Arlan Richardson - Publications

Affiliations: 
The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States 
Area:
Animal Physiology Biology, Biostatistics Biology
Website:
http://www.ouhsc.edu/roca/OurPeople/ProfilePage/TabId/11561/ArtMID/30320/ArticleID/2185/ARLAN-RICHARDSON-PHD.aspx

203 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Thadathil N, Selvarani R, Mohammed S, Nicklas EH, Tran AL, Kamal M, Luo W, Brown JL, Lawrence MM, Borowik AK, Miller BF, Van Remmen H, Richardson A, Deepa SS. Senolytic treatment reduces cell senescence and necroptosis in Sod1 knockout mice that is associated with reduced inflammation and hepatocellular carcinoma. Aging Cell. PMID 35869934 DOI: 10.1111/acel.13676  0.335
2022 Guzman SD, Judge J, Shigdar SM, Paul TA, Davis CS, Macpherson PC, Markworth JF, Van Remmen H, Richardson A, McArdle A, Brooks SV. Removal of Expressing Cells in Late Life has Moderate Beneficial Effects on Skeletal Muscle Function in Male Mice. Frontiers in Aging. 2: 821904. PMID 35821997 DOI: 10.3389/fragi.2021.821904  0.323
2021 Unnikrishnan A, Matyi S, Garrett K, Ranjo-Bishop M, Allison DB, Ejima K, Chen X, Dickinson S, Richardson A. Reevaluation of the effect of dietary restriction on different recombinant inbred lines of male and female mice. Aging Cell. e13500. PMID 34713968 DOI: 10.1111/acel.13500  0.338
2021 Su Y, Claflin DR, Huang M, Davis CS, Macpherson PCD, Richardson A, Van Remmen H, Brooks SV. Deletion of Neuronal CuZnSOD Accelerates Age-Associated Muscle Mitochondria and Calcium Handling Dysfunction That Is Independent of Denervation and Precedes Sarcopenia. International Journal of Molecular Sciences. 22. PMID 34639076 DOI: 10.3390/ijms221910735  0.343
2021 Kurup K, Mann SN, Jackson J, Matyi S, Ranjo-Bishop M, Freeman WM, Stout MB, Richardson A, Unnikrishnan A. Litter expansion alters metabolic homeostasis in a sex specific manner. Plos One. 16: e0237199. PMID 34587168 DOI: 10.1371/journal.pone.0237199  0.347
2021 Thadathil N, Nicklas EH, Mohammed S, Lewis TL, Richardson A, Deepa SS. Necroptosis increases with age in the brain and contributes to age-related neuroinflammation. Geroscience. PMID 34515928 DOI: 10.1007/s11357-021-00448-5  0.319
2021 Mohammed S, Nicklas EH, Thadathil N, Selvarani R, Royce GH, Kinter M, Richardson A, Deepa SS. Role of necroptosis in chronic hepatic inflammation and fibrosis in a mouse model of increased oxidative stress. Free Radical Biology & Medicine. PMID 33429022 DOI: 10.1016/j.freeradbiomed.2020.12.449  0.348
2020 Brown JL, Lawrence MM, Ahn B, Kneis P, Piekarz KM, Qaisar R, Ranjit R, Bian J, Pharaoh G, Brown C, Peelor FF, Kinter MT, Miller BF, Richardson A, Van Remmen H. Cancer cachexia in a mouse model of oxidative stress. Journal of Cachexia, Sarcopenia and Muscle. PMID 32918528 DOI: 10.1002/Jcsm.12615  0.332
2020 Bhaskaran S, Pollock N, C Macpherson P, Ahn B, Piekarz KM, Staunton CA, Brown JL, Qaisar R, Vasilaki A, Richardson A, McArdle A, Jackson MJ, Brooks SV, Van Remmen H. Neuron-specific deletion of CuZnSOD leads to an advanced sarcopenic phenotype in older mice. Aging Cell. e13225. PMID 32886862 DOI: 10.1111/Acel.13225  0.453
2020 Richardson A. You Have Come A Long Way Baby: Five Decades of Research on the Biology of Aging from the Perspective of a Researcher Studying Aging. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 32840294 DOI: 10.1093/Gerona/Glaa208  0.325
2020 Pharaoh G, Brown JL, Sataranatarajan K, Kneis P, Bian J, Ranjit R, Hadad N, Georgescu C, Rabinovitch P, Ran Q, Wren JD, Freeman W, Kinter M, Richardson A, Van Remmen H. Targeting cPLA derived lipid hydroperoxides as a potential intervention for sarcopenia. Scientific Reports. 10: 13968. PMID 32811851 DOI: 10.1038/S41598-020-70792-7  0.351
2020 Jang YC, Rodriguez K, Lustgarten MS, Muller FL, Bhattacharya A, Pierce A, Choi JJ, Lee NH, Chaudhuri A, Richardson AG, Van Remmen H. Superoxide-mediated oxidative stress accelerates skeletal muscle atrophy by synchronous activation of proteolytic systems. Geroscience. PMID 32451848 DOI: 10.1007/s11357-020-00200-5  0.62
2020 Sataranatarajan K, Pharaoh G, Brown JL, Ranjit R, Piekarz KM, Street K, Wren JD, Georgescu C, Kinter C, Kinter M, Freeman WM, Richardson A, Van Remmen H. Molecular changes in transcription and metabolic pathways underlying muscle atrophy in the CuZnSOD null mouse model of sarcopenia. Geroscience. PMID 32394347 DOI: 10.1007/s11357-020-00189-x  0.352
2020 Carter CS, Richardson A, Huffman DM, Austad S. Bring Back the Rat! The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 31894235 DOI: 10.1093/Gerona/Glz298  0.315
2019 Unnikrishnan A, Kurup K, Salmon AB, Richardson A. Is Rapamycin a Dietary Restriction Mimetic? The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 30854544 DOI: 10.1093/Gerona/Glz060  0.387
2019 Ahn B, Ranjit R, Premkumar P, Pharaoh G, Piekarz KM, Matsuzaki S, Claflin DR, Riddle K, Judge J, Bhaskaran S, Satara Natarajan K, Barboza E, Wronowski B, Kinter M, Humphries KM, ... ... Richardson A, et al. Mitochondrial oxidative stress impairs contractile function but paradoxically increases muscle mass via fibre branching. Journal of Cachexia, Sarcopenia and Muscle. PMID 30706998 DOI: 10.1002/Jcsm.12375  0.336
2019 Deepa SS, Van Remmen H, Brooks SV, Faulkner JA, Larkin L, McArdle A, Jackson MJ, Vasilaki A, Richardson A. Accelerated sarcopenia in Cu/Zn superoxide dismutase knockout mice. Free Radical Biology & Medicine. 132: 19-23. PMID 30670156 DOI: 10.1016/J.Freeradbiomed.2018.06.032  0.435
2018 Unnikrishnan A, Freeman WM, Jackson J, Wren JD, Porter H, Richardson A. The role of DNA methylation in epigenetics of aging. Pharmacology & Therapeutics. PMID 30419258 DOI: 10.1016/J.Pharmthera.2018.11.001  0.329
2018 Qaisar R, Bhaskaran S, Premkumar P, Ranjit R, Natarajan KS, Ahn B, Riddle K, Claflin DR, Richardson A, Brooks SV, Van Remmen H. Oxidative stress-induced dysregulation of excitation-contraction coupling contributes to muscle weakness. Journal of Cachexia, Sarcopenia and Muscle. PMID 30073804 DOI: 10.1002/Jcsm.12339  0.503
2018 Deepa SS, Pharaoh G, Kinter M, Diaz V, Fok WC, Riddle K, Pulliam D, Hill S, Fischer KE, Soto V, Georgescu C, Wren JD, Viscomi C, Richardson A, Van Remmen H. Lifelong reduction in complex IV induces tissue-specific metabolic effects but does not reduce lifespan or healthspan in mice. Aging Cell. e12769. PMID 29696791 DOI: 10.1111/Acel.12769  0.489
2018 Deepa SS, Unnikrishnan A, Matyi S, Hadad N, Richardson A. Necroptosis increases with age and is reduced by dietary restriction. Aging Cell. e12770. PMID 29696779 DOI: 10.1111/Acel.12770  0.383
2018 Hadad N, Unnikrishnan A, Jackson JA, Masser DR, Otalora L, Stanford DR, Richardson A, Freeman WM. Caloric restriction mitigates age-associated hippocampal differential CG and non-CG methylation. Neurobiology of Aging. 67: 53-66. PMID 29631215 DOI: 10.1016/J.Neurobiolaging.2018.03.009  0.318
2018 Snider TA, Richardson A, Stoner JA, Deepa SS. The Geropathology Grading Platform demonstrates that mice null for Cu/Zn-superoxide dismutase show accelerated biological aging. Geroscience. PMID 29478190 DOI: 10.1007/s11357-018-0008-0  0.364
2017 Sakellariou G, McDonagh B, Porter H, Giakoumaki I, Earl K, Nye G, Vasilaki A, Brooks S, Richardson A, Van Remmen H, McArdle A, Jackson MJ. Comparison of whole body SOD1 knockout with muscle specific SOD1 knockout mice reveals a role for nerve redox signaling in regulation of degenerative pathways in skeletal muscle. Antioxidants & Redox Signaling. PMID 29065712 DOI: 10.1089/Ars.2017.7249  0.427
2017 Vasilaki A, Richardson A, Van Remmen H, Brooks SV, Larkin L, McArdle A, Jackson MJ. Role of nerve-muscle interactions and ROS in regulation of muscle proteostasis with aging. The Journal of Physiology. PMID 28792061 DOI: 10.1113/Jp274336  0.34
2017 Unnikrishnan A, Jackson J, Matyi SA, Hadad N, Wronowski B, Georgescu C, Garrett KP, Wren JD, Freeman WM, Richardson A. Role of DNA methylation in the dietary restriction mediated cellular memory. Geroscience. PMID 28477138 DOI: 10.1007/S11357-017-9976-8  0.302
2017 Deepa SS, Bhaskaran S, Espinoza S, Brooks SV, McArdle A, Jackson MJ, Van Remmen H, Richardson A. A new mouse model of frailty: the Cu/Zn superoxide dismutase knockout mouse. Geroscience. PMID 28409332 DOI: 10.1007/S11357-017-9975-9  0.473
2017 Bhaskaran S, Li H, Ahn B, Piekarz K, Ranjit R, Qaisar R, Premkumar P, Pharaoh G, Forbes B, Riddle K, Richardson A, Remmen HV. Inducible motor neuron specific deletion of CuZn Superoxide dismutase accelerates muscle atrophy in mice Free Radical Biology and Medicine. 112: 48-49. DOI: 10.1016/J.Freeradbiomed.2017.10.063  0.458
2017 Ahn B, Ranjit R, Matsuzaki S, Premkumar P, Pharaoh G, Riddle K, Wronowski B, Kinter M, Humphries K, Freeman W, Richardson A, Remmen HV. MnSod deficiency causes significant mitochondrial abnormalities and contractile dysfunction in skeletal muscle, but does not decrease muscle mass Free Radical Biology and Medicine. 112: 48. DOI: 10.1016/J.Freeradbiomed.2017.10.062  0.428
2016 Etzler JC, Bollo M, Holstein D, Deng JJ, Perez V, Lin DT, Richardson A, Bai Y, Lechleiter JD. Cyclophilin D over-expression increases mitochondrial complex III activity and accelerates supercomplex formation. Archives of Biochemistry and Biophysics. PMID 27916505 DOI: 10.1016/J.Abb.2016.11.008  0.349
2016 Zhang Y, Unnikrishnan A, Deepa SS, Liu Y, Li Y, Ikeno Y, Sosnowska D, Van Remmen H, Richardson A. A new role for oxidative stress in aging: The accelerated aging phenotype in Sod1(-/)(-) mice is correlated to increased cellular senescence. Redox Biology. 11: 30-37. PMID 27846439 DOI: 10.1016/J.Redox.2016.10.014  0.517
2016 Salmon AB, Kim G, Liu C, Wren JD, Georgescu C, Richardson A, Levine RL. Effects of transgenic methionine sulfoxide reductase A (MsrA) expression on lifespan and age-dependent changes in metabolic function in mice. Redox Biology. 10: 251-256. PMID 27821326 DOI: 10.1016/J.Redox.2016.10.012  0.516
2016 Hadad N, Masser DR, Logan S, Wronowski B, Mangold CA, Clark N, Otalora L, Unnikrishnan A, Ford MM, Giles CB, Wren JD, Richardson A, Sonntag WE, Stanford DR, Freeman W. Absence of genomic hypomethylation or regulation of cytosine-modifying enzymes with aging in male and female mice. Epigenetics & Chromatin. 9: 30. PMID 27413395 DOI: 10.1186/S13072-016-0080-6  0.34
2016 Lin AL, Butterfield DA, Richardson A. mTOR: Alzheimer's disease prevention for APOE4 carriers. Oncotarget. PMID 27385004 DOI: 10.18632/Oncotarget.10349  0.371
2016 Strong R, Miller RA, Antebi A, Astle CM, Bogue M, Denzel MS, Fernandez E, Flurkey K, Hamilton KL, Lamming DW, Javors MA, de Magalhães JP, Marinez PA, McCord JM, Miller BF, ... ... Richardson A, et al. Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer. Aging Cell. PMID 27312235 DOI: 10.1111/Acel.12496  0.33
2016 Richardson A, Pedley G, Pelone F, Akhtar F, Chang J, Muleya W, Greenwood N. Psychosocial interventions for people with young onset dementia and their carers: a systematic review. International Psychogeriatrics / Ipa. 1-14. PMID 27072752 DOI: 10.1017/S1041610216000132  0.435
2016 Zhang Y, Liu Y, Walsh M, Bokov A, Ikeno Y, Jang YC, Perez VI, Van Remmen H, Richardson A. Liver specific expression of Cu/ZnSOD extends the lifespan of Sod1 null mice. Mechanisms of Ageing and Development. PMID 26839948 DOI: 10.1016/J.Mad.2016.01.005  0.823
2016 Fritsche LG, Igl W, Bailey JN, Grassmann F, Sengupta S, Bragg-Gresham JL, Burdon KP, Hebbring SJ, Wen C, Gorski M, Kim IK, Cho D, Zack D, Souied E, Scholl HP, ... ... Richardson AJ, et al. A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants. Nature Genetics. 48: 134-43. PMID 26691988 DOI: 10.1038/Ng.3448  0.478
2015 Lin AL, Jahrling JB, Zhang W, DeRosa N, Bakshi V, Romero P, Galvan V, Richardson A. Rapamycin rescues vascular, metabolic and learning deficits in apolipoprotein E4 transgenic mice with pre-symptomatic Alzheimer's disease. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 26721390 DOI: 10.1177/0271678X15621575  0.324
2015 McAtee PA, Richardson AC, Nieuwenhuizen NJ, Gunaseelan K, Hoong L, Chen X, Atkinson RG, Burdon JN, David KM, Schaffer RJ. The hybrid non-ethylene and ethylene ripening response in kiwifruit (Actinidia chinensis) is associated with differential regulation of MADS-box transcription factors. Bmc Plant Biology. 15: 304. PMID 26714876 DOI: 10.1186/s12870-015-0697-9  0.44
2015 Hunnicut J, Liu Y, Richardson A, Salmon AB. MsrA Overexpression Targeted to the Mitochondria, but Not Cytosol, Preserves Insulin Sensitivity in Diet-Induced Obese Mice. Plos One. 10: e0139844. PMID 26448611 DOI: 10.1371/Journal.Pone.0139844  0.409
2015 Sataranatarajan K, Ikeno Y, Bokov A, Feliers D, Yalamanchili H, Lee HJ, Mariappan MM, Tabatabai-Mir H, Diaz V, Prasad S, Javors MA, Ghosh Choudhury G, Hubbard GB, Barnes JL, Richardson A, et al. Rapamycin Increases Mortality in db/db Mice, a Mouse Model of Type 2 Diabetes. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 26442901 DOI: 10.1093/Gerona/Glv170  0.735
2015 Richardson A, Fischer KE, Speakman JR, de Cabo R, Mitchell SJ, Peterson CA, Rabinovitch P, Chiao YA, Taffet G, Miller RA, Rentería RC, Bower J, Ingram DK, Ladiges WC, Ikeno Y, et al. Measures of Healthspan as Indices of Aging in Mice-A Recommendation. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 26297941 DOI: 10.1093/Gerona/Glv080  0.329
2015 Sataranatarajan K, Qaisar R, Davis C, Sakellariou GK, Vasilaki A, Zhang Y, Liu Y, Bhaskaran S, McArdle A, Jackson M, Brooks SV, Richardson A, Van Remmen H. Neuron specific reduction in CuZnSOD is not sufficient to initiate a full sarcopenia phenotype. Redox Biology. 5: 140-148. PMID 25917273 DOI: 10.1016/J.Redox.2015.04.005  0.444
2015 Calhoun C, Shivshankar P, Saker M, Sloane LB, Livi CB, Sharp ZD, Orihuela CJ, Adnot S, White ES, Richardson A, Jourdan Le Saux C. Senescent Cells Contribute to the Physiological Remodeling of Aged Lungs. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 25568097 DOI: 10.1093/Gerona/Glu241  0.365
2015 Zhang Y, Fischer KE, Soto V, Liu Y, Sosnowska D, Richardson A, Salmon AB. Obesity-induced oxidative stress, accelerated functional decline with age and increased mortality in mice. Archives of Biochemistry and Biophysics. 576: 39-48. PMID 25558793 DOI: 10.1016/J.Abb.2014.12.018  0.398
2015 Richardson A, Galvan V, Lin AL, Oddo S. How longevity research can lead to therapies for Alzheimer's disease: The rapamycin story. Experimental Gerontology. 68: 51-8. PMID 25481271 DOI: 10.1016/J.Exger.2014.12.002  0.342
2015 Kwak HB, Lee Y, Kim JH, Van Remmen H, Richardson AG, Lawler JM. MnSOD overexpression reduces fibrosis and pro-apoptotic signaling in the aging mouse heart. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 70: 533-44. PMID 25016531 DOI: 10.1093/gerona/glu090  0.35
2014 Walsh ME, Sloane LB, Fischer KE, Austad SN, Richardson A, Van Remmen H. Use of Nerve Conduction Velocity to Assess Peripheral Nerve Health in Aging Mice. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 25477428 DOI: 10.1093/Gerona/Glu208  0.364
2014 Fok WC, Livi C, Bokov A, Yu Z, Chen Y, Richardson A, Pérez VI. Short-term rapamycin treatment in mice has few effects on the transcriptome of white adipose tissue compared to dietary restriction. Mechanisms of Ageing and Development. 140: 23-9. PMID 25075714 DOI: 10.1016/J.Mad.2014.07.004  0.73
2014 Fok WC, Chen Y, Bokov A, Zhang Y, Salmon AB, Diaz V, Javors M, Wood WH, Zhang Y, Becker KG, Pérez VI, Richardson A. Mice fed rapamycin have an increase in lifespan associated with major changes in the liver transcriptome. Plos One. 9: e83988. PMID 24409289 DOI: 10.1371/Journal.Pone.0083988  0.72
2014 Sakellariou GK, Davis CS, Shi Y, Ivannikov MV, Zhang Y, Vasilaki A, Macleod GT, Richardson A, Van Remmen H, Jackson MJ, McArdle A, Brooks SV. Neuron-specific expression of CuZnSOD prevents the loss of muscle mass and function that occurs in homozygous CuZnSOD-knockout mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 1666-81. PMID 24378874 DOI: 10.1096/Fj.13-240390  0.478
2014 Fok WC, Bokov A, Gelfond J, Yu Z, Zhang Y, Doderer M, Chen Y, Javors M, Wood WH, Zhang Y, Becker KG, Richardson A, Pérez VI. Combined treatment of rapamycin and dietary restriction has a larger effect on the transcriptome and metabolome of liver. Aging Cell. 13: 311-9. PMID 24304444 DOI: 10.1111/Acel.12175  0.718
2014 Zhang Y, Bokov A, Gelfond J, Soto V, Ikeno Y, Hubbard G, Diaz V, Sloane L, Maslin K, Treaster S, Réndon S, van Remmen H, Ward W, Javors M, Richardson A, et al. Rapamycin extends life and health in C57BL/6 mice. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 69: 119-30. PMID 23682161 DOI: 10.1093/Gerona/Glt056  0.722
2014 Liu Y, Zhang Y, Soto V, Diaz V, Fischer K, Richardson A, Salmon A. Evidence for Obesity-Induced Acceleration of Aging Mediated by Oxidative Stress Free Radical Biology and Medicine. 76. DOI: 10.1016/J.Freeradbiomed.2014.10.460  0.342
2013 Liu Y, Qi W, Richardson A, Van Remmen H, Ikeno Y, Salmon AB. Oxidative damage associated with obesity is prevented by overexpression of CuZn- or Mn-superoxide dismutase. Biochemical and Biophysical Research Communications. 438: 78-83. PMID 23872067 DOI: 10.1016/J.Bbrc.2013.07.029  0.44
2013 Lin AL, Pulliam DA, Deepa SS, Halloran JJ, Hussong SA, Burbank RR, Bresnen A, Liu Y, Podlutskaya N, Soundararajan A, Muir E, Duong TQ, Bokov AF, Viscomi C, Zeviani M, ... Richardson AG, et al. Decreased in vitro mitochondrial function is associated with enhanced brain metabolism, blood flow, and memory in Surf1-deficient mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 1605-11. PMID 23838831 DOI: 10.1038/Jcbfm.2013.116  0.715
2013 Zhang Y, Davis C, Sakellariou GK, Shi Y, Kayani AC, Pulliam D, Bhattacharya A, Richardson A, Jackson MJ, McArdle A, Brooks SV, Van Remmen H. CuZnSOD gene deletion targeted to skeletal muscle leads to loss of contractile force but does not cause muscle atrophy in adult mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 3536-48. PMID 23729587 DOI: 10.1096/Fj.13-228130  0.402
2013 Zhang Y, Ikeno Y, Bokov A, Gelfond J, Jaramillo C, Zhang HM, Liu Y, Qi W, Hubbard G, Richardson A, Van Remmen H. Dietary restriction attenuates the accelerated aging phenotype of Sod1(-/-) mice. Free Radical Biology & Medicine. 60: 300-6. PMID 23459073 DOI: 10.1016/J.Freeradbiomed.2013.02.026  0.778
2013 Styskal J, Nwagwu FA, Watkins YN, Liang H, Richardson A, Musi N, Salmon AB. Methionine sulfoxide reductase A affects insulin resistance by protecting insulin receptor function. Free Radical Biology & Medicine. 56: 123-32. PMID 23089224 DOI: 10.1016/J.Freeradbiomed.2012.10.544  0.584
2013 Fok WC, Zhang Y, Salmon AB, Bhattacharya A, Gunda R, Jones D, Ward W, Fisher K, Richardson A, Pérez VI. Short-term treatment with rapamycin and dietary restriction have overlapping and distinctive effects in young mice. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 68: 108-16. PMID 22570137 DOI: 10.1093/Gerona/Gls127  0.414
2013 Salmon A, Liu R, Pulliam D, Richardson A. PSS262 - Depot-Specific Patterns in Adipose Tissue Oxidative Stress and Dysfunction during Aging Free Radical Biology and Medicine. 65. DOI: 10.1016/J.Freeradbiomed.2013.10.685  0.351
2012 Sataranatarajan K, Feliers D, Mariappan MM, Lee HJ, Lee MJ, Day RT, Yalamanchili HB, Choudhury GG, Barnes JL, Van Remmen H, Richardson A, Kasinath BS. Molecular events in matrix protein metabolism in the aging kidney. Aging Cell. 11: 1065-73. PMID 23020145 DOI: 10.1111/Acel.12008  0.328
2012 Salmon AB, Flores LC, Li Y, Van Remmen H, Richardson A, Ikeno Y. Reduction of glucose intolerance with high fat feeding is associated with anti-inflammatory effects of thioredoxin 1 overexpression in mice. Pathobiology of Aging & Age Related Diseases. 2. PMID 22953037 DOI: 10.3402/pba.v2i0.17101  0.321
2012 Tabatabai-Mir H, Sataranatarajan K, Lee HJ, Bokov AF, Fernandez E, Diaz V, Choudhury GG, Richardson A, Kasinath BS. Rapamycin selectively alters serum chemistry in diabetic mice. Pathobiology of Aging & Age Related Diseases. 2. PMID 22953036 DOI: 10.3402/pba.v2i0.15896  0.695
2012 Charchaflieh J, Labaze GI, Li P, Van Remmen H, Lee H, Stutz H, Richardson A, Emanuel A, Zhang M. Overexpression of human SOD1 improves survival of mice susceptible to endotoxic shock. Journal of Inflammation Research. 5: 51-8. PMID 22879777 DOI: 10.2147/Jir.S32073  0.346
2012 Halloran J, Hussong SA, Burbank R, Podlutskaya N, Fischer KE, Sloane LB, Austad SN, Strong R, Richardson A, Hart MJ, Galvan V. Chronic inhibition of mammalian target of rapamycin by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice. Neuroscience. 223: 102-13. PMID 22750207 DOI: 10.1016/J.Neuroscience.2012.06.054  0.4
2012 Jang YC, Liu Y, Hayworth CR, Bhattacharya A, Lustgarten MS, Muller FL, Chaudhuri A, Qi W, Li Y, Huang JY, Verdin E, Richardson A, Van Remmen H. Dietary restriction attenuates age-associated muscle atrophy by lowering oxidative stress in mice even in complete absence of CuZnSOD. Aging Cell. 11: 770-82. PMID 22672615 DOI: 10.1111/J.1474-9726.2012.00843.X  0.686
2012 Lustgarten MS, Bhattacharya A, Muller FL, Jang YC, Shimizu T, Shirasawa T, Richardson A, Van Remmen H. Complex I generated, mitochondrial matrix-directed superoxide is released from the mitochondria through voltage dependent anion channels. Biochemical and Biophysical Research Communications. 422: 515-21. PMID 22613204 DOI: 10.1016/J.Bbrc.2012.05.055  0.779
2012 Lamming DW, Ye L, Katajisto P, Goncalves MD, Saitoh M, Stevens DM, Davis JG, Salmon AB, Richardson A, Ahima RS, Guertin DA, Sabatini DM, Baur JA. Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity. Science (New York, N.Y.). 335: 1638-43. PMID 22461615 DOI: 10.1126/Science.1215135  0.303
2012 Yoo SE, Chen L, Na R, Liu Y, Rios C, Van Remmen H, Richardson A, Ran Q. Gpx4 ablation in adult mice results in a lethal phenotype accompanied by neuronal loss in brain. Free Radical Biology & Medicine. 52: 1820-7. PMID 22401858 DOI: 10.1016/J.Freeradbiomed.2012.02.043  0.386
2012 Majumder S, Caccamo A, Medina DX, Benavides AD, Javors MA, Kraig E, Strong R, Richardson A, Oddo S. Lifelong rapamycin administration ameliorates age-dependent cognitive deficits by reducing IL-1β and enhancing NMDA signaling. Aging Cell. 11: 326-35. PMID 22212527 DOI: 10.1111/J.1474-9726.2011.00791.X  0.354
2012 Styskal J, Van Remmen H, Richardson A, Salmon AB. Oxidative stress and diabetes: what can we learn about insulin resistance from antioxidant mutant mouse models? Free Radical Biology & Medicine. 52: 46-58. PMID 22056908 DOI: 10.1016/J.Freeradbiomed.2011.10.441  0.378
2012 Bhattacharya A, Bokov A, Muller FL, Jernigan AL, Maslin K, Diaz V, Richardson A, Van Remmen H. Dietary restriction but not rapamycin extends disease onset and survival of the H46R/H48Q mouse model of ALS. Neurobiology of Aging. 33: 1829-32. PMID 21763036 DOI: 10.1016/J.Neurobiolaging.2011.06.002  0.764
2011 Bokov AF, Garg N, Ikeno Y, Thakur S, Musi N, DeFronzo RA, Zhang N, Erickson RC, Gelfond J, Hubbard GB, Adamo ML, Richardson A. Does reduced IGF-1R signaling in Igf1r+/- mice alter aging? Plos One. 6: e26891. PMID 22132081 DOI: 10.1371/Journal.Pone.0026891  0.739
2011 Liang H, Ward WF, Jang YC, Bhattacharya A, Bokov AF, Li Y, Jernigan A, Richardson A, Van Remmen H. PGC-1α protects neurons and alters disease progression in an amyotrophic lateral sclerosis mouse model. Muscle & Nerve. 44: 947-56. PMID 22102466 DOI: 10.1002/Mus.22217  0.798
2011 Larkin LM, Davis CS, Sims-Robinson C, Kostrominova TY, Van Remmen H, Richardson A, Feldman EL, Brooks SV. Skeletal muscle weakness due to deficiency of CuZn-superoxide dismutase is associated with loss of functional innervation. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 301: R1400-7. PMID 21900648 DOI: 10.1152/Ajpregu.00093.2011  0.448
2011 Pérez VI, Cortez LA, Lew CM, Rodriguez M, Webb CR, Van Remmen H, Chaudhuri A, Qi W, Lee S, Bokov A, Fok W, Jones D, Richardson A, Yodoi J, Zhang Y, et al. Thioredoxin 1 overexpression extends mainly the earlier part of life span in mice. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 66: 1286-99. PMID 21873593 DOI: 10.1093/Gerona/Glr125  0.777
2011 Ghosh S, Lertwattanarak R, Lefort N, Molina-Carrion M, Joya-Galeana J, Bowen BP, Garduno-Garcia Jde J, Abdul-Ghani M, Richardson A, DeFronzo RA, Mandarino L, Van Remmen H, Musi N. Reduction in reactive oxygen species production by mitochondria from elderly subjects with normal and impaired glucose tolerance. Diabetes. 60: 2051-60. PMID 21677280 DOI: 10.2337/Db11-0121  0.33
2011 Bhattacharya A, Leonard S, Tardif S, Buffenstein R, Fischer KE, Richardson A, Austad SN, Chaudhuri AR. Attenuation of liver insoluble protein carbonyls: indicator of a longevity determinant? Aging Cell. 10: 720-3. PMID 21463461 DOI: 10.1111/J.1474-9726.2011.00712.X  0.363
2011 Sakellariou GK, Pye D, Vasilaki A, Zibrik L, Palomero J, Kabayo T, McArdle F, Van Remmen H, Richardson A, Tidball JG, McArdle A, Jackson MJ. Role of superoxide-nitric oxide interactions in the accelerated age-related loss of muscle mass in mice lacking Cu,Zn superoxide dismutase. Aging Cell. 10: 749-60. PMID 21443684 DOI: 10.1111/J.1474-9726.2011.00709.X  0.443
2011 Sharp ZD, Richardson A. Aging and cancer: can mTOR inhibitors kill two birds with one drug? Targeted Oncology. 6: 41-51. PMID 21394528 DOI: 10.1007/S11523-011-0168-7  0.33
2011 Lustgarten MS, Jang YC, Liu Y, Qi W, Qin Y, Dahia PL, Shi Y, Bhattacharya A, Muller FL, Shimizu T, Shirasawa T, Richardson A, Van Remmen H. MnSOD deficiency results in elevated oxidative stress and decreased mitochondrial function but does not lead to muscle atrophy during aging. Aging Cell. 10: 493-505. PMID 21385310 DOI: 10.1111/J.1474-9726.2011.00695.X  0.835
2011 Sun LY, Bokov AF, Richardson A, Miller RA. Hepatic response to oxidative injury in long-lived Ames dwarf mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 398-408. PMID 20826540 DOI: 10.1096/Fj.10-164376  0.759
2011 Robbins DF, VanRemmen H, Richardson A, Wang DB, Witt SN, Klein RL, Zhao Y, Wittwer JA, Wang F, Codarin S, Shen X, Kevil CG, Circu ML, Aw TY, Huang TT. Abstract B59: Targeting metabolic enzymes in cancer prevention: Mechanistic insight into reciprocal regulation of isoforms of pyruvate kinase and isocitrate dehydrogenase in the early stage of cancer development Cancer Prevention Research. 4. DOI: 10.1158/1940-6207.Prev-11-B59  0.323
2011 Salmon A, Remmen HV, Pulliam D, Liu Y, Styskal J, Bhattacharya A, Kim G, Zhao H, Levine R, Richardson A. Mitochondria-Generated Oxidative Stress is Altered by Subcellular Localization of MsrA Overexpression Free Radical Biology and Medicine. 51. DOI: 10.1016/J.Freeradbiomed.2011.10.297  0.356
2011 Steinbaugh MJ, Sun LY, Bokov AF, Richardson A, Miller RA. Stress kinases: Altered in fibroblasts and liver of dwarf mice Experimental Gerontology. 46: 210. DOI: 10.1016/J.Exger.2010.11.019  0.731
2010 Pierce A, Wei R, Halade D, Yoo SE, Ran Q, Richardson A. A Novel mouse model of enhanced proteostasis: Full-length human heat shock factor 1 transgenic mice. Biochemical and Biophysical Research Communications. 402: 59-65. PMID 20920476 DOI: 10.1016/J.Bbrc.2010.09.111  0.392
2010 Vasilaki A, van der Meulen JH, Larkin L, Harrison DC, Pearson T, Van Remmen H, Richardson A, Brooks SV, Jackson MJ, McArdle A. The age-related failure of adaptive responses to contractile activity in skeletal muscle is mimicked in young mice by deletion of Cu,Zn superoxide dismutase. Aging Cell. 9: 979-90. PMID 20883524 DOI: 10.1111/J.1474-9726.2010.00635.X  0.462
2010 Pérez VI, Pierce A, de Waal EM, Ward WF, Bokov A, Chaudhuri A, Richardson A. Detection and quantification of protein disulfides in biological tissues a fluorescence-based proteomic approach. Methods in Enzymology. 473: 161-77. PMID 20513477 DOI: 10.1016/S0076-6879(10)73008-1  0.704
2010 Khodr CE, Clark S, Bokov AF, Richardson A, Strong R, Hurley DL, Phelps CJ. Early postnatal administration of growth hormone increases tuberoinfundibular dopaminergic neuron numbers in Ames dwarf mice. Endocrinology. 151: 3277-85. PMID 20463054 DOI: 10.1210/En.2009-1482  0.69
2010 Spilman P, Podlutskaya N, Hart MJ, Debnath J, Gorostiza O, Bredesen D, Richardson A, Strong R, Galvan V. Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-β levels in a mouse model of alzheimer's disease Plos One. 5. PMID 20376313 DOI: 10.1371/Journal.Pone.0009979  0.332
2010 Jang YC, Lustgarten MS, Liu Y, Muller FL, Bhattacharya A, Liang H, Salmon AB, Brooks SV, Larkin L, Hayworth CR, Richardson A, Van Remmen H. Increased superoxide in vivo accelerates age-associated muscle atrophy through mitochondrial dysfunction and neuromuscular junction degeneration. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 1376-90. PMID 20040516 DOI: 10.1096/Fj.09-146308  0.822
2010 Salmon AB, Richardson A, Pérez VI. Update on the oxidative stress theory of aging: does oxidative stress play a role in aging or healthy aging? Free Radical Biology & Medicine. 48: 642-55. PMID 20036736 DOI: 10.1016/J.Freeradbiomed.2009.12.015  0.414
2010 McClung JM, Deruisseau KC, Whidden MA, Van Remmen H, Richardson A, Song W, Vrabas IS, Powers SK. Overexpression of antioxidant enzymes in diaphragm muscle does not alter contraction-induced fatigue or recovery. Experimental Physiology. 95: 222-31. PMID 19783618 DOI: 10.1113/Expphysiol.2009.049650  0.359
2010 Cortez LA, Webb CR, Mahlke M, Bhattacharya A, Qi W, Zhang Y, Liu Y, Lee S, VanRemmen H, Richardson A, Tominaga K, Ikeno Y. Do Thioredoxin 2 Transgenic and Thioredoxin 1 Knockout Mice Extend Lifespan through Different Mechanisms? Free Radical Biology and Medicine. 49: S80-S81. DOI: 10.1016/J.Freeradbiomed.2010.10.202  0.447
2009 Lustgarten MS, Jang YC, Liu Y, Muller FL, Qi W, Steinhelper M, Brooks SV, Larkin L, Shimizu T, Shirasawa T, McManus LM, Bhattacharya A, Richardson A, Van Remmen H. Conditional knockout of Mn-SOD targeted to type IIB skeletal muscle fibers increases oxidative stress and is sufficient to alter aerobic exercise capacity. American Journal of Physiology. Cell Physiology. 297: C1520-32. PMID 19776389 DOI: 10.1152/Ajpcell.00372.2009  0.813
2009 Zhang Y, Ikeno Y, Qi W, Chaudhuri A, Li Y, Bokov A, Thorpe SR, Baynes JW, Epstein C, Richardson A, Van Remmen H. Mice deficient in both Mn superoxide dismutase and glutathione peroxidase-1 have increased oxidative damage and a greater incidence of pathology but no reduction in longevity. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 64: 1212-20. PMID 19776219 DOI: 10.1093/Gerona/Glp132  0.786
2009 Liang H, Yoo SE, Na R, Walter CA, Richardson A, Ran Q. Short form glutathione peroxidase 4 is the essential isoform required for survival and somatic mitochondrial functions. The Journal of Biological Chemistry. 284: 30836-44. PMID 19744930 DOI: 10.1074/Jbc.M109.032839  0.61
2009 Jang YC, Pérez VI, Song W, Lustgarten MS, Salmon AB, Mele J, Qi W, Liu Y, Liang H, Chaudhuri A, Ikeno Y, Epstein CJ, Van Remmen H, Richardson A. Overexpression of Mn superoxide dismutase does not increase life span in mice. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 64: 1114-25. PMID 19633237 DOI: 10.1093/Gerona/Glp100  0.825
2009 Bokov AF, Ko D, Richardson A. The effect of gonadectomy and estradiol on sensitivity to oxidative stress. Endocrine Research. 34: 43-58. PMID 19557590 DOI: 10.1080/07435800902913600  0.732
2009 Pérez VI, Bokov A, Van Remmen H, Mele J, Ran Q, Ikeno Y, Richardson A. Is the oxidative stress theory of aging dead? Biochimica Et Biophysica Acta. 1790: 1005-14. PMID 19524016 DOI: 10.1016/J.Bbagen.2009.06.003  0.809
2009 Salmon AB, Pérez VI, Bokov A, Jernigan A, Kim G, Zhao H, Levine RL, Richardson A. Lack of methionine sulfoxide reductase A in mice increases sensitivity to oxidative stress but does not diminish life span. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 3601-8. PMID 19487311 DOI: 10.1096/Fj.08-127415  0.776
2009 Ladiges W, Van Remmen H, Strong R, Ikeno Y, Treuting P, Rabinovitch P, Richardson A. Lifespan extension in genetically modified mice. Aging Cell. 8: 346-52. PMID 19485964 DOI: 10.1111/J.1474-9726.2009.00491.X  0.379
2009 Liang H, Ran Q, Jang YC, Holstein D, Lechleiter J, McDonald-Marsh T, Musatov A, Song W, Van Remmen H, Richardson A. Glutathione peroxidase 4 differentially regulates the release of apoptogenic proteins from mitochondria. Free Radical Biology & Medicine. 47: 312-20. PMID 19447173 DOI: 10.1016/J.Freeradbiomed.2009.05.012  0.826
2009 Bokov AF, Lindsey ML, Khodr C, Sabia MR, Richardson A. Long-lived ames dwarf mice are resistant to chemical stressors. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 64: 819-27. PMID 19414510 DOI: 10.1093/Gerona/Glp052  0.755
2009 Salmon AB, Leonard S, Masamsetti V, Pierce A, Podlutsky AJ, Podlutskaya N, Richardson A, Austad SN, Chaudhuri AR. The long lifespan of two bat species is correlated with resistance to protein oxidation and enhanced protein homeostasis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 2317-26. PMID 19244163 DOI: 10.1096/Fj.08-122523  0.422
2009 Pérez VI, Buffenstein R, Masamsetti V, Leonard S, Salmon AB, Mele J, Andziak B, Yang T, Edrey Y, Friguet B, Ward W, Richardson A, Chaudhuri A. Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat. Proceedings of the National Academy of Sciences of the United States of America. 106: 3059-64. PMID 19223593 DOI: 10.1073/Pnas.0809620106  0.718
2009 Liang H, Balas B, Tantiwong P, Dube J, Goodpaster BH, O'Doherty RM, DeFronzo RA, Richardson A, Musi N, Ward WF. Whole body overexpression of PGC-1alpha has opposite effects on hepatic and muscle insulin sensitivity. American Journal of Physiology. Endocrinology and Metabolism. 296: E945-54. PMID 19208857 DOI: 10.1152/Ajpendo.90292.2008  0.521
2009 Pérez VI, Van Remmen H, Bokov A, Epstein CJ, Vijg J, Richardson A. The overexpression of major antioxidant enzymes does not extend the lifespan of mice. Aging Cell. 8: 73-5. PMID 19077044 DOI: 10.1111/J.1474-9726.2008.00449.X  0.755
2009 Larosche I, Choumar A, Fromenty B, Lettéron P, Abbey-Toby A, Van Remmen H, Epstein CJ, Richardson A, Feldmann G, Pessayre D, Mansouri A. Prolonged ethanol administration depletes mitochondrial DNA in MnSOD-overexpressing transgenic mice, but not in their wild type littermates. Toxicology and Applied Pharmacology. 234: 326-38. PMID 19063909 DOI: 10.1016/J.Taap.2008.11.004  0.446
2008 Chen L, Na R, Gu M, Salmon AB, Liu Y, Liang H, Qi W, Van Remmen H, Richardson A, Ran Q. Reduction of mitochondrial H2O2 by overexpressing peroxiredoxin 3 improves glucose tolerance in mice. Aging Cell. 7: 866-78. PMID 18778410 DOI: 10.1111/J.1474-9726.2008.00432.X  0.655
2008 Muller FL, Liu Y, Jernigan A, Borchelt D, Richardson A, Van Remmen H. MnSOD deficiency has a differential effect on disease progression in two different ALS mutant mouse models Muscle and Nerve. 38: 1173-1183. PMID 18720509 DOI: 10.1002/Mus.21049  0.629
2008 Pierce A, Mirzaei H, Muller F, De Waal E, Taylor AB, Leonard S, Van Remmen H, Regnier F, Richardson A, Chaudhuri A. GAPDH is conformationally and functionally altered in association with oxidative stress in mouse models of amyotrophic lateral sclerosis. Journal of Molecular Biology. 382: 1195-210. PMID 18706911 DOI: 10.1016/J.Jmb.2008.07.088  0.596
2008 Chen L, Na R, Gu M, Richardson A, Ran Q. Lipid peroxidation up-regulates BACE1 expression in vivo: a possible early event of amyloidogenesis in Alzheimer's disease. Journal of Neurochemistry. 107: 197-207. PMID 18680556 DOI: 10.1111/J.1471-4159.2008.05603.X  0.428
2008 Han ES, Muller FL, Pérez VI, Qi W, Liang H, Xi L, Fu C, Doyle E, Hickey M, Cornell J, Epstein CJ, Roberts LJ, Van Remmen H, Richardson A. The in vivo gene expression signature of oxidative stress. Physiological Genomics. 34: 112-26. PMID 18445702 DOI: 10.1152/Physiolgenomics.00239.2007  0.753
2008 Pérez VI, Lew CM, Cortez LA, Webb CR, Rodriguez M, Liu Y, Qi W, Li Y, Chaudhuri A, Van Remmen H, Richardson A, Ikeno Y. Thioredoxin 2 haploinsufficiency in mice results in impaired mitochondrial function and increased oxidative stress. Free Radical Biology & Medicine. 44: 882-92. PMID 18164269 DOI: 10.1016/J.Freeradbiomed.2007.11.018  0.52
2007 Vasilaki A, Simpson D, McArdle F, McLean L, Beynon RJ, Van Remmen H, Richardson AG, McArdle A, Faulkner JA, Jackson MJ. Formation of 3-nitrotyrosines in carbonic anhydrase III is a sensitive marker of oxidative stress in skeletal muscle. Proteomics. Clinical Applications. 1: 362-72. PMID 21136689 DOI: 10.1002/Prca.200600702  0.377
2007 Ran Q, Liang H, Ikeno Y, Qi W, Prolla TA, Roberts LJ, Wolf N, Van Remmen H, VanRemmen H, Richardson A. Reduction in glutathione peroxidase 4 increases life span through increased sensitivity to apoptosis. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 62: 932-42. PMID 17895430 DOI: 10.1093/Gerona/62.9.932  0.662
2007 Muller FL, Lustgarten MS, Jang Y, Richardson A, Van Remmen H. Trends in oxidative aging theories. Free Radical Biology & Medicine. 43: 477-503. PMID 17640558 DOI: 10.1016/J.Freeradbiomed.2007.03.034  0.804
2007 Muller FL, Song W, Jang YC, Liu Y, Sabia M, Richardson A, Van Remmen H. Denervation-induced skeletal muscle atrophy is associated with increased mitochondrial ROS production. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 293: R1159-68. PMID 17584954 DOI: 10.1152/Ajpregu.00767.2006  0.804
2007 Liang H, Bai Y, Li Y, Richardson A, Ward WF. PGC-1alpha-induced mitochondrial alterations in 3T3 fibroblast cells. Annals of the New York Academy of Sciences. 1100: 264-79. PMID 17460188 DOI: 10.1196/annals.1395.028  0.529
2007 Liang H, Van Remmen H, Frohlich V, Lechleiter J, Richardson A, Ran Q. Gpx4 protects mitochondrial ATP generation against oxidative damage. Biochemical and Biophysical Research Communications. 356: 893-8. PMID 17395155 DOI: 10.1016/J.Bbrc.2007.03.045  0.665
2007 Chang J, Cornell JE, Van Remmen H, Hakala K, Ward WF, Richardson A. Effect of aging and caloric restriction on the mitochondrial proteome. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 62: 223-34. PMID 17389719 DOI: 10.1093/Ehjci/Jet223  0.59
2007 Zhang Y, Padalecki SS, Chaudhuri AR, De Waal E, Goins BA, Grubbs B, Ikeno Y, Richardson A, Mundy GR, Herman B. Caspase-2 deficiency enhances aging-related traits in mice. Mechanisms of Ageing and Development. 128: 213-21. PMID 17188333 DOI: 10.1016/j.mad.2006.11.030  0.345
2007 Kostrominova TY, Pasyk KA, Van Remmen H, Richardson AG, Faulkner JA. Adaptive changes in structure of skeletal muscles from adult Sod1 homozygous knockout mice. Cell and Tissue Research. 327: 595-605. PMID 17109119 DOI: 10.1007/S00441-006-0297-Y  0.303
2006 Vasilaki A, Csete M, Pye D, Lee S, Palomero J, McArdle F, Van Remmen H, Richardson A, McArdle A, Faulkner JA, Jackson MJ. Genetic modification of the manganese superoxide dismutase/glutathione peroxidase 1 pathway influences intracellular ROS generation in quiescent, but not contracting, skeletal muscle cells. Free Radical Biology & Medicine. 41: 1719-25. PMID 17145560 DOI: 10.1016/J.Freeradbiomed.2006.09.008  0.419
2006 Chaudhuri AR, de Waal EM, Pierce A, Van Remmen H, Ward WF, Richardson A. Detection of protein carbonyls in aging liver tissue: A fluorescence-based proteomic approach. Mechanisms of Ageing and Development. 127: 849-61. PMID 17002888 DOI: 10.1016/J.Mad.2006.08.006  0.333
2006 Cabelof DC, Ikeno Y, Nyska A, Busuttil RA, Anyangwe N, Vijg J, Matherly LH, Tucker JD, Wilson SH, Richardson A, Heydari AR. Haploinsufficiency in DNA polymerase beta increases cancer risk with age and alters mortality rate. Cancer Research. 66: 7460-5. PMID 16885342 DOI: 10.1158/0008-5472.Can-06-1177  0.317
2006 Mele J, Van Remmen H, Vijg J, Richardson A. Characterization of transgenic mice that overexpress both copper zinc superoxide dismutase and catalase. Antioxidants & Redox Signaling. 8: 628-38. PMID 16677106 DOI: 10.1089/Ars.2006.8.628  0.719
2006 Rader EP, Song W, Van Remmen H, Richardson A, Faulkner JA. Raising the antioxidant levels within mouse muscle fibres does not affect contraction-induced injury. Experimental Physiology. 91: 781-9. PMID 16675501 DOI: 10.1113/Expphysiol.2005.033043  0.407
2006 Ran Q, Gu M, Van Remmen H, Strong R, Roberts JL, Richardson A. Glutathione peroxidase 4 protects cortical neurons from oxidative injury and amyloid toxicity. Journal of Neuroscience Research. 84: 202-8. PMID 16673405 DOI: 10.1002/Jnr.20868  0.367
2006 Pierce A, deWaal E, Van Remmen H, VanRemmen H, Richardson A, Chaudhuri A. A novel approach for screening the proteome for changes in protein conformation. Biochemistry. 45: 3077-85. PMID 16503663 DOI: 10.1021/Bi052031I  0.328
2006 Mansouri A, Muller FL, Liu Y, Ng R, Faulkner J, Hamilton M, Richardson A, Huang TT, Epstein CJ, Van Remmen H. Alterations in mitochondrial function, hydrogen peroxide release and oxidative damage in mouse hind-limb skeletal muscle during aging. Mechanisms of Ageing and Development. 127: 298-306. PMID 16405961 DOI: 10.1016/J.Mad.2005.11.004  0.717
2005 Ikeno Y, Hubbard GB, Lee S, Richardson A, Strong R, Diaz V, Nelson JF. Housing density does not influence the longevity effect of calorie restriction. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 60: 1510-7. PMID 16424282 DOI: 10.1093/Gerona/60.12.1510  0.395
2005 Warner H, Anderson J, Austad S, Bergamini E, Bredesen D, Butler R, Carnes BA, Clark BF, Cristofalo V, Faulkner J, Guarente L, Harrison DE, Kirkwood T, Lithgow G, Martin G, ... ... Richardson A, et al. Science fact and the SENS agenda. What can we reasonably expect from ageing research? Embo Reports. 6: 1006-8. PMID 16264422 DOI: 10.1038/Sj.Embor.7400555  0.308
2005 Ward WF, Qi W, Van Remmen H, Zackert WE, Roberts LJ, Richardson A. Effects of age and caloric restriction on lipid peroxidation: measurement of oxidative stress by F2-isoprostane levels. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 60: 847-51. PMID 16079206 DOI: 10.1093/Gerona/60.7.847  0.357
2005 Stadtman ER, Van Remmen H, Richardson A, Wehr NB, Levine RL. Methionine oxidation and aging. Biochimica Et Biophysica Acta. 1703: 135-40. PMID 15680221 DOI: 10.1016/J.Bbapap.2004.08.010  0.417
2004 Chang J, Van Remmen H, Ward WF, Regnier FE, Richardson A, Cornell J. Processing of data generated by 2-dimensional gel electrophoresis for statistical analysis: missing data, normalization, and statistics. Journal of Proteome Research. 3: 1210-8. PMID 15595730 DOI: 10.1021/Pr049886M  0.559
2004 Bokov A, Chaudhuri A, Richardson A. The role of oxidative damage and stress in aging. Mechanisms of Ageing and Development. 125: 811-26. PMID 15541775 DOI: 10.1016/J.Mad.2004.07.009  0.729
2004 Yang H, Roberts LJ, Shi MJ, Zhou LC, Ballard BR, Richardson A, Guo ZM. Retardation of atherosclerosis by overexpression of catalase or both Cu/Zn-superoxide dismutase and catalase in mice lacking apolipoprotein E. Circulation Research. 95: 1075-81. PMID 15528470 DOI: 10.1161/01.Res.0000149564.49410.0D  0.417
2004 Fu C, Xi L, Wu Y, McCarter R, Richardson A, Hickey M, Han ES. Hepatic genes altered in expression by food restriction are not influenced by the low plasma glucose level in young male GLUT4 transgenic mice. The Journal of Nutrition. 134: 2965-74. PMID 15514260 DOI: 10.1093/Jn/134.11.2965  0.357
2004 Ran Q, Liang H, Gu M, Qi W, Walter CA, Roberts LJ, Herman B, Richardson A, Van Remmen H. Transgenic mice overexpressing glutathione peroxidase 4 are protected against oxidative stress-induced apoptosis. The Journal of Biological Chemistry. 279: 55137-46. PMID 15496407 DOI: 10.1074/Jbc.M410387200  0.694
2004 Richardson A, Liu F, Adamo ML, Van Remmen H, Nelson JF. The role of insulin and insulin-like growth factor-I in mammalian ageing. Best Practice & Research. Clinical Endocrinology & Metabolism. 18: 393-406. PMID 15261845 DOI: 10.1016/J.Beem.2004.02.002  0.31
2004 Van Remmen H, Qi W, Sabia M, Freeman G, Estlack L, Yang H, Mao Guo Z, Huang TT, Strong R, Lee S, Epstein CJ, Richardson A. Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress. Free Radical Biology & Medicine. 36: 1625-34. PMID 15182862 DOI: 10.1016/J.Freeradbiomed.2004.03.016  0.515
2004 Richardson AK, Cox B, McCredie MR, Dite GS, Chang JH, Gertig DM, Southey MC, Giles GG, Hopper JL. Cytomegalovirus, Epstein-Barr virus and risk of breast cancer before age 40 years: a case-control study. British Journal of Cancer. 90: 2149-52. PMID 15150559 DOI: 10.1038/sj.bjc.6601822  0.43
2004 Yang H, Shi M, Story J, Richardson A, Guo Z. Food restriction attenuates age-related increase in the sensitivity of endothelial cells to oxidized lipids. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 59: 316-23. PMID 15071074 DOI: 10.1093/Gerona/59.4.B316  0.393
2004 Chen X, Liang H, Van Remmen H, Vijg J, Richardson A. Catalase transgenic mice: characterization and sensitivity to oxidative stress. Archives of Biochemistry and Biophysics. 422: 197-210. PMID 14759608 DOI: 10.1016/J.Abb.2003.12.023  0.749
2003 Liang H, Masoro EJ, Nelson JF, Strong R, McMahan CA, Richardson A. Genetic mouse models of extended lifespan. Experimental Gerontology. 38: 1353-64. PMID 14698816 DOI: 10.1016/J.Exger.2003.10.019  0.641
2003 Van Remmen H, Ikeno Y, Hamilton M, Pahlavani M, Wolf N, Thorpe SR, Alderson NL, Baynes JW, Epstein CJ, Huang TT, Nelson J, Strong R, Richardson A. Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging. Physiological Genomics. 16: 29-37. PMID 14679299 DOI: 10.1152/Physiolgenomics.00122.2003  0.514
2003 Ran Q, Van Remmen H, Gu M, Qi W, Roberts LJ, Prolla T, Richardson A. Embryonic fibroblasts from Gpx4+/- mice: a novel model for studying the role of membrane peroxidation in biological processes. Free Radical Biology & Medicine. 35: 1101-9. PMID 14572612 DOI: 10.1016/S0891-5849(03)00466-0  0.495
2003 Yang H, Shi M, Richardson A, Vijg J, Guo Z. Attenuation of leukocyte-endothelium interaction by antioxidant enzymes. Free Radical Biology & Medicine. 35: 266-76. PMID 12885588 DOI: 10.1016/S0891-5849(03)00277-6  0.322
2003 Chen X, Mele J, Giese H, Van Remmen H, Dollé ME, Steinhelper M, Richardson A, Vijg J. A strategy for the ubiquitous overexpression of human catalase and CuZn superoxide dismutase genes in transgenic mice. Mechanisms of Ageing and Development. 124: 219-27. PMID 12633942 DOI: 10.1016/S0047-6374(02)00161-6  0.786
2003 Chang J, Van Remmen H, Cornell J, Richardson A, Ward WF. Comparative proteomics: characterization of a two-dimensional gel electrophoresis system to study the effect of aging on mitochondrial proteins. Mechanisms of Ageing and Development. 124: 33-41. PMID 12618004 DOI: 10.1016/S0047-6374(02)00167-7  0.596
2003 Yant LJ, Ran Q, Rao L, Van Remmen H, Shibatani T, Belter JG, Motta L, Richardson A, Prolla TA. The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults. Free Radical Biology & Medicine. 34: 496-502. PMID 12566075 DOI: 10.1016/S0891-5849(02)01360-6  0.473
2003 Yang H, Shi M, VanRemmen H, Chen X, Vijg J, Richardson A, Guo Z. Reduction of pressor response to vasoconstrictor agents by overexpression of catalase in mice. American Journal of Hypertension. 16: 1-5. PMID 12517675 DOI: 10.1016/S0895-7061(02)03086-8  0.58
2002 Dong LQ, Ramos FJ, Wick MJ, Lim MA, Guo Z, Strong R, Richardson A, Liu F. Cloning and characterization of a testis and brain-specific isoform of mouse 3'-phosphoinositide-dependent protein kinase-1, mPDK-1 beta. Biochemical and Biophysical Research Communications. 294: 136-44. PMID 12054753 DOI: 10.1016/S0006-291X(02)00449-7  0.307
2002 Guo Z, Mitchell-Raymundo F, Yang H, Ikeno Y, Nelson J, Diaz V, Richardson A, Reddick R. Dietary restriction reduces atherosclerosis and oxidative stress in the aorta of apolipoprotein E-deficient mice. Mechanisms of Ageing and Development. 123: 1121-31. PMID 12044962 DOI: 10.1016/S0047-6374(02)00008-8  0.45
2001 Guo ZM, Yang H, Hamilton ML, VanRemmen H, Richardson A. Effects of age and food restriction on oxidative DNA damage and antioxidant enzyme activities in the mouse aorta. Mechanisms of Ageing and Development. 122: 1771-86. PMID 11557279 DOI: 10.1016/S0047-6374(01)00298-6  0.435
2001 Hamilton ML, Van Remmen H, Drake JA, Yang H, Guo ZM, Kewitt K, Walter CA, Richardson A. Does oxidative damage to DNA increase with age? Proceedings of the National Academy of Sciences of the United States of America. 98: 10469-74. PMID 11517304 DOI: 10.1073/Pnas.171202698  0.475
2001 Van Remmen H, Williams MD, Guo Z, Estlack L, Yang H, Carlson EJ, Epstein CJ, Huang TT, Richardson A. Knockout mice heterozygous for Sod2 show alterations in cardiac mitochondrial function and apoptosis. American Journal of Physiology. Heart and Circulatory Physiology. 281: H1422-32. PMID 11514315 DOI: 10.1152/Ajpheart.2001.281.3.H1422  0.469
2001 Guo Z, Van Remmen H, Yang H, Chen X, Mele J, Vijg J, Epstein CJ, Ho YS, Richardson A. Changes in expression of antioxidant enzymes affect cell-mediated LDL oxidation and oxidized LDL-induced apoptosis in mouse aortic cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 21: 1131-8. PMID 11451741 DOI: 10.1161/Hq0701.092092  0.783
2001 Remmen HV, Richardson A. Oxidative damage to mitochondria and aging Experimental Gerontology. 36: 957-968. PMID 11404044 DOI: 10.1016/S0531-5565(01)00093-6  0.404
2001 Pahlavani MA, Mele JF, Richardson A. Effect of overexpression of human Cu/Zn-SOD on activation-induced lymphocyte proliferation and apoptosis. Free Radical Biology & Medicine. 30: 1319-27. PMID 11368930 DOI: 10.1016/S0891-5849(01)00529-9  0.67
2001 Hamilton ML, Guo Z, Fuller CD, Van Remmen H, Ward WF, Austad SN, Troyer DA, Thompson I, Richardson A. A reliable assessment of 8-oxo-2-deoxyguanosine levels in nuclear and mitochondrial DNA using the sodium iodide method to isolate DNA. Nucleic Acids Research. 29: 2117-26. PMID 11353081 DOI: 10.1093/Nar/29.10.2117  0.311
2001 Remmen HV, Guo Z, Richardson A. The anti-ageing action of dietary restriction. Novartis Foundation Symposium. 235: 221-233. PMID 11280027 DOI: 10.1002/0470868694.Ch18  0.377
2001 Richardson A, Guo Z. Effects of aging on gene specific repair Advances in Cell Aging and Gerontology. 4: 91-111. DOI: 10.1016/S1566-3124(01)04029-9  0.31
2000 Han ES, Hilsenbeck SG, Richardson A, Nelson JF. cDNA expression arrays reveal incomplete reversal of age-related changes in gene expression by calorie restriction Mechanisms of Ageing and Development. 115: 157-174. PMID 10906510 DOI: 10.1016/S0047-6374(00)00119-6  0.374
2000 Pahlavani MA, Vargas DM, Guo Z, Richardson A. Normal immune function in young and old DNA polymerase-β deficient mice Immunology Letters. 72: 17-21. PMID 10789676 DOI: 10.1016/S0165-2478(00)00159-0  0.385
1999 Van Remmen H, Salvador C, Yang H, Huang TT, Epstein CJ, Richardson A. Characterization of the antioxidant status of the heterozygous manganese superoxide dismutase knockout mouse. Archives of Biochemistry and Biophysics. 363: 91-7. PMID 10049502 DOI: 10.1006/Abbi.1998.1060  0.471
1999 Morgan WW, Richardson A, Sharp ZD, Walter CA. Application of exogenously regulatable promoter systems to transgenic models for the study of aging. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 54: B30-40; discussion B. PMID 10026653 DOI: 10.1093/Gerona/54.1.B30  0.315
1998 Williams MD, Van Remmen H, Conrad CC, Huang TT, Epstein CJ, Richardson A. Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superoxide dismutase knockout mice. The Journal of Biological Chemistry. 273: 28510-5. PMID 9774481 DOI: 10.1074/Jbc.273.43.28510  0.506
1998 Holt PR, Moss SF, Heydari AR, Richardson A. Diet restriction increases apoptosis in the gut of aging rats. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 53: B168-72. PMID 9597039 DOI: 10.1093/Gerona/53A.3.B168  0.308
1998 Remmen Hv, Williams MD, Yang H, Walter CA, Richardson A. Analysis of the transcriptional activity of the 5′‐flanking region of the rat catalase gene in transiently transfected cells and in transgenic mice Journal of Cellular Physiology. 174: 18-26. PMID 9397152 DOI: 10.1002/(Sici)1097-4652(199801)174:1<18::Aid-Jcp3>3.0.Co;2-J  0.323
1997 Richardson A, Heydari AR, Morgan WW, Nelson JF, Sharp ZD, Walter CA. Use of Transgenic Mice in Aging Research. Ilar Journal / National Research Council, Institute of Laboratory Animal Resources. 38: 125-136. PMID 11528054  0.317
1997 Conrad CC, Walter CA, Richardson A, Hanes MA, Grabowski DT. Cadmium toxicity and distribution in metallothionein-I and -II deficient transgenic mice Journal of Toxicology and Environmental Health. 52: 527-543. PMID 9397184 DOI: 10.1080/00984109708984079  0.413
1997 Richardson A, Heydari AR, Morgan WW, Nelson JF, Sharp ZD, Walter CA. Use of transgenic mice in aging research Ilar Journal. 38: 124-136. DOI: 10.1093/Ilar.38.3.124  0.43
1996 Heydari AR, You S, Takahashi R, Gutsmann A, Sarge KD, Richardson A. Effect of caloric restriction on the expression of heat shock protein 70 and the activation of heat shock transcription factor 1. Developmental Genetics. 18: 114-24. PMID 8934873 DOI: 10.1002/(Sici)1520-6408(1996)18:2<114::Aid-Dvg4>3.0.Co;2-C  0.31
1995 Heydari AR, Takahashi R, Gutsmann A, You S, Richardson A. Hsp70 and aging. Experientia. 50: 1092-8. PMID 7988669 DOI: 10.1007/Bf01923466  0.314
1993 Hung L, Richardson A. The effect of aging on the genetic expression of renin by mouse kidney Aging Clinical and Experimental Research. 5: 193-198. PMID 8399464 DOI: 10.1007/Bf03324154  0.327
1991 Semsei I, Rao G, Richardson A. Expression of supreoxide dismutase and catalase in rat brain as a function of age Mechanisms of Ageing and Development. 58: 13-19. PMID 2038211 DOI: 10.1016/0047-6374(91)90116-H  0.332
1990 Heydari AR, Butler JA, Waggoner SM, Richardson A. Age-related changes in protein phosphorylation by rat hepatocytes. Mechanisms of Ageing and Development. 50: 227-48. PMID 2561003 DOI: 10.1016/0047-6374(89)90102-4  0.308
1990 Rao G, Xia E, Nadakavukaren MJ, Richardson A. Effect of Dietary Restriction on the Age-Dependent Changes in the Expression of Antioxidant Enzymes in Rat Liver Journal of Nutrition. 120: 602-609. PMID 2352034 DOI: 10.1093/Jn/120.6.602  0.337
1990 Rao G, Xia E, Richardson A. Effect of age on the expression of antioxidant enzymes in male Fischer F344 rats. Mechanisms of Ageing and Development. 53: 49-60. PMID 2325440 DOI: 10.1016/0047-6374(90)90033-C  0.342
1990 Heller TD, Holt PR, Richardson A. Food restriction retards age-related histological changes in rat small intestine. Gastroenterology. 98: 387-391. PMID 2295393 DOI: 10.1016/0016-5085(90)90829-P  0.313
1990 Cai NS, Li DD, Cheung HT, Richardson A. The expression of granulocyte/macrophage colony-stimulating factor in activated mouse lymphocytes declines with age. Cellular Immunology. 130: 311-9. PMID 2208302 DOI: 10.1016/0008-8749(90)90274-U  0.338
1989 Semsei I, Rao G, Richardson A. Changes in the expression of superoxide dismutase and catalase as a function of age and dietary restriction. Biochemical and Biophysical Research Communications. 164: 620-625. PMID 2818581 DOI: 10.1016/0006-291X(89)91505-2  0.352
1989 Butler JA, Heydari AR, Richardson A. Analysis of effect of age on synthesis of specific proteins by hepatocytes Journal of Cellular Physiology. 141: 400-409. PMID 2808546 DOI: 10.1002/Jcp.1041410222  0.306
1985 Sutter MA, Wood WG, Williamson LS, Strong R, Pickham K, Richardson A. Comparison of the hepatic mixed function oxidase system of young, adult, and old non-human primates (Macaca nemestrina). Biochemical Pharmacology. 34: 2983-7. PMID 4026880 DOI: 10.1016/0006-2952(85)90025-5  0.347
1982 Fitch KL, Nadakavukaren MJ, Richardson A. Age-related changes in the corneal endothelium of the rat. Experimental Gerontology. 17: 179-83. PMID 7140858 DOI: 10.1016/0531-5565(82)90023-7  0.309
1982 Richardson A, Myers JC. A comparison of the cell-free protein synthetic activities of testicular tissue obtained from rats and mice of various ages Comparative Biochemistry and Physiology -- Part B: Biochemistry And. 71: 709-712. PMID 7083821 DOI: 10.1016/0305-0491(82)90485-0  0.399
1982 Richardson A, Cheung HT. Current concepts: I. The relationship between age-related changes in gene expression, protein turnover, and the responsiveness of an organism to stimuli. Life Sciences. 31: 605-13. PMID 6182438 DOI: 10.1016/0024-3205(82)90761-5  0.346
1982 Sutter MA, Chernesky P, Jayaraj A, Richardson A. Metabolic activation of chemical carcinogens by kidney from rats and mice of various ages. Comparative Biochemistry and Physiology. C: Comparative Pharmacology. 73: 435-8. PMID 6129109 DOI: 10.1016/0306-4492(82)90149-6  0.377
1981 Engelmann GL, Richardson A, Katz A, Fierer JA. Age-related changes in isolated rat hepatocytes. Comparison of size, morphology, binucleation, and protein content. Mechanisms of Ageing and Development. 16: 385-95. PMID 7300460 DOI: 10.1016/0047-6374(81)90023-3  0.331
1981 Hardwick J, Hsieh WH, Liu DS, Richardson A. Cell-free protein synthesis by kidney from the aging female Fischer F344 rat. Biochimica Et Biophysica Acta. 652: 204-17. PMID 7213732 DOI: 10.1016/0005-2787(81)90223-9  0.328
1981 Jayaraj A, Richardson A. Metabolic activation of aflatoxin B1 by liver tissue from male Fischer F344 rats of various ages Mechanisms of Ageing and Development. 17: 163-171. PMID 6273666 DOI: 10.1016/0047-6374(81)90082-8  0.32
1980 Ekstrom R, Liu DS, Richardson A. Changes in brain protein synthesis during the life span of male Fischer rats. Gerontology. 26: 121-8. PMID 7358282 DOI: 10.1159/000212405  0.304
1978 Liu DS, Ekstrom R, Spicer JW, Richardson A. Age-related changes in protein, RNA and DNA content and protein synthesis in rat testes. Experimental Gerontology. 13: 197-205. PMID 689115 DOI: 10.1016/0531-5565(78)90013-X  0.318
1976 Layman DK, Ricca GA, Richardson A. The effect of age on protein synthesis and ribosome aggregation to messenger RNA in rat liver Archives of Biochemistry and Biophysics. 173: 246-254. PMID 1259437 DOI: 10.1016/0003-9861(76)90256-3  0.302
1971 Richardson A, McGown E, Henderson L, Swan PB. In vitro amino acid incorporation by the post-mitochondrial supernatant from rat liver Biochimica Et Biophysica Acta (Bba) - Nucleic Acids and Protein Synthesis. 254: 468-477. DOI: 10.1016/0005-2787(71)90881-1  0.312
1969 Richardson AG, Leach FR. Fractionation of competent Bacillus subtilis cells by sucrose density gradient centrifugation. Analytical Biochemistry. 27: 175-8. PMID 4990830 DOI: 10.1016/0003-2697(69)90229-2  0.528
1969 Richardson AG, Pierson DL, Leach FR. The effect of phenethyl alcohol on Bacillus subtilis transformation. II. Transport of DNA and precursors. Biochimica Et Biophysica Acta. 174: 276-81. PMID 4974833 DOI: 10.1016/0005-2787(69)90251-2  0.544
1969 Richardson AG, Leach FR. The effect of phenethyl alcohol on Bacillus subtilis transformation. I. Characterization of the effect. Biochimica Et Biophysica Acta. 174: 264-75. PMID 4974832 DOI: 10.1016/0005-2787(69)90250-0  0.54
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