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Qinheng Zheng, Ph.D. - Publications

Affiliations: 
2010-2014 College of Chemistry and Molecular Engineering Peking University, Beijing, Beijing Shi, China 
 2014-2020 Department of Chemistry Scripps Research Institute, La Jolla, La Jolla, CA, United States 
 2020- Department of Cellular and Molecular Pharmacology University of California, San Francisco, San Francisco, CA 
Area:
Chemistry
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22 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Zheng Q, Zhang Z, Guiley KZ, Shokat KM. Strain-release alkylation of Asp12 enables mutant selective targeting of K-Ras-G12D. Nature Chemical Biology. PMID 38443470 DOI: 10.1038/s41589-024-01565-w  0.352
2023 Malakoutikhah M, Mahran R, Gooran N, Masoumi A, Lundell K, Liljeblad A, Guiley K, Dai S, Zheng Q, Zhu L, Shokat KM, Kopra K, Härmä H. Nanomolar Protein Thermal Profiling with Modified Cyanine Dyes. Analytical Chemistry. PMID 38060502 DOI: 10.1021/acs.analchem.3c02844  0.398
2022 Vasta JD, Peacock DM, Zheng Q, Walker JA, Zhang Z, Zimprich CA, Thomas MR, Beck MT, Binkowski BF, Corona CR, Robers MB, Shokat KM. KRAS is vulnerable to reversible switch-II pocket engagement in cells. Nature Chemical Biology. PMID 35314814 DOI: 10.1038/s41589-022-00985-w  0.377
2022 Zheng Q, Peacock DM, Shokat KM. Drugging the Next Undruggable KRAS Allele-Gly12Asp. Journal of Medicinal Chemistry. PMID 35167298 DOI: 10.1021/acs.jmedchem.2c00099  0.363
2021 Garnar-Wortzel L, Bishop TR, Kitamura S, Milosevich N, Asiaban JN, Zhang X, Zheng Q, Chen E, Ramos AR, Ackerman CJ, Hampton EN, Chatterjee AK, Young TS, Hull MV, Sharpless KB, et al. Chemical Inhibition of ENL/AF9 YEATS Domains in Acute Leukemia. Acs Central Science. 7: 815-830. PMID 34079898 DOI: 10.1021/acscentsci.0c01550  0.388
2021 Zheng Q, Xu H, Wang H, Du WH, Wang N, Xiong H, Gu Y, Noodleman L, Sharpless KB, Yang G, Wu P. Sulfur [F]Fluoride Exchange Click Chemistry Enabled Ultrafast Late-Stage Radiosynthesis. Journal of the American Chemical Society. PMID 33630577 DOI: 10.1021/jacs.0c09306  0.478
2020 Kitamura S, Zheng Q, Woehl JL, Solania A, Chen E, Dillon N, Hull MV, Kotaniguchi M, Cappiello JR, Kitamura S, Nizet V, Sharpless KB, Wolan DW. SuFEx-enabled high-throughput medicinal chemistry. Journal of the American Chemical Society. PMID 32479075 DOI: 10.1021/Jacs.9B13652  0.504
2019 Zheng Q, Woehl JL, Kitamura S, Santos-Martins D, Smedley CJ, Li G, Forli S, Moses JE, Wolan DW, Sharpless KB. SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase. Proceedings of the National Academy of Sciences of the United States of America. PMID 31484779 DOI: 10.1073/Pnas.1909972116  0.653
2019 Barrow AS, Smedley CJ, Zheng Q, Li S, Dong J, Moses JE. The growing applications of SuFEx click chemistry. Chemical Society Reviews. PMID 31364998 DOI: 10.1039/C8Cs00960K  0.327
2019 Smedley CJ, Zheng Q, Gao B, Li S, Molino A, Duivenvoorden HM, Parker BS, Wilson DJD, Sharpless KB, Moses JE. Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides. Angewandte Chemie (International Ed. in English). PMID 30740848 DOI: 10.1002/Anie.201813761  0.638
2018 Gahtory D, Sen R, Pujari S, Li S, Zheng Q, Moses JE, Sharpless KB, Zuilhof H. Quantitative and Orthogonal Formation and Reactivity of SuFEx Platforms. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29949211 DOI: 10.1002/Chem.201802356  0.617
2017 Gao B, Zhang L, Zheng Q, Zhou F, Klivansky LM, Lu J, Liu Y, Dong J, Wu P, Sharpless KB. Bifluoride-catalysed sulfur(VI) fluoride exchange reaction for the synthesis of polysulfates and polysulfonates. Nature Chemistry. 9: 1083-1088. PMID 29064495 DOI: 10.1038/Nchem.2796  0.582
2017 Wang H, Zhou F, Ren G, Zheng Q, Chen H, Gao B, Klivansky L, Liu Y, Wu B, Xu Q, Lu J, Sharpless KB, Wu P. SuFEx-Based Polysulfonate Formation from Ethenesulfonyl Fluoride-Amine Adducts. Angewandte Chemie (International Ed. in English). PMID 28792119 DOI: 10.1002/Anie.201701160  0.595
2017 Ren G, Zheng Q, Wang H. Addition to "Aryl Fluorosulfate Trapped Staudinger Reduction". Organic Letters. PMID 28436666 DOI: 10.1021/Acs.Orglett.7B01187  0.301
2017 Zha GF, Zheng Q, Leng J, Wu P, Qin HL, Sharpless KB. Palladium-Catalyzed Fluorosulfonylvinylation of Organic Iodides. Angewandte Chemie (International Ed. in English). PMID 28370917 DOI: 10.1002/Anie.201701162  0.553
2017 Ren G, Zheng Q, Wang H. Aryl Fluorosulfate Trapped Staudinger Reduction. Organic Letters. PMID 28332844 DOI: 10.1021/Acs.Orglett.7B00406  0.366
2017 Wang H, Zhou F, Ren G, Zheng Q, Chen H, Gao B, Klivansky L, Liu Y, Wu B, Xu Q, Lu J, Sharpless KB, Wu P. Back Cover: SuFEx-Based Polysulfonate Formation from Ethenesulfonyl Fluoride-Amine Adducts (Angew. Chem. Int. Ed. 37/2017) Angewandte Chemie International Edition. 56: 11274-11274. DOI: 10.1002/Anie.201706481  0.546
2017 Wang H, Zhou F, Ren G, Zheng Q, Chen H, Gao B, Klivansky L, Liu Y, Wu B, Xu Q, Lu J, Sharpless KB, Wu P. Rücktitelbild: SuFEx-Based Polysulfonate Formation from Ethenesulfonyl Fluoride-Amine Adducts (Angew. Chem. 37/2017) Angewandte Chemie. 129: 11428-11428. DOI: 10.1002/Ange.201706481  0.558
2016 Zheng Q, Dong J, Sharpless KB. Ethenesulfonyl Fluoride (ESF): An On-Water Procedure for the Kilogram-Scale Preparation. The Journal of Organic Chemistry. PMID 27764941 DOI: 10.1021/Acs.Joc.6B01423  0.481
2016 Qin HL, Zheng Q, Bare GA, Wu P, Sharpless KB. A Heck-Matsuda Process for the Synthesis of β-Arylethenesulfonyl Fluorides: Selectively Addressable Bis-electrophiles for SuFEx Click Chemistry. Angewandte Chemie (International Ed. in English). PMID 27723200 DOI: 10.1002/Anie.201608807  0.551
2013 Jiang GJ, Zheng QH, Dou M, Zhuo LG, Meng W, Yu ZX. Mild-condition synthesis of allenes from alkynes and aldehydes mediated by tetrahydroisoquinoline (THIQ). The Journal of Organic Chemistry. 78: 11783-93. PMID 24266693 DOI: 10.1021/Jo4018183  0.551
2013 Zheng QH, Meng W, Jiang GJ, Yu ZX. CuI-catalyzed C1-alkynylation of tetrahydroisoquinolines (THIQs) by A3 reaction with tunable iminium ions. Organic Letters. 15: 5928-31. PMID 24237286 DOI: 10.1021/Ol402517E  0.523
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