| Year |
Citation |
Score |
| 2023 |
Bhagchandani SH, Yang L, Maiorino L, Ben-Akiva E, Rodrigues KA, Romanov A, Suh H, Aung A, Wu S, Wadhera A, Chakraborty AK, Irvine DJ. Two-dose "extended priming" immunization amplifies humoral immune responses by synchronizing vaccine delivery with the germinal center response. Biorxiv : the Preprint Server For Biology. PMID 38045401 DOI: 10.1101/2023.11.20.563479 |
0.334 |
|
| 2023 |
Bergaggio E, Tai WT, Aroldi A, Mecca C, Landoni E, Nüesch M, Mota I, Metovic J, Molinaro L, Ma L, Alvarado D, Ambrogio C, Voena C, Blasco RB, Li T, ... ... Irvine DJ, et al. ALK inhibitors increase ALK expression and sensitize neuroblastoma cells to ALK.CAR-T cells. Cancer Cell. PMID 38039964 DOI: 10.1016/j.ccell.2023.11.004 |
0.305 |
|
| 2023 |
Phung I, Rodrigues KA, Marina-Zárate E, Maiorino L, Pahar B, Lee WH, Melo M, Kaur A, Allers C, Fahlberg M, Grasperge BF, Dufour JP, Schiro F, Aye PP, Lopez PG, ... ... Irvine DJ, et al. A combined adjuvant approach primes robust germinal center responses and humoral immunity in non-human primates. Nature Communications. 14: 7107. PMID 37925510 DOI: 10.1038/s41467-023-42923-x |
0.359 |
|
| 2023 |
Mandal S, Melo M, Gordiichuk P, Acharya S, Poh YC, Li N, Aung A, Dane EL, Irvine DJ, Kumari S. WASP facilitates tumor mechanosensitivity in T lymphocytes. Biorxiv : the Preprint Server For Biology. PMID 37873483 DOI: 10.1101/2023.10.02.560434 |
0.369 |
|
| 2023 |
Truex NL, Rondon A, Rössler SL, Hanna CC, Cho Y, Wang BY, Backlund CM, Lutz EA, Irvine DJ, Pentelute BL. Enhanced Vaccine Immunogenicity Enabled by Targeted Cytosolic Delivery of Tumor Antigens into Dendritic Cells. Acs Central Science. 9: 1835-1845. PMID 37780364 DOI: 10.1021/acscentsci.3c00625 |
0.382 |
|
| 2023 |
Yousefpour P, Ni K, Irvine DJ. Targeted modulation of immune cells and tissues using engineered biomaterials. Nature Reviews Bioengineering. 1: 107-124. PMID 37772035 DOI: 10.1038/s44222-022-00016-2 |
0.305 |
|
| 2023 |
Truex NL, Mohapatra S, Melo M, Rodriguez J, Li N, Abraham W, Sementa D, Touti F, Keskin DB, Wu CJ, Irvine DJ, Gómez-Bombarelli R, Pentelute BL. Design of Cytotoxic T Cell Epitopes by Machine Learning of Human Degrons. Biorxiv : the Preprint Server For Biology. PMID 37662211 DOI: 10.1101/2023.08.22.554289 |
0.348 |
|
| 2023 |
Nguyen KB, Roerden M, Copeland CJ, Backlund CM, Klop-Packel NG, Remba T, Kim B, Singh NK, Birnbaum ME, Irvine DJ, Spranger S. Decoupled neoantigen cross-presentation by dendritic cells limits anti-tumor immunity against tumors with heterogeneous neoantigen expression. Elife. 12. PMID 37548358 DOI: 10.7554/eLife.85263 |
0.366 |
|
| 2023 |
Mota I, Patrucco E, Mastini C, Mahadevan NR, Thai TC, Bergaggio E, Cheong TC, Leonardi G, Karaca-Atabay E, Campisi M, Poggio T, Menotti M, Ambrogio C, Longo DL, Klaeger S, ... ... Irvine DJ, et al. ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer. Nature Cancer. PMID 37430060 DOI: 10.1038/s43018-023-00591-2 |
0.306 |
|
| 2023 |
Ma L, Hostetler A, Morgan DM, Maiorino L, Sulkaj I, Whittaker CA, Neeser A, Pires IS, Yousefpour P, Gregory J, Qureshi K, Dye J, Abraham W, Suh H, Li N, ... ... Irvine DJ, et al. Vaccine-boosted CAR T crosstalk with host immunity to reject tumors with antigen heterogeneity. Cell. PMID 37413990 DOI: 10.1016/j.cell.2023.06.002 |
0.397 |
|
| 2023 |
Zhang AQ, Hostetler A, Chen LE, Mukkamala V, Abraham W, Padilla LT, Wolff AN, Maiorino L, Backlund CM, Aung A, Melo M, Li N, Wu S, Irvine DJ. Universal redirection of CAR T cells against solid tumours via membrane-inserted ligands for the CAR. Nature Biomedical Engineering. PMID 37291434 DOI: 10.1038/s41551-023-01048-8 |
0.314 |
|
| 2023 |
Bhagchandani SH, Vohidov F, Milling LE, Tong EY, Brown CM, Ramseier ML, Liu B, Fessenden TB, Nguyen HV, Kiel GR, Won L, Langer RS, Spranger S, Shalek AK, Irvine DJ, et al. Engineering kinetics of TLR7/8 agonist release from bottlebrush prodrugs enables tumor-focused immune stimulation. Science Advances. 9: eadg2239. PMID 37075115 DOI: 10.1126/sciadv.adg2239 |
0.388 |
|
| 2023 |
Aung A, Cui A, Maiorino L, Amini AP, Gregory JR, Bukenya M, Zhang Y, Lee H, Cottrell CA, Morgan DM, Silva M, Suh H, Kirkpatrick JD, Amlashi P, Remba T, ... ... Irvine DJ, et al. Low protease activity in B cell follicles promotes retention of intact antigens after immunization. Science (New York, N.Y.). 379: eabn8934. PMID 36701450 DOI: 10.1126/science.abn8934 |
0.347 |
|
| 2022 |
Irvine DJ, Maus MV, Mooney DJ, Wong WW. The future of engineered immune cell therapies. Science (New York, N.Y.). 378: 853-858. PMID 36423279 DOI: 10.1126/science.abq6990 |
0.301 |
|
| 2022 |
Chang JYH, Agarwal Y, Rodrigues KA, Momin N, Ni K, Read BJ, Moyer TJ, Mehta NK, Silva M, Suh H, Melo MB, Wittrup KD, Irvine DJ. Co-Anchoring of Engineered Immunogen and Immunostimulatory Cytokines to Alum Promotes Enhanced-Humoral Immunity. Advanced Therapeutics. 5: 2100235. PMID 36311814 DOI: 10.1002/adtp.202100235 |
0.382 |
|
| 2022 |
Backlund CM, Holden RL, Moynihan KD, Garafola D, Farquhar C, Mehta NK, Maiorino L, Pham S, Iorgulescu JB, Reardon DA, Wu CJ, Pentelute BL, Irvine DJ. Cell-penetrating peptides enhance peptide vaccine accumulation and persistence in lymph nodes to drive immunogenicity. Proceedings of the National Academy of Sciences of the United States of America. 119: e2204078119. PMID 35914154 DOI: 10.1073/pnas.2204078119 |
0.333 |
|
| 2022 |
Hartwell BL, Melo MB, Xiao P, Lemnios AA, Li N, Chang JYH, Yu J, Gebre MS, Chang A, Maiorino L, Carter C, Moyer TJ, Dalvie NC, Rodriguez-Aponte SA, Rodrigues KA, ... ... Irvine DJ, et al. Intranasal vaccination with lipid-conjugated immunogens promotes antigen transmucosal uptake to drive mucosal and systemic immunity. Science Translational Medicine. 14: eabn1413. PMID 35857825 DOI: 10.1126/scitranslmed.abn1413 |
0.313 |
|
| 2022 |
Grace BE, Backlund CM, Morgan DM, Kang BH, Singh NK, Huisman BD, Rappazzo CG, Moynihan KD, Maiorino L, Dobson CS, Kyung T, Gordon KS, Holec PV, Mbah OCT, Garafola D, ... ... Irvine DJ, et al. Identification of Highly Cross-Reactive Mimotopes for a Public T Cell Response in Murine Melanoma. Frontiers in Immunology. 13: 886683. PMID 35812387 DOI: 10.3389/fimmu.2022.886683 |
0.419 |
|
| 2022 |
Dane EL, Belessiotis-Richards A, Backlund C, Wang J, Hidaka K, Milling LE, Bhagchandani S, Melo MB, Wu S, Li N, Donahue N, Ni K, Ma L, Okaniwa M, Stevens MM, ... ... Irvine DJ, et al. STING agonist delivery by tumour-penetrating PEG-lipid nanodiscs primes robust anticancer immunity. Nature Materials. 21: 710-720. PMID 35606429 DOI: 10.1038/s41563-022-01251-z |
0.708 |
|
| 2022 |
Sriram G, Emmons TR, Milling LE, Irvine DJ, Yaffe MB. Immunogenic cell stress and injury versus immunogenic cell death: implications for improving cancer treatment with immune checkpoint blockade. Molecular & Cellular Oncology. 9: 2039038. PMID 35402699 DOI: 10.1080/23723556.2022.2039038 |
0.323 |
|
| 2022 |
Agarwal Y, Milling LE, Chang JYH, Santollani L, Sheen A, Lutz EA, Tabet A, Stinson J, Ni K, Rodrigues KA, Moyer TJ, Melo MB, Irvine DJ, Wittrup KD. Intratumourally injected alum-tethered cytokines elicit potent and safer local and systemic anticancer immunity. Nature Biomedical Engineering. PMID 35013574 DOI: 10.1038/s41551-021-00831-9 |
0.723 |
|
| 2021 |
Wang C, Cui A, Bukenya M, Aung A, Pradhan D, Whittaker CA, Agarwal Y, Thomas A, Liang S, Amlashi P, Suh H, Spranger S, Hacohen N, Irvine DJ. Reprogramming NK cells and macrophages via combined antibody and cytokine therapy primes tumors for elimination by checkpoint blockade. Cell Reports. 37: 110021. PMID 34818534 DOI: 10.1016/j.celrep.2021.110021 |
0.81 |
|
| 2021 |
Milling LE, Garafola D, Agarwal Y, Wu S, Thomas A, Donahue N, Adams J, Thai N, Suh H, Irvine DJ. Neoadjuvant STING activation, extended half-life interleukin-2, and checkpoint blockade promote metastasis clearance via sustained NK-cell activation. Cancer Immunology Research. PMID 34686488 DOI: 10.1158/2326-6066.CIR-21-0247 |
0.305 |
|
| 2021 |
Martin JT, Hartwell BL, Kumarapperuma SC, Melo MB, Carnathan DG, Cossette BJ, Adams J, Gong S, Zhang W, Tokatlian T, Menis S, Schiffner T, Franklin CG, Goins B, Fox PT, ... ... Irvine DJ, et al. Combined PET and whole-tissue imaging of lymphatic-targeting vaccines in non-human primates. Biomaterials. 275: 120868. PMID 34091299 DOI: 10.1016/j.biomaterials.2021.120868 |
0.303 |
|
| 2021 |
Kang BH, Momin N, Moynihan KD, Silva M, Li Y, Irvine DJ, Wittrup KD. Immunotherapy-induced antibodies to endogenous retroviral envelope glycoprotein confer tumor protection in mice. Plos One. 16: e0248903. PMID 33857179 DOI: 10.1371/journal.pone.0248903 |
0.343 |
|
| 2021 |
Rakhra K, Abraham W, Wang C, Moynihan KD, Li N, Donahue N, Baldeon AD, Irvine DJ. Exploiting albumin as a mucosal vaccine chaperone for robust generation of lung-resident memory T cells. Science Immunology. 6. PMID 33741657 DOI: 10.1126/sciimmunol.abd8003 |
0.35 |
|
| 2020 |
Martin JT, Cottrell CA, Antanasijevic A, Carnathan DG, Cossette BJ, Enemuo CA, Gebru EH, Choe Y, Viviano F, Fischinger S, Tokatlian T, Cirelli KM, Ueda G, Copps J, Schiffner T, ... ... Irvine DJ, et al. Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations. Npj Vaccines. 5: 72. PMID 33574310 DOI: 10.1038/s41541-020-00223-1 |
0.322 |
|
| 2020 |
Kato Y, Abbott RK, Freeman BL, Haupt S, Groschel B, Silva M, Menis S, Irvine DJ, Schief WR, Crotty S. Multifaceted Effects of Antigen Valency on B Cell Response Composition and Differentiation In Vivo. Immunity. PMID 32857950 DOI: 10.1016/J.Immuni.2020.08.001 |
0.427 |
|
| 2020 |
Martin JT, Cottrell CA, Antanasijevic A, Carnathan DG, Cossette BJ, Enemuo CA, Gebru EH, Choe Y, Viviano F, Fischinger S, Tokatlian T, Cirelli KM, Ueda G, Copps J, Schiffner T, ... ... Irvine DJ, et al. Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations. Npj Vaccines. 5: 72. PMID 32802411 DOI: 10.1038/s41541-020-00223-1 |
0.322 |
|
| 2020 |
Barberio AE, Smith SG, Correa S, Nguyen C, Nhan B, Melo M, Tokatlian T, Suh H, Irvine DJ, Hammond PT. Cancer Cell Coating Nanoparticles for Optimal Tumor-Specific Cytokine Delivery. Acs Nano. PMID 32692155 DOI: 10.1021/Acsnano.0C03109 |
0.394 |
|
| 2020 |
Andrews LP, Somasundaram A, Moskovitz JM, Szymczak-Workman AL, Liu C, Cillo AR, Lin H, Normolle DP, Moynihan KD, Taniuchi I, Irvine DJ, Kirkwood JM, Lipson EJ, Ferris RL, Bruno TC, et al. Resistance to PD1 blockade in the absence of metalloprotease-mediated LAG3 shedding. Science Immunology. 5. PMID 32680952 DOI: 10.1126/Sciimmunol.Abc2728 |
0.371 |
|
| 2020 |
Veneziano R, Moyer TJ, Stone MB, Wamhoff EC, Read BJ, Mukherjee S, Shepherd TR, Das J, Schief WR, Irvine DJ, Bathe M. Role of nanoscale antigen organization on B-cell activation probed using DNA origami. Nature Nanotechnology. PMID 32601450 DOI: 10.1038/S41565-020-0719-0 |
0.414 |
|
| 2020 |
Irvine DJ, Aung A, Silva M. Controlling timing and location in vaccines. Advanced Drug Delivery Reviews. PMID 32598970 DOI: 10.1016/J.Addr.2020.06.019 |
0.419 |
|
| 2020 |
He Y, Hong C, Yan EZ, Fletcher SJ, Zhu G, Yang M, Li Y, Sun X, Irvine DJ, Li J, Hammond PT. Self-assembled cGAMP-STINGΔTM signaling complex as a bioinspired platform for cGAMP delivery. Science Advances. 6: eaba7589. PMID 32582856 DOI: 10.1126/Sciadv.Aba7589 |
0.362 |
|
| 2020 |
Mehta NK, Pradhan RV, Soleimany AP, Moynihan KD, Rothschilds AM, Momin N, Rakhra K, Mata-Fink J, Bhatia SN, Wittrup KD, Irvine DJ. Pharmacokinetic tuning of protein-antigen fusions enhances the immunogenicity of T-cell vaccines. Nature Biomedical Engineering. PMID 32483299 DOI: 10.1038/S41551-020-0563-4 |
0.438 |
|
| 2020 |
Moyer TJ, Kato Y, Abraham W, Chang JYH, Kulp DW, Watson N, Turner HL, Menis S, Abbott RK, Bhiman JN, Melo MB, Simon HA, Herrera-De la Mata S, Liang S, Seumois G, ... ... Irvine DJ, et al. Author Correction: A Engineered immunogen binding to alum adjuvant enhances humoral immunity. Nature Medicine. 26: 804. PMID 32405059 DOI: 10.1038/S41591-020-0861-0 |
0.318 |
|
| 2020 |
Irvine DJ, Read BJ. Shaping humoral immunity to vaccines through antigen-displaying nanoparticles. Current Opinion in Immunology. 65: 1-6. PMID 32200132 DOI: 10.1016/J.Coi.2020.01.007 |
0.411 |
|
| 2020 |
Moyer TJ, Kato Y, Abraham W, Chang JYH, Kulp DW, Watson N, Turner HL, Menis S, Abbott RK, Bhiman JN, Melo MB, Simon HA, Herrera-De la Mata S, Liang S, Seumois G, ... ... Irvine DJ, et al. Engineered immunogen binding to alum adjuvant enhances humoral immunity. Nature Medicine. PMID 32066977 DOI: 10.1038/S41591-020-0753-3 |
0.468 |
|
| 2020 |
Irvine DJ, Dane EL. Enhancing cancer immunotherapy with nanomedicine. Nature Reviews. Immunology. PMID 32005979 DOI: 10.1038/S41577-019-0269-6 |
0.428 |
|
| 2020 |
Kumari S, Mak M, Poh YC, Tohme M, Watson N, Melo M, Janssen E, Dustin M, Geha R, Irvine DJ. Cytoskeletal tension actively sustains the migratory T-cell synaptic contact. The Embo Journal. e102783. PMID 31894880 DOI: 10.15252/Embj.2019102783 |
0.389 |
|
| 2020 |
Sriram G, Milling L, Chen J, Abraham W, Irvine DJ, Yaffe MB. Intratumoral administration of DNA-damaging chemotherapy-treated tumor cells to enhance therapeutic benefit of systemic immune checkpoint blockade in mouse cancer models. Journal of Clinical Oncology. 38: 77-77. DOI: 10.1200/Jco.2020.38.5_Suppl.77 |
0.442 |
|
| 2019 |
Gilfillan CB, Wang C, Mohsen MO, Rufer N, Hebeisen M, Allard M, Verdeil G, Irvine DJ, Bachmann MF, Speiser DE. Murine CD8 T Cell Functional Avidity is Stable In Vivo but not In Vitro: Independence from Homologous Prime/Boost Time Interval and Antigen Density. European Journal of Immunology. PMID 31785153 DOI: 10.1002/Eji.201948355 |
0.482 |
|
| 2019 |
Mahajan VS, Demissie E, Alsufyani F, Kumari S, Yuen GJ, Viswanadham V, Huang A, Tran JQ, Moon JJ, Irvine DJ, Pillai S. DOCK2 Sets the Threshold for Entry into the Virtual Memory CD8 T Cell Compartment by Negatively Regulating Tonic TCR Triggering. Journal of Immunology (Baltimore, Md. : 1950). PMID 31740487 DOI: 10.4049/Jimmunol.1900440 |
0.42 |
|
| 2019 |
Havenar-Daughton C, Carnathan DG, Boopathy AV, Upadhyay AA, Murrell B, Reiss SM, Enemuo CA, Gebru EH, Choe Y, Dhadvai P, Viviano F, Kaushik K, Bhiman JN, Briney B, Burton DR, ... ... Irvine DJ, et al. Rapid Germinal Center and Antibody Responses in Non-human Primates after a Single Nanoparticle Vaccine Immunization. Cell Reports. 29: 1756-1766.e8. PMID 31722194 DOI: 10.1016/J.Celrep.2019.10.008 |
0.447 |
|
| 2019 |
Kumari S, Colin-York H, Irvine DJ, Fritzsche M. Not All T Cell Synapses Are Built the Same Way. Trends in Immunology. PMID 31645298 DOI: 10.1016/J.It.2019.09.009 |
0.416 |
|
| 2019 |
Loukogeorgakis SP, Fachin CG, Santos Dias A, Li H, Tang L, Kim AG, Vrecenak JD, Stratigis J, Ahn NJ, Nissim I, Nissim I, Moron AF, Martins JL, Peranteau WH, De Coppi P, ... Irvine DJ, et al. Donor-Cell Engineering with GSK3 Inhibitor-Loaded Nanoparticles Enhances Engraftment Following in Utero Transplantation. Blood. PMID 31570489 DOI: 10.1182/Blood.2019001037 |
0.324 |
|
| 2019 |
Melo M, Porter E, Zhang Y, Silva M, Li N, Dobosh B, Liguori A, Skog P, Landais E, Menis S, Sok D, Nemazee D, Schief WR, Weiss R, Irvine DJ. Immunogenicity of RNA Replicons Encoding HIV Env Immunogens Designed for Self-Assembly into Nanoparticles. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 31515132 DOI: 10.1016/J.Ymthe.2019.08.007 |
0.413 |
|
| 2019 |
Boopathy AV, Mandal A, Kulp DW, Menis S, Bennett NR, Watkins HC, Wang W, Martin JT, Thai NT, He Y, Schief WR, Hammond PT, Irvine DJ. Enhancing humoral immunity via sustained-release implantable microneedle patch vaccination. Proceedings of the National Academy of Sciences of the United States of America. PMID 31358641 DOI: 10.1073/Pnas.1902179116 |
0.428 |
|
| 2019 |
Ma L, Dichwalkar T, Chang JYH, Cossette B, Garafola D, Zhang AQ, Fichter M, Wang C, Liang S, Silva M, Kumari S, Mehta NK, Abraham W, Thai N, Li N, ... ... Irvine DJ, et al. Enhanced CAR-T cell activity against solid tumors by vaccine boosting through the chimeric receptor. Science (New York, N.Y.). 365: 162-168. PMID 31296767 DOI: 10.1126/Science.Aav8692 |
0.804 |
|
| 2019 |
Momin N, Mehta NK, Bennett NR, Ma L, Palmeri JR, Chinn MM, Lutz EA, Kang B, Irvine DJ, Spranger S, Wittrup KD. Anchoring of intratumorally administered cytokines to collagen safely potentiates systemic cancer immunotherapy. Science Translational Medicine. 11. PMID 31243150 DOI: 10.1126/Scitranslmed.Aaw2614 |
0.422 |
|
| 2019 |
Escolano A, Gristick HB, Abernathy ME, Merkenschlager J, Gautam R, Oliveira TY, Pai J, West AP, Barnes CO, Cohen AA, Wang H, Golijanin J, Yost D, Keeffe JR, Wang Z, ... ... Irvine DJ, et al. Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques. Nature. PMID 31142836 DOI: 10.1038/S41586-019-1250-Z |
0.4 |
|
| 2019 |
Cirelli KM, Carnathan DG, Nogal B, Martin JT, Rodriguez OL, Upadhyay AA, Enemuo CA, Gebru EH, Choe Y, Viviano F, Nakao C, Pauthner MG, Reiss S, Cottrell CA, Smith ML, ... ... Irvine DJ, et al. Slow Delivery Immunization Enhances HIV Neutralizing Antibody and Germinal Center Responses via Modulation of Immunodominance. Cell. PMID 31080066 DOI: 10.1016/J.Cell.2019.04.012 |
0.462 |
|
| 2019 |
Rothschilds A, Tzeng A, Mehta NK, Moynihan KD, Irvine DJ, Wittrup KD. Order of administration of combination cytokine therapies can decouple toxicity from efficacy in syngeneic mouse tumor models. Oncoimmunology. 8: e1558678. PMID 31069130 DOI: 10.1080/2162402X.2018.1558678 |
0.377 |
|
| 2019 |
Li Y, Teague B, Zhang Y, Su Z, Porter E, Dobosh B, Wagner T, Irvine DJ, Weiss R. In vitro evolution of enhanced RNA replicons for immunotherapy. Scientific Reports. 9: 6932. PMID 31061426 DOI: 10.1038/S41598-019-43422-0 |
0.335 |
|
| 2019 |
Xie YQ, Arik H, Wei L, Zheng Y, Suh H, Irvine DJ, Tang L. Redox-responsive interleukin-2 nanogel specifically and safely promotes the proliferation and memory precursor differentiation of tumor-reactive T-cells. Biomaterials Science. PMID 30698174 DOI: 10.1039/C8Bm01556B |
0.404 |
|
| 2019 |
Irvine D. Material aid for vaccines. Nature Materials. 17: 472-473. PMID 29795221 DOI: 10.1038/S41563-018-0089-2 |
0.329 |
|
| 2019 |
Irvine DJ. Abstract IA37: Enhancing the function of CAR T cells via a universal vaccine strategy Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-Ia37 |
0.49 |
|
| 2019 |
Veneziano R, Moyer T, Stone MB, Kumari S, Schief WR, Bathe M, Irvine D. Probing the Role of HIV Antigen Nanoscale Organization on B-Cell Activation with DNA Origami Biophysical Journal. 116: 578a. DOI: 10.1016/J.Bpj.2018.11.3109 |
0.312 |
|
| 2019 |
Gilfillan CB, Wang C, Mohsen MO, Rufer N, Hebeisen M, Allard M, Verdeil G, Irvine DJ, Bachmann MF, Speiser DE. Author response for "Murine CD8 T Cell Functional Avidity is Stable In Vivo but not In Vitro : Independence from Homologous Prime/Boost Time Interval and Antigen Density" European Journal of Immunology. DOI: 10.1002/Eji.201948355/V2/Response1 |
0.395 |
|
| 2018 |
Tokatlian T, Read BJ, Jones CA, Kulp DW, Menis S, Chang JYH, Steichen JM, Kumari S, Allen JD, Dane EL, Liguori A, Sangesland M, Lingwood D, Crispin M, Schief WR, ... Irvine DJ, et al. Innate immune recognition of glycans targets HIV nanoparticle immunogens to germinal centers. Science (New York, N.Y.). PMID 30573546 DOI: 10.1126/Science.Aat9120 |
0.442 |
|
| 2018 |
Pauthner MG, Nkolola JP, Havenar-Daughton C, Murrell B, Reiss SM, Bastidas R, Prévost J, Nedellec R, von Bredow B, Abbink P, Cottrell CA, Kulp DW, Tokatlian T, Nogal B, Bianchi M, ... ... Irvine DJ, et al. Vaccine-Induced Protection from Homologous Tier 2 SHIV Challenge in Nonhuman Primates Depends on Serum-Neutralizing Antibody Titers. Immunity. PMID 30552025 DOI: 10.1016/J.Immuni.2018.11.011 |
0.395 |
|
| 2018 |
Yang YS, Moynihan KD, Bekdemir A, Dichwalkar TM, Noh MM, Watson N, Melo M, Ingram J, Suh H, Ploegh H, Stellacci FR, Irvine DJ. Targeting small molecule drugs to T cells with antibody-directed cell-penetrating gold nanoparticles. Biomaterials Science. PMID 30444251 DOI: 10.1039/C8Bm01208C |
0.421 |
|
| 2018 |
Mandal A, Boopathy AV, Lam LKW, Moynihan KD, Welch ME, Bennett NR, Turvey ME, Thai N, Van JH, Love JC, Hammond PT, Irvine DJ. Cell and fluid sampling microneedle patches for monitoring skin-resident immunity. Science Translational Medicine. 10. PMID 30429353 DOI: 10.1126/Scitranslmed.Aar2227 |
0.425 |
|
| 2018 |
Mottas I, Bekdemir A, Cereghetti A, Spagnuolo L, Yang YS, Müller M, Irvine DJ, Stellacci F, Bourquin C. Amphiphilic nanoparticle delivery enhances the anticancer efficacy of a TLR7 ligand via local immune activation. Biomaterials. 190: 111-120. PMID 30415018 DOI: 10.1016/J.Biomaterials.2018.10.031 |
0.39 |
|
| 2018 |
Tokatlian T, Kulp DW, Mutafyan AA, Jones CA, Menis S, Georgeson E, Kubitz M, Zhang MH, Melo MB, Silva M, Yun DS, Schief WR, Irvine DJ. Enhancing Humoral Responses Against HIV Envelope Trimers via Nanoparticle Delivery with Stabilized Synthetic Liposomes. Scientific Reports. 8: 16527. PMID 30410003 DOI: 10.1038/S41598-018-34853-2 |
0.578 |
|
| 2018 |
He Y, Hong C, Li J, Howard MT, Li Y, Turvey ME, Uppu DSSM, Martin JR, Zhang K, Irvine DJ, Hammond PT. Synthetic Charge-Invertible Polymer for Rapid and Complete Implantation of Layer-by-Layer Microneedle Drug Films for Enhanced Transdermal Vaccination. Acs Nano. PMID 30272942 DOI: 10.1021/Acsnano.8B05373 |
0.392 |
|
| 2018 |
Badamchi-Zadeh A, Moynihan KD, Larocca RA, Aid M, Provine NM, Iampietro MJ, Kinnear E, Penaloza-MacMaster P, Abbink P, Blass E, Tregoning JS, Irvine DJ, Barouch DH. Combined HDAC and BET Inhibition Enhances Melanoma Vaccine Immunogenicity and Efficacy. Journal of Immunology (Baltimore, Md. : 1950). 201: 2744-2752. PMID 30249811 DOI: 10.4049/Jimmunol.1800885 |
0.45 |
|
| 2018 |
Tang L, Zheng Y, Melo MB, Mabardi L, Castaño AP, Xie YQ, Li N, Kudchodkar SB, Wong HC, Jeng EK, Maus MV, Irvine DJ. Enhancing T cell therapy through TCR-signaling-responsive nanoparticle drug delivery. Nature Biotechnology. PMID 29985479 DOI: 10.1038/Nbt.4181 |
0.483 |
|
| 2018 |
Moynihan KD, Holden RL, Mehta NK, Wang C, Karver MR, Dinter J, Liang S, Abraham W, Melo MB, Zhang AQ, Li N, Le Gall S, Pentelute B, Irvine DJ. Enhancement of peptide vaccine immunogenicity by increasing lymphatic drainage and boosting serum stability. Cancer Immunology Research. PMID 29915023 DOI: 10.1158/2326-6066.Cir-17-0607 |
0.794 |
|
| 2018 |
Zhang Y, Li N, Suh H, Irvine DJ. Nanoparticle anchoring targets immune agonists to tumors enabling anti-cancer immunity without systemic toxicity. Nature Communications. 9: 6. PMID 29295974 DOI: 10.1038/S41467-017-02251-3 |
0.392 |
|
| 2018 |
Irvine DJ. Abstract IA06: Enhancing combination immunotherapy and adoptive cell therapy of cancer via lymph node-targeted vaccines Cancer Immunology Research. 6. DOI: 10.1158/2326-6074.Tumimm17-Ia06 |
0.439 |
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| 2018 |
Sriram G, Milling L, Irvine DJ, Yaffe MB. Abstract B53: Intra-tracheal delivery of low-dose bacterial lipopolysaccharides protects against tumor formation in the KP lung adenocarcinoma model Cancer Immunology Research. 6. DOI: 10.1158/2326-6074.Tumimm17-B53 |
0.376 |
|
| 2017 |
Schmid D, Park CG, Hartl CA, Subedi N, Cartwright AN, Puerto RB, Zheng Y, Maiarana J, Freeman GJ, Wucherpfennig KW, Irvine DJ, Goldberg MS. T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity. Nature Communications. 8: 1747. PMID 29170511 DOI: 10.1038/S41467-017-01830-8 |
0.432 |
|
| 2017 |
Fan Y, Kuai R, Xu Y, Ochyl LJ, Irvine DJ, Moon J. Immunogenic Cell Death Amplified by Co-localized Adjuvant Delivery for Cancer Immunotherapy. Nano Letters. PMID 29144754 DOI: 10.1021/Acs.Nanolett.7B03218 |
0.484 |
|
| 2017 |
Appelbe OK, Moynihan KD, Flor A, Rymut N, Irvine DJ, Kron SJ. Radiation-enhanced delivery of systemically administered amphiphilic-CpG oligodeoxynucleotide. Journal of Controlled Release : Official Journal of the Controlled Release Society. 266: 248-255. PMID 28987882 DOI: 10.1016/J.Jconrel.2017.09.043 |
0.416 |
|
| 2017 |
Janssen E, Kumari S, Tohme M, Ullas S, Barrera V, Tas JM, Castillo-Rama M, Bronson RT, Usmani SM, Irvine DJ, Mempel TR, Geha RS. DOCK8 enforces immunological tolerance by promoting IL-2 signaling and immune synapse formation in Tregs. Jci Insight. 2. PMID 28978806 DOI: 10.1172/Jci.Insight.94298 |
0.351 |
|
| 2017 |
Moynihan KD, Irvine DJ. Roles for Innate Immunity in Combination Immunotherapies. Cancer Research. 77: 5215-5221. PMID 28928130 DOI: 10.1158/0008-5472.Can-17-1340 |
0.39 |
|
| 2017 |
Fotoran WL, Santangelo R, de Miranda BNM, Irvine DJ, Wunderlich G. DNA-Loaded Cationic Liposomes Efficiently Function as a Vaccine against Malarial Proteins. Molecular Therapy. Methods & Clinical Development. 7: 1-10. PMID 28879213 DOI: 10.1016/J.Omtm.2017.08.004 |
0.405 |
|
| 2017 |
Pauthner M, Havenar-Daughton C, Sok D, Nkolola JP, Bastidas R, Boopathy AV, Carnathan DG, Chandrashekar A, Cirelli KM, Cottrell CA, Eroshkin AM, Guenaga J, Kaushik K, Kulp DW, Liu J, ... ... Irvine DJ, et al. Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches. Immunity. 46: 1073-1088.e6. PMID 28636956 DOI: 10.1016/J.Immuni.2017.05.007 |
0.417 |
|
| 2017 |
Milling L, Zhang Y, Irvine DJ. Delivering safer immunotherapies for cancer. Advanced Drug Delivery Reviews. 114: 79-101. PMID 28545888 DOI: 10.1016/J.Addr.2017.05.011 |
0.365 |
|
| 2017 |
Zheng Y, Tang L, Mabardi L, Kumari S, Irvine DJ. Enhancing Adoptive Cell Therapy of Cancer through Targeted Delivery of Small-Molecule Immunomodulators to Internalizing or Non-Internalizing Receptors. Acs Nano. PMID 28231431 DOI: 10.1021/Acsnano.7B00078 |
0.442 |
|
| 2017 |
Khademhosseini A, Chan WW, Chhowalla M, Glotzer SC, Gogotsi Y, Hafner JH, Hammond PT, Hersam MC, Javey A, Kagan CR, Kotov NA, Lee ST, Li Y, Möhwald H, Mulvaney PA, ... ... Irvine DJ, et al. Nanoscience and Nanotechnology Cross Borders. Acs Nano. PMID 28199099 DOI: 10.1021/Acsnano.7B00953 |
0.447 |
|
| 2017 |
Yang YS, Atukorale PU, Moynihan KD, Bekdemir A, Rakhra K, Tang L, Stellacci F, Irvine DJ. High-throughput quantitation of inorganic nanoparticle biodistribution at the single-cell level using mass cytometry. Nature Communications. 8: 14069. PMID 28094297 DOI: 10.1038/Ncomms14069 |
0.365 |
|
| 2017 |
Hanson MC, Irvine DJ. Synthesis of Lymph Node-Targeting Adjuvants. Methods in Molecular Biology (Clifton, N.J.). 1494: 145-152. PMID 27718191 DOI: 10.1007/978-1-4939-6445-1_10 |
0.356 |
|
| 2017 |
Badamchi-Zadeh A, Moynihan KD, Provine NM, Larocca R, Irvine DJ, Barouch DH. Combined HDAC and BET inhibition to enhance cancer vaccine-elicited T-cell responses. Journal of Clinical Oncology. 35: e14632-e14632. DOI: 10.1200/Jco.2017.35.15_Suppl.E14632 |
0.465 |
|
| 2017 |
Irvine DJ. Abstract IA15: Engineering combination immunotherapy agents for synergistic innate and adaptive immune attack on solid tumors Cancer Immunology Research. 5. DOI: 10.1158/2326-6074.Tumimm16-Ia15 |
0.45 |
|
| 2017 |
Zhang Y, Irvine DJ. Abstract A87: Nanoparticle-mediated systemic delivery of immune agonists to tumors enabling anti-tumor efficacy without toxicity Cancer Immunology Research. 5. DOI: 10.1158/2326-6074.Tumimm16-A87 |
0.404 |
|
| 2017 |
Moynihan KD, Opel C, Szeto G, Tzeng A, Eric Z, Engreitz J, Robert W, Rakhra K, Zhang M, Rothschilds A, Kumari S, Kelly RL, Kwan B, Abraham W, Hu K, ... ... Irvine DJ, et al. Abstract A52: Eradication of large established tumors with combination immunotherapy engaging innate and adaptive immunity Cancer Immunology Research. 5. DOI: 10.1158/2326-6074.Tumimm16-A52 |
0.775 |
|
| 2017 |
Rakhra K, Zhu EF, Abraham W, Moynihan KD, Mehta N, Wittrup KD, Irvine DJ. Abstract A42: Combination immunotherapy of an autochthonous murine lung cancer model expressing human CEA as a tumor-associated self-antigen Cancer Immunology Research. 5. DOI: 10.1158/2326-6074.Tumimm16-A42 |
0.396 |
|
| 2017 |
Kumari S, Moynihan K, Irvine DJ. Abstract A25: High-resolution visualization of immune response across the intact melanoma tumor Cancer Immunology Research. 5. DOI: 10.1158/2326-6074.Tumimm16-A25 |
0.414 |
|
| 2017 |
Tang L, Zheng Y, Mabardi L, Irvine D. Abstract B53: T lymphocyte engineering with responsive cytokine nanogels for enhanced efficacy and safety of adoptive cell therapy for cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Epso16-B53 |
0.456 |
|
| 2016 |
Griffiths KL, Ahmed M, Das S, Gopal R, Horne W, Connell TD, Moynihan KD, Kolls JK, Irvine DJ, Artyomov MN, Rangel-Moreno J, Khader SA. Targeting dendritic cells to accelerate T-cell activation overcomes a bottleneck in tuberculosis vaccine efficacy. Nature Communications. 7: 13894. PMID 28004802 DOI: 10.1038/Ncomms13894 |
0.427 |
|
| 2016 |
Jones RB, Mueller S, Kumari S, Vrbanac V, Genel S, Tager AM, Allen TM, Walker BD, Irvine DJ. Antigen recognition-triggered drug delivery mediated by nanocapsule-functionalized cytotoxic T-cells. Biomaterials. 117: 44-53. PMID 27936416 DOI: 10.1016/J.Biomaterials.2016.11.048 |
0.444 |
|
| 2016 |
Tzeng A, Kauke MJ, Zhu EF, Moynihan KD, Opel CF, Yang NJ, Mehta N, Kelly RL, Szeto GL, Overwijk WW, Irvine DJ, Wittrup KD. Temporally Programmed CD8α(+) DC Activation Enhances Combination Cancer Immunotherapy. Cell Reports. 17: 2503-2511. PMID 27926855 DOI: 10.1016/J.Celrep.2016.11.020 |
0.74 |
|
| 2016 |
Moynihan KD, Opel CF, Szeto GL, Tzeng A, Zhu EF, Engreitz JM, Williams RT, Rakhra K, Zhang MH, Rothschilds AM, Kumari S, Kelly RL, Kwan BH, Abraham W, Hu K, ... ... Irvine DJ, et al. Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses. Nature Medicine. PMID 27775706 DOI: 10.1038/Nm.4200 |
0.798 |
|
| 2016 |
Tam HH, Melo MB, Kang M, Pelet JM, Ruda VM, Foley MH, Hu JK, Kumari S, Crampton J, Baldeon AD, Sanders RW, Moore JP, Crotty S, Langer R, Anderson DG, ... ... Irvine DJ, et al. Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination. Proceedings of the National Academy of Sciences of the United States of America. PMID 27702895 DOI: 10.1073/Pnas.1606050113 |
0.528 |
|
| 2016 |
Steichen JM, Kulp DW, Tokatlian T, Escolano A, Dosenovic P, Stanfield RL, McCoy LE, Ozorowski G, Hu X, Kalyuzhniy O, Briney B, Schiffner T, Garces F, Freund NT, Gitlin AD, ... ... Irvine DJ, et al. HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies. Immunity. PMID 27617678 DOI: 10.1016/J.Immuni.2016.08.016 |
0.394 |
|
| 2016 |
Janssen E, Tohme M, Hedayat M, Leick M, Kumari S, Ramesh N, Massaad MJ, Ullas S, Azcutia V, Goodnow CC, Randall KL, Qiao Q, Wu H, Al-Herz W, Cox D, ... ... Irvine DJ, et al. A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton. The Journal of Clinical Investigation. PMID 27599296 DOI: 10.1172/Jci85774 |
0.359 |
|
| 2016 |
Donius LR, Cheng Y, Choi J, Sun ZJ, Hanson M, Zhang M, Gierahn TM, Marquez S, Uduman M, Kleinstein SH, Irvine D, Love JC, Reinherz EL, Kim M. Generation of long-lived bone marrow plasma cells secreting antibodies specific for HIV-1 gp41 MPER in the absence of polyreactivity. Journal of Virology. PMID 27466419 DOI: 10.1128/Jvi.01089-16 |
0.584 |
|
| 2016 |
Jones RB, Mueller S, O'Connor R, Rimpel K, Sloan DD, Karel D, Wong HC, Jeng EK, Thomas AS, Whitney JB, Lim SY, Kovacs C, Benko E, Karandish S, Huang SH, ... ... Irvine DJ, et al. A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4+ T-Cells to Recognition by Cytotoxic T-Lymphocytes. Plos Pathogens. 12: e1005545. PMID 27082643 DOI: 10.1371/Journal.Ppat.1005545 |
0.41 |
|
| 2016 |
Moyer TJ, Zmolek AC, Irvine DJ. Beyond antigens and adjuvants: formulating future vaccines. The Journal of Clinical Investigation. 126: 799-808. PMID 26928033 DOI: 10.1172/Jci81083 |
0.457 |
|
| 2016 |
Kimmerling RJ, Lee Szeto G, Li JW, Genshaft AS, Kazer SW, Payer KR, de Riba Borrajo J, Blainey PC, Irvine DJ, Shalek AK, Manalis SR. A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages. Nature Communications. 7: 10220. PMID 26732280 DOI: 10.1038/Ncomms10220 |
0.381 |
|
| 2016 |
Zhu EF, Rakhra K, Mehta N, Moynihan KD, Opel CF, Irvine DJ, Wittrup KD. Abstract B120: Characterization and combination immunotherapy treatment of an inducible autochthonous murine lung cancer model expressing human carcinoembryonic antigen (CEA) as a tumor-associated self-antigen Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-B120 |
0.442 |
|
| 2016 |
Tang L, Zheng Y, Mabardi L, Irvine DJ. Abstract A073: Carrier-free delivery of cytokine to specifically expand adoptively transferred T cells for enhanced cancer immunotherapy Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-A073 |
0.464 |
|
| 2016 |
Sharei A, Gilbert J, Irvine D, Jensen K, Langer R. Abstract 2293: Vector-free engineering of immune cells for adoptive cell therapy Cancer Research. 76: 2293-2293. DOI: 10.1158/1538-7445.Am2016-2293 |
0.582 |
|
| 2016 |
Irvine DJ. Materializing the future of vaccines and immunotherapy Nature Reviews Materials. 1. DOI: 10.1038/Natrevmats.2015.8 |
0.355 |
|
| 2015 |
Dane EL, Irvine DJ. Big thinking for adjuvants Nature Biotechnology. 33: 1146-1148. PMID 26544144 DOI: 10.1038/Nbt.3398 |
0.311 |
|
| 2015 |
Arnold KB, Szeto GL, Alter G, Irvine DJ, Lauffenburger DA. CD4+ T cell-dependent and CD4+ T cell-independent cytokine-chemokine network changes in the immune responses of HIV-infected individuals. Science Signaling. 8: ra104. PMID 26486173 DOI: 10.1126/Scisignal.Aab0808 |
0.764 |
|
| 2015 |
Hotaling NA, Tang L, Irvine DJ, Babensee JE. Biomaterial Strategies for Immunomodulation. Annual Review of Biomedical Engineering. PMID 26421896 DOI: 10.1146/Annurev-Bioeng-071813-104814 |
0.437 |
|
| 2015 |
Mehta NK, Moynihan KD, Irvine DJ. Engineering New Approaches to Cancer Vaccines. Cancer Immunology Research. 3: 836-43. PMID 26156157 DOI: 10.1158/2326-6066.Cir-15-0112 |
0.449 |
|
| 2015 |
Irvine DJ, Hanson MC, Rakhra K, Tokatlian T. Synthetic Nanoparticles for Vaccines and Immunotherapy. Chemical Reviews. 115: 11109-46. PMID 26154342 DOI: 10.1021/Acs.Chemrev.5B00109 |
0.512 |
|
| 2015 |
Huang B, Abraham WD, Zheng Y, Bustamante López SC, Luo SS, Irvine DJ. Active targeting of chemotherapy to disseminated tumors using nanoparticle-carrying T cells. Science Translational Medicine. 7: 291ra94. PMID 26062846 DOI: 10.1126/Scitranslmed.Aaa5447 |
0.454 |
|
| 2015 |
Lee Szeto G, Van Egeren D, Worku H, Sharei A, Alejandro B, Park C, Frew K, Brefo M, Mao S, Heimann M, Langer R, Jensen K, Irvine DJ. Microfluidic squeezing for intracellular antigen loading in polyclonal B-cells as cellular vaccines. Scientific Reports. 5: 10276. PMID 25999171 DOI: 10.1038/Srep10276 |
0.542 |
|
| 2015 |
Hanson MC, Crespo MP, Abraham W, Moynihan KD, Szeto GL, Chen SH, Melo MB, Mueller S, Irvine DJ. Nanoparticulate STING agonists are potent lymph node-targeted vaccine adjuvants. The Journal of Clinical Investigation. 125: 2532-46. PMID 25938786 DOI: 10.1172/Jci79915 |
0.753 |
|
| 2015 |
Zhu EF, Gai SA, Opel CF, Kwan BH, Surana R, Mihm MC, Kauke MJ, Moynihan KD, Angelini A, Williams RT, Stephan MT, Kim JS, Yaffe MB, Irvine DJ, Weiner LM, et al. Synergistic innate and adaptive immune response to combination immunotherapy with anti-tumor antigen antibodies and extended serum half-life IL-2. Cancer Cell. 27: 489-501. PMID 25873172 DOI: 10.1016/J.Ccell.2015.03.004 |
0.468 |
|
| 2015 |
Liu H, Irvine DJ. Guiding principles in the design of molecular bioconjugates for vaccine applications. Bioconjugate Chemistry. 26: 791-801. PMID 25822926 DOI: 10.1021/Acs.Bioconjchem.5B00103 |
0.409 |
|
| 2015 |
Kumari S, Depoil D, Martinelli R, Judokusumo E, Carmona G, Gertler FB, Kam LC, Carman CV, Burkhardt JK, Irvine DJ, Dustin ML. Actin foci facilitate activation of the phospholipase C-γ in primary T lymphocytes via the WASP pathway. Elife. 4. PMID 25758716 DOI: 10.7554/Elife.04953 |
0.302 |
|
| 2015 |
Wang S, Mata-Fink J, Kriegsman B, Hanson M, Irvine DJ, Eisen HN, Burton DR, Wittrup KD, Kardar M, Chakraborty AK. Manipulating the selection forces during affinity maturation to generate cross-reactive HIV antibodies. Cell. 160: 785-97. PMID 25662010 DOI: 10.1016/J.Cell.2015.01.027 |
0.359 |
|
| 2015 |
Hanson MC, Abraham W, Crespo MP, Chen SH, Liu H, Szeto GL, Kim M, Reinherz EL, Irvine DJ. Liposomal vaccines incorporating molecular adjuvants and intrastructural T-cell help promote the immunogenicity of HIV membrane-proximal external region peptides. Vaccine. 33: 861-8. PMID 25559188 DOI: 10.1016/J.Vaccine.2014.12.045 |
0.747 |
|
| 2015 |
Castellarnau M, Szeto GL, Su HW, Tokatlian T, Love JC, Irvine DJ, Voldman J. Stochastic particle barcoding for single-cell tracking and multiparametric analysis. Small (Weinheim An Der Bergstrasse, Germany). 11: 489-98. PMID 25180800 DOI: 10.1002/Smll.201401369 |
0.707 |
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| 2015 |
Kumari S, Depoil D, Martinelli R, Judokusumo E, Carmona G, Gertler FB, Kam LC, Carman CV, Burkhardt JK, Irvine DJ, Dustin ML. Author response: Actin foci facilitate activation of the phospholipase C-γ in primary T lymphocytes via the WASP pathway Elife. DOI: 10.7554/Elife.04953.034 |
0.317 |
|
| 2015 |
Tang L, Zheng Y, Mabardi L, Irvine DJ. T lymphocyte engineering with cytokine nanogels for enhanced cancer immunotherapy Journal For Immunotherapy of Cancer. 3. DOI: 10.1186/2051-1426-3-S2-P54 |
0.445 |
|
| 2015 |
Zhang Y, Irvine DJ. Systemic delivery of liposome-anchored anti-CD137 and IL2-Fc prevents lethal toxicity and elicits potent antitumor immunity Journal For Immunotherapy of Cancer. 3. DOI: 10.1186/2051-1426-3-S2-P318 |
0.347 |
|
| 2015 |
Li AV, Eby JK, DeMuth PC, Irvine DJ. Abstract LB-227: Novel synthetic vesicle for rapid in vivo expansion of CD8 T cells can significantly improve checkpoint inhibitor therapy Immunology. 75. DOI: 10.1158/1538-7445.Am2015-Lb-227 |
0.356 |
|
| 2015 |
Kudchodkar SB, Tang L, Jeng EK, Wong HC, Irvine DJ, Maus MV. 517. Improving CAR T Cell Efficacy for Solid Tumors By Nanogel-Based Delivery of Immunomodulatory Proteins Molecular Therapy. 23: S207. DOI: 10.1016/S1525-0016(16)34126-0 |
0.452 |
|
| 2014 |
Yang YS, Carney RP, Stellacci F, Irvine DJ. Enhancing radiotherapy by lipid nanocapsule-mediated delivery of amphiphilic gold nanoparticles to intracellular membranes. Acs Nano. 8: 8992-9002. PMID 25123510 DOI: 10.1021/Nn502146R |
0.335 |
|
| 2014 |
Jones RB, O'Connor R, Mueller S, Foley M, Szeto GL, Karel D, Lichterfeld M, Kovacs C, Ostrowski MA, Trocha A, Irvine DJ, Walker BD. Histone deacetylase inhibitors impair the elimination of HIV-infected cells by cytotoxic T-lymphocytes. Plos Pathogens. 10: e1004287. PMID 25122219 DOI: 10.1371/Journal.Ppat.1004287 |
0.716 |
|
| 2014 |
Pejawar-Gaddy S, Kovacs JM, Barouch DH, Chen B, Irvine DJ. Design of lipid nanocapsule delivery vehicles for multivalent display of recombinant Env trimers in HIV vaccination. Bioconjugate Chemistry. 25: 1470-8. PMID 25020048 DOI: 10.1021/Bc5002246 |
0.399 |
|
| 2014 |
Hanson MC, Bershteyn A, Crespo MP, Irvine DJ. Antigen delivery by lipid-enveloped PLGA microparticle vaccines mediated by in situ vesicle shedding Biomacromolecules. 15: 2475-2481. PMID 24894061 DOI: 10.1021/Bm500337R |
0.385 |
|
| 2014 |
Foley MH, Forcier T, McAndrew E, Gonzalez M, Chen H, Juelg B, Walker BD, Irvine DJ. High avidity CD8+ T cells efficiently eliminate motile HIV-infected targets and execute a locally focused program of anti-viral function. Plos One. 9: e87873. PMID 24551068 DOI: 10.1371/Journal.Pone.0087873 |
0.389 |
|
| 2014 |
Liu H, Moynihan KD, Zheng Y, Szeto GL, Li AV, Huang B, Van Egeren DS, Park C, Irvine DJ. Structure-based programming of lymph-node targeting in molecular vaccines. Nature. 507: 519-22. PMID 24531764 DOI: 10.1038/Nature12978 |
0.726 |
|
| 2014 |
DeMuth PC, Min Y, Irvine DJ, Hammond PT. Implantable silk composite microneedles for programmable vaccine release kinetics and enhanced immunogenicity in transcutaneous immunization. Advanced Healthcare Materials. 3: 47-58. PMID 23847143 DOI: 10.1002/Adhm.201300139 |
0.434 |
|
| 2014 |
Loukogeorgakis SP, Li H, Tang L, Kim AG, Vrecenak JD, Nissim I, Conner MA, Nissim I, De Coppi P, Peranteau W, Irvine DJ, Flake AW. Cell Engineering with Glycogen Synthase Kinase-3 Beta Inhibitor-Loaded Synthetic Nanoparticles Enhances Hematopoietic Engraftment of Bone Marrow Mononuclear Cells Following in Utero Transplantation Blood. 124: 2414-2414. DOI: 10.1182/Blood.V124.21.2414.2414 |
0.354 |
|
| 2014 |
Tang L, Zheng Y, Irvine DJ. Abstract 2792: Engineering T lymphocytes with protein nanogels for cancer immunotherapy Cancer Research. 74: 2792-2792. DOI: 10.1158/1538-7445.Am2014-2792 |
0.457 |
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| 2014 |
DeMuth PC, Min Y, Irvine DJ, Hammond PT. Drug Delivery: Implantable Silk Composite Microneedles for Programmable Vaccine Release Kinetics and Enhanced Immunogenicity in Transcutaneous Immunization (Adv. Healthcare Mater. 1/2014) Advanced Healthcare Materials. 3: 1-1. DOI: 10.1002/Adhm.201470001 |
0.355 |
|
| 2013 |
Drake A, Joshi NS, Szeto GL, Zhu E, Eisen HN, Irvine DJ. Koch Institute Symposium on Cancer Immunology and Immunotherapy. Cancer Immunology Research. 1: 217-222. PMID 24466562 DOI: 10.1158/2326-6066.Cir-13-0116 |
0.72 |
|
| 2013 |
DeMuth PC, Li AV, Abbink P, Liu J, Li H, Stanley KA, Smith KM, Lavine CL, Seaman MS, Kramer JA, Miller AD, Abraham W, Suh H, Elkhader J, Hammond PT, ... ... Irvine DJ, et al. Vaccine delivery with microneedle skin patches in nonhuman primates. Nature Biotechnology. 31: 1082-5. PMID 24316643 DOI: 10.1038/Nbt.2759 |
0.303 |
|
| 2013 |
Irvine DJ, Swartz MA, Szeto GL. Engineering synthetic vaccines using cues from natural immunity. Nature Materials. 12: 978-90. PMID 24150416 DOI: 10.1038/Nmat3775 |
0.771 |
|
| 2013 |
Li AV, Moon JJ, Abraham W, Suh H, Elkhader J, Seidman MA, Yen M, Im EJ, Foley MH, Barouch DH, Irvine DJ. Generation of effector memory T cell-based mucosal and systemic immunity with pulmonary nanoparticle vaccination. Science Translational Medicine. 5: 204ra130. PMID 24068737 DOI: 10.1126/Scitranslmed.3006516 |
0.496 |
|
| 2013 |
Kim M, Song L, Moon J, Sun ZY, Bershteyn A, Hanson M, Cain D, Goka S, Kelsoe G, Wagner G, Irvine D, Reinherz EL. Immunogenicity of membrane-bound HIV-1 gp41 membrane-proximal external region (MPER) segments is dominated by residue accessibility and modulated by stereochemistry. The Journal of Biological Chemistry. 288: 31888-901. PMID 24047898 DOI: 10.1074/Jbc.M113.494609 |
0.377 |
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| 2013 |
Zheng Y, Stephan MT, Gai SA, Abraham W, Shearer A, Irvine DJ. In vivo targeting of adoptively transferred T-cells with antibody- and cytokine-conjugated liposomes Journal of Controlled Release. 172: 426-435. PMID 23770010 DOI: 10.1016/J.Jconrel.2013.05.037 |
0.49 |
|
| 2013 |
Demuth PC, Garcia-Beltran WF, Ai-Ling ML, Hammond PT, Irvine DJ. Composite dissolving microneedles for coordinated control of antigen and adjuvant delivery kinetics in transcutaneous vaccination. Advanced Functional Materials. 23: 161-172. PMID 23503923 DOI: 10.1002/Adfm.201201512 |
0.373 |
|
| 2013 |
Ackerman ME, Dugast AS, McAndrew EG, Tsoukas S, Licht AF, Irvine DJ, Alter G. Enhanced phagocytic activity of HIV-specific antibodies correlates with natural production of immunoglobulins with skewed affinity for FcγR2a and FcγR2b. Journal of Virology. 87: 5468-76. PMID 23468489 DOI: 10.1128/Jvi.03403-12 |
0.384 |
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| 2013 |
Su X, Yang N, Wittrup KD, Irvine DJ. Synergistic antitumor activity from two-stage delivery of targeted toxins and endosome-disrupting nanoparticles. Biomacromolecules. 14: 1093-102. PMID 23444913 DOI: 10.1021/Bm3019906 |
0.384 |
|
| 2013 |
Kwong B, Gai SA, Elkhader J, Wittrup KD, Irvine DJ. Localized immunotherapy via liposome-anchored Anti-CD137 + IL-2 prevents lethal toxicity and elicits local and systemic antitumor immunity. Cancer Research. 73: 1547-58. PMID 23436794 DOI: 10.1158/0008-5472.Can-12-3343 |
0.439 |
|
| 2013 |
Wang Y, Irvine DJ. Convolution of chemoattractant secretion rate, source density, and receptor desensitization direct diverse migration patterns in leukocytes Integrative Biology (United Kingdom). 5: 481-494. PMID 23392181 DOI: 10.1039/C3Ib20249F |
0.379 |
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| 2013 |
DeMuth PC, Min Y, Huang B, Kramer JA, Miller AD, Barouch DH, Hammond PT, Irvine DJ. Polymer multilayer tattooing for enhanced DNA vaccination. Nature Materials. 12: 367-76. PMID 23353628 DOI: 10.1038/Nmat3550 |
0.396 |
|
| 2013 |
Mata-Fink J, Kriegsman B, Yu HX, Zhu H, Hanson MC, Irvine DJ, Wittrup KD. Rapid conformational epitope mapping of anti-gp120 antibodies with a designed mutant panel displayed on yeast. Journal of Molecular Biology. 425: 444-56. PMID 23159556 DOI: 10.1016/J.Jmb.2012.11.010 |
0.303 |
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| 2013 |
Verma A, Uzun O, Hu Y, Hu Y, Han H, Watson N, Chen S, Irvine DJ, Stellacci F. Erratum: Surface-structure-regulated cell-membrane penetration by monolayer-protected nanoparticles Nature Materials. 12: 376-376. DOI: 10.1038/Nmat3593 |
0.3 |
|
| 2013 |
DeMuth PC, Garcia-Beltran WF, Ai-Ling ML, Hammond PT, Irvine DJ. Drug Delivery: Composite Dissolving Microneedles for Coordinated Control of Antigen and Adjuvant Delivery Kinetics in Transcutaneous Vaccination (Adv. Funct. Mater. 2/2013) Advanced Functional Materials. 23: 138-138. DOI: 10.1002/Adfm.201370008 |
0.359 |
|
| 2012 |
Yamanaka YJ, Szeto GL, Gierahn TM, Forcier TL, Benedict KF, Brefo MS, Lauffenburger DA, Irvine DJ, Love JC. Cellular barcodes for efficiently profiling single-cell secretory responses by microengraving. Analytical Chemistry. 84: 10531-6. PMID 23205933 DOI: 10.1021/Ac302264Q |
0.752 |
|
| 2012 |
DeMuth PC, Moon JJ, Suh H, Hammond PT, Irvine DJ. Releasable layer-by-layer assembly of stabilized lipid nanocapsules on microneedles for enhanced transcutaneous vaccine delivery. Acs Nano. 6: 8041-51. PMID 22920601 DOI: 10.1021/Nn302639R |
0.407 |
|
| 2012 |
Moon JJ, Huang B, Irvine DJ. Engineering Nano- and microparticles to tune immunity Advanced Materials. 24: 3724-3746. PMID 22641380 DOI: 10.1002/Adma.201200446 |
0.415 |
|
| 2012 |
Stephan MT, Stephan SB, Bak P, Chen J, Irvine DJ. Synapse-directed delivery of immunomodulators using T-cell-conjugated nanoparticles Biomaterials. 33: 5776-5787. PMID 22594972 DOI: 10.1016/J.Biomaterials.2012.04.029 |
0.454 |
|
| 2012 |
Moon JJ, Suh H, Polhemus ME, Ockenhouse CF, Yadava A, Irvine DJ. Antigen-displaying lipid-enveloped PLGA nanoparticles as delivery agents for a Plasmodium vivax malaria vaccine. Plos One. 7: e31472. PMID 22328935 DOI: 10.1371/Journal.Pone.0031472 |
0.394 |
|
| 2012 |
Moon JJ, Suh H, Li AV, Ockenhouse CF, Yadava A, Irvine DJ. Enhancing humoral responses to a malaria antigen with nanoparticle vaccines that expand Tfh cells and promote germinal center induction. Proceedings of the National Academy of Sciences of the United States of America. 109: 1080-5. PMID 22247289 DOI: 10.1073/Pnas.1112648109 |
0.476 |
|
| 2012 |
Metallo CM, Gameiro PA, Bell EL, Mattaini KR, Yang J, Hiller K, Jewell CM, Johnson ZR, Irvine DJ, Guarente L, Kelleher JK, Vander Heiden MG, Iliopoulos O, Stephanopoulos G. Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia Nature. 481: 380-384. PMID 22101433 DOI: 10.1038/Nature10602 |
0.549 |
|
| 2012 |
Bershteyn A, Hanson MC, Crespo MP, Moon JJ, Li AV, Suh H, Irvine DJ. Robust IgG responses to nanograms of antigen using a biomimetic lipid-coated particle vaccine. Journal of Controlled Release : Official Journal of the Controlled Release Society. 157: 354-65. PMID 21820024 DOI: 10.1016/J.Jconrel.2011.07.029 |
0.42 |
|
| 2012 |
Mata-Fink J, Hanson M, Kriegsman B, Irvine D, Wittrup K. Engineered gp120 immunogens that elicit VRC01-like antibodies by vaccination Retrovirology. 9. DOI: 10.1186/1742-4690-9-S2-P6 |
0.362 |
|
| 2012 |
DeMuth P, Huang B, Min Y, Barouch D, Hammond P, Irvine D. Engineered microneedle arrays for transcutaneous HIV vaccine delivery Retrovirology. 9. DOI: 10.1186/1742-4690-9-S2-P334 |
0.359 |
|
| 2012 |
Hanson M, Mata-Fink J, Abraham W, Wittrup K, Irvine D. Shaping humoral responses against mini-libraries of HIV env antigens via lipid nanoparticle vaccine delivery Retrovirology. 9: 1-1. DOI: 10.1186/1742-4690-9-S2-O63 |
0.411 |
|
| 2012 |
Pejawar-Gaddy S, Kovacs J, Barouch D, Chen B, Irvine D. Design of lipid nanoparticle delivery agents for multivalent display of recombinant Env trimers in HIV vaccination Retrovirology. 9. DOI: 10.1186/1742-4690-9-S2-O10 |
0.419 |
|
| 2011 |
Jewell CM, Jung JM, Atukorale PU, Carney RP, Stellacci F, Irvine DJ. Oligonucleotide delivery by cell-penetrating "striped" nanoparticles. Angewandte Chemie (International Ed. in English). 50: 12312-5. PMID 22028047 DOI: 10.1002/Anie.201104514 |
0.558 |
|
| 2011 |
Jewell CM, Bustamante Lo?ez SC, Irvine DJ. In situ engineering of the lymph node microenvironment via intranodal injection of adjuvant-releasing polymer particles Proceedings of the National Academy of Sciences of the United States of America. 108: 15745-15750. PMID 21896725 DOI: 10.1073/Pnas.1105200108 |
0.658 |
|
| 2011 |
Stephan MT, Irvine DJ. Enhancing Cell therapies from the Outside In: Cell Surface Engineering Using Synthetic Nanomaterials. Nano Today. 6: 309-325. PMID 21826117 DOI: 10.1016/J.Nantod.2011.04.001 |
0.375 |
|
| 2011 |
MartÃnez-MartÃn N, Fernández-Arenas E, Cemerski S, Delgado P, Turner M, Heuser J, Irvine DJ, Huang B, Bustelo XR, Shaw A, Alarcón B. T cell receptor internalization from the immunological synapse is mediated by TC21 and RhoG GTPase-dependent phagocytosis. Immunity. 35: 208-22. PMID 21820331 DOI: 10.1016/J.Immuni.2011.06.003 |
0.395 |
|
| 2011 |
Liu H, Kwong B, Irvine DJ. Membrane anchored immunostimulatory oligonucleotides for in vivo cell modification and localized immunotherapy. Angewandte Chemie (International Ed. in English). 50: 7052-5. PMID 21688362 DOI: 10.1002/Anie.201101266 |
0.43 |
|
| 2011 |
De Temmerman ML, Rejman J, Demeester J, Irvine DJ, Gander B, De Smedt SC. Particulate vaccines: On the quest for optimal delivery and immune response Drug Discovery Today. 16: 569-582. PMID 21570475 DOI: 10.1016/J.Drudis.2011.04.006 |
0.417 |
|
| 2011 |
Kwong B, Liu H, Irvine DJ. Induction of potent anti-tumor responses while eliminating systemic side effects via liposome-anchored combinatorial immunotherapy. Biomaterials. 32: 5134-47. PMID 21514665 DOI: 10.1016/J.Biomaterials.2011.03.067 |
0.367 |
|
| 2011 |
Melvin AT, Welf ES, Wang Y, Irvine DJ, Haugh JM. In chemotaxing fibroblasts, both high-fidelity and weakly biased cell movements track the localization of PI3K signaling. Biophysical Journal. 100: 1893-901. PMID 21504725 DOI: 10.1016/J.Bpj.2011.02.047 |
0.329 |
|
| 2011 |
Irvine DJ. Drug delivery: One nanoparticle, one kill Nature Materials. 10: 342-343. PMID 21499312 DOI: 10.1038/Nmat3014 |
0.356 |
|
| 2011 |
Wang Y, Irvine DJ. Engineering chemoattractant gradients using chemokine-releasing polysaccharide microspheres Biomaterials. 32: 4903-4913. PMID 21463892 DOI: 10.1016/J.Biomaterials.2011.03.027 |
0.413 |
|
| 2011 |
Su X, Fricke J, Kavanagh DG, Irvine DJ. In vitro and in vivo mRNA delivery using lipid-enveloped pH-responsive polymer nanoparticles Molecular Pharmaceutics. 8: 774-787. PMID 21417235 DOI: 10.1021/Mp100390W |
0.322 |
|
| 2011 |
Palmer MJ, Mahajan VS, Chen J, Irvine DJ, Lauffenburger DA. Signaling thresholds govern heterogeneity in IL-7-receptor-mediated responses of naïve CD8(+) T cells. Immunology and Cell Biology. 89: 581-94. PMID 21339767 DOI: 10.1038/Icb.2011.5 |
0.497 |
|
| 2011 |
Moon JJ, Suh H, Bershteyn A, Stephan MT, Liu H, Huang B, Sohail M, Luo S, Um SH, Khant H, Goodwin JT, Ramos J, Chiu W, Irvine DJ. Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses. Nature Materials. 10: 243-51. PMID 21336265 DOI: 10.1038/Nmat2960 |
0.455 |
|
| 2011 |
Ackerman ME, Moldt B, Wyatt RT, Dugast AS, McAndrew E, Tsoukas S, Jost S, Berger CT, Sciaranghella G, Liu Q, Irvine DJ, Burton DR, Alter G. A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples. Journal of Immunological Methods. 366: 8-19. PMID 21192942 DOI: 10.1016/J.Jim.2010.12.016 |
0.359 |
|
| 2011 |
Huang B, Irvine DJ. Abstract 4432: Cell-mediated chemotherapeutic drug nanoparticle delivery to lymphoma tumors Cancer Research. 71: 4432-4432. DOI: 10.1158/1538-7445.Am2011-4432 |
0.452 |
|
| 2010 |
DeMuth PC, Su X, Samuel RE, Hammond PT, Irvine DJ. Nano-layered microneedles for transcutaneous delivery of polymer nanoparticles and plasmid DNA. Advanced Materials (Deerfield Beach, Fla.). 22: 4851-6. PMID 20859938 DOI: 10.1002/Adma.201001525 |
0.343 |
|
| 2010 |
Stephan MT, Moon JJ, Um SH, Bersthteyn A, Irvine DJ. Therapeutic cell engineering with surface-conjugated synthetic nanoparticles Nature Medicine. 16: 1035-1041. PMID 20711198 DOI: 10.1038/Nm.2198 |
0.419 |
|
| 2010 |
Swiston AJ, Gilbert JB, Irvine DJ, Cohen RE, Rubner MF. Freely suspended cellular "backpacks" lead to cell aggregate self-assembly. Biomacromolecules. 11: 1826-32. PMID 20527876 DOI: 10.1021/Bm100305H |
0.371 |
|
| 2010 |
Stephan M, Moon JJ, Um SH, Bershteyn A, Irvine DJ. Abstract SSY01-05: Therapeutic cell engineering using surface-conjugated synthetic nanoparticles Immunology. DOI: 10.1158/1538-7445.Am10-Ssy01-05 |
0.312 |
|
| 2010 |
Fricke J, Seung E, Vassor V, Tager AM, Gandhi RT, Walker B, Irvine D, Kavanagh D. Synthetic mRNA-loaded Nanoparticles Elicit Mucosal IL-17+ and IFNγ+ T Cells Clinical Immunology. 135: S137. DOI: 10.1016/J.Clim.2010.03.416 |
0.326 |
|
| 2009 |
Su X, Kim BS, Kim SR, Hammond PT, Irvine DJ. Layer-by-layer-assembled multilayer films for transcutaneous drug and vaccine delivery. Acs Nano. 3: 3719-29. PMID 19824655 DOI: 10.1021/Nn900928U |
0.324 |
|
| 2009 |
Hori Y, Stern PJ, Hynes RO, Irvine DJ. Engulfing tumors with synthetic extracellular matrices for cancer immunotherapy. Biomaterials. 30: 6757-67. PMID 19766305 DOI: 10.1016/J.Biomaterials.2009.08.037 |
0.382 |
|
| 2009 |
Maldonado RA, Soriano MA, Perdomo LC, Sigrist K, Irvine DJ, Decker T, Glimcher LH. Control of T helper cell differentiation through cytokine receptor inclusion in the immunological synapse. The Journal of Experimental Medicine. 206: 877-92. PMID 19349465 DOI: 10.1084/Jem.20082900 |
0.361 |
|
| 2009 |
Hu Y, Atukorale PU, Lu JJ, Moon JJ, Um SH, Cho EC, Wang Y, Chen J, Irvine DJ. Cytosolic delivery mediated via electrostatic surface binding of protein, virus, or siRNA cargos to pH-responsive core-shell gel particles. Biomacromolecules. 10: 756-65. PMID 19239276 DOI: 10.1021/Bm801199Z |
0.348 |
|
| 2009 |
Hori Y, Winans AM, Irvine DJ. Modular injectable matrices based on alginate solution/microsphere mixtures that gel in situ and co-deliver immunomodulatory factors Acta Biomaterialia. 5: 969-982. PMID 19117820 DOI: 10.1016/J.Actbio.2008.11.019 |
0.311 |
|
| 2008 |
Swiston AJ, Cheng C, Um SH, Irvine DJ, Cohen RE, Rubner MF. Surface functionalization of living cells with multilayer patches. Nano Letters. 8: 4446-53. PMID 19367972 DOI: 10.1021/Nl802404H |
0.388 |
|
| 2008 |
Hori Y, Winans AM, Huang CC, Horrigan EM, Irvine DJ. Injectable dendritic cell-carrying alginate gels for immunization and immunotherapy Biomaterials. 29: 3671-3682. PMID 18565578 DOI: 10.1016/J.Biomaterials.2008.05.033 |
0.459 |
|
| 2008 |
Verma A, Uzun O, Hu Y, Hu Y, Han HS, Watson N, Chen S, Irvine DJ, Stellacci F. Surface-structure-regulated cell-membrane penetration by monolayer-protected nanoparticles. Nature Materials. 7: 588-95. PMID 18500347 DOI: 10.1038/Nmat2202 |
0.306 |
|
| 2008 |
Palmer MJ, Mahajan VS, Trajman LC, Irvine DJ, Lauffenburger DA, Chen J. Interleukin-7 receptor signaling network: an integrated systems perspective. Cellular & Molecular Immunology. 5: 79-89. PMID 18445337 DOI: 10.1038/Cmi.2008.10 |
0.457 |
|
| 2008 |
Irvine DJ, Stachowiak AN, Hori Y. Lymphoid tissue engineering: Invoking lymphoid tissue neogenesis in immunotherapy and models of immunity Seminars in Immunology. 20: 137-146. PMID 18035552 DOI: 10.1016/J.Smim.2007.10.010 |
0.316 |
|
| 2008 |
Stachowiak AN, Irvine DJ. Inverse opal hydrogel-collagen composite scaffolds as a supportive microenvironment for immune cell migration Journal of Biomedical Materials Research - Part A. 85: 815-828. PMID 17937415 DOI: 10.1002/Jbm.A.31661 |
0.441 |
|
| 2007 |
Yuhua H, Litwin T, Nagaraja AR, Kwong B, Katz J, Watson N, Irvine DJ. Cytosolic delivery of membrane-impermeable molecules in dendritic cells using pH-responsive core-shell nanoparticles Nano Letters. 7: 3056-3064. PMID 17887715 DOI: 10.1021/Nl071542I |
0.351 |
|
| 2007 |
Irvine DJ, Doh J, Huang B. Patterned surfaces as tools to study ligand recognition and synapse formation by T cells Current Opinion in Immunology. 19: 463-469. PMID 17616382 DOI: 10.1016/J.Coi.2007.05.003 |
0.421 |
|
| 2007 |
Irvine DJ, Doh J. Synthetic surfaces as artificial antigen presenting cells in the study of T cell receptor triggering and immunological synapse formation Seminars in Immunology. 19: 245-254. PMID 17398113 DOI: 10.1016/J.Smim.2007.02.011 |
0.433 |
|
| 2006 |
Stachowiak AN, Wang Y, Huang YC, Irvine DJ. Homeostatic lymphoid chemokines synergize with adhesion ligands to trigger T and B lymphocyte chemokinesis. Journal of Immunology (Baltimore, Md. : 1950). 177: 2340-8. PMID 16887995 DOI: 10.4049/Jimmunol.177.4.2340 |
0.437 |
|
| 2006 |
Doh J, Irvine DJ. Immunological synapse arrays: Patterned protein surfaces that modulate immunological synapse structure formation in T cells Proceedings of the National Academy of Sciences of the United States of America. 103: 5700-5705. PMID 16585528 DOI: 10.1073/Pnas.0509404103 |
0.418 |
|
| 2006 |
Kim H, Cohen RE, Hammond PT, Irvine DJ. Live lymphocyte arrays for biosensing Advanced Functional Materials. 16: 1313-1323. DOI: 10.1002/Adfm.200500888 |
0.427 |
|
| 2005 |
Jain S, Yap WT, Irvine DJ. Synthesis of protein-loaded hydrogel particles in an aqueous two-phase system for coincident antigen and CpG oligonucleotide delivery to antigen-presenting cells Biomacromolecules. 6: 2590-2600. PMID 16153096 DOI: 10.1021/Bm0503221 |
0.372 |
|
| 2005 |
Greenland JR, Liu H, Berry D, Anderson DG, Kim WK, Irvine DJ, Langer R, Letvin NL. Beta-amino ester polymers facilitate in vivo DNA transfection and adjuvant plasmid DNA immunization. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 164-70. PMID 15963932 DOI: 10.1016/J.Ymthe.2005.01.021 |
0.431 |
|
| 2005 |
Zhao X, Jain S, Benjamin Larman H, Gonzalez S, Irvine DJ. Directed cell migration via chemoattractants released from degradable microspheres. Biomaterials. 26: 5048-63. PMID 15769541 DOI: 10.1016/J.Biomaterials.2004.12.003 |
0.415 |
|
| 2004 |
Maldonade RA, Irvine DJ, Schreiber R, Glimcher LH. A role for the immunological synapse in lineage commitment of CD4 lymphocytes Nature. 431: 527-532. PMID 15386021 DOI: 10.1038/Nature02916 |
0.352 |
|
| 2004 |
Li QJ, Dinner AR, Qi S, Irvine DJ, Huppa JB, Davis MM, Chakraborty AK. CD4 enhances T cell sensitivity to antigen by coordinating Lck accumulation at the immunological synapse. Nature Immunology. 5: 791-9. PMID 15247914 DOI: 10.1038/Ni1095 |
0.418 |
|
| 2004 |
Kim H, Doh J, Irvine DJ, Cohen RE, Hammond PT. Large area two-dimensional B cell arrays for sensing and cell-sorting applications. Biomacromolecules. 5: 822-7. PMID 15132667 DOI: 10.1021/Bm034341R |
0.316 |
|
| 2004 |
Purbhoo MA, Irvine DJ, Huppa JB, Davis MM. T cell killing does not require the formation of a stable mature immunological synapse Nature Immunology. 5: 524-530. PMID 15048111 DOI: 10.1038/Ni1058 |
0.419 |
|
| 2004 |
Purbhoo MA, Irvine DJ, Huppa JB, Davis MM. Erratum: Corrigendum: T cell killing does not require the formation of a stable mature immunological synapse Nature Immunology. 5: 658-658. DOI: 10.1038/Ni0604-658A |
0.364 |
|
| 2003 |
Irvine DJ. Function-specific variations in the immunological synapses formed by cytotoxic T cells Proceedings of the National Academy of Sciences of the United States of America. 100: 13739-13740. PMID 14623966 DOI: 10.1073/Pnas.2536626100 |
0.474 |
|
| 2003 |
Davis MM, Krogsgaard M, Huppa JB, Sumen C, Purbhoo MA, Irvine DJ, Wu LC, Ehrlich L. Dynamics of cell surface molecules during T cell recognition. Annual Review of Biochemistry. 72: 717-42. PMID 14527326 DOI: 10.1146/Annurev.Biochem.72.121801.161625 |
0.46 |
|
| 2003 |
Irvine DJ, Stachowiak A, Jain S. Engineering Biomaterials for Control of Immune Cell Functions Materials Science Forum. 3213-3218. DOI: 10.4028/Www.Scientific.Net/Msf.426-432.3213 |
0.362 |
|
| 2002 |
Moss WC, Irvine DJ, Davis MM, Krummel MF. Quantifying signaling-induced reorientation of T cell receptors during immunological synapse formation. Proceedings of the National Academy of Sciences of the United States of America. 99: 15024-9. PMID 12415110 DOI: 10.1073/Pnas.192573999 |
0.399 |
|
| 2002 |
Irvine DJ, Purbhoo MA, Krogsgaard M, Davis MM. Direct observation of ligand recognition by T cells. Nature. 419: 845-9. PMID 12397360 DOI: 10.1038/Nature01076 |
0.447 |
|
| 2002 |
Koo LY, Irvine DJ, Mayes AM, Lauffenburger DA, Griffith LG. Co-regulation of cell adhesion by nanoscale RGD organization and mechanical stimulus. Journal of Cell Science. 115: 1423-33. PMID 11896190 |
0.587 |
|
| 2002 |
Irvine DJ, Hue KA, Mayes AM, Griffith LG. Simulations of cell-surface integrin binding to nanoscale-clustered adhesion ligands. Biophysical Journal. 82: 120-32. PMID 11751301 DOI: 10.1016/S0006-3495(02)75379-4 |
0.513 |
|
| 2001 |
Irvine DJ, Ruzette AV, Mayes AM, Griffith LG. Nanoscale clustering of RGD peptides at surfaces using comb polymers. 2. Surface segregation of comb polymers in polylactide. Biomacromolecules. 2: 545-56. PMID 11749219 DOI: 10.1021/Bm015510F |
0.519 |
|
| 2001 |
Irvine DJ, Mayes AM, Griffith LG. Nanoscale clustering of RGD peptides at surfaces using Comb polymers. 1. Synthesis and characterization of Comb thin films. Biomacromolecules. 2: 85-94. PMID 11749159 DOI: 10.1021/Bm005584B |
0.512 |
|
| 2000 |
Banerjee P, Irvine DJ, Mayes AM, Griffith LG. Polymer latexes for cell-resistant and cell-interactive surfaces. Journal of Biomedical Materials Research. 50: 331-9. PMID 10737874 DOI: 10.1002/(Sici)1097-4636(20000605)50:3<331::Aid-Jbm6>3.0.Co;2-T |
0.545 |
|
| 1998 |
Irvine DJ, Mayes AM, Satija SK, Barker JG, Sofia-Allgor SJ, Griffith LG. Comparison of tethered star and linear poly(ethylene oxide) for control of biomaterials surface properties. Journal of Biomedical Materials Research. 40: 498-509. PMID 9570083 DOI: 10.1002/(Sici)1097-4636(19980605)40:3<498::Aid-Jbm21>3.0.Co;2-E |
0.489 |
|
| 1998 |
Mayes AM, Irvine DJ, Griffith LG. Tailoring polymer surfaces for controlled cell behavior Materials Research Society Symposium - Proceedings. 530: 73-84. DOI: 10.1557/Proc-530-73 |
0.512 |
|
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