Pharmacological Sciences. 22: 580-6. PMID 11698102 DOI: 10.1016/S0165-6147(00)01809-5  0.92
2000 Thrower EC, Mobasheri H, Dargan S, Marius P, Lea EJ, Dawson AP. Interaction of luminal calcium and cytosolic ATP in the control of type 1 inositol (1,4,5)-trisphosphate receptor channels. The Journal of Biological Chemistry. 275: 36049-55. PMID 10956640 DOI: 10.1074/jbc.M000970200  0.92
1999 Thrower EC. Measurement of Ca2+ flux through Ins(1,4,5)P3 receptor-Ca2+ channels in lipid bilayers ("dip-tip" and "Schindler" methodology). Methods in Molecular Biology (Clifton, N.J.). 114: 221-33. PMID 10081021 DOI: 10.1385/1-59259-250-3:221  0.92
1998 Thrower EC, Lea EJ, Dawson AP. The effects of free [Ca2+] on the cytosolic face of the inositol (1,4,5)-trisphosphate receptor at the single channel level. The Biochemical Journal. 330: 559-64. PMID 9461556  0.92
1996 Thrower EC, Duclohier H, Lea EJ, Molle G, Dawson AP. The inositol 1,4,5-trisphosphate-gated Ca2+ channel: effect of the protein thiol reagent thimerosal on channel activity. The Biochemical Journal. 318: 61-6. PMID 8761453  0.92
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