Alan Tall, M.D. - Publications

Department of Medicine Columbia University, New York, NY 

129 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Shea S, Stein JH, Jorgensen NW, McClelland RL, Tascau L, Shrager S, Heinecke JW, Yvan-Charvet L, Tall AR. Cholesterol Mass Efflux Capacity, Incident Cardiovascular Disease, and Progression of Carotid Plaque. Arteriosclerosis, Thrombosis, and Vascular Biology. 39: 89-96. PMID 30580560 DOI: 10.1161/ATVBAHA.118.311366  0.52
2018 Thomas DG, Doran AC, Fotakis P, Westerterp M, Antonson P, Jiang H, Jiang XC, Gustafsson JÅ, Tabas I, Tall AR. LXR Suppresses Inflammatory Gene Expression and Neutrophil Migration through cis-Repression and Cholesterol Efflux. Cell Reports. 25: 3774-3785.e4. PMID 30590048 DOI: 10.1016/j.celrep.2018.11.100  0.92
2018 Wang W, Liu W, Fidler T, Wang Y, Tang Y, Woods B, Welch C, Cai B, Silvestre-Roig C, Ai D, Yang YG, Hidalgo A, Soehnlein O, Tabas I, Levine RL, ... Tall AR, et al. Macrophage Inflammation, Erythrophagocytosis, and Accelerated Atherosclerosis in Jak2 Mice. Circulation Research. 123: e35-e47. PMID 30571460 DOI: 10.1161/CIRCRESAHA.118.313283  0.92
2018 Molusky MM, Hsieh J, Lee SX, Ramakrishnan R, Tascau L, Haeusler RA, Accili D, Tall AR. Metformin and AMP Kinase Activation Increase Expression of the Sterol Transporters ABCG5/8 (ATP-Binding Cassette Transporter G5/G8) With Potential Antiatherogenic Consequences. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 29853564 DOI: 10.1161/ATVBAHA.118.311212  0.52
2018 Westerterp M, Fotakis P, Ouimet M, Bochem AE, Zhang H, Molusky MM, Wang W, Abramowicz S, la Bastide-van Gemert S, Wang N, Welch CL, Reilly MP, Stroes ES, Moore KJ, Tall AR. Cholesterol Efflux Pathways Suppress Inflammasome Activation, NETosis and Atherogenesis. Circulation. PMID 29588315 DOI: 10.1161/CIRCULATIONAHA.117.032636  0.52
2017 Koseki M, Hsieh J, Molusky M, Yakushiji E, Westerterp M, Ichi I, Abramowicz S, Tascau L, Welch C, Takiguchi S, Iqbal J, Sakata Y, Yamashita S, Hussain M, Rader D, ... Tall A, et al. The role of TTC39B in atherosclerosis and non-alcoholic steatohepatitis. Atherosclerosis. 263: e82-e83. PMID 29366239 DOI: 10.1016/j.atherosclerosis.2017.06.268  0.48
2017 Liu DJ, Peloso GM, Yu H, Butterworth AS, Wang X, Mahajan A, Saleheen D, Emdin C, Alam D, Alves AC, Amouyel P, Di Angelantonio E, Arveiler D, Assimes TL, Auer PL, ... ... Tall AR, et al. Exome-wide association study of plasma lipids in >300,000 individuals. Nature Genetics. PMID 29083408 DOI: 10.1038/ng.3977  0.52
2017 Doran AC, Ozcan L, Cai B, Zheng Z, Fredman G, Rymond CC, Dorweiler B, Sluimer JC, Hsieh J, Kuriakose G, Tall AR, Tabas I. CAMKIIγ suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosis. The Journal of Clinical Investigation. PMID 28972541 DOI: 10.1172/JCI94735  0.92
2017 Wang Y, Wang W, Wang N, Tall AR, Tabas I. Mitochondrial Oxidative Stress Promotes Atherosclerosis and Neutrophil Extracellular Traps in Aged Mice. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 28596373 DOI: 10.1161/ATVBAHA.117.309580  0.92
2017 Westerterp M, Gautier EL, Ganda A, Molusky MM, Wang W, Fotakis P, Wang N, Randolph GJ, D'Agati VD, Yvan-Charvet L, Tall AR. Cholesterol Accumulation in Dendritic Cells Links the Inflammasome to Acquired Immunity. Cell Metabolism. PMID 28479366 DOI: 10.1016/j.cmet.2017.04.005  0.52
2017 Ganda A, Yvan-Charvet L, Zhang Y, Lai EJ, Regunathan-Shenk R, Hussain FN, Avasare R, Chakraborty B, Febus AJ, Vernocchi L, Lantigua R, Wang Y, Shi X, Hsieh J, Murphy AJ, ... ... Tall AR, et al. Plasma metabolite profiles, cellular cholesterol efflux, and non-traditional cardiovascular risk in patients with CKD. Journal of Molecular and Cellular Cardiology. PMID 28478047 DOI: 10.1016/j.yjmcc.2017.05.001  0.52
2017 Wang N, Tall AR. A New Approach to PCSK9 Therapeutics. Circulation Research. PMID 28264867 DOI: 10.1161/CIRCRESAHA.117.310610  0.52
2016 Wang W, Tang Y, Wang Y, Tascau L, Balcerek J, Tong W, Levine R, Welch CL, Tall AR, Wang N. LNK/SH2B3 Loss of Function Promotes Atherosclerosis and Thrombosis. Circulation Research. PMID 27430239 DOI: 10.1161/CIRCRESAHA.116.308955  0.52
2016 Hsieh J, Koseki M, Molusky MM, Yakushiji E, Ichi I, Westerterp M, Iqbal J, Chan RB, Abramowicz S, Tascau L, Takiguchi S, Yamashita S, Welch CL, Di Paolo G, Hussain MM, ... ... Tall AR, et al. TTC39B deficiency stabilizes LXR reducing both atherosclerosis and steatohepatitis. Nature. PMID 27383786 DOI: 10.1038/nature18628  0.92
2016 Westerterp M, Wang N, Tall AR. High-Density Lipoproteins, Endothelial Function, and Mendelian Randomization. Circulation Research. 119: 13-5. PMID 27340266 DOI: 10.1161/CIRCRESAHA.116.309116  0.52
2016 Westerterp M, Tsuchiya K, Tattersall IW, Fotakis P, Bochem AE, Molusky MM, Ntonga V, Abramowicz S, Parks JS, Welch CL, Kitajewski J, Accili D, Tall AR. Deficiency of ATP-Binding Cassette Transporters A1 and G1 in Endothelial Cells Accelerates Atherosclerosis in Mice. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 27199450 DOI: 10.1161/ATVBAHA.115.306670  0.52
2016 Wang W, Oh S, Koester M, Abramowicz S, Wang N, Tall AR, Welch CL. Enhanced Megakaryopoiesis and Platelet Activity in Hypercholesterolemic, B6-Ldlr-/-,Cdkn2a-Deficient Mice. Circulation. Cardiovascular Genetics. PMID 27098250 DOI: 10.1161/CIRCGENETICS.115.001294  0.52
2016 Wang N, Tall AR. Cholesterol in platelet biogenesis and activation. Blood. PMID 26929273 DOI: 10.1182/blood-2016-01-631259  0.52
2015 Bochem AE, van der Valk FM, Tolani S, Stroes ES, Westerterp M, Tall AR. Increased Systemic and Plaque Inflammation in ABCA1 Mutation Carriers With Attenuation by Statins. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 1663-9. PMID 26109739 DOI: 10.1161/ATVBAHA.114.304959  0.92
2015 Westerterp M, Tall AR. SORTILIN: many headed hydra. Circulation Research. 116: 764-6. PMID 25722435 DOI: 10.1161/CIRCRESAHA.115.306036  0.92
2015 Tall AR, Yvan-Charvet L. Cholesterol, inflammation and innate immunity. Nature Reviews. Immunology. 15: 104-16. PMID 25614320 DOI: 10.1038/nri3793  0.92
2014 Murphy AJ, Dragoljevic D, Tall AR. Cholesterol efflux pathways regulate myelopoiesis: a potential link to altered macrophage function in atherosclerosis. Frontiers in Immunology. 5: 490. PMID 25352845 DOI: 10.3389/fimmu.2014.00490  0.92
2014 Nagareddy PR, Kraakman M, Masters SL, Stirzaker RA, Gorman DJ, Grant RW, Dragoljevic D, Hong ES, Abdel-Latif A, Smyth SS, Choi SH, Korner J, Bornfeldt KE, Fisher EA, Dixit VD, ... Tall AR, et al. Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity. Cell Metabolism. 19: 821-35. PMID 24807222 DOI: 10.1016/j.cmet.2014.03.029  0.92
2014 Ai D, Jiang H, Westerterp M, Murphy AJ, Wang M, Ganda A, Abramowicz S, Welch C, Almazan F, Zhu Y, Miller YI, Tall AR. Disruption of mammalian target of rapamycin complex 1 in macrophages decreases chemokine gene expression and atherosclerosis. Circulation Research. 114: 1576-84. PMID 24687132 DOI: 10.1161/CIRCRESAHA.114.302313  0.92
2014 Wang M, Subramanian M, Abramowicz S, Murphy AJ, Gonen A, Witztum J, Welch C, Tabas I, Westerterp M, Tall AR. Interleukin-3/granulocyte macrophage colony-stimulating factor receptor promotes stem cell expansion, monocytosis, and atheroma macrophage burden in mice with hematopoietic ApoE deficiency. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 976-84. PMID 24651678 DOI: 10.1161/ATVBAHA.113.303097  0.92
2014 Fruchart JC, Davignon J, Hermans MP, Al-Rubeaan K, Amarenco P, Assmann G, Barter P, Betteridge J, Bruckert E, Cuevas A, Farnier M, Ferrannini E, Fioretto P, Genest J, Ginsberg HN, ... ... Tall A, et al. Residual macrovascular risk in 2013: what have we learned? Cardiovascular Diabetology. 13: 26. PMID 24460800 DOI: 10.1186/1475-2840-13-26  0.92
2014 Murphy AJ, Tall AR. Proliferating macrophages populate established atherosclerotic lesions. Circulation Research. 114: 236-8. PMID 24436425 DOI: 10.1161/CIRCRESAHA.113.302813  0.92
2014 Westerterp M, Bochem AE, Yvan-Charvet L, Murphy AJ, Wang N, Tall AR. ATP-binding cassette transporters, atherosclerosis, and inflammation. Circulation Research. 114: 157-70. PMID 24385509 DOI: 10.1161/CIRCRESAHA.114.300738  0.92
2014 Kappus MS, Murphy AJ, Abramowicz S, Ntonga V, Welch CL, Tall AR, Westerterp M. Activation of liver X receptor decreases atherosclerosis in Ldlr⁻/⁻ mice in the absence of ATP-binding cassette transporters A1 and G1 in myeloid cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 279-84. PMID 24311381 DOI: 10.1161/ATVBAHA.113.302781  0.92
2013 Rosenson RS, Brewer HB, Ansell B, Barter P, Chapman MJ, Heinecke JW, Kontush A, Tall AR, Webb NR. Translation of high-density lipoprotein function into clinical practice: current prospects and future challenges. Circulation. 128: 1256-67. PMID 24019446 DOI: 10.1161/CIRCULATIONAHA.113.000962  0.92
2013 Tolani S, Pagler TA, Murphy AJ, Bochem AE, Abramowicz S, Welch C, Nagareddy PR, Holleran S, Hovingh GK, Kuivenhoven JA, Tall AR. Hypercholesterolemia and reduced HDL-C promote hematopoietic stem cell proliferation and monocytosis: studies in mice and FH children. Atherosclerosis. 229: 79-85. PMID 23684512 DOI: 10.1016/j.atherosclerosis.2013.03.031  0.92
2013 Ishibashi M, Sayers S, D'Armiento JM, Tall AR, Welch CL. TLR3 deficiency protects against collagen degradation and medial destruction in murine atherosclerotic plaques. Atherosclerosis. 229: 52-61. PMID 23676255 DOI: 10.1016/j.atherosclerosis.2013.03.035  0.92
2013 Nagareddy PR, Murphy AJ, Stirzaker RA, Hu Y, Yu S, Miller RG, Ramkhelawon B, Distel E, Westerterp M, Huang LS, Schmidt AM, Orchard TJ, Fisher EA, Tall AR, Goldberg IJ. Hyperglycemia promotes myelopoiesis and impairs the resolution of atherosclerosis. Cell Metabolism. 17: 695-708. PMID 23663738 DOI: 10.1016/j.cmet.2013.04.001  0.92
2013 Murphy AJ, Funt S, Gorman D, Tall AR, Wang N. Pegylation of high-density lipoprotein decreases plasma clearance and enhances antiatherogenic activity. Circulation Research. 113: e1-9. PMID 23613182 DOI: 10.1161/CIRCRESAHA.113.301112  0.92
2013 Murphy AJ, Bijl N, Yvan-Charvet L, Welch CB, Bhagwat N, Reheman A, Wang Y, Shaw JA, Levine RL, Ni H, Tall AR, Wang N. Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis. Nature Medicine. 19: 586-94. PMID 23584088 DOI: 10.1038/nm.3150  0.92
2013 Westerterp M, Murphy AJ, Wang M, Pagler TA, Vengrenyuk Y, Kappus MS, Gorman DJ, Nagareddy PR, Zhu X, Abramowicz S, Parks JS, Welch C, Fisher EA, Wang N, Yvan-Charvet L, ... Tall AR, et al. Deficiency of ATP-binding cassette transporters A1 and G1 in macrophages increases inflammation and accelerates atherosclerosis in mice. Circulation Research. 112: 1456-65. PMID 23572498 DOI: 10.1161/CIRCRESAHA.113.301086  0.92
2013 Martel C, Li W, Fulp B, Platt AM, Gautier EL, Westerterp M, Bittman R, Tall AR, Chen SH, Thomas MJ, Kreisel D, Swartz MA, Sorci-Thomas MG, Randolph GJ. Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice. The Journal of Clinical Investigation. 123: 1571-9. PMID 23524964 DOI: 10.1172/JCI63685  0.92
2013 Tsuchiya K, Westerterp M, Murphy AJ, Subramanian V, Ferrante AW, Tall AR, Accili D. Expanded granulocyte/monocyte compartment in myeloid-specific triple FoxO knockout increases oxidative stress and accelerates atherosclerosis in mice. Circulation Research. 112: 992-1003. PMID 23420833 DOI: 10.1161/CIRCRESAHA.112.300749  0.92
2013 Ganda A, Magnusson M, Yvan-Charvet L, Hedblad B, Engström G, Ai D, Wang TJ, Gerszten RE, Melander O, Tall AR. Mild renal dysfunction and metabolites tied to low HDL cholesterol are associated with monocytosis and atherosclerosis. Circulation. 127: 988-96. PMID 23378299 DOI: 10.1161/CIRCULATIONAHA.112.000682  0.92
2013 Gautier EL, Westerterp M, Bhagwat N, Cremers S, Shih A, Abdel-Wahab O, Lütjohann D, Randolph GJ, Levine RL, Tall AR, Yvan-Charvet L. HDL and Glut1 inhibition reverse a hypermetabolic state in mouse models of myeloproliferative disorders. The Journal of Experimental Medicine. 210: 339-53. PMID 23319699 DOI: 10.1084/jem.20121357  0.92
2012 Tall AR, Yvan-Charvet L, Westerterp M, Murphy AJ. Cholesterol efflux: a novel regulator of myelopoiesis and atherogenesis. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 2547-52. PMID 23077140 DOI: 10.1161/ATVBAHA.112.300134  0.92
2012 Rader DJ, Tall AR. The not-so-simple HDL story: Is it time to revise the HDL cholesterol hypothesis? Nature Medicine. 18: 1344-6. PMID 22961164 DOI: 10.1038/nm.2937  0.92
2012 Westerterp M, Gourion-Arsiquaud S, Murphy AJ, Shih A, Cremers S, Levine RL, Tall AR, Yvan-Charvet L. Regulation of hematopoietic stem and progenitor cell mobilization by cholesterol efflux pathways. Cell Stem Cell. 11: 195-206. PMID 22862945 DOI: 10.1016/j.stem.2012.04.024  0.92
2012 Liang CP, Han S, Li G, Tabas I, Tall AR. Impaired MEK signaling and SERCA expression promote ER stress and apoptosis in insulin-resistant macrophages and are reversed by exenatide treatment. Diabetes. 61: 2609-20. PMID 22751695 DOI: 10.2337/db11-1415  0.92
2012 Strong A, Ding Q, Edmondson AC, Millar JS, Sachs KV, Li X, Kumaravel A, Wang MY, Ai D, Guo L, Alexander ET, Nguyen D, Lund-Katz S, Phillips MC, Morales CR, ... Tall AR, et al. Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism. The Journal of Clinical Investigation. 122: 2807-16. PMID 22751103 DOI: 10.1172/JCI63563  0.92
2012 Rosenson RS, Brewer HB, Davidson WS, Fayad ZA, Fuster V, Goldstein J, Hellerstein M, Jiang XC, Phillips MC, Rader DJ, Remaley AT, Rothblat GH, Tall AR, Yvan-Charvet L. Cholesterol efflux and atheroprotection: advancing the concept of reverse cholesterol transport. Circulation. 125: 1905-19. PMID 22508840 DOI: 10.1161/CIRCULATIONAHA.111.066589  0.92
2012 Ai D, Baez JM, Jiang H, Conlon DM, Hernandez-Ono A, Frank-Kamenetsky M, Milstein S, Fitzgerald K, Murphy AJ, Woo CW, Strong A, Ginsberg HN, Tabas I, Rader DJ, Tall AR. Activation of ER stress and mTORC1 suppresses hepatic sortilin-1 levels in obese mice. The Journal of Clinical Investigation. 122: 1677-87. PMID 22466652 DOI: 10.1172/JCI61248  0.92
2012 Ai D, Chen C, Han S, Ganda A, Murphy AJ, Haeusler R, Thorp E, Accili D, Horton JD, Tall AR. Regulation of hepatic LDL receptors by mTORC1 and PCSK9 in mice. The Journal of Clinical Investigation. 122: 1262-70. PMID 22426206 DOI: 10.1172/JCI61919  0.92
2012 Tsuchiya K, Tanaka J, Shuiqing Y, Welch CL, DePinho RA, Tabas I, Tall AR, Goldberg IJ, Accili D. FoxOs integrate pleiotropic actions of insulin in vascular endothelium to protect mice from atherosclerosis. Cell Metabolism. 15: 372-81. PMID 22405072 DOI: 10.1016/j.cmet.2012.01.018  0.92
2012 Murphy AJ, Westerterp M, Yvan-Charvet L, Tall AR. Anti-atherogenic mechanisms of high density lipoprotein: effects on myeloid cells. Biochimica Et Biophysica Acta. 1821: 513-21. PMID 21864714 DOI: 10.1016/j.bbalip.2011.08.003  0.92
2011 Murphy AJ, Akhtari M, Tolani S, Pagler T, Bijl N, Kuo CL, Wang M, Sanson M, Abramowicz S, Welch C, Bochem AE, Kuivenhoven JA, Yvan-Charvet L, Tall AR. ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice. The Journal of Clinical Investigation. 121: 4138-49. PMID 21968112 DOI: 10.1172/JCI57559  0.92
2011 Tsuchiya K, Banks AS, Liang CP, Tabas I, Tall AR, Accili D. Homozygosity for an allele encoding deacetylated FoxO1 protects macrophages from cholesterol-induced inflammation without increasing apoptosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 2920-8. PMID 21940942 DOI: 10.1161/ATVBAHA.110.219477  0.92
2011 Kuo CL, Murphy AJ, Sayers S, Li R, Yvan-Charvet L, Davis JZ, Krishnamurthy J, Liu Y, Puig O, Sharpless NE, Tall AR, Welch CL. Cdkn2a is an atherosclerosis modifier locus that regulates monocyte/macrophage proliferation. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 2483-92. PMID 21868699 DOI: 10.1161/ATVBAHA.111.234492  0.92
2011 Jung UJ, Millman PN, Tall AR, Deckelbaum RJ. n-3 fatty acids ameliorate hepatic steatosis and dysfunction after LXR agonist ingestion in mice. Biochimica Et Biophysica Acta. 1811: 491-7. PMID 21704188 DOI: 10.1016/j.bbalip.2011.06.003  0.92
2011 Tall AR, Ai D. Sorting out sortilin. Circulation Research. 108: 158-60. PMID 21252148 DOI: 10.1161/RES.0b013e31820d7daa  0.92
2011 Pagler TA, Wang M, Mondal M, Murphy AJ, Westerterp M, Moore KJ, Maxfield FR, Tall AR. Deletion of ABCA1 and ABCG1 impairs macrophage migration because of increased Rac1 signaling. Circulation Research. 108: 194-200. PMID 21148432 DOI: 10.1161/CIRCRESAHA.110.228619  0.92
2010 Tall AR. Functions of cholesterol ester transfer protein and relationship to coronary artery disease risk. Journal of Clinical Lipidology. 4: 389-93. PMID 21076631 DOI: 10.1016/j.jacl.2010.08.006  0.92
2010 Terasaka N, Westerterp M, Koetsveld J, Fernández-Hernando C, Yvan-Charvet L, Wang N, Sessa WC, Tall AR. ATP-binding cassette transporter G1 and high-density lipoprotein promote endothelial NO synthesis through a decrease in the interaction of caveolin-1 and endothelial NO synthase. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 2219-25. PMID 20798376 DOI: 10.1161/ATVBAHA.110.213215  0.92
2010 Westerterp M, Koetsveld J, Yu S, Han S, Li R, Goldberg IJ, Welch CL, Tall AR. Increased atherosclerosis in mice with vascular ATP-binding cassette transporter G1 deficiency--brief report. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 2103-5. PMID 20705913 DOI: 10.1161/ATVBAHA.110.212985  0.92
2010 Ishibashi M, Masson D, Westerterp M, Wang N, Sayers S, Li R, Welch CL, Tall AR. Reduced VLDL clearance in Apoe(-/-)Npc1(-/-) mice is associated with increased Pcsk9 and Idol expression and decreased hepatic LDL-receptor levels. Journal of Lipid Research. 51: 2655-63. PMID 20562239 DOI: 10.1194/jlr.M006163  0.92
2010 Yvan-Charvet L, Pagler T, Gautier EL, Avagyan S, Siry RL, Han S, Welch CL, Wang N, Randolph GJ, Snoeck HW, Tall AR. ATP-binding cassette transporters and HDL suppress hematopoietic stem cell proliferation. Science (New York, N.Y.). 328: 1689-93. PMID 20488992 DOI: 10.1126/science.1189731  0.92
2010 Yvan-Charvet L, Kling J, Pagler T, Li H, Hubbard B, Fisher T, Sparrow CP, Taggart AK, Tall AR. Cholesterol efflux potential and antiinflammatory properties of high-density lipoprotein after treatment with niacin or anacetrapib. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 1430-8. PMID 20448206 DOI: 10.1161/ATVBAHA.110.207142  0.92
2010 Yvan-Charvet L, Pagler TA, Seimon TA, Thorp E, Welch CL, Witztum JL, Tabas I, Tall AR. ABCA1 and ABCG1 protect against oxidative stress-induced macrophage apoptosis during efferocytosis. Circulation Research. 106: 1861-9. PMID 20431058 DOI: 10.1161/CIRCRESAHA.110.217281  0.92
2010 Tabas I, Tall A, Accili D. The impact of macrophage insulin resistance on advanced atherosclerotic plaque progression. Circulation Research. 106: 58-67. PMID 20056946 DOI: 10.1161/CIRCRESAHA.109.208488  0.92
2010 Yvan-Charvet L, Wang N, Tall AR. Role of HDL, ABCA1, and ABCG1 transporters in cholesterol efflux and immune responses. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 139-43. PMID 19797709 DOI: 10.1161/ATVBAHA.108.179283  0.52
2009 Li S, Sun Y, Liang CP, Thorp EB, Han S, Jehle AW, Saraswathi V, Pridgen B, Kanter JE, Li R, Welch CL, Hasty AH, Bornfeldt KE, Breslow JL, Tabas I, ... Tall AR, et al. Defective phagocytosis of apoptotic cells by macrophages in atherosclerotic lesions of ob/ob mice and reversal by a fish oil diet. Circulation Research. 105: 1072-82. PMID 19834009 DOI: 10.1161/CIRCRESAHA.109.199570  0.92
2009 Masson D, Koseki M, Ishibashi M, Larson CJ, Miller SG, King BD, Tall AR. Increased HDL cholesterol and apoA-I in humans and mice treated with a novel SR-BI inhibitor. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 2054-60. PMID 19815817 DOI: 10.1161/ATVBAHA.109.191320  0.92
2009 Seimon TA, Wang Y, Han S, Senokuchi T, Schrijvers DM, Kuriakose G, Tall AR, Tabas IA. Macrophage deficiency of p38alpha MAPK promotes apoptosis and plaque necrosis in advanced atherosclerotic lesions in mice. The Journal of Clinical Investigation. 119: 886-98. PMID 19287091 DOI: 10.1172/JCI37262  0.44
2009 Han S, Liang CP, Westerterp M, Senokuchi T, Welch CL, Wang Q, Matsumoto M, Accili D, Tall AR. Hepatic insulin signaling regulates VLDL secretion and atherogenesis in mice. The Journal of Clinical Investigation. 119: 1029-41. PMID 19273907 DOI: 10.1172/JCI36523  0.52
2009 Sun Y, Ishibashi M, Seimon T, Lee M, Sharma SM, Fitzgerald KA, Samokhin AO, Wang Y, Sayers S, Aikawa M, Jerome WG, Ostrowski MC, Bromme D, Libby P, Tabas IA, ... ... Tall AR, et al. Free cholesterol accumulation in macrophage membranes activates Toll-like receptors and p38 mitogen-activated protein kinase and induces cathepsin K. Circulation Research. 104: 455-65. PMID 19122179 DOI: 10.1161/CIRCRESAHA.108.182568  0.48
2009 Masson D, Jiang XC, Lagrost L, Tall AR. The role of plasma lipid transfer proteins in lipoprotein metabolism and atherogenesis. Journal of Lipid Research. 50: S201-6. PMID 19023137 DOI: 10.1194/jlr.R800061-JLR200  0.36
2008 Terasaka N, Yu S, Yvan-Charvet L, Wang N, Mzhavia N, Langlois R, Pagler T, Li R, Welch CL, Goldberg IJ, Tall AR. ABCG1 and HDL protect against endothelial dysfunction in mice fed a high-cholesterol diet. The Journal of Clinical Investigation. 118: 3701-13. PMID 18924609 DOI: 10.1172/JCI35470  0.52
2008 Yvan-Charvet L, Welch C, Pagler TA, Ranalletta M, Lamkanfi M, Han S, Ishibashi M, Li R, Wang N, Tall AR. Increased inflammatory gene expression in ABC transporter-deficient macrophages: free cholesterol accumulation, increased signaling via toll-like receptors, and neutrophil infiltration of atherosclerotic lesions. Circulation. 118: 1837-47. PMID 18852364 DOI: 10.1161/CIRCULATIONAHA.108.793869  0.92
2008 Seidelmann SB, Kuo C, Pleskac N, Molina J, Sayers S, Li R, Zhou J, Johnson P, Braun K, Chan C, Teupser D, Breslow JL, Wight TN, Tall AR, Welch CL. Athsq1 is an atherosclerosis modifier locus with dramatic effects on lesion area and prominent accumulation of versican. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 2180-6. PMID 18818413 DOI: 10.1161/ATVBAHA.108.176800  0.92
2008 Senokuchi T, Liang CP, Seimon TA, Han S, Matsumoto M, Banks AS, Paik JH, DePinho RA, Accili D, Tabas I, Tall AR. Forkhead transcription factors (FoxOs) promote apoptosis of insulin-resistant macrophages during cholesterol-induced endoplasmic reticulum stress. Diabetes. 57: 2967-76. PMID 18728232 DOI: 10.2337/db08-0520  0.92
2008 Tall AR, Yvan-Charvet L, Terasaka N, Pagler T, Wang N. HDL, ABC transporters, and cholesterol efflux: implications for the treatment of atherosclerosis. Cell Metabolism. 7: 365-75. PMID 18460328 DOI: 10.1016/j.cmet.2008.03.001  0.52
2008 Wang N, Yvan-Charvet L, Lütjohann D, Mulder M, Vanmierlo T, Kim TW, Tall AR. ATP-binding cassette transporters G1 and G4 mediate cholesterol and desmosterol efflux to HDL and regulate sterol accumulation in the brain. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 1073-82. PMID 18039927 DOI: 10.1096/fj.07-9944com  0.52
2008 Yvan-Charvet L, Pagler TA, Wang N, Senokuchi T, Brundert M, Li H, Rinninger F, Tall AR. SR-BI inhibits ABCG1-stimulated net cholesterol efflux from cells to plasma HDL. Journal of Lipid Research. 49: 107-14. PMID 17960026 DOI: 10.1194/jlr.M700200-JLR200  0.52
2007 Tabas I, Seimon T, Arellano J, Li Y, Forcheron F, Cui D, Han S, Liang CP, Tall A, Accili D. The impact of insulin resistance on macrophage death pathways in advanced atherosclerosis. Novartis Foundation Symposium. 286: 99-109; discussion 1. PMID 18269177  0.92
2007 Yvan-Charvet L, Ranalletta M, Wang N, Han S, Terasaka N, Li R, Welch C, Tall AR. Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice. The Journal of Clinical Investigation. 117: 3900-8. PMID 17992262 DOI: 10.1172/JCI33372  0.92
2007 Welch CL, Sun Y, Arey BJ, Lemaitre V, Sharma N, Ishibashi M, Sayers S, Li R, Gorelik A, Pleskac N, Collins-Fletcher K, Yasuda Y, Bromme D, D'Armiento JM, Ogletree ML, ... Tall AR, et al. Spontaneous atherothrombosis and medial degradation in Apoe-/-, Npc1-/- mice. Circulation. 116: 2444-52. PMID 17984379 DOI: 10.1161/CIRCULATIONAHA.107.701276  0.92
2007 Barter PJ, Caulfield M, Eriksson M, Grundy SM, Kastelein JJ, Komajda M, Lopez-Sendon J, Mosca L, Tardif JC, Waters DD, Shear CL, Revkin JH, Buhr KA, Fisher MR, Tall AR, et al. Effects of torcetrapib in patients at high risk for coronary events. The New England Journal of Medicine. 357: 2109-22. PMID 17984165 DOI: 10.1056/NEJMoa0706628  0.92
2007 Terasaka N, Wang N, Yvan-Charvet L, Tall AR. High-density lipoprotein protects macrophages from oxidized low-density lipoprotein-induced apoptosis by promoting efflux of 7-ketocholesterol via ABCG1. Proceedings of the National Academy of Sciences of the United States of America. 104: 15093-8. PMID 17846428 DOI: 10.1073/pnas.0704602104  0.52
2007 Wang X, Collins HL, Ranalletta M, Fuki IV, Billheimer JT, Rothblat GH, Tall AR, Rader DJ. Macrophage ABCA1 and ABCG1, but not SR-BI, promote macrophage reverse cholesterol transport in vivo. The Journal of Clinical Investigation. 117: 2216-24. PMID 17657311 DOI: 10.1172/JCI32057  0.92
2007 Cui D, Thorp E, Li Y, Wang N, Yvan-Charvet L, Tall AR, Tabas I. Pivotal advance: macrophages become resistant to cholesterol-induced death after phagocytosis of apoptotic cells. Journal of Leukocyte Biology. 82: 1040-50. PMID 17576822 DOI: 10.1189/jlb.0307192  0.92
2007 Liang CP, Han S, Senokuchi T, Tall AR. The macrophage at the crossroads of insulin resistance and atherosclerosis. Circulation Research. 100: 1546-55. PMID 17556668 DOI: 10.1161/CIRCRESAHA.107.152165  0.44
2007 Yvan-Charvet L, Matsuura F, Wang N, Bamberger MJ, Nguyen T, Rinninger F, Jiang XC, Shear CL, Tall AR. Inhibition of cholesteryl ester transfer protein by torcetrapib modestly increases macrophage cholesterol efflux to HDL. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 1132-8. PMID 17322101 DOI: 10.1161/ATVBAHA.106.138347  0.52
2007 Tall AR, Yvan-Charvet L, Wang N. The failure of torcetrapib: was it the molecule or the mechanism? Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 257-60. PMID 17229967 DOI: 10.1161/01.ATV.0000256728.60226.77  0.52
2006 Ranalletta M, Wang N, Han S, Yvan-Charvet L, Welch C, Tall AR. Decreased atherosclerosis in low-density lipoprotein receptor knockout mice transplanted with Abcg1-/- bone marrow. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 2308-15. PMID 16917103 DOI: 10.1161/01.ATV.0000242275.92915.43  0.92
2006 Jehle AW, Gardai SJ, Li S, Linsel-Nitschke P, Morimoto K, Janssen WJ, Vandivier RW, Wang N, Greenberg S, Dale BM, Qin C, Henson PM, Tall AR. ATP-binding cassette transporter A7 enhances phagocytosis of apoptotic cells and associated ERK signaling in macrophages. The Journal of Cell Biology. 174: 547-56. PMID 16908670 DOI: 10.1083/jcb.200601030  0.52
2006 Zhou H, Li Z, Hojjati MR, Jang D, Beyer TP, Cao G, Tall AR, Jiang XC. Adipose tissue-specific CETP expression in mice: impact on plasma lipoprotein metabolism. Journal of Lipid Research. 47: 2011-9. PMID 16751623 DOI: 10.1194/jlr.M600153-JLR200  0.92
2006 Matsuura F, Wang N, Chen W, Jiang XC, Tall AR. HDL from CETP-deficient subjects shows enhanced ability to promote cholesterol efflux from macrophages in an apoE- and ABCG1-dependent pathway. The Journal of Clinical Investigation. 116: 1435-42. PMID 16670775 DOI: 10.1172/JCI27602  0.84
2006 Nelson JC, Jiang XC, Tabas I, Tall A, Shea S. Plasma sphingomyelin and subclinical atherosclerosis: findings from the multi-ethnic study of atherosclerosis. American Journal of Epidemiology. 163: 903-12. PMID 16611667 DOI: 10.1093/aje/kwj140  0.92
2006 Han S, Liang CP, DeVries-Seimon T, Ranalletta M, Welch CL, Collins-Fletcher K, Accili D, Tabas I, Tall AR. Macrophage insulin receptor deficiency increases ER stress-induced apoptosis and necrotic core formation in advanced atherosclerotic lesions. Cell Metabolism. 3: 257-66. PMID 16581003 DOI: 10.1016/j.cmet.2006.02.008  0.92
2006 Wang N, Ranalletta M, Matsuura F, Peng F, Tall AR. LXR-induced redistribution of ABCG1 to plasma membrane in macrophages enhances cholesterol mass efflux to HDL. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 1310-6. PMID 16556852 DOI: 10.1161/01.ATV.0000218998.75963.02  0.92
2006 Gerbod-Giannone MC, Li Y, Holleboom A, Han S, Hsu LC, Tabas I, Tall AR. TNFalpha induces ABCA1 through NF-kappaB in macrophages and in phagocytes ingesting apoptotic cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 3112-7. PMID 16492740 DOI: 10.1073/pnas.0510345103  0.92
2006 Li Y, Gerbod-Giannone MC, Seitz H, Cui D, Thorp E, Tall AR, Matsushima GK, Tabas I. Cholesterol-induced apoptotic macrophages elicit an inflammatory response in phagocytes, which is partially attenuated by the Mer receptor. The Journal of Biological Chemistry. 281: 6707-17. PMID 16380374 DOI: 10.1074/jbc.M510579200  0.92
2005 Vikramadithyan RK, Hu Y, Noh HL, Liang CP, Hallam K, Tall AR, Ramasamy R, Goldberg IJ. Human aldose reductase expression accelerates diabetic atherosclerosis in transgenic mice. The Journal of Clinical Investigation. 115: 2434-43. PMID 16127462 DOI: 10.1172/JCI24819  0.4
2005 Chen W, Wang N, Tall AR. A PEST deletion mutant of ABCA1 shows impaired internalization and defective cholesterol efflux from late endosomes. The Journal of Biological Chemistry. 280: 29277-81. PMID 15951431 DOI: 10.1074/jbc.M505566200  0.84
2005 Li Y, Schwabe RF, DeVries-Seimon T, Yao PM, Gerbod-Giannone MC, Tall AR, Davis RJ, Flavell R, Brenner DA, Tabas I. Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-alpha and interleukin-6: model of NF-kappaB- and map kinase-dependent inflammation in advanced atherosclerosis. The Journal of Biological Chemistry. 280: 21763-72. PMID 15826936 DOI: 10.1074/jbc.M501759200  0.92
2005 Desrumaux C, Risold PY, Schroeder H, Deckert V, Masson D, Athias A, Laplanche H, Le Guern N, Blache D, Jiang XC, Tall AR, Desor D, Lagrost L. Phospholipid transfer protein (PLTP) deficiency reduces brain vitamin E content and increases anxiety in mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 296-7. PMID 15576481 DOI: 10.1096/fj.04-2400fje  0.92
2005 Linsel-Nitschke P, Jehle AW, Shan J, Cao G, Bacic D, Lan D, Wang N, Tall AR. Potential role of ABCA7 in cellular lipid efflux to apoA-I. Journal of Lipid Research. 46: 86-92. PMID 15520449 DOI: 10.1194/jlr.M400247-JLR200  0.52
2005 Seidelmann SB, De Luca C, Leibel RL, Breslow JL, Tall AR, Welch CL. Quantitative trait locus mapping of genetic modifiers of metabolic syndrome and atherosclerosis in low-density lipoprotein receptor-deficient mice: identification of a locus for metabolic syndrome and increased atherosclerosis on chromosome 4. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 204-10. PMID 15514201 DOI: 10.1161/01.ATV.0000149146.32385.1b  0.92
2004 Wang N, Lan D, Chen W, Matsuura F, Tall AR. ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins. Proceedings of the National Academy of Sciences of the United States of America. 101: 9774-9. PMID 15210959 DOI: 10.1073/pnas.0403506101  0.84
2004 Liang CP, Han S, Okamoto H, Carnemolla R, Tabas I, Accili D, Tall AR. Increased CD36 protein as a response to defective insulin signaling in macrophages. The Journal of Clinical Investigation. 113: 764-73. PMID 14991075 DOI: 10.1172/JCI19528  0.92
2004 Masson D, Staels B, Gautier T, Desrumaux C, Athias A, Le Guern N, Schneider M, Zak Z, Dumont L, Deckert V, Tall A, Jiang XC, Lagrost L. Cholesteryl ester transfer protein modulates the effect of liver X receptor agonists on cholesterol transport and excretion in the mouse. Journal of Lipid Research. 45: 543-50. PMID 14679166 DOI: 10.1194/jlr.M300432-JLR200  0.92
2003 Costet P, Lalanne F, Gerbod-Giannone MC, Molina JR, Fu X, Lund EG, Gudas LJ, Tall AR. Retinoic acid receptor-mediated induction of ABCA1 in macrophages. Molecular and Cellular Biology. 23: 7756-66. PMID 14560020 DOI: 10.1128/MCB.23.21.7756-7766.2003  0.92
2003 Wang N, Lan D, Gerbod-Giannone M, Linsel-Nitschke P, Jehle AW, Chen W, Martinez LO, Tall AR. ATP-binding cassette transporter A7 (ABCA7) binds apolipoprotein A-I and mediates cellular phospholipid but not cholesterol efflux. The Journal of Biological Chemistry. 278: 42906-12. PMID 12917409 DOI: 10.1074/jbc.M307831200  0.92
2003 Martinez LO, Agerholm-Larsen B, Wang N, Chen W, Tall AR. Phosphorylation of a pest sequence in ABCA1 promotes calpain degradation and is reversed by ApoA-I. The Journal of Biological Chemistry. 278: 37368-74. PMID 12869555 DOI: 10.1074/jbc.M307161200  0.84
2003 Sun Y, Yao J, Kim TW, Tall AR. Expression of liver X receptor target genes decreases cellular amyloid beta peptide secretion. The Journal of Biological Chemistry. 278: 27688-94. PMID 12754201 DOI: 10.1074/jbc.M300760200  0.48
2003 Wang N, Tall AR. Regulation and mechanisms of ATP-binding cassette transporter A1-mediated cellular cholesterol efflux. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 1178-84. PMID 12738681 DOI: 10.1161/01.ATV.0000075912.83860.26  0.52
2003 Wang N, Chen W, Linsel-Nitschke P, Martinez LO, Agerholm-Larsen B, Silver DL, Tall AR. A PEST sequence in ABCA1 regulates degradation by calpain protease and stabilization of ABCA1 by apoA-I. The Journal of Clinical Investigation. 111: 99-107. PMID 12511593 DOI: 10.1172/JCI16808  0.92
2003 Sun Y, Hao M, Luo Y, Liang CP, Silver DL, Cheng C, Maxfield FR, Tall AR. Stearoyl-CoA desaturase inhibits ATP-binding cassette transporter A1-mediated cholesterol efflux and modulates membrane domain structure. The Journal of Biological Chemistry. 278: 5813-20. PMID 12482877 DOI: 10.1074/jbc.M208687200  0.92
2002 Tall AR, Costet P, Wang N. Regulation and mechanisms of macrophage cholesterol efflux. The Journal of Clinical Investigation. 110: 899-904. PMID 12370265 DOI: 10.1172/JCI16391  0.52
2002 Jiang XC, Tall AR, Qin S, Lin M, Schneider M, Lalanne F, Deckert V, Desrumaux C, Athias A, Witztum JL, Lagrost L. Phospholipid transfer protein deficiency protects circulating lipoproteins from oxidation due to the enhanced accumulation of vitamin E. The Journal of Biological Chemistry. 277: 31850-6. PMID 12105225 DOI: 10.1074/jbc.M205077200  0.92
2002 Gautier T, Masson D, Jong MC, Duverneuil L, Le Guern N, Deckert V, Pais de Barros JP, Dumont L, Bataille A, Zak Z, Jiang XC, Tall AR, Havekes LM, Lagrost L. Apolipoprotein CI deficiency markedly augments plasma lipoprotein changes mediated by human cholesteryl ester transfer protein (CETP) in CETP transgenic/ApoCI-knocked out mice. The Journal of Biological Chemistry. 277: 31354-63. PMID 12070157 DOI: 10.1074/jbc.M203151200  0.36
2002 Kako Y, Massé M, Huang LS, Tall AR, Goldberg IJ. Lipoprotein lipase deficiency and CETP in streptozotocin-treated apoB-expressing mice. Journal of Lipid Research. 43: 872-7. PMID 12032161  0.4
2002 Weinberg RB, Anderson RA, Cook VR, Emmanuel F, Denèfle P, Tall AR, Steinmetz A. Interfacial exclusion pressure determines the ability of apolipoprotein A-IV truncation mutants to activate cholesterol ester transfer protein. The Journal of Biological Chemistry. 277: 21549-53. PMID 11940599 DOI: 10.1074/jbc.M202197200  0.92
2001 Leventhal AR, Chen W, Tall AR, Tabas I. Acid sphingomyelinase-deficient macrophages have defective cholesterol trafficking and efflux. The Journal of Biological Chemistry. 276: 44976-83. PMID 11579092 DOI: 10.1074/jbc.M106455200  0.92
2001 Chen W, Sun Y, Welch C, Gorelik A, Leventhal AR, Tabas I, Tall AR. Preferential ATP-binding cassette transporter A1-mediated cholesterol efflux from late endosomes/lysosomes. The Journal of Biological Chemistry. 276: 43564-9. PMID 11559713 DOI: 10.1074/jbc.M107938200  0.92
1998 Jeong Ts, Schissel SL, Tabas I, Pownall HJ, Tall AR, Jiang X. Increased sphingomyelin content of plasma lipoproteins in apolipoprotein E knockout mice reflects combined production and catabolic defects and enhances reactivity with mammalian sphingomyelinase. The Journal of Clinical Investigation. 101: 905-12. PMID 9466986 DOI: 10.1172/JCI870  0.92
1996 Wang N, Tabas I, Winchester R, Ravalli S, Rabbani LE, Tall A. Interleukin 8 is induced by cholesterol loading of macrophages and expressed by macrophage foam cells in human atheroma. The Journal of Biological Chemistry. 271: 8837-42. PMID 8621523 DOI: 10.1074/jbc.271.15.8837  0.92
1987 Tabas I, Boykow GC, Tall AR. Foam cell-forming J774 macrophages have markedly elevated acyl coenzyme A:cholesterol acyl transferase activity compared with mouse peritoneal macrophages in the presence of low density lipoprotein (LDL) despite similar LDL receptor activity. The Journal of Clinical Investigation. 79: 418-26. PMID 3805276 DOI: 10.1172/JCI112828  0.92
1987 Tall A, Granot E, Brocia R, Tabas I, Hesler C, Williams K, Denke M. Accelerated transfer of cholesteryl esters in dyslipidemic plasma. Role of cholesteryl ester transfer protein. The Journal of Clinical Investigation. 79: 1217-25. PMID 3558822 DOI: 10.1172/JCI112940  0.92
1987 Granot E, Tabas I, Tall AR. Human plasma cholesteryl ester transfer protein enhances the transfer of cholesteryl ester from high density lipoproteins into cultured HepG2 cells. The Journal of Biological Chemistry. 262: 3482-7. PMID 3029115  0.92
1986 Tabas I, Weiland DA, Tall AR. Inhibition of acyl coenzyme A:cholesterol acyl transferase in J774 macrophages enhances down-regulation of the low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl-coenzyme A reductase and prevents low density lipoprotein-induced cholesterol accumulation. The Journal of Biological Chemistry. 261: 3147-55. PMID 3949765  0.92
1986 Tall AR, Tabas I, Williams KJ. Lipoprotein-liposome interactions. Methods in Enzymology. 128: 647-57. PMID 3724528  0.92
1986 Williams KJ, Tall AR, Tabas I, Blum C. Recognition of vesicular lipoproteins by the apolipoprotein B,E receptor of cultured fibroblasts. Journal of Lipid Research. 27: 892-900. PMID 3021887  0.92
1985 Tabas I, Weiland DA, Tall AR. Unmodified low density lipoprotein causes cholesteryl ester accumulation in J774 macrophages. Proceedings of the National Academy of Sciences of the United States of America. 82: 416-20. PMID 3855559  0.92
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