David R. Soto-Pantoja, Ph.D. - Publications

Affiliations: 
2008 Wake Forest University, Winston-Salem, NC, United States 
Area:
Oncology, Cell Biology, Molecular Biology

57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Mackert JD, Stirling ER, Wilson AS, Westwood B, Zhao D, Lo HW, Metheny-Barlow L, Cook KL, Lesser GJ, Soto-Pantoja DR. Anti-CD47 immunotherapy as a therapeutic strategy for the treatment of breast cancer brain metastasis. Biorxiv : the Preprint Server For Biology. PMID 37546807 DOI: 10.1101/2023.07.25.550566  0.641
2023 Klepin HD, Tooze JA, Bitting RL, Davis B, Pleasant K, Melo AC, Cook K, Soto-Pantoja DR, Tallant EA, Gallagher PE. Study design and methods for the pilot study of muscadine grape extract supplement to improve fatigue among older adult cancer survivors (FOCUS) trial. Journal of Geriatric Oncology. 101478. PMID 36990930 DOI: 10.1016/j.jgo.2023.101478  0.664
2022 Bronson SM, Westwood B, Cook KL, Emenaker NJ, Chappell MC, Roberts DD, Soto-Pantoja DR. Discrete Correlation Summation Clustering Reveals Differential Regulation of Liver Metabolism by Thrombospondin-1 in Low-Fat and High-Fat Diet-Fed Mice. Metabolites. 12. PMID 36355119 DOI: 10.3390/metabo12111036  0.535
2022 Bawaneh A, Wilson AS, Levi N, Howard-McNatt MM, Chiba A, Soto-Pantoja DR, Cook KL. Intestinal Microbiota Influence Doxorubicin Responsiveness in Triple-Negative Breast Cancer. Cancers. 14. PMID 36230772 DOI: 10.3390/cancers14194849  0.618
2022 Newman TM, Clear KYJ, Wilson AS, Soto-Pantoja DR, Ochs-Balcom HM, Cook KL. Early life dietary exposures mediate persistent shifts in the gut microbiome and visceral fat metabolism. American Journal of Physiology. Cell Physiology. PMID 35848617 DOI: 10.1152/ajpcell.00380.2021  0.518
2022 Shelkey E, Oommen D, Stirling ER, Soto-Pantoja DR, Cook KL, Lu Y, Votanopoulos KI, Soker S. Immuno-reactive cancer organoid model to assess effects of the microbiome on cancer immunotherapy. Scientific Reports. 12: 9983. PMID 35705580 DOI: 10.1038/s41598-022-13930-7  0.644
2022 Ramirez MU, Clear KYJ, Cornelius Z, Bawaneh A, Feliz-Mosquea YR, Wilson AS, Ruggiero AD, Cruz-Diaz N, Shi L, Kerr BA, Soto-Pantoja DR, Cook KL. Diet impacts triple-negative breast cancer growth, metastatic potential, chemotherapy responsiveness, and doxorubicin-mediated cardiac dysfunction. Physiological Reports. 10: e15192. PMID 35439354 DOI: 10.14814/phy2.15192  0.584
2022 Triozzi PL, Stirling ER, Song Q, Westwood B, Kooshki M, Forbes ME, Holbrook BC, Cook KL, Alexander-Miller MA, Miller LD, Zhang W, Soto-Pantoja DR. Circulating Immune Bioenergetic, Metabolic, and Genetic Signatures Predict Melanoma Patients' Response to Anti-PD-1 Immune Checkpoint Blockade. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 28: 1192-1202. PMID 35284940 DOI: 10.1158/1078-0432.CCR-21-3114  0.561
2022 Stirling ER, Bronson SM, Mackert JD, Cook KL, Triozzi PL, Soto-Pantoja DR. Metabolic Implications of Immune Checkpoint Proteins in Cancer. Cells. 11. PMID 35011741 DOI: 10.3390/cells11010179  0.6
2021 Arnone AA, Cline JM, Soto-Pantoja DR, Cook KL. Investigating the role of endogenous estrogens, hormone replacement therapy, and blockade of estrogen receptor-α activity on breast metabolic signaling. Breast Cancer Research and Treatment. PMID 34448090 DOI: 10.1007/s10549-021-06354-w  0.575
2021 Soto-Pantoja DR, Gaber M, Arnone AA, Bronson SM, Cruz-Diaz N, Wilson AS, Clear KYJ, Ramirez MU, Kucera GL, Levine EA, Lelievre SA, Chaboub L, Chiba A, Yadav H, Vidi PA, et al. Diet alters entero-mammary signaling to regulate the breast microbiome and tumorigenesis. Cancer Research. PMID 34083249 DOI: 10.1158/0008-5472.CAN-20-2983  0.616
2021 Kaur S, Bronson SM, Pal-Nath D, Miller TW, Soto-Pantoja DR, Roberts DD. Functions of Thrombospondin-1 in the Tumor Microenvironment. International Journal of Molecular Sciences. 22. PMID 33925464 DOI: 10.3390/ijms22094570  0.354
2020 Crofts KF, Holbrook BC, Soto-Pantoja DR, Ornelles DA, Alexander-Miller MA. TCR Dependent Metabolic Programming Regulates Autocrine IL-4 Production Resulting in Self-Tuning of the CD8 T Cell Activation Setpoint. Frontiers in Immunology. 11: 540. PMID 32300344 DOI: 10.3389/Fimmu.2020.00540  0.339
2020 Soto-Pantoja D, Clear K, Cook KL. Abstract P5-14-19: Targeting the unfolded protein response components differentially sensitizes breast tumors to doxorubicin while modulating chemotherapy-induced cardiotoxicities Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P5-14-19  0.676
2019 Ramirez MU, Hernandez SR, Soto-Pantoja DR, Cook KL. Endoplasmic Reticulum Stress Pathway, the Unfolded Protein Response, Modulates Immune Function in the Tumor Microenvironment to Impact Tumor Progression and Therapeutic Response. International Journal of Molecular Sciences. 21. PMID 31881743 DOI: 10.3390/Ijms21010169  0.652
2019 Kaur S, Schwartz AL, Jordan DG, Soto-Pantoja DR, Kuo B, Elkahloun AG, Mathews Griner L, Thomas CJ, Ferrer M, Thomas A, Tang SW, Rajapakse VN, Pommier Y, Roberts DD. Identification of Schlafen-11 as a Target of CD47 Signaling That Regulates Sensitivity to Ionizing Radiation and Topoisomerase Inhibitors. Frontiers in Oncology. 9: 994. PMID 31632920 DOI: 10.3389/Fonc.2019.00994  0.397
2019 Chiba A, Bawaneh A, Velazquez C, Clear KY, Wilson AS, Howard-McNatt M, Levine E, Levi-Polyachenko N, Yates-Alston SA, Diggle S, Soto-Pantoja DR, Cook KL. Neoadjuvant chemotherapy shifts breast tumor microbiota populations to regulate drug responsiveness and the development of metastasis. Molecular Cancer Research : McR. PMID 31628201 DOI: 10.1158/1541-7786.Mcr-19-0451  0.648
2019 Stirling ER, Cook KL, Roberts DD, Soto-Pantoja DR. Metabolomic Analysis Reveals Unique Biochemical Signatures Associated with Protection from Radiation Induced Lung Injury by Lack of Receptor Gene Expression. Metabolites. 9. PMID 31597291 DOI: 10.3390/Metabo9100218  0.612
2019 McGee HM, Jiang D, Soto-Pantoja DR, Nevler A, Giaccia AJ, Woodward WA. Targeting the Tumor Microenvironment in Radiation Oncology: Proceedings from the 2018 ASTRO-AACR Research Workshop. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30723144 DOI: 10.1158/1078-0432.Ccr-18-3781  0.397
2018 Wärri A, Cook KL, Hu R, Jin L, Zwart A, Soto-Pantoja DR, Liu J, Finkel T, Clarke R. Autophagy and unfolded protein response (UPR) regulate mammary gland involution by restraining apoptosis-driven irreversible changes. Cell Death Discovery. 5: 40. PMID 30345078 DOI: 10.1038/S41420-018-0105-Y  0.629
2018 Feliz-Mosquea YR, Christensen AA, Wilson AS, Westwood B, Varagic J, Meléndez GC, Schwartz AL, Chen QR, Mathews Griner L, Guha R, Thomas CJ, Ferrer M, Merino MJ, Cook KL, Roberts DD, ... Soto-Pantoja DR, et al. Combination of anthracyclines and anti-CD47 therapy inhibit invasive breast cancer growth while preventing cardiac toxicity by regulation of autophagy. Breast Cancer Research and Treatment. PMID 30056566 DOI: 10.1007/S10549-018-4884-X  0.676
2018 Ramirez MU, Stirling ER, Emenaker NJ, Roberts DD, Soto-Pantoja DR. Thrombospondin-1 interactions regulate eicosanoid metabolism and signaling in cancer-related inflammation. Cancer Metastasis Reviews. PMID 29909440 DOI: 10.1007/S10555-018-9737-X  0.421
2018 Abunimer AN, Mohammed H, Cook KL, Soto-Pantoja DR, Campos MM, Abu-Asab MS. Mitochondrial autophagosomes as a mechanism of drug resistance in breast carcinoma. Ultrastructural Pathology. 1-11. PMID 29419344 DOI: 10.1080/01913123.2017.1419328  0.614
2018 Soto-Pantoja DR, Feliz-Mosquea YR, Clear KY, Wilson AS, Cook KL. Abstract 449: Targeting PKR-like endoplasmic reticulum kinase modulates metabolism to promote T-cell effector function and PD1 immunotherapy responsiveness Cancer Research. 78: 449-449. DOI: 10.1158/1538-7445.Am2018-449  0.646
2018 Feliz-Mosquea YR, Stirling E, Cook KL, Wilson A, Bharadwaj M, Molina AJ, Yamaleyeva L, Triozzi PL, Soto-Pantoja DR. Abstract 3528: Anti-CD47 immunotherapy regulates T cell metabolism and hypoxia in the tumor microenvironment Cancer Research. 78: 3528-3528. DOI: 10.1158/1538-7445.Am2018-3528  0.653
2017 Soto-Pantoja DR, Wilson AS, Clear KY, Westwood B, Triozzi PL, Cook KL. Unfolded protein response signaling impacts macrophage polarity to modulate breast cancer cell clearance and melanoma immune checkpoint therapy responsiveness. Oncotarget. 8: 80545-80559. PMID 29113324 DOI: 10.18632/Oncotarget.19849  0.675
2017 Cook KL, Soto-Pantoja DR. "UPRegulation" of CD47 by the endoplasmic reticulum stress pathway controls anti-tumor immune responses. Biomarker Research. 5: 26. PMID 28815041 DOI: 10.1186/S40364-017-0105-8  0.68
2017 Soto-Pantoja DR, Sipes JM, Westwood B, Morris N, Emenaker NJ, Roberts DD. Abstract LB-213: Thrombospondin-1 regulates intestinal microbiota and bile acid metabolism in a murine model of colorectal cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Lb-213  0.341
2017 Smith AA, Wilson AS, Soto-Pantoja DR. Abstract 5661: Targeting CD47 expression on macrophages regulates immunometabolism enhancing tumoricidal activity against cancer cells Cancer Research. 77: 5661-5661. DOI: 10.1158/1538-7445.Am2017-5661  0.45
2016 Cook KL, Soto-Pantoja DR, Clarke PA, Cruz MI, Zwart A, Wärri A, Hilakivi-Clarke L, Roberts DD, Clarke R. Endoplasmic Reticulum Stress Protein GRP78 Modulates Lipid Metabolism to Control Drug Sensitivity and Antitumor Immunity in Breast Cancer. Cancer Research. 76: 5657-5670. PMID 27698188 DOI: 10.1158/0008-5472.Can-15-2616  0.655
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin J, Abeliovich H, Arozena AA, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Soto-Pantoja DR, et al. Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 Autophagy. 12: 443-443. PMID 26902590 DOI: 10.1080/15548627.2016.1147886  0.536
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Soto-Pantoja DR, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.579
2016 Roberts DD, Smith A, Sipes JM, Wilson A, Mathews-Griner L, Guha R, Thomas CJ, Ferrer M, Soto-Pantoja DR. Abstract 1352: High-throughput matrix screening reveals synergistic chemotherapeutic combinations with blockade of CD47 to enhance cytotoxicity in breast cancer Cancer Research. 76: 1352-1352. DOI: 10.1158/1538-7445.Am2016-1352  0.45
2015 Miller TW, Soto-Pantoja DR, Schwartz AL, Sipes JM, DeGraff WG, Ridnour LA, Wink DA, Roberts DD. CD47 Globally Regulates Metabolic Pathways that Control Resistance to Ionizing Radiation. The Journal of Biological Chemistry. PMID 26311851 DOI: 10.1074/Jbc.M115.665752  0.398
2015 Ridnour LA, Cheng RY, Weiss JM, Kaur S, Soto-Pantoja DR, Basudhar D, Heinecke JL, Stewart CA, DeGraff W, Sowers AL, Thetford A, Kesarwala AH, Roberts DD, Young HA, Mitchell JB, et al. NOS Inhibition Modulates Immune Polarization and Improves Radiation-Induced Tumor Growth Delay. Cancer Research. 75: 2788-99. PMID 25990221 DOI: 10.1158/0008-5472.Can-14-3011  0.364
2015 Roberts DD, Kaur S, Soto-Pantoja DR. Therapeutic targeting of the thrombospondin-1 receptor CD47 to treat liver cancer. Journal of Cell Communication and Signaling. 9: 101-2. PMID 25779848 DOI: 10.1007/S12079-015-0283-9  0.419
2015 Soto-Pantoja DR, Kaur S, Roberts DD. CD47 signaling pathways controlling cellular differentiation and responses to stress. Critical Reviews in Biochemistry and Molecular Biology. 1-19. PMID 25708195 DOI: 10.3109/10409238.2015.1014024  0.367
2015 Soto-Pantoja DR, Sipes JM, Morris N, Emmenaker NJ, Roberts DD. Abstract 1202: Thrombospondin-1 regulates energy metabolism to increase carcinogenesis in an in vivo model of colorectal cancer Cancer Research. 75: 1202-1202. DOI: 10.1158/1538-7445.Am2015-1202  0.378
2014 Cook KL, Soto-Pantoja DR, Jin L, Abu-Asab M, Clarke R. When is a vesicle not just a vesicle: mitochondrial spheroids and mitochondrial autophagosomes. Cell & Bioscience. 4: 66. PMID 25699171 DOI: 10.1186/2045-3701-4-66  0.581
2014 Soto-Pantoja DR, Terabe M, Ghosh A, Ridnour LA, DeGraff WG, Wink DA, Berzofsky JA, Roberts DD. CD47 in the tumor microenvironment limits cooperation between antitumor T-cell immunity and radiotherapy. Cancer Research. 74: 6771-83. PMID 25297630 DOI: 10.1158/0008-5472.Can-14-0037-T  0.399
2014 Kaur S, Chang T, Singh SP, Lim L, Mannan P, Garfield SH, Pendrak ML, Soto-Pantoja DR, Rosenberg AZ, Jin S, Roberts DD. CD47 signaling regulates the immunosuppressive activity of VEGF in T cells. Journal of Immunology (Baltimore, Md. : 1950). 193: 3914-24. PMID 25200950 DOI: 10.4049/Jimmunol.1303116  0.348
2014 Cook KL, Wärri A, Soto-Pantoja DR, Clarke PA, Cruz MI, Zwart A, Clarke R. Hydroxychloroquine inhibits autophagy to potentiate antiestrogen responsiveness in ER+ breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 3222-32. PMID 24928945 DOI: 10.1158/1078-0432.Ccr-13-3227  0.622
2014 Soto-Pantoja DR, Shih HB, Maxhimer JB, Cook KL, Ghosh A, Isenberg JS, Roberts DD. Thrombospondin-1 and CD47 signaling regulate healing of thermal injury in mice. Matrix Biology : Journal of the International Society For Matrix Biology. 37: 25-34. PMID 24840925 DOI: 10.1016/J.Matbio.2014.05.003  0.595
2014 Cook KL, Soto-Pantoja DR, Abu-Asab M, Clarke PA, Roberts DD, Clarke R. Mitochondria directly donate their membrane to form autophagosomes during a novel mechanism of parkin-associated mitophagy. Cell & Bioscience. 4: 16. PMID 24669863 DOI: 10.1186/2045-3701-4-16  0.543
2014 Soto-Pantoja DR, Sipes JM, Ghosh A, Merino MJ, Roberts DD. Abstract 2434: Therapeutic targeting of CD47 regulates cell bioenergetics and autophagy to reduce breast tumor growth and protect against anthracycline-mediated cardiac toxicity Cancer Research. 74: 2434-2434. DOI: 10.1158/1538-7445.Am2014-2434  0.489
2013 Kaur S, Soto-Pantoja DR, Stein EV, Liu C, Elkahloun AG, Pendrak ML, Nicolae A, Singh SP, Nie Z, Levens D, Isenberg JS, Roberts DD. Thrombospondin-1 signaling through CD47 inhibits self-renewal by regulating c-Myc and other stem cell transcription factors. Scientific Reports. 3: 1673. PMID 23591719 DOI: 10.1038/Srep01673  0.346
2013 Soto-Pantoja DR, Ridnour LA, Wink DA, Roberts DD. Blockade of CD47 increases survival of mice exposed to lethal total body irradiation. Scientific Reports. 3: 1038. PMID 23301159 DOI: 10.1038/Srep01038  0.373
2013 Soto-Pantoja DR, Stein EV, Rogers NM, Sharifi-Sanjani M, Isenberg JS, Roberts DD. Therapeutic opportunities for targeting the ubiquitous cell surface receptor CD47. Expert Opinion On Therapeutic Targets. 17: 89-103. PMID 23101472 DOI: 10.1517/14728222.2013.733699  0.342
2013 Gallagher PE, Arter AL, Soto-Pantoja DR, Tallant EA. Abstract C66: Angiotensin-(1-7) attenuates triple-negative breast cancer growth and progression through regulation of protein phosphatases Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-C66  0.666
2012 Martin-Manso G, Navarathna DH, Galli S, Soto-Pantoja DR, Kuznetsova SA, Tsokos M, Roberts DD. Endogenous thrombospondin-1 regulates leukocyte recruitment and activation and accelerates death from systemic candidiasis. Plos One. 7: e48775. PMID 23144964 DOI: 10.1371/Journal.Pone.0048775  0.322
2012 Soto-Pantoja DR, Miller TW, Frazier WA, Roberts DD. Inhibitory signaling through signal regulatory protein-α is not sufficient to explain the antitumor activities of CD47 antibodies. Proceedings of the National Academy of Sciences of the United States of America. 109: E2842; author reply . PMID 22923696 DOI: 10.1073/Pnas.1205441109  0.35
2012 Soto-Pantoja DR, Miller TW, Pendrak ML, DeGraff WG, Sullivan C, Ridnour LA, Abu-Asab M, Wink DA, Tsokos M, Roberts DD. CD47 deficiency confers cell and tissue radioprotection by activation of autophagy. Autophagy. 8: 1628-42. PMID 22874555 DOI: 10.4161/Auto.21562  0.382
2011 Soto-Pantoja DR, Isenberg JS, Roberts DD. Therapeutic Targeting of CD47 to Modulate Tissue Responses to Ischemia and Radiation. Journal of Genetic Syndromes & Gene Therapy. 2. PMID 22685691 DOI: 10.4172/2157-7412.1000105  0.391
2011 Gallagher PE, Cook K, Soto-Pantoja D, Menon J, Tallant EA. Angiotensin peptides and lung cancer. Current Cancer Drug Targets. 11: 394-404. PMID 21395552 DOI: 10.2174/156800911795538048  0.701
2009 Maxhimer JB, Soto-Pantoja DR, Ridnour LA, Shih HB, Degraff WG, Tsokos M, Wink DA, Isenberg JS, Roberts DD. Radioprotection in normal tissue and delayed tumor growth by blockade of CD47 signaling. Science Translational Medicine. 1: 3ra7. PMID 20161613 DOI: 10.1126/Scitranslmed.3000139  0.399
2009 Soto-Pantoja DR, Menon J, Gallagher PE, Tallant EA. Angiotensin-(1-7) inhibits tumor angiogenesis in human lung cancer xenografts with a reduction in vascular endothelial growth factor. Molecular Cancer Therapeutics. 8: 1676-83. PMID 19509262 DOI: 10.1158/1535-7163.Mct-09-0161  0.623
2007 Menon J, Soto-Pantoja DR, Callahan MF, Cline JM, Ferrario CM, Tallant EA, Gallagher PE. Angiotensin-(1-7) inhibits growth of human lung adenocarcinoma xenografts in nude mice through a reduction in cyclooxygenase-2. Cancer Research. 67: 2809-15. PMID 17363603 DOI: 10.1158/0008-5472.Can-06-3614  0.634
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