Arlan Richardson - Publications

Affiliations: 
The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States 
Area:
Animal Physiology Biology, Biostatistics Biology
Website:
http://www.ouhsc.edu/roca/OurPeople/ProfilePage/TabId/11561/ArtMID/30320/ArticleID/2185/ARLAN-RICHARDSON-PHD.aspx

166 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Unnikrishnan A, Kurup K, Salmon AB, Richardson A. Is Rapamycin a Dietary Restriction Mimetic? The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 30854544 DOI: 10.1093/gerona/glz060  0.68
2019 Ahn B, Ranjit R, Premkumar P, Pharaoh G, Piekarz KM, Matsuzaki S, Claflin DR, Riddle K, Judge J, Bhaskaran S, Satara Natarajan K, Barboza E, Wronowski B, Kinter M, Humphries KM, ... ... Richardson A, et al. Mitochondrial oxidative stress impairs contractile function but paradoxically increases muscle mass via fibre branching. Journal of Cachexia, Sarcopenia and Muscle. PMID 30706998 DOI: 10.1002/jcsm.12375  0.72
2019 Deepa SS, Van Remmen H, Brooks SV, Faulkner JA, Larkin L, McArdle A, Jackson MJ, Vasilaki A, Richardson A. Accelerated sarcopenia in Cu/Zn superoxide dismutase knockout mice. Free Radical Biology & Medicine. 132: 19-23. PMID 30670156 DOI: 10.1016/j.freeradbiomed.2018.06.032  0.72
2018 Unnikrishnan A, Freeman WM, Jackson J, Wren JD, Porter H, Richardson A. The role of DNA methylation in epigenetics of aging. Pharmacology & Therapeutics. PMID 30419258 DOI: 10.1016/j.pharmthera.2018.11.001  0.6
2018 Qaisar R, Bhaskaran S, Premkumar P, Ranjit R, Natarajan KS, Ahn B, Riddle K, Claflin DR, Richardson A, Brooks SV, Van Remmen H. Oxidative stress-induced dysregulation of excitation-contraction coupling contributes to muscle weakness. Journal of Cachexia, Sarcopenia and Muscle. PMID 30073804 DOI: 10.1002/jcsm.12339  0.72
2018 Deepa SS, Pharaoh G, Kinter M, Diaz V, Fok WC, Riddle K, Pulliam D, Hill S, Fischer KE, Soto V, Georgescu C, Wren JD, Viscomi C, Richardson A, Van Remmen H. Lifelong reduction in complex IV induces tissue-specific metabolic effects but does not reduce lifespan or healthspan in mice. Aging Cell. e12769. PMID 29696791 DOI: 10.1111/acel.12769  0.72
2018 Deepa SS, Unnikrishnan A, Matyi S, Hadad N, Richardson A. Necroptosis increases with age and is reduced by dietary restriction. Aging Cell. e12770. PMID 29696779 DOI: 10.1111/acel.12770  0.6
2018 Hadad N, Unnikrishnan A, Jackson JA, Masser DR, Otalora L, Stanford DR, Richardson A, Freeman WM. Caloric restriction mitigates age-associated hippocampal differential CG and non-CG methylation. Neurobiology of Aging. 67: 53-66. PMID 29631215 DOI: 10.1016/j.neurobiolaging.2018.03.009  0.6
2018 Snider TA, Richardson A, Stoner JA, Deepa SS. The Geropathology Grading Platform demonstrates that mice null for Cu/Zn-superoxide dismutase show accelerated biological aging. Geroscience. PMID 29478190 DOI: 10.1007/s11357-018-0008-0  0.6
2018 Unnikrishnan A, Hadad N, Masser DR, Jackson J, Freeman WM, Richardson A. Revisiting the genomic hypomethylation hypothesis of aging. Annals of the New York Academy of Sciences. PMID 29363785 DOI: 10.1111/nyas.13533  0.6
2017 Sakellariou G, McDonagh B, Porter H, Giakoumaki I, Earl K, Nye G, Vasilaki A, Brooks S, Richardson A, Van Remmen H, McArdle A, Jackson MJ. Comparison of whole body SOD1 knockout with muscle specific SOD1 knockout mice reveals a role for nerve redox signaling in regulation of degenerative pathways in skeletal muscle. Antioxidants & Redox Signaling. PMID 29065712 DOI: 10.1089/ars.2017.7249  0.72
2017 Masser DR, Hadad N, Porter HL, Mangold CA, Unnikrishnan A, Ford MM, Giles CB, Georgescu C, Dozmorov MG, Wren JD, Richardson A, Stanford DR, Freeman WM. Sexually divergent DNA methylation patterns with hippocampal aging. Aging Cell. PMID 28948711 DOI: 10.1111/acel.12681  0.6
2017 Vasilaki A, Richardson A, Van Remmen H, Brooks SV, Larkin L, McArdle A, Jackson MJ. Role of nerve-muscle interactions and ROS in regulation of muscle proteostasis with aging. The Journal of Physiology. PMID 28792061 DOI: 10.1113/JP274336  0.72
2017 Unnikrishnan A, Jackson J, Matyi SA, Hadad N, Wronowski B, Georgescu C, Garrett KP, Wren JD, Freeman WM, Richardson A. Role of DNA methylation in the dietary restriction mediated cellular memory. Geroscience. PMID 28477138 DOI: 10.1007/s11357-017-9976-8  0.6
2017 Deepa SS, Bhaskaran S, Espinoza S, Brooks SV, McArdle A, Jackson MJ, Van Remmen H, Richardson A. A new mouse model of frailty: the Cu/Zn superoxide dismutase knockout mouse. Geroscience. PMID 28409332 DOI: 10.1007/s11357-017-9975-9  0.72
2016 Etzler JC, Bollo M, Holstein D, Deng JJ, Perez V, Lin DT, Richardson A, Bai Y, Lechleiter JD. Cyclophilin D over-expression increases mitochondrial complex III activity and accelerates supercomplex formation. Archives of Biochemistry and Biophysics. PMID 27916505 DOI: 10.1016/j.abb.2016.11.008  0.52
2016 Zhang Y, Unnikrishnan A, Deepa SS, Liu Y, Li Y, Ikeno Y, Sosnowska D, Van Remmen H, Richardson A. A new role for oxidative stress in aging: The accelerated aging phenotype in Sod1(-/)(-) mice is correlated to increased cellular senescence. Redox Biology. 11: 30-37. PMID 27846439 DOI: 10.1016/j.redox.2016.10.014  0.72
2016 Salmon AB, Kim G, Liu C, Wren JD, Georgescu C, Richardson A, Levine RL. Effects of transgenic methionine sulfoxide reductase A (MsrA) expression on lifespan and age-dependent changes in metabolic function in mice. Redox Biology. 10: 251-256. PMID 27821326 DOI: 10.1016/j.redox.2016.10.012  0.68
2016 Fischer KE, Hoffman JM, Sloane LB, Gelfond JA, Soto VY, Richardson AG, Austad SN. A cross-sectional study of male and female C57BL/6Nia mice suggests lifespan and healthspan are not necessarily correlated. Aging. PMID 27705904 DOI: 10.18632/aging.101059  0.48
2016 Hadad N, Masser DR, Logan S, Wronowski B, Mangold CA, Clark N, Otalora L, Unnikrishnan A, Ford MM, Giles CB, Wren JD, Richardson A, Sonntag WE, Stanford DR, Freeman W. Absence of genomic hypomethylation or regulation of cytosine-modifying enzymes with aging in male and female mice. Epigenetics & Chromatin. 9: 30. PMID 27413395 DOI: 10.1186/s13072-016-0080-6  0.68
2016 Strong R, Miller RA, Antebi A, Astle CM, Bogue M, Denzel MS, Fernandez E, Flurkey K, Hamilton KL, Lamming DW, Javors MA, de Magalhães JP, Marinez PA, McCord JM, Miller BF, ... ... Richardson A, et al. Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer. Aging Cell. PMID 27312235 DOI: 10.1111/acel.12496  0.68
2016 Richardson A, Pedley G, Pelone F, Akhtar F, Chang J, Muleya W, Greenwood N. Psychosocial interventions for people with young onset dementia and their carers: a systematic review. International Psychogeriatrics / Ipa. 1-14. PMID 27072752 DOI: 10.1017/S1041610216000132  0.4
2016 Zhang Y, Liu Y, Walsh M, Bokov A, Ikeno Y, Jang YC, Perez VI, Van Remmen H, Richardson A. Liver specific expression of Cu/ZnSOD extends the lifespan of Sod1 null mice. Mechanisms of Ageing and Development. PMID 26839948 DOI: 10.1016/j.mad.2016.01.005  0.72
2016 Richardson A, Austad SN, Ikeno Y, Unnikrishnan A, McCarter RJ. Significant life extension by ten percent dietary restriction. Annals of the New York Academy of Sciences. 1363: 11-7. PMID 26695614 DOI: 10.1111/nyas.12982  0.6
2015 Lin AL, Jahrling JB, Zhang W, DeRosa N, Bakshi V, Romero P, Galvan V, Richardson A. Rapamycin rescues vascular, metabolic and learning deficits in apolipoprotein E4 transgenic mice with pre-symptomatic Alzheimer's disease. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 26721390 DOI: 10.1177/0271678X15621575  0.36
2015 McAtee PA, Richardson AC, Nieuwenhuizen NJ, Gunaseelan K, Hoong L, Chen X, Atkinson RG, Burdon JN, David KM, Schaffer RJ. The hybrid non-ethylene and ethylene ripening response in kiwifruit (Actinidia chinensis) is associated with differential regulation of MADS-box transcription factors. Bmc Plant Biology. 15: 304. PMID 26714876 DOI: 10.1186/s12870-015-0697-9  0.72
2015 Ross C, Salmon A, Strong R, Fernandez E, Javors M, Richardson A, Tardif S. Metabolic consequences of long-term rapamycin exposure on common marmoset monkeys (Callithrix jacchus). Aging. PMID 26568298  0.32
2015 Hunnicut J, Liu Y, Richardson A, Salmon AB. MsrA Overexpression Targeted to the Mitochondria, but Not Cytosol, Preserves Insulin Sensitivity in Diet-Induced Obese Mice. Plos One. 10: e0139844. PMID 26448611 DOI: 10.1371/journal.pone.0139844  0.68
2015 Sataranatarajan K, Ikeno Y, Bokov A, Feliers D, Yalamanchili H, Lee HJ, Mariappan MM, Tabatabai-Mir H, Diaz V, Prasad S, Javors MA, Ghosh Choudhury G, Hubbard GB, Barnes JL, Richardson A, et al. Rapamycin Increases Mortality in db/db Mice, a Mouse Model of Type 2 Diabetes. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 26442901 DOI: 10.1093/gerona/glv170  0.6
2015 Nikolich-Žugich J, Goldman DP, Cohen PR, Cortese D, Fontana L, Kennedy BK, Mohler MJ, Olshansky SJ, Perls T, Perry D, Richardson A, Ritchie C, Wertheimer AM, Faragher RG, Fain MJ. Preparing for an Aging World: Engaging Biogerontologists, Geriatricians, and the Society. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 26419976 DOI: 10.1093/gerona/glv164  0.68
2015 Richardson A, Fischer KE, Speakman JR, de Cabo R, Mitchell SJ, Peterson CA, Rabinovitch P, Chiao YA, Taffet G, Miller RA, Rentería RC, Bower J, Ingram DK, Ladiges WC, Ikeno Y, et al. Measures of Healthspan as Indices of Aging in Mice-A Recommendation. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 26297941 DOI: 10.1093/gerona/glv080  0.68
2015 Fischer KE, Gelfond JA, Soto VY, Han C, Someya S, Richardson A, Austad SN. Health Effects of Long-Term Rapamycin Treatment: The Impact on Mouse Health of Enteric Rapamycin Treatment from Four Months of Age throughout Life. Plos One. 10: e0126644. PMID 25978367 DOI: 10.1371/journal.pone.0126644  0.68
2015 Sataranatarajan K, Qaisar R, Davis C, Sakellariou GK, Vasilaki A, Zhang Y, Liu Y, Bhaskaran S, McArdle A, Jackson M, Brooks SV, Richardson A, Van Remmen H. Neuron specific reduction in CuZnSOD is not sufficient to initiate a full sarcopenia phenotype. Redox Biology. 5: 140-148. PMID 25917273 DOI: 10.1016/j.redox.2015.04.005  0.72
2015 Zhang Y, Fischer KE, Soto V, Liu Y, Sosnowska D, Richardson A, Salmon AB. Obesity-induced oxidative stress, accelerated functional decline with age and increased mortality in mice. Archives of Biochemistry and Biophysics. 576: 39-48. PMID 25558793 DOI: 10.1016/j.abb.2014.12.018  0.68
2015 Richardson A, Galvan V, Lin AL, Oddo S. How longevity research can lead to therapies for Alzheimer's disease: The rapamycin story. Experimental Gerontology. 68: 51-8. PMID 25481271 DOI: 10.1016/j.exger.2014.12.002  0.36
2015 Tardif S, Ross C, Bergman P, Fernandez E, Javors M, Salmon A, Spross J, Strong R, Richardson A. Testing efficacy of administration of the antiaging drug rapamycin in a nonhuman primate, the common marmoset. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 70: 577-87. PMID 25038772 DOI: 10.1093/gerona/glu101  0.68
2015 Kwak HB, Lee Y, Kim JH, Van Remmen H, Richardson AG, Lawler JM. MnSOD overexpression reduces fibrosis and pro-apoptotic signaling in the aging mouse heart. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 70: 533-44. PMID 25016531 DOI: 10.1093/gerona/glu090  0.68
2014 Walsh ME, Sloane LB, Fischer KE, Austad SN, Richardson A, Van Remmen H. Use of Nerve Conduction Velocity to Assess Peripheral Nerve Health in Aging Mice. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 25477428 DOI: 10.1093/gerona/glu208  0.68
2014 Kennedy BK, Berger SL, Brunet A, Campisi J, Cuervo AM, Epel ES, Franceschi C, Lithgow GJ, Morimoto RI, Pessin JE, Rando TA, Richardson A, Schadt EE, Wyss-Coray T, Sierra F. Geroscience: linking aging to chronic disease. Cell. 159: 709-13. PMID 25417146 DOI: 10.1016/j.cell.2014.10.039  0.68
2014 Liu Y, Diaz V, Fernandez E, Strong R, Ye L, Baur JA, Lamming DW, Richardson A, Salmon AB. Rapamycin-induced metabolic defects are reversible in both lean and obese mice. Aging. 6: 742-54. PMID 25324470  0.68
2014 Fok WC, Livi C, Bokov A, Yu Z, Chen Y, Richardson A, Pérez VI. Short-term rapamycin treatment in mice has few effects on the transcriptome of white adipose tissue compared to dietary restriction. Mechanisms of Ageing and Development. 140: 23-9. PMID 25075714 DOI: 10.1016/j.mad.2014.07.004  0.6
2014 Richardson AG, Schadt EE. The role of macromolecular damage in aging and age-related disease. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 69: S28-32. PMID 24833583 DOI: 10.1093/gerona/glu056  0.68
2014 Fok WC, Chen Y, Bokov A, Zhang Y, Salmon AB, Diaz V, Javors M, Wood WH, Zhang Y, Becker KG, Pérez VI, Richardson A. Mice fed rapamycin have an increase in lifespan associated with major changes in the liver transcriptome. Plos One. 9: e83988. PMID 24409289 DOI: 10.1371/journal.pone.0083988  0.68
2014 Sakellariou GK, Davis CS, Shi Y, Ivannikov MV, Zhang Y, Vasilaki A, Macleod GT, Richardson A, Van Remmen H, Jackson MJ, McArdle A, Brooks SV. Neuron-specific expression of CuZnSOD prevents the loss of muscle mass and function that occurs in homozygous CuZnSOD-knockout mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 1666-81. PMID 24378874 DOI: 10.1096/fj.13-240390  0.68
2014 Fok WC, Bokov A, Gelfond J, Yu Z, Zhang Y, Doderer M, Chen Y, Javors M, Wood WH, Zhang Y, Becker KG, Richardson A, Pérez VI. Combined treatment of rapamycin and dietary restriction has a larger effect on the transcriptome and metabolome of liver. Aging Cell. 13: 311-9. PMID 24304444 DOI: 10.1111/acel.12175  0.68
2014 Darvin K, Randolph A, Ovalles S, Halade D, Breeding L, Richardson A, Espinoza SE. Plasma protein biomarkers of the geriatric syndrome of frailty. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 69: 182-6. PMID 24285743 DOI: 10.1093/gerona/glt183  0.68
2014 Zhang Y, Bokov A, Gelfond J, Soto V, Ikeno Y, Hubbard G, Diaz V, Sloane L, Maslin K, Treaster S, Réndon S, van Remmen H, Ward W, Javors M, Richardson A, et al. Rapamycin extends life and health in C57BL/6 mice. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 69: 119-30. PMID 23682161 DOI: 10.1093/gerona/glt056  0.68
2013 Liu Y, Qi W, Richardson A, Van Remmen H, Ikeno Y, Salmon AB. Oxidative damage associated with obesity is prevented by overexpression of CuZn- or Mn-superoxide dismutase. Biochemical and Biophysical Research Communications. 438: 78-83. PMID 23872067 DOI: 10.1016/j.bbrc.2013.07.029  0.72
2013 Lin AL, Pulliam DA, Deepa SS, Halloran JJ, Hussong SA, Burbank RR, Bresnen A, Liu Y, Podlutskaya N, Soundararajan A, Muir E, Duong TQ, Bokov AF, Viscomi C, Zeviani M, ... Richardson AG, et al. Decreased in vitro mitochondrial function is associated with enhanced brain metabolism, blood flow, and memory in Surf1-deficient mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 1605-11. PMID 23838831 DOI: 10.1038/jcbfm.2013.116  0.68
2013 Lin AL, Zheng W, Halloran JJ, Burbank RR, Hussong SA, Hart MJ, Javors M, Shih YY, Muir E, Solano Fonseca R, Strong R, Richardson AG, Lechleiter JD, Fox PT, Galvan V. Chronic rapamycin restores brain vascular integrity and function through NO synthase activation and improves memory in symptomatic mice modeling Alzheimer's disease. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 1412-21. PMID 23801246 DOI: 10.1038/jcbfm.2013.82  0.68
2013 Park JH, Glass Z, Sayed K, Michurina TV, Lazutkin A, Mineyeva O, Velmeshev D, Ward WF, Richardson A, Enikolopov G. Calorie restriction alleviates the age-related decrease in neural progenitor cell division in the aging brain. The European Journal of Neuroscience. 37: 1987-93. PMID 23773068 DOI: 10.1111/ejn.12249  0.68
2013 Zhang Y, Davis C, Sakellariou GK, Shi Y, Kayani AC, Pulliam D, Bhattacharya A, Richardson A, Jackson MJ, McArdle A, Brooks SV, Van Remmen H. CuZnSOD gene deletion targeted to skeletal muscle leads to loss of contractile force but does not cause muscle atrophy in adult mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 3536-48. PMID 23729587 DOI: 10.1096/fj.13-228130  0.72
2013 Zhang Y, Ikeno Y, Bokov A, Gelfond J, Jaramillo C, Zhang HM, Liu Y, Qi W, Hubbard G, Richardson A, Van Remmen H. Dietary restriction attenuates the accelerated aging phenotype of Sod1(-/-) mice. Free Radical Biology & Medicine. 60: 300-6. PMID 23459073 DOI: 10.1016/j.freeradbiomed.2013.02.026  0.72
2013 Styskal J, Nwagwu FA, Watkins YN, Liang H, Richardson A, Musi N, Salmon AB. Methionine sulfoxide reductase A affects insulin resistance by protecting insulin receptor function. Free Radical Biology & Medicine. 56: 123-32. PMID 23089224 DOI: 10.1016/j.freeradbiomed.2012.10.544  0.72
2013 Fok WC, Zhang Y, Salmon AB, Bhattacharya A, Gunda R, Jones D, Ward W, Fisher K, Richardson A, Pérez VI. Short-term treatment with rapamycin and dietary restriction have overlapping and distinctive effects in young mice. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 68: 108-16. PMID 22570137 DOI: 10.1093/gerona/gls127  0.68
2012 Sataranatarajan K, Feliers D, Mariappan MM, Lee HJ, Lee MJ, Day RT, Yalamanchili HB, Choudhury GG, Barnes JL, Van Remmen H, Richardson A, Kasinath BS. Molecular events in matrix protein metabolism in the aging kidney. Aging Cell. 11: 1065-73. PMID 23020145 DOI: 10.1111/acel.12008  0.68
2012 Salmon AB, Flores LC, Li Y, Van Remmen H, Richardson A, Ikeno Y. Reduction of glucose intolerance with high fat feeding is associated with anti-inflammatory effects of thioredoxin 1 overexpression in mice. Pathobiology of Aging & Age Related Diseases. 2. PMID 22953037 DOI: 10.3402/pba.v2i0.17101  0.72
2012 Tabatabai-Mir H, Sataranatarajan K, Lee HJ, Bokov AF, Fernandez E, Diaz V, Choudhury GG, Richardson A, Kasinath BS. Rapamycin selectively alters serum chemistry in diabetic mice. Pathobiology of Aging & Age Related Diseases. 2. PMID 22953036 DOI: 10.3402/pba.v2i0.15896  0.56
2012 Charchaflieh J, Labaze GI, Li P, Van Remmen H, Lee H, Stutz H, Richardson A, Emanuel A, Zhang M. Overexpression of human SOD1 improves survival of mice susceptible to endotoxic shock. Journal of Inflammation Research. 5: 51-8. PMID 22879777 DOI: 10.2147/JIR.S32073  0.72
2012 Jang YC, Liu Y, Hayworth CR, Bhattacharya A, Lustgarten MS, Muller FL, Chaudhuri A, Qi W, Li Y, Huang JY, Verdin E, Richardson A, Van Remmen H. Dietary restriction attenuates age-associated muscle atrophy by lowering oxidative stress in mice even in complete absence of CuZnSOD. Aging Cell. 11: 770-82. PMID 22672615 DOI: 10.1111/j.1474-9726.2012.00843.x  0.68
2012 Lustgarten MS, Bhattacharya A, Muller FL, Jang YC, Shimizu T, Shirasawa T, Richardson A, Van Remmen H. Complex I generated, mitochondrial matrix-directed superoxide is released from the mitochondria through voltage dependent anion channels. Biochemical and Biophysical Research Communications. 422: 515-21. PMID 22613204 DOI: 10.1016/j.bbrc.2012.05.055  0.68
2012 Robbins D, Wittwer JA, Codarin S, Circu ML, Aw TY, Huang TT, Van Remmen H, Richardson A, Wang DB, Witt SN, Klein RL, Zhao Y. Isocitrate dehydrogenase 1 is downregulated during early skin tumorigenesis which can be inhibited by overexpression of manganese superoxide dismutase. Cancer Science. 103: 1429-33. PMID 22533343 DOI: 10.1111/j.1349-7006.2012.02317.x  0.68
2012 Lamming DW, Ye L, Katajisto P, Goncalves MD, Saitoh M, Stevens DM, Davis JG, Salmon AB, Richardson A, Ahima RS, Guertin DA, Sabatini DM, Baur JA. Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity. Science (New York, N.Y.). 335: 1638-43. PMID 22461615 DOI: 10.1126/science.1215135  0.68
2012 Yoo SE, Chen L, Na R, Liu Y, Rios C, Van Remmen H, Richardson A, Ran Q. Gpx4 ablation in adult mice results in a lethal phenotype accompanied by neuronal loss in brain. Free Radical Biology & Medicine. 52: 1820-7. PMID 22401858 DOI: 10.1016/j.freeradbiomed.2012.02.043  0.72
2012 Shamsi KS, Pierce A, Ashton AS, Halade DG, Richardson A, Espinoza SE. Proteomic screening of glycoproteins in human plasma for frailty biomarkers. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 67: 853-64. PMID 22219522 DOI: 10.1093/gerona/glr224  0.36
2012 Majumder S, Caccamo A, Medina DX, Benavides AD, Javors MA, Kraig E, Strong R, Richardson A, Oddo S. Lifelong rapamycin administration ameliorates age-dependent cognitive deficits by reducing IL-1β and enhancing NMDA signaling. Aging Cell. 11: 326-35. PMID 22212527 DOI: 10.1111/j.1474-9726.2011.00791.x  0.68
2012 Styskal J, Van Remmen H, Richardson A, Salmon AB. Oxidative stress and diabetes: what can we learn about insulin resistance from antioxidant mutant mouse models? Free Radical Biology & Medicine. 52: 46-58. PMID 22056908 DOI: 10.1016/j.freeradbiomed.2011.10.441  0.72
2012 Bhattacharya A, Bokov A, Muller FL, Jernigan AL, Maslin K, Diaz V, Richardson A, Van Remmen H. Dietary restriction but not rapamycin extends disease onset and survival of the H46R/H48Q mouse model of ALS. Neurobiology of Aging. 33: 1829-32. PMID 21763036 DOI: 10.1016/j.neurobiolaging.2011.06.002  0.68
2011 Bokov AF, Garg N, Ikeno Y, Thakur S, Musi N, DeFronzo RA, Zhang N, Erickson RC, Gelfond J, Hubbard GB, Adamo ML, Richardson A. Does reduced IGF-1R signaling in Igf1r+/- mice alter aging? Plos One. 6: e26891. PMID 22132081 DOI: 10.1371/journal.pone.0026891  0.6
2011 Liang H, Ward WF, Jang YC, Bhattacharya A, Bokov AF, Li Y, Jernigan A, Richardson A, Van Remmen H. PGC-1α protects neurons and alters disease progression in an amyotrophic lateral sclerosis mouse model. Muscle & Nerve. 44: 947-56. PMID 22102466 DOI: 10.1002/mus.22217  0.68
2011 Majumder S, Richardson A, Strong R, Oddo S. Inducing autophagy by rapamycin before, but not after, the formation of plaques and tangles ameliorates cognitive deficits. Plos One. 6: e25416. PMID 21980451 DOI: 10.1371/journal.pone.0025416  0.68
2011 Larkin LM, Davis CS, Sims-Robinson C, Kostrominova TY, Van Remmen H, Richardson A, Feldman EL, Brooks SV. Skeletal muscle weakness due to deficiency of CuZn-superoxide dismutase is associated with loss of functional innervation. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 301: R1400-7. PMID 21900648 DOI: 10.1152/ajpregu.00093.2011  0.72
2011 Pérez VI, Cortez LA, Lew CM, Rodriguez M, Webb CR, Van Remmen H, Chaudhuri A, Qi W, Lee S, Bokov A, Fok W, Jones D, Richardson A, Yodoi J, Zhang Y, et al. Thioredoxin 1 overexpression extends mainly the earlier part of life span in mice. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 66: 1286-99. PMID 21873593 DOI: 10.1093/gerona/glr125  0.68
2011 Ghosh S, Lertwattanarak R, Lefort N, Molina-Carrion M, Joya-Galeana J, Bowen BP, Garduno-Garcia Jde J, Abdul-Ghani M, Richardson A, DeFronzo RA, Mandarino L, Van Remmen H, Musi N. Reduction in reactive oxygen species production by mitochondria from elderly subjects with normal and impaired glucose tolerance. Diabetes. 60: 2051-60. PMID 21677280 DOI: 10.2337/db11-0121  0.68
2011 Wittwer JA, Robbins D, Wang F, Codarin S, Shen X, Kevil CG, Huang TT, Van Remmen H, Richardson A, Zhao Y. Enhancing mitochondrial respiration suppresses tumor promoter TPA-induced PKM2 expression and cell transformation in skin epidermal JB6 cells. Cancer Prevention Research (Philadelphia, Pa.). 4: 1476-84. PMID 21673231 DOI: 10.1158/1940-6207.CAPR-11-0028  0.72
2011 Bhattacharya A, Leonard S, Tardif S, Buffenstein R, Fischer KE, Richardson A, Austad SN, Chaudhuri AR. Attenuation of liver insoluble protein carbonyls: indicator of a longevity determinant? Aging Cell. 10: 720-3. PMID 21463461 DOI: 10.1111/j.1474-9726.2011.00712.x  0.68
2011 Sakellariou GK, Pye D, Vasilaki A, Zibrik L, Palomero J, Kabayo T, McArdle F, Van Remmen H, Richardson A, Tidball JG, McArdle A, Jackson MJ. Role of superoxide-nitric oxide interactions in the accelerated age-related loss of muscle mass in mice lacking Cu,Zn superoxide dismutase. Aging Cell. 10: 749-60. PMID 21443684 DOI: 10.1111/j.1474-9726.2011.00709.x  0.72
2011 Sharp ZD, Richardson A. Aging and cancer: can mTOR inhibitors kill two birds with one drug? Targeted Oncology. 6: 41-51. PMID 21394528 DOI: 10.1007/s11523-011-0168-7  0.68
2011 Lustgarten MS, Jang YC, Liu Y, Qi W, Qin Y, Dahia PL, Shi Y, Bhattacharya A, Muller FL, Shimizu T, Shirasawa T, Richardson A, Van Remmen H. MnSOD deficiency results in elevated oxidative stress and decreased mitochondrial function but does not lead to muscle atrophy during aging. Aging Cell. 10: 493-505. PMID 21385310 DOI: 10.1111/j.1474-9726.2011.00695.x  0.68
2011 Sun LY, Bokov AF, Richardson A, Miller RA. Hepatic response to oxidative injury in long-lived Ames dwarf mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 398-408. PMID 20826540 DOI: 10.1096/fj.10-164376  0.68
2010 Pierce A, Wei R, Halade D, Yoo SE, Ran Q, Richardson A. A Novel mouse model of enhanced proteostasis: Full-length human heat shock factor 1 transgenic mice. Biochemical and Biophysical Research Communications. 402: 59-65. PMID 20920476 DOI: 10.1016/j.bbrc.2010.09.111  0.6
2010 Vasilaki A, van der Meulen JH, Larkin L, Harrison DC, Pearson T, Van Remmen H, Richardson A, Brooks SV, Jackson MJ, McArdle A. The age-related failure of adaptive responses to contractile activity in skeletal muscle is mimicked in young mice by deletion of Cu,Zn superoxide dismutase. Aging Cell. 9: 979-90. PMID 20883524 DOI: 10.1111/j.1474-9726.2010.00635.x  0.68
2010 Pérez VI, Pierce A, de Waal EM, Ward WF, Bokov A, Chaudhuri A, Richardson A. Detection and quantification of protein disulfides in biological tissues a fluorescence-based proteomic approach. Methods in Enzymology. 473: 161-77. PMID 20513477 DOI: 10.1016/S0076-6879(10)73008-1  0.68
2010 Khodr CE, Clark S, Bokov AF, Richardson A, Strong R, Hurley DL, Phelps CJ. Early postnatal administration of growth hormone increases tuberoinfundibular dopaminergic neuron numbers in Ames dwarf mice. Endocrinology. 151: 3277-85. PMID 20463054 DOI: 10.1210/en.2009-1482  0.68
2010 Spilman P, Podlutskaya N, Hart MJ, Debnath J, Gorostiza O, Bredesen D, Richardson A, Strong R, Galvan V. Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-β levels in a mouse model of alzheimer's disease Plos One. 5. PMID 20376313 DOI: 10.1371/journal.pone.0009979  0.68
2010 Caccamo A, Majumder S, Richardson A, Strong R, Oddo S. Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments. The Journal of Biological Chemistry. 285: 13107-20. PMID 20178983 DOI: 10.1074/jbc.M110.100420  0.68
2010 Jang YC, Lustgarten MS, Liu Y, Muller FL, Bhattacharya A, Liang H, Salmon AB, Brooks SV, Larkin L, Hayworth CR, Richardson A, Van Remmen H. Increased superoxide in vivo accelerates age-associated muscle atrophy through mitochondrial dysfunction and neuromuscular junction degeneration. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 1376-90. PMID 20040516 DOI: 10.1096/fj.09-146308  0.68
2010 Salmon AB, Richardson A, Pérez VI. Update on the oxidative stress theory of aging: does oxidative stress play a role in aging or healthy aging? Free Radical Biology & Medicine. 48: 642-55. PMID 20036736 DOI: 10.1016/j.freeradbiomed.2009.12.015  0.68
2010 McClung JM, Deruisseau KC, Whidden MA, Van Remmen H, Richardson A, Song W, Vrabas IS, Powers SK. Overexpression of antioxidant enzymes in diaphragm muscle does not alter contraction-induced fatigue or recovery. Experimental Physiology. 95: 222-31. PMID 19783618 DOI: 10.1113/expphysiol.2009.049650  0.68
2009 Hoehn KL, Salmon AB, Hohnen-Behrens C, Turner N, Hoy AJ, Maghzal GJ, Stocker R, Van Remmen H, Kraegen EW, Cooney GJ, Richardson AR, James DE. Insulin resistance is a cellular antioxidant defense mechanism. Proceedings of the National Academy of Sciences of the United States of America. 106: 17787-92. PMID 19805130 DOI: 10.1073/pnas.0902380106  0.68
2009 Lustgarten MS, Jang YC, Liu Y, Muller FL, Qi W, Steinhelper M, Brooks SV, Larkin L, Shimizu T, Shirasawa T, McManus LM, Bhattacharya A, Richardson A, Van Remmen H. Conditional knockout of Mn-SOD targeted to type IIB skeletal muscle fibers increases oxidative stress and is sufficient to alter aerobic exercise capacity. American Journal of Physiology. Cell Physiology. 297: C1520-32. PMID 19776389 DOI: 10.1152/ajpcell.00372.2009  0.68
2009 Zhang Y, Ikeno Y, Qi W, Chaudhuri A, Li Y, Bokov A, Thorpe SR, Baynes JW, Epstein C, Richardson A, Van Remmen H. Mice deficient in both Mn superoxide dismutase and glutathione peroxidase-1 have increased oxidative damage and a greater incidence of pathology but no reduction in longevity. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 64: 1212-20. PMID 19776219 DOI: 10.1093/gerona/glp132  0.68
2009 Liang H, Yoo SE, Na R, Walter CA, Richardson A, Ran Q. Short form glutathione peroxidase 4 is the essential isoform required for survival and somatic mitochondrial functions. The Journal of Biological Chemistry. 284: 30836-44. PMID 19744930 DOI: 10.1074/jbc.M109.032839  0.72
2009 Jang YC, Pérez VI, Song W, Lustgarten MS, Salmon AB, Mele J, Qi W, Liu Y, Liang H, Chaudhuri A, Ikeno Y, Epstein CJ, Van Remmen H, Richardson A. Overexpression of Mn superoxide dismutase does not increase life span in mice. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 64: 1114-25. PMID 19633237 DOI: 10.1093/gerona/glp100  0.68
2009 Bokov AF, Ko D, Richardson A. The effect of gonadectomy and estradiol on sensitivity to oxidative stress. Endocrine Research. 34: 43-58. PMID 19557590 DOI: 10.1080/07435800902913600  0.68
2009 Pérez VI, Bokov A, Van Remmen H, Mele J, Ran Q, Ikeno Y, Richardson A. Is the oxidative stress theory of aging dead? Biochimica Et Biophysica Acta. 1790: 1005-14. PMID 19524016 DOI: 10.1016/j.bbagen.2009.06.003  0.72
2009 Salmon AB, Pérez VI, Bokov A, Jernigan A, Kim G, Zhao H, Levine RL, Richardson A. Lack of methionine sulfoxide reductase A in mice increases sensitivity to oxidative stress but does not diminish life span. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 3601-8. PMID 19487311 DOI: 10.1096/fj.08-127415  0.68
2009 Ladiges W, Van Remmen H, Strong R, Ikeno Y, Treuting P, Rabinovitch P, Richardson A. Lifespan extension in genetically modified mice. Aging Cell. 8: 346-52. PMID 19485964 DOI: 10.1111/j.1474-9726.2009.00491.x  0.72
2009 Liang H, Ran Q, Jang YC, Holstein D, Lechleiter J, McDonald-Marsh T, Musatov A, Song W, Van Remmen H, Richardson A. Glutathione peroxidase 4 differentially regulates the release of apoptogenic proteins from mitochondria. Free Radical Biology & Medicine. 47: 312-20. PMID 19447173 DOI: 10.1016/j.freeradbiomed.2009.05.012  0.72
2009 Bokov AF, Lindsey ML, Khodr C, Sabia MR, Richardson A. Long-lived ames dwarf mice are resistant to chemical stressors. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 64: 819-27. PMID 19414510 DOI: 10.1093/gerona/glp052  0.68
2009 Salmon AB, Leonard S, Masamsetti V, Pierce A, Podlutsky AJ, Podlutskaya N, Richardson A, Austad SN, Chaudhuri AR. The long lifespan of two bat species is correlated with resistance to protein oxidation and enhanced protein homeostasis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 2317-26. PMID 19244163 DOI: 10.1096/fj.08-122523  0.68
2009 Liu X, Liu M, Zhang J, Bai X, Ramos F, Van Remmen H, Richardson A, Liu FY, Dong LQ, Liu F. Downregulation of Grb2 contributes to the insulin-sensitizing effect of calorie restriction. American Journal of Physiology. Endocrinology and Metabolism. 296: E1067-75. PMID 19240254 DOI: 10.1152/ajpendo.90714.2008  0.72
2009 Pérez VI, Buffenstein R, Masamsetti V, Leonard S, Salmon AB, Mele J, Andziak B, Yang T, Edrey Y, Friguet B, Ward W, Richardson A, Chaudhuri A. Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat. Proceedings of the National Academy of Sciences of the United States of America. 106: 3059-64. PMID 19223593 DOI: 10.1073/pnas.0809620106  0.68
2009 Liang H, Balas B, Tantiwong P, Dube J, Goodpaster BH, O'Doherty RM, DeFronzo RA, Richardson A, Musi N, Ward WF. Whole body overexpression of PGC-1alpha has opposite effects on hepatic and muscle insulin sensitivity. American Journal of Physiology. Endocrinology and Metabolism. 296: E945-54. PMID 19208857 DOI: 10.1152/ajpendo.90292.2008  0.68
2009 Pérez VI, Van Remmen H, Bokov A, Epstein CJ, Vijg J, Richardson A. The overexpression of major antioxidant enzymes does not extend the lifespan of mice. Aging Cell. 8: 73-5. PMID 19077044 DOI: 10.1111/j.1474-9726.2008.00449.x  0.68
2009 Larosche I, Choumar A, Fromenty B, Lettéron P, Abbey-Toby A, Van Remmen H, Epstein CJ, Richardson A, Feldmann G, Pessayre D, Mansouri A. Prolonged ethanol administration depletes mitochondrial DNA in MnSOD-overexpressing transgenic mice, but not in their wild type littermates. Toxicology and Applied Pharmacology. 234: 326-38. PMID 19063909 DOI: 10.1016/j.taap.2008.11.004  0.68
2009 Aliev G, Liu J, Shenk JC, Fischbach K, Pacheco GJ, Chen SG, Obrenovich ME, Ward WF, Richardson AG, Smith MA, Gasimov E, Perry G, Ames BN. Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats. Journal of Cellular and Molecular Medicine. 13: 320-33. PMID 18373733 DOI: 10.1111/j.1582-4934.2008.00324.x  0.68
2008 Chen L, Na R, Gu M, Salmon AB, Liu Y, Liang H, Qi W, Van Remmen H, Richardson A, Ran Q. Reduction of mitochondrial H2O2 by overexpressing peroxiredoxin 3 improves glucose tolerance in mice. Aging Cell. 7: 866-78. PMID 18778410 DOI: 10.1111/j.1474-9726.2008.00432.x  0.72
2008 Muller FL, Liu Y, Jernigan A, Borchelt D, Richardson A, Van Remmen H. MnSOD deficiency has a differential effect on disease progression in two different ALS mutant mouse models Muscle and Nerve. 38: 1173-1183. PMID 18720509 DOI: 10.1002/mus.21049  0.68
2008 Pierce A, Mirzaei H, Muller F, De Waal E, Taylor AB, Leonard S, Van Remmen H, Regnier F, Richardson A, Chaudhuri A. GAPDH is conformationally and functionally altered in association with oxidative stress in mouse models of amyotrophic lateral sclerosis. Journal of Molecular Biology. 382: 1195-210. PMID 18706911 DOI: 10.1016/j.jmb.2008.07.088  0.68
2008 Chen L, Na R, Gu M, Richardson A, Ran Q. Lipid peroxidation up-regulates BACE1 expression in vivo: a possible early event of amyloidogenesis in Alzheimer's disease. Journal of Neurochemistry. 107: 197-207. PMID 18680556 DOI: 10.1111/j.1471-4159.2008.05603.x  0.6
2008 Han ES, Muller FL, Pérez VI, Qi W, Liang H, Xi L, Fu C, Doyle E, Hickey M, Cornell J, Epstein CJ, Roberts LJ, Van Remmen H, Richardson A. The in vivo gene expression signature of oxidative stress. Physiological Genomics. 34: 112-26. PMID 18445702 DOI: 10.1152/physiolgenomics.00239.2007  0.68
2008 Guo Z, Ran Q, Roberts LJ, Zhou L, Richardson A, Sharan C, Wu D, Yang H. Suppression of atherogenesis by overexpression of glutathione peroxidase-4 in apolipoprotein E-deficient mice. Free Radical Biology & Medicine. 44: 343-52. PMID 18215741 DOI: 10.1016/j.freeradbiomed.2007.09.009  0.6
2008 Pérez VI, Lew CM, Cortez LA, Webb CR, Rodriguez M, Liu Y, Qi W, Li Y, Chaudhuri A, Van Remmen H, Richardson A, Ikeno Y. Thioredoxin 2 haploinsufficiency in mice results in impaired mitochondrial function and increased oxidative stress. Free Radical Biology & Medicine. 44: 882-92. PMID 18164269 DOI: 10.1016/j.freeradbiomed.2007.11.018  0.68
2007 Vasilaki A, Simpson D, McArdle F, McLean L, Beynon RJ, Van Remmen H, Richardson AG, McArdle A, Faulkner JA, Jackson MJ. Formation of 3-nitrotyrosines in carbonic anhydrase III is a sensitive marker of oxidative stress in skeletal muscle. Proteomics. Clinical Applications. 1: 362-72. PMID 21136689 DOI: 10.1002/prca.200600702  0.68
2007 Heydari AR, Unnikrishnan A, Lucente LV, Richardson A. Caloric restriction and genomic stability. Nucleic Acids Research. 35: 7485-96. PMID 17942423 DOI: 10.1093/nar/gkm860  0.68
2007 Ran Q, Liang H, Ikeno Y, Qi W, Prolla TA, Roberts LJ, Wolf N, Van Remmen H, VanRemmen H, Richardson A. Reduction in glutathione peroxidase 4 increases life span through increased sensitivity to apoptosis. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 62: 932-42. PMID 17895430  0.72
2007 Muller FL, Lustgarten MS, Jang Y, Richardson A, Van Remmen H. Trends in oxidative aging theories. Free Radical Biology & Medicine. 43: 477-503. PMID 17640558 DOI: 10.1016/j.freeradbiomed.2007.03.034  0.68
2007 Muller FL, Song W, Jang YC, Liu Y, Sabia M, Richardson A, Van Remmen H. Denervation-induced skeletal muscle atrophy is associated with increased mitochondrial ROS production. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 293: R1159-68. PMID 17584954 DOI: 10.1152/ajpregu.00767.2006  0.68
2007 Liang H, Bai Y, Li Y, Richardson A, Ward WF. PGC-1alpha-induced mitochondrial alterations in 3T3 fibroblast cells. Annals of the New York Academy of Sciences. 1100: 264-79. PMID 17460188 DOI: 10.1196/annals.1395.028  0.72
2007 Liang H, Van Remmen H, Frohlich V, Lechleiter J, Richardson A, Ran Q. Gpx4 protects mitochondrial ATP generation against oxidative damage. Biochemical and Biophysical Research Communications. 356: 893-8. PMID 17395155 DOI: 10.1016/j.bbrc.2007.03.045  0.72
2007 Chang J, Cornell JE, Van Remmen H, Hakala K, Ward WF, Richardson A. Effect of aging and caloric restriction on the mitochondrial proteome. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 62: 223-34. PMID 17389719  0.72
2007 Zhang Y, Padalecki SS, Chaudhuri AR, De Waal E, Goins BA, Grubbs B, Ikeno Y, Richardson A, Mundy GR, Herman B. Caspase-2 deficiency enhances aging-related traits in mice. Mechanisms of Ageing and Development. 128: 213-21. PMID 17188333 DOI: 10.1016/j.mad.2006.11.030  0.68
2007 Kostrominova TY, Pasyk KA, Van Remmen H, Richardson AG, Faulkner JA. Adaptive changes in structure of skeletal muscles from adult Sod1 homozygous knockout mice. Cell and Tissue Research. 327: 595-605. PMID 17109119 DOI: 10.1007/s00441-006-0297-y  0.68
2006 Chaudhuri AR, de Waal EM, Pierce A, Van Remmen H, Ward WF, Richardson A. Detection of protein carbonyls in aging liver tissue: A fluorescence-based proteomic approach. Mechanisms of Ageing and Development. 127: 849-61. PMID 17002888 DOI: 10.1016/j.mad.2006.08.006  0.68
2006 Cabelof DC, Ikeno Y, Nyska A, Busuttil RA, Anyangwe N, Vijg J, Matherly LH, Tucker JD, Wilson SH, Richardson A, Heydari AR. Haploinsufficiency in DNA polymerase beta increases cancer risk with age and alters mortality rate. Cancer Research. 66: 7460-5. PMID 16885342 DOI: 10.1158/0008-5472.CAN-06-1177  0.68
2006 Mele J, Van Remmen H, Vijg J, Richardson A. Characterization of transgenic mice that overexpress both copper zinc superoxide dismutase and catalase. Antioxidants & Redox Signaling. 8: 628-38. PMID 16677106 DOI: 10.1089/ars.2006.8.628  0.68
2006 Rader EP, Song W, Van Remmen H, Richardson A, Faulkner JA. Raising the antioxidant levels within mouse muscle fibres does not affect contraction-induced injury. Experimental Physiology. 91: 781-9. PMID 16675501 DOI: 10.1113/expphysiol.2005.033043  0.68
2006 Ran Q, Gu M, Van Remmen H, Strong R, Roberts JL, Richardson A. Glutathione peroxidase 4 protects cortical neurons from oxidative injury and amyloid toxicity. Journal of Neuroscience Research. 84: 202-8. PMID 16673405 DOI: 10.1002/jnr.20868  0.68
2006 Pierce A, deWaal E, Van Remmen H, VanRemmen H, Richardson A, Chaudhuri A. A novel approach for screening the proteome for changes in protein conformation. Biochemistry. 45: 3077-85. PMID 16503663 DOI: 10.1021/bi052031i  0.72
2006 Mansouri A, Muller FL, Liu Y, Ng R, Faulkner J, Hamilton M, Richardson A, Huang TT, Epstein CJ, Van Remmen H. Alterations in mitochondrial function, hydrogen peroxide release and oxidative damage in mouse hind-limb skeletal muscle during aging. Mechanisms of Ageing and Development. 127: 298-306. PMID 16405961 DOI: 10.1016/j.mad.2005.11.004  0.68
2005 Ikeno Y, Hubbard GB, Lee S, Richardson A, Strong R, Diaz V, Nelson JF. Housing density does not influence the longevity effect of calorie restriction. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 60: 1510-7. PMID 16424282  0.6
2005 Warner H, Anderson J, Austad S, Bergamini E, Bredesen D, Butler R, Carnes BA, Clark BF, Cristofalo V, Faulkner J, Guarente L, Harrison DE, Kirkwood T, Lithgow G, Martin G, ... ... Richardson A, et al. Science fact and the SENS agenda. What can we reasonably expect from ageing research? Embo Reports. 6: 1006-8. PMID 16264422 DOI: 10.1038/sj.embor.7400555  0.68
2005 Ward WF, Qi W, Van Remmen H, Zackert WE, Roberts LJ, Richardson A. Effects of age and caloric restriction on lipid peroxidation: measurement of oxidative stress by F2-isoprostane levels. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 60: 847-51. PMID 16079206  0.72
2005 Stadtman ER, Van Remmen H, Richardson A, Wehr NB, Levine RL. Methionine oxidation and aging. Biochimica Et Biophysica Acta. 1703: 135-40. PMID 15680221 DOI: 10.1016/j.bbapap.2004.08.010  0.68
2004 Chang J, Van Remmen H, Ward WF, Regnier FE, Richardson A, Cornell J. Processing of data generated by 2-dimensional gel electrophoresis for statistical analysis: missing data, normalization, and statistics. Journal of Proteome Research. 3: 1210-8. PMID 15595730 DOI: 10.1021/pr049886m  0.68
2004 Bokov A, Chaudhuri A, Richardson A. The role of oxidative damage and stress in aging. Mechanisms of Ageing and Development. 125: 811-26. PMID 15541775 DOI: 10.1016/j.mad.2004.07.009  0.6
2004 Yang H, Roberts LJ, Shi MJ, Zhou LC, Ballard BR, Richardson A, Guo ZM. Retardation of atherosclerosis by overexpression of catalase or both Cu/Zn-superoxide dismutase and catalase in mice lacking apolipoprotein E. Circulation Research. 95: 1075-81. PMID 15528470 DOI: 10.1161/01.RES.0000149564.49410.0d  0.56
2004 Fu C, Xi L, Wu Y, McCarter R, Richardson A, Hickey M, Han ES. Hepatic genes altered in expression by food restriction are not influenced by the low plasma glucose level in young male GLUT4 transgenic mice. The Journal of Nutrition. 134: 2965-74. PMID 15514260  0.44
2004 Ran Q, Liang H, Gu M, Qi W, Walter CA, Roberts LJ, Herman B, Richardson A, Van Remmen H. Transgenic mice overexpressing glutathione peroxidase 4 are protected against oxidative stress-induced apoptosis. The Journal of Biological Chemistry. 279: 55137-46. PMID 15496407 DOI: 10.1074/jbc.M410387200  0.72
2004 Richardson A, Liu F, Adamo ML, Van Remmen H, Nelson JF. The role of insulin and insulin-like growth factor-I in mammalian ageing. Best Practice & Research. Clinical Endocrinology & Metabolism. 18: 393-406. PMID 15261845 DOI: 10.1016/j.beem.2004.02.002  0.72
2004 Butler RN, Sprott R, Warner H, Bland J, Feuers R, Forster M, Fillit H, Harman SM, Hewitt M, Hyman M, Johnson K, Kligman E, McClearn G, Nelson J, Richardson A, et al. Biomarkers of aging: from primitive organisms to humans. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 59: B560-7. PMID 15215265  0.68
2004 Van Remmen H, Qi W, Sabia M, Freeman G, Estlack L, Yang H, Mao Guo Z, Huang TT, Strong R, Lee S, Epstein CJ, Richardson A. Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress. Free Radical Biology & Medicine. 36: 1625-34. PMID 15182862 DOI: 10.1016/j.freeradbiomed.2004.03.016  0.68
2004 Yang H, Shi M, Story J, Richardson A, Guo Z. Food restriction attenuates age-related increase in the sensitivity of endothelial cells to oxidized lipids. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 59: 316-23. PMID 15071074  0.56
2004 Han ES, Wu Y, McCarter R, Nelson JF, Richardson A, Hilsenbeck SG. Reproducibility, sources of variability, pooling, and sample size: important considerations for the design of high-density oligonucleotide array experiments. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 59: 306-15. PMID 15071073  0.44
2004 Chen X, Liang H, Van Remmen H, Vijg J, Richardson A. Catalase transgenic mice: characterization and sensitivity to oxidative stress. Archives of Biochemistry and Biophysics. 422: 197-210. PMID 14759608 DOI: 10.1016/j.abb.2003.12.023  0.72
2003 Liang H, Masoro EJ, Nelson JF, Strong R, McMahan CA, Richardson A. Genetic mouse models of extended lifespan. Experimental Gerontology. 38: 1353-64. PMID 14698816  0.72
2003 Van Remmen H, Ikeno Y, Hamilton M, Pahlavani M, Wolf N, Thorpe SR, Alderson NL, Baynes JW, Epstein CJ, Huang TT, Nelson J, Strong R, Richardson A. Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging. Physiological Genomics. 16: 29-37. PMID 14679299 DOI: 10.1152/physiolgenomics.00122.2003  0.68
2003 Richardson A. The Sam and Ann Barshop Center for Longevity and Aging Studies. Interview by Vicki Glaser. Journal of Anti-Aging Medicine. 6: 73-6. PMID 14614796 DOI: 10.1089/109454503769684748  0.68
2003 Ran Q, Van Remmen H, Gu M, Qi W, Roberts LJ, Prolla T, Richardson A. Embryonic fibroblasts from Gpx4+/- mice: a novel model for studying the role of membrane peroxidation in biological processes. Free Radical Biology & Medicine. 35: 1101-9. PMID 14572612  0.72
2003 Cabelof DC, Guo Z, Raffoul JJ, Sobol RW, Wilson SH, Richardson A, Heydari AR. Base excision repair deficiency caused by polymerase beta haploinsufficiency: accelerated DNA damage and increased mutational response to carcinogens. Cancer Research. 63: 5799-807. PMID 14522902  0.68
2003 Yang H, Shi M, Richardson A, Vijg J, Guo Z. Attenuation of leukocyte-endothelium interaction by antioxidant enzymes. Free Radical Biology & Medicine. 35: 266-76. PMID 12885588  0.72
2003 Morgan WW, Richardson AG, Nelson JF. Dietary restriction does not protect the nigrostriatal dopaminergic pathway of older animals from low-dose MPTP-induced neurotoxicity. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 58: B394-9. PMID 12730246  0.68
2003 Chen X, Mele J, Giese H, Van Remmen H, Dollé ME, Steinhelper M, Richardson A, Vijg J. A strategy for the ubiquitous overexpression of human catalase and CuZn superoxide dismutase genes in transgenic mice. Mechanisms of Ageing and Development. 124: 219-27. PMID 12633942  0.72
2003 Chang J, Van Remmen H, Cornell J, Richardson A, Ward WF. Comparative proteomics: characterization of a two-dimensional gel electrophoresis system to study the effect of aging on mitochondrial proteins. Mechanisms of Ageing and Development. 124: 33-41. PMID 12618004  0.72
2003 Sharp ZD, Lee WH, Nikitin AY, Flesken-Nikitin A, Ikeno Y, Reddick R, Richardson AG, Nelson JF. Minimal effects of dietary restriction on neuroendocrine carcinogenesis in Rb+/- mice. Carcinogenesis. 24: 179-83. PMID 12584165 DOI: 10.1093/carcin/24.2.179  0.68
2003 Yant LJ, Ran Q, Rao L, Van Remmen H, Shibatani T, Belter JG, Motta L, Richardson A, Prolla TA. The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults. Free Radical Biology & Medicine. 34: 496-502. PMID 12566075  0.72
2003 Yang H, Shi M, VanRemmen H, Chen X, Vijg J, Richardson A, Guo Z. Reduction of pressor response to vasoconstrictor agents by overexpression of catalase in mice. American Journal of Hypertension. 16: 1-5. PMID 12517675  0.72
2002 Dong LQ, Ramos FJ, Wick MJ, Lim MA, Guo Z, Strong R, Richardson A, Liu F. Cloning and characterization of a testis and brain-specific isoform of mouse 3'-phosphoinositide-dependent protein kinase-1, mPDK-1 beta. Biochemical and Biophysical Research Communications. 294: 136-44. PMID 12054753 DOI: 10.1016/S0006-291X(02)00449-7  0.68
2001 Guo Z, Van Remmen H, Yang H, Chen X, Mele J, Vijg J, Epstein CJ, Ho YS, Richardson A. Changes in expression of antioxidant enzymes affect cell-mediated LDL oxidation and oxidized LDL-induced apoptosis in mouse aortic cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 21: 1131-8. PMID 11451741  0.68
2001 Pahlavani MA, Mele JF, Richardson A. Effect of overexpression of human Cu/Zn-SOD on activation-induced lymphocyte proliferation and apoptosis. Free Radical Biology & Medicine. 30: 1319-27. PMID 11368930 DOI: 10.1016/S0891-5849(01)00529-9  0.68
1997 Richardson A. Animal models of aging Aging Clinical and Experimental Research. 9: 439-440. PMID 9553631  0.68
1991 Richardson A. Changes in the expression of genes involved in protecting cells against stress and free radicals Aging Clinical and Experimental Research. 3: 403-405. PMID 1841618 DOI: 10.1007/BF03324050  0.68
1969 Richardson AG, Leach FR. Fractionation of competent Bacillus subtilis cells by sucrose density gradient centrifugation. Analytical Biochemistry. 27: 175-8. PMID 4990830  1
1969 Richardson AG, Pierson DL, Leach FR. The effect of phenethyl alcohol on Bacillus subtilis transformation. II. Transport of DNA and precursors. Biochimica Et Biophysica Acta. 174: 276-81. PMID 4974833  1
1969 Richardson AG, Leach FR. The effect of phenethyl alcohol on Bacillus subtilis transformation. I. Characterization of the effect. Biochimica Et Biophysica Acta. 174: 264-75. PMID 4974832  1
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