Tim Osborne - Publications

Affiliations: 
University of Birmingham, Birmingham, England, United Kingdom 

31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Costford SR, Brouwers B, Hopf ME, Sparks LM, Dispagna M, Gomes AP, Cornnell HH, Petucci C, Phelan P, Xie H, Yi F, Walter GA, Osborne TF, Sinclair DA, Mynatt RL, et al. Skeletal muscle overexpression of nicotinamide phosphoribosyl transferase in mice coupled with voluntary exercise augments exercise endurance. Molecular Metabolism. PMID 29146412 DOI: 10.1016/J.Molmet.2017.10.012  0.01
2017 Key CC, Liu M, Kurtz CL, Chung S, Boudyguina E, Dinh TA, Bashore A, Phelan PE, Freedman BI, Osborne TF, Zhu X, Ma L, Sethupathy P, Biddinger SB, Parks JS. Hepatocyte ABCA1 Deletion Impairs Liver Insulin Signaling and Lipogenesis. Cell Reports. 19: 2116-2129. PMID 28591582 DOI: 10.1016/J.Celrep.2017.05.032  0.01
2017 Karimian Azari E, Smith KR, Yi F, Osborne TF, Bizzotto R, Mari A, Pratley RE, Kyriazis GA. Inhibition of sweet chemosensory receptors alters insulin responses during glucose ingestion in healthy adults: a randomized crossover interventional study. The American Journal of Clinical Nutrition. PMID 28251932 DOI: 10.3945/Ajcn.116.146001  0.01
2016 Kim KY, Jang HJ, Yang YR, Park KI, Seo J, Shin IW, Jeon TI, Ahn SC, Suh PG, Osborne TF, Seo YK. Corrigendum: SREBP-2/PNPLA8 axis improves non-alcoholic fatty liver disease through activation of autophagy. Scientific Reports. 6: 37794. PMID 27897271 DOI: 10.1038/Srep37794  0.01
2016 Kim KY, Jang HJ, Yang YR, Park KI, Seo J, Shin IW, Jeon TI, Ahn SC, Suh PG, Osborne TF, Seo YK. SREBP-2/PNPLA8 axis improves non-alcoholic fatty liver disease through activation of autophagy. Scientific Reports. 6: 35732. PMID 27767079 DOI: 10.1038/Srep35732  0.01
2016 Roqueta-Rivera M, Esquejo RM, Phelan PE, Sandor K, Daniel B, Foufelle F, Ding J, Li X, Khorasanizadeh S, Osborne TF. SETDB2 Links Glucocorticoid to Lipid Metabolism through Insig2a Regulation. Cell Metabolism. PMID 27568546 DOI: 10.1016/J.Cmet.2016.07.025  0.01
2016 Jeon TI, Osborne TF. miRNA and cholesterol homeostasis. Biochimica Et Biophysica Acta. PMID 26778752 DOI: 10.1016/J.Bbalip.2016.01.005  0.01
2015 Vergnes L, Chin RG, de Aguiar Vallim T, Fong LG, Osborne TF, Young SG, Reue K. SREBP-2-deficient and hypomorphic mice reveal roles for SREBP-2 in embryonic development and SREBP-1c expression. Journal of Lipid Research. PMID 26685326 DOI: 10.1194/Jlr.M064022  0.01
2015 Matsumura Y, Nakaki R, Inagaki T, Yoshida A, Kano Y, Kimura H, Tanaka T, Tsutsumi S, Nakao M, Doi T, Fukami K, Osborne TF, Kodama T, Aburatani H, Sakai J. H3K4/H3K9me3 Bivalent Chromatin Domains Targeted by Lineage-Specific DNA Methylation Pauses Adipocyte Differentiation. Molecular Cell. 60: 584-96. PMID 26590716 DOI: 10.1016/J.Molcel.2015.10.025  0.01
2015 Abe Y, Rozqie R, Matsumura Y, Kawamura T, Nakaki R, Tsurutani Y, Tanimura-Inagaki K, Shiono A, Magoori K, Nakamura K, Ogi S, Kajimura S, Kimura H, Tanaka T, Fukami K, Osborne TF, et al. JMJD1A is a signal-sensing scaffold that regulates acute chromatin dynamics via SWI/SNF association for thermogenesis. Nature Communications. 6: 7052. PMID 25948511 DOI: 10.1038/Ncomms8052  0.01
2015 Inagaki T, Iwasaki S, Matsumura Y, Kawamura T, Tanaka T, Abe Y, Yamasaki A, Tsurutani Y, Yoshida A, Chikaoka Y, Nakamura K, Magoori K, Nakaki R, Osborne TF, Fukami K, et al. The FBXL10/KDM2B scaffolding protein associates with novel polycomb repressive complex-1 to regulate adipogenesis. The Journal of Biological Chemistry. 290: 4163-77. PMID 25533466 DOI: 10.1074/Jbc.M114.626929  0.01
2014 Masri S, Rigor P, Cervantes M, Ceglia N, Sebastian C, Xiao C, Roqueta-Rivera M, Deng C, Osborne TF, Mostoslavsky R, Baldi P, Sassone-Corsi P. Partitioning circadian transcription by SIRT6 leads to segregated control of cellular metabolism. Cell. 158: 659-72. PMID 25083875 DOI: 10.1016/J.Cell.2014.06.050  0.01
2014 Im SS, Young SG, Raffatellu M, Osborne TF. Response to Gerlic et al. Cell Metabolism. 19: 346-7. PMID 24606892 DOI: 10.1016/J.Cmet.2014.02.016  0.01
2014 Esquejo RM, Jeon TI, Osborne TF. Lipid-cell cycle nexus: SREBP regulates microRNAs targeting Fbxw7. Cell Cycle (Georgetown, Tex.). 13: 339-40. PMID 24335356 DOI: 10.4161/Cc.27509  0.01
2013 Jeon TI, Esquejo RM, Roqueta-Rivera M, Phelan PE, Moon YA, Govindarajan SS, Esau CC, Osborne TF. An SREBP-responsive microRNA operon contributes to a regulatory loop for intracellular lipid homeostasis. Cell Metabolism. 18: 51-61. PMID 23823476 DOI: 10.1016/J.Cmet.2013.06.010  0.01
2013 Kidani Y, Elsaesser H, Hock MB, Vergnes L, Williams KJ, Argus JP, Marbois BN, Komisopoulou E, Wilson EB, Osborne TF, Graeber TG, Reue K, Brooks DG, Bensinger SJ. Sterol regulatory element-binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity. Nature Immunology. 14: 489-99. PMID 23563690 DOI: 10.1038/Ni.2570  0.01
2012 Shin DJ, Joshi P, Hong SH, Mosure K, Shin DG, Osborne TF. Genome-wide analysis of FoxO1 binding in hepatic chromatin: potential involvement of FoxO1 in linking retinoid signaling to hepatic gluconeogenesis. Nucleic Acids Research. 40: 11499-509. PMID 23066095 DOI: 10.1093/Nar/Gks932  0.01
2012 Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... Osborne TF, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496  0.01
2012 Im SS, Osborne TF. Protection from bacterial-toxin-induced apoptosis in macrophages requires the lipogenic transcription factor sterol regulatory element binding protein 1a. Molecular and Cellular Biology. 32: 2196-202. PMID 22493063 DOI: 10.1128/Mcb.06294-11  0.01
2012 Lakie M, Vernooij CA, Osborne TM, Reynolds RF. The resonant component of human physiological hand tremor is altered by slow voluntary movements. The Journal of Physiology. 590: 2471-83. PMID 22431335 DOI: 10.1113/jphysiol.2011.226449  1
2012 Chong HK, Biesinger J, Seo YK, Xie X, Osborne TF. Genome-wide analysis of hepatic LRH-1 reveals a promoter binding preference and suggests a role in regulating genes of lipid metabolism in concert with FXR. Bmc Genomics. 13: 51. PMID 22296850 DOI: 10.1186/1471-2164-13-51  0.01
2012 Freed-Pastor WA, Mizuno H, Zhao X, Langerød A, Moon SH, Rodriguez-Barrueco R, Barsotti A, Chicas A, Li W, Polotskaia A, Bissell MJ, Osborne TF, Tian B, Lowe SW, Silva JM, et al. Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway. Cell. 148: 244-58. PMID 22265415 DOI: 10.1016/J.Cell.2011.12.017  0.01
2012 Jeon TI, Osborne TF. SREBPs: metabolic integrators in physiology and metabolism. Trends in Endocrinology and Metabolism: Tem. 23: 65-72. PMID 22154484 DOI: 10.1016/J.Tem.2011.10.004  0.01
2011 Osborne TF. Sterols for Oxygen: The Metabolic Burden of Microbial SREBP. Molecular Cell. 44: 172-4. PMID 22017866 DOI: 10.1016/J.Molcel.2011.10.004  0.01
2011 Osborne TM, Lakie M. A novel planar tracking technology for physiological image analysis. Journal of Neuroscience Methods. 202: 53-9. PMID 21907238 DOI: 10.1016/j.jneumeth.2011.08.041  1
2011 Jeong YS, Kim D, Lee YS, Kim HJ, Han JY, Im SS, Chong HK, Kwon JK, Cho YH, Kim WK, Osborne TF, Horton JD, Jun HS, Ahn YH, Ahn SM, et al. Integrated expression profiling and genome-wide analysis of ChREBP targets reveals the dual role for ChREBP in glucose-regulated gene expression. Plos One. 6: e22544. PMID 21811631 DOI: 10.1371/Journal.Pone.0022544  0.01
2011 Jeon TI, Seo YK, Osborne TF. Gut bitter taste receptor signalling induces ABCB1 through a mechanism involving CCK. The Biochemical Journal. 438: 33-7. PMID 21592089 DOI: 10.1042/Bj20110009  0.01
2011 Im SS, Yousef L, Blaschitz C, Liu JZ, Edwards RA, Young SG, Raffatellu M, Osborne TF. Linking lipid metabolism to the innate immune response in macrophages through sterol regulatory element binding protein-1a. Cell Metabolism. 13: 540-9. PMID 21531336 DOI: 10.1016/J.Cmet.2011.04.001  0.01
2011 Im SS, Osborne TF. Liver x receptors in atherosclerosis and inflammation. Circulation Research. 108: 996-1001. PMID 21493922 DOI: 10.1161/Circresaha.110.226878  0.01
2011 Seo YK, Jeon TI, Chong HK, Biesinger J, Xie X, Osborne TF. Genome-wide localization of SREBP-2 in hepatic chromatin predicts a role in autophagy. Cell Metabolism. 13: 367-75. PMID 21459322 DOI: 10.1016/J.Cmet.2011.03.005  0.01
2011 Blanc M, Hsieh WY, Robertson KA, Watterson S, Shui G, Lacaze P, Khondoker M, Dickinson P, Sing G, Rodríguez-Martín S, Phelan P, Forster T, Strobl B, Müller M, Riemersma R, ... Osborne T, et al. Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis. Plos Biology. 9: e1000598. PMID 21408089 DOI: 10.1371/Journal.Pbio.1000598  0.01
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