Randy Strong - Publications

Affiliations: 
The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States 
Area:
Pharmacology, Pharmaceutical Chemistry

55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Soto-Piña AE, Franklin C, Rani CSS, Fernandez E, Cardoso-Peña E, Benítez-Arciniega AD, Gottlieb H, Hinojosa-Laborde C, Strong R. Dexamethasone Causes Hypertension in Rats Even Under Chemical Blockade of Peripheral Sympathetic Nerves. Frontiers in Neuroscience. 13: 1305. PMID 31866814 DOI: 10.3389/Fnins.2019.01305  0.32
2019 Smith BJ, Miller RA, Ericsson AC, Harrison DC, Strong R, Schmidt TM. Changes in the gut microbiome and fermentation products concurrent with enhanced longevity in acarbose-treated mice. Bmc Microbiology. 19: 130. PMID 31195972 DOI: 10.1186/S12866-019-1494-7  0.334
2019 Miller RA, Harrison DE, Astle CM, Bogue MA, Brind J, Fernandez E, Flurkey K, Javors M, Ladiges W, Leeuwenburgh C, Macchiarini F, Nelson J, Ryazanov AG, Snyder J, Stearns TM, ... ... Strong R, et al. Glycine supplementation extends lifespan of male and female mice. Aging Cell. e12953. PMID 30916479 DOI: 10.1111/Acel.12953  0.341
2017 Bai X, Wey MC, Martinez PA, Shi C, Fernandez E, Strong R. Neurochemical and motor changes in mice with combined mutations linked to Parkinson's disease. Pathobiology of Aging & Age Related Diseases. 7: 1267855. PMID 28326165 DOI: 10.1080/20010001.2017.1267855  0.776
2016 Soto-Pina AE, Franklin C, Rani CS, Gottlieb H, Hinojosa-Laborde C, Strong R. A novel model of dexamethasone-induced hypertension: use in investigating the role of tyrosine hydroxylase. The Journal of Pharmacology and Experimental Therapeutics. PMID 27405316 DOI: 10.1124/Jpet.116.234005  0.365
2016 Strong R, Miller RA, Antebi A, Astle CM, Bogue M, Denzel MS, Fernandez E, Flurkey K, Hamilton KL, Lamming DW, Javors MA, de Magalhães JP, Marinez PA, McCord JM, Miller BF, et al. Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer. Aging Cell. PMID 27312235 DOI: 10.1111/Acel.12496  0.303
2015 Bai X, Wey MC, Fernandez E, Hart MJ, Gelfond J, Bokov AF, Rani S, Strong R. Rapamycin improves motor function, reduces 4-hydroxynonenal adducted protein in brain, and attenuates synaptic injury in a mouse model of synucleinopathy. Pathobiology of Aging & Age Related Diseases. 5: 28743. PMID 26306821  0.766
2014 Rodriguez KA, Dodds SG, Strong R, Galvan V, Sharp ZD, Buffenstein R. Divergent tissue and sex effects of rapamycin on the proteasome-chaperone network of old mice. Frontiers in Molecular Neuroscience. 7: 83. PMID 25414638 DOI: 10.3389/Fnmol.2014.00083  0.316
2014 Miller RA, Harrison DE, Astle CM, Fernandez E, Flurkey K, Han M, Javors MA, Li X, Nadon NL, Nelson JF, Pletcher S, Salmon AB, Sharp ZD, Van Roekel S, Winkleman L, ... Strong R, et al. Rapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction. Aging Cell. 13: 468-77. PMID 24341993 DOI: 10.1111/Acel.12194  0.348
2014 Hasty P, Livi CB, Dodds SG, Jones D, Strong R, Javors M, Fischer KE, Sloane L, Murthy K, Hubbard G, Sun L, Hurez V, Curiel TJ, Sharp ZD. eRapa restores a normal life span in a FAP mouse model. Cancer Prevention Research (Philadelphia, Pa.). 7: 169-78. PMID 24282255 DOI: 10.1158/1940-6207.Capr-13-0299  0.353
2013 Li X, Redus L, Chen C, Martinez PA, Strong R, Li S, O'Connor JC. Cognitive dysfunction precedes the onset of motor symptoms in the MitoPark mouse model of Parkinson's disease. Plos One. 8: e71341. PMID 23977020 DOI: 10.1371/Journal.Pone.0071341  0.364
2013 Goldstein DS, Sullivan P, Holmes C, Miller GW, Alter S, Strong R, Mash DC, Kopin IJ, Sharabi Y. Determinants of buildup of the toxic dopamine metabolite DOPAL in Parkinson's disease. Journal of Neurochemistry. 126: 591-603. PMID 23786406 DOI: 10.1111/Jnc.12345  0.35
2013 Flynn JM, O'Leary MN, Zambataro CA, Academia EC, Presley MP, Garrett BJ, Zykovich A, Mooney SD, Strong R, Rosen CJ, Kapahi P, Nelson MD, Kennedy BK, Melov S. Late-life rapamycin treatment reverses age-related heart dysfunction. Aging Cell. 12: 851-62. PMID 23734717 DOI: 10.1111/Acel.12109  0.327
2013 Sheela Rani CS, Soto-Pina A, Iacovitti L, Strong R. Evolutionary conservation of an atypical glucocorticoid-responsive element in the human tyrosine hydroxylase gene. Journal of Neurochemistry. 126: 19-28. PMID 23647419 DOI: 10.1111/Jnc.12294  0.402
2013 Strong R, Miller RA, Astle CM, Baur JA, de Cabo R, Fernandez E, Guo W, Javors M, Kirkland JL, Nelson JF, Sinclair DA, Teter B, Williams D, Zaveri N, Nadon NL, et al. Evaluation of resveratrol, green tea extract, curcumin, oxaloacetic acid, and medium-chain triglyceride oil on life span of genetically heterogeneous mice. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 68: 6-16. PMID 22451473 DOI: 10.1093/Gerona/Gls070  0.303
2012 Ramos FJ, Chen SC, Garelick MG, Dai DF, Liao CY, Schreiber KH, MacKay VL, An EH, Strong R, Ladiges WC, Rabinovitch PS, Kaeberlein M, Kennedy BK. Rapamycin reverses elevated mTORC1 signaling in lamin A/C-deficient mice, rescues cardiac and skeletal muscle function, and extends survival. Science Translational Medicine. 4: 144ra103. PMID 22837538 DOI: 10.1126/Scitranslmed.3003802  0.307
2012 Halloran J, Hussong SA, Burbank R, Podlutskaya N, Fischer KE, Sloane LB, Austad SN, Strong R, Richardson A, Hart MJ, Galvan V. Chronic inhibition of mammalian target of rapamycin by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice. Neuroscience. 223: 102-13. PMID 22750207 DOI: 10.1016/J.Neuroscience.2012.06.054  0.354
2012 Wilkinson JE, Burmeister L, Brooks SV, Chan CC, Friedline S, Harrison DE, Hejtmancik JF, Nadon N, Strong R, Wood LK, Woodward MA, Miller RA. Rapamycin slows aging in mice. Aging Cell. 11: 675-82. PMID 22587563 DOI: 10.1111/J.1474-9726.2012.00832.X  0.351
2012 Wey MC, Fernandez E, Martinez PA, Sullivan P, Goldstein DS, Strong R. Neurodegeneration and motor dysfunction in mice lacking cytosolic and mitochondrial aldehyde dehydrogenases: implications for Parkinson's disease. Plos One. 7: e31522. PMID 22384032 DOI: 10.1371/Journal.Pone.0031522  0.762
2012 Majumder S, Caccamo A, Medina DX, Benavides AD, Javors MA, Kraig E, Strong R, Richardson A, Oddo S. Lifelong rapamycin administration ameliorates age-dependent cognitive deficits by reducing IL-1β and enhancing NMDA signaling. Aging Cell. 11: 326-35. PMID 22212527 DOI: 10.1111/J.1474-9726.2011.00791.X  0.314
2011 Green MK, Rani CS, Joshi A, Soto-Piña AE, Martinez PA, Frazer A, Strong R, Morilak DA. Prenatal stress induces long term stress vulnerability, compromising stress response systems in the brain and impairing extinction of conditioned fear after adult stress. Neuroscience. 192: 438-51. PMID 21723377 DOI: 10.1016/J.Neuroscience.2011.06.041  0.305
2011 Miller RA, Harrison DE, Astle CM, Baur JA, Boyd AR, De Cabo R, Fernandez E, Flurkey K, Javors MA, Nelson JF, Orihuela CJ, Pletcher S, Sharp ZD, Sinclair D, Starnes JW, ... ... Strong R, et al. Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice Journals of Gerontology - Series a Biological Sciences and Medical Sciences. 66: 191-201. PMID 20974732 DOI: 10.1093/Gerona/Glq178  0.334
2011 Bai X, Wey MC, Martinez A, Bergmen P, Martinez V, Fernandez E, Strong R. Simultaneous Deletion of Endogenous Gpx1 and Aldh1a1 Genes Results in Motor Deficits in Young Adult Mice Free Radical Biology and Medicine. 51: S68. DOI: 10.1016/J.Freeradbiomed.2011.10.176  0.756
2010 Khodr CE, Clark S, Bokov AF, Richardson A, Strong R, Hurley DL, Phelps CJ. Early postnatal administration of growth hormone increases tuberoinfundibular dopaminergic neuron numbers in Ames dwarf mice. Endocrinology. 151: 3277-85. PMID 20463054 DOI: 10.1210/En.2009-1482  0.315
2010 Spilman P, Podlutskaya N, Hart MJ, Debnath J, Gorostiza O, Bredesen D, Richardson A, Strong R, Galvan V. Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-β levels in a mouse model of alzheimer's disease Plos One. 5. PMID 20376313 DOI: 10.1371/Journal.Pone.0009979  0.309
2009 Harrison DE, Strong R, Sharp ZD, Nelson JF, Astle CM, Flurkey K, Nadon NL, Wilkinson JE, Frenkel K, Carter CS, Pahor M, Javors MA, Fernandez E, Miller RA. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature. 460: 392-5. PMID 19587680 DOI: 10.1038/Nature08221  0.35
2009 Price DA, Martinez AA, Seillier A, Koek W, Acosta Y, Fernandez E, Strong R, Lutz B, Marsicano G, Roberts JL, Giuffrida A. WIN55,212-2, a cannabinoid receptor agonist, protects against nigrostriatal cell loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease. The European Journal of Neuroscience. 29: 2177-86. PMID 19490092 DOI: 10.1111/J.1460-9568.2009.06764.X  0.366
2009 Rani CS, Elango N, Wang SS, Kobayashi K, Strong R. Identification of an activator protein-1-like sequence as the glucocorticoid response element in the rat tyrosine hydroxylase gene. Molecular Pharmacology. 75: 589-98. PMID 19060113 DOI: 10.1124/Mol.108.051219  0.42
2008 Strong R, Miller RA, Astle CM, Floyd RA, Flurkey K, Hensley KL, Javors MA, Leeuwenburgh C, Nelson JF, Ongini E, Nadon NL, Warner HR, Harrison DE. Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice. Aging Cell. 7: 641-50. PMID 18631321 DOI: 10.1111/J.1474-9726.2008.00414.X  0.328
2007 McCarter R, Mejia W, Ikeno Y, Monnier V, Kewitt K, Gibbs M, McMahan A, Strong R. Plasma glucose and the action of calorie restriction on aging. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 62: 1059-70. PMID 17921417 DOI: 10.1093/Gerona/62.10.1059  0.325
2006 Fernandez E, Koek W, Ran Q, Gerhardt GA, France CP, Strong R. Monoamine metabolism and behavioral responses to ethanol in mitochondrial aldehyde dehydrogenase knockout mice. Alcoholism, Clinical and Experimental Research. 30: 1650-8. PMID 17010132 DOI: 10.1111/J.1530-0277.2006.00200.X  0.327
2006 Muller FL, Song W, Liu Y, Chaudhuri A, Pieke-Dahl S, Strong R, Huang TT, Epstein CJ, Roberts LJ, Csete M, Faulkner JA, Van Remmen H. Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophy. Free Radical Biology & Medicine. 40: 1993-2004. PMID 16716900 DOI: 10.1016/J.Freeradbiomed.2006.01.036  0.301
2004 Van Remmen H, Qi W, Sabia M, Freeman G, Estlack L, Yang H, Mao Guo Z, Huang TT, Strong R, Lee S, Epstein CJ, Richardson A. Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress. Free Radical Biology & Medicine. 36: 1625-34. PMID 15182862 DOI: 10.1016/J.Freeradbiomed.2004.03.016  0.338
2003 Liang H, Masoro EJ, Nelson JF, Strong R, McMahan CA, Richardson A. Genetic mouse models of extended lifespan. Experimental Gerontology. 38: 1353-64. PMID 14698816 DOI: 10.1016/J.Exger.2003.10.019  0.346
2003 Van Remmen H, Ikeno Y, Hamilton M, Pahlavani M, Wolf N, Thorpe SR, Alderson NL, Baynes JW, Epstein CJ, Huang TT, Nelson J, Strong R, Richardson A. Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging. Physiological Genomics. 16: 29-37. PMID 14679299 DOI: 10.1152/Physiolgenomics.00122.2003  0.358
2003 Strong R, Reddy V, Morley JE. Cholinergic deficits in the septal-hippocampal pathway of the SAM-P/8 senescence accelerated mouse. Brain Research. 966: 150-6. PMID 12646318 DOI: 10.1016/S0006-8993(02)04192-6  0.322
2002 Corbitt J, Hagerty T, Fernandez E, Morgan WW, Strong R. Transcriptional and post-transcriptional regulation of tyrosine hydroxylase messenger RNA in PC12 cells during persistent stimulation by VIP and PACAP38: differential regulation by protein kinase A and protein kinase C-dependent pathways. Neuropeptides. 36: 34-45. PMID 12147212 DOI: 10.1054/Npep.2002.0885  0.698
2002 Dong LQ, Ramos FJ, Wick MJ, Lim MA, Guo Z, Strong R, Richardson A, Liu F. Cloning and characterization of a testis and brain-specific isoform of mouse 3'-phosphoinositide-dependent protein kinase-1, mPDK-1 beta. Biochemical and Biophysical Research Communications. 294: 136-44. PMID 12054753 DOI: 10.1016/S0006-291X(02)00449-7  0.341
2002 Corbitt J, Vivekananda J, Wang SS, Strong R. Transcriptional and posttranscriptional control of tyrosine hydroxylase gene expression during persistent stimulation of pituitary adenylate cyclase-activating polypeptide receptors on PC12 cells: regulation by protein kinase A-dependent and protein kinase A-independent pathways. Journal of Neurochemistry. 71: 478-486. PMID 9681437 DOI: 10.1046/J.1471-4159.1998.71020478.X  0.789
2001 Hagerty T, Fernandez E, Lynch K, Wang SS, Morgan WW, Strong R. Interaction of a glucocorticoid-responsive element with regulatory sequences in the promoter region of the mouse tyrosine hydroxylase gene. Journal of Neurochemistry. 78: 1379-88. PMID 11579146 DOI: 10.1046/J.1471-4159.2001.00521.X  0.764
2001 Foster D, Strong R, Morgan WW. A tetracycline-repressible transactivator approach suggests a shorter half-life for tyrosine hydroxylase mRNA. Brain Research. Brain Research Protocols. 7: 137-46. PMID 11356380 DOI: 10.1016/S1385-299X(01)00056-3  0.45
2001 Hagerty T, Morgan WW, Elango N, Strong R. Identification of a glucocorticoid-responsive element in the promoter region of the mouse tyrosine hydroxylase gene. Journal of Neurochemistry. 76: 825-34. PMID 11158254 DOI: 10.1046/J.1471-4159.2001.00072.X  0.752
2000 Sands SA, Strong R, Corbitt J, Morilak DA. Effects of acute restraint stress on tyrosine hydroxylase mRNA expression in locus coeruleus of Wistar and Wistar-Kyoto rats Molecular Brain Research. 75: 1-7. PMID 10648882 DOI: 10.1016/S0169-328X(99)00255-7  0.744
1995 Mattammal MB, Haring JH, Chung HD, Raghu G, Strong R. An endogenous dopaminergic neurotoxin: implication for Parkinson's disease. Neurodegeneration. 4: 271-281. PMID 8581559 DOI: 10.1016/1055-8330(95)90016-0  0.321
1993 Wessels-Reiker M, Basiboina R, Howlett AC, Strong R. Vasoactive intestinal polypeptide-related peptides modulate tyrosine hydroxylase gene expression in PC12 cells through multiple adenylate cyclase-coupled receptors. Journal of Neurochemistry. 60: 1018-29. PMID 8094740 DOI: 10.1111/J.1471-4159.1993.Tb03250.X  0.44
1993 Heydari AR, Wu B, Takahashi R, Strong R, Richardson A. Expression of heat shock protein 70 is altered by age and diet at the level of transcription. Molecular and Cellular Biology. 13: 2909-18. PMID 7682654 DOI: 10.1128/mcb.13.5.2909-2918.1993  0.303
1992 Tümer N, Hale C, Lawler J, Strong R. Modulation of tyrosine hydroxylase gene expression in the rat adrenal gland by exercise: effects of age. Molecular Brain Research. 14: 51-56. PMID 1353855 DOI: 10.1016/0169-328X(92)90009-Z  0.358
1990 Strong R, Hale C, Moore MA, Wessels-Reiker M, Armbrecht HJ, Richardson A. GABA receptor modulation of tyrosine hydroxylase gene expression in the rat adrenal gland. Neuroscience Letters. 117: 175-180. PMID 1981253 DOI: 10.1016/0304-3940(90)90140-5  0.359
1990 Strong R, Moore MA, Hale C, Wessels-Reiker M, Armbrecht HJ, Richardson A. Modulation of tyrosine hydroxylase gene expression in the rat adrenal gland by age and reserpine Brain Research. 525: 126-132. PMID 1978789 DOI: 10.1016/0006-8993(90)91327-D  0.472
1987 Strong R. Regionally selective manifestations of neostriatal aging Annals of the New York Academy of Sciences. 515: 161-177. PMID 2966603 DOI: 10.1111/J.1749-6632.1988.Tb32980.X  0.317
1987 Sun GY, Huang H-, Lee D-, Chung-Wang Y-, Wood WG, Strong R, Sun AY. Chronic ethanol effect on the acidic phospholipids of synaptosomes isolated from cerebral cortex of C57BL/6NNIA mice--a comparison with age. Alcohol and Alcoholism. 22: 367-373. DOI: 10.1093/Oxfordjournals.Alcalc.A044725  0.309
1986 Strong R, Rehwaldt C, Wood WG. Intra-regional variations in the effect of aging on high affinity choline uptake, choline acetyltransferase and muscarinic cholinergic receptors in rat neostriatum. Experimental Gerontology. 21: 177-186. PMID 3803469 DOI: 10.1016/0531-5565(86)90071-9  0.315
1984 Strong R, Waymire JC, Samorajski T, Gottesfeld Z. Regional analysis of neostriatal cholinergic and dopaminergic receptor binding and tyrosine hydroxylase activity as a function of aging. Neurochemical Research. 9: 1641-52. PMID 6151626 DOI: 10.1007/Bf00964597  0.363
1980 Strong R, Hicks P, Hsu L, Bartus RT, Enna SJ. Age-related alterations in the rodent brain cholinergic system and behavior. Neurobiology of Aging. 1: 59-63. PMID 7266736 DOI: 10.1016/0197-4580(80)90025-1  0.336
1980 Hicks P, Strong R, Schoolar JC, Samorajski T. Aging alters amphetamine-induced stereotyped gnawing and neostriatal elimination of amphetamine in mice. Life Sciences. 27: 715-22. PMID 7191038 DOI: 10.1016/0024-3205(80)90324-0  0.365
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