Keith J. Buckler - Publications

Affiliations: 
1993-1999 University Laboratory of Physiology (now DPAG) University of Oxford, Oxford, United Kingdom 

75 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Pandit JJ, Huskens N, O'Donohoe PB, Turner PJ, Buckler KJ. Competitive Interactions between Halothane and Isoflurane at the Carotid Body and TASK Channels. Anesthesiology. PMID 32826405 DOI: 10.1097/ALN.0000000000003520  0.48
2018 O'Donohoe PB, Turner PJ, Huskens N, Buckler KJ, Pandit JJ. Influence of propofol on isolated neonatal rat carotid body glomus cell response to hypoxia and hypercapnia. Respiratory Physiology & Neurobiology. PMID 30389452 DOI: 10.1016/j.resp.2018.10.007  0.48
2018 O'Donohoe PB, Huskens N, Turner PJ, Pandit JJ, Buckler KJ. A1899, PK-THPP, ML365, and Doxapram inhibit endogenous TASK channels and excite calcium signaling in carotid body type-1 cells. Physiological Reports. 6: e13876. PMID 30284397 DOI: 10.14814/phy2.13876  0.48
2018 Bardsley EN, Davis H, Ajijola OA, Buckler KJ, Ardell JL, Shivkumar K, Paterson DJ. RNA Sequencing Reveals Novel Transcripts from Sympathetic Stellate Ganglia During Cardiac Sympathetic Hyperactivity. Scientific Reports. 8: 8633. PMID 29872217 DOI: 10.1038/s41598-018-26651-7  0.68
2018 Bardsley EN, Davis H, Buckler KJ, Paterson DJ. Neurotransmitter Switching Coupled to β-Adrenergic Signaling in Sympathetic Neurons in Prehypertensive States. Hypertension (Dallas, Tex. : 1979). PMID 29686017 DOI: 10.1161/HYPERTENSIONAHA.118.10844  0.68
2015 Huskens N, O'Donohoe P, Wickens JR, McCullagh JS, Buckler KJ, Pandit JJ. A method for continuous and stable perfusion of tissue and single cell preparations with accurate concentrations of volatile anaesthetics. Journal of Neuroscience Methods. PMID 26554517 DOI: 10.1016/j.jneumeth.2015.11.002  1
2015 Holmes AP, Turner PJ, Buckler KJ, Kumar P. Moderate inhibition of mitochondrial function augments carotid body hypoxic sensitivity. Pflugers Archiv : European Journal of Physiology. PMID 26490460 DOI: 10.1007/s00424-015-1745-x  1
2015 Hodson EJ, Nicholls LG, Turner PJ, Llyr R, Fielding JW, Douglas G, Ratnayaka I, Robbins PA, Pugh CW, Buckler KJ, Ratcliffe PJ, Bishop T. Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF-2 pathway. The Journal of Physiology. PMID 26337139 DOI: 10.1113/JP271050  1
2015 Buckler KJ, Turner PJ. Functional Properties of Mitochondria in the Type-1 Cell and Their Role in Oxygen Sensing. Advances in Experimental Medicine and Biology. 860: 69-80. PMID 26303469 DOI: 10.1007/978-3-319-18440-1_9  1
2015 Buckler KJ. TASK channels in arterial chemoreceptors and their role in oxygen and acid sensing. PflüGers Archiv : European Journal of Physiology. 467: 1013-25. PMID 25623783 DOI: 10.1007/s00424-015-1689-1  1
2014 Holmes AP, Turner PJ, Carter P, Leadbeater W, Ray CJ, Hauton D, Buckler KJ, Kumar P. Glycogen metabolism protects against metabolic insult to preserve carotid body function during glucose deprivation. The Journal of Physiology. 592: 4493-506. PMID 25063821 DOI: 10.1113/jphysiol.2014.276105  1
2014 Slingo ME, Turner PJ, Christian HC, Buckler KJ, Robbins PA. The von Hippel-Lindau Chuvash mutation in mice causes carotid-body hyperplasia and enhanced ventilatory sensitivity to hypoxia. Journal of Applied Physiology (Bethesda, Md. : 1985). 116: 885-92. PMID 24030664 DOI: 10.1152/japplphysiol.00530.2013  1
2013 Henrich M, Buckler KJ. Cytosolic calcium regulation in rat afferent vagal neurons during anoxia. Cell Calcium. 54: 416-27. PMID 24189167 DOI: 10.1016/j.ceca.2013.10.001  1
2013 Turner PJ, Buckler KJ. Oxygen and mitochondrial inhibitors modulate both monomeric and heteromeric TASK-1 and TASK-3 channels in mouse carotid body type-1 cells. The Journal of Physiology. 591: 5977-98. PMID 24042502 DOI: 10.1113/jphysiol.2013.262022  1
2013 Buckler KJ. Responses of glomus cells to hypoxia and acidosis. The Journal of Physiology. 591: 3667. PMID 23858042 DOI: 10.1113/jphysiol.2013.254029  1
2013 Bishop T, Talbot NP, Turner PJ, Nicholls LG, Pascual A, Hodson EJ, Douglas G, Fielding JW, Smith TG, Demetriades M, Schofield CJ, Robbins PA, Pugh CW, Buckler KJ, Ratcliffe PJ. Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2. The Journal of Physiology. 591: 3565-77. PMID 23690557 DOI: 10.1113/jphysiol.2012.247254  1
2013 Buckler KJ, Turner PJ. Oxygen sensitivity of mitochondrial function in rat arterial chemoreceptor cells. The Journal of Physiology. 591: 3549-63. PMID 23671162 DOI: 10.1113/jphysiol.2013.257741  1
2013 Li D, Nikiforova N, Lu CJ, Wannop K, McMenamin M, Lee CW, Buckler KJ, Paterson DJ. Targeted neuronal nitric oxide synthase transgene delivery into stellate neurons reverses impaired intracellular calcium transients in prehypertensive rats. Hypertension. 61: 202-7. PMID 23172925 DOI: 10.1161/HYPERTENSIONAHA.111.00105  1
2012 Buckler KJ. Effects of exogenous hydrogen sulphide on calcium signalling, background (TASK) K channel activity and mitochondrial function in chemoreceptor cells. PflüGers Archiv : European Journal of Physiology. 463: 743-54. PMID 22419174 DOI: 10.1007/s00424-012-1089-8  1
2012 Li D, Lee CW, Buckler K, Parekh A, Herring N, Paterson DJ. Abnormal intracellular calcium homeostasis in sympathetic neurons from young prehypertensive rats. Hypertension. 59: 642-9. PMID 22252398 DOI: 10.1161/HYPERTENSIONAHA.111.186460  1
2010 Pandit JJ, Collyer J, Buckler KJ. 'Hypoxic ventilatory decline' in the intracellular Ca2+ response to sustained isocapnic hypoxia in carotid body glomus cells. Advances in Experimental Medicine and Biology. 669: 209-12. PMID 20217351 DOI: 10.1007/978-1-4419-5692-7_42  1
2010 Pandit JJ, Winter V, Bayliss R, Buckler KJ. Differential effects of halothane and isoflurane on carotid body glomus cell intracellular Ca2+ and background K+ channel responses to hypoxia. Advances in Experimental Medicine and Biology. 669: 205-8. PMID 20217350 DOI: 10.1007/978-1-4419-5692-7_41  1
2010 Pandit JJ, Buckler KJ. Halothane and sevoflurane exert different degrees of inhibition on carotid body glomus cell intracellular Ca2+ response to hypoxia. Advances in Experimental Medicine and Biology. 669: 201-4. PMID 20217349 DOI: 10.1007/978-1-4419-5692-7_40  1
2010 Buckler KJ. Two-pore domain k(+) channels and their role in chemoreception. Advances in Experimental Medicine and Biology. 661: 15-30. PMID 20204721 DOI: 10.1007/978-1-60761-500-2_2  1
2009 Henrich M, Buckler KJ. Acid-evoked Ca2+ signalling in rat sensory neurones: effects of anoxia and aglycaemia. PflüGers Archiv : European Journal of Physiology. 459: 159-81. PMID 19806360 DOI: 10.1007/s00424-009-0715-6  1
2009 Pandit JJ, Buckler KJ. Differential effects of halothane and sevoflurane on hypoxia-induced intracellular calcium transients of neonatal rat carotid body type I cells. British Journal of Anaesthesia. 103: 701-10. PMID 19700444 DOI: 10.1093/bja/aep223  1
2008 Henrich M, Buckler KJ. Effects of anoxia and aglycemia on cytosolic calcium regulation in rat sensory neurons. Journal of Neurophysiology. 100: 456-73. PMID 18417627 DOI: 10.1152/jn.01380.2007  1
2008 Henrich M, Buckler KJ. Effects of anoxia, aglycemia, and acidosis on cytosolic Mg2+, ATP, and pH in rat sensory neurons. American Journal of Physiology. Cell Physiology. 294: C280-94. PMID 17977942 DOI: 10.1152/ajpcell.00345.2007  1
2007 Wang L, Henrich M, Buckler KJ, McMenamin M, Mee CJ, Sattelle DB, Paterson DJ. Neuronal nitric oxide synthase gene transfer decreases [Ca2+]i in cardiac sympathetic neurons. Journal of Molecular and Cellular Cardiology. 43: 717-25. PMID 17961591 DOI: 10.1016/j.yjmcc.2007.09.005  1
2007 Varas R, Wyatt CN, Buckler KJ. Modulation of TASK-like background potassium channels in rat arterial chemoreceptor cells by intracellular ATP and other nucleotides. The Journal of Physiology. 583: 521-36. PMID 17615104 DOI: 10.1113/jphysiol.2007.135657  1
2007 Buckler KJ. TASK-like potassium channels and oxygen sensing in the carotid body. Respiratory Physiology & Neurobiology. 157: 55-64. PMID 17416212 DOI: 10.1016/j.resp.2007.02.013  1
2006 Buckler KJ, Williams BA, Orozco RV, Wyatt CN. The role of TASK-like K+ channels in oxygen sensing in the carotid body. Novartis Foundation Symposium. 272: 73-85; discussion 85. PMID 16686430 DOI: 10.1002/9780470035009.ch7  1
2006 Varas R, Buckler KJ. Regulation of a TASK-like potassium channel in rat carotid body type I cells by ATP. Advances in Experimental Medicine and Biology. 580: 167-72; discussion 3. PMID 16683714 DOI: 10.1007/0-387-31311-7_25  1
2006 Weir K, López-Barneo J, Buckler KJ, Murphy MP, Rich PR, Gurney A, Evans AM, Gonzalez C, Archer SL, Duchen M, Chandel NS, Schumacker PT. Discussion Novartis Foundation Symposium. 272: 64-72.  1
2006 Duchen M, Gurney A, Nurse CA, Buckler KJ, López-Barneo J, Chandel NS, Gonzalez C, Schumacker PT, Sylvester JT, Rich PR, Archer SL, Kumar P, Ward JPT, Weir K. Final general discussion Novartis Foundation Symposium. 272: 274-279.  1
2006 Buckler KJ, Gurney A, Nurse CA, López-Barneo J, Kemp PJ, Kummer W, Sylvester JT, Kumar P, Archer SL, Chandel NS. Discussion Novartis Foundation Symposium. 272: 228-233.  1
2006 Buckler KJ, Gurney A, Nurse CA, López-Barneo J, Kemp PJ, Kummer W, Sylvester JT, Kumar P, Archer SL, Chandel NS. Discussion Novartis Foundation Symposium. 272: 228-233.  1
2006 Chandel NS, Kemp PJ, Prabhakar N, Duchen M, Acker H, Archer SL, Kummer W, Buckler KJ, López-Barneo J, Murphy MP, Sylvester JT, Schumacker PT, Gurney A, Peers C. Discussion Novartis Foundation Symposium. 272: 151-156.  1
2005 Weir EK, López-Barneo J, Buckler KJ, Archer SL. Acute oxygen-sensing mechanisms. The New England Journal of Medicine. 353: 2042-55. PMID 16282179 DOI: 10.1056/NEJMra050002  1
2005 Buckler KJ, Honoré E. The lipid-activated two-pore domain K+ channel TREK-1 is resistant to hypoxia: implication for ischaemic neuroprotection. The Journal of Physiology. 562: 213-22. PMID 15498799 DOI: 10.1113/jphysiol.2004.077503  1
2004 Buckler K, Honoré E. Molecular Strategies for Studying Oxygen-Sensitive K+ Channels Methods in Enzymology. 381: 233-256. PMID 15063679 DOI: 10.1016/S0076-6879(04)81017-6  1
2004 Wyatt CN, Buckler KJ. The effect of mitochondrial inhibitors on membrane currents in isolated neonatal rat carotid body type I cells. The Journal of Physiology. 556: 175-91. PMID 14724184 DOI: 10.1113/jphysiol.2003.058131  1
2004 Williams BA, Buckler KJ. Biophysical properties and metabolic regulation of a TASK-like potassium channel in rat carotid body type 1 cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 286: L221-30. PMID 14504065 DOI: 10.1152/ajplung.00010.2003  1
2003 Wyatt CN, Buckler KJ. The effect of methanandamide on isolated type I cells. Advances in Experimental Medicine and Biology. 536: 123-7. PMID 14635657  1
2003 Wyatt CN, Buckler KJ. Effect of mitochondrial inhibitors on type I cells. Advances in Experimental Medicine and Biology. 536: 55-8. PMID 14635649  1
2000 Dasso LL, Buckler KJ, Vaughan-Jones RD. Interactions between hypoxia and hypercapnic acidosis on calcium signaling in carotid body type I cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 279: L36-42. PMID 10893200  1
2000 Tsai KL, Vaughan-Jones RD, Buckler KJ. A dual acid-influx transport system in the carotid body type I cell. Acid influx in carotid body type I cells. Advances in Experimental Medicine and Biology. 475: 723-32. PMID 10849714 DOI: 10.1007/0-306-46825-5_72  1
2000 Williams BA, Buckler KJ. Identification of an oxygen-sensitive potassium channel in neonatal rat carotid body type I cells. Advances in Experimental Medicine and Biology. 475: 419-24. PMID 10849682 DOI: 10.1007/0-306-46825-5_40  1
2000 Buckler KJ, Williams BA, Honore E. An oxygen-, acid- and anaesthetic-sensitive TASK-like background potassium channel in rat arterial chemoreceptor cells. The Journal of Physiology. 525: 135-42. PMID 10811732  1
1999 Buckler KJ. Background leak K+-currents and oxygen sensing in carotid body type 1 cells. Respiration Physiology. 115: 179-87. PMID 10385032 DOI: 10.1016/S0034-5687(99)00015-8  1
1998 Buckler KJ, Vaughan-Jones RD. Effects of mitochondrial uncouplers on intracellular calcium, pH and membrane potential in rat carotid body type I cells. The Journal of Physiology. 513: 819-33. PMID 9824720 DOI: 10.1111/j.1469-7793.1998.819ba.x  1
1997 Buckler KJ. A novel oxygen-sensitive potassium current in rat carotid body type I cells. The Journal of Physiology. 498: 649-62. PMID 9051577  1
1997 Dasso LL, Buckler KJ, Vaughan-Jones RD. Muscarinic and nicotinic receptors raise intracellular Ca2+ levels in rat carotid body type I cells. The Journal of Physiology. 498: 327-38. PMID 9032682  1
1996 Dasso LL, Buckler KJ, Vaughan-Jones RD. Acetylcholine elevates intracellular Ca2+ via muscarinic and nicotinic receptors in rat carotid body type I cells. Advances in Experimental Medicine and Biology. 410: 239-44. PMID 9030305  1
1996 Buckler KJ. Role of potassium channels in hypoxic chemoreception in rat carotid body type-I cells. Advances in Experimental Medicine and Biology. 410: 83-7. PMID 9030281  1
1996 Lagadic-Gossmann D, Buckler KJ, Le Prigent K, Feuvray D. Altered Ca2+ handling in ventricular myocytes isolated from diabetic rats. The American Journal of Physiology. 270: H1529-37. PMID 8928857  1
1995 Peers C, Buckler KJ. Transduction of chemostimuli by the type I carotid body cell. The Journal of Membrane Biology. 144: 1-9. PMID 7595937 DOI: 10.1007/BF00238411  1
1994 Buckler KJ, Vaughan-Jones RD. Effects of hypoxia on membrane potential and intracellular calcium in rat neonatal carotid body type I cells. The Journal of Physiology. 476: 423-8. PMID 8057251  1
1994 Buckler KJ, Vaughan-Jones RD. Effects of hypercapnia on membrane potential and intracellular calcium in rat carotid body type I cells. The Journal of Physiology. 478: 157-71. PMID 7965831  1
1994 Peers C, Wyatt CN, Buckler KJ. Actions of nicotinic agonists on isolated type I cells of the neonatal rat carotid body. Advances in Experimental Medicine and Biology. 360: 155-7. PMID 7872076 DOI: 10.1007/978-1-4615-2572-1_17  1
1994 Buckler KJ, Vaughan-Jones RD. Role of intracellular pH and [Ca2+]i in acid chemoreception in type-I cells of the carotid body. Advances in Experimental Medicine and Biology. 360: 41-55. PMID 7532906  1
1993 Buckler KJ, Vaughan-Jones RD. Effects of acidic stimuli on intracellular calcium in isolated type I cells of the neonatal rat carotid body. PflüGers Archiv : European Journal of Physiology. 425: 22-7. PMID 8272380 DOI: 10.1007/BF00374499  1
1993 Vaughan-Jones RD, Buckler KJ, Peers C, Nye PC. Regulation of intracellular pH in type I cells of the neonatal rat carotid body. Advances in Experimental Medicine and Biology. 337: 251-6. PMID 8109408  1
1993 Buckler KJ, Vaughan-Jones RD, Peers C, Lagadic-Gossmann D, Nye PC. The modulation of intracellular pH in carotid body glomus cells by extracellular pH and pCO2. Advances in Experimental Medicine and Biology. 337: 103-9. PMID 8109390  1
1992 Lagadic-Gossmann D, Vaughan-Jones RD, Buckler KJ. Adrenaline and extracellular ATP switch between two modes of acid extrusion in the guinea-pig ventricular myocyte. The Journal of Physiology. 458: 385-407. PMID 1338791  1
1992 Lagadic-Gossmann D, Buckler KJ, Vaughan-Jones RD. Role of bicarbonate in pH recovery from intracellular acidosis in the guinea-pig ventricular myocyte. The Journal of Physiology. 458: 361-84. PMID 1302269  1
1991 Buckler KJ, Vaughan-Jones RD, Peers C, Nye PC. Intracellular pH and its regulation in isolated type I carotid body cells of the neonatal rat. The Journal of Physiology. 436: 107-29. PMID 2061827  1
1991 Buckler KJ, Vaughan-Jones RD, Peers C, Lagadic-Gossmann D, Nye PC. Effects of extracellular pH, PCO2 and HCO3- on intracellular pH in isolated type-I cells of the neonatal rat carotid body. The Journal of Physiology. 444: 703-21. PMID 1822566  1
1990 Buckler KJ, Vaughan-Jones RD. Application of a new pH-sensitive fluoroprobe (carboxy-SNARF-1) for intracellular pH measurement in small, isolated cells. PflüGers Archiv : European Journal of Physiology. 417: 234-9. PMID 2084617 DOI: 10.1007/BF00370705  1
1990 Cohen RD, Woods HF, Unwin R, Buckler KJ, Gasser RNA, Iles RA, Beech JS. Bicarbonate and cytoplasmic pH The Lancet. 335: 1586-1588. PMID 1972500 DOI: 10.1016/0140-6736(90)91410-C  1
1990 Buckler KJ, Denyer JC, Vaughan-Jones RD, Brown HF. Intracellular pH regulation in rabbit isolated sino-atrial node cells Journal of Physiology. 426: 22P.  1
1990 Buckler KJ, Vaughan-Jones RD, Lagadic-Gossmann D. Measurement of pH(i) in isolated single cells using the dual-emission fluoroprobe carboxy-SNARF-1 Journal of Physiology. 430: 2P.  1
1990 Buckler KJ, Nye PCG, Peers C, Vaughan-Jones RD. Regulation of intracellular pH in single type I carotid body cells isolated from the neonatal rat Journal of Physiology. 423: 65P.  1
1990 Buckler KJ, Gasser RNA. Bicarbonate and cytoplasmic pH (III) Lancet. 335: 1587.  1
1990 Buckler KJ, Nye PCG, Peers C, Vaughan-Jones. Effects of simulated respiratory and metabolic acidosis/alkalosis on pH(i) in isolated type I carotid body cells from the neonatal rat Journal of Physiology. 426: 66P.  1
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