David Owen Bates - Publications

University of Nottingham, Nottingham, England, United Kingdom 
Microcirculation, vascular biology, angiogeneiss, vascuar permeability

139 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Machado MJC, Boardman R, Riu F, Emanueli C, Benest AV, Bates DO. Enhanced Notch signaling modulates unproductive revascularization in response to Nitric Oxide-Angiopoietin signaling in a mouse model of peripheral ischemia. Microcirculation (New York, N.Y. : 1994). e12549. PMID 30974486 DOI: 10.1111/micc.12549  1
2019 Boardman R, Pang V, Malhi N, Lynch AP, Leach L, Benest AV, Bates DO, Machado MJ. Activation of Notch signalling by soluble Dll4 decreases vascular permeability via a cAMP/PKA-dependent pathway. American Journal of Physiology. Heart and Circulatory Physiology. PMID 30681366 DOI: 10.1152/ajpheart.00610.2018  1
2018 Tzelepis K, De Braekeleer E, Aspris D, Barbieri I, Vijayabaskar MS, Liu WH, Gozdecka M, Metzakopian E, Toop HD, Dudek M, Robson SC, Hermida-Prado F, Yang YH, Babaei-Jadidi R, Garyfallos DA, ... ... Bates DO, et al. SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4. Nature Communications. 9: 5378. PMID 30568163 DOI: 10.1038/s41467-018-07620-0  0.32
2018 Onions K, Gamez M, Buckner NR, Baker SL, Betteridge KB, Desideri S, Dallyn BP, Ramnath R, Neal CR, Farmer LK, Mathieson PW, Gnudi L, Alitalo K, Bates DO, Salmon AHJ, et al. VEGFC Reduces Glomerular Albumin Permeability and Protects Against Alterations in VEGF Receptor Expression in Diabetic Nephropathy. Diabetes. PMID 30389746 DOI: 10.2337/db18-0045  0.8
2018 Neal CR, Arkill KP, Bell JS, Betteridge KB, Bates DO, Winlove CP, Salmon AHJ, Harper SJ. Novel hemodynamic structures in the human glomerulus. American Journal of Physiology. Renal Physiology. 315: F1370-F1384. PMID 30388047 DOI: 10.1152/ajprenal.00566.2017  1
2018 Descamps B, Saif J, Benest AV, Biglino G, Bates DO, Chamorro-Jorganes A, Emanueli C. BDNF (Brain-Derived Neurotrophic Factor) Promotes Embryonic Stem Cells Differentiation to Endothelial Cells Via a Molecular Pathway, Including MicroRNA-214, EZH2 (Enhancer of Zeste Homolog 2), and eNOS (Endothelial Nitric Oxide Synthase). Arteriosclerosis, Thrombosis, and Vascular Biology. 38: 2117-2125. PMID 30354255 DOI: 10.1161/ATVBAHA.118.311400  1
2018 Bates DO, Beazley-Long N, Benest AV, Ye X, Ved N, Hulse RP, Barratt S, Machado MJ, Donaldson LF, Harper SJ, Peiris-Pages M, Tortonese DJ, Oltean S, Foster RR. Physiological Role of Vascular Endothelial Growth Factors as Homeostatic Regulators. Comprehensive Physiology. 8: 955-979. PMID 29978898 DOI: 10.1002/cphy.c170015  1
2018 Bestall SM, Hulse RP, Blackley Z, Swift M, Ved N, Paton K, Beazley-Long N, Bates DO, Donaldson LF. Sensory neuronal sensitisation occurs through HMGB-1/ RAGE and TRPV1 in high glucose conditions. Journal of Cell Science. PMID 29930087 DOI: 10.1242/jcs.215939  0.84
2018 Neal CR, Arkill K, Bell JS, Betteridge KB, Bates DO, Winlove CP, Salmon AH, Harper SJ. NOVEL HAEMODYNAMIC STRUCTURES IN THE HUMAN GLOMERULUS. American Journal of Physiology. Renal Physiology. PMID 29923763 DOI: 10.1152/ajprenal.00566.2017  1
2018 Nowak-Sliwinska P, Alitalo K, Allen E, Anisimov A, Aplin AC, Auerbach R, Augustin HG, Bates DO, van Beijnum JR, Bender RHF, Bergers G, Bikfalvi A, Bischoff J, Böck BC, Brooks PC, et al. Consensus guidelines for the use and interpretation of angiogenesis assays. Angiogenesis. PMID 29766399 DOI: 10.1007/s10456-018-9613-x  0.72
2018 Stevens M, Neal CR, Salmon AHJ, Bates DO, Harper SJ, Oltean S. Vascular Endothelial Growth Factor-A165b Restores Normal Glomerular Water Permeability in a Diphtheria-Toxin Mouse Model of Glomerular Injury. Nephron. PMID 29393270 DOI: 10.1159/000485664  1
2018 Barratt SL, Blythe T, Ourradi K, Jarrett C, Welsh GI, Bates DO, Millar AB. Effects of hypoxia and hyperoxia on the differential expression of VEGF-A isoforms and receptors in Idiopathic Pulmonary Fibrosis (IPF). Respiratory Research. 19: 9. PMID 29334947 DOI: 10.1186/s12931-017-0711-x  0.4
2017 Sae-Lao T, Luplertlop N, Janvilisri T, Tohtong R, Bates DO, Wongprasert K. Sulfated galactans from the red seaweed Gracilaria fisheri exerts anti-migration effect on cholangiocarcinoma cells. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 36: 59-67. PMID 29157829 DOI: 10.1016/j.phymed.2017.09.014  0.72
2017 Barratt SL, Blythe T, Jarrett C, Ourradi K, Shelley-Fraser G, Day MJ, Qiu Y, Harper S, Maher TM, Oltean S, Hames TJ, Scotton CJ, Welsh GI, Bates DO, Millar AB. Differential Expression of VEGF-Axxx Isoforms is Critical for Development of Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. PMID 28661183 DOI: 10.1164/rccm.201603-0568OC  0.72
2017 Mortara L, Benest AV, Bates DO, Noonan DM. Can the co-dependence of the immune system and angiogenesis facilitate pharmacological targeting of tumours? Current Opinion in Pharmacology. 35: 66-74. PMID 28623714 DOI: 10.1016/j.coph.2017.05.009  1
2017 Stevens M, Neal CR, Salmon AH, Bates DO, Harper SJ, Oltean S. VEGF-A165 b protects against proteinuria in a mouse model with progressive depletion of all endogenous VEGF-A splice isoforms from the kidney. The Journal of Physiology. PMID 28574576 DOI: 10.1113/JP274481  1
2017 Betteridge K, Arkill K, Neal C, Harper S, Foster B, Satchell S, Bates D, Salmon A. Sialic acids regulate microvessel permeability, revealed by novel in vivo studies of endothelial glycocalyx structure and function. The Journal of Physiology. PMID 28524373 DOI: 10.1113/JP274167  0.44
2017 Vieira GC, Chockalingam S, Melegh Z, Greenhough A, Malik S, Szemes M, Park JH, Kaidi A, Zhou L, Catchpoole D, Morgan R, Bates DO, Gabb PJ, Malik K. Correction: LGR5 regulates pro-survival MEK/ERK and proliferative Wnt/β-catenin signalling in neuroblastoma. Oncotarget. 8: 32381. PMID 28499332 DOI: 10.18632/oncotarget.17685  0.44
2017 Sae-Lao T, Tohtong R, Bates DO, Wongprasert K. Sulfated Galactans from Red Seaweed Gracilaria fisheri Target EGFR and Inhibit Cholangiocarcinoma Cell Proliferation. The American Journal of Chinese Medicine. 1-19. PMID 28385079 DOI: 10.1142/S0192415X17500367  0.72
2017 Ved N, Hulse RP, Bestall SM, Donaldson LF, Bainbridge JW, Bates D. Vascular endothelial growth factor-A165b ameliorates outer-retinal barrier and vascular dysfunction in the diabetic retina. Clinical Science (London, England : 1979). PMID 28341661 DOI: 10.1042/CS20170102  0.84
2017 Castle-Miller J, Bates DO, Tortonese DJ. Mechanisms regulating angiogenesis underlie seasonal control of pituitary function. Proceedings of the National Academy of Sciences of the United States of America. PMID 28270617 DOI: 10.1073/pnas.1618917114  1
2017 Batson J, Toop HD, Redondo C, Babaei-Jadidi R, Chaikuad A, Wearmouth SF, Gibbons B, Allen C, Tallant C, Zhang J, Du C, Hancox J, Hawtrey T, Da Rocha J, Griffith R, ... ... Bates DO, et al. Development of potent, selective SRPK1 inhibitors as potential topical therapeutics for neovascular eye disease. Acs Chemical Biology. PMID 28135068 DOI: 10.1021/acschembio.6b01048  0.36
2017 Bates DO, Morris JC, Oltean S, Donaldson LF. Pharmacology of Modulators of Alternative Splicing. Pharmacological Reviews. 69: 63-79. PMID 28034912 DOI: 10.1124/pr.115.011239  0.84
2016 Stone OA, Carter JG, Lin PC, Paleolog E, Machado MJ, Bates DO. Differential regulation of blood flow induced neovascularisation and mural cell recruitment by VEGF and angiopoietin signalling. The Journal of Physiology. PMID 27868196 DOI: 10.1113/JP273430  0.72
2016 Hulse RP, Drake RA, Bates DO, Donaldson LF. The control of alternative splicing by SRSF1 in myelinated afferents contributes to the development of neuropathic pain. Neurobiology of Disease. PMID 27616424 DOI: 10.1016/j.nbd.2016.09.009  1
2016 Benest AV, Bates DO. Measurement of Angiogenesis, Arteriolargenesis, and Lymphangiogenesis Phenotypes by Use of Two-Dimensional Mesenteric Angiogenesis Assay. Methods in Molecular Biology (Clifton, N.J.). 1430: 345-54. PMID 27172966 DOI: 10.1007/978-1-4939-3628-1_24  0.84
2016 Gammons MV, Bates DO. Models of Oxygen Induced Retinopathy in Rodents. Methods in Molecular Biology (Clifton, N.J.). 1430: 317-32. PMID 27172964 DOI: 10.1007/978-1-4939-3628-1_22  1
2016 Ye X, Abou-Rayyah Y, Bischoff J, Ritchie A, Sebire NJ, Watts P, Churchill AJ, Bates DO. Altered ratios of pro- and anti-angiogenic VEGF-A variants and pericyte expression of DLL4 disrupt the vascular maturation in infantile haemangioma. The Journal of Pathology. PMID 26957058 DOI: 10.1002/path.4715  1
2015 Lobo DP, Wemyss AM, Smith DJ, Straube A, Betteridge KB, Salmon AH, Foster RR, Elhegni HE, Satchell SC, Little HA, Pacheco-Gómez R, Simmons MJ, Hicks MR, Bates DO, Rodger A, et al. Direct detection and measurement of wall shear stress using a filamentous bio-nanoparticle. Nano Research. 8: 3307-3315. PMID 27570611 DOI: 10.1007/s12274-015-0831-x  0.76
2015 Vieira GC, Chockalingam S, Melegh Z, Greenhough A, Malik S, Szemes M, Park JH, Kaidi A, Zhou L, Catchpoole D, Morgan R, Bates DO, Gabb PD, Malik K. LGR5 regulates pro-survival MEK/ERK and proliferative Wnt/β-catenin signalling in neuroblastoma. Oncotarget. PMID 26517508 DOI: 10.18632/oncotarget.5548  0.52
2015 Bunni J, Shelley-Fraser G, Stevenson K, Oltean S, Salmon A, Harper SJ, Carter JG, Bates DO. Circulating levels of anti-angiogenic VEGF-A isoform (VEGF-Axxxb) in colorectal cancer patients predicts tumour VEGF-A ratios. American Journal of Cancer Research. 5: 2083-9. PMID 26269767  1
2015 Hulse RP, Beazley-Long N, Ved N, Bestall SM, Riaz H, Singhal P, Ballmer Hofer K, Harper SJ, Bates DO, Donaldson LF. Vascular endothelial growth factor-A165b prevents diabetic neuropathic pain and sensory neuronal degeneration. Clinical Science (London, England : 1979). 129: 741-56. PMID 26201024 DOI: 10.1042/CS20150124  1
2015 Wu WK, Georgiadis A, Copland DA, Liyanage S, Luhmann UF, Robbie SJ, Liu J, Wu J, Bainbridge JW, Bates DO, Ali RR, Nicholson LB, Dick AD. IL-4 regulates specific Arg-1(+) macrophage sFlt-1-mediated inhibition of angiogenesis. The American Journal of Pathology. 185: 2324-35. PMID 26079814 DOI: 10.1016/j.ajpath.2015.04.013  1
2015 de Brot S, Ntekim A, Cardenas R, James V, Allegrucci C, Heery DM, Bates DO, Ødum N, Persson JL, Mongan NP. Regulation of vascular endothelial growth factor in prostate cancer. Endocrine-Related Cancer. 22: R107-23. PMID 25870249 DOI: 10.1530/ERC-15-0123  1
2015 Beazley-Long N, Gaston K, Harper SJ, Orlando A, Bates DO. Novel mechanisms of resistance to vemurafenib in melanoma - V600E B-Raf reversion and switching VEGF-A splice isoform expression. American Journal of Cancer Research. 5: 433-41. PMID 25628951  1
2015 Carter JG, Gammons MV, Damodaran G, Churchill AJ, Harper SJ, Bates DO. The carboxyl terminus of VEGF-A is a potential target for anti-angiogenic therapy. Angiogenesis. 18: 23-30. PMID 25274272 DOI: 10.1007/s10456-014-9444-3  1
2015 Hamdollah Zadeh MA, Amin EM, Hoareau-Aveilla C, Domingo E, Symonds KE, Ye X, Heesom KJ, Salmon A, D'Silva O, Betteridge KB, Williams AC, Kerr DJ, Salmon AH, Oltean S, Midgley RS, ... ... Bates DO, et al. Alternative splicing of TIA-1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance. Molecular Oncology. 9: 167-78. PMID 25224594 DOI: 10.1016/j.molonc.2014.07.017  1
2014 Oltean S, Qiu Y, Ferguson JK, Stevens M, Neal C, Russell A, Kaura A, Arkill KP, Harris K, Symonds C, Lacey K, Wijeyaratne L, Gammons M, Wylie E, Hulse RP, ... ... Bates DO, et al. Vascular Endothelial Growth Factor-A165b Is Protective and Restores Endothelial Glycocalyx in Diabetic Nephropathy. Journal of the American Society of Nephrology : Jasn. PMID 25542969 DOI: 10.1681/ASN.2014040350  1
2014 Mavrou A, Brakspear K, Hamdollah-Zadeh M, Damodaran G, Babaei-Jadidi R, Oxley J, Gillatt DA, Ladomery MR, Harper SJ, Bates DO, Oltean S. Serine-arginine protein kinase 1 (SRPK1) inhibition as a potential novel targeted therapeutic strategy in prostate cancer. Oncogene. PMID 25381816 DOI: 10.1038/onc.2014.360  0.52
2014 Kikuchi R, Nakamura K, MacLauchlan S, Ngo DT, Shimizu I, Fuster JJ, Katanasaka Y, Yoshida S, Qiu Y, Yamaguchi TP, Matsushita T, Murohara T, Gokce N, Bates DO, Hamburg NM, et al. An antiangiogenic isoform of VEGF-A contributes to impaired vascularization in peripheral artery disease. Nature Medicine. 20: 1464-71. PMID 25362254 DOI: 10.1038/nm.3703  0.48
2014 Hulse RP, Beazley-Long N, Hua J, Kennedy H, Prager J, Bevan H, Qiu Y, Fernandes ES, Gammons MV, Ballmer-Hofer K, Gittenberger de Groot AC, Churchill AJ, Harper SJ, Brain SD, Bates DO, et al. Regulation of alternative VEGF-A mRNA splicing is a therapeutic target for analgesia. Neurobiology of Disease. 71: 245-59. PMID 25151644 DOI: 10.1016/j.nbd.2014.08.012  1
2014 Bills VL, Hamdollah-Zadeh M, Soothill PW, Harper SJ, Bates DO. The role of VEGF-A165b in trophoblast survival. Bmc Pregnancy and Childbirth. 14: 278. PMID 25128406 DOI: 10.1186/1471-2393-14-278  1
2014 Gammons MV, Lucas R, Dean R, Coupland SE, Oltean S, Bates DO. Targeting SRPK1 to control VEGF-mediated tumour angiogenesis in metastatic melanoma. British Journal of Cancer. 111: 477-85. PMID 25010863 DOI: 10.1038/bjc.2014.342  1
2014 Thichanpiang P, Harper SJ, Wongprasert K, Bates DO. TNF-α-induced ICAM-1 expression and monocyte adhesion in human RPE cells is mediated in part through autocrine VEGF stimulation. Molecular Vision. 20: 781-9. PMID 24940033  1
2014 Arkill KP, Qvortrup K, Starborg T, Mantell JM, Knupp C, Michel CC, Harper SJ, Salmon AH, Squire JM, Bates DO, Neal CR. Resolution of the three dimensional structure of components of the glomerular filtration barrier. Bmc Nephrology. 15: 24. PMID 24484633 DOI: 10.1186/1471-2369-15-24  1
2013 Bates DO, Mavrou A, Qiu Y, Carter JG, Hamdollah-Zadeh M, Barratt S, Gammons MV, Millar AB, Salmon AH, Oltean S, Harper SJ. Detection of VEGF-A(xxx)b isoforms in human tissues. Plos One. 8: e68399. PMID 23935865 DOI: 10.1371/journal.pone.0068399  1
2013 Gammons MV, Fedorov O, Ivison D, Du C, Clark T, Hopkins C, Hagiwara M, Dick AD, Cox R, Harper SJ, Hancox JC, Knapp S, Bates DO. Topical antiangiogenic SRPK1 inhibitors reduce choroidal neovascularization in rodent models of exudative AMD. Investigative Ophthalmology & Visual Science. 54: 6052-62. PMID 23887803 DOI: 10.1167/iovs.13-12422  1
2013 Beazley-Long N, Hua J, Jehle T, Hulse RP, Dersch R, Lehrling C, Bevan H, Qiu Y, Lagrèze WA, Wynick D, Churchill AJ, Kehoe P, Harper SJ, Bates DO, Donaldson LF. VEGF-A165b is an endogenous neuroprotective splice isoform of vascular endothelial growth factor A in vivo and in vitro. The American Journal of Pathology. 183: 918-29. PMID 23838428 DOI: 10.1016/j.ajpath.2013.05.031  1
2013 Gammons MV, Dick AD, Harper SJ, Bates DO. SRPK1 inhibition modulates VEGF splicing to reduce pathological neovascularization in a rat model of retinopathy of prematurity. Investigative Ophthalmology & Visual Science. 54: 5797-806. PMID 23761094 DOI: 10.1167/iovs.13-11634  1
2012 Bates DO, Catalano PJ, Symonds KE, Varey AH, Ramani P, O'Dwyer PJ, Giantonio BJ, Meropol NJ, Benson AB, Harper SJ. Predictive value of the antiangiogenic VEGF splice variant expression for bevacizumab efficacy in the phase III trial of bevacizumab and FOLFOX4 versus FOLFOX4 in previously treated patients with advanced colorectal cancer (ECOG E3200T2). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 545. PMID 27983263 DOI: 10.1200/jco.2012.30.4_suppl.545  1
2012 Bates DO, Catalano PJ, Symonds KE, Varey AH, Ramani P, O'Dwyer PJ, Giantonio BJ, Meropol NJ, Benson AB, Harper SJ. Association between VEGF splice isoforms and progression-free survival in metastatic colorectal cancer patients treated with bevacizumab. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 6384-91. PMID 23104894 DOI: 10.1158/1078-0432.CCR-12-2223  1
2012 Oltean S, Gammons M, Hulse R, Hamdollah-Zadeh M, Mavrou A, Donaldson L, Salmon AH, Harper SJ, Ladomery MR, Bates DO. SRPK1 inhibition in vivo: modulation of VEGF splicing and potential treatment for multiple diseases. Biochemical Society Transactions. 40: 831-5. PMID 22817743 DOI: 10.1042/BST20120051  1
2012 Oltean S, Neal CR, Mavrou A, Patel P, Ahad T, Alsop C, Lee T, Sison K, Qiu Y, Harper SJ, Bates DO, Salmon AH. VEGF165b overexpression restores normal glomerular water permeability in VEGF164-overexpressing adult mice. American Journal of Physiology. Renal Physiology. 303: F1026-36. PMID 22811490 DOI: 10.1152/ajprenal.00410.2011  1
2012 Salmon AH, Ferguson JK, Burford JL, Gevorgyan H, Nakano D, Harper SJ, Bates DO, Peti-Peterdi J. Loss of the endothelial glycocalyx links albuminuria and vascular dysfunction. Journal of the American Society of Nephrology : Jasn. 23: 1339-50. PMID 22797190 DOI: 10.1681/ASN.2012010017  1
2012 Qiu Y, Seager M, Osman A, Castle-Miller J, Bevan H, Tortonese DJ, Murphy D, Harper SJ, Fraser HM, Donaldson LF, Bates DO. Ovarian VEGF(165)b expression regulates follicular development, corpus luteum function and fertility. Reproduction (Cambridge, England). 143: 501-11. PMID 22232745 DOI: 10.1530/REP-11-0091  1
2011 Woolard J, Vousden W, Moss SJ, Krishnakumar A, Gammons MV, Nowak DG, Dixon N, Micklefield J, Spannhoff A, Bedford MT, Gregory MA, Martin CJ, Leadlay PF, Zhang MQ, Harper SJ, ... Bates DO, et al. Borrelidin modulates the alternative splicing of VEGF in favour of anti-angiogenic isoforms. Chemical Science (Royal Society of Chemistry : 2010). 2011: 273-278. PMID 22822423 DOI: 10.1039/C0SC00297F  1
2011 Amin EM, Oltean S, Hua J, Gammons MV, Hamdollah-Zadeh M, Welsh GI, Cheung MK, Ni L, Kase S, Rennel ES, Symonds KE, Nowak DG, Royer-Pokora B, Saleem MA, Hagiwara M, ... ... Bates DO, et al. WT1 mutants reveal SRPK1 to be a downstream angiogenesis target by altering VEGF splicing. Cancer Cell. 20: 768-80. PMID 22172722 DOI: 10.1016/j.ccr.2011.10.016  1
2011 Rennel ES, Regula JT, Harper SJ, Thomas M, Klein C, Bates DO. A human neutralizing antibody specific to Ang-2 inhibits ocular angiogenesis. Microcirculation (New York, N.Y. : 1994). 18: 598-607. PMID 21851472 DOI: 10.1111/j.1549-8719.2011.00120.x  1
2011 Bills VL, Salmon AH, Harper SJ, Overton TG, Neal CR, Jeffery B, Soothill PW, Bates DO. Impaired vascular permeability regulation caused by the VEGF165b splice variant in pre-eclampsia Bjog: An International Journal of Obstetrics and Gynaecology. 118: 1253-1261. PMID 21668772 DOI: 10.1111/j.1471-0528.2011.02925.x  1
2011 Carter JG, Cherry J, Williams K, Turner S, Bates DO, Churchill AJ. Splicing factor polymorphisms, the control of VEGF isoforms and association with angiogenic eye disease. Current Eye Research. 36: 328-35. PMID 21309690 DOI: 10.3109/02713683.2010.548892  0.84
2011 Emmett MS, Lanati S, Dunn DB, Stone OA, Bates DO. CCR7 mediates directed growth of melanomas towards lymphatics. Microcirculation (New York, N.Y. : 1994). 18: 172-82. PMID 21166932 DOI: 10.1111/j.1549-8719.2010.00074.x  0.76
2010 Harper SJ, Bates DO. Glomerular filtration barrier and molecular segregation: guilty as charged? Journal of the American Society of Nephrology : Jasn. 21: 2009-11. PMID 21071522 DOI: 10.1681/ASN.2010101071  1
2010 Lanati S, Dunn DB, Roussigné M, Emmett MS, Carriere V, Jullien D, Budge J, Fryer J, Erard M, Cailler F, Girard JP, Bates DO. Chemotrap-1: an engineered soluble receptor that blocks chemokine-induced migration of metastatic cancer cells in vivo. Cancer Research. 70: 8138-48. PMID 20736366 DOI: 10.1158/0008-5472.CAN-10-0175  1
2010 Wu WK, Llewellyn OP, Bates DO, Nicholson LB, Dick AD. IL-10 regulation of macrophage VEGF production is dependent on macrophage polarisation and hypoxia. Immunobiology. 215: 796-803. PMID 20692534 DOI: 10.1016/j.imbio.2010.05.025  0.76
2010 Foster RR, Welsh GI, Satchell SC, Marlow RD, Wherlock MD, Pons D, Mathieson PW, Bates DO, Saleem MA. Functional distinctions in cytosolic calcium regulation between cells of the glomerular filtration barrier. Cell Calcium. 48: 44-53. PMID 20674014 DOI: 10.1016/j.ceca.2010.06.005  1
2010 Peiris-Pagès M, Harper SJ, Bates DO, Ramani P. Balance of pro- versus anti-angiogenic splice isoforms of vascular endothelial growth factor as a regulator of neuroblastoma growth. The Journal of Pathology. 222: 138-47. PMID 20662003 DOI: 10.1002/path.2746  1
2010 Emmett MS, Symonds KE, Rigby H, Cook MG, Price R, Metcalfe C, Orlando A, Bates DO. Prediction of melanoma metastasis by the Shields index based on lymphatic vessel density. Bmc Cancer. 10: 208. PMID 20478045 DOI: 10.1186/1471-2407-10-208  0.76
2010 Cristofaro B, Stone OA, Caporali A, Dawbarn D, Ieronimakis N, Reyes M, Madeddu P, Bates DO, Emanueli C. Neurotrophin-3 is a novel angiogenic factor capable of therapeutic neovascularization in a mouse model of limb ischemia. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 1143-50. PMID 20360537 DOI: 10.1161/ATVBAHA.109.205468  1
2010 Hua J, Spee C, Kase S, Rennel ES, Magnussen AL, Qiu Y, Varey A, Dhayade S, Churchill AJ, Harper SJ, Bates DO, Hinton DR. Recombinant human VEGF165b inhibits experimental choroidal neovascularization. Investigative Ophthalmology & Visual Science. 51: 4282-8. PMID 20237252 DOI: 10.1167/iovs.09-4360  1
2010 Magnussen AL, Rennel ES, Hua J, Bevan HS, Beazley Long N, Lehrling C, Gammons M, Floege J, Harper SJ, Agostini HT, Bates DO, Churchill AJ. VEGF-A165b is cytoprotective and antiangiogenic in the retina. Investigative Ophthalmology & Visual Science. 51: 4273-81. PMID 20237249 DOI: 10.1167/iovs.09-4296  1
2010 Varet J, Douglas SK, Gilmartin L, Medford AR, Bates DO, Harper SJ, Millar AB. VEGF in the lung: a role for novel isoforms. American Journal of Physiology. Lung Cellular and Molecular Physiology. 298: L768-74. PMID 20228180 DOI: 10.1152/ajplung.00353.2009  1
2010 Nowak DG, Amin EM, Rennel ES, Hoareau-Aveilla C, Gammons M, Damodoran G, Hagiwara M, Harper SJ, Woolard J, Ladomery MR, Bates DO. Regulation of vascular endothelial growth factor (VEGF) splicing from pro-angiogenic to anti-angiogenic isoforms: a novel therapeutic strategy for angiogenesis. The Journal of Biological Chemistry. 285: 5532-40. PMID 19906640 DOI: 10.1074/jbc.M109.074930  1
2009 Qiu Y, Hoareau-Aveilla C, Oltean S, Harper SJ, Bates DO. The anti-angiogenic isoforms of VEGF in health and disease. Biochemical Society Transactions. 37: 1207-13. PMID 19909248 DOI: 10.1042/BST0371207  1
2009 Rennel ES, Varey AH, Churchill AJ, Wheatley ER, Stewart L, Mather S, Bates DO, Harper SJ. VEGF(121)b, a new member of the VEGF(xxx)b family of VEGF-A splice isoforms, inhibits neovascularisation and tumour growth in vivo. British Journal of Cancer. 101: 1183-93. PMID 19707198 DOI: 10.1038/sj.bjc.6605249  1
2009 Woolard J, Bevan HS, Harper SJ, Bates DO. Molecular diversity of VEGF-A as a regulator of its biological activity. Microcirculation (New York, N.Y. : 1994). 16: 572-92. PMID 19521900 DOI: 10.1080/10739680902997333  1
2009 Rennel ES, Harper SJ, Bates DO. Therapeutic potential of manipulating VEGF splice isoforms in oncology. Future Oncology (London, England). 5: 703-12. PMID 19519209 DOI: 10.2217/fon.09.33  1
2009 Benest AV, Bates DO. Measurement of angiogenic phenotype by use of two-dimensional mesenteric angiogenesis assay. Methods in Molecular Biology (Clifton, N.J.). 467: 251-70. PMID 19301676  1
2009 Salmon AHJ, Neal CR, Sage LM, Glass CA, Harper SJ, Bates DO. Angiopoietin-1 alters microvascular permeability coefficients in vivo via modification of endothelial glycocalyx Cardiovascular Research. 83: 24-33. PMID 19297368 DOI: 10.1093/cvr/cvp093  1
2009 Foster RR, Zadeh MA, Welsh GI, Satchell SC, Ye Y, Mathieson PW, Bates DO, Saleem MA. Flufenamic acid is a tool for investigating TRPC6-mediated calcium signalling in human conditionally immortalised podocytes and HEK293 cells. Cell Calcium. 45: 384-90. PMID 19232718 DOI: 10.1016/j.ceca.2009.01.003  1
2009 Stone OA, Richer C, Emanueli C, van Weel V, Quax PH, Katare R, Kraenkel N, Campagnolo P, Barcelos LS, Siragusa M, Sala-Newby GB, Baldessari D, Mione M, Vincent MP, Benest AV, ... ... Bates DO, et al. Critical role of tissue kallikrein in vessel formation and maturation: implications for therapeutic revascularization. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 657-64. PMID 19164804 DOI: 10.1161/ATVBAHA.108.182139  1
2009 Bills VL, Varet J, Millar A, Harper SJ, Soothill PW, Bates DO. Failure to up-regulate VEGF165b in maternal plasma is a first trimester predictive marker for pre-eclampsia. Clinical Science (London, England : 1979). 116: 265-72. PMID 18826376 DOI: 10.1042/CS20080270  1
2008 Bevan HS, Van Den Akker NMS, Qiu Y, Polman JAE, Foster RR, Yem J, Nishikawa A, Satchell SC, Harper SJ, Gittenberger-De Groot AC, Bates DO. The alternatively spliced anti-angiogenic family of VEGF isoforms VEGF xxxb in human kidney development Nephron - Physiology. 110. PMID 19039247 DOI: 10.1159/000177614  1
2008 Harper SJ, Bates DO. VEGF-A splicing: the key to anti-angiogenic therapeutics? Nature Reviews. Cancer. 8: 880-7. PMID 18923433 DOI: 10.1038/nrc2505  1
2008 Nowak DG, Woolard J, Amin EM, Konopatskaya O, Saleem MA, Churchill AJ, Ladomery MR, Harper SJ, Bates DO. Expression of pro- and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors. Journal of Cell Science. 121: 3487-95. PMID 18843117 DOI: 10.1242/jcs.016410  1
2008 Hamdollah Zadeh MA, Glass CA, Magnussen A, Hancox JC, Bates DO. VEGF-mediated elevated intracellular calcium and angiogenesis in human microvascular endothelial cells in vitro are inhibited by dominant negative TRPC6. Microcirculation (New York, N.Y. : 1994). 15: 605-14. PMID 18800249 DOI: 10.1080/10739680802220323  1
2008 Foster RR, Slater SC, Seckley J, Kerjaschki D, Bates DO, Mathieson PW, Satchell SC. Vascular endothelial growth factor-C, a potential paracrine regulator of glomerular permeability, increases glomerular endothelial cell monolayer integrity and intracellular calcium American Journal of Pathology. 173: 938-948. PMID 18772335 DOI: 10.2353/ajpath.2008.070416  1
2008 Rennel ES, Hamdollah-Zadeh MA, Wheatley ER, Magnussen A, Schüler Y, Kelly SP, Finucane C, Ellison D, Cebe-Suarez S, Ballmer-Hofer K, Mather S, Stewart L, Bates DO, Harper SJ. Recombinant human VEGF165b protein is an effective anti-cancer agent in mice. European Journal of Cancer (Oxford, England : 1990). 44: 1883-94. PMID 18657413 DOI: 10.1016/j.ejca.2008.05.027  1
2008 Kawamura H, Li X, Harper SJ, Bates DO, Claesson-Welsh L. Vascular endothelial growth factor (VEGF)-A165b is a weak in vitro agonist for VEGF receptor-2 due to lack of coreceptor binding and deficient regulation of kinase activity. Cancer Research. 68: 4683-92. PMID 18559514 DOI: 10.1158/0008-5472.CAN-07-6577  1
2008 Benest AV, Stone OA, Miller WH, Glover CP, Uney JB, Baker AH, Harper SJ, Bates DO. Arteriolar genesis and angiogenesis induced by endothelial nitric oxide synthase overexpression results in a mature vasculature. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 1462-8. PMID 18497305 DOI: 10.1161/ATVBAHA.108.169375  1
2008 Varey AHR, Rennel ES, Qiu Y, Bevan HS, Perrin RM, Raffy S, Dixon AR, Paraskeva C, Zaccheo O, Hassan AB, Harper SJ, Bates DO. VEGF165b, an antiangiogenic VEGF-A isoform, binds and inhibits bevacizumab treatment in experimental colorectal carcinoma: Balance of pro- and antiangiogenic VEGF-A isoforms has implications for therapy British Journal of Cancer. 98: 1366-1379. PMID 18349829 DOI: 10.1038/sj.bjc.6604308  1
2008 Benest AV, Harper SJ, Herttuala SY, Alitalo K, Bates DO. VEGF-C induced angiogenesis preferentially occurs at a distance from lymphangiogenesis Cardiovascular Research. 78: 315-323. PMID 18065770 DOI: 10.1093/cvr/cvm094  1
2008 Qiu Y, Bevan H, Weeraperuma S, Wratting D, Murphy D, Neal CR, Bates DO, Harper SJ. Mammary alveolar development during lactation is inhibited by the endogenous antiangiogenic growth factor isoform, VEGF165b Faseb Journal. 22: 1104-1112. PMID 18032632 DOI: 10.1096/fj.07-9718com  1
2007 Perrin RM, Harper SJ, Bates DO. A role for the endothelial glycocalyx in regulating microvascular permeability in diabetes mellitus Cell Biochemistry and Biophysics. 49: 65-72. PMID 17906361 DOI: 10.1007/s12013-007-0041-6  1
2007 Perrin RM, Harper SJ, Corrall R, Bates DO. Hyperglycemia stimulates a sustained increase in hydraulic conductivity in vivo without any change in reflection coefficient Microcirculation. 14: 683-696. PMID 17885994 DOI: 10.1080/10739680701436129  1
2007 Salmon AH, Toma I, Sipos A, Muston PR, Harper SJ, Bates DO, Neal CR, Peti-Peterdi J. Evidence for restriction of fluid and solute movement across the glomerular capillary wall by the subpodocyte space. American Journal of Physiology. Renal Physiology. 293: F1777-86. PMID 17804486 DOI: 10.1152/ajprenal.00187.2007  1
2007 Neal CR, Muston PR, Njegovan D, Verrill R, Harper SJ, Deen WM, Bates DO. Glomerular filtration into the subpodocyte space is highly restricted under physiological perfusion conditions. American Journal of Physiology. Renal Physiology. 293: F1787-98. PMID 17715264 DOI: 10.1152/ajprenal.00157.2007  1
2007 Pritchard-Jones RO, Dunn DB, Qiu Y, Varey AH, Orlando A, Rigby H, Harper SJ, Bates DO. Expression of VEGF(xxx)b, the inhibitory isoforms of VEGF, in malignant melanoma. British Journal of Cancer. 97: 223-30. PMID 17595666 DOI: 10.1038/sj.bjc.6603839  1
2007 Cross SE, Richards SK, Clark A, Benest AV, Bates DO, Mathieson PW, Johnson PR, Harper SJ, Smith RM. Vascular endothelial growth factor as a survival factor for human islets: effect of immunosuppressive drugs. Diabetologia. 50: 1423-32. PMID 17476476 DOI: 10.1007/s00125-007-0670-8  1
2007 Shields JD, Emmett MS, Dunn DB, Joory KD, Sage LM, Rigby H, Mortimer PS, Orlando A, Levick JR, Bates DO. Chemokine-mediated migration of melanoma cells towards lymphatics--a mechanism contributing to metastasis. Oncogene. 26: 2997-3005. PMID 17130836 DOI: 10.1038/sj.onc.1210114  1
2007 Ladomery MR, Harper SJ, Bates DO. Alternative splicing in angiogenesis: the vascular endothelial growth factor paradigm. Cancer Letters. 249: 133-42. PMID 17027147 DOI: 10.1016/j.canlet.2006.08.015  1
2006 Benest AV, Salmon AH, Wang W, Glover CP, Uney J, Harper SJ, Bates DO. VEGF and angiopoietin-1 stimulate different angiogenic phenotypes that combine to enhance functional neovascularization in adult tissue Microcirculation. 13: 423-437. PMID 16864410 DOI: 10.1080/10739680600775940  1
2006 Joory KD, Levick JR, Mortimer PS, Bates DO. Vascular endothelial growth factor-C (VEGF-C) expression in normal human tissues. Lymphatic Research and Biology. 4: 73-82. PMID 16808669 DOI: 10.1089/lrb.2006.4.73  1
2006 Cheng HW, James AF, Foster RR, Hancox JC, Bates DO. VEGF activates receptor-operated cation channels in human microvascular endothelial cells Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 1768-1776. PMID 16763162 DOI: 10.1161/01.ATV.0000231518.86795.0f  1
2006 Konopatskaya O, Churchill AJ, Harper SJ, Bates DO, Gardiner TA. VEGF165b, an endogenous C-terminal splice variant of VEGF, inhibits retinal neovascularization in mice. Molecular Vision. 12: 626-32. PMID 16735996  1
2006 Hill AJ, Hinton JM, Cheng H, Gao Z, Bates DO, Hancox JC, Langton PD, James AF. A TRPC-like non-selective cation current activated by alpha 1-adrenoceptors in rat mesenteric artery smooth muscle cells. Cell Calcium. 40: 29-40. PMID 16697039 DOI: 10.1016/j.ceca.2006.03.007  0.32
2006 Foster RR, Satchell SC, Seckley J, Emmett MS, Joory K, Xing CY, Saleem MA, Mathieson PW, Bates DO, Harper SJ. VEGF-C promotes survival in podocytes American Journal of Physiology - Renal Physiology. 291. PMID 16525158 DOI: 10.1152/ajprenal.00431.2005  1
2006 Fiedler U, Christian S, Koidl S, Kerjaschki D, Emmett MS, Bates DO, Christofori G, Augustin HG. The sialomucin CD34 is a marker of lymphatic endothelial cells in human tumors American Journal of Pathology. 168: 1045-1053. PMID 16507917 DOI: 10.2353/ajpath.2006.050554  1
2006 Bates DO, MacMillan PP, Manjaly JG, Qiu Y, Hudson SJ, Bevan HS, Hunter AJ, Soothill PW, Read M, Donaldson LF, Harper SJ. The endogenous anti-angiogenic family of splice variants of VEGF, VEGFxxxb, are down-regulated in pre-eclamptic placentae at term. Clinical Science (London, England : 1979). 110: 575-85. PMID 16451124 DOI: 10.1042/CS20050292  1
2006 Glass CA, Harper SJ, Bates DO. The anti-angiogenic VEGF isoform VEGF165b transiently increases hydraulic conductivity, probably through VEGF receptor 1 in vivo. The Journal of Physiology. 572: 243-57. PMID 16423853 DOI: 10.1113/jphysiol.2005.103127  1
2006 Glass CA, Perrin RM, Pocock TM, Bates DO. Transient osmotic absorption of fluid in microvessels exposed to low concentrations of dimethyl sulfoxide Microcirculation. 13: 29-40. PMID 16393944 DOI: 10.1080/10739680500383464  1
2006 Salmon AHJ, Neal CR, Bates DO, Harper SJ. Vascular endothelial growth factor increases the ultrafiltration coefficient in isolated intact Wistar rat glomeruli Journal of Physiology. 570: 141-156. PMID 16239266 DOI: 10.1113/jphysiol.2005.099184  1
2005 Bates DO, Harper SJ. Therapeutic potential of inhibitory VEGF splice variants. Future Oncology (London, England). 1: 467-73. PMID 16556023 DOI: 10.2217/14796694.1.4.467  1
2005 Perrin RM, Konopatskaya O, Qiu Y, Harper S, Bates DO, Churchill AJ. Diabetic retinopathy is associated with a switch in splicing from anti- to pro-angiogenic isoforms of vascular endothelial growth factor Diabetologia. 48: 2422-2427. PMID 16193288 DOI: 10.1007/s00125-005-1951-8  1
2005 Neal CR, Crook H, Bell E, Harper SJ, Bates DO. Three-dimensional reconstruction of glomeruli by electron microscopy reveals a distinct restrictive urinary subpodocyte space Journal of the American Society of Nephrology. 16: 1223-1235. PMID 15829713 DOI: 10.1681/ASN.2004100822  1
2005 Glass CA, Pocock TM, Curry FE, Bates DO. Cytosolic Ca2+ concentration and rate of increase of the cytosolic Ca2+ concentration in the regulation of vascular permeability in Rana in vivo. The Journal of Physiology. 564: 817-27. PMID 15718259 DOI: 10.1113/jphysiol.2005.083220  1
2005 Coward RJ, Foster RR, Patton D, Ni L, Lennon R, Bates DO, Harper SJ, Mathieson PW, Saleem MA. Nephrotic plasma alters slit diaphragm-dependent signaling and translocates nephrin, Podocin, and CD2 associated protein in cultured human podocytes. Journal of the American Society of Nephrology : Jasn. 16: 629-37. PMID 15659563 DOI: 10.1681/ASN.2004030172  1
2005 Foster RR, Saleem MA, Mathieson PW, Bates DO, Harper SJ. Vascular endothelial growth factor and nephrin interact and reduce apoptosis in human podocytes American Journal of Physiology - Renal Physiology. 288. PMID 15339792 DOI: 10.1152/ajprenal.00146.2004  1
2004 Woolard J, Wang WY, Bevan HS, Qiu Y, Morbidelli L, Pritchard-Jones RO, Cui TG, Sugiono M, Waine E, Perrin R, Foster R, Digby-Bell J, Shields JD, Whittles CE, Mushens RE, ... ... Bates DO, et al. VEGF165b, an inhibitory vascular endothelial growth factor splice variant: mechanism of action, in vivo effect on angiogenesis and endogenous protein expression. Cancer Research. 64: 7822-35. PMID 15520188 DOI: 10.1158/0008-5472.CAN-04-0934  1
2004 Wang WY, Whittles CE, Harper SJ, Bates DO. An adenovirus-mediated gene-transfer model of angiogenesis in rat mesentery. Microcirculation (New York, N.Y. : 1994). 11: 361-75. PMID 15280075 DOI: 10.1080/10739680490437568  1
2004 Neal CR, Hunter AJ, Harper SJ, Soothill PW, Bates DO. Plasma from women with severe pre-eclampsia increases microvascular permeability in an animal model in vivo Clinical Science. 107: 399-405. PMID 15186215 DOI: 10.1042/CS20040018  1
2004 Glass CA, Bates DO. The role of endothelial cell Ca2+ store release in the regulation of microvascular permeability in vivo. Experimental Physiology. 89: 343-51. PMID 15123553 DOI: 10.1113/expphysiol.2003.026948  0.92
2004 Shields JD, Borsetti M, Rigby H, Harper SJ, Mortimer PS, Levick JR, Orlando A, Bates DO. Lymphatic density and metastatic spread in human malignant melanoma. British Journal of Cancer. 90: 693-700. PMID 14760386 DOI: 10.1038/sj.bjc.6601571  1
2004 Cui TG, Foster RR, Saleem M, Mathieson PW, Gillatt DA, Bates DO, Harper SJ. Differentiated human podocytes endogenously express an inhibitory isoform of vascular endothelial growth factor (VEGF165b) mRNA and protein American Journal of Physiology - Renal Physiology. 286. PMID 14644752  1
2004 Pocock TM, Foster RR, Bates DO. Evidence of a role for TRPC channels in VEGF-mediated increased vascular permeability in vivo American Journal of Physiology - Heart and Circulatory Physiology. 286. PMID 14551041  1
2003 Harper SJ, Bates DO. Endothelial permeability in uremia. Kidney International. Supplement. S41-4. PMID 12694306 DOI: 10.1046/j.1523-1755.63.s84.15.x  1
2003 Foster RR, Hole R, Anderson K, Satchell SC, Coward RJ, Mathieson PW, Gillatt DA, Saleem MA, Bates DO, Harper SJ. Functional evidence that vascular endothelial growth factor may act as an autocrine factor on human podocytes American Journal of Physiology - Renal Physiology. 284. PMID 12620928  1
2003 Glass CA, Bates DO. Role of endothelial Ca2+ stores in the regulation of hydraulic conductivity of Rana microvessels in vivo. American Journal of Physiology. Heart and Circulatory Physiology. 284: H1468-78. PMID 12511429 DOI: 10.1152/ajpheart.00585.2002  0.92
2002 Bates DO, Cui TG, Doughty JM, Winkler M, Sugiono M, Shields JD, Peat D, Gillatt D, Harper SJ. VEGF165b, an inhibitory splice variant of vascular endothelial growth factor, is down-regulated in renal cell carcinoma. Cancer Research. 62: 4123-31. PMID 12124351  1
2002 Harper SJ, Tomson CR, Bates DO. Human uremic plasma increases microvascular permeability to water and proteins in vivo. Kidney International. 61: 1416-22. PMID 11918748 DOI: 10.1046/j.1523-1755.2002.00252.x  1
2001 Bates DO, Heald RI, Curry FE, Williams B. Vascular endothelial growth factor increases Rana vascular permeability and compliance by different signalling pathways. The Journal of Physiology. 533: 263-72. PMID 11351033  1
2000 Pocock TM, Williams B, Curry FE, Bates DO. VEGF and ATP act by different mechanisms to increase microvascular permeability and endothelial [Ca(2+)](i). American Journal of Physiology. Heart and Circulatory Physiology. 279: H1625-34. PMID 11009449  1
1997 Bates DO, Curry FE. Vascular endothelial growth factor increases microvascular permeability via a Ca(2+)-dependent pathway. The American Journal of Physiology. 273: H687-94. PMID 9277485  1
1996 Bates DO, Curry FE. Vascular endothelial growth factor increases hydraulic conductivity of isolated perfused microvessels. The American Journal of Physiology. 271: H2520-8. PMID 8997313  1
1994 Bates DO, Levick JR, Mortimer PS. Starling pressures in the human arm and their alteration in postmastectomy oedema. The Journal of Physiology. 477: 355-63. PMID 7932226  1
1994 Bates DO, Levick JR, Mortimer PS. Quantification of rate and depth of pitting in human edema using an electronic tonometer. Lymphology. 27: 159-72. PMID 7898130  1
1993 Luetolf O, Bull RH, Bates DO, Mortimer PS. Capillary underperfusion in chronic venous insufficiency: a cause for leg ulceration? The British Journal of Dermatology. 128: 249-54. PMID 8471507  1
1993 Bates DO, Levick JR, Mortimer PS. Change in macromolecular composition of interstitial fluid from swollen arms after breast cancer treatment, and its implications. Clinical Science (London, England : 1979). 85: 737-46. PMID 8287667  1
1992 Bull RH, Bates DO, Mortimer PS. Intravital video-capillaroscopy for the study of the microcirculation in psoriasis. The British Journal of Dermatology. 126: 436-45. PMID 1610683  1
1992 Bates DO, Levick JR, Mortimer PS. Subcutaneous interstitial fluid pressure and arm volume in lymphoedema. International Journal of Microcirculation, Clinical and Experimental / Sponsored by the European Society For Microcirculation. 11: 359-73. PMID 1459796  1
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