Robert C. Elston - Publications

Affiliations: 
Case Western Reserve University School of Medicine, Cleveland, OH, United States 
Area:
Public Health, Biostatistics Biology

280 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Elston RC. An Accidental Genetic Epidemiologist. Annual Review of Genomics and Human Genetics. PMID 31935127 DOI: 10.1146/Annurev-Genom-103119-125052  0.409
2020 Wang H, Sofer T, Zhang X, Elston RC, Redline S, Zhu X. Local Ancestry Inference in Large Pedigrees. Scientific Reports. 10: 189. PMID 31932708 DOI: 10.1038/S41598-019-57039-W  0.397
2018 Elston RC. Fisher's influence on me. Genetic Epidemiology. PMID 30298598 DOI: 10.1002/Gepi.22165  0.315
2018 Wang T, Xue X, Xie X, Ye K, Zhu X, Elston RC. Adjustment for covariates using summary statistics of genome-wide association studies. Genetic Epidemiology. PMID 30238496 DOI: 10.1002/Gepi.22148  0.398
2018 Pereira S, Katzmarzyk PT, Gomes TN, Elston R, Maia J. How Consistent are Genetic Factors in Explaining Leisure-Time Physical Activity and Sport Participation? The Portuguese Healthy Families Study. Twin Research and Human Genetics : the Official Journal of the International Society For Twin Studies. 1-9. PMID 29976260 DOI: 10.1017/Thg.2018.47  0.326
2018 Song YE, Lee S, Park K, Elston RC, Yang HJ, Won S. ONETOOL for the analysis of family-based big data. Bioinformatics (Oxford, England). PMID 29596615 DOI: 10.1093/Bioinformatics/Bty180  0.323
2017 Sun X, Chandar AK, Canto MI, Thota PN, Brock M, Shaheen NJ, Beer DG, Wang JS, Falk GW, Iyer PG, Abrams JA, Venkat-Ramani M, Veigl M, Miron A, Willis J, ... ... Elston R, et al. Genomic regions associated with susceptibility to Barrett's esophagus and esophageal adenocarcinoma in African Americans: The cross BETRNet admixture study. Plos One. 12: e0184962. PMID 29073141 DOI: 10.1371/Journal.Pone.0184962  0.332
2017 Huang X, Elston RC, Rosa GJ, Mayer J, Ye Z, Kitchner T, Brilliant MH, Page D, Hebbring SJ. Applying Family Analyses to Electronic Health Records to Facilitate Genetic Research. Bioinformatics (Oxford, England). PMID 28968884 DOI: 10.1093/Bioinformatics/Btx569  0.377
2017 Liu M, Moon S, Wang L, Kim S, Kim YJ, Hwang MY, Kim YJ, Elston RC, Kim BJ, Won S. On the association analysis of CNV data: a fast and robust family-based association method. Bmc Bioinformatics. 18: 217. PMID 28420343 DOI: 10.1186/S12859-017-1622-Z  0.385
2016 Sun X, Elston R, Falk GW, Grady WM, Faulx A, Mittal SK, Canto MI, Shaheen NJ, Wang JS, Iyer PG, Abrams JA, Willis JE, Guda K, Markowitz S, Barnholtz-Sloan JS, et al. Linkage and related analyses of Barrett's esophagus and its associated adenocarcinomas. Molecular Genetics & Genomic Medicine. 4: 407-419. PMID 27468417 DOI: 10.1002/Mgg3.211  0.42
2016 Fecteau RE, Kong J, Kresak A, Brock W, Song Y, Fujioka H, Elston R, Willis JE, Lynch JP, Markowitz SD, Guda K, Chak A. Association Between Germline Mutation in VSIG10L and Familial Barrett Neoplasia. Jama Oncology. PMID 27467440 DOI: 10.1001/Jamaoncol.2016.2054  0.322
2016 Wang L, Lee S, Gim J, Qiao D, Cho M, Elston RC, Silverman EK, Won S. Family-Based Rare Variant Association Analysis: A Fast and Efficient Method of Multivariate Phenotype Association Analysis. Genetic Epidemiology. PMID 27312886 DOI: 10.1002/Gepi.21985  0.393
2016 Williams RC, Elston RC, Kumar P, Knowler WC, Abboud HE, Adler S, Bowden DW, Divers J, Freedman BI, Igo RP, Ipp E, Iyengar SK, Kimmel PL, Klag MJ, Kohn O, et al. Selecting SNPs informative for African, American Indian and European Ancestry: application to the Family Investigation of Nephropathy and Diabetes (FIND). Bmc Genomics. 17: 325. PMID 27142425 DOI: 10.1186/S12864-016-2654-X  0.365
2016 Sun X, Elston RC, Barnholtz-Sloan JS, Falk GW, Grady WM, Faulx A, Mittal SK, Canto M, Shaheen NJ, Wang JS, Iyer PG, Abrams JA, Tian YD, Willis JE, Guda K, et al. Predicting Barrett's esophagus in Families: An Esophagus Translational Research Network (BETRNet) Model Fitting Clinical Data to a Familial Paradigm. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 26929243 DOI: 10.1158/1055-9965.Epi-15-0832  0.319
2016 Wei C, Elston RC, Lu Q. A weighted U statistic for association analyses considering genetic heterogeneity. Statistics in Medicine. PMID 26833871 DOI: 10.1002/Sim.6877  0.407
2016 Markowitz SD, Nock NL, Schmit SL, Stadler ZK, Joseph V, Zhang L, Willis JE, Scacheri P, Veigl M, Adams MD, Raskin L, Sullivan JF, Stratton K, Shia J, Ellis N, ... ... Elston RC, et al. A Germline Variant on Chromosome 4q31.1 Associates with Susceptibility to Developing Colon Cancer Metastasis. Plos One. 11: e0146435. PMID 26751797 DOI: 10.1371/Journal.Pone.0146435  0.35
2016 Sun X, Onstad LE, Elston R, Falk GW, Grady WM, Canto MI, Shaheen N, Wang J, Iyer P, Abrams JA, Vaughan T, Chak A. 840 Combining GWAS With Linkage Analysis Identifies a SNP Associated With Barrett's Esophagus And Esophageal Adenocarcinoma Gastroenterology. 150: S178. DOI: 10.1016/S0016-5085(16)30683-7  0.335
2015 Kim Y, Lee Y, Lee S, Kim NH, Lim J, Kim YJ, Oh JH, Min H, Lee M, Seo HJ, Lee SH, Sung J, Cho NH, Kim BJ, Han BG, ... Elston RC, et al. On the Estimation of Heritability with Family-Based and Population-Based Samples. Biomed Research International. 2015: 671349. PMID 26339629 DOI: 10.1155/2015/671349  0.342
2015 Iyengar SK, Sedor JR, Freedman BI, Kao WH, Kretzler M, Keller BJ, Abboud HE, Adler SG, Best LG, Bowden DW, Burlock A, Chen YD, Cole SA, Comeau ME, Curtis JM, ... ... Elston RC, et al. Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND). Plos Genetics. 11: e1005352. PMID 26305897 DOI: 10.1371/Journal.Pgen.1005352  0.382
2015 Huang Y, Wang C, Yao Y, Zuo X, Chen S, Xu C, Zhang H, Lu Q, Chang L, Wang F, Wang P, Zhang R, Hu Z, Song Q, Yang X, ... ... Elston R, et al. Molecular Basis of Gene-Gene Interaction: Cyclic Cross-Regulation of Gene Expression and Post-GWAS Gene-Gene Interaction Involved in Atrial Fibrillation. Plos Genetics. 11: e1005393. PMID 26267381 DOI: 10.1371/Journal.Pgen.1005393  0.319
2015 Morris N, Elston RC, Barnholtz-Sloan JS, Sun X. Novel approaches to the analysis of family data in genetic epidemiology. Frontiers in Genetics. 6: 27. PMID 25705217 DOI: 10.3389/Fgene.2015.00027  0.428
2015 Ochs-Balcom HM, Sun X, Chen Y, Barnholtz-Sloan J, Erwin DO, Jandorf L, Sucheston-Campbell L, Elston RC. Putative linkage signals identified for breast cancer in African American families. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 24: 442-7. PMID 25477366 DOI: 10.1158/1055-9965.Epi-14-1131  0.323
2014 Lee Y, Park S, Moon S, Lee J, Elston RC, Lee W, Won S. On the analysis of a repeated measure design in genome-wide association analysis. International Journal of Environmental Research and Public Health. 11: 12283-303. PMID 25464127 DOI: 10.3390/Ijerph111212283  0.364
2014 Ginns EI, Galdzicka M, Elston RC, Song YE, Paul SM, Egeland JA. Disruption of sonic hedgehog signaling in Ellis-van Creveld dwarfism confers protection against bipolar affective disorder. Molecular Psychiatry. PMID 25311364 DOI: 10.1038/Mp.2014.118  0.344
2014 Wang YJ, Tayo BO, Bandyopadhyay A, Wang H, Feng T, Franceschini N, Tang H, Gao J, Sung YJ, Elston RC, Williams SM, Cooper RS, Mu TW, Zhu X. The association of the vanin-1 N131S variant with blood pressure is mediated by endoplasmic reticulum-associated degradation and loss of function. Plos Genetics. 10: e1004641. PMID 25233454 DOI: 10.1371/Journal.Pgen.1004641  0.342
2014 Grigoroiu-Serbanescu M, Rietschel M, Hauser J, Czerski PM, Herms S, Sun X, Wickramaratne P, Elston RC. Commingling analysis of age-of-onset in bipolar I disorder and the morbid risk for major psychoses in first degree relatives of bipolar I probands. Journal of Affective Disorders. 168: 197-204. PMID 25063958 DOI: 10.1016/J.Jad.2014.06.054  0.32
2014 Schrodi SJ, Mukherjee S, Shan Y, Tromp G, Sninsky JJ, Callear AP, Carter TC, Ye Z, Haines JL, Brilliant MH, Crane PK, Smelser DT, Elston RC, Weeks DE. Genetic-based prediction of disease traits: prediction is very difficult, especially about the future. Frontiers in Genetics. 5: 162. PMID 24917882 DOI: 10.3389/Fgene.2014.00162  0.365
2014 Sun X, Lu Q, Mukherjee S, Mukheerjee S, Crane PK, Elston R, Ritchie MD. Analysis pipeline for the epistasis search - statistical versus biological filtering. Frontiers in Genetics. 5: 106. PMID 24817878 DOI: 10.3389/Fgene.2014.00106  0.319
2014 Lin CY, Xing G, Ku HC, Elston RC, Xing C. Enhancing the power to detect low-frequency variants in genome-wide screens. Genetics. 196: 1293-302. PMID 24496013 DOI: 10.1534/Genetics.113.160739  0.35
2014 Li M, He Z, Zhang M, Zhan X, Wei C, Elston RC, Lu Q. A generalized genetic random field method for the genetic association analysis of sequencing data. Genetic Epidemiology. 38: 242-53. PMID 24482034 DOI: 10.1002/Gepi.21790  0.373
2014 Sun X, Chak A, Falk GW, Grady WM, Kinnard MF, mittal sK, Canto MI, Shaheen NJ, Wang JS, Iyer PG, Abrams JA, Willis J, Markowitz S, Barnholtz-Sloan J, Brock W, ... Elston R, et al. Sa1826 Predicting Barrett's Esophagus in Families of Patients With Barrett's Esophagus: A BETRNet Model Fitting Clinical Data to a Genetic Paradigm Gastroenterology. 146: S-305. DOI: 10.1016/S0016-5085(14)61095-7  0.314
2013 Thameem F, Igo RP, Freedman BI, Langefeld C, Hanson RL, Schelling JR, Elston RC, Duggirala R, Nicholas SB, Goddard KA, Divers J, Guo X, Ipp E, Kimmel PL, Meoni LA, et al. A genome-wide search for linkage of estimated glomerular filtration rate (eGFR) in the Family Investigation of Nephropathy and Diabetes (FIND). Plos One. 8: e81888. PMID 24358131 DOI: 10.1371/Journal.Pone.0081888  0.404
2013 Song YE, Elston RC. The null distribution of likelihood-ratio statistics in the conditional-logistic linkage model. Frontiers in Genetics. 4: 244. PMID 24312121 DOI: 10.3389/Fgene.2013.00244  0.375
2013 Clerget-Darpoux F, Elston RC. Will formal genetics become dispensable? Human Heredity. 76: 47-52. PMID 24107572 DOI: 10.1159/000354571  0.383
2013 Song YE, Elston RC. PedWiz: a web-based tool for pedigree informatics. Frontiers in Genetics. 4: 189. PMID 24093024 DOI: 10.3389/Fgene.2013.00189  0.378
2013 Sun X, Elston R, Morris N, Zhu X. What is the significance of difference in phenotypic variability across SNP genotypes? American Journal of Human Genetics. 93: 390-7. PMID 23910463 DOI: 10.1016/J.Ajhg.2013.06.017  0.344
2013 Thompson CL, Fink SP, Lutterbaugh JD, Elston RC, Veigl ML, Markowitz SD, Li L. Genetic Variation in 15-Hydroxyprostaglandin Dehydrogenase and Colon Cancer Susceptibility Plos One. 8. PMID 23717544 DOI: 10.1371/Journal.Pone.0064122  0.329
2013 Wang X, Morris NJ, Zhu X, Elston RC. A variance component based multi-marker association test using family and unrelated data. Bmc Genetics. 14: 17. PMID 23497289 DOI: 10.1186/1471-2156-14-17  0.438
2013 Satagopan JM, Elston RC. Evaluation of removable statistical interaction for binary traits. Statistics in Medicine. 32: 1164-90. PMID 23018341 DOI: 10.1002/Sim.5628  0.317
2012 Liu Y, Maxwell S, Feng T, Zhu X, Elston RC, Koyutürk M, Chance MR. Gene, pathway and network frameworks to identify epistatic interactions of single nucleotide polymorphisms derived from GWAS data. Bmc Systems Biology. 6: S15. PMID 23281810 DOI: 10.1186/1752-0509-6-S3-S15  0.361
2012 Zhu X, Feng T, Elston RC. Linkage-disequilibrium-based binning misleads the interpretation of genome-wide association studies. American Journal of Human Genetics. 91: 965-8; author reply . PMID 23122590 DOI: 10.1016/J.Ajhg.2012.05.029  0.38
2012 Amos CI, Schnell A, Chen WV, Elston RC. Model-free tests for genetic linkage. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. Unit1.8. PMID 23074068 DOI: 10.1002/0471142905.Hg0108S75  0.382
2012 Sun X, Vengoechea J, Elston R, Chen Y, Amos CI, Armstrong G, Bernstein JL, Claus E, Davis F, Houlston RS, Il'yasova D, Jenkins RB, Johansen C, Lai R, Lau CC, et al. A variable age of onset segregation model for linkage analysis, with correction for ascertainment, applied to glioma. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 21: 2242-51. PMID 22962404 DOI: 10.1158/1055-9965.Epi-12-0703  0.398
2012 Lu Q, Wei C, Ye C, Li M, Elston RC. A likelihood ratio-based Mann-Whitney approach finds novel replicable joint gene action for type 2 diabetes. Genetic Epidemiology. 36: 583-93. PMID 22760990 DOI: 10.1002/Gepi.21651  0.39
2012 Yang BZ, Han S, Kranzler HR, Farrer LA, Elston RC, Gelernter J. Autosomal linkage scan for loci predisposing to comorbid dependence on multiple substances. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 159: 361-9. PMID 22354695 DOI: 10.1002/Ajmg.B.32037  0.409
2012 Chak A, Chen Y, Vengoechea J, Canto MI, Elston R, Falk GW, Grady WM, Guda K, Kinnard M, Markowitz S, Mittal S, Prasad G, Shaheen N, Willis JE, Barnholtz-Sloan JS. Variation in age at cancer diagnosis in familial versus nonfamilial Barrett's esophagus. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 21: 376-83. PMID 22178570 DOI: 10.1158/1055-9965.Epi-11-0927  0.322
2011 Sun X, Namkung J, Zhu X, Elston RC. Capability of common SNPs to tag rare variants. Bmc Proceedings. 5: S88. PMID 22373521 DOI: 10.1186/1753-6561-5-S9-S88  0.329
2011 Song YE, Namkung J, Shields RW, Baechle DJ, Song S, Elston RC. A method to detect single-nucleotide polymorphisms accounting for a linkage signal using covariate-based affected relative pair linkage analysis. Bmc Proceedings. 5: S84. PMID 22373405 DOI: 10.1186/1753-6561-5-S9-S84  0.398
2011 Guo W, Elston RC, Zhu X. Evaluation of a LASSO regression approach on the unrelated samples of Genetic Analysis Workshop 17. Bmc Proceedings. 5: S12. PMID 22373385 DOI: 10.1186/1753-6561-5-S9-S12  0.399
2011 Feng T, Elston RC, Zhu X. A novel method to detect rare variants using both family and unrelated case-control data. Bmc Proceedings. 5: S80. PMID 22373319 DOI: 10.1186/1753-6561-5-S9-S80  0.387
2011 Wang X, Qin H, Morris NJ, Zhu X, Elston RC. Testing gene-environment interactions in gene-based association studies. Bmc Proceedings. 5: S26. PMID 22373316 DOI: 10.1186/1753-6561-5-S9-S26  0.371
2011 Qin H, Elston RC, Zhu X. Interrogating population structure and its impact on association tests. Bmc Proceedings. 5: S25. PMID 22373290 DOI: 10.1186/1753-6561-5-S9-S25  0.393
2011 Shetty PB, Qin H, Namkung J, Elston RC, Zhu X. Estimating heritability using family and unrelated individuals data. Bmc Proceedings. 5: S34. PMID 22373039 DOI: 10.1186/1753-6561-5-S9-S34  0.359
2011 Schnell AH, Sun X, Igo RP, Elston RC. Some capabilities for model-based and model-free linkage analysis using the program package S.A.G.E. (Statistical Analysis for Genetic Epidemiology). Human Heredity. 72: 237-46. PMID 22189466 DOI: 10.1159/000331672  0.388
2011 Ye C, Cui Y, Wei C, Elston RC, Zhu J, Lu Q. A non-parametric method for building predictive genetic tests on high-dimensional data. Human Heredity. 71: 161-70. PMID 21778735 DOI: 10.1159/000327299  0.333
2011 Chen Y, Wang W, Zhou Y, Shields R, Chanda SK, Elston RC, Li J. In silico gene prioritization by integrating multiple data sources. Plos One. 6: e21137. PMID 21731658 DOI: 10.1371/Journal.Pone.0021137  0.307
2011 Li M, Ye C, Fu W, Elston RC, Lu Q. Detecting genetic interactions for quantitative traits with U-statistics. Genetic Epidemiology. 35: 457-68. PMID 21618602 DOI: 10.1002/Gepi.20594  0.397
2011 Feng T, Elston RC, Zhu X. Detecting rare and common variants for complex traits: sibpair and odds ratio weighted sum statistics (SPWSS, ORWSS). Genetic Epidemiology. 35: 398-409. PMID 21594893 DOI: 10.1002/Gepi.20588  0.403
2011 Palmer LJ, Barnes KC, Burton PR, Chen H, Cookson WO, Deichmann KA, Elston RC, Holloway JW, Jacobs KB, Laitinen T, Wjst M. Meta-analysis for linkage to asthma and atopy in the chromosome 5q31-33 candidate region. Human Molecular Genetics. 10: 891-99. PMID 21523954 DOI: 10.1093/Hmg/10.8.891  0.356
2011 Elston RC. 2010 William Allan Award introduction: Jürg Ott. American Journal of Human Genetics. 88: 262-3. PMID 21516614 DOI: 10.1016/J.Ajhg.2011.02.012  0.321
2011 Cubells JF, Sun X, Li W, Bonsall RW, McGrath JA, Avramopoulos D, Lasseter VK, Wolyniec PS, Tang YL, Mercer K, Pulver AE, Elston RC. Linkage analysis of plasma dopamine β-hydroxylase activity in families of patients with schizophrenia. Human Genetics. 130: 635-43. PMID 21509519 DOI: 10.1007/S00439-011-0989-6  0.395
2011 Igo RP, Iyengar SK, Nicholas SB, Goddard KA, Langefeld CD, Hanson RL, Duggirala R, Divers J, Abboud H, Adler SG, Arar NH, Horvath A, Elston RC, Bowden DW, Guo X, et al. Genomewide linkage scan for diabetic renal failure and albuminuria: the FIND study. American Journal of Nephrology. 33: 381-9. PMID 21454968 DOI: 10.1159/000326763  0.376
2011 Mathew G, Song Y, Elston R. Interval estimation of familial correlations from pedigrees. Statistical Applications in Genetics and Molecular Biology. 10: Article 11. PMID 21381436 DOI: 10.2202/1544-6115.1573  0.317
2011 Stein CM, Lu Q, Elston RC, Freebairn LA, Hansen AJ, Shriberg LD, Taylor HG, Lewis BA, Iyengar SK. Heritability estimation for speech-sound traits with developmental trajectories. Behavior Genetics. 41: 184-91. PMID 20623172 DOI: 10.1007/S10519-010-9378-5  0.313
2011 Grigoroiu-Serbanescu M, Elston R. Incongruent psychosis in bipolar i disorder: heritability and importance for genetic association studies European Psychiatry. 26: 213-213. DOI: 10.1016/S0924-9338(11)71923-X  0.349
2010 Wang X, Elston RC, Zhu X. The meaning of interaction. Human Heredity. 70: 269-77. PMID 21150212 DOI: 10.1159/000321967  0.3
2010 Sinsheimer JS, Elston RC, Fu WJ. Gene-gene interaction in maternal and perinatal research. Journal of Biomedicine & Biotechnology. 2010. PMID 20798776 DOI: 10.1155/2010/853612  0.343
2010 Gray-McGuire C, Guda K, Adrianto I, Lin CP, Natale L, Potter JD, Newcomb P, Poole EM, Ulrich CM, Lindor N, Goode EL, Fridley BL, Jenkins R, Le Marchand L, Casey G, ... ... Elston R, et al. Confirmation of linkage to and localization of familial colon cancer risk haplotype on chromosome 9q22. Cancer Research. 70: 5409-18. PMID 20551049 DOI: 10.1158/0008-5472.Can-10-0188  0.725
2010 Beall CM, Cavalleri GL, Deng L, Elston RC, Gao Y, Knight J, Li C, Li JC, Liang Y, McCormack M, Montgomery HE, Pan H, Robbins PA, Shianna KV, Tam SC, et al. Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlanders. Proceedings of the National Academy of Sciences of the United States of America. 107: 11459-64. PMID 20534544 DOI: 10.1073/Pnas.1002443107  0.352
2010 Lu Q, Cui Y, Ye C, Wei C, Elston RC. Bagging optimal ROC curve method for predictive genetic tests, with an application for rheumatoid arthritis. Journal of Biopharmaceutical Statistics. 20: 401-14. PMID 20309765 DOI: 10.1080/10543400903572811  0.361
2010 Sun X, Elston R, Barnholtz-Sloan J, Falk G, Grady WM, Kinnard M, Mittal SK, Willis JE, Markowitz S, Brock W, Chak A. A segregation analysis of Barrett's esophagus and associated adenocarcinomas. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 19: 666-74. PMID 20200424 DOI: 10.1158/1055-9965.Epi-09-1136  0.418
2010 Yang R, Li L, Seidelmann SB, Shen GQ, Sharma S, Rao S, Abdullah KG, Mackinlay KG, Elston RC, Chen Q, Topol EJ, Wang QK. A genome-wide linkage scan identifies multiple quantitative trait loci for HDL-cholesterol levels in families with premature CAD and MI. Journal of Lipid Research. 51: 1442-51. PMID 20075193 DOI: 10.1194/Jlr.M004325  0.392
2010 Zhu X, Feng T, Li Y, Lu Q, Elston RC. Detecting rare variants for complex traits using family and unrelated data. Genetic Epidemiology. 34: 171-87. PMID 19847924 DOI: 10.1002/Gepi.20449  0.408
2010 Ochs-Balcom HM, Guo X, Yonebayashi T, Wiesner G, Elston RC. Program update and novel use of the DESPAIR program to design a genome-wide linkage study using relative pairs. Human Heredity. 69: 45-51. PMID 19797908 DOI: 10.1159/000243153  0.319
2010 Lu Q, Obuchowski N, Won S, Zhu X, Elston RC. Using the optimal robust receiver operating characteristic (ROC) curve for predictive genetic tests. Biometrics. 66: 586-93. PMID 19508241 DOI: 10.1111/J.1541-0420.2009.01278.X  0.389
2010 Sun X, Elston R, Barnholtz-Sloan J, Falk GW, Grady WM, Kinnard MF, Mittal SK, Willis J, Markowitz S, Brock WE, Chak A. 16 A Segregation Analysis of Barrett's Esophagus and Associated Adenocarcinomas Gastroenterology. 138: S-2-S-3. DOI: 10.1016/S0016-5085(10)60010-8  0.416
2009 Lu Q, Song Y, Wang X, Won S, Cui Y, Elston RC. The effect of multiple genetic variants in predicting the risk of type 2 diabetes. Bmc Proceedings. 3: S49. PMID 20018041 DOI: 10.1186/1753-6561-3-S7-S49  0.357
2009 Sun X, Feng T, Song Y, Elston RC, Zhu X. Comparison of a unified analysis approach for family and unrelated samples with the transmission-disequilibrium test to study associations of hypertension in the Framingham Heart Study. Bmc Proceedings. 3: S22. PMID 20018012 DOI: 10.1186/1753-6561-3-S7-S22  0.376
2009 Feng Q, Abraham J, Feng T, Song Y, Elston RC, Zhu X. A method to correct for population structure using a segregation model. Bmc Proceedings. 3: S104. PMID 20017968 DOI: 10.1186/1753-6561-3-S7-S104  0.399
2009 Gray-McGuire C, Bochud M, Goodloe R, Elston RC. Genetic association tests: a method for the joint analysis of family and case-control data. Human Genomics. 4: 2-20. PMID 19951892 DOI: 10.1186/1479-7364-4-1-2  0.727
2009 Morris NJ, Elston R, Stein CM. Calculating asymptotic significance levels of the constrained likelihood ratio test with application to multivariate genetic linkage analysis. Statistical Applications in Genetics and Molecular Biology. 8: Article 39. PMID 19799558 DOI: 10.2202/1544-6115.1456  0.343
2009 Jun G, Guo H, Klein BE, Klein R, Wang JJ, Mitchell P, Miao H, Lee KE, Joshi T, Buck M, Chugha P, Bardenstein D, Klein AP, Bailey-Wilson JE, Gong X, ... ... Elston RC, et al. EPHA2 is associated with age-related cortical cataract in mice and humans. Plos Genetics. 5: e1000584. PMID 19649315 DOI: 10.1371/Journal.Pgen.1000584  0.3
2009 Wan L, Sun K, Ding Q, Cui Y, Li M, Wen Y, Elston RC, Qian M, Fu WJ. Hybridization modeling of oligonucleotide SNP arrays for accurate DNA copy number estimation. Nucleic Acids Research. 37: e117. PMID 19586935 DOI: 10.1093/Nar/Gkp559  0.321
2009 Guda K, Natale L, Lutterbaugh J, Wiesner GL, Lewis S, Tanner SM, Tomsic J, Valle L, de la Chapelle A, Elston RC, Willis J, Markowitz SD. Infrequent detection of germline allele-specific expression of TGFBR1 in lymphoblasts and tissues of colon cancer patients. Cancer Research. 69: 4959-61. PMID 19509225 DOI: 10.1158/0008-5472.Can-09-0225  0.318
2009 Chak A, Falk G, Grady WM, Kinnard M, Elston R, Mittal S, King JF, Willis JE, Kondru A, Brock W, Barnholtz-Sloan J. Assessment of familiality, obesity, and other risk factors for early age of cancer diagnosis in adenocarcinomas of the esophagus and gastroesophageal junction. The American Journal of Gastroenterology. 104: 1913-21. PMID 19491834 DOI: 10.1038/Ajg.2009.241  0.332
2009 Won S, Morris N, Lu Q, Elston RC. Choosing an optimal method to combine P-values. Statistics in Medicine. 28: 1537-53. PMID 19266501 DOI: 10.1002/Sim.3569  0.341
2009 Namkung J, Elston RC, Yang JM, Park T. Identification of gene-gene interactions in the presence of missing data using the multifactor dimensionality reduction method. Genetic Epidemiology. 33: 646-56. PMID 19241410 DOI: 10.1002/Gepi.20416  0.355
2009 Sinha R, Igo RP, Saini SK, Elston RC, Luo Y. Bayesian intervals for linkage locations. Genetic Epidemiology. 33: 604-16. PMID 19194982 DOI: 10.1002/Gepi.20412  0.357
2009 Won S, Kim S, Elston RC. Phase uncertainty in case-control association studies. Genetic Epidemiology. 33: 463-78. PMID 19194981 DOI: 10.1002/Gepi.20399  0.322
2009 Stein CM, Elston RC. Finding genes underlying human disease Clinical Genetics. 75: 101-106. PMID 18783406 DOI: 10.1111/J.1399-0004.2008.01083.X  0.327
2009 Wang T, Ho G, Ye K, Strickler H, Elston RC. A partial least-square approach for modeling gene-gene and gene-environment interactions when multiple markers are genotyped. Genetic Epidemiology. 33: 6-15. PMID 18615621 DOI: 10.1002/Gepi.20351  0.362
2008 Stein CM, Zalwango S, Malone LL, Won S, Mayanja-Kizza H, Mugerwa RD, Leontiev DV, Thompson CL, Cartier KC, Elston RC, Iyengar SK, Boom WH, Whalen CC. Genome scan of M. tuberculosis infection and disease in Ugandans. Plos One. 3: e4094. PMID 19116662 DOI: 10.1371/Journal.Pone.0004094  0.355
2008 Lou XY, Chen GB, Yan L, Ma JZ, Mangold JE, Zhu J, Elston RC, Li MD. A combinatorial approach to detecting gene-gene and gene-environment interactions in family studies. American Journal of Human Genetics. 83: 457-67. PMID 18834969 DOI: 10.1016/J.Ajhg.2008.09.001  0.332
2008 Larkin EK, Patel SR, Elston RC, Gray-McGuire C, Zhu X, Redline S. Using linkage analysis to identify quantitative trait loci for sleep apnea in relationship to body mass index. Annals of Human Genetics. 72: 762-73. PMID 18754839 DOI: 10.1111/J.1469-1809.2008.00472.X  0.707
2008 Ochs-Balcom HM, Cicek MS, Thompson CL, Tucker TC, Elston RC, J Plummer S, Casey G, Li L. Association of vitamin D receptor gene variants, adiposity and colon cancer. Carcinogenesis. 29: 1788-93. PMID 18628249 DOI: 10.1093/Carcin/Bgn166  0.344
2008 Won S, Elston RC. The power of independent types of genetic information to detect association in a case-control study design. Genetic Epidemiology. 32: 731-56. PMID 18481783 DOI: 10.1002/Gepi.20341  0.39
2008 Seidlerová J, Bochud M, Staessen JA, Cwynar M, Dolejsová M, Kuznetsova T, Nawrot T, Olszanecka A, Stolarz K, Thijs L, Wojciechowska W, Struijker-Boudier HA, Kawecka-Jaszcz K, Elston RC, Fagard R, et al. Heritability and intrafamilial aggregation of arterial characteristics. Journal of Hypertension. 26: 721-8. PMID 18327082 DOI: 10.1097/Hjh.0B013E3282F4D1E7  0.336
2008 Lu Q, Elston RC. Using the optimal receiver operating characteristic curve to design a predictive genetic test, exemplified with type 2 diabetes. American Journal of Human Genetics. 82: 641-51. PMID 18319073 DOI: 10.1016/J.Ajhg.2007.12.025  0.373
2008 Daley D, Lewis S, Platzer P, MacMillen M, Willis J, Elston RC, Markowitz SD, Wiesner GL. Identification of susceptibility genes for cancer in a genome-wide scan: results from the colon neoplasia sibling study. American Journal of Human Genetics. 82: 723-36. PMID 18313025 DOI: 10.1016/j.ajhg.2008.01.007  0.575
2008 Zhu X, Li S, Cooper RS, Elston RC. A unified association analysis approach for family and unrelated samples correcting for stratification. American Journal of Human Genetics. 82: 352-65. PMID 18252216 DOI: 10.1016/J.Ajhg.2007.10.009  0.4
2008 Schelling JR, Abboud HE, Nicholas SB, Pahl MV, Sedor JR, Adler SG, Arar NH, Bowden DW, Elston RC, Freedman BI, Goddard KA, Guo X, Hanson RL, Ipp E, Iyengar SK, et al. Genome-wide scan for estimated glomerular filtration rate in multi-ethnic diabetic populations: the Family Investigation of Nephropathy and Diabetes (FIND). Diabetes. 57: 235-43. PMID 18003762 DOI: 10.2337/Db07-0313  0.372
2008 Li MD, Ma JZ, Payne TJ, Lou XY, Zhang D, Dupont RT, Elston RC. Genome-wide linkage scan for nicotine dependence in European Americans and its converging results with African Americans in the Mid-South Tobacco Family sample Molecular Psychiatry. 13: 407-416. PMID 17579606 DOI: 10.1038/Sj.Mp.4002038  0.377
2007 Xing C, Torres-Caban M, Wang T, Lu Q, Xing G, Elston RC. Linkage studies of catechol-O-methyltransferase (COMT) and dopamine-beta-hydroxylase (DBH) cDNA expression levels. Bmc Proceedings. 1: S95. PMID 18466599 DOI: 10.1186/1753-6561-1-S1-S95  0.353
2007 Xing G, Xing C, Lu Q, Elston RC. A logistic mixture model for a family-based association study. Bmc Proceedings. 1: S44. PMID 18466543 DOI: 10.1186/1753-6561-1-S1-S44  0.418
2007 Song K, Lu Q, Lin X, Waterworth D, Elston RC. Genome-wide association studies using an adaptive two-stage analysis for a case-control design. Bmc Proceedings. 1: S147. PMID 18466491 DOI: 10.1186/1753-6561-1-S1-S147  0.616
2007 Wang T, Lu Q, Torres-Caban M, Elston RC. Two-stage analysis strategy for identifying the IgM quantitative trait locus. Bmc Proceedings. 1: S139. PMID 18466482 DOI: 10.1186/1753-6561-1-S1-S139  0.378
2007 Dupuis J, Albers K, Allen-Brady K, Cho K, Elston RC, Kappen HJ, Tang H, Thomas A, Thomson G, Tsung E, Yang Q, Zhang W, Zhao K, Zheng G, Ziegler JT. Effect of linkage disequilibrium between markers in linkage and association analyses. Genetic Epidemiology. 31: S139-48. PMID 18046770 DOI: 10.1002/Gepi.20291  0.329
2007 Yang Q, Biernacka JM, Chen MH, Houwing-Duistermaat JJ, Bergemann TL, Basu S, Fan R, Liu L, Bourgey M, Clerget-Darpoux F, Lin WY, Elston RC, Cupples LA, Apprey V, Cui J, et al. Using linkage and association to identify and model genetic effects: summary of GAW15 Group 4. Genetic Epidemiology. 31: S34-42. PMID 18046758 DOI: 10.1002/Gepi.20278  0.422
2007 Iyengar SK, Elston RC. The genetic basis of complex traits: rare variants or "common gene, common disease"? Methods in Molecular Biology (Clifton, N.J.). 376: 71-84. PMID 17984539 DOI: 10.1007/978-1-59745-389-9_6  0.368
2007 Lee SY, Chung Y, Elston RC, Kim Y, Park T. Log-linear model-based multifactor dimensionality reduction method to detect gene gene interactions. Bioinformatics (Oxford, England). 23: 2589-95. PMID 17872915 DOI: 10.1093/Bioinformatics/Btm396  0.357
2007 Shen GQ, Li L, Girelli D, Seidelmann SB, Rao S, Fan C, Park JE, Xi Q, Li J, Hu Y, Olivieri O, Marchant K, Barnard J, Corrocher R, Elston R, et al. An LRP8 variant is associated with familial and premature coronary artery disease and myocardial infarction. American Journal of Human Genetics. 81: 780-91. PMID 17847002 DOI: 10.1086/521581  0.372
2007 Thompson CL, Klein BE, Klein R, Xu Z, Capriotti J, Joshi T, Leontiev D, Lee KE, Elston RC, Iyengar SK. Complement factor H and hemicentin-1 in age-related macular degeneration and renal phenotypes. Human Molecular Genetics. 16: 2135-48. PMID 17591627 DOI: 10.1093/Hmg/Ddm164  0.334
2007 Ochs-Balcom HM, Falk G, Grady WM, Kinnard M, Willis J, Elston R, Eng C, Chak A. Consortium approach to identifying genes for Barrett's esophagus and esophageal adenocarcinoma. Translational Research : the Journal of Laboratory and Clinical Medicine. 150: 3-17. PMID 17585859 DOI: 10.1016/J.Trsl.2007.02.005  0.343
2007 Shete S, Elston RC, Lu Y. A novel approach to detect parent-of-origin effects from pedigree data with application to Beckwith-Wiedemann syndrome. Annals of Human Genetics. 71: 804-14. PMID 17578507 DOI: 10.1111/J.1469-1809.2007.00378.X  0.339
2007 Daley D, Morgan W, Lewis S, Willis J, Elston RC, Markowitz SD, Wiesner GL. Is TGFBR1*6A a susceptibility allele for nonsyndromic familial colorectal neoplasia? Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 16: 892-4. PMID 17507611 DOI: 10.1158/1055-9965.Epi-06-0965  0.572
2007 Elston RC, Lin D, Zheng G. Multistage sampling for genetic studies. Annual Review of Genomics and Human Genetics. 8: 327-42. PMID 17506660 DOI: 10.1146/Annurev.Genom.8.080706.092357  0.403
2007 Lou XY, Chen GB, Yan L, Ma JZ, Zhu J, Elston RC, Li MD. A generalized combinatorial approach for detecting gene-by-gene and gene-by-environment interactions with application to nicotine dependence American Journal of Human Genetics. 80: 1125-1137. PMID 17503330 DOI: 10.1086/518312  0.351
2007 Rybicki BA, Sinha R, Iyengar S, Gray-McGuire C, Elston RC, Iannuzzi MC. Genetic linkage analysis of sarcoidosis phenotypes: the sarcoidosis genetic analysis (SAGA) study. Genes and Immunity. 8: 379-86. PMID 17476268 DOI: 10.1038/Sj.Gene.6364396  0.728
2007 Clerget-Darpoux F, Elston RC. Are linkage analysis and the collection of family data dead? Prospects for family studies in the age of genome-wide association. Human Heredity. 64: 91-6. PMID 17476108 DOI: 10.1159/000101960  0.411
2007 Wang T, Zhu X, Elston RC. Improving power in contrasting linkage-disequilibrium patterns between cases and controls American Journal of Human Genetics. 80: 911-920. PMID 17436245 DOI: 10.1086/516794  0.41
2007 Stein CM, Zalwango S, Chiunda AB, Millard C, Leontiev DV, Horvath AL, Cartier KC, Chervenak K, Boom WH, Elston RC, Mugerwa RD, Whalen CC, Iyengar SK. Linkage and association analysis of candidate genes for TB and TNFalpha cytokine expression: evidence for association with IFNGR1, IL-10, and TNF receptor 1 genes. Human Genetics. 121: 663-73. PMID 17431682 DOI: 10.1007/S00439-007-0357-8  0.311
2007 Iyengar SK, Abboud HE, Goddard KA, Saad MF, Adler SG, Arar NH, Bowden DW, Duggirala R, Elston RC, Hanson RL, Ipp E, Kao WH, Kimmel PL, Klag MJ, Knowler WC, et al. Genome-wide scans for diabetic nephropathy and albuminuria in multiethnic populations: the family investigation of nephropathy and diabetes (FIND). Diabetes. 56: 1577-85. PMID 17363742 DOI: 10.2337/Db06-1154  0.318
2007 Zheng G, Song K, Elston RC. Adaptive two-stage analysis of genetic association in case-control designs. Human Heredity. 63: 175-86. PMID 17310127 DOI: 10.1159/000099830  0.574
2007 Wang T, Elston RC. Improved power by use of a weighted score test for linkage disequilibrium mapping American Journal of Human Genetics. 80: 353-360. PMID 17236140 DOI: 10.1086/511312  0.406
2007 Wang T, Elston RC. Regression-based multivariate linkage analysis with an application to blood pressure and body mass index Annals of Human Genetics. 71: 96-106. PMID 17227480 DOI: 10.1111/J.1469-1809.2006.00303.X  0.369
2007 Chung Y, Lee SY, Elston RC, Park T. Odds ratio based multifactor-dimensionality reduction method for detecting gene-gene interactions. Bioinformatics (Oxford, England). 23: 71-6. PMID 17092990 DOI: 10.1093/Bioinformatics/Btl557  0.337
2007 Beuten J, Ma JZ, Payne TJ, Dupont RT, Lou XY, Crews KM, Elston RC, Li MD. Association of Specific Haplotypes of Neurotrophic Tyrosine Kinase Receptor 2 Gene (NTRK2) with Vulnerability to Nicotine Dependence in African-Americans and European-Americans Biological Psychiatry. 61: 48-55. PMID 16713586 DOI: 10.1016/J.Biopsych.2006.02.023  0.308
2007 Bouzigon E, Guilloud-Bataille M, Oryszczyn M, Stefanadis C, Demenais F, Balise RR, Chen Y, Dite G, Felberg A, Sun L, Ziogas A, Whittemore AS, Zheng G, Francis PJ, George S, ... ... Elston RC, et al. Contents Vol. 63, 2007 Human Heredity. 63: 241-242. DOI: 10.1159/000101061  0.498
2007 Bouzigon E, Guilloud-Bataille M, Oryszczyn M, Stefanadis C, Demenais F, Balise RR, Chen Y, Dite G, Felberg A, Sun L, Ziogas A, Whittemore AS, Zheng G, Francis PJ, George S, ... ... Elston RC, et al. Subject Index Vol. 63, 2007 Human Heredity. 63: 240-240. DOI: 10.1159/000101060  0.507
2006 Mukhopadhyay I, Feingold E, Wang T, Elston RC, Weeks DE. Treatment of uninformative families in mean allele sharing tests for linkage. Statistical Applications in Genetics and Molecular Biology. 5: Article13. PMID 17049024 DOI: 10.2202/1544-6115.1206  0.377
2006 Chak A, Ochs-Balcom H, Falk G, Grady WM, Kinnard M, Willis JE, Elston R, Eng C. Familiality in Barrett's esophagus, adenocarcinoma of the esophagus, and adenocarcinoma of the gastroesophageal junction Cancer Epidemiology Biomarkers and Prevention. 15: 1668-1673. PMID 16985029 DOI: 10.1158/1055-9965.Epi-06-0293  0.324
2006 Judson MA, Hirst K, Iyengar SK, Rybicki BA, El-Ghormli L, Baughman RP, Donohue JF, Elston RC, Kavuru MS, Moller DR, Newman LS, Rabin DL, Rossman MD, Teirstein AS, Iannuzzi MC, et al. Comparison of sarcoidosis phenotypes among affected African-American siblings. Chest. 130: 855-62. PMID 16963686 DOI: 10.1378/Chest.130.3.855  0.314
2006 Li MD, Payne TJ, Ma JZ, Lou XY, Zhang D, Dupont RT, Crews KM, Somes G, Williams NJ, Elston RC. A genomewide search finds major susceptibility loci for nicotine dependence on chromosome 10 in African Americans American Journal of Human Genetics. 79: 745-751. PMID 16960812 DOI: 10.1086/508208  0.414
2006 Thompson CL, Rybicki BA, Iannuzzi MC, Elston RC, Iyengar SK, Gray-McGuire C. Reduction of sample heterogeneity through use of population substructure: an example from a population of African American families with sarcoidosis. American Journal of Human Genetics. 79: 606-13. PMID 16960797 DOI: 10.1086/507847  0.754
2006 Elston RC, Anne Spence M. Advances in statistical human genetics over the last 25 years. Statistics in Medicine. 25: 3049-80. PMID 16900576 DOI: 10.1002/Sim.2650  0.435
2006 Gray-McGuire C, Sinha R, Iyengar S, Millard C, Rybicki BA, Elston RC, Iannuzzi MC. Genetic characterization and fine mapping of susceptibility loci for sarcoidosis in African Americans on chromosome 5. Human Genetics. 120: 420-30. PMID 16896925 DOI: 10.1007/S00439-006-0201-6  0.73
2006 Xing C, Sinha R, Xing G, Lu Q, Elston RC. The affected-/discordant-sib-pair design can guarantee validity of multipoint model-free linkage analysis of incomplete pedigrees when there is marker-marker disequilibrium. American Journal of Human Genetics. 79: 396-401. PMID 16826532 DOI: 10.1086/506331  0.392
2006 Won S, Elston RC, Park T. Extension of the Haseman-Elston regression model to longitudinal data Human Heredity. 61: 111-119. PMID 16733364 DOI: 10.1159/000093519  0.369
2006 Li J, Zhou Y, Elston RC. Haplotype-based quantitative trait mapping using a clustering algorithm. Bmc Bioinformatics. 7: 258. PMID 16709248 DOI: 10.1186/1471-2105-7-258  0.362
2006 Xine C, Elston RC. Distribution and magnitude of type I error of model-based multipoint lod scores: Implications for multipoint mod scores Genetic Epidemiology. 30: 447-458. PMID 16685712 DOI: 10.1002/Gepi.20157  0.338
2006 Sinha M, Song Y, Elston RC, Olson JM, Goddard KA. Prediction of empirical p values from asymptotic p values for conditional logistic affected relative pair linkage analysis. Human Heredity. 61: 45-54. PMID 16612102 DOI: 10.1159/000092552  0.317
2006 Kaabi B, Gelernter J, Woods SW, Goddard A, Page GP, Elston RC. Genome scan for loci predisposing to anxiety disorders using a novel multivariate approach: strong evidence for a chromosome 4 risk locus. American Journal of Human Genetics. 78: 543-53. PMID 16532386 DOI: 10.1086/501072  0.737
2006 Wang T, Elston RC. A quantitative linkage score for an association study following a linkage analysis Bmc Genetics. 7. PMID 16426440 DOI: 10.1186/1471-2156-7-5  0.437
2006 Larkin EK, Patel SR, Redline S, Mignot E, Elston RC, Hallmayer J. Apolipoprotein E and obstructive sleep apnea: evaluating whether a candidate gene explains a linkage peak. Genetic Epidemiology. 30: 101-10. PMID 16374834 DOI: 10.1002/Gepi.20127  0.375
2006 Daw EW, Doan BQ, Elston RC. Linkage mapping methods applied to the COGA data set: presentation Group 4 of Genetic Analysis Workshop 14. Genetic Epidemiology. S29-34. PMID 16342182 DOI: 10.1002/Gepi.20107  0.406
2006 Song K, Elston RC. A powerful method of combining measures of association and Hardy-Weinberg disequilibrium for fine-mapping in case-control studies. Statistics in Medicine. 25: 105-26. PMID 16220513 DOI: 10.1002/Sim.2350  0.598
2006 Lou XY, Ma JZ, Yang MC, Zhu J, Liu PY, Deng HW, Elston RC, Li MD. Improvement of mapping accuracy by unifying linkage and association analysis. Genetics. 172: 647-61. PMID 16172505 DOI: 10.1534/Genetics.105.045781  0.434
2005 Song K, Orloff MS, Lu Q, Elston RC. Fine-mapping using the weighted average method for a case-control study. Bmc Genetics. 6: S67. PMID 16451680 DOI: 10.1186/1471-2156-6-S1-S67  0.63
2005 Jun G, Song Y, Iyengar SK, Elston RC. Optimizing the evidence for linkage by permuting marker order. Bmc Genetics. 6: S61. PMID 16451674 DOI: 10.1186/1471-2156-6-S1-S61  0.351
2005 Franke D, Kleensang A, Elston RC, Ziegler A. Haseman-Elston weighted by marker informativity. Bmc Genetics. S50. PMID 16451662 DOI: 10.1186/1471-2156-6-S1-S50  0.39
2005 Shih PY, Wang T, Xing C, Sinha M, Song Y, Elston RC. Linkage analysis of alcohol dependence using both affected and discordant sib pairs. Bmc Genetics. 6: S36. PMID 16451646 DOI: 10.1186/1471-2156-6-S1-S36  0.402
2005 Xing C, Schumacher FR, Xing G, Lu Q, Wang T, Elston RC. Comparison of microsatellites, single-nucleotide polymorphisms (SNPs) and composite markers derived from SNPs in linkage analysis. Bmc Genetics. S29. PMID 16451638 DOI: 10.1186/1471-2156-6-S1-S29  0.344
2005 Sinha R, Sinha M, Mathew G, Elston RC, Luo Y. Local false discovery rate and minimum total error rate approaches to identifying interesting chromosomal regions. Bmc Genetics. 6: S23. PMID 16451632 DOI: 10.1186/1471-2156-6-S1-S23  0.31
2005 Wang T, Elston RC. The bias introduced by population stratification in IBD based linkage analysis Human Heredity. 60: 134-142. PMID 16319490 DOI: 10.1159/000089867  0.431
2005 Stein CM, Nshuti L, Chiunda AB, Boom WH, Elston RC, Mugerwa RD, Iyengar SK, Whalen CC. Evidence for a major gene influence on tumor necrosis factor-alpha expression in tuberculosis: path and segregation analysis. Human Heredity. 60: 109-18. PMID 16224188 DOI: 10.1159/000088913  0.323
2005 Puranam RS, Jain S, Kleindienst AM, Saxena S, Kim MK, Kelly Changizi B, Padma MV, Andrews I, Elston RC, Tiwari HK, McNamara JO. A locus for generalized tonic-clonic seizure susceptibility maps to chromosome 10q25-q26. Annals of Neurology. 58: 449-58. PMID 16130088 DOI: 10.1002/Ana.20598  0.38
2005 Jun G, Klein BEK, Klein R, Fox K, Millard C, Capriotti J, Russo K, Lee KE, Elston RC, Iyengar SK. Genome-wide analyses demonstrate novel loci that predispose to drusen formation Investigative Ophthalmology and Visual Science. 46: 3081-3088. PMID 16123405 DOI: 10.1167/Iovs.04-1360  0.308
2005 Iannuzzi MC, Iyengar SK, Gray-McGuire C, Elston RC, Baughman RP, Donohue JF, Hirst K, Judson MA, Kavuru MS, Maliarik MJ, Moller DR, Newman LS, Rabin DL, Rose CS, Rossman MD, et al. Genome-wide search for sarcoidosis susceptibility genes in African Americans. Genes and Immunity. 6: 509-18. PMID 15951742 DOI: 10.1038/Sj.Gene.6364235  0.724
2005 Ma JZ, Beuten J, Payne TJ, Dupont RT, Elston RC, Li MD. Haplotype analysis indicates an association between the DOPA decarboxylase (DDC) gene and nicotine dependence Human Molecular Genetics. 14: 1691-1698. PMID 15879433 DOI: 10.1093/Hmg/Ddi177  0.33
2005 Wang T, Elston RC. Two-level Haseman-Elston regression for general pedigree data analysis Genetic Epidemiology. 29: 12-22. PMID 15838848 DOI: 10.1002/Gepi.20075  0.445
2005 Li MD, Beuten J, Ma JZ, Payne TJ, Lou XY, Garcia V, Duenes AS, Crews KM, Elston RC. Ethnic-and gender-specific association of the nicotinic acetylcholine receptor α4 subunit gene (CHRNA4) with nicotine dependence Human Molecular Genetics. 14: 1211-1219. PMID 15790597 DOI: 10.1093/Hmg/Ddi132  0.301
2005 Beuten J, Ma JZ, Payne TJ, Dupont RT, Crews KM, Somes G, Williams NJ, Elston RC, Li MD. Single- and multilocus allelic variants within the GABAB receptor subunit 2 (GABAB2) gene are significantly associated with nicotine dependence American Journal of Human Genetics. 76: 859-864. PMID 15759211 DOI: 10.1086/429839  0.328
2005 Bukulmez H, Fife M, Tsoras M, Thompson SD, Twine NA, Woo P, Olson JM, Elston RC, Glass DN, Colbert RA. Tapasin gene polymorphism in systemic onset juvenile rheumatoid arthritis: a family-based case-control study. Arthritis Research & Therapy. 7: R285-90. PMID 15743475 DOI: 10.1186/Ar1480  0.427
2005 Knowler WC, Coresh J, Elston RC, Freedman BI, Iyengar SK, Kimmel PL, Olson JM, Plaetke R, Sedor JR, Seldin MF. The Family Investigation of Nephropathy and Diabetes (FIND): design and methods. Journal of Diabetes and Its Complications. 19: 1-9. PMID 15642484 DOI: 10.1016/J.Jdiacomp.2003.12.007  0.327
2005 Cheng R, Ma JZ, Elston RC, Li MD. Fine mapping functional sites or regions from case-control data using haplotypes of multiple linked SNPs Annals of Human Genetics. 69: 102-112. PMID 15638831 DOI: 10.1046/J.1529-8817.2004.00140.X  0.362
2005 Larkin EK, Elston RC, Patel SR, Tishler PV, Palmer LJ, Jenny NS, Redline S. Linkage of serum leptin levels in families with sleep apnea. International Journal of Obesity (2005). 29: 260-7. PMID 15611783 DOI: 10.1038/Sj.Ijo.0802872  0.382
2005 Elston RC, Song D, Iyengar SK. Mathematical assumptions versus biological reality: Myths in affected sib pair linkage analysis American Journal of Human Genetics. 76: 152-156. PMID 15540158 DOI: 10.1086/426872  0.387
2004 Elston RC, Gray-McGuire C. A review of the 'Statistical Analysis for Genetic Epidemiology' (S.A.G.E.) software package. Human Genomics. 1: 456-9. PMID 15607000 DOI: 10.1186/1479-7364-1-6-456  0.7
2004 Beall CM, Song K, Elston RC, Goldstein MC. Higher offspring survival among Tibetan women with high oxygen saturation genotypes residing at 4,000 m. Proceedings of the National Academy of Sciences of the United States of America. 101: 14300-4. PMID 15353580 DOI: 10.1073/Pnas.0405949101  0.535
2004 Ginsburg E, Malkin I, Elston RC. Sampling correction in linkage analysis Genetic Epidemiology. 27: 87-96. PMID 15305325 DOI: 10.1002/Gepi.20008  0.31
2004 Zhu X, Cooper RS, Elston RC. Linkage analysis of a complex disease through use of admixed populations American Journal of Human Genetics. 74: 1136-1153. PMID 15131754 DOI: 10.1086/421329  0.395
2004 Palmer LJ, Buxbaum SG, Larkin EK, Patel SR, Elston RC, Tishler PV, Redline S. Whole genome scan for obstructive sleep apnea and obesity in African-American families. American Journal of Respiratory and Critical Care Medicine. 169: 1314-21. PMID 15070816 DOI: 10.1164/Rccm.200304-493Oc  0.682
2004 Stein CM, Schick JH, Taylor HG, Shriberg LD, Millard C, Kundtz-Kluge A, Russo K, Minich N, Hansen A, Freebairn LA, Elston RC, Lewis BA, Iyengar SK. Pleiotropic Effects of a Chromosome 3 Locus on Speech-Sound Disorder and Reading American Journal of Human Genetics. 74: 283-297. PMID 14740317 DOI: 10.1086/381562  0.354
2004 Wang Q, Rao S, Shen GQ, Li L, Moliterno DJ, Newby LK, Rogers WJ, Cannata R, Zirzow E, Elston RC, Topol EJ. Premature myocardial infarction novel susceptibility locus on chromosome 1P34-36 identified by genomewide linkage analysis. American Journal of Human Genetics. 74: 262-71. PMID 14732905 DOI: 10.1086/381560  0.423
2004 Iyengar SK, Song D, Klein BE, Klein R, Schick JH, Humphrey J, Millard C, Liptak R, Russo K, Jun G, Lee KE, Fijal B, Elston RC. Dissection of genomewide-scan data in extended families reveals a major locus and oligogenic susceptibility for age-related macular degeneration. American Journal of Human Genetics. 74: 20-39. PMID 14691731 DOI: 10.1086/380912  0.309
2004 Wiener H, Elston RC, Tiwari HK. X-linked extension of the revised Haseman-Elston algorithm for linkage analysis in sib pairs. Human Heredity. 55: 97-107. PMID 12931048 DOI: 10.1159/000072314  0.376
2004 Schaid DJ, Olson JM, Gauderman WJ, Elston RC. Regression models for linkage: issues of traits, covariates, heterogeneity, and interaction. Human Heredity. 55: 86-96. PMID 12931047 DOI: 10.1159/000072313  0.398
2004 Shete S, Jacobs KB, Elston RC. Adding further power to the Haseman and Elston method for detecting linkage in larger sibships: weighting sums and differences. Human Heredity. 55: 79-85. PMID 12931046 DOI: 10.1159/000072312  0.374
2004 Elston RC, Gray-McGuire C. A review of the 'Statistical Analysis for Genetic Epidemiology' (SAGE) software package Human Genomics. DOI: 10.1186/1479-7364-1-6-456  0.683
2004 Elston RC, Goddard KA. Jane M. Olson (December 6, 1952–May 2, 2004) The American Journal of Human Genetics. 75: 159-160. DOI: 10.1086/423149  0.353
2003 Ginsburg E, Malkin I, Elston RC. Sampling correction in pedigree analysis. Statistical Applications in Genetics and Molecular Biology. 2: Article2. PMID 16646780 DOI: 10.2202/1544-6115.1003  0.322
2003 Ma JZ, Zhang D, Dupont RT, Dockter M, Elston RC, Li MD. Mapping susceptibility loci for alcohol consumption using number of grams of alcohol consumed per day as a phenotype measure Bmc Genetics. 4. PMID 14975172 DOI: 10.1186/1471-2156-4-S1-S104  0.339
2003 Li MD, Ma JZ, Cheng R, Dupont RT, Williams NJ, Crews KM, Payne TJ, Elston RC, Framingham Heart Study. A genome-wide scan to identify loci for smoking rate in the Framingham Heart Study population Bmc Genetics. 4. PMID 14975171 DOI: 10.1186/1471-2156-4-S1-S103  0.37
2003 Jacobs KB, Gray-McGuire C, Cartier KC, Elston RC. Genome-wide linkage scan for genes affecting longitudinal trends in systolic blood pressure. Bmc Genetics. 4: S82. PMID 14975150 DOI: 10.1186/1471-2156-4-S1-S82  0.709
2003 Song K, Elston RC. Tests for a disease-susceptibility locus allowing for an inbreeding coefficient (F). Genetica. 119: 269-81. PMID 14686606 DOI: 10.1023/B:Gene.0000003681.02766.3C  0.567
2003 Wiesner GL, Daley D, Lewis S, Ticknor C, Platzer P, Lutterbaugh J, MacMillen M, Baliner B, Willis J, Elston RC, Markowitz SD. A subset of familial colorectal neoplasia kindreds linked to chromosome 9q22.2-31.2. Proceedings of the National Academy of Sciences of the United States of America. 100: 12961-5. PMID 14566058 DOI: 10.1073/Pnas.2132286100  0.585
2003 Keen KJ, Elston RC. Robust asymptotic sampling theory for correlations in pedigrees Statistics in Medicine. 22: 3229-3247. PMID 14518025 DOI: 10.1002/Sim.1559  0.394
2003 Satagopan JM, Elston RC. Optimal two-stage genotyping in population-based association studies Genetic Epidemiology. 25: 149-157. PMID 12916023 DOI: 10.1002/Gepi.10260  0.302
2003 Zabetian CP, Buxbaum SG, Elston RC, Köhnke MD, Anderson GM, Gelernter J, Cubells JF. The structure of linkage disequilibrium at the DBH locus strongly influences the magnitude of association between diallelic markers and plasma dopamine beta-hydroxylase activity. American Journal of Human Genetics. 72: 1389-400. PMID 12730829 DOI: 10.1086/375499  0.697
2003 Schick JH, Iyengar SK, Klein BE, Klein R, Reading K, Liptak R, Millard C, Lee KE, Tomany SC, Moore EL, Fijal BA, Elston RC. A whole-genome screen of a quantitative trait of age-related maculopathy in sibships from the Beaver Dam Eye Study. American Journal of Human Genetics. 72: 1412-24. PMID 12717633 DOI: 10.1016/J.Ajo.2003.08.024  0.373
2003 Kaabi B, Elston RC. New multivariate test for linkage, with application to pleiotropy: fuzzy Haseman-Elston. Genetic Epidemiology. 24: 253-64. PMID 12687642 DOI: 10.1002/Gepi.10234  0.721
2003 Gass JR, Valiathan M, Tiwari HK, Hans MG, Elston RC. Familial correlations and heritability of maxillary midline diastema. American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics. 123: 35-9. PMID 12532061 DOI: 10.1067/Mod.2003.56  0.362
2003 Palmer LJ, Buxbaum SG, Larkin E, Patel SR, Elston RC, Tishler PV, Redline S. A whole-genome scan for obstructive sleep apnea and obesity. American Journal of Human Genetics. 72: 340-50. PMID 12506338 DOI: 10.1086/346064  0.677
2002 Rybicki BA, Iyengar SK, Harris T, Liptak R, Elston RC, Sheffer R, Chen KM, Major M, Maliarik MJ, Iannuzzi MC. The distribution of long range admixture linkage disequilibrium in an African-American population Human Heredity. 53: 187-196. PMID 12435883 DOI: 10.1159/000066193  0.388
2002 Malkin I, Ginsburg E, Elston RC. Increase in power of transmission-disequilibrium tests for quantitative traits Genetic Epidemiology. 23: 234-244. PMID 12384976 DOI: 10.1002/Gepi.10180  0.368
2002 Buxbaum SG, Elston RC, Tishler PV, Redline S. Genetics of the apnea hypopnea index in Caucasians and African Americans: I. Segregation analysis. Genetic Epidemiology. 22: 243-53. PMID 11921084 DOI: 10.1002/Gepi.0170  0.686
2002 Guo X, Olson JM, Elston RC, Niu T. The linkage information content value of polymorphism genetic markers in model-free linkage analysis. Human Heredity. 53: 45-8. PMID 11901271 DOI: 10.1159/000048604  0.343
2002 Zhu X, Cooper RS, Chen G, Luke A, Elston RC. Localization of the Q1 mutation by cladistic analysis. Genetic Epidemiology. S594-9. PMID 11793744 DOI: 10.1002/Gepi.2001.21.S1.S594  0.333
2002 Schnell AH, Palmer LJ, Elston RC. Segregation analysis of asthma and respiratory allergy in population-based samples of families. Genetic Epidemiology. S30-5. PMID 11793687 DOI: 10.1002/Gepi.2001.21.S1.S30  0.312
2001 Amos CI, Schnell A, Chen WV, Elston RC. UNIT 1.8 Model-Free Tests for Genetic Linkage Current Protocols in Human Genetics. PMID 18428238 DOI: 10.1002/0471142905.Hg0108S28  0.392
2001 Mosley J, Conti DV, Elston RC, Witte JS. Impact of preadjusting a quantitative phenotype prior to sib-pair linkage analysis when gene x environment interaction exists Genetic Epidemiology. 21. PMID 11793789 DOI: 10.1002/Gepi.2001.21.S1.S837  0.333
2001 Cheng R, Ma JZ, Elston RC, Li MD. Comparison of marker intervals and number of sib pairs used for linkage analysis on simulated nuclear family data Genetic Epidemiology. 21. PMID 11793772 DOI: 10.1002/Gepi.2001.21.S1.S748  0.366
2001 Jacobs KB, Burton PR, Iyengar SK, Elston RC, Palmer LJ. Pooling data and linkage analysis in the chromosome 5q candidate region for asthma Genetic Epidemiology. 21. PMID 11793650 DOI: 10.1002/Gepi.2001.21.S1.S103  0.419
2001 Silverman EK, Mosley JD, Rao DC, Palmer LJ, Province MA, Elston RC, Weiss ST, Campbell EJ. Linkage analysis of alpha 1-antitrypsin deficiency: lessons for complex diseases. Human Heredity. 52: 223-32. PMID 11713419 DOI: 10.1159/000053380  0.37
2001 Kaufman ES, Priori SG, Napolitano C, Schwartz PJ, Iyengar S, Elston RC, Schnell AH, Gorodeski EZ, Rammohan G, Bahhur NO, Connuck D, Verrilli L, Rosenbaum DS, Brown AM. Electrocardiographic prediction of abnormal genotype in congenital long QT syndrome: experience in 101 related family members. Journal of Cardiovascular Electrophysiology. 12: 455-61. PMID 11332568 DOI: 10.1046/J.1540-8167.2001.00455.X  0.377
2001 Wiesner GL, Platzer P, Buxbaum S, Lewis S, MacMillen M, Olechnowicz J, Willis J, Chakravarti A, Elston RC, Markowitz SD. Testing for Colon Neoplasia Susceptibility Variants at the Human COX2 Locus Journal of the National Cancer Institute. 93: 635-639. PMID 11309440 DOI: 10.1093/Jnci/93.8.635  0.682
2001 Zhu X, Elston RC, Cooper RS. Testing quantitative traits for association and linkage in the presence or absence of parental data Human Heredity. 51: 183-191. PMID 11287739 DOI: 10.1159/000053341  0.375
2001 Zhu X, Bouzekri N, Southam L, Cooper RS, Adeyemo A, McKenzie CA, Luke A, Chen G, Elston RC, Ward R. Linkage and association analysis of angiotensin I-converting enzyme (ACE)-gene polymorphisms with ACE concentration and blood pressure. American Journal of Human Genetics. 68: 1139-48. PMID 11283791 DOI: 10.1086/320104  0.374
2001 Zabetian CP, Anderson GM, Buxbaum SG, Elston RC, Ichinose H, Nagatsu T, Kim KS, Kim CH, Malison RT, Gelernter J, Cubells JF. A quantitative-trait analysis of human plasma-dopamine beta-hydroxylase activity: evidence for a major functional polymorphism at the DBH locus. American Journal of Human Genetics. 68: 515-22. PMID 11170900 DOI: 10.1086/318198  0.642
2001 Palmer LJ, Jacobs KB, Elston RC. Haseman and Elston revisited: the effects of ascertainment and residual familial correlations on power to detect linkage. Genetic Epidemiology. 19: 456-60. PMID 11108653 DOI: 10.1002/1098-2272(200012)19:4<456::Aid-Gepi15>3.0.Co;2-N  0.313
2001 Guo X, Elston RC. 27 One-stage versus two-stage strategies for genome scans Advances in Genetics. 42: 459-471. PMID 11037335 DOI: 10.1016/S0065-2660(01)42036-0  0.377
2001 Elston RC, Cordell HJ. 11 Overview of model-free methods for linkage analysis Advances in Genetics. 42: 135-150. PMID 11037319 DOI: 10.1016/S0065-2660(01)42020-7  0.413
2001 Schick JH, Iyengar SK, Elston RC, Fijal BA, Klein BE, Klein R. The Genetic Epidemiology of Age-Related Maculopathy International Journal of Human Genetics. 1: 11-24. DOI: 10.31901/24566330.2001/01.01.02  0.307
2001 Keen KJ, Elston RC. A problem in ascertainment Communications in Statistics - Theory and Methods. 30: 1615-1631. DOI: 10.1081/Sta-100105688  0.34
2000 Elston RC. Introduction and overview Statistical Methods in Medical Research. 9: 527-541. PMID 11308069 DOI: 10.1191/096228000666851885  0.327
2000 Elston RC, Thompson EA. A century of biometrical genetics Biometrics. 56: 659-666. PMID 10985200 DOI: 10.1111/J.0006-341X.2000.00659.X  0.382
2000 Schaid DJ, Elston RC, Tran L, Wilson AF. Model-free sib-pair linkage analysis: Combining full-sib and half-sib pairs Genetic Epidemiology. 19: 30-51. PMID 10861895 DOI: 10.1002/1098-2272(200007)19:1<30::Aid-Gepi3>3.0.Co;2-X  0.393
2000 Elston RC, Buxbaum S, Jacobs KB, Olson JM. Haseman and Elston revisited. Genetic Epidemiology. 19: 1-17. PMID 10861893 DOI: 10.1002/1098-2272(200007)19:1<1::Aid-Gepi1>3.0.Co;2-E  0.679
2000 Shete S, Tiwari H, Elston RC. On estimating the heterozygosity and polymorphism information content value Theoretical Population Biology. 57: 265-271. PMID 10828218 DOI: 10.1006/Tpbi.2000.1452  0.331
2000 Witte JS, Goddard KA, Conti DV, Elston RC, Lin J, Suarez BK, Broman KW, Burmester JK, Weber JL, Catalona WJ. Genomewide scan for prostate cancer-aggressiveness loci. American Journal of Human Genetics. 67: 92-9. PMID 10825281 DOI: 10.1086/302960  0.394
2000 Schnell AH, Elston RC, Hull PR, Lane PR. Major gene segregation of actinic prurigo among North American Indians in Saskatchewan. American Journal of Medical Genetics. 92: 212-9. PMID 10817657 DOI: 10.1002/(Sici)1096-8628(20000529)92:3<212::Aid-Ajmg10>3.0.Co;2-W  0.318
2000 Mandal DM, Wilson AF, Elston RC, Weissbecker K, Keats BJ, Bailey-Wilson JE. Effects of misspecification of allele frequencies on the type I error rate of model-free linkage analysis Human Heredity. 50: 126-132. PMID 10799971 DOI: 10.1159/000022900  0.356
2000 Zhu X, Elston RC. Power comparison of regression methods to test quantitative traits for association and linkage Genetic Epidemiology. 18: 322-330. PMID 10797592 DOI: 10.1002/(Sici)1098-2272(200004)18:4<322::Aid-Gepi5>3.0.Co;2-#  0.373
2000 Guo X, Rotimi C, Cooper R, Luke A, Elston RC, Ogunbiyi O, Ward R. Evidence of a major gene effect for angiotensinogen among Nigerians. Annals of Human Genetics. 63: 293-300. PMID 10738541 DOI: 10.1046/J.1469-1809.1999.6340293.X  0.363
2000 Cordell HJ, Wedig GC, Jacobs KB, Elston RC. Multilocus linkage tests based on affected relative pairs. American Journal of Human Genetics. 66: 1273-86. PMID 10729111 DOI: 10.1086/302847  0.401
2000 Suarez BK, Lin J, Burmester JK, Broman KW, Weber JL, Banerjee TK, Goddard KA, Witte JS, Elston RC, Catalona WJ. A genome screen of multiplex sibships with prostate cancer. American Journal of Human Genetics. 66: 933-44. PMID 10712208 DOI: 10.1086/302818  0.37
2000 Rybicki BA, Elston RC. The relationship between the sibling recurrence-risk ratio and genotype relative risk American Journal of Human Genetics. 66: 593-604. PMID 10677319 DOI: 10.1086/302778  0.366
2000 Guo X, Elston RC. Two-stage global search designs for linkage analysis II: Including discordant relative pairs in the study Genetic Epidemiology. 18: 111-127. PMID 10642425 DOI: 10.1002/(Sici)1098-2272(200002)18:2<111::Aid-Gepi2>3.0.Co;2-M  0.314
2000 Guo X, Elston RC. Two-stage global search designs for linkage analysis I: Use of the mean statistic for affected sib pairs Genetic Epidemiology. 18: 97-110. PMID 10642424 DOI: 10.1002/(Sici)1098-2272(200002)18:2<97::Aid-Gepi1>3.0.Co;2-J  0.371
2000 Cordell HJ, Jacobs KB, Wedig GC, Elston RC. Improving the power for disease locus detection in affected-sib-pair studies by using two-locus analysis and multiple regression methods. Genetic Epidemiology. S521-6. PMID 10597486 DOI: 10.1002/Gepi.1370170784  0.404
2000 Tiwari HK, Zhu X, Elston RC, Shu Y, George V. Association and linkage analysis of ICD-10 diagnosis for alcoholism. Genetic Epidemiology. S343-7. PMID 10597460 DOI: 10.1002/Gepi.1370170758  0.379
2000 Olson JM, Rao S, Jacobs K, Elston RC. Linkage of chromosome 1 markers to alcoholism-related phenotypes by sib pair linkage analysis of principal components. Genetic Epidemiology. S271-6. PMID 10597448 DOI: 10.1002/Gepi.1370170746  0.379
2000 Jacobs KB, Wedig GC, Schnell AH, Witte JS, Elston RC. Model-based and model-free multipoint genome-wide linkage analysis of alcoholism. Genetic Epidemiology. S175-80. PMID 10597432 DOI: 10.1002/Gepi.1370170730  0.383
2000 George V, Tiwari HK, Shu Y, Zhu X, Elston RC. Linkage and association analyses of alcoholism using a regression-based transmission/disequilibrium test. Genetic Epidemiology. S157-61. PMID 10597429 DOI: 10.1002/Gepi.1370170727  0.398
2000 Elston RC, Shete SS. Adding power to Haseman and Elston's (1972) method Genescreen. 1: 63-64. DOI: 10.1046/J.1466-9218.2000.00028.X  0.389
1999 Cordell HJ, Elston RC. Fieller's theorem and linkage disequilibrium mapping Genetic Epidemiology. 17: 237-252. PMID 10520208 DOI: 10.1002/(Sici)1098-2272(199911)17:4<237::Aid-Gepi1>3.0.Co;2-P  0.39
1999 Zheng C, Elston RC. Multipoint linkage disequilibrium mapping with particular reference disequilibrium mapping with particular reference to the African-American population Genetic Epidemiology. 17: 79-101. PMID 10414554 DOI: 10.1002/(Sici)1098-2272(1999)17:2<79::Aid-Gepi1>3.0.Co;2-N  0.352
1999 George V, Tiwari HK, Zhu X, Elston RC. A test of transmission/disequilibrium for quantitative traits in pedigree data, by multiple regression. American Journal of Human Genetics. 65: 236-45. PMID 10364537 DOI: 10.1086/302444  0.421
1999 Guo X, Elston RC. Linkage information content of polymorphic genetic markers Human Heredity. 49: 112-118. PMID 10077733 DOI: 10.1159/000022855  0.334
1998 Ginns EI, St Jean P, Philibert RA, Galdzicka M, Damschroder-Williams P, Thiel B, Long RT, Ingraham LJ, Dalwaldi H, Murray MA, Ehlert M, Paul S, Remortel BG, Patel AP, Anderson MC, ... ... Elston RC, et al. A genome-wide search for chromosomal loci linked to mental health wellness in relatives at high risk for bipolar affective disorder among the Old Order Amish. Proceedings of the National Academy of Sciences of the United States of America. 95: 15531-6. PMID 9861003 DOI: 10.1073/Pnas.95.26.15531  0.36
1998 Allison DB, Thiel B, St Jean P, Elston RC, Infante MC, Schork NJ. Multiple phenotype modeling in gene-mapping studies of quantitative traits: power advantages. American Journal of Human Genetics. 63: 1190-201. PMID 9758596 DOI: 10.1086/302038  0.398
1998 Tiwari HK, Elston RC. Restrictions on components of variance for epistatic models Theoretical Population Biology. 54: 161-174. PMID 9733657 DOI: 10.1006/Tpbi.1997.1373  0.365
1998 Drigalenko E, Poduslo S, Elston RC. Interaction of the apolipoprotein E and CI loci in predisposing to late-onset Alzheimer's disease Neurology. 51: 131-135. PMID 9674791 DOI: 10.1212/Wnl.51.1.131  0.329
1998 Karunaratne PM, Elston RC. A multivariate logistic model (MLM) for analyzing binary family data American Journal of Medical Genetics. 76: 428-437. PMID 9556304 DOI: 10.1002/(Sici)1096-8628(19980413)76:5<428::Aid-Ajmg12>3.0.Co;2-O  0.329
1998 Karunaratne PM, Elston RC, Loman N, Olsson H, Ranstam J. Analysis of Swedish male breast cancer family data: a simple way to incorporate a common sibling effect. Genetic Epidemiology. 15: 201-12. PMID 9554557 DOI: 10.1002/(Sici)1098-2272(1998)15:2<201::Aid-Gepi8>3.0.Co;2-8  0.329
1998 Olson JM, Elston RC. Using family history information to distinguish true and false positive model-free linkage results. Genetic Epidemiology. 15: 183-92. PMID 9554555 DOI: 10.1002/(Sici)1098-2272(1998)15:2<183::Aid-Gepi6>3.0.Co;2-7  0.412
1998 Allison DB, Heo M, Schork NJ, Wong SL, Elston RC. Extreme selection strategies in gene mapping studies of oligogenic quantitative traits do not always increase power Human Heredity. 48: 97-107. PMID 9526169 DOI: 10.1159/000022788  0.385
1998 Zhu X, Olson JM, Schnell AH, Elston RC. Model-free age-of-onset methods applied to the linkage of bipolar disorder. Genetic Epidemiology. 14: 711-6. PMID 9433568 DOI: 10.1002/(Sici)1098-2272(1997)14:6<711::Aid-Gepi27>3.0.Co;2-S  0.361
1998 Schnell AH, Karunaratne PM, Witte JS, Dawson DV, Elston RC. Modeling age of onset and residual familial correlations for the linkage analysis of bipolar disorder. Genetic Epidemiology. 14: 675-80. PMID 9433562 DOI: 10.1002/(Sici)1098-2272(1997)14:6<675::Aid-Gepi21>3.0.Co;2-M  0.379
1998 Cleves MA, Dawson DV, Elston RC, Schnell AH. A new test statistic for linkage applied to bipolar disorder and marker D18S41. Genetic Epidemiology. 14: 581-6. PMID 9433546 DOI: 10.1002/(Sici)1098-2272(1997)14:6<581::Aid-Gepi5>3.0.Co;2-2  0.36
1997 Tiwari HK, Elston RC. Deriving components of genetic variance for multilocus models Genetic Epidemiology. 14: 1131-1136. PMID 9433636 DOI: 10.1002/(Sici)1098-2272(1997)14:6<1131::Aid-Gepi95>3.0.Co;2-H  0.339
1997 Todorov AA, Siegmund KD, Gu C, Borecki IB, Elston RC. Probabilities of identity-by-descent patterns in sibships when the parents are not genotyped. Genetic Epidemiology. 14: 909-13. PMID 9433599 DOI: 10.1002/(Sici)1098-2272(1997)14:6<909::Aid-Gepi58>3.0.Co;2-Q  0.302
1997 Drigalenko EI, Elston RC. False discoveries in genome scanning Genetic Epidemiology. 14: 779-784. PMID 9433577 DOI: 10.1002/(Sici)1098-2272(1997)14:6<779::Aid-Gepi36>3.0.Co;2-L  0.319
1997 Zhao LP, Hsu L, Davidov O, Potter J, Elston RC, Prentice RL. Population-based family study designs: An interdisciplinary research framework for genetic epidemiology Genetic Epidemiology. 14: 365-388. PMID 9271710 DOI: 10.1002/(Sici)1098-2272(1997)14:4<365::Aid-Gepi3>3.0.Co;2-2  0.424
1997 Tiwari HK, Elston RC. Linkage of multilocus components of variance to polymorphic markers Annals of Human Genetics. 61: 253-261. PMID 9250354 DOI: 10.1046/J.1469-1809.1997.6130253.X  0.428
1997 Olson JM, Witte JS, Elston RC. Association within twin pairs for a dichotomous trait. Genetic Epidemiology. 13: 489-99. PMID 8905395 DOI: 10.1002/(Sici)1098-2272(1996)13:5<489::Aid-Gepi5>3.0.Co;2-Y  0.346
1996 Elston RC, Guo X, Williams LV. Two-stage global search designs for linkage analysis using pairs of affected relatives Genetic Epidemiology. 13: 535-558. PMID 8968713 DOI: 10.1002/(Sici)1098-2272(1996)13:6<535::Aid-Gepi2>3.0.Co;2-#  0.344
1996 Zhong F, McCombs CC, Olson JM, Elston RC, Stevens FM, McCarthy CF, Michalski JP. An autosomal screen for genes that predispose to celiac disease in the western counties of Ireland. Nature Genetics. 14: 329-333. PMID 8896565 DOI: 10.1038/Ng1196-329  0.372
1996 Singh AD, Wang MX, Donoso LA, Shields CL, Potter PD, Shields JA, Elston RC, Fijal B. Familial uveal melanoma, III. Is the occurrence of familial uveal melanoma coincidental?. Archives of Ophthalmology (Chicago, Ill. : 1960). 114: 1101-4. PMID 8790096 DOI: 10.1001/Archopht.1996.01100140303008  0.32
1996 Holberg CJ, Elston RC, Halonen M, Wright AL, Taussig LM, Morgan WJ, Martinez FD. Segregation analysis of physician-diagnosed asthma in Hispanic and non-Hispanic white families. A recessive component? American Journal of Respiratory and Critical Care Medicine. 154: 144-50. PMID 8680670 DOI: 10.1164/Ajrccm.154.1.8680670  0.318
1995 Elston RC. Linkage and association to genetic markers Experimental and Clinical Immunogenetics. 12: 129-140. PMID 8534500 DOI: 10.1002/(SICI)1098-2272(1998)15:6<565::AID-GEPI2>3.0.CO;2-J  0.307
1995 Arai T, Michalski JP, McCombs CC, Elston RC, McCarthy CF, Stevens FM. T cell receptor gamma gene polymorphisms and class II human lymphocyte antigen genotypes in patients with celiac disease from the west of Ireland. The American Journal of the Medical Sciences. 309: 171-8. PMID 7879822 DOI: 10.1097/00000441-199503000-00008  0.303
1995 Nick TG, George V, Elston RC, Wilson AF. Statistical validity for testing associations between genetic markers and quantitative traits in family data Genetic Epidemiology. 12: 145-161. PMID 7607415 DOI: 10.1002/Gepi.1370120204  0.326
1994 Schaid DJ, Elston RC. Combining two-point genetic linkage analyses using mapping functions Genetic Epidemiology. 11: 1-17. PMID 8013885 DOI: 10.1002/Gepi.1370110102  0.385
1990 Amos CI, Dawson DV, Elston RC. The probabilistic determination of identity-by-descent sharing for pairs of relatives from pedigrees American Journal of Human Genetics. 47: 842-853. PMID 2220824  0.301
1989 McGue M, Wette R, Rao DC, Elston RC. Path analysis under generalized marital resemblance: evaluation of the assumptions underlying the mixed homogamy model by the Monte Carlo method. Genetic Epidemiology. 6: 373-388. PMID 2721930 DOI: 10.1002/Gepi.1370060207  0.418
1989 Amos CI, Elston RC. Robust methods for the detection of genetic linkage for quantitative data from pedigrees Genetic Epidemiology. 6: 349-360. PMID 2721929  0.302
1989 Cox N, Reich T, Rice J, Elston R, Schober J, Keats B. Segregation and linkage analyses of bipolar and major depressive illnesses in multigenerational pedigrees Journal of Psychiatric Research. 23: 109-123. PMID 2585343 DOI: 10.1016/0022-3956(89)90002-2  0.319
1987 George VT, Elston RC. Testing the association between polymorphic markers and quantitative traits in pedigrees Genetic Epidemiology. 4: 193-201. PMID 3609719  0.313
1987 Sellers TA, Ooi WL, Elston RC, Chen VW, Bailey-Wilson JE, Rothschild H. Increased familial risk for non-lung cancer among relatives of lung cancer patients. American Journal of Epidemiology. 126: 237-46. PMID 3605052 DOI: 10.1093/Aje/126.2.237  0.305
1986 Townley RG, Bewtra A, Wilson AF, Hopp RJ, Elston RC, Nair N, Watt GD. Segregation analysis of bronchial response to methacholine inhalation challenge in families with and without asthma The Journal of Allergy and Clinical Immunology. 77: 101-107. PMID 3944368 DOI: 10.1016/0091-6749(86)90330-1  0.302
1985 Pericak-Vance MA, Vance JM, Elston RC, Namboodiri KK, Fogle TA. Segregation and linkage analysis of α-N-acetyl-D-glucosaminidase (NAG) levels in a black family American Journal of Medical Genetics. 20: 295-306. PMID 3976723 DOI: 10.1002/Ajmg.1320200213  0.312
1984 Wilson AF, Elston RC, Siervogel RM, Weinshilboum R, Ward LJ. Linkage relationships between a major gene for catechol-O-methyltransferase activity and 25 polymorphic marker systems American Journal of Medical Genetics. 19: 525-532. PMID 6507499 DOI: 10.1002/Ajmg.1320190314  0.306
1983 King MC, Go RC, Lynch HT, Elston RC, Terasaki PI, Petrakis NL, Rodgers GC, Lattanzio D, Bailey-Wilson J. Genetic epidemiology of breast cancer and associated cancers in high-risk families. II. Linkage analysis. Journal of the National Cancer Institute. 71: 463-7. PMID 6577221 DOI: 10.1093/Jnci/71.3.463  0.358
1983 Go RCP, King M, Bailey-Wilson J, Elston RC, Lynch HT. Genetic Epidemiology of Breast Cancer and Associated Cancers in High-Risk Families. I. Segregation Analysis Journal of the National Cancer Institute. 71: 455-461. DOI: 10.1093/Jnci/71.3.455  0.307
1982 Elston RC, Cannings C, Thompson EA. Genealogical and Genetic Structure. Biometrics. 38: 1128. DOI: 10.2307/2529911  0.31
1981 Goldin LR, Elston RC, Graham JB, Miller CH. Genetic analysis of von Willebrand's disease in two large pedigrees: a multivariate approach. American Journal of Medical Genetics. 6: 279-93. PMID 6782878 DOI: 10.1002/ajmg.1320060405  0.321
1980 Fogle TA, Namboodiri KK, Elston RC, McKenzie WH, Hames CG. Linkage relationships of biochemical markers to Q- and C-band variants in a large black kindred. Human Genetics. 55: 353-6. PMID 6937430 DOI: 10.1007/Bf00290217  0.363
1979 Elston RC. Major locus analysis for quantitative traits American Journal of Human Genetics. 31: 655-660. PMID 517517  0.348
1979 Boyle CR, Elston RC. Multifactorial genetic models for quantitative traits in humans Biometrics. 35: 55-68. PMID 497338  0.306
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