Ira Tabas - Publications

Cellular Physiology and Biophysics Columbia University, New York, NY 
Medicine and Surgery, Physiology Biology

222 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Wang X, Sommerfeld MR, Jahn-Hofmann K, Cai B, Filliol A, Remotti HE, Schwabe RF, Kannt A, Tabas I. A Therapeutic Silencing RNA Targeting Hepatocyte TAZ Prevents and Reverses Fibrosis in Nonalcoholic Steatohepatitis in Mice. Hepatology Communications. 3: 1221-1234. PMID 31497743 DOI: 10.1002/hep4.1405  0.32
2018 Thomas DG, Doran AC, Fotakis P, Westerterp M, Antonson P, Jiang H, Jiang XC, Gustafsson JÅ, Tabas I, Tall AR. LXR Suppresses Inflammatory Gene Expression and Neutrophil Migration through cis-Repression and Cholesterol Efflux. Cell Reports. 25: 3774-3785.e4. PMID 30590048 DOI: 10.1016/j.celrep.2018.11.100  0.96
2018 Wang W, Liu W, Fidler T, Wang Y, Tang Y, Woods B, Welch C, Cai B, Silvestre-Roig C, Ai D, Yang YG, Hidalgo A, Soehnlein O, Tabas I, Levine RL, et al. Macrophage Inflammation, Erythrophagocytosis, and Accelerated Atherosclerosis in Jak2 Mice. Circulation Research. 123: e35-e47. PMID 30571460 DOI: 10.1161/CIRCRESAHA.118.313283  0.96
2018 Jiao X, Li Z, Wang M, Katiyar S, Di Sante G, Farshchian M, South AP, Cocola C, Colombo D, Reinbold R, Zucchi I, Wu K, Tabas I, Spike BT, Pestell RG. Dachshund Depletion Disrupts Mammary Gland Development and Diverts the Composition of the Mammary Gland Progenitor Pool. Stem Cell Reports. PMID 30554919 DOI: 10.1016/j.stemcr.2018.11.010  0.36
2018 Zhu C, Kim K, Wang X, Bartolome A, Salomao M, Dongiovanni P, Meroni M, Graham MJ, Yates KP, Diehl AM, Schwabe RF, Tabas I, Valenti L, Lavine JE, Pajvani UB. Hepatocyte Notch activation induces liver fibrosis in nonalcoholic steatohepatitis. Science Translational Medicine. 10. PMID 30463916 DOI: 10.1126/scitranslmed.aat0344  0.32
2018 Robinson JG, Williams KJ, Gidding S, Borén J, Tabas I, Fisher EA, Packard C, Pencina M, Fayad ZA, Mani V, Rye KA, Nordestgaard BG, Tybjærg-Hansen A, Douglas PS, Nicholls SJ, et al. Eradicating the Burden of Atherosclerotic Cardiovascular Disease by Lowering Apolipoprotein B Lipoproteins Earlier in Life. Journal of the American Heart Association. 7: e009778. PMID 30371276 DOI: 10.1161/JAHA.118.009778  0.6
2018 Proto JD, Doran AC, Gusarova G, Yurdagul A, Sozen E, Subramanian M, Islam MN, Rymond CC, Du J, Hook J, Kuriakose G, Bhattacharya J, Tabas I. Regulatory T Cells Promote Macrophage Efferocytosis during Inflammation Resolution. Immunity. PMID 30291029 DOI: 10.1016/j.immuni.2018.07.015  0.36
2018 Proto JD, Doran AC, Subramanian M, Wang H, Zhang M, Sozen E, Rymond CC, Kuriakose G, D'Agati V, Winchester R, Sykes M, Yang YG, Tabas I. Hypercholesterolemia induces T cell expansion in humanized immune mice. The Journal of Clinical Investigation. PMID 29708512 DOI: 10.1172/JCI97785  0.36
2017 Doran AC, Ozcan L, Cai B, Zheng Z, Fredman G, Rymond CC, Dorweiler B, Sluimer JC, Hsieh J, Kuriakose G, Tall AR, Tabas I. CAMKIIγ suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosis. The Journal of Clinical Investigation. PMID 28972541 DOI: 10.1172/JCI94735  0.96
2017 Wang Y, Subramanian M, Yurdagul A, Barbosa-Lorenzi VC, Cai B, de Juan-Sanz J, Ryan TA, Nomura M, Maxfield FR, Tabas I. Mitochondrial Fission Promotes the Continued Clearance of Apoptotic Cells by Macrophages. Cell. PMID 28942921 DOI: 10.1016/j.cell.2017.08.041  0.36
2017 Wang Y, Wang W, Wang N, Tall AR, Tabas I. Mitochondrial Oxidative Stress Promotes Atherosclerosis and Neutrophil Extracellular Traps in Aged Mice. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 28596373 DOI: 10.1161/ATVBAHA.117.309580  0.96
2016 Wang X, Zheng Z, Caviglia JM, Corey KE, Herfel TM, Cai B, Masia R, Chung RT, Lefkowitch JH, Schwabe RF, Tabas I. Hepatocyte TAZ/WWTR1 Promotes Inflammation and Fibrosis in Nonalcoholic Steatohepatitis. Cell Metabolism. 24: 848-862. PMID 28068223 DOI: 10.1016/j.cmet.2016.09.016  0.32
2016 Subramanian M, Proto JD, Matsushima GK, Tabas I. Deficiency of AXL in Bone Marrow-Derived Cells Does Not Affect Advanced Atherosclerotic Lesion Progression. Scientific Reports. 6: 39111. PMID 27958361 DOI: 10.1038/srep39111  0.36
2016 Fredman G, Hellmann J, Proto JD, Kuriakose G, Colas RA, Dorweiler B, Connolly ES, Solomon R, Jones DM, Heyer EJ, Spite M, Tabas I. An imbalance between specialized pro-resolving lipid mediators and pro-inflammatory leukotrienes promotes instability of atherosclerotic plaques. Nature Communications. 7: 12859. PMID 27659679 DOI: 10.1038/ncomms12859  0.96
2016 Tabas I. Heart disease: Death-defying plaque cells. Nature. PMID 27437578 DOI: 10.1038/nature18916  0.96
2016 Cai B, Thorp EB, Doran AC, Subramanian M, Sansbury BE, Lin CS, Spite M, Fredman G, Tabas I. MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation. Proceedings of the National Academy of Sciences of the United States of America. PMID 27199481 DOI: 10.1073/pnas.1524292113  0.96
2016 Kamaly N, Fredman G, Fojas JJ, Subramanian M, Choi WI, Zepeda K, Vilos C, Yu M, Gadde S, Wu J, Milton J, Carvalho Leitao R, Rosa Fernandes L, Hasan M, Gao H, ... ... Tabas I, et al. Targeted Interleukin-10 Nanotherapeutics Developed with a Microfluidic Chip Enhance Resolution of Inflammation in Advanced Atherosclerosis. Acs Nano. PMID 27100066 DOI: 10.1021/acsnano.6b01114  0.96
2015 Williams KJ, Tabas I, Fisher EA. How an Artery Heals. Circulation Research. 117: 909-13. PMID 26541678 DOI: 10.1161/CIRCRESAHA.115.307609  0.6
2015 Subramanian M, Ozcan L, Ghorpade DS, Ferrante AW, Tabas I. Suppression of Adaptive Immune Cell Activation Does Not Alter Innate Immune Adipose Inflammation or Insulin Resistance in Obesity. Plos One. 10: e0135842. PMID 26317499 DOI: 10.1371/journal.pone.0135842  0.36
2015 Zhou AX, Wang X, Lin CS, Han J, Yong J, Nadolski MJ, Borén J, Kaufman RJ, Tabas I. C/EBP-Homologous Protein (CHOP) in Vascular Smooth Muscle Cells Regulates Their Proliferation in Aortic Explants and Atherosclerotic Lesions. Circulation Research. 116: 1736-43. PMID 25872946 DOI: 10.1161/CIRCRESAHA.116.305602  0.96
2015 Tabas I, García-Cardeña G, Owens GK. Recent insights into the cellular biology of atherosclerosis. The Journal of Cell Biology. 209: 13-22. PMID 25869663 DOI: 10.1083/jcb.201412052  0.96
2015 Fredman G, Kamaly N, Spolitu S, Milton J, Ghorpade D, Chiasson R, Kuriakose G, Perretti M, Farokhzad O, Farokzhad O, Tabas I. Targeted nanoparticles containing the proresolving peptide Ac2-26 protect against advanced atherosclerosis in hypercholesterolemic mice. Science Translational Medicine. 7: 275ra20. PMID 25695999 DOI: 10.1126/scitranslmed.aaa1065  0.96
2015 Daugherty A, Tabas I, Rader DJ. Accelerating the pace of atherosclerosis research. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 11-2. PMID 25520521 DOI: 10.1161/ATVBAHA.114.304833  0.96
2015 Subramanian M, Thorp E, Tabas I. Identification of a non-growth factor role for GM-CSF in advanced atherosclerosis: promotion of macrophage apoptosis and plaque necrosis through IL-23 signaling. Circulation Research. 116: e13-24. PMID 25348165 DOI: 10.1161/CIRCRESAHA.116.304794  0.96
2014 Fredman G, Ozcan L, Spolitu S, Hellmann J, Spite M, Backs J, Tabas I. Resolvin D1 limits 5-lipoxygenase nuclear localization and leukotriene B4 synthesis by inhibiting a calcium-activated kinase pathway. Proceedings of the National Academy of Sciences of the United States of America. 111: 14530-5. PMID 25246560 DOI: 10.1073/pnas.1410851111  0.96
2014 Ozcan L, Tabas I. CaMKII in cardiometabolic disease. Aging. 6: 430-1. PMID 25011473  0.96
2014 Libby P, Tabas I, Fredman G, Fisher EA. Inflammation and its resolution as determinants of acute coronary syndromes. Circulation Research. 114: 1867-79. PMID 24902971 DOI: 10.1161/CIRCRESAHA.114.302699  0.96
2014 Fredman G, Ozcan L, Tabas I. Common therapeutic targets in cardiometabolic disease. Science Translational Medicine. 6: 239ps5. PMID 24898746 DOI: 10.1126/scitranslmed.3008908  0.96
2014 Wang Y, Tabas I. Emerging roles of mitochondria ROS in atherosclerotic lesions: causation or association? Journal of Atherosclerosis and Thrombosis. 21: 381-90. PMID 24717761 DOI: DN/JST.JSTAGE/jat/23929  0.96
2014 Wang M, Subramanian M, Abramowicz S, Murphy AJ, Gonen A, Witztum J, Welch C, Tabas I, Westerterp M, Tall AR. Interleukin-3/granulocyte macrophage colony-stimulating factor receptor promotes stem cell expansion, monocytosis, and atheroma macrophage burden in mice with hematopoietic ApoE deficiency. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 976-84. PMID 24651678 DOI: 10.1161/ATVBAHA.113.303097  0.96
2014 Subramanian M, Tabas I. A new RIDDle in DC-mediated cross-presentation. Nature Immunology. 15: 213-5. PMID 24549063 DOI: 10.1038/ni.2826  0.96
2014 Subramanian M, Hayes CD, Thome JJ, Thorp E, Matsushima GK, Herz J, Farber DL, Liu K, Lakshmana M, Tabas I. An AXL/LRP-1/RANBP9 complex mediates DC efferocytosis and antigen cross-presentation in vivo. The Journal of Clinical Investigation. 124: 1296-308. PMID 24509082 DOI: 10.1172/JCI72051  0.96
2014 Wang Y, Wang GZ, Rabinovitch PS, Tabas I. Macrophage mitochondrial oxidative stress promotes atherosclerosis and nuclear factor-κB-mediated inflammation in macrophages. Circulation Research. 114: 421-33. PMID 24297735 DOI: 10.1161/CIRCRESAHA.114.302153  0.96
2014 Subramanian M, Tabas I. Dendritic cells in atherosclerosis. Seminars in Immunopathology. 36: 93-102. PMID 24196454 DOI: 10.1007/s00281-013-0400-x  0.96
2014 Fredman G, Tabas I. Macrophages govern the progression and termination of inflammation in atherosclerosis and metabolic diseases Macrophages: Biology and Role in the Pathology of Diseases. 387-403. DOI: 10.1007/978-1-4939-1311-4_18  0.96
2013 Ozcan L, Cristina de Souza J, Harari AA, Backs J, Olson EN, Tabas I. Activation of calcium/calmodulin-dependent protein kinase II in obesity mediates suppression of hepatic insulin signaling. Cell Metabolism. 18: 803-15. PMID 24268736 DOI: 10.1016/j.cmet.2013.10.011  0.96
2013 Tabas I. Making things stick in the fight against atherosclerosis. Circulation Research. 112: 1094-6. PMID 23580771 DOI: 10.1161/CIRCRESAHA.113.301227  0.96
2013 Zhou AX, Tabas I. The UPR in atherosclerosis. Seminars in Immunopathology. 35: 321-32. PMID 23553213 DOI: 10.1007/s00281-013-0372-x  0.96
2013 Kamaly N, Fredman G, Subramanian M, Gadde S, Pesic A, Cheung L, Fayad ZA, Langer R, Tabas I, Farokhzad OC. Development and in vivo efficacy of targeted polymeric inflammation-resolving nanoparticles. Proceedings of the National Academy of Sciences of the United States of America. 110: 6506-11. PMID 23533277 DOI: 10.1073/pnas.1303377110  0.96
2013 Tabas I, Glass CK. Anti-inflammatory therapy in chronic disease: challenges and opportunities. Science (New York, N.Y.). 339: 166-72. PMID 23307734 DOI: 10.1126/science.1230720  0.96
2013 Subramanian M, Thorp E, Hansson GK, Tabas I. Treg-mediated suppression of atherosclerosis requires MYD88 signaling in DCs. The Journal of Clinical Investigation. 123: 179-88. PMID 23257360 DOI: 10.1172/JCI64617  0.96
2013 Rong JX, Blachford C, Feig JE, Bander I, Mayne J, Kusunoki J, Miller C, Davis M, Wilson M, Dehn S, Thorp E, Tabas I, Taubman MB, Rudel LL, Fisher EA. ACAT inhibition reduces the progression of preexisting, advanced atherosclerotic mouse lesions without plaque or systemic toxicity. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 4-12. PMID 23139293 DOI: 10.1161/ATVBAHA.112.252056  0.96
2013 Richards MR, Black AS, Bonnet DJ, Barish GD, Woo CW, Tabas I, Curtiss LK, Tobias PS. The LPS2 mutation in TRIF is atheroprotective in hyperlipidemic low density lipoprotein receptor knockout mice. Innate Immunity. 19: 20-9. PMID 22637968 DOI: 10.1177/1753425912447130  0.96
2012 Tabas I. Cardiology: Bad matters made worse. Nature. 487: 306-8. PMID 22810692 DOI: 10.1038/487306a  0.96
2012 Liang CP, Han S, Li G, Tabas I, Tall AR. Impaired MEK signaling and SERCA expression promote ER stress and apoptosis in insulin-resistant macrophages and are reversed by exenatide treatment. Diabetes. 61: 2609-20. PMID 22751695 DOI: 10.2337/db11-1415  0.96
2012 Ozcan L, Wong CC, Li G, Xu T, Pajvani U, Park SK, Wronska A, Chen BX, Marks AR, Fukamizu A, Backs J, Singer HA, Yates JR, Accili D, Tabas I. Calcium signaling through CaMKII regulates hepatic glucose production in fasting and obesity. Cell Metabolism. 15: 739-51. PMID 22503562 DOI: 10.1016/j.cmet.2012.03.002  0.36
2012 Wang Y, Li G, Goode J, Paz JC, Ouyang K, Screaton R, Fischer WH, Chen J, Tabas I, Montminy M. Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes. Nature. 485: 128-32. PMID 22495310 DOI: 10.1038/nature10988  0.96
2012 Ai D, Baez JM, Jiang H, Conlon DM, Hernandez-Ono A, Frank-Kamenetsky M, Milstein S, Fitzgerald K, Murphy AJ, Woo CW, Strong A, Ginsberg HN, Tabas I, Rader DJ, Tall AR. Activation of ER stress and mTORC1 suppresses hepatic sortilin-1 levels in obese mice. The Journal of Clinical Investigation. 122: 1677-87. PMID 22466652 DOI: 10.1172/JCI61248  0.96
2012 Liao X, Sluimer JC, Wang Y, Subramanian M, Brown K, Pattison JS, Robbins J, Martinez J, Tabas I. Macrophage autophagy plays a protective role in advanced atherosclerosis. Cell Metabolism. 15: 545-53. PMID 22445600 DOI: 10.1016/j.cmet.2012.01.022  0.96
2012 Tsuchiya K, Tanaka J, Shuiqing Y, Welch CL, DePinho RA, Tabas I, Tall AR, Goldberg IJ, Accili D. FoxOs integrate pleiotropic actions of insulin in vascular endothelium to protect mice from atherosclerosis. Cell Metabolism. 15: 372-81. PMID 22405072 DOI: 10.1016/j.cmet.2012.01.018  0.96
2012 Ozcan L, Tabas I. Role of endoplasmic reticulum stress in metabolic disease and other disorders. Annual Review of Medicine. 63: 317-28. PMID 22248326 DOI: 10.1146/annurev-med-043010-144749  0.96
2012 Woo CW, Kutzler L, Kimball SR, Tabas I. Toll-like receptor activation suppresses ER stress factor CHOP and translation inhibition through activation of eIF2B. Nature Cell Biology. 14: 192-200. PMID 22231169 DOI: 10.1038/ncb2408  0.96
2011 Scull CM, Tabas I. Mechanisms of ER stress-induced apoptosis in atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 2792-7. PMID 22096099 DOI: 10.1161/ATVBAHA.111.224881  0.96
2011 Bornfeldt KE, Tabas I. Insulin resistance, hyperglycemia, and atherosclerosis. Cell Metabolism. 14: 575-85. PMID 22055501 DOI: 10.1016/j.cmet.2011.07.015  0.96
2011 Thorp E, Subramanian M, Tabas I. The role of macrophages and dendritic cells in the clearance of apoptotic cells in advanced atherosclerosis. European Journal of Immunology. 41: 2515-8. PMID 21952808 DOI: 10.1002/eji.201141719  0.96
2011 Tsuchiya K, Banks AS, Liang CP, Tabas I, Tall AR, Accili D. Homozygosity for an allele encoding deacetylated FoxO1 protects macrophages from cholesterol-induced inflammation without increasing apoptosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 2920-8. PMID 21940942 DOI: 10.1161/ATVBAHA.110.219477  0.96
2011 Thorp E, Vaisar T, Subramanian M, Mautner L, Blobel C, Tabas I. Shedding of the Mer tyrosine kinase receptor is mediated by ADAM17 protein through a pathway involving reactive oxygen species, protein kinase Cδ, and p38 mitogen-activated protein kinase (MAPK). The Journal of Biological Chemistry. 286: 33335-44. PMID 21828049 DOI: 10.1074/jbc.M111.263020  0.96
2011 Tabas I. Pulling down the plug on atherosclerosis: finding the culprit in your heart. Nature Medicine. 17: 791-3. PMID 21738159 DOI: 10.1038/nm0711-791  0.96
2011 Ouimet M, Franklin V, Mak E, Liao X, Tabas I, Marcel YL. Autophagy regulates cholesterol efflux from macrophage foam cells via lysosomal acid lipase. Cell Metabolism. 13: 655-67. PMID 21641547 DOI: 10.1016/j.cmet.2011.03.023  0.96
2011 Moore KJ, Tabas I. Macrophages in the pathogenesis of atherosclerosis. Cell. 145: 341-55. PMID 21529710 DOI: 10.1016/j.cell.2011.04.005  0.96
2011 Tabas I, Ron D. Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress. Nature Cell Biology. 13: 184-90. PMID 21364565 DOI: 10.1038/ncb0311-184  0.96
2011 Thorp E, Iwawaki T, Miura M, Tabas I. A reporter for tracking the UPR in vivo reveals patterns of temporal and cellular stress during atherosclerotic progression. Journal of Lipid Research. 52: 1033-8. PMID 21357531 DOI: 10.1194/jlr.D012492  0.96
2011 Shechtman CF, Henneberry AL, Seimon TA, Tinkelenberg AH, Wilcox LJ, Lee E, Fazlollahi M, Munkacsi AB, Bussemaker HJ, Tabas I, Sturley SL. Loss of subcellular lipid transport due to ARV1 deficiency disrupts organelle homeostasis and activates the unfolded protein response. The Journal of Biological Chemistry. 286: 11951-9. PMID 21266578 DOI: 10.1074/jbc.M110.215038  0.96
2010 Li G, Scull C, Ozcan L, Tabas I. NADPH oxidase links endoplasmic reticulum stress, oxidative stress, and PKR activation to induce apoptosis. The Journal of Cell Biology. 191: 1113-25. PMID 21135141 DOI: 10.1083/jcb.201006121  0.96
2010 Seimon TA, Nadolski MJ, Liao X, Magallon J, Nguyen M, Feric NT, Koschinsky ML, Harkewicz R, Witztum JL, Tsimikas S, Golenbock D, Moore KJ, Tabas I. Atherogenic lipids and lipoproteins trigger CD36-TLR2-dependent apoptosis in macrophages undergoing endoplasmic reticulum stress. Cell Metabolism. 12: 467-82. PMID 21035758 DOI: 10.1016/j.cmet.2010.09.010  0.96
2010 Tabas I. The role of endoplasmic reticulum stress in the progression of atherosclerosis. Circulation Research. 107: 839-50. PMID 20884885 DOI: 10.1161/CIRCRESAHA.110.224766  0.96
2010 Seimon TA, Kim MJ, Blumenthal A, Koo J, Ehrt S, Wainwright H, Bekker LG, Kaplan G, Nathan C, Tabas I, Russell DG. Induction of ER stress in macrophages of tuberculosis granulomas. Plos One. 5: e12772. PMID 20856677 DOI: 10.1371/journal.pone.0012772  0.96
2010 Tam C, Idone V, Devlin C, Fernandes MC, Flannery A, He X, Schuchman E, Tabas I, Andrews NW. Exocytosis of acid sphingomyelinase by wounded cells promotes endocytosis and plasma membrane repair. The Journal of Cell Biology. 189: 1027-38. PMID 20530211 DOI: 10.1083/jcb.201003053  0.96
2010 Yvan-Charvet L, Pagler TA, Seimon TA, Thorp E, Welch CL, Witztum JL, Tabas I, Tall AR. ABCA1 and ABCG1 protect against oxidative stress-induced macrophage apoptosis during efferocytosis. Circulation Research. 106: 1861-9. PMID 20431058 DOI: 10.1161/CIRCRESAHA.110.217281  0.96
2010 Devlin C, Pipalia NH, Liao X, Schuchman EH, Maxfield FR, Tabas I. Improvement in lipid and protein trafficking in Niemann-Pick C1 cells by correction of a secondary enzyme defect. Traffic (Copenhagen, Denmark). 11: 601-15. PMID 20412078 DOI: 10.1111/j.1600-0854.2010.01046.x  0.96
2010 Nawrocki AR, Hofmann SM, Teupser D, Basford JE, Durand JL, Jelicks LA, Woo CW, Kuriakose G, Factor SM, Tanowitz HB, Hui DY, Tabas I, Scherer PE. Lack of association between adiponectin levels and atherosclerosis in mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 1159-65. PMID 20299691 DOI: 10.1161/ATVBAHA.109.195826  0.96
2010 Tabas I, Tall A, Accili D. The impact of macrophage insulin resistance on advanced atherosclerotic plaque progression. Circulation Research. 106: 58-67. PMID 20056946 DOI: 10.1161/CIRCRESAHA.109.208488  0.96
2010 Yeboah J, McNamara C, Jiang XC, Tabas I, Herrington DM, Burke GL, Shea S. Association of plasma sphingomyelin levels and incident coronary heart disease events in an adult population: Multi-Ethnic Study of Atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 628-33. PMID 20032291 DOI: 10.1161/ATVBAHA.109.199281  0.96
2010 Ozcan L, Tabas I. Pivotal role of calcium/calmodulin-dependent protein kinase II in ER stress-induced apoptosis. Cell Cycle (Georgetown, Tex.). 9: 223-4. PMID 20023415 DOI: 10.4161/cc.9.2.10596  0.96
2010 Tabas I. Macrophage death and defective inflammation resolution in atherosclerosis. Nature Reviews. Immunology. 10: 36-46. PMID 19960040 DOI: 10.1038/nri2675  0.96
2009 Woo CW, Cui D, Arellano J, Dorweiler B, Harding H, Fitzgerald KA, Ron D, Tabas I. Adaptive suppression of the ATF4-CHOP branch of the unfolded protein response by toll-like receptor signalling. Nature Cell Biology. 11: 1473-80. PMID 19855386 DOI: 10.1038/ncb1996  0.96
2009 Li S, Sun Y, Liang CP, Thorp EB, Han S, Jehle AW, Saraswathi V, Pridgen B, Kanter JE, Li R, Welch CL, Hasty AH, Bornfeldt KE, Breslow JL, Tabas I, et al. Defective phagocytosis of apoptotic cells by macrophages in atherosclerotic lesions of ob/ob mice and reversal by a fish oil diet. Circulation Research. 105: 1072-82. PMID 19834009 DOI: 10.1161/CIRCRESAHA.109.199570  0.96
2009 Li G, Mongillo M, Chin KT, Harding H, Ron D, Marks AR, Tabas I. Role of ERO1-alpha-mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress-induced apoptosis. The Journal of Cell Biology. 186: 783-92. PMID 19752026 DOI: 10.1083/jcb.200904060  0.96
2009 Tabas I, Seimon T, Timmins J, Li G, Lim W. Macrophage apoptosis in advanced atherosclerosis. Annals of the New York Academy of Sciences. 1173: E40-5. PMID 19751413 DOI: 10.1111/j.1749-6632.2009.04957.x  0.96
2009 Timmins JM, Ozcan L, Seimon TA, Li G, Malagelada C, Backs J, Backs T, Bassel-Duby R, Olson EN, Anderson ME, Tabas I. Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways. The Journal of Clinical Investigation. 119: 2925-41. PMID 19741297 DOI: 10.1172/JCI38857  0.96
2009 Thorp E, Tabas I. Differential effects of pioglitazone on advanced atherosclerotic lesions. The American Journal of Pathology. 175: 1348. PMID 19661438 DOI: 10.2353/ajpath.2009.090483  0.96
2009 Thorp E, Li G, Seimon TA, Kuriakose G, Ron D, Tabas I. Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe-/- and Ldlr-/- mice lacking CHOP. Cell Metabolism. 9: 474-81. PMID 19416717 DOI: 10.1016/j.cmet.2009.03.003  0.96
2009 Thorp E, Tabas I. Mechanisms and consequences of efferocytosis in advanced atherosclerosis. Journal of Leukocyte Biology. 86: 1089-95. PMID 19414539 DOI: 10.1189/jlb.0209115  0.96
2009 Seimon TA, Wang Y, Han S, Senokuchi T, Schrijvers DM, Kuriakose G, Tall AR, Tabas IA. Macrophage deficiency of p38alpha MAPK promotes apoptosis and plaque necrosis in advanced atherosclerotic lesions in mice. The Journal of Clinical Investigation. 119: 886-98. PMID 19287091 DOI: 10.1172/JCI37262  0.96
2009 Tabas I. Macrophage apoptosis in atherosclerosis: consequences on plaque progression and the role of endoplasmic reticulum stress. Antioxidants & Redox Signaling. 11: 2333-9. PMID 19243235 DOI: 10.1089/ars.2009.2469  0.96
2009 Sun Y, Ishibashi M, Seimon T, Lee M, Sharma SM, Fitzgerald KA, Samokhin AO, Wang Y, Sayers S, Aikawa M, Jerome WG, Ostrowski MC, Bromme D, Libby P, Tabas IA, et al. Free cholesterol accumulation in macrophage membranes activates Toll-like receptors and p38 mitogen-activated protein kinase and induces cathepsin K. Circulation Research. 104: 455-65. PMID 19122179 DOI: 10.1161/CIRCRESAHA.108.182568  0.96
2009 Thorp E, Li Y, Bao L, Yao PM, Kuriakose G, Rong J, Fisher EA, Tabas I. Brief report: increased apoptosis in advanced atherosclerotic lesions of Apoe-/- mice lacking macrophage Bcl-2. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 169-72. PMID 18988889 DOI: 10.1161/ATVBAHA.108.176495  0.96
2009 Seimon T, Tabas I. Mechanisms and consequences of macrophage apoptosis in atherosclerosis. Journal of Lipid Research. 50: S382-7. PMID 18953058 DOI: 10.1194/jlr.R800032-JLR200  0.96
2009 Manning-Tobin JJ, Moore KJ, Seimon TA, Bell SA, Sharuk M, Alvarez-Leite JI, de Winther MP, Tabas I, Freeman MW. Loss of SR-A and CD36 activity reduces atherosclerotic lesion complexity without abrogating foam cell formation in hyperlipidemic mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 19-26. PMID 18948635 DOI: 10.1161/ATVBAHA.108.176644  0.96
2008 Li Y, Zhang Y, Dorweiler B, Cui D, Wang T, Woo CW, Brunkan CS, Wolberger C, Imai S, Tabas I. Extracellular Nampt promotes macrophage survival via a nonenzymatic interleukin-6/STAT3 signaling mechanism. The Journal of Biological Chemistry. 283: 34833-43. PMID 18945671 DOI: 10.1074/jbc.M805866200  0.96
2008 Packard RR, Maganto-García E, Gotsman I, Tabas I, Libby P, Lichtman AH. CD11c(+) dendritic cells maintain antigen processing, presentation capabilities, and CD4(+) T-cell priming efficacy under hypercholesterolemic conditions associated with atherosclerosis. Circulation Research. 103: 965-73. PMID 18832748 DOI: 10.1161/CIRCRESAHA.108.185793  0.96
2008 Senokuchi T, Liang CP, Seimon TA, Han S, Matsumoto M, Banks AS, Paik JH, DePinho RA, Accili D, Tabas I, Tall AR. Forkhead transcription factors (FoxOs) promote apoptosis of insulin-resistant macrophages during cholesterol-induced endoplasmic reticulum stress. Diabetes. 57: 2967-76. PMID 18728232 DOI: 10.2337/db08-0520  0.96
2008 Devlin CM, Leventhal AR, Kuriakose G, Schuchman EH, Williams KJ, Tabas I. Acid sphingomyelinase promotes lipoprotein retention within early atheromata and accelerates lesion progression. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 1723-30. PMID 18669882 DOI: 10.1161/ATVBAHA.108.173344  0.96
2008 Iqbal J, Dai K, Seimon T, Jungreis R, Oyadomari M, Kuriakose G, Ron D, Tabas I, Hussain MM. IRE1beta inhibits chylomicron production by selectively degrading MTP mRNA. Cell Metabolism. 7: 445-55. PMID 18460335 DOI: 10.1016/j.cmet.2008.03.005  0.96
2008 Thorp E, Cui D, Schrijvers DM, Kuriakose G, Tabas I. Mertk receptor mutation reduces efferocytosis efficiency and promotes apoptotic cell accumulation and plaque necrosis in atherosclerotic lesions of apoe-/- mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 1421-8. PMID 18451332 DOI: 10.1161/ATVBAHA.108.167197  0.96
2008 Lim WS, Timmins JM, Seimon TA, Sadler A, Kolodgie FD, Virmani R, Tabas I. Signal transducer and activator of transcription-1 is critical for apoptosis in macrophages subjected to endoplasmic reticulum stress in vitro and in advanced atherosclerotic lesions in vivo. Circulation. 117: 940-51. PMID 18227389 DOI: 10.1161/CIRCULATIONAHA.107.711275  0.96
2008 Tabas I. Lipids and atherosclerosis Biochemistry of Lipids, Lipoproteins and Membranes. 579-605. DOI: 10.1016/B978-044453219-0.50023-4  0.96
2007 Tabas I, Seimon T, Arellano J, Li Y, Forcheron F, Cui D, Han S, Liang CP, Tall A, Accili D. The impact of insulin resistance on macrophage death pathways in advanced atherosclerosis. Novartis Foundation Symposium. 286: 99-109; discussion 1. PMID 18269177  0.96
2007 Tabas I. Apoptosis and efferocytosis in mouse models of atherosclerosis. Current Drug Targets. 8: 1288-96. PMID 18220705 DOI: 10.2174/138945007783220623  0.96
2007 Thorp E, Kuriakose G, Shah YM, Gonzalez FJ, Tabas I. Pioglitazone increases macrophage apoptosis and plaque necrosis in advanced atherosclerotic lesions of nondiabetic low-density lipoprotein receptor-null mice. Circulation. 116: 2182-90. PMID 17967777 DOI: 10.1161/CIRCULATIONAHA.107.698852  0.96
2007 Tabas I, Williams KJ, Borén J. Subendothelial lipoprotein retention as the initiating process in atherosclerosis: update and therapeutic implications. Circulation. 116: 1832-44. PMID 17938300 DOI: 10.1161/CIRCULATIONAHA.106.676890  0.96
2007 Bao S, Li Y, Lei X, Wohltmann M, Jin W, Bohrer A, Semenkovich CF, Ramanadham S, Tabas I, Turk J. Attenuated free cholesterol loading-induced apoptosis but preserved phospholipid composition of peritoneal macrophages from mice that do not express group VIA phospholipase A2. The Journal of Biological Chemistry. 282: 27100-14. PMID 17627946 DOI: 10.1074/jbc.M701316200  0.96
2007 Cui D, Thorp E, Li Y, Wang N, Yvan-Charvet L, Tall AR, Tabas I. Pivotal advance: macrophages become resistant to cholesterol-induced death after phagocytosis of apoptotic cells. Journal of Leukocyte Biology. 82: 1040-50. PMID 17576822 DOI: 10.1189/jlb.0307192  0.96
2007 Tabas I. A two-carbon switch to sterol-induced autophagic death. Autophagy. 3: 38-41. PMID 17172803  0.96
2007 Li Y, Tabas I. The inflammatory cytokine response of cholesterol-enriched macrophages is dampened by stimulated pinocytosis. Journal of Leukocyte Biology. 81: 483-91. PMID 17062603 DOI: 10.1189/jlb.0806518  0.96
2007 Tabas I, Black PN, Spiegelman BM, O'Rahilly S, Bernlohr DA, Glass CK, Muoio DM, Attie AD. Final discussion: Nutrition, ageing and lipotoxicity Novartis Foundation Symposium. 286: 200-203.  0.96
2006 Seimon TA, Obstfeld A, Moore KJ, Golenbock DT, Tabas I. Combinatorial pattern recognition receptor signaling alters the balance of life and death in macrophages. Proceedings of the National Academy of Sciences of the United States of America. 103: 19794-9. PMID 17167049 DOI: 10.1073/pnas.0609671104  0.96
2006 Bao L, Li Y, Deng SX, Landry D, Tabas I. Sitosterol-containing lipoproteins trigger free sterol-induced caspase-independent death in ACAT-competent macrophages. The Journal of Biological Chemistry. 281: 33635-49. PMID 16935859 DOI: 10.1074/jbc.M606339200  0.96
2006 Williams KJ, Tabas I. Letter by Williams and Tabas regarding article "atherosclerosis 2005: recent discoveries and novel hypotheses". Circulation. 113: e782; author reply e. PMID 16735683 DOI: 10.1161/CIRCULATIONAHA.105.606962  0.96
2006 Nelson JC, Jiang XC, Tabas I, Tall A, Shea S. Plasma sphingomyelin and subclinical atherosclerosis: findings from the multi-ethnic study of atherosclerosis. American Journal of Epidemiology. 163: 903-12. PMID 16611667 DOI: 10.1093/aje/kwj140  0.96
2006 Han S, Liang CP, DeVries-Seimon T, Ranalletta M, Welch CL, Collins-Fletcher K, Accili D, Tabas I, Tall AR. Macrophage insulin receptor deficiency increases ER stress-induced apoptosis and necrotic core formation in advanced atherosclerotic lesions. Cell Metabolism. 3: 257-66. PMID 16581003 DOI: 10.1016/j.cmet.2006.02.008  0.96
2006 Gerbod-Giannone MC, Li Y, Holleboom A, Han S, Hsu LC, Tabas I, Tall AR. TNFalpha induces ABCA1 through NF-kappaB in macrophages and in phagocytes ingesting apoptotic cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 3112-7. PMID 16492740 DOI: 10.1073/pnas.0510345103  0.96
2006 Boullier A, Li Y, Quehenberger O, Palinski W, Tabas I, Witztum JL, Miller YI. Minimally oxidized LDL offsets the apoptotic effects of extensively oxidized LDL and free cholesterol in macrophages. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 1169-76. PMID 16484596 DOI: 10.1161/01.ATV.0000210279.97308.9a  0.96
2006 Li Y, Gerbod-Giannone MC, Seitz H, Cui D, Thorp E, Tall AR, Matsushima GK, Tabas I. Cholesterol-induced apoptotic macrophages elicit an inflammatory response in phagocytes, which is partially attenuated by the Mer receptor. The Journal of Biological Chemistry. 281: 6707-17. PMID 16380374 DOI: 10.1074/jbc.M510579200  0.96
2005 Maxfield FR, Tabas I. Role of cholesterol and lipid organization in disease. Nature. 438: 612-21. PMID 16319881 DOI: 10.1038/nature04399  0.96
2005 Devries-Seimon T, Li Y, Yao PM, Stone E, Wang Y, Davis RJ, Flavell R, Tabas I. Cholesterol-induced macrophage apoptosis requires ER stress pathways and engagement of the type A scavenger receptor. The Journal of Cell Biology. 171: 61-73. PMID 16203857 DOI: 10.1083/jcb.200502078  0.96
2005 Tabas I. Consequences and therapeutic implications of macrophage apoptosis in atherosclerosis: the importance of lesion stage and phagocytic efficiency. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 2255-64. PMID 16141399 DOI: 10.1161/01.ATV.0000184783.04864.9f  0.96
2005 Williams KJ, Tabas I. Lipoprotein retention--and clues for atheroma regression. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 1536-40. PMID 16055756 DOI: 10.1161/01.ATV.0000174795.62387.d3  0.96
2005 Jacobs RL, Stead LM, Devlin C, Tabas I, Brosnan ME, Brosnan JT, Vance DE. Physiological regulation of phospholipid methylation alters plasma homocysteine in mice. The Journal of Biological Chemistry. 280: 28299-305. PMID 15958390 DOI: 10.1074/jbc.M501971200  0.96
2005 Li Y, Schwabe RF, DeVries-Seimon T, Yao PM, Gerbod-Giannone MC, Tall AR, Davis RJ, Flavell R, Brenner DA, Tabas I. Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-alpha and interleukin-6: model of NF-kappaB- and map kinase-dependent inflammation in advanced atherosclerosis. The Journal of Biological Chemistry. 280: 21763-72. PMID 15826936 DOI: 10.1074/jbc.M501759200  0.96
2005 Wüstner D, Mondal M, Tabas I, Maxfield FR. Direct observation of rapid internalization and intracellular transport of sterol by macrophage foam cells. Traffic (Copenhagen, Denmark). 6: 396-412. PMID 15813750 DOI: 10.1111/j.1600-0854.2005.00285.x  0.96
2005 Mintzer RJ, Appell KC, Cole A, Johns A, Pagila R, Polokoff MA, Tabas I, Snider RM, Meurer-Ogden JA. A novel high-throughput screening format to identify inhibitors of secreted acid sphingomyelinase. Journal of Biomolecular Screening. 10: 225-34. PMID 15809318 DOI: 10.1177/1087057104272546  0.96
2005 Wang L, Magdaleno S, Tabas I, Jackowski S. Early embryonic lethality in mice with targeted deletion of the CTP:phosphocholine cytidylyltransferase alpha gene (Pcyt1a). Molecular and Cellular Biology. 25: 3357-63. PMID 15798219 DOI: 10.1128/MCB.25.8.3357-3363.2005  0.96
2005 Baez JM, Tabas I, Cohen DE. Decreased lipid efflux and increased susceptibility to cholesterol-induced apoptosis in macrophages lacking phosphatidylcholine transfer protein. The Biochemical Journal. 388: 57-63. PMID 15628972 DOI: 10.1042/BJ20041899  0.96
2004 Tabas I. Sphingolipids and atherosclerosis: a mechanistic connection? A therapeutic opportunity? Circulation. 110: 3400-1. PMID 15569847 DOI: 10.1161/01.CIR.0000150861.98087.56  0.96
2004 Jacobs RL, Devlin C, Tabas I, Vance DE. Targeted deletion of hepatic CTP:phosphocholine cytidylyltransferase alpha in mice decreases plasma high density and very low density lipoproteins. The Journal of Biological Chemistry. 279: 47402-10. PMID 15331603 DOI: 10.1074/jbc.M404027200  0.96
2004 Li Y, Ge M, Ciani L, Kuriakose G, Westover EJ, Dura M, Covey DF, Freed JH, Maxfield FR, Lytton J, Tabas I. Enrichment of endoplasmic reticulum with cholesterol inhibits sarcoplasmic-endoplasmic reticulum calcium ATPase-2b activity in parallel with increased order of membrane lipids: implications for depletion of endoplasmic reticulum calcium stores and apoptosis in cholesterol-loaded macrophages. The Journal of Biological Chemistry. 279: 37030-9. PMID 15215242 DOI: 10.1074/jbc.M405195200  0.96
2004 Tabas I. Apoptosis and plaque destabilization in atherosclerosis: The role of macrophage apoptosis induced by cholesterol Cell Death and Differentiation. 11. PMID 15143347 DOI: 10.1038/sj.cdd.4401444  0.96
2004 Liang CP, Han S, Okamoto H, Carnemolla R, Tabas I, Accili D, Tall AR. Increased CD36 protein as a response to defective insulin signaling in macrophages. The Journal of Clinical Investigation. 113: 764-73. PMID 14991075 DOI: 10.1172/JCI19528  0.96
2004 Leventhal AR, Leslie CC, Tabas I. Suppression of macrophage eicosanoid synthesis by atherogenic lipoproteins is profoundly affected by cholesterol-fatty acyl esterification and the Niemann-Pick C pathway of lipid trafficking. The Journal of Biological Chemistry. 279: 8084-92. PMID 14638686 DOI: 10.1074/jbc.M310672200  0.96
2003 Patel M, Morrow J, Maxfield FR, Strickland DK, Greenberg S, Tabas I. The cytoplasmic domain of the low density lipoprotein (LDL) receptor-related protein, but not that of the LDL receptor, triggers phagocytosis. The Journal of Biological Chemistry. 278: 44799-807. PMID 12941948 DOI: 10.1074/jbc.M308982200  0.96
2003 Feng B, Zhang D, Kuriakose G, Devlin CM, Kockx M, Tabas I. Niemann-Pick C heterozygosity confers resistance to lesional necrosis and macrophage apoptosis in murine atherosclerosis. Proceedings of the National Academy of Sciences of the United States of America. 100: 10423-8. PMID 12923293 DOI: 10.1073/pnas.1732494100  0.96
2002 Tabas I. Consequences of cellular cholesterol accumulation: Basic concepts and physiological implications Journal of Clinical Investigation. 110: 905-911. PMID 12370266 DOI: 10.1172/JCI200216452  0.96
2002 Feng B, Tabas I. ABCA1-mediated cholesterol efflux is defective in free cholesterol-loaded macrophages: Mechanism involves enhanced ABCA1 degradation in a process requiring full NPC1 activity Journal of Biological Chemistry. 277: 43271-43280. PMID 12215451 DOI: 10.1074/jbc.M207532200  0.96
2002 Tabas I. Cholesterol in health and disease Journal of Clinical Investigation. 110: 583-590. PMID 12208856 DOI: 10.1172/JCI200216381  0.96
2002 Williams KJ, Tabas I. Atherosclerosis and inflammation [4] Science. 297: 521-522. PMID 12143880 DOI: 10.1126/science.297.5581.521  0.96
2002 Devlin CM, Kuriakose G, Hirsch E, Tabas I. Genetic alterations of IL-1 receptor antagonist in mice affect plasma cholesterol level and foam cell lesion size Proceedings of the National Academy of Sciences of the United States of America. 99: 6280-6285. PMID 11983917 DOI: 10.1073/pnas.092324399  0.96
2002 Tabas I. Chapter 22 Lipids and atherosclerosis New Comprehensive Biochemistry. 36: 573-597.  0.96
2001 Leventhal AR, Chen W, Tall AR, Tabas I. Acid sphingomyelinase-deficient macrophages have defective cholesterol trafficking and efflux. The Journal of Biological Chemistry. 276: 44976-83. PMID 11579092 DOI: 10.1074/jbc.M106455200  0.96
2001 Kovanen PT, Tabas I. In search of a starting point Current Opinion in Lipidology. 12: 475-476. PMID 11561165 DOI: 10.1097/00041433-200110000-00001  0.96
2001 Chen W, Sun Y, Welch C, Gorelik A, Leventhal AR, Tabas I, Tall AR. Preferential ATP-binding cassette transporter A1-mediated cholesterol efflux from late endosomes/lysosomes. The Journal of Biological Chemistry. 276: 43564-9. PMID 11559713 DOI: 10.1074/jbc.M107938200  0.96
2001 Yao PM, Tabas I. Free Cholesterol Loading of Macrophages Is Associated with Widespread Mitochondrial Dysfunction and Activation of the Mitochondrial Apoptosis Pathway Journal of Biological Chemistry. 276: 42468-42476. PMID 11533046 DOI: 10.1074/jbc.M101419200  0.96
2001 Sakr SW, Eddy RJ, Barth H, Wang F, Greenberg S, Maxfield FR, Tabas I. The uptake and degradation of matrix-bound lipoproteins by macrophages require an intact actin Cytoskeleton, Rho family GTPases, and myosin ATPase activity. The Journal of Biological Chemistry. 276: 37649-58. PMID 11477084 DOI: 10.1074/jbc.M105129200  0.96
2001 Tabas I. p53 and atherosclerosis Circulation Research. 88: 747-749. PMID 11325863  0.96
2000 Marathe S, Choi Y, Leventhal AR, Tabas I. Sphingomyelinase converts lipoproteins from apolipoprotein E knockout mice into potent inducers of macrophage foam cell formation. Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 2607-13. PMID 11116060  0.96
2000 Tabas I. Cholesterol and phospholipid metabolism in macrophages Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids. 1529: 164-174. PMID 11111086 DOI: 10.1016/S1388-1981(00)00146-3  0.96
2000 Tabas I, Kovanen PT. In search of an endpoint: Editorial comment Current Opinion in Lipidology. 11: 447-450. PMID 11048886 DOI: 10.1097/00041433-200010000-00001  0.96
2000 Zhang D, Tang W, Yao PM, Yang C, Xie B, Jackowski S, Tabas I. Macrophages deficient in CTP: Phospnocholine cytidylyltransferase-α are viable under normal culture conditions but are highly susceptible to free cholesterol-induced death: Molecular genetic evidence that the induction of phosphatidylcholine biosynthesis in free cholesterol-loaded macrophages is an adaptive response Journal of Biological Chemistry. 275: 35368-35376. PMID 10944538 DOI: 10.1074/jbc.M007099200  0.96
2000 Marathe S, Miranda SR, Devlin C, Johns A, Kuriakose G, Williams KJ, Schuchman EH, Tabas I. Creation of a mouse model for non-neurological (type B) Niemann-Pick disease by stable, low level expression of lysosomal sphingomyelinase in the absence of secretory sphingomyelinase: relationship between brain intra-lysosomal enzyme activity and central nervous system function. Human Molecular Genetics. 9: 1967-76. PMID 10942425  0.96
2000 Khelef N, Soe TT, Quehenberger O, Beatini N, Tabas I, Maxfield FR. Enrichment of acyl coenzyme A:cholesterol O-acyltransferase near trans-golgi network and endocytic recycling compartment. Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 1769-76. PMID 10894815  0.96
2000 Yao PM, Tabas I. Free cholesterol loading of macrophages induces apoptosis involving the Fas pathway Journal of Biological Chemistry. 275: 23807-23813. PMID 10791964 DOI: 10.1074/jbc.M002087200  0.96
1999 Tabas I. Secretory sphingomyelinase Chemistry and Physics of Lipids. 102: 123-130. PMID 11001566 DOI: 10.1016/S0009-3084(99)00080-8  0.96
1999 Marathe S, Kuriakose G, Williams KJ, Tabas I. Sphingomyelinase, an enzyme implicated in atherogenesis, is present in atherosclerotic lesions and binds to specific components of the subendothelial extracellular matrix Arteriosclerosis, Thrombosis, and Vascular Biology. 19: 2648-2658. PMID 10559007  0.96
1999 Tabas I. Nonoxidative modifications of lipoproteins in atherogenesis Annual Review of Nutrition. 19: 123-139. PMID 10448519 DOI: 10.1146/annurev.nutr.19.1.123  0.96
1999 Sloop GD, Williams KJ, Tabas I, Weissberg PL, Bennett MR, Ross R. Atherosclerosis - An inflammatory disease [5] (multiple letters) New England Journal of Medicine. 340: 1928-1929. PMID 10375318 DOI: 10.1056/NEJM199906173402418  0.96
1999 Bakovic M, Waite K, Tang W, Tabas I, Vance DE. Transcriptional activation of the murine CTP:phosphocholine cytidylyltransferase gene (Ctpct): Combined action of upstream stimulatory and inhibitory cis-acting elements Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids. 1438: 147-165. PMID 10216289 DOI: 10.1016/S1388-1981(99)00042-6  0.96
1999 Tang W, Walsh A, Tabas I. Macrophage-targeted CTP:phosphocholine cytidylyltransferase (1-314) transgenic mice Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids. 1437: 301-316. PMID 10101264 DOI: 10.1016/S1388-1981(99)00023-2  0.96
1998 Williams KJ, Tabas I. The response-to-retention hypothesis of atherogenesis reinforced Current Opinion in Lipidology. 9: 471-474. PMID 9812202 DOI: 10.1097/00041433-199810000-00012  0.96
1998 Mukherjee S, Zha X, Tabas I, Maxfield FR. Cholesterol distribution in living cells: fluorescence imaging using dehydroergosterol as a fluorescent cholesterol analog. Biophysical Journal. 75: 1915-25. PMID 9746532 DOI: 10.1016/S0006-3495(98)77632-5  0.96
1998 Schissel SL, Keesler GA, Schuchman EH, Williams KJ, Tabas I. The cellular trafficking and zinc dependence of secretory and lysosomal sphingomyelinase, two products of the acid sphingomyelinase gene Journal of Biological Chemistry. 273: 18250-18259. PMID 9660788 DOI: 10.1074/jbc.273.29.18250  0.96
1998 Mazany KD, Peng T, Watson CE, Tabas I, Williams KJ. Human chondroitin 6-sulfotransferase: cloning, gene structure, and chromosomal localization. Biochimica Et Biophysica Acta. 1407: 92-7. PMID 9639683 DOI: 10.1016/S0925-4439(98)00028-3  0.96
1998 Khelef N, Buton X, Beatini N, Wang H, Meiner V, Chang TY, Farese RV, Maxfield FR, Tabas I. Immunolocalization of acyl-coenzyme A:cholesterol O-acyltransferase in macrophages. The Journal of Biological Chemistry. 273: 11218-24. PMID 9556612 DOI: 10.1074/jbc.273.18.11218  0.96
1998 Jeong Ts, Schissel SL, Tabas I, Pownall HJ, Tall AR, Jiang X. Increased sphingomyelin content of plasma lipoproteins in apolipoprotein E knockout mice reflects combined production and catabolic defects and enhances reactivity with mammalian sphingomyelinase. The Journal of Clinical Investigation. 101: 905-12. PMID 9466986 DOI: 10.1172/JCI870  0.96
1998 Marathe S, Schissel SL, Yellin MJ, Beatini N, Mintzer R, Williams KJ, Tabas I. Human vascular endothelial cells are a rich and regulatable source of secretory sphingomyelinase. Implications for early atherogenesis and ceramide-mediated cell signaling Journal of Biological Chemistry. 273: 4081-4088. PMID 9461601 DOI: 10.1074/jbc.273.7.4081  0.96
1998 Schissel SL, Jiang XC, Tweedie-Hardman J, Jeong TS, Camejo EH, Najib J, Rapp JH, Williams KJ, Tabas I. Secretory sphingomyelinase, a product of the acid sphingomyelinase gene, can hydrolyze atherogenic lipoproteins at neutral pH. Implications for athereosclerotic lesion development Journal of Biological Chemistry. 273: 2738-2746. PMID 9446580 DOI: 10.1074/jbc.273.5.2738  0.96
1998 Zha X, Pierini LM, Leopold PL, Skiba PJ, Tabas I, Maxfield FR. Sphingomyelinase treatment induces ATP-independent endocytosis. The Journal of Cell Biology. 140: 39-47. PMID 9425152 DOI: 10.1083/jcb.140.1.39  0.96
1998 Tabas I, Tang W. Phosphatidylcholine (pc) biosynthesis in cholesterolloaded macrophages (m+s): lessons from cell culture and transgenic mice Faseb Journal. 12.  0.96
1998 Bakovic M, Walte KA, Tang W, Tabas I, Vance DE. Regulation of the murine CTP: Phosphocholine cytidylyltransferase gene promoter by a combined action of three Spl cis-acting element Faseb Journal. 12.  0.96
1997 Tabas I. Phospholipid metabolism in cholesterol-loaded macrophages Current Opinion in Lipidology. 8: 263-267. PMID 9335949  0.96
1997 Zha X, Tabas I, Leopold PL, Jones NL, Maxfield FR. Evidence for prolonged cell-surface contact of acetyl-LDL before entry into macrophages. Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 1421-31. PMID 9261276  0.96
1997 Tabas I. Atherosclerosis: Cell biology and lipoproteins Current Opinion in Lipidology. 8. PMID 9183556 DOI: 10.1097/00041433-199704000-00016  0.96
1997 Tang W, Keesler GA, Tabas I. The structure of the gene for murine CTP:phosphocholine cytidylyltransferase, Ctpct. Relationship of exon structure to functional domains and identification of transcriptional start sites and potential upstream regulatory elements Journal of Biological Chemistry. 272: 13146-13151. PMID 9148929 DOI: 10.1074/jbc.272.20.13146  0.96
1997 Tabas I. Free cholesterol-induced cytotoxicity: A possible contributing factor to macrophage foam cell necrosis in advanced atherosclerotic lesions Trends in Cardiovascular Medicine. 7: 256-263. DOI: 10.1016/S1050-1738(97)00086-8  0.96
1997 Bakovic M, Tang W, Tabas I, Vance DE. Characterization and cyclic AMP, phorbol ester and growth factor regulation of the promoter of the murine ctp:phosphocholine cytidylyltransferase Faseb Journal. 11.  0.96
1996 Keesler GA, Gabel BR, Devlin CM, Koschinsky ML, Tabas I. The binding activity of the macrophage lipoprotein(a)/apolipoprotein(a) receptor is induced by cholesterol via a post-translational mechanism and recognizes distinct kringle domains on apolipoprotein(a). The Journal of Biological Chemistry. 271: 32096-104. PMID 8943262 DOI: 10.1074/jbc.271.50.32096  0.96
1996 Schissel SL, Tweedie-Hardman J, Rapp JH, Graham G, Williams KJ, Tabas I. Rabbit aorta and human atherosclerotic lesions hydrolyze the sphingomyelin of retained low-density lipoprotein: Proposed role for arterial-wall sphingomyelinase in subendothelial retention and aggregation of atherogenic lipoproteins Journal of Clinical Investigation. 98: 1455-1464. PMID 8823312  0.96
1996 Tabas I, Marathe S, Keesler GA, Beatini N, Shiratori Y. Evidence that the initial up-regulation of phosphatidylcholine biosynthesis in free cholesterol-loaded macrophages is an adaptive response that prevents cholesterol-induced cellular necrosis. Proposed role of an eventual failure of this response in foam cell necrosis in advanced atherosclerosis Journal of Biological Chemistry. 271: 22773-22781. PMID 8798453 DOI: 10.1074/jbc.271.37.22773  0.96
1996 Schissel SL, Schuchman EH, Williams KJ, Tabas I. Zn2+-stimulated sphingomyelinase is secreted by many cell types and is a product of the acid sphingomyelinase gene Journal of Biological Chemistry. 271: 18431-18436. PMID 8702487 DOI: 10.1074/jbc.271.31.18431  0.96
1996 Skiba PJ, Zha X, Maxfield FR, Schissel SL, Tabas I. The distal pathway of lipoprotein-induced cholesterol esterification, but not sphingomyelinase-induced cholesterol esterification, is energy-dependent. The Journal of Biological Chemistry. 271: 13392-400. PMID 8662777 DOI: 10.1074/jbc.271.23.13392  0.96
1996 Wang N, Tabas I, Winchester R, Ravalli S, Rabbani LE, Tall A. Interleukin 8 is induced by cholesterol loading of macrophages and expressed by macrophage foam cells in human atheroma. The Journal of Biological Chemistry. 271: 8837-42. PMID 8621523 DOI: 10.1074/jbc.271.15.8837  0.96
1995 Shiratori Y, Houweling M, Zha X, Tabas I. Stimulation of CTP:phosphocholine cytidylyltransferase by free cholesterol loading of macrophages involves signaling through protein dephosphorylation Journal of Biological Chemistry. 270: 29894-29903. PMID 8530387 DOI: 10.1074/jbc.270.50.29894  0.96
1995 Tabas I. The stimulation of the cholesterol esterification pathway by atherogenic lipoproteins in macrophages Current Opinion in Lipidology. 6: 260-268. PMID 8520847  0.96
1995 Williams KJ, Tabas I. The response-to-retention hypothesis of early atherogenesis Arteriosclerosis, Thrombosis, and Vascular Biology. 15: 551-562. PMID 7749869  0.96
1995 Schissel SL, Beatini N, Zha X, Maxfield FR, Tabas I. Effect and cellular site of action of cysteine protease inhibitors on the cholesterol esterification pathway in macrophages and Chinese hamster ovary cells. Biochemistry. 34: 10463-73. PMID 7654700  0.96
1994 Shiratori Y, Okwu AK, Tabas I. Free cholesterol loading of macrophages stimulates phosphatidylcholine biosynthesis and up-regulation of CTP:phosphocholine cytidylyltransferase Journal of Biological Chemistry. 269: 11337-11348. PMID 8157665  0.96
1994 Skiba PJ, Keesler GA, Tabas I. Interferon-γ down-regulates the lipoprotein(a)/apoprotein(a) receptor activity on macrophage foam cells. Evidence for disruption of ligand-induced receptor recycling by interferon-γ Journal of Biological Chemistry. 269: 23059-23067. PMID 8083207  0.96
1994 Tabas I, Zha X, Beatini N, Myers JN, Maxfield FR. The actin cytoskeleton is important for the stimulation of cholesterol esterification by atherogenic lipoproteins in macrophages. The Journal of Biological Chemistry. 269: 22547-56. PMID 8077203  0.96
1994 Keesler GA, Li Y, Skiba PJ, Fless GM, Tabas I. Macrophage foam cell lipoprotein(a)/apoprotein(a) receptor: Cell-surface localization, dependence of induction on new protein synthesis, and ligand specificity Arteriosclerosis, Thrombosis, and Vascular Biology. 14: 1337-1345. PMID 8049196  0.96
1994 Okwu AK, Xu XX, Shiratori Y, Tabas I. Regulation of the threshold for lipoprotein-induced acyl-CoA:cholesterol O-acyltransferase stimulation in macrophages by cellular sphingomyelin content Journal of Lipid Research. 35: 644-655. PMID 8006519  0.96
1994 Granot E, Schwiegelshohn B, Tabas I, Gorecki M, Vogel T, Carpentier YA, Deckelbaum RJ. Effects of particle size on cell uptake of model triglyceride-rich particles with and without apoprotein E. Biochemistry. 33: 15190-7. PMID 7999779  0.96
1993 Bottalico LA, Keesler GA, Fless GM, Tabas I. Cholesterol loading of macrophages leads to marked enhancement of native lipoprotein(a) and apoprotein(a) internalization and degradation Journal of Biological Chemistry. 268: 8569-8573. PMID 8473302  0.96
1993 Bottalico LA, Kendrick NC, Keller A, Li Y, Tabas I. Cholesteryl ester loading of mouse peritoneal macrophages is associated with changes in the expression or modification of specific cellular proteins, including increase in an α-enolase isoform Arteriosclerosis, Thrombosis, and Vascular Biology. 13: 264-275. PMID 8427861  0.96
1993 Tabas I, Li Y, Brocia RW, Xu SW, Swenson TL, Williams KJ. Lipoprotein lipase and sphingomyelinase synergistically enhance the association of atherogenic lipoproteins with smooth muscle cells and extracellular matrix: A possible mechanism for low density lipoprotein and lipoprotein(a) retention and macrophage foam cell formation Journal of Biological Chemistry. 268: 20419-20432. PMID 8376399  0.96
1993 Myers JN, Tabas I, Jones NL, Maxfield FR. Beta-very low density lipoprotein is sequestered in surface-connected tubules in mouse peritoneal macrophages. The Journal of Cell Biology. 123: 1389-402. PMID 8253839  0.96
1991 Xu XX, Tabas I. Lipoproteins activate acyl-coenzyme A:Cholesterol acyltransferase in macrophages only after cellular cholesterol pools are expanded to a critical threshold level Journal of Biological Chemistry. 266: 17040-17048. PMID 1894601  0.96
1991 Tabas I, Beatini N, Chen LL, Su WC, Puar MS, Dugar S, Clader JW. Identification and characterization of an acyl-CoA:triterpene acyltransferase activity in rabbit and human tissues Journal of Lipid Research. 32: 1689-1698. PMID 1797948  0.96
1991 Xu XX, Tabas I. Sphingomyelinase enhances low density lipoprotein uptake and ability to induce cholesteryl ester accumulation in macrophages Journal of Biological Chemistry. 266: 24849-24858. PMID 1761578  0.96
1991 Bottalico LA, Wager RE, Agellon LB, Assoian RK, Tabas I. Transforming growth factor-beta 1 inhibits scavenger receptor activity in THP-1 human macrophages. The Journal of Biological Chemistry. 266: 22866-71. PMID 1744079  0.96
1991 Hussain MM, Maxfield FR, Más-Oliva J, Tabas I, Ji ZS, Innerarity TL, Mahley RW. Clearance of chylomicron remnants by the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor. The Journal of Biological Chemistry. 266: 13936-40. PMID 1713211  0.96
1991 Tabas I, Myers JN, Innerarity TL, Xu XX, Arnold K, Boyles J, Maxfield FR. The influence of particle size and multiple apoprotein E-receptor interactions on the endocytic targeting of beta-VLDL in mouse peritoneal macrophages. The Journal of Cell Biology. 115: 1547-60. PMID 1661729  0.96
1990 Tabas I, Lim S, Xu XX, Maxfield FR. Endocytosed beta-VLDL and LDL are delivered to different intracellular vesicles in mouse peritoneal macrophages. The Journal of Cell Biology. 111: 929-40. PMID 2391369  0.96
1989 Khoo JC, Miller E, McLoughlin P, Tabas I, Rosoff WJ. Cholesterol esterification as a limiting factor in accumulation of cell cholesterol: a comparison of two J774 macrophage cell lines. Biochimica Et Biophysica Acta. 1012: 215-7. PMID 2742881 DOI: 10.1016/0167-4889(89)90099-2  0.96
1989 Tabas I, Feinmark SJ, Beatini N. The reactivity of desmosterol and other shellfish- and xanthomatosis-associated sterols in the macrophage sterol esterification reaction Journal of Clinical Investigation. 84: 1713-1721. PMID 2592557  0.96
1988 Tabas I, Rosoff WJ, Boykow GC. Acyl coenzyme A:cholesterol acyl transferase in macrophages utilizes a cellular pool of cholesterol oxidase-accessible cholesterol as substrate. The Journal of Biological Chemistry. 263: 1266-72. PMID 3422077  0.96
1987 Tabas I, Boykow GC, Tall AR. Foam cell-forming J774 macrophages have markedly elevated acyl coenzyme A:cholesterol acyl transferase activity compared with mouse peritoneal macrophages in the presence of low density lipoprotein (LDL) despite similar LDL receptor activity. The Journal of Clinical Investigation. 79: 418-26. PMID 3805276 DOI: 10.1172/JCI112828  0.96
1987 Tabas I, Boykow GC. Protein synthesis inhibition in mouse peritoneal macrophages results in increased acyl coenzyme A:cholesterol acyl transferase activity and cholesteryl ester accumulation in the presence of native low density lipoprotein Journal of Biological Chemistry. 262: 12175-12181. PMID 3624250  0.96
1987 Tall A, Granot E, Brocia R, Tabas I, Hesler C, Williams K, Denke M. Accelerated transfer of cholesteryl esters in dyslipidemic plasma. Role of cholesteryl ester transfer protein. The Journal of Clinical Investigation. 79: 1217-25. PMID 3558822 DOI: 10.1172/JCI112940  0.96
1987 Granot E, Tabas I, Tall AR. Human plasma cholesteryl ester transfer protein enhances the transfer of cholesteryl ester from high density lipoproteins into cultured HepG2 cells. The Journal of Biological Chemistry. 262: 3482-7. PMID 3029115  0.96
1986 Tabas I, Weiland DA, Tall AR. Inhibition of acyl coenzyme A:cholesterol acyl transferase in J774 macrophages enhances down-regulation of the low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl-coenzyme A reductase and prevents low density lipoprotein-induced cholesterol accumulation. The Journal of Biological Chemistry. 261: 3147-55. PMID 3949765  0.96
1986 Tall AR, Tabas I, Williams KJ. Lipoprotein-liposome interactions. Methods in Enzymology. 128: 647-57. PMID 3724528  0.96
1986 Williams KJ, Tall AR, Tabas I, Blum C. Recognition of vesicular lipoproteins by the apolipoprotein B,E receptor of cultured fibroblasts. Journal of Lipid Research. 27: 892-900. PMID 3021887  0.96
1986 Tall AR, Tabas I, Williams KJ. Lipoprotein-liposome interactions Methods in Enzymology. 647-657.  0.96
1985 Tabas I, Weiland DA, Tall AR. Unmodified low density lipoprotein causes cholesteryl ester accumulation in J774 macrophages. Proceedings of the National Academy of Sciences of the United States of America. 82: 416-20. PMID 3855559  0.96
1984 Tabas I, Tall AR. Mechanism of the association of HDL3 with endothelial cells, smooth muscle cells, and fibroblasts. Evidence against the role of specific ligand and receptor proteins. The Journal of Biological Chemistry. 259: 13897-905. PMID 6438086  0.96
1983 Varki AP, Reitman ML, Tabas I, Kornfeld S. Studies of the synthesis, structure and function of the phosphorylated oligosaccharides of lysosomal enzymes Journal of Biosciences. 5: 101-104. DOI: 10.1007/BF02702980  0.96
1982 Tabas I, Kornfeld S. [37] N-asparagine-linked oligosaccharides: Processing Methods in Enzymology. 83: 416-429. DOI: 10.1016/0076-6879(82)83039-5  0.96
1980 Tabas I, Kornfeld S. Biosynthetic intermediates of beta-glucuronidase contain high mannose oligosaccharides with blocked phosphate residues Journal of Biological Chemistry. 255: 6633-6639. PMID 7391040  0.96
1979 Tabas I, Kornfeld S. Purification and characterization of a rat liver Golgi alpha-mannosidase capable of processing asparagine-linked oligosaccharides Journal of Biological Chemistry. 254: 11655-11663. PMID 500665  0.96
1978 Tabas I, Kornfeld S. The synthesis of complex-type oligosaccharides. III. Identification of an alpha-D-mannosidase activity involved in a late stage of processing of complex-type oligosaccharides Journal of Biological Chemistry. 253: 7779-7786. PMID 212436  0.96
1978 Kornfeld S, Li E, Tabas I. The synthesis of complex-type oligosaccharides. II. Characterization of the processing intermediates in the synthesis of the complex oligosaccharide units of the vesicular stomatitis virus G protein Journal of Biological Chemistry. 253: 7771-7778. PMID 212435  0.96
1978 Li E, Tabas I, Kornfeld S. The synthesis of complex-type oligosaccharides. I. Structure of the lipid-linked oligosaccharide precursor of the complex-type oligosaccharides of the vesicular stomatitis virus G protein Journal of Biological Chemistry. 253: 7762-7770. PMID 212434  0.96
1978 Tabas I, Schlesinger S, Kornfeld S. Processing of high mannose oligosaccharides to form complex type oligosaccharides on the newly synthesized polypeptides of the vesicular stomatitis virus G protein and the IgG heavy chain Journal of Biological Chemistry. 253: 716-722. PMID 202596  0.96
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