| Year |
Citation |
Score |
| 2024 |
Ortiz-Vega N, Lobato AG, Canic T, Zhu Y, Lazopulo S, Syed S, Zhai RG. Regulation of proteostasis by sleep through autophagy in models of Alzheimer's disease. Life Science Alliance. 7. PMID 39237365 DOI: 10.26508/lsa.202402681 |
0.533 |
|
| 2023 |
Lobato AG, Ortiz-Vega N, Zhu Y, Neupane D, Meier KK, Zhai RG. Copper enhances aggregational toxicity of mutant huntingtin in a Drosophila model of Huntington's Disease. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 1870: 166928. PMID 38660915 DOI: 10.1016/j.bbadis.2023.166928 |
0.558 |
|
| 2023 |
Jin Y, Zhai RG. Presynaptic Cytomatrix Proteins. Advances in Neurobiology. 33: 23-42. PMID 37615862 DOI: 10.1007/978-3-031-34229-5_2 |
0.304 |
|
| 2023 |
Zhu Y, Lobato AG, Rebelo AP, Canic T, Ortiz Vega N, Tao X, Syed S, Yanick C, Saporta M, Shy M, Perfetti R, Shendelman S, Zuchner SL, Zhai RG. Sorbitol reduction via AT-007 (govorestat) ameliorates synaptic dysfunction and neurodegeneration in models of sorbitol dehydrogenase deficiency. Jci Insight. PMID 37014713 DOI: 10.1172/jci.insight.164954 |
0.612 |
|
| 2022 |
Zhang S, Zhu Y, Lu J, Liu Z, Lobato AG, Zeng W, Liu J, Qiang J, Zeng S, Zhang Y, Liu C, Liu J, He Z, Zhai RG, Li D. Specific binding of Hsp27 and phosphorylated Tau mitigates abnormal Tau aggregation-induced pathology. Elife. 11. PMID 36048712 DOI: 10.7554/eLife.79898 |
0.529 |
|
| 2022 |
Tao X, Zhu Y, Diaz-Perez Z, Yu SH, Foley JR, Stewart TM, Casero RA, Steet R, Zhai RG. Phenylbutyrate modulates polyamine acetylase and ameliorates Snyder-Robinson syndrome in a Drosophila model and patient cells. Jci Insight. 7. PMID 35801587 DOI: 10.1172/jci.insight.158457 |
0.571 |
|
| 2022 |
Zhu Y, Lobato AG, Zhai RG, Pinto M. Human Nmnat1 Promotes Autophagic Clearance of Amyloid Plaques in a Model of Alzheimer's Disease. Frontiers in Aging Neuroscience. 14: 852972. PMID 35401143 DOI: 10.3389/fnagi.2022.852972 |
0.532 |
|
| 2021 |
Liu J, Tao X, Zhu Y, Li C, Ruan K, Diaz-Perez Z, Rai P, Wang H, Zhai RG. NMNAT promotes glioma growth through regulating post-translational modifications of P53 to inhibit apoptosis. Elife. 10. PMID 34919052 DOI: 10.7554/eLife.70046 |
0.601 |
|
| 2020 |
Hu J, Liu J, Zhu Y, Diaz-Perez Z, Sheridan M, Royer H, Leibensperger R, Maizel D, Brand L, Popendorf KJ, Gaston CJ, Zhai RG. Exposure to Aerosolized Algal Toxins in South Florida Increases Short- and Long-Term Health Risk in Model of Aging. Toxins. 12. PMID 33322328 DOI: 10.3390/toxins12120787 |
0.499 |
|
| 2020 |
Cortese A, Zhu Y, Rebelo AP, Negri S, Courel S, Abreu L, Bacon CJ, Bai Y, Bis-Brewer DM, Bugiardini E, Buglo E, Danzi MC, Feely SME, Athanasiou-Fragkouli A, Haridy NA, ... ... Zhai RG, et al. Author Correction: Biallelic mutations in SORD cause a common and potentially treatable hereditary neuropathy with implications for diabetes. Nature Genetics. PMID 32457452 DOI: 10.1038/S41588-020-0649-7 |
0.736 |
|
| 2020 |
Cortese A, Zhu Y, Rebelo AP, Negri S, Courel S, Abreu L, Bacon CJ, Bai Y, Bis-Brewer DM, Bugiardini E, Buglo E, Danzi MC, Feely SME, Athanasiou-Fragkouli A, Haridy NA, ... ... Zhai RG, et al. Biallelic mutations in SORD cause a common and potentially treatable hereditary neuropathy with implications for diabetes. Nature Genetics. PMID 32367058 DOI: 10.1038/S41588-020-0615-4 |
0.759 |
|
| 2020 |
Ma X, Zhu Y, Lu J, Xie J, Li C, Shin WS, Qiang J, Liu J, Dou S, Xiao Y, Wang C, Jia C, Long H, Yang J, Fang Y, ... ... Zhai RG, et al. Nicotinamide mononucleotide adenylyltransferase uses its NAD substrate-binding site to chaperone phosphorylated Tau. Elife. 9. PMID 32250733 DOI: 10.7554/Elife.51859 |
0.591 |
|
| 2019 |
Park J, Zhu Y, Tao X, Brazill JM, Li C, Wuchty S, Zhai RG. MicroRNA miR-1002 Enhances NMNAT-Mediated Stress Response by Modulating Alternative Splicing. Iscience. 19: 1048-1064. PMID 31522116 DOI: 10.1016/j.isci.2019.08.052 |
0.582 |
|
| 2019 |
Zhu Y, Li C, Tao X, Brazill JM, Park J, Diaz-Perez Z, Zhai RG. Nmnat restores neuronal integrity by neutralizing mutant Huntingtin aggregate-induced progressive toxicity. Proceedings of the National Academy of Sciences of the United States of America. PMID 31484760 DOI: 10.1073/pnas.1904563116 |
0.672 |
|
| 2019 |
Lukacs M, Gilley J, Zhu Y, Orsomando G, Angeletti C, Liu J, Yang X, Park J, Hopkin RJ, Coleman MP, Zhai RG, Stottmann RW. Severe biallelic loss-of-function mutations in nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) in two fetuses with fetal akinesia deformation sequence. Experimental Neurology. 112961. PMID 31136762 DOI: 10.1016/J.Expneurol.2019.112961 |
0.584 |
|
| 2019 |
Zhu Y, Liu J, Park J, Rai P, Zhai RG. Subcellular compartmentalization of NAD and its role in cancer: A sereNADe of metabolic melodies. Pharmacology & Therapeutics. PMID 30974124 DOI: 10.1016/J.Pharmthera.2019.04.002 |
0.527 |
|
| 2019 |
Li C, Bademci G, Subasioglu A, Diaz-Horta O, Zhu Y, Liu J, Mitchell TG, Abad C, Seyhan S, Duman D, Cengiz FB, Tokgoz-Yilmaz S, Blanton SH, Farooq A, Walz K, ... Zhai RG, et al. Dysfunction of , encoding the GRB2-related adaptor protein, is linked to sensorineural hearing loss. Proceedings of the National Academy of Sciences of the United States of America. PMID 30610177 DOI: 10.1073/Pnas.1810951116 |
0.668 |
|
| 2018 |
Brazill JM, Zhu Y, Li C, Zhai RG. Quantitative Cell Biology of Neurodegeneration in Drosophila Through Unbiased Analysis of Fluorescently Tagged Proteins Using ImageJ. Journal of Visualized Experiments : Jove. PMID 30124668 DOI: 10.3791/58041 |
0.652 |
|
| 2018 |
Brazill JM, Cruz B, Zhu Y, Zhai RG. Nmnat mitigates sensory dysfunction in a model of paclitaxel-induced peripheral neuropathy. Disease Models & Mechanisms. PMID 29716954 DOI: 10.1242/dmm.032938 |
0.588 |
|
| 2018 |
Li C, Brazill JM, Liu S, Bello C, Zhu Y, Morimoto M, Cascio L, Pauly R, Diaz-Perez Z, Malicdan MCV, Wang H, Boccuto L, Schwartz CE, Gahl WA, Boerkoel CF, ... Zhai RG, et al. Publisher Correction: Spermine synthase deficiency causes lysosomal dysfunction and oxidative stress in models of Snyder-Robinson syndrome. Nature Communications. 9: 337. PMID 29348635 DOI: 10.1038/s41467-017-02462-8 |
0.69 |
|
| 2017 |
Li C, Brazill JM, Liu S, Bello C, Zhu Y, Morimoto M, Cascio L, Pauly R, Diaz-Perez Z, Malicdan MCV, Wang H, Boccuto L, Schwartz CE, Gahl WA, Boerkoel CF, ... Zhai RG, et al. Spermine synthase deficiency causes lysosomal dysfunction and oxidative stress in models of Snyder-Robinson syndrome. Nature Communications. 8: 1257. PMID 29097652 DOI: 10.1038/s41467-017-01289-7 |
0.733 |
|
| 2017 |
Gall T, Valkanas E, Bello C, Markello T, Adams C, Bone WP, Brandt AJ, Brazill JM, Carmichael L, Davids M, Davis J, Diaz-Perez Z, Draper D, Elson J, Flynn ED, ... ... Zhai RG, et al. Defining Disease, Diagnosis, and Translational Medicine within a Homeostatic Perturbation Paradigm: The National Institutes of Health Undiagnosed Diseases Program Experience. Frontiers in Medicine. 4: 62. PMID 28603714 DOI: 10.3389/Fmed.2017.00062 |
0.695 |
|
| 2017 |
Brazill JM, Li C, Zhu Y, Zhai RG. NMNAT: It's an NAD(+) synthase… It's a chaperone… It's a neuroprotector. Current Opinion in Genetics & Development. 44: 156-162. PMID 28445802 DOI: 10.1016/j.gde.2017.03.014 |
0.665 |
|
| 2016 |
Ruetenik AL, Ocampo A, Ruan K, Zhu Y, Li C, Zhai RG, Barrientos A. Attenuation of polyglutamine-induced toxicity by enhancement of mitochondrial OXPHOS in yeast and fly models of aging. Microbial Cell (Graz, Austria). 3: 338-351. PMID 28357370 DOI: 10.15698/Mic2016.08.518 |
0.596 |
|
| 2015 |
Ruan K, Zhu Y, Li C, Brazill JM, Zhai RG. Alternative splicing of Drosophila Nmnat functions as a switch to enhance neuroprotection under stress. Nature Communications. 6: 10057. PMID 26616331 DOI: 10.1038/ncomms10057 |
0.614 |
|
| 2013 |
Ali YO, Li-Kroeger D, Bellen HJ, Zhai RG, Lu HC. NMNATs, evolutionarily conserved neuronal maintenance factors. Trends in Neurosciences. 36: 632-40. PMID 23968695 DOI: 10.1016/J.Tins.2013.07.002 |
0.746 |
|
| 2013 |
Kitay BM, McCormack R, Wang Y, Tsoulfas P, Zhai RG. Mislocalization of neuronal mitochondria reveals regulation of Wallerian degeneration and NMNAT/WLD(S)-mediated axon protection independent of axonal mitochondria. Human Molecular Genetics. 22: 1601-14. PMID 23314018 DOI: 10.1093/Hmg/Ddt009 |
0.715 |
|
| 2010 |
Ali YO, Kitay BM, Zhai RG. Dealing with misfolded proteins: examining the neuroprotective role of molecular chaperones in neurodegeneration. Molecules (Basel, Switzerland). 15: 6859-87. PMID 20938400 DOI: 10.3390/Molecules15106859 |
0.726 |
|
| 2008 |
Zhai RG, Zhang F, Hiesinger PR, Cao Y, Haueter CM, Bellen HJ. NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration. Nature. 452: 887-91. PMID 18344983 DOI: 10.1038/nature06721 |
0.714 |
|
| 2006 |
Zhai RG, Cao Y, Hiesinger PR, Zhou Y, Mehta SQ, Schulze KL, Verstreken P, Bellen HJ. Drosophila NMNAT maintains neural integrity independent of its NAD synthesis activity. Plos Biology. 4: e416. PMID 17132048 DOI: 10.1371/journal.pbio.0040416 |
0.791 |
|
| 2006 |
Hiesinger PR, Zhai RG, Zhou Y, Koh TW, Mehta SQ, Schulze KL, Cao Y, Verstreken P, Clandinin TR, Fischbach KF, Meinertzhagen IA, Bellen HJ. Activity-independent prespecification of synaptic partners in the visual map of Drosophila. Current Biology : Cb. 16: 1835-43. PMID 16979562 DOI: 10.1016/j.cub.2006.07.047 |
0.787 |
|
| 2005 |
Hiesinger PR, Fayyazuddin A, Mehta SQ, Rosenmund T, Schulze KL, Zhai RG, Verstreken P, Cao Y, Zhou Y, Kunz J, Bellen HJ. The v-ATPase V0 subunit a1 is required for a late step in synaptic vesicle exocytosis in Drosophila. Cell. 121: 607-20. PMID 15907473 DOI: 10.1016/J.Cell.2005.03.012 |
0.723 |
|
| 2005 |
Mehta SQ, Hiesinger PR, Beronja S, Zhai RG, Schulze KL, Verstreken P, Cao Y, Zhou Y, Tepass U, Crair MC, Bellen HJ. Mutations in Drosophila sec15 reveal a function in neuronal targeting for a subset of exocyst components. Neuron. 46: 219-32. PMID 15848801 DOI: 10.1016/j.neuron.2005.02.029 |
0.783 |
|
| 2004 |
Zhai RG, Bellen HJ. Hauling t-SNAREs on the microtubule highway. Nature Cell Biology. 6: 918-9. PMID 15459718 DOI: 10.1038/ncb1004-918 |
0.481 |
|
| 2004 |
Zhai RG, Bellen HJ. The architecture of the active zone in the presynaptic nerve terminal. Physiology (Bethesda, Md.). 19: 262-70. PMID 15381754 DOI: 10.1152/physiol.00014.2004 |
0.466 |
|
| 2003 |
Verstreken P, Koh TW, Schulze KL, Zhai RG, Hiesinger PR, Zhou Y, Mehta SQ, Cao Y, Roos J, Bellen HJ. Synaptojanin is recruited by endophilin to promote synaptic vesicle uncoating. Neuron. 40: 733-48. PMID 14622578 DOI: 10.1016/S0896-6273(03)00644-5 |
0.786 |
|
| 2003 |
Zhai RG, Hiesinger PR, Koh TW, Verstreken P, Schulze KL, Cao Y, Jafar-Nejad H, Norga KK, Pan H, Bayat V, Greenbaum MP, Bellen HJ. Mapping Drosophila mutations with molecularly defined P element insertions. Proceedings of the National Academy of Sciences of the United States of America. 100: 10860-5. PMID 12960394 DOI: 10.1073/Pnas.1832753100 |
0.699 |
|
| 2003 |
Shapira M, Zhai RG, Dresbach T, Bresler T, Torres VI, Gundelfinger ED, Ziv NE, Garner CC. Unitary assembly of presynaptic active zones from Piccolo-Bassoon transport vesicles. Neuron. 38: 237-52. PMID 12718858 DOI: 10.1016/S0896-6273(03)00207-1 |
0.557 |
|
| 2002 |
Garner CC, Zhai RG, Gundelfinger ED, Ziv NE. Molecular mechanisms of CNS synaptogenesis. Trends in Neurosciences. 25: 243-51. PMID 11972960 DOI: 10.1016/S0166-2236(02)02152-5 |
0.566 |
|
| 2001 |
Bresler T, Ramati Y, Zamorano PL, Zhai R, Garner CC, Ziv NE. The dynamics of SAP90/PSD-95 recruitment to new synaptic junctions. Molecular and Cellular Neurosciences. 18: 149-67. PMID 11520177 DOI: 10.1006/mcne.2001.1012 |
0.555 |
|
| 2001 |
Zhai RG, Vardinon-Friedman H, Cases-Langhoff C, Becker B, Gundelfinger ED, Ziv NE, Garner CC. Assembling the presynaptic active zone: a characterization of an active one precursor vesicle. Neuron. 29: 131-43. PMID 11182086 DOI: 10.1016/S0896-6273(01)00185-4 |
0.54 |
|
| 2000 |
Zhai R, Olias G, Chung WJ, Lester RA, tom Dieck S, Langnaese K, Kreutz MR, Kindler S, Gundelfinger ED, Garner CC. Temporal appearance of the presynaptic cytomatrix protein bassoon during synaptogenesis. Molecular and Cellular Neurosciences. 15: 417-28. PMID 10833299 DOI: 10.1006/Mcne.2000.0839 |
0.684 |
|
| 2000 |
Fenster SD, Chung WJ, Zhai R, Cases-Langhoff C, Voss B, Garner AM, Kaempf U, Kindler S, Gundelfinger ED, Garner CC. Piccolo, a presynaptic zinc finger protein structurally related to bassoon. Neuron. 25: 203-14. PMID 10707984 DOI: 10.1016/S0896-6273(00)80883-1 |
0.787 |
|
| 1999 |
Richter K, Langnaese K, Kreutz MR, Olias G, Zhai R, Scheich H, Garner CC, Gundelfinger ED. Presynaptic cytomatrix protein bassoon is localized at both excitatory and inhibitory synapses of rat brain. The Journal of Comparative Neurology. 408: 437-48. PMID 10340516 DOI: 10.1002/(Sici)1096-9861(19990607)408:3<437::Aid-Cne9>3.0.Co;2-5 |
0.564 |
|
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