Year |
Citation |
Score |
2023 |
Baxter RM, Wang CS, Garcia-Perez JE, Kong DS, Coleman BM, Larchenko V, Schuyler RP, Jackson C, Ghosh T, Rudra P, Paul D, Claassen M, Rochford R, Cambier JC, Ghosh D, et al. Expansion of extrafollicular B and T cell subsets in childhood-onset systemic lupus erythematosus. Frontiers in Immunology. 14: 1208282. PMID 37965329 DOI: 10.3389/fimmu.2023.1208282 |
0.325 |
|
2023 |
Wemlinger SM, Cambier JC. Therapeutic tactics for targeting B lymphocytes in autoimmunity and cancer. European Journal of Immunology. e2249947. PMID 37816494 DOI: 10.1002/eji.202249947 |
0.351 |
|
2023 |
Palmer WH, Leaton LA, Campos Codo A, Crute B, Roest J, Zhu S, Petersen J, Tobin RP, Hume PS, Stone M, van Bokhoven A, Gerich ME, McCarter MD, Zhu Y, Janssen WJ, ... ... Cambier J, et al. Polymorphic KIR3DL3 expression modulates tissue-resident and innate-like T cells. Science Immunology. 8: eade5343. PMID 37390222 DOI: 10.1126/sciimmunol.ade5343 |
0.338 |
|
2022 |
Banach M, Harley ITW, Getahun A, Cambier JC. Comparative analysis of the repertoire of insulin-reactive B cells in type 1 diabetes-prone and resistant mice. Frontiers in Immunology. 13: 961209. PMID 36275764 DOI: 10.3389/fimmu.2022.961209 |
0.345 |
|
2022 |
Wemlinger SM, Parker Harp CR, Yu B, Hardy IR, Seefeldt M, Matsuda J, Mingueneau M, Spilker KA, Cameron TO, Larrick JW, Getahun A, Cambier JC. Preclinical Analysis of Candidate Anti-Human CD79 Therapeutic Antibodies Using a Humanized CD79 Mouse Model. Journal of Immunology (Baltimore, Md. : 1950). 208: 1566-1584. PMID 35321883 DOI: 10.4049/jimmunol.2101056 |
0.795 |
|
2021 |
Stensland ZC, Cambier JC, Smith MJ. Therapeutic Targeting of Autoreactive B Cells: Why, How, and When? Biomedicines. 9. PMID 33467130 DOI: 10.3390/biomedicines9010083 |
0.362 |
|
2020 |
Crute BW, Sheraden R, Ott VL, Harley ITW, Getahun A, Cambier JC. Inhibitory Receptor Trap: A Platform for Discovery of Inhibitory Receptors That Utilize Inositol Lipid and Phosphotyrosine Phosphatase Effectors. Frontiers in Immunology. 11: 592329. PMID 33193438 DOI: 10.3389/fimmu.2020.592329 |
0.369 |
|
2020 |
Smith MJ, Cambier JC, Gottlieb PA. Endotypes in T1D: B lymphocytes and early onset. Current Opinion in Endocrinology, Diabetes, and Obesity. 27: 225-230. PMID 32618634 DOI: 10.1097/Med.0000000000000547 |
0.435 |
|
2019 |
Atif SM, Mack DG, McKee AS, Rangel-Moreno J, Martin AK, Getahun A, Maier LA, Cambier JC, Tuder R, Fontenot AP. Protective role of B cells in sterile particulate-induced lung injury. Jci Insight. 5. PMID 31094704 DOI: 10.1172/Jci.Insight.125494 |
0.436 |
|
2019 |
Franks SE, Getahun A, Cambier JC. A Precision B Cell-Targeted Therapeutic Approach to Autoimmunity Caused by Phosphatidylinositol 3-Kinase Pathway Dysregulation. Journal of Immunology (Baltimore, Md. : 1950). PMID 31076529 DOI: 10.4049/Jimmunol.1801394 |
0.463 |
|
2019 |
Getahun A, Cambier JC. Non-Antibody-Secreting Functions of B Cells and Their Contribution to Autoimmune Disease. Annual Review of Cell and Developmental Biology. PMID 30883216 DOI: 10.1146/Annurev-Cellbio-100617-062518 |
0.447 |
|
2019 |
Smith MJ, Ford BR, Rihanek M, Coleman BM, Getahun A, Sarapura VD, Gottlieb PA, Cambier JC. Elevated PTEN expression maintains anergy in human B cells and reveals unexpectedly high repertoire autoreactivity. Jci Insight. 4. PMID 30728334 DOI: 10.1172/Jci.Insight.123384 |
0.482 |
|
2019 |
Leon MA, Wemlinger SM, Larson NR, Ruffalo JK, Middaugh CR, Cambier JC, Berkland C. Synthesis and Characterization of Multivalent Protein based Soluble Antigen Arrays for Juvenile Diabetes. Molecular Pharmaceutics. PMID 30681867 DOI: 10.1021/Acs.Molpharmaceut.8B01250 |
0.403 |
|
2018 |
Benhamou D, Labi V, Getahun A, Benchetrit E, Dowery R, Rajewsky K, Cambier JC, Melamed D. The c-Myc/miR17-92/PTEN Axis Tunes PI3K Activity to Control Expression of Recombination Activating Genes in Early B Cell Development. Frontiers in Immunology. 9: 2715. PMID 30524445 DOI: 10.3389/Fimmu.2018.02715 |
0.422 |
|
2018 |
Walker MM, Crute BW, Cambier JC, Getahun A. B Cell-Intrinsic STING Signaling Triggers Cell Activation, Synergizes with B Cell Receptor Signals, and Promotes Antibody Responses. Journal of Immunology (Baltimore, Md. : 1950). PMID 30282750 DOI: 10.4049/Jimmunol.1701405 |
0.529 |
|
2018 |
Smith MJ, Hinman RM, Getahun A, Kim S, Packard TA, Cambier JC. Silencing of high-affinity insulin-reactive B lymphocytes by anergy and impact of the NOD genetic background in mice. Diabetologia. PMID 30255377 DOI: 10.1007/S00125-018-4730-Z |
0.331 |
|
2018 |
Franks SE, Cambier JC. Putting on the Brakes: Regulatory Kinases and Phosphatases Maintaining B Cell Anergy. Frontiers in Immunology. 9: 665. PMID 29681901 DOI: 10.3389/Fimmu.2018.00665 |
0.519 |
|
2018 |
Smith MJ, Rihanek M, Wasserfall C, Mathews CE, Atkinson MA, Gottlieb PA, Cambier JC. Loss of B Cell Anergy in Type 1 Diabetes is Associated with High Risk HLA and non-HLA Disease Susceptibility Alleles. Diabetes. PMID 29343548 DOI: 10.2337/Db17-0937 |
0.365 |
|
2017 |
Ruiz-Moreno JS, Hamann L, Jin L, Sander LE, Puzianowska-Kuznicka M, Cambier J, Witzenrath M, Schumann RR, Suttorp N, Opitz B. The cGAS/STING pathway detects Streptococcus pneumoniae but appears dispensable for anti-pneumococcal defense in mice and humans. Infection and Immunity. PMID 29263110 DOI: 10.1128/Iai.00849-17 |
0.342 |
|
2017 |
Smith MJ, Rihanek M, Coleman BM, Gottlieb PA, Sarapura VD, Cambier JC. Activation of thyroid antigen-reactive B cells in recent onset autoimmune thyroid disease patients. Journal of Autoimmunity. PMID 29233566 DOI: 10.1016/J.Jaut.2017.12.001 |
0.374 |
|
2017 |
Smith MJ, Simmons KM, Cambier JC. B cells in type 1 diabetes mellitus and diabetic kidney disease. Nature Reviews. Nephrology. 13: 712-720. PMID 29038537 DOI: 10.1038/Nrneph.2017.138 |
0.408 |
|
2017 |
Getahun A, Wemlinger SM, Rudra P, Santiago ML, van Dyk LF, Cambier JC. Impaired B cell function during viral infections due to PTEN-mediated inhibition of the PI3K pathway. The Journal of Experimental Medicine. PMID 28341640 DOI: 10.1084/Jem.20160972 |
0.422 |
|
2017 |
Smith MJ, Packard TA, O'Neill SK, Hinman RM, Rihanek M, Gottlieb PA, Cambier JC. Detection and Enrichment of Rare Antigen-specific B Cells for Analysis of Phenotype and Function. Journal of Visualized Experiments : Jove. PMID 28287549 DOI: 10.3791/55382 |
0.47 |
|
2016 |
Seay HR, Yusko E, Rothweiler SJ, Zhang L, Posgai AL, Campbell-Thompson M, Vignali M, Emerson RO, Kaddis JS, Ko D, Nakayama M, Smith MJ, Cambier JC, Pugliese A, Atkinson MA, et al. Tissue distribution and clonal diversity of the T and B cell repertoire in type 1 diabetes. Jci Insight. 1: e88242. PMID 27942583 DOI: 10.1172/Jci.Insight.88242 |
0.443 |
|
2016 |
Packard TA, Smith MJ, Conrad FJ, Johnson SA, Getahun A, Lindsay RS, Hinman RM, Friedman RS, Thomas JW, Cambier JC. B Cell Receptor Affinity for Insulin Dictates Autoantigen Acquisition and B Cell Functionality in Autoimmune Diabetes. Journal of Clinical Medicine. 5. PMID 27834793 DOI: 10.3390/Jcm5110098 |
0.436 |
|
2016 |
Franks SE, Getahun A, Hogarth PM, Cambier JC. Targeting B cells in treatment of autoimmunity. Current Opinion in Immunology. 43: 39-45. PMID 27718447 DOI: 10.1016/J.Coi.2016.09.003 |
0.479 |
|
2016 |
Getahun A, Beavers NA, Larson SR, Shlomchik MJ, Cambier JC. Continuous inhibitory signaling by both SHP-1 and SHIP-1 pathways is required to maintain unresponsiveness of anergic B cells. The Journal of Experimental Medicine. 213: 751-69. PMID 27114609 DOI: 10.1084/Jem.20150537 |
0.507 |
|
2015 |
Huang Y, Getahun A, Heiser RA, Detanico TO, Aviszus K, Kirchenbaum GA, Casper TL, Huang C, Aydintug MK, Carding SR, Ikuta K, Huang H, Wysocki LJ, Cambier JC, O'Brien RL, et al. γδ T Cells Shape Preimmune Peripheral B Cell Populations. Journal of Immunology (Baltimore, Md. : 1950). PMID 26582947 DOI: 10.4049/Jimmunol.1501064 |
0.44 |
|
2015 |
Chen Z, Getahun A, Chen X, Dollin Y, Cambier JC, Wang JH. Imbalanced PTEN and PI3K Signaling Impairs Class Switch Recombination. Journal of Immunology (Baltimore, Md. : 1950). PMID 26500350 DOI: 10.4049/Jimmunol.1501375 |
0.484 |
|
2015 |
Getahun A, Cambier JC. Of ITIMs, ITAMs, and ITAMis: revisiting immunoglobulin Fc receptor signaling. Immunological Reviews. 268: 66-73. PMID 26497513 DOI: 10.1111/Imr.12336 |
0.467 |
|
2015 |
Akerlund J, Getahun A, Cambier JC. B cell expression of the SH2-containing inositol 5-phosphatase (SHIP-1) is required to establish anergy to high affinity, proteinacious autoantigens. Journal of Autoimmunity. 62: 45-54. PMID 26152931 DOI: 10.1016/J.Jaut.2015.06.007 |
0.529 |
|
2015 |
Huang Y, Heiser RA, Detanico TO, Getahun A, Kirchenbaum GA, Casper TL, Aydintug MK, Carding SR, Ikuta K, Huang H, Cambier JC, Wysocki LJ, O'Brien RL, Born WK. γδ T cells affect IL-4 production and B-cell tolerance. Proceedings of the National Academy of Sciences of the United States of America. 112: E39-48. PMID 25535377 DOI: 10.1073/Pnas.1415107111 |
0.412 |
|
2015 |
Smith MJ, Packard TA, O'Neill SK, Henry Dunand CJ, Huang M, Fitzgerald-Miller L, Stowell D, Hinman RM, Wilson PC, Gottlieb PA, Cambier JC. Loss of anergic B cells in prediabetic and new-onset type 1 diabetic patients. Diabetes. 64: 1703-12. PMID 25524915 DOI: 10.2337/Db13-1798 |
0.472 |
|
2014 |
White MJ, McArthur K, Metcalf D, Lane RM, Cambier JC, Herold MJ, van Delft MF, Bedoui S, Lessene G, Ritchie ME, Huang DC, Kile BT. Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production. Cell. 159: 1549-62. PMID 25525874 DOI: 10.1016/J.Cell.2014.11.036 |
0.313 |
|
2014 |
Hinman RM, Cambier JC. Role of B lymphocytes in the pathogenesis of type 1 diabetes. Current Diabetes Reports. 14: 543. PMID 25189436 DOI: 10.1007/S11892-014-0543-8 |
0.489 |
|
2014 |
Luo W, Mayeux J, Gutierrez T, Russell L, Getahun A, Müller J, Tedder T, Parnes J, Rickert R, Nitschke L, Cambier J, Satterthwaite AB, Garrett-Sinha LA. A balance between B cell receptor and inhibitory receptor signaling controls plasma cell differentiation by maintaining optimal Ets1 levels. Journal of Immunology (Baltimore, Md. : 1950). 193: 909-20. PMID 24929000 DOI: 10.4049/Jimmunol.1400666 |
0.54 |
|
2014 |
Hinman RM, Smith MJ, Cambier JC. B cells and type 1 diabetes ...in mice and men. Immunology Letters. 160: 128-32. PMID 24472603 DOI: 10.1016/J.Imlet.2014.01.010 |
0.473 |
|
2014 |
Hardy IR, Anceriz N, Rousseau F, Seefeldt MB, Hatterer E, Irla M, Buatois V, Chatel LE, Getahun A, Fletcher A, Cons L, Pontini G, Hertzberg NA, Magistrelli G, Malinge P, ... ... Cambier JC, et al. Anti-CD79 antibody induces B cell anergy that protects against autoimmunity. Journal of Immunology (Baltimore, Md. : 1950). 192: 1641-50. PMID 24442438 DOI: 10.4049/Jimmunol.1302672 |
0.81 |
|
2014 |
White MJ, McArthur K, Metcalf D, Cambier J, Bedoui S, Ritchie M, Huang DC, Kile B. 197 Cytokine. 70: 75-76. DOI: 10.1016/J.Cyto.2014.07.204 |
0.31 |
|
2013 |
Packard TA, Cambier JC. B lymphocyte antigen receptor signaling: initiation, amplification, and regulation. F1000prime Reports. 5: 40. PMID 24167721 DOI: 10.12703/P5-40 |
0.525 |
|
2013 |
Bounab Y, Getahun A, Cambier JC, Daëron M. Phosphatase regulation of immunoreceptor signaling in T cells, B cells and mast cells. Current Opinion in Immunology. 25: 313-20. PMID 23684445 DOI: 10.1016/J.Coi.2013.04.001 |
0.483 |
|
2013 |
Cambier JC. Autoimmunity risk alleles: hotspots in B cell regulatory signaling pathways. The Journal of Clinical Investigation. 123: 1928-31. PMID 23619359 DOI: 10.1172/Jci69289 |
0.386 |
|
2012 |
Clambey ET, McNamee EN, Westrich JA, Glover LE, Campbell EL, Jedlicka P, de Zoeten EF, Cambier JC, Stenmark KR, Colgan SP, Eltzschig HK. Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa. Proceedings of the National Academy of Sciences of the United States of America. 109: E2784-93. PMID 22988108 DOI: 10.1073/Pnas.1202366109 |
0.331 |
|
2012 |
Getahun A, Smith MJ, Kogut I, van Dyk LF, Cambier JC. Retention of anergy and inhibition of antibody responses during acute γ herpesvirus 68 infection. Journal of Immunology (Baltimore, Md. : 1950). 189: 2965-74. PMID 22904300 DOI: 10.4049/Jimmunol.1201407 |
0.439 |
|
2012 |
Jin L, Cambier JC. SMIP-016 in action: CD37 as a death receptor. Cancer Cell. 21: 597-8. PMID 22624709 DOI: 10.1016/J.Ccr.2012.04.034 |
0.392 |
|
2012 |
Kogut I, Scholz JL, Cancro MP, Cambier JC. B cell maintenance and function in aging. Seminars in Immunology. 24: 342-9. PMID 22560930 DOI: 10.1016/J.Smim.2012.04.004 |
0.412 |
|
2012 |
Khalil AM, Cambier JC, Shlomchik MJ. B cell receptor signal transduction in the GC is short-circuited by high phosphatase activity. Science (New York, N.Y.). 336: 1178-81. PMID 22555432 DOI: 10.1126/Science.1213368 |
0.529 |
|
2012 |
Waterman PM, Marschner S, Brandl E, Cambier JC. The inositol 5-phosphatase SHIP-1 and adaptors Dok-1 and 2 play central roles in CD4-mediated inhibitory signaling Immunology Letters. 143: 122-130. PMID 22370159 DOI: 10.1016/J.Imlet.2012.02.009 |
0.452 |
|
2012 |
O'Brien RL, Chain JL, Aydintug MK, Bohrer-Kunter D, Huang Y, Hardy IR, Cambier JC, Lahmers K, Nuhsbaum T, Davidson R, Sun D, Born WK. αβ TCR⺠T cells, but not B cells, promote autoimmune keratitis in b10 mice lacking γδ T cells. Investigative Ophthalmology & Visual Science. 53: 301-8. PMID 22199243 DOI: 10.1167/Iovs.11-8855 |
0.8 |
|
2012 |
Xu LG, Jin L, Zhang BC, Akerlund LJ, Shu HB, Cambier JC. VISA is required for B cell expression of TLR7. Journal of Immunology (Baltimore, Md. : 1950). 188: 248-58. PMID 22105994 DOI: 10.4049/Jimmunol.1100918 |
0.486 |
|
2011 |
O'Neill SK, Getahun A, Gauld SB, Merrell KT, Tamir I, Smith MJ, Dal Porto JM, Li QZ, Cambier JC. Monophosphorylation of CD79a and CD79b ITAM motifs initiates a SHIP-1 phosphatase-mediated inhibitory signaling cascade required for B cell anergy. Immunity. 35: 746-56. PMID 22078222 DOI: 10.1016/J.Immuni.2011.10.011 |
0.529 |
|
2011 |
Yarkoni Y, Cambier JC. Differential STIM1 expression in T and B cell subsets suggests a role in determining antigen receptor signal amplitude. Molecular Immunology. 48: 1851-8. PMID 21663969 DOI: 10.1016/J.Molimm.2011.05.006 |
0.402 |
|
2011 |
Lukin K, Fields S, Guerrettaz L, Straign D, Rodriguez V, Zandi S, Månsson R, Cambier JC, Sigvardsson M, Hagman J. A dose-dependent role for EBF1 in repressing non-B-cell-specific genes. European Journal of Immunology. 41: 1787-93. PMID 21469119 DOI: 10.1002/Eji.201041137 |
0.8 |
|
2011 |
Van Den Broeck A, Cambier J. B cells talk to their progenitors. Blood. 117: 2985-6. PMID 21415272 DOI: 10.1182/Blood-2011-02-332544 |
0.411 |
|
2011 |
Dhirapong A, Lleo A, Yang GX, Tsuneyama K, Dunn R, Kehry M, Packard TA, Cambier JC, Liu FT, Lindor K, Coppel RL, Ansari AA, Gershwin ME. B cell depletion therapy exacerbates murine primary biliary cirrhosis Hepatology. 53: 527-535. PMID 21274873 DOI: 10.1002/Hep.24044 |
0.437 |
|
2010 |
Waterman PM, Cambier JC. The conundrum of inhibitory signaling by ITAM-containing immunoreceptors: Potential molecular mechanisms Febs Letters. 584: 4878-4882. PMID 20875413 DOI: 10.1016/J.Febslet.2010.09.029 |
0.423 |
|
2010 |
Chan MA, Gigliotti NM, Matangkasombut P, Gauld SB, Cambier JC, Rosenwasser LJ. CD23-mediated cell signaling in human B cells differs from signaling in cells of the monocytic lineage. Clinical Immunology (Orlando, Fla.). 137: 330-6. PMID 20805040 DOI: 10.1016/J.Clim.2010.08.005 |
0.506 |
|
2010 |
Yarkoni Y, Getahun A, Cambier JC. Molecular underpinning of B-cell anergy. Immunological Reviews. 237: 249-63. PMID 20727040 DOI: 10.1111/J.1600-065X.2010.00936.X |
0.501 |
|
2010 |
Cady CT, Powell MS, Harbeck RJ, Giclas PC, Murphy JR, Katial RK, Weber RW, Hogarth PM, Johnson S, Bonvini E, Koenig S, Cambier JC. IgG antibodies produced during subcutaneous allergen immunotherapy mediate inhibition of basophil activation via a mechanism involving both FcgammaRIIA and FcgammaRIIB. Immunology Letters. 130: 57-65. PMID 20004689 DOI: 10.1016/J.Imlet.2009.12.001 |
0.395 |
|
2010 |
Cambier JC, Getahun A. B cell activation versus anergy; the antigen receptor as a molecular switch. Immunology Letters. 128: 6-7. PMID 19808046 DOI: 10.1016/J.Imlet.2009.09.006 |
0.516 |
|
2009 |
Getahun A, O'Neill SK, Cambier JC. Establishing anergy as a bona fide in vivo mechanism of B cell tolerance. Journal of Immunology (Baltimore, Md. : 1950). 183: 5439-41. PMID 19843930 DOI: 10.4049/Jimmunol.0990088 |
0.33 |
|
2009 |
Jackson L, Cady CT, Cambier JC. TLR4-mediated signaling induces MMP9-dependent cleavage of B cell surface CD23. Journal of Immunology (Baltimore, Md. : 1950). 183: 2585-92. PMID 19635918 DOI: 10.4049/Jimmunol.0803660 |
0.406 |
|
2009 |
O'Neill SK, Liu E, Cambier JC. Change you can B(cell)eive in: recent progress confirms a critical role for B cells in type 1 diabetes. Current Opinion in Endocrinology, Diabetes, and Obesity. 16: 293-8. PMID 19502979 DOI: 10.1097/Med.0B013E32832E06A7 |
0.435 |
|
2009 |
O'Neill SK, Veselits ML, Zhang M, Labno C, Cao Y, Finnegan A, Uccellini M, Alegre ML, Cambier JC, Clark MR. Endocytic sequestration of the B cell antigen receptor and toll-like receptor 9 in anergic cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 6262-7. PMID 19332776 DOI: 10.1073/Pnas.0812922106 |
0.501 |
|
2009 |
Decoté-Ricardo D, Chagas KK, Rocha JD, Redner P, Lopes UG, Cambier JC, Barros de Arruda L, Peçanha LM. Modulation of in vitro murine B-lymphocyte response by curcumin. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 16: 982-8. PMID 19303754 DOI: 10.1016/J.Phymed.2009.01.004 |
0.472 |
|
2009 |
Crowley JE, Stadanlick JE, Cambier JC, Cancro MP. FcgammaRIIB signals inhibit BLyS signaling and BCR-mediated BLyS receptor up-regulation. Blood. 113: 1464-73. PMID 18791164 DOI: 10.1182/Blood-2008-02-138651 |
0.504 |
|
2008 |
Cady CT, Rice JS, Ott VL, Cambier JC. Regulation of hematopoietic cell function by inhibitory immunoglobulin G receptors and their inositol lipid phosphatase effectors. Immunological Reviews. 224: 44-57. PMID 18759919 DOI: 10.1111/J.1600-065X.2008.00663.X |
0.76 |
|
2008 |
Li Y, Chen F, Putt M, Koo YK, Madaio M, Cambier JC, Cohen PL, Eisenberg RA. B cell depletion with anti-CD79 mAbs ameliorates autoimmune disease in MRL/lpr mice. Journal of Immunology (Baltimore, Md. : 1950). 181: 2961-72. PMID 18713966 DOI: 10.4049/Jimmunol.181.5.2961 |
0.464 |
|
2008 |
Guerrettaz LM, Johnson SA, Cambier JC. Acquired hematopoietic stem cell defects determine B-cell repertoire changes associated with aging. Proceedings of the National Academy of Sciences of the United States of America. 105: 11898-902. PMID 18697924 DOI: 10.1073/Pnas.0805498105 |
0.81 |
|
2008 |
Jin L, Waterman PM, Jonscher KR, Short CM, Reisdorph NA, Cambier JC. MPYS, a novel membrane tetraspanner, is associated with major histocompatibility complex class II and mediates transduction of apoptotic signals. Molecular and Cellular Biology. 28: 5014-26. PMID 18559423 DOI: 10.1128/Mcb.00640-08 |
0.418 |
|
2008 |
Jin L, Stolpa JC, Young RM, Pugh-Bernard AE, Refaeli Y, Cambier JC. MHC class II structural requirements for the association with Igalpha/beta, and signaling of calcium mobilization and cell death. Immunology Letters. 116: 184-94. PMID 18194817 DOI: 10.1016/J.Imlet.2007.11.023 |
0.792 |
|
2007 |
Rider DA, Havenith CE, de Ridder R, Schuurman J, Favre C, Cooper JC, Walker S, Baadsgaard O, Marschner S, vandeWinkel JG, Cambier J, Parren PW, Alexander DR. A human CD4 monoclonal antibody for the treatment of T-cell lymphoma combines inhibition of T-cell signaling by a dual mechanism with potent Fc-dependent effector activity. Cancer Research. 67: 9945-53. PMID 17942927 DOI: 10.1158/0008-5472.Can-07-1148 |
0.457 |
|
2007 |
Conrad FJ, Rice JS, Cambier JC. Multiple paths to loss of anergy and gain of autoimmunity. Autoimmunity. 40: 418-24. PMID 17729035 DOI: 10.1080/08916930701464723 |
0.769 |
|
2007 |
Lyubchenko T, Dal Porto JM, Holers VM, Cambier JC. Cutting edge: Complement (C3d)-linked antigens break B cell anergy Journal of Immunology. 179: 2695-2699. PMID 17709481 DOI: 10.4049/Jimmunol.179.5.2695 |
0.503 |
|
2007 |
Cambier JC, Gauld SB, Merrell KT, Vilen BJ. B-cell anergy: from transgenic models to naturally occurring anergic B cells? Nature Reviews. Immunology. 7: 633-43. PMID 17641666 DOI: 10.1038/Nri2133 |
0.44 |
|
2007 |
Velez MG, Kane M, Liu S, Gauld SB, Cambier JC, Torres RM, Pelanda R. Ig allotypic inclusion does not prevent B cell development or response. Journal of Immunology (Baltimore, Md. : 1950). 179: 1049-57. PMID 17617597 DOI: 10.4049/Jimmunol.179.2.1049 |
0.52 |
|
2007 |
Brauweiler A, Merrell K, Gauld SB, Cambier JC. Cutting Edge: Acute and chronic exposure of immature B cells to antigen leads to impaired homing and SHIP1-dependent reduction in stromal cell-derived factor-1 responsiveness. Journal of Immunology (Baltimore, Md. : 1950). 178: 3353-7. PMID 17339427 DOI: 10.4049/Jimmunol.178.6.3353 |
0.434 |
|
2007 |
Mills DM, Stolpa JC, Cambier JC. Modulation of MHC class II signal transduction by CD19. Advances in Experimental Medicine and Biology. 596: 139-48. PMID 17338182 DOI: 10.1007/0-387-46530-8_12 |
0.772 |
|
2007 |
Lyubchenko T, Porto JD, Holers VM, Cambier JC. Complement C3dg-enhanced antigen breaks B cell anergy in Ars/A1 murine model Molecular Immunology. 44: 211. DOI: 10.1016/J.Molimm.2006.07.150 |
0.379 |
|
2006 |
Merrell KT, Benschop RJ, Gauld SB, Aviszus K, Decote-Ricardo D, Wysocki LJ, Cambier JC. Identification of anergic B cells within a wild-type repertoire. Immunity. 25: 953-62. PMID 17174121 DOI: 10.1016/J.Immuni.2006.10.017 |
0.511 |
|
2006 |
Pugh-Bernard AE, Cambier JC. B cell receptor signaling in human systemic lupus erythematosus. Current Opinion in Rheumatology. 18: 451-5. PMID 16896281 DOI: 10.1097/01.Bor.0000240353.99808.5F |
0.491 |
|
2006 |
Powell MS, Barnes NC, Bradford TM, Musgrave IF, Wines BD, Cambier JC, Hogarth PM. Alteration of the Fc gamma RIIa dimer interface affects receptor signaling but not ligand binding. Journal of Immunology (Baltimore, Md. : 1950). 176: 7489-94. PMID 16751395 DOI: 10.4049/Jimmunol.176.12.7489 |
0.413 |
|
2006 |
Gauld SB, Merrell KT, Cambier JC. Silencing of autoreactive B cells by anergy: a fresh perspective. Current Opinion in Immunology. 18: 292-7. PMID 16616480 DOI: 10.1016/J.Coi.2006.03.015 |
0.543 |
|
2005 |
Gauld SB, Benschop RJ, Merrell KT, Cambier JC. Maintenance of B cell anergy requires constant antigen receptor occupancy and signaling. Nature Immunology. 6: 1160-7. PMID 16200069 DOI: 10.1038/Ni1256 |
0.498 |
|
2005 |
Lyubchenko T, Dal Porto J, Cambier JC, Holers VM. Coligation of the B cell receptor with complement receptor type 2 (CR2/CD21) using its natural ligand C3dg: Activation without engagement of an inhibitory signaling pathway Journal of Immunology. 174: 3264-3272. PMID 15749857 DOI: 10.4049/Jimmunol.174.6.3264 |
0.481 |
|
2005 |
Ott VL, Moffitt LA, Cambier JC. Study of SHIP-binding cell surface proteins suggests c-kit as a SHIP-interacting receptor in mast cells Signal Transduction. 5: 28-39. DOI: 10.1002/Sita.200400029 |
0.504 |
|
2004 |
Gauld SB, Cambier JC. Src-family kinases in B-cell development and signaling. Oncogene. 23: 8001-6. PMID 15489917 DOI: 10.1038/Sj.Onc.1208075 |
0.509 |
|
2004 |
Isnardi I, Lesourne R, Bruhns P, Fridman WH, Cambier JC, Daëron M. Two distinct tyrosine-based motifs enable the inhibitory receptor FcgammaRIIB to cooperatively recruit the inositol phosphatases SHIP1/2 and the adapters Grb2/Grap. The Journal of Biological Chemistry. 279: 51931-8. PMID 15456754 DOI: 10.1074/Jbc.M410261200 |
0.411 |
|
2004 |
Dal Porto JM, Burke K, Cambier JC. Regulation of BCR signal transduction in B-1 cells requires the expression of the Src family kinase Lck. Immunity. 21: 443-53. PMID 15357954 DOI: 10.1016/J.Immuni.2004.07.018 |
0.516 |
|
2004 |
Johnson SA, Cambier JC. Ageing, autoimmunity and arthritis: senescence of the B cell compartment - implications for humoral immunity. Arthritis Research & Therapy. 6: 131-9. PMID 15225355 DOI: 10.1186/Ar1180 |
0.476 |
|
2004 |
Dal Porto JM, Gauld SB, Merrell KT, Mills D, Pugh-Bernard AE, Cambier J. B cell antigen receptor signaling 101. Molecular Immunology. 41: 599-613. PMID 15219998 DOI: 10.1016/J.Molimm.2004.04.008 |
0.533 |
|
2004 |
Jordan MB, Mills DM, Kappler J, Marrack P, Cambier JC. Promotion of B cell immune responses via an alum-induced myeloid cell population. Science (New York, N.Y.). 304: 1808-10. PMID 15205534 DOI: 10.1126/Science.1089926 |
0.462 |
|
2004 |
Brauweiler AM, Cambier JC. Autonomous SHIP-dependent FcgammaR signaling in pre-B cells leads to inhibition of cell migration and induction of cell death. Immunology Letters. 92: 75-81. PMID 15081530 DOI: 10.1016/J.Imlet.2003.11.028 |
0.562 |
|
2004 |
Mills DM, Stolpa JC, Cambier JC. Cognate B cell signaling via MHC class II: differential regulation of B cell antigen receptor and MHC class II/Ig-alpha beta signaling by CD22. Journal of Immunology (Baltimore, Md. : 1950). 172: 195-201. PMID 14688326 DOI: 10.4049/Jimmunol.172.1.195 |
0.807 |
|
2003 |
Mills DM, Cambier JC. B lymphocyte activation during cognate interactions with CD4+ T lymphocytes: molecular dynamics and immunologic consequences. Seminars in Immunology. 15: 325-9. PMID 15001171 DOI: 10.1016/J.Smim.2003.09.004 |
0.438 |
|
2003 |
Ott VL, Cambier JC, Kappler J, Marrack P, Swanson BJ. Mast cell-dependent migration of effector CD8+ T cells through production of leukotriene B4. Nature Immunology. 4: 974-81. PMID 12949532 DOI: 10.1038/Ni971 |
0.406 |
|
2003 |
Nakamura K, Yube K, Miyatake A, Cambier JC, Hirashima M. Involvement of CD4 D3-D4 membrane proximal extracellular domain for the inhibitory effect of oxidative stress on activation-induced CD4 down-regulation and its possible role for T cell activation. Molecular Immunology. 39: 909-21. PMID 12695117 DOI: 10.1016/S0161-5890(03)00030-0 |
0.358 |
|
2003 |
Brauweiler AM, Cambier JC. Fc gamma RIIB activation leads to inhibition of signalling by independently ligated receptors. Biochemical Society Transactions. 31: 281-5. PMID 12546702 DOI: 10.1042/Bst0310281 |
0.561 |
|
2002 |
Chumley MJ, Dal Porto JM, Cambier JC. The unique antigen receptor signaling phenotype of B-1 cells is influenced by locale but induced by antigen. Journal of Immunology (Baltimore, Md. : 1950). 169: 1735-43. PMID 12165494 DOI: 10.4049/Jimmunol.169.4.1735 |
0.512 |
|
2002 |
Gauld SB, Dal Porto JM, Cambier JC. B cell antigen receptor signaling: roles in cell development and disease. Science (New York, N.Y.). 296: 1641-2. PMID 12040177 DOI: 10.1126/Science.1071546 |
0.529 |
|
2002 |
Marschner S, Hünig T, Cambier JC, Finkel TH. Ligation of human CD4 interferes with antigen-induced activation of primary T cells. Immunology Letters. 82: 131-9. PMID 12008044 DOI: 10.1016/S0165-2478(02)00028-7 |
0.418 |
|
2002 |
Johnson SA, Rozzo SJ, Cambier JC. Aging-dependent exclusion of antigen-inexperienced cells from the peripheral B cell repertoire. Journal of Immunology (Baltimore, Md. : 1950). 168: 5014-23. PMID 11994453 DOI: 10.4049/Jimmunol.168.10.5014 |
0.472 |
|
2002 |
Ott VL, Tamir I, Niki M, Pandolfi PP, Cambier JC. Downstream of kinase, p62(dok), is a mediator of Fc gamma IIB inhibition of Fc epsilon RI signaling. Journal of Immunology (Baltimore, Md. : 1950). 168: 4430-9. PMID 11970986 DOI: 10.4049/Jimmunol.168.9.4430 |
0.498 |
|
2002 |
Vilen BJ, Burke KM, Sleater M, Cambier JC. Transmodulation of BCR signaling by transduction-incompetent antigen receptors: implications for impaired signaling in anergic B cells. Journal of Immunology (Baltimore, Md. : 1950). 168: 4344-51. PMID 11970976 DOI: 10.4049/Jimmunol.168.9.4344 |
0.513 |
|
2002 |
Ott VL, Cambier JC. Introduction: multifaceted roles of lipids and their catabolites in immune cell signaling. Seminars in Immunology. 14: 1-6. PMID 11884225 DOI: 10.1006/Smim.2001.0336 |
0.381 |
|
2001 |
Bannish G, Fuentes-Pananá EM, Cambier JC, Pear WS, Monroe JG. Ligand-independent signaling functions for the B lymphocyte antigen receptor and their role in positive selection during B lymphopoiesis Journal of Experimental Medicine. 194: 1583-1596. PMID 11733573 DOI: 10.1084/Jem.194.11.1583 |
0.511 |
|
2001 |
Benschop RJ, Brandl E, Chan AC, Cambier JC. Unique signaling properties of B cell antigen receptor in mature and immature B cells: implications for tolerance and activation. Journal of Immunology (Baltimore, Md. : 1950). 167: 4172-9. PMID 11591737 DOI: 10.4049/Jimmunol.167.8.4172 |
0.511 |
|
2001 |
Ott VL, Fong DC, Cambier JC. Fc gamma RIIB as a potential molecular target for intravenous gamma globulin therapy. The Journal of Allergy and Clinical Immunology. 108: S95-8. PMID 11586273 DOI: 10.1067/Mai.2001.117822 |
0.79 |
|
2001 |
Kraus M, Pao LI, Reichlin A, Hu Y, Canono B, Cambier JC, Nussenzweig MC, Rajewsky K. Interference with immunoglobulin (Ig)α immunoreceptor tyrosine-based activation motif (ITAM) phosphorylation modulates or blocks B cell development, depending on the availability of an Igβ cytoplasmic tail Journal of Experimental Medicine. 194: 455-469. PMID 11514602 DOI: 10.1084/Jem.194.4.455 |
0.526 |
|
2001 |
Brauweiler A, Tamir I, Marschner S, Helgason CD, Cambier JC. Partially distinct molecular mechanisms mediate inhibitory FcgammaRIIB signaling in resting and activated B cells. Journal of Immunology (Baltimore, Md. : 1950). 167: 204-11. PMID 11418650 DOI: 10.4049/Jimmunol.167.1.204 |
0.563 |
|
2001 |
Lang P, Stolpa JC, Freiberg BA, Crawford F, Kappler J, Kupfer A, Cambier JC. TCR-induced transmembrane signaling by peptide/MHC class II via associated Ig-alpha/beta dimers. Science (New York, N.Y.). 291: 1537-40. PMID 11222857 DOI: 10.1126/Science.291.5508.1537 |
0.801 |
|
2001 |
Benschop RJ, Aviszus K, Zhang X, Manser T, Cambier JC, Wysocki LJ. Activation and anergy in bone marrow B cells of a novel immunoglobulin transgenic mouse that is both hapten specific and autoreactive. Immunity. 14: 33-43. PMID 11163228 DOI: 10.1016/S1074-7613(01)00087-5 |
0.462 |
|
2001 |
Brauweiler AM, Tamir I, Cambier JC. Bilevel control of B-cell activation by the inositol 5-phosphatase SHIP. Immunological Reviews. 176: 69-74. PMID 11043768 DOI: 10.1034/j.1600-065X.2000.00612.x |
0.388 |
|
2001 |
Cambier J, Brauweiler A, Marschner S, Tamir I. SHIPs and their Doks in regulation of lymphocyte function Biochemical Society Transactions. 29: A109-A109. DOI: 10.1042/Bst029A109A |
0.304 |
|
2001 |
Jensen WA, Marschner S, Ott VL, Cambier JC. FcγRIIB-mediated inhibition of T-cell receptor signal transduction involves the phosphorylation of SH2-containing inositol 5-phosphatase (SHIP), dephosphorylation of the linker of activated T-cells (LAT) and inhibition of calcium mobilization Biochemical Society Transactions. 29: 840-846. DOI: 10.1042/Bst0290840 |
0.504 |
|
2000 |
Buhl AM, Nemazee D, Cambier JC, Rickert R, Hertz M. B-cell antigen receptor competence regulates B-lymphocyte selection and survival. Immunological Reviews. 176: 141-53. PMID 11043774 |
0.421 |
|
2000 |
Fong DC, Brauweiler A, Minskoff SA, Bruhns P, Tamir I, Mellman I, Daeron M, Cambier JC. Mutational analysis reveals multiple distinct sites within Fc gamma receptor IIB that function in inhibitory signaling. Journal of Immunology (Baltimore, Md. : 1950). 165: 4453-62. PMID 11035084 DOI: 10.4049/Jimmunol.165.8.4453 |
0.813 |
|
2000 |
Ott VL, Cambier JC. Activating and inhibitory signaling in mast cells: new opportunities for therapeutic intervention? The Journal of Allergy and Clinical Immunology. 106: 429-40. PMID 10984360 DOI: 10.1067/Mai.2000.109428 |
0.505 |
|
2000 |
Kepley CL, Cambier JC, Morel PA, Lujan D, Ortega E, Wilson BS, Oliver JM. Negative regulation of FcepsilonRI signaling by FcgammaRII costimulation in human blood basophils. The Journal of Allergy and Clinical Immunology. 106: 337-48. PMID 10932079 DOI: 10.1067/Mai.2000.107931 |
0.499 |
|
2000 |
Giallourakis C, Kashiwada M, Pan PY, Danial N, Jiang H, Cambier J, Coggeshall KM, Rothman P. Positive regulation of interleukin-4-mediated proliferation by the SH2-containing inositol-5'-phosphatase. The Journal of Biological Chemistry. 275: 29275-82. PMID 10875931 DOI: 10.1074/Jbc.M002853200 |
0.323 |
|
2000 |
Brauweiler A, Tamir I, Dal Porto J, Benschop RJ, Helgason CD, Humphries RK, Freed JH, Cambier JC. Differential regulation of B cell development, activation, and death by the src homology 2 domain-containing 5' inositol phosphatase (SHIP). The Journal of Experimental Medicine. 191: 1545-54. PMID 10790429 DOI: 10.1084/Jem.191.9.1545 |
0.547 |
|
2000 |
Tamir I, Dal Porto JM, Cambier JC. Cytoplasmic protein tyrosine phosphatases SHP-1 and SHP-2: regulators of B cell signal transduction. Current Opinion in Immunology. 12: 307-15. PMID 10781410 DOI: 10.1016/S0952-7915(00)00092-3 |
0.452 |
|
2000 |
Chumley MJ, Dal Porto JM, Kawaguchi S, Cambier JC, Nemazee D, Hardy RR. A VH11V kappa 9 B cell antigen receptor drives generation of CD5+ B cells both in vivo and in vitro. Journal of Immunology (Baltimore, Md. : 1950). 164: 4586-93. PMID 10779761 DOI: 10.4049/Jimmunol.164.9.4586 |
0.509 |
|
2000 |
Tamir I, Stolpa JC, Helgason CD, Nakamura K, Bruhns P, Daeron M, Cambier JC. The RasGAP-binding protein p62dok is a mediator of inhibitory FcgammaRIIB signals in B cells. Immunity. 12: 347-58. PMID 10755621 DOI: 10.1016/S1074-7613(00)80187-9 |
0.809 |
|
2000 |
Nakamura K, Brauweiler A, Cambier JC. Effects of Src homology domain 2 (SH2)-containing inositol phosphatase (SHIP), SH2-containing phosphotyrosine phosphatase (SHP)-1, and SHP-2 SH2 decoy proteins on Fc gamma RIIB1-effector interactions and inhibitory functions. Journal of Immunology (Baltimore, Md. : 1950). 164: 631-8. PMID 10623804 DOI: 10.4049/Jimmunol.164.2.631 |
0.471 |
|
1999 |
Fong DC, Cambier JC. Inhibitory receptors and their modes of action. Cold Spring Harbor Symposia On Quantitative Biology. 64: 329-34. PMID 11232303 DOI: 10.1101/Sqb.1999.64.329 |
0.755 |
|
1999 |
Benschop RJ, Melamed D, Nemazee D, Cambier JC. Distinct signal thresholds for the unique antigen receptor-linked gene expression programs in mature and immature B cells. The Journal of Experimental Medicine. 190: 749-56. PMID 10499913 DOI: 10.1084/Jem.190.6.749 |
0.535 |
|
1999 |
Famiglietti SJ, Nakamura K, Cambier JC. Unique features of SHIP, SHP-1 and SHP-2 binding to FcgammaRIIb revealed by surface plasmon resonance analysis. Immunology Letters. 68: 35-40. PMID 10397153 DOI: 10.1016/S0165-2478(99)00027-9 |
0.363 |
|
1999 |
Benschop RJ, Cambier JC. B cell development: signal transduction by antigen receptors and their surrogates. Current Opinion in Immunology. 11: 143-51. PMID 10322153 DOI: 10.1016/S0952-7915(99)80025-9 |
0.537 |
|
1999 |
Vilen BJ, Nakamura T, Cambier JC. Antigen-stimulated dissociation of BCR mlg from Ig-α/Ig-β: Implications for receptor desensitization Immunity. 10: 239-248. PMID 10072076 DOI: 10.1016/S1074-7613(00)80024-2 |
0.448 |
|
1998 |
Venkataraman C, Chelvarajan RL, Cambier JC, Bondada S. Interleukin-4 overcomes the negative influence of cyclic AMP accumulation on antigen receptor stimulated B lymphocytes. Molecular Immunology. 35: 997-1014. PMID 9881695 DOI: 10.1016/S0161-5890(98)00068-6 |
0.473 |
|
1998 |
Venkataraman C, Lu PJ, Buhl AM, Chen CS, Cambier JC, Bondada S. CD72-mediated B cell activation involves recruitment of CD19 and activation of phosphatidylinositol 3-kinase. European Journal of Immunology. 28: 3003-16. PMID 9808169 DOI: 10.1002/(Sici)1521-4141(199810)28:10<3003::Aid-Immu3003>3.0.Co;2-W |
0.384 |
|
1998 |
Kouskoff V, Famiglietti S, Lacaud G, Lang P, Rider JE, Kay BK, Cambier JC, Nemazee D. Antigens varying in affinity for the B cell receptor induce differential B lymphocyte responses. The Journal of Experimental Medicine. 188: 1453-64. PMID 9782122 DOI: 10.1084/Jem.188.8.1453 |
0.562 |
|
1998 |
Tamir I, Cambier JC. Antigen receptor signaling: integration of protein tyrosine kinase functions. Oncogene. 17: 1353-64. PMID 9779983 DOI: 10.1038/Sj.Onc.1202187 |
0.51 |
|
1998 |
Buhl AM, Cambier JC. Co-receptor and accessory regulation of B-cell antigen receptor signal transduction. Immunological Reviews. 160: 127-38. PMID 9476671 DOI: 10.1111/J.1600-065X.1997.Tb01033.X |
0.541 |
|
1998 |
Malbec O, Fong DC, Turner M, Tybulewicz VL, Cambier JC, Fridman WH, Daëron M. Fc epsilon receptor I-associated lyn-dependent phosphorylation of Fc gamma receptor IIB during negative regulation of mast cell activation. Journal of Immunology (Baltimore, Md. : 1950). 160: 1647-58. PMID 9469421 |
0.811 |
|
1998 |
Melamed D, Benschop RJ, Cambier JC, Nemazee D. Developmental regulation of B lymphocyte immune tolerance compartmentalizes clonal selection from receptor selection. Cell. 92: 173-82. PMID 9458042 DOI: 10.1016/S0092-8674(00)80912-5 |
0.478 |
|
1997 |
Buhl AM, Pleiman CM, Rickert RC, Cambier JC. Qualitative regulation of B cell antigen receptor signaling by CD19: selective requirement for PI3-kinase activation, inositol-1,4,5-trisphosphate production and Ca2+ mobilization. The Journal of Experimental Medicine. 186: 1897-910. PMID 9382888 DOI: 10.1084/Jem.186.11.1897 |
0.496 |
|
1997 |
Vély F, Olivero S, Olcese L, Moretta A, Damen JE, Liu L, Krystal G, Cambier JC, Daëron M, Vivier E. Differential association of phosphatases with hematopoietic co-receptors bearing immunoreceptor tyrosine-based inhibition motifs. European Journal of Immunology. 27: 1994-2000. PMID 9295037 DOI: 10.1002/Eji.1830270825 |
0.461 |
|
1997 |
Hippen KL, Buhl AM, D'Ambrosio D, Nakamura K, Persin C, Cambier JC. Fc gammaRIIB1 inhibition of BCR-mediated phosphoinositide hydrolysis and Ca2+ mobilization is integrated by CD19 dephosphorylation. Immunity. 7: 49-58. PMID 9252119 DOI: 10.1016/S1074-7613(00)80509-9 |
0.475 |
|
1997 |
Cambier JC. Inhibitory receptors abound? Proceedings of the National Academy of Sciences of the United States of America. 94: 5993-5. PMID 9177155 DOI: 10.1073/Pnas.94.12.5993 |
0.408 |
|
1997 |
Jensen WA, Pleiman CM, Beaufils P, Wegener AM, Malissen B, Cambier JC. Qualitatively distinct signaling through T cell antigen receptor subunits. European Journal of Immunology. 27: 707-16. PMID 9079813 DOI: 10.1002/Eji.1830270320 |
0.449 |
|
1996 |
Fong DC, Malbec O, Arock M, Cambier JC, Fridman WH, Daëron M. Selective in vivo recruitment of the phosphatidylinositol phosphatase SHIP by phosphorylated Fc gammaRIIB during negative regulation of IgE-dependent mouse mast cell activation. Immunology Letters. 54: 83-91. PMID 9052859 DOI: 10.1016/S0165-2478(96)02654-5 |
0.822 |
|
1996 |
D'Ambrosio D, Fong DC, Cambier JC. The SHIP phosphatase becomes associated with Fc gammaRIIB1 and is tyrosine phosphorylated during 'negative' signaling. Immunology Letters. 54: 77-82. PMID 9052858 DOI: 10.1016/S0165-2478(96)02653-3 |
0.816 |
|
1996 |
Makida R, Hofer MF, Takase K, Cambier JC, Leung DY. Bacterial superantigens induce V beta-specific T cell receptor internalization. Molecular Immunology. 33: 891-900. PMID 8845021 DOI: 10.1016/0161-5890(96)84615-3 |
0.346 |
|
1996 |
D'Ambrosio D, Hippen KL, Cambier JC. Distinct mechanisms mediate SHC association with the activated and resting B cell antigen receptor. European Journal of Immunology. 26: 1960-5. PMID 8765045 DOI: 10.1002/Eji.1830260842 |
0.406 |
|
1996 |
Campbell KS, Bedzyk WD, Cambier JC. Manipulation of B cell antigen receptor tyrosine phosphorylation using aluminum fluoride and sodium orthovanadate. Molecular Immunology. 32: 1283-94. PMID 8559152 DOI: 10.1016/0161-5890(95)00088-7 |
0.4 |
|
1996 |
RABINOVITCH N, PATEL H, DAMBROSIO D, CAMBIER J, GELFAND E. 979 Down-regulation of human B-cell antigen receptor signaling by Fc receptor cross-linking Journal of Allergy and Clinical Immunology. 97: 427-427. DOI: 10.1016/S0091-6749(96)81197-3 |
0.381 |
|
1995 |
Cambier JC, Johnson SA. Differential binding activity of ARH1/TAM motifs. Immunology Letters. 44: 77-80. PMID 7797258 DOI: 10.1016/0165-2478(94)00196-X |
0.434 |
|
1995 |
Davila DR, Davis DP, Campbell K, Cambier JC, Zigmond LA, Burchiel SW. Role of alterations in Ca(2+)-associated signaling pathways in the immunotoxicity of polycyclic aromatic hydrocarbons. Journal of Toxicology and Environmental Health. 45: 101-26. PMID 7783249 DOI: 10.1080/15287399509531985 |
0.436 |
|
1995 |
D'Ambrosio D, Hippen KL, Minskoff SA, Mellman I, Pani G, Siminovitch KA, Cambier JC. Recruitment and activation of PTP1C in negative regulation of antigen receptor signaling by FcγRIIB1 Science. 268: 293-297. PMID 7716523 DOI: 10.1126/Science.7716523 |
0.515 |
|
1995 |
Pani G, Kozlowski M, Cambier JC, Mills GB, Siminovitch KA. Identification of the tyrosine phosphatase PTP1C as a B cell antigen receptor-associated protein involved in the regulation of B cell signaling. The Journal of Experimental Medicine. 181: 2077-84. PMID 7539038 DOI: 10.1084/Jem.181.6.2077 |
0.571 |
|
1995 |
Valentine MA, Czernik AJ, Rachie N, Hidaka H, Fisher CL, Cambier JC, Bomsztyk K. Anti-immunoglobulin M activates nuclear calcium/calmodulin-dependent protein kinase II in human B lymphocytes. The Journal of Experimental Medicine. 182: 1943-9. PMID 7500040 DOI: 10.1084/Jem.182.6.1943 |
0.406 |
|
1995 |
Kurosaki T, Johnson SA, Pao L, Sada K, Yamamura H, Cambier JC. Role of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signaling. The Journal of Experimental Medicine. 182: 1815-23. PMID 7500027 DOI: 10.1084/Jem.182.6.1815 |
0.472 |
|
1995 |
Cambier J. Introduction: Conserved signaling motifs in antigen and Fc receptors Seminars in Immunology. 7: 1. DOI: 10.1016/1044-5323(95)90001-2 |
0.427 |
|
1994 |
André P, Cambier JC, Wade TK, Raetz T, Wade WF. Distinct structural compartmentalization of the signal transducing functions of major histocompatibility complex class II (Ia) molecules. The Journal of Experimental Medicine. 179: 763-8. PMID 8294884 DOI: 10.1084/Jem.179.2.763 |
0.5 |
|
1994 |
Wade WF, Davoust J, Salamero J, André P, Watts TH, Cambier JC. Structural compartmentalization of MHC class II signaling function. Immunology Today. 14: 539-46. PMID 8274197 DOI: 10.1016/0167-5699(93)90184-M |
0.389 |
|
1994 |
Cambier JC, Jensen WA. The hetero-oligomeric antigen receptor complex and its coupling to cytoplasmic effectors Current Opinion in Genetics and Development. 4: 55-63. PMID 8193541 DOI: 10.1016/0959-437X(94)90091-4 |
0.471 |
|
1994 |
Pleiman CM, Abrams C, Gauen LT, Bedzyk W, Jongstra J, Shaw AS, Cambier JC. Distinct p53/56lyn and p59fyn domains associate with nonphosphorylated and phosphorylated Ig-alpha. Proceedings of the National Academy of Sciences of the United States of America. 91: 4268-72. PMID 8183901 DOI: 10.1073/Pnas.91.10.4268 |
0.409 |
|
1994 |
Pleiman CM, Hertz WM, Cambier JC. Activation of phosphatidylinositol-3' kinase by Src-family kinase SH3 binding to the p85 subunit. Science (New York, N.Y.). 263: 1609-12. PMID 8128248 DOI: 10.1126/Science.8128248 |
0.358 |
|
1994 |
Cambier JC, Pleiman CM, Clark MR. Signal transduction by the B cell antigen receptor and its coreceptors. Annual Review of Immunology. 12: 457-86. PMID 8011288 DOI: 10.1146/Annurev.Iy.12.040194.002325 |
0.525 |
|
1994 |
Pleiman CM, D'Ambrosio D, Cambier JC. The B-cell antigen receptor complex: structure and signal transduction. Immunology Today. 15: 393-9. PMID 7945780 DOI: 10.1016/0167-5699(94)90267-4 |
0.492 |
|
1994 |
Clark M, Johnson S, Cambier J. Analysis of Ig-alpha-tyrosine kinase interaction reveals two levels of binding specificity and tyrosine phosphorylated Ig-alpha stimulation of Fyn activity. The Embo Journal. 13: 1911-1919. DOI: 10.1002/J.1460-2075.1994.Tb06460.X |
0.397 |
|
1993 |
Pleiman CM, Clark MR, Gauen LK, Winitz S, Coggeshall KM, Johnson GL, Shaw AS, Cambier JC. Mapping of sites on the Src family protein tyrosine kinases p55blk, p59fyn, and p56lyn which interact with the effector molecules phospholipase C-gamma 2, microtubule-associated protein kinase, GTPase-activating protein, and phosphatidylinositol 3-kinase. Molecular and Cellular Biology. 13: 5877-87. PMID 8395016 DOI: 10.1128/mcb.13.9.5877-5887.1993 |
0.369 |
|
1993 |
Cambier JC, Bedzyk W, Campbell K, Chien N, Friedrich J, Harwood A, Jensen W, Pleiman C, Clark MR. The B-cell antigen receptor: structure and function of primary, secondary, tertiary and quaternary components. Immunological Reviews. 132: 85-106. PMID 8349299 DOI: 10.1111/J.1600-065X.1993.Tb00838.X |
0.442 |
|
1993 |
Juan M, Vilella R, Mila J, Yagüe J, Miralles A, Campbell KS, Friedrich RJ, Cambier J, Vives J, De Fougerolles AR. CDw50 and ICAM-3: two names for the same molecule. European Journal of Immunology. 23: 1508-12. PMID 8325327 DOI: 10.1002/Eji.1830230717 |
0.364 |
|
1992 |
Kansas GS, Cambier JC, Tedder TF. CD4 binding to major histocompatibility complex class II antigens induces LFA-1-dependent and -independent homotypic adhesion of B lymphocytes. European Journal of Immunology. 22: 147-52. PMID 1730248 DOI: 10.1002/Eji.1830220122 |
0.504 |
|
1992 |
Clark MR, Campbell KS, Kazlauskas A, Johnson SA, Hertz M, Potter TA, Pleiman C, Cambier JC. The B cell antigen receptor complex: association of Ig-alpha and Ig-beta with distinct cytoplasmic effectors. Science (New York, N.Y.). 258: 123-6. PMID 1439759 DOI: 10.1126/Science.1439759 |
0.437 |
|
1992 |
Cambier JC. Signal transduction by T- and B-cell antigen receptors: converging structures and concepts Current Opinion in Immunology. 4: 257-264. PMID 1418703 DOI: 10.1016/0952-7915(92)90074-O |
0.47 |
|
1992 |
Cambier JC, Campbell KS. Membrane immunoglobulin and its accomplices: new lessons from an old receptor. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 6: 3207-17. PMID 1397843 DOI: 10.1096/Fasebj.6.13.1397843 |
0.507 |
|
1992 |
Cambier JC. Signal transduction by T- cell and B-cell antigen receptors: Converging structures and concepts Current Biology. 2: 386. DOI: 10.1016/0960-9822(92)90085-O |
0.508 |
|
1991 |
Cambier JC. Capturing antigen receptor components. Current Biology. 1: 25-27. PMID 15336198 DOI: 10.1016/0960-9822(91)90117-F |
0.52 |
|
1991 |
Campbell KS, Hager EJ, Friedrich RJ, Cambier JC. IgM antigen receptor complex contains phosphoprotein products of B29 and mb-1 genes. Proceedings of the National Academy of Sciences of the United States of America. 88: 3982-6. PMID 2023945 DOI: 10.1073/Pnas.88.9.3982 |
0.461 |
|
1991 |
Blackman MA, Finkel TH, Kappler J, Cambier J, Marrack P. Altered antigen receptor signaling in anergic T cells from self-tolerant T-cell receptor β-chain transgenic mice Proceedings of the National Academy of Sciences of the United States of America. 88: 6682-6686. PMID 1907374 DOI: 10.1073/Pnas.88.15.6682 |
0.459 |
|
1991 |
Reth M, Hombach J, Wienands J, Campbell KS, Chien N, Justement LB, Cambier JC. The B-cell antigen receptor complex Immunology Today. 12: 196-201. PMID 1878135 DOI: 10.1016/0167-5699(91)90053-V |
0.412 |
|
1991 |
Finkel TH, Kubo RT, Cambier JC. T-cell development and transmembrane signaling: changing biological responses through an unchanging receptor Immunology Today. 12: 79-85. PMID 1829360 DOI: 10.1016/0167-5699(91)90162-M |
0.421 |
|
1991 |
Rijkers GT, Griffioen AW, Zegers BJ, Cambier JC. Ligation of membrane immunoglobulin leads to inactivation of the signal-transducing ability of membrane immunoglobulin, CD19, CD21, and B-cell gp95. Proceedings of the National Academy of Sciences of the United States of America. 87: 8766-70. PMID 1701054 DOI: 10.1073/Pnas.87.22.8766 |
0.505 |
|
1991 |
Justement LB, Campbell KS, Chien NC, Cambier JC. Regulation of B cell antigen receptor signal transduction and phosphorylation by CD45 Science. 252: 1839-1842. PMID 1648262 DOI: 10.1126/Science.1648262 |
0.473 |
|
1990 |
Gallagher RB, Cambier JC. Signal transmission pathways and lymphocyte function. Immunology Today. 11: 187-9. PMID 2162179 DOI: 10.1016/0167-5699(90)90078-N |
0.329 |
|
1990 |
Campbell K, Cambier J. B lymphocyte antigen receptors (mIg) are non-covalently associated with a disulfide linked, inducibly phosphorylated glycoprotein complex. The Embo Journal. 9: 441-448. DOI: 10.1002/J.1460-2075.1990.Tb08129.X |
0.478 |
|
1989 |
Cambier J. Lymphocyte subsets and activation. Current Opinion in Immunology. 1: 220-7. PMID 2978539 DOI: 10.1016/0952-7915(88)90005-2 |
0.317 |
|
1989 |
Cambier JC, Lehmann KR. Ia-mediated signal transduction leads to proliferation of primed B lymphocytes. The Journal of Experimental Medicine. 170: 877-86. PMID 2788709 DOI: 10.1084/Jem.170.3.877 |
0.563 |
|
1989 |
Finkel TH, Cambier JC, Kubo RT, Born WK, Marrack P, Kappler JW. The thymus has two functionally distinct populations of immature alpha beta + T cells: one population is deleted by ligation of alpha beta TCR. Cell. 58: 1047-54. PMID 2673539 DOI: 10.1016/0092-8674(89)90503-5 |
0.405 |
|
1989 |
Marrack P, Blackman M, Burgert HG, McCormack JM, Cambier J, Finkel TH, Kappler J. T-cell repertoire and thymus Cold Spring Harbor Symposia On Quantitative Biology. 54: 105-110. PMID 2639749 DOI: 10.1101/Sqb.1989.054.01.013 |
0.338 |
|
1989 |
Chien MM, Cambier JC. Measurement of phosphoinositide hydrolysis in isolated cell membrane preparations Methods in Enzymology. 168: 338-347. PMID 2542728 DOI: 10.1016/0076-6879(89)68024-X |
0.38 |
|
1989 |
Wade WF, Chen ZZ, Maki R, McKercher S, Palmer E, Cambier JC, Freed JH. Altered I-A protein-mediated transmembrane signaling in B cells that express truncated I-Ak protein. Proceedings of the National Academy of Sciences of the United States of America. 86: 6297-301. PMID 2503831 DOI: 10.1073/Pnas.86.16.6297 |
0.46 |
|
1988 |
Caldwell KK, Newell MK, Cambier JC, Prasad KN, Masserano JM, Schlegel W, Cooper DM. Evaluation of methods for the isolation of plasma membranes displaying guanosine 5'-triphosphate-dependence for the regulation of adenylate cyclase activity: potential application to the study of other guanosine 5'-triphosphate-dependent transduction systems. Analytical Biochemistry. 175: 177-90. PMID 3245566 DOI: 10.1016/0003-2697(88)90376-4 |
0.323 |
|
1988 |
Cambier J, Chen ZZ, Pasternak J, Ransom J, Sandoval V, Pickles H. Ligand-induced desensitization of B-cell membrane immunoglobulin-mediated Ca2+ mobilization and protein kinase C translocation Proceedings of the National Academy of Sciences of the United States of America. 85: 6493-6497. PMID 3045817 DOI: 10.1073/Pnas.85.17.6493 |
0.441 |
|
1988 |
Cambier JC, Julius MH. Early changes in quiescent B cell physiology subsequent to cognate and bystander interaction with helper T cells. Scandinavian Journal of Immunology. 27: 59-71. PMID 2963373 DOI: 10.1111/J.1365-3083.1988.Tb02323.X |
0.483 |
|
1987 |
Finkel TH, McDuffie M, Kappler JW, Marrack P, Cambier JC. Both immature and mature T cells mobilize Ca2+ in response to antigen receptor crosslinking Nature. 330: 179-181. PMID 3499573 DOI: 10.1038/330179A0 |
0.445 |
|
1987 |
Julius MH, Paige CJ, Leanderson T, Cambier JC. Neither interleukin 2 nor gamma interferon directly promote growth or differentiation of mouse B cells. Scandinavian Journal of Immunology. 25: 195-202. PMID 3103206 DOI: 10.1111/J.1365-3083.1987.Tb01064.X |
0.405 |
|
1987 |
Cambier JC, Chen ZZ, Ransom JT, Coggeshall KM, Klemsz MJ, Harris LK, Sandoval VM, Newell MK. Differential transmembrane signaling in B lymphocyte activation. Annals of the New York Academy of Sciences. 494: 52-64. PMID 3037967 DOI: 10.1111/J.1749-6632.1987.Tb29481.X |
0.429 |
|
1987 |
Cambier JC, Newell MK, Justement LB, McGuire JC, Leach KL, Chen ZZ. Ia binding ligands and cAMP stimulate nuclear translocation of PKC in B lymphocytes Nature. 327: 629-632. PMID 3037375 |
0.421 |
|
1987 |
Cambier JC, Ransom JT, Harris LK, Coggeshall KM, Chen ZZ, Newell MK, Justement LB. Coupling of B cell surface Ig, Ia and BSF1 receptors to intracellular "second messengers". Advances in Experimental Medicine and Biology. 213: 195-205. PMID 2820209 DOI: 10.1007/978-1-4684-5323-2_19 |
0.48 |
|
1987 |
Cambier JC, Ransom JT. Molecular mechanisms of transmembrane signaling in B lymphocytes Annual Review of Immunology. 5: 175-199. PMID 2439102 DOI: 10.1146/Annurev.Iy.05.040187.001135 |
0.49 |
|
1987 |
Cambier JC, Justement LB, Newell MK, Chen ZZ, Harris LK, Sandoval VM, Klemsz MJ, Ransom JT. Transmembrane signals and intracellular "second messengers" in the regulation of quiescent B-lymphocyte activation Immunological Reviews. 95: 37-57. PMID 2437013 DOI: 10.1111/J.1600-065X.1987.Tb00499.X |
0.446 |
|
1986 |
Cambier JC. Seeing the way to B-cell growth. Nature. 319: 620. PMID 3485253 DOI: 10.1038/319620A0 |
0.39 |
|
1985 |
Cambier JC, Monroe JG, Coggeshall KM, Ransom JT. The biochemical basis of transmembrane signalling by B lymphocyte surface immunoglobulin. Immunology Today. 6: 218-222. PMID 25290184 DOI: 10.1016/0167-5699(85)90038-6 |
0.484 |
|
1985 |
Monroe JG, Cambier JC, Mody EA, Pisetsky DS. Hyper-Ia antigen expression on B cells from B6-lpr/lpr mice correlates with manifestations of the autoimmune state. Clinical Immunology and Immunopathology. 34: 124-9. PMID 3871181 DOI: 10.1016/0090-1229(85)90015-7 |
0.467 |
|
1984 |
Roehm NW, Leibson HJ, Zlotnik A, Kappler J, Marrack P, Cambier JC. Interleukin-induced increase in Ia expression by normal mouse B cells. The Journal of Experimental Medicine. 160: 679-94. PMID 6432933 DOI: 10.1084/Jem.160.3.679 |
0.478 |
|
1984 |
Roehm N, Herron L, Cambier J, Diguisto D, Haskins K, Kappler J, Marrack P. The major histocompatibility complex-restricted antigen receptor on T cells: Distribution on thymus and peripheral T cells Cell. 38: 577-584. PMID 6331891 DOI: 10.1016/0092-8674(84)90512-9 |
0.456 |
|
1983 |
Monroe JG, Cambier JC. Sorting of B lymphoblasts based upon cell diameter provides cell populations enriched in different stages of cell cycle. Journal of Immunological Methods. 63: 45-56. PMID 6604756 DOI: 10.1016/0022-1759(83)90208-9 |
0.396 |
|
1983 |
Monroe JG, Cambier JC. B cell activation. I. Anti-immunoglobulin-induced receptor cross-linking results in a decrease in the plasma membrane potential of murine B lymphocytes. The Journal of Experimental Medicine. 157: 2073-86. PMID 6602204 DOI: 10.1084/Jem.157.6.2073 |
0.472 |
|
1983 |
Monroe JG, Havran WL, Cambier JC. B lymphocyte activation: entry into cell cycle is accompanied by decreased expression of IgD but not IgM. European Journal of Immunology. 13: 208-13. PMID 6601015 DOI: 10.1002/Eji.1830130306 |
0.423 |
|
1983 |
Monroe JG, Cambier JC. B cell activation. III. B cell plasma membrane depolarization and hyper-Ia antigen expression induced by receptor immunoglobulin cross-linking are coupled. The Journal of Experimental Medicine. 158: 1589-99. PMID 6415207 DOI: 10.1084/Jem.158.5.1589 |
0.482 |
|
1982 |
Monroe JG, Cambier JC. Cell cycle dependence for expression of membrane associated IgD, IgM and Ia antigen on mitogen-stimulated murine B-lymphocytes. Annals of the New York Academy of Sciences. 399: 238-54. PMID 6984607 DOI: 10.1111/J.1749-6632.1982.Tb25677.X |
0.43 |
|
1982 |
Cambier JC, Neale MJ. Isolated phosphorylcholine binding lymphocytes. I. Use of a cleavable crosslinking reagent for solid-phase adsorbent isolation of functional antigen binding cells. Journal of Immunological Methods. 51: 209-21. PMID 6809832 DOI: 10.1016/0022-1759(82)90260-5 |
0.396 |
|
1982 |
Cambier JC, Monroe JG, Neale MJ. Definition of conditions that enable antigen-specific activation of the majority of isolated trinitrophenol-binding B cells. The Journal of Experimental Medicine. 156: 1635-49. PMID 6184434 DOI: 10.1084/Jem.156.6.1635 |
0.459 |
|
1982 |
Monroe JG, Havran WL, Cambier JC. Enrichment of viable lymphocytes in defined cycle phases by sorting on the basis of pulse width of axial light extinction. Cytometry. 3: 24-7. PMID 6180872 DOI: 10.1002/Cyto.990030107 |
0.36 |
|
1981 |
Cambier JC, Neale MJ. Induction of clonally restricted thymus-dependent antibody responses in vitro using phosphorylcholine derivatized sheep erythrocytes. Journal of Immunological Methods. 38: 231-8. PMID 7003017 DOI: 10.1016/0022-1759(80)90271-9 |
0.343 |
|
1981 |
Cambier JC, Corley RB. The effect of second signals on the induction of B cell tolerance: Failure of helper T cells to block tolerance induction European Journal of Immunology. 11: 550-556. PMID 6169534 DOI: 10.1002/Eji.1830110706 |
0.477 |
|
1979 |
Kettman JR, Cambier JC, Uhr JW, Ligler F, Vitetta ES. The role of receptor IgM and IgD in determining triggering and induction of tolerance in murine B cells Immunological Reviews. 43: 69-95. PMID 83290 DOI: 10.1111/J.1600-065X.1979.Tb00418.X |
0.497 |
|
1978 |
Cambier JC, Ligler FS, Uhr JW, Kettman JR, Vitetta ES. Blocking of primary in vitro antibody responses to thymus-independent and thymus-dependent antigens with antiserum specific for IgM or IgD Proceedings of the National Academy of Sciences of the United States of America. 75: 432-435. PMID 305047 DOI: 10.1073/Pnas.75.1.432 |
0.378 |
|
1977 |
Vitetta ES, Cambier JC, Ligler FS, Kettman JR, Uhr JW. B-cell tolerance. IV. Differential role of surface IgM and IgD in determining tolerance susceptibility of murine B cells Journal of Experimental Medicine. 146: 1804-1808. PMID 303688 DOI: 10.1084/Jem.146.6.1804 |
0.427 |
|
1977 |
Cambier JC, Vitetta ES, Uhr JW, Kettman JR. B cell tolerance. II. Trinitrophenyl human gamma globulin induced tolerance in adult and neonatal murine B cells responsive to thymus dependent and independent forms of the same hapten Journal of Experimental Medicine. 145: 778-783. PMID 95788 DOI: 10.1084/Jem.145.3.778 |
0.443 |
|
1977 |
Cambier JC, Vitetta ES, Kettman JR, Wetzel GM, Uhr JW. B-cell tolerance. III. Effect of papain-mediated cleavage of cell surface IgD on tolerance susceptibility of murine B cells Journal of Experimental Medicine. 146: 107-117. PMID 68987 DOI: 10.1084/Jem.146.1.107 |
0.48 |
|
1976 |
Cambier JC, Kettman JR, Vitetta ES, Uhr JW. Differential susceptibility of neonatal and adult murine spleen cells to in vitro induction of B cell tolerance Journal of Experimental Medicine. 144: 293-297. PMID 1084409 DOI: 10.1084/Jem.144.1.293 |
0.439 |
|
1976 |
Vitetta ES, Cambier J, Forman J, Kettman JR, Yuan D, Uhr JW. Immunoglobulin receptors on murine B lymphocytes Origins of Lymphocyte Diversity Cold Spring Harbor Symposia On Quantitative Biology. 41: 185-191. PMID 302188 DOI: 10.1101/Sqb.1977.041.01.024 |
0.474 |
|
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