| Year |
Citation |
Score |
| 2022 |
du Chatinier A, Meel MH, Das AI, Metselaar DS, Waranecki P, Bugiani M, Breur M, Simonds EF, Lu ED, Weiss WA, Garcia Vallejo JJ, Hoving EW, Phoenix TN, Hulleman E. Generation of immunocompetent syngeneic allograft mouse models for pediatric diffuse midline glioma. Neuro-Oncology Advances. 4: vdac079. PMID 35733514 DOI: 10.1093/noajnl/vdac079 |
0.447 |
|
| 2021 |
Simonds EF, Lu ED, Badillo O, Karimi S, Liu EV, Tamaki W, Rancan C, Downey KM, Stultz J, Sinha M, McHenry LK, Nasholm NM, Chuntova P, Sundström A, Genoud V, et al. Deep immune profiling reveals targetable mechanisms of immune evasion in immune checkpoint inhibitor-refractory glioblastoma. Journal For Immunotherapy of Cancer. 9. PMID 34083417 DOI: 10.1136/jitc-2020-002181 |
0.669 |
|
| 2019 |
McKinney A, Lindberg OR, Engler JR, Chen KY, Kumar A, Gong H, Lu KV, Simonds EF, Cloughesy TF, Liau LM, Prados M, Bollen AW, Berger MS, Shieh JTC, James CD, et al. Mechanisms of resistance to EGFR inhibition reveal metabolic vulnerabilities in human GBM. Molecular Cancer Therapeutics. PMID 31270152 DOI: 10.1158/1535-7163.Mct-18-1330 |
0.703 |
|
| 2019 |
Hartmann FJ, Simonds EF, Vivanco N, Bruce T, Borges L, Nolan GP, Spitzer MH, Bendall SC. Scalable Conjugation and Characterization of Immunoglobulins with Stable Mass Isotope Reporters for Single-Cell Mass Cytometry Analysis. Methods in Molecular Biology (Clifton, N.J.). 1989: 55-81. PMID 31077099 DOI: 10.1007/978-1-4939-9454-0_5 |
0.455 |
|
| 2019 |
Wang W, Grossauer S, Koeck K, Simonds E, Lu E, Bergers G, Weiss W, Petritsch C. Tmod-03. Gaining A Mechanistic Understanding Of Therapy Evasion From Dual Mapk Pathway Inhibition In A Syngeneic Brafv600E Mutant Cdkn2A Deleted Mouse Model To Preempt Resistance In Patients With Brafv600E Mutant Pediatric Glioma Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz036.242 |
0.509 |
|
| 2019 |
Menard M, McHenry L, Nasholm N, Wong-Michalak S, Lu E, Simonds E, Gustafson WC, Weiss WA. Immu-06. Investigating Immunosuppressive Mechanisms In The Tumor Microenvironment Of High-Risk Neuroblastoma; An Immunocompetent, Mycn-Driven, Non-Germline Gem Model Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz036.127 |
0.691 |
|
| 2018 |
Andor N, Simonds EF, Czerwinski DK, Chen J, Grimes SM, Wood-Bouwens C, Zheng GXY, Kubit MA, Greer S, Weiss WA, Levy R, Ji HP. Single-cell RNA-Seq of lymphoma cancers reveals malignant B cell types and co-expression of T cell immune checkpoints. Blood. PMID 30591526 DOI: 10.1182/Blood-2018-08-862292 |
0.567 |
|
| 2018 |
Hartmann FJ, Simonds EF, Bendall SC. A Universal Live Cell Barcoding-Platform for Multiplexed Human Single Cell Analysis. Scientific Reports. 8: 10770. PMID 30018331 DOI: 10.1038/S41598-018-28791-2 |
0.398 |
|
| 2018 |
Aghaeepour N, Simonds EF, Knapp DJHF, Bruggner R, Sachs K, Culos A, Gherardini PF, Samusik N, Fragiadakis G, Bendall S, Gaudilliere B, Angst MS, Eaves CJ, Weiss WA, Fantl W, et al. GateFinder: Projection-based Gating Strategy Optimization for Flow and Mass Cytometry. Bioinformatics (Oxford, England). PMID 29850785 DOI: 10.1093/Bioinformatics/Bty430 |
0.601 |
|
| 2018 |
Good Z, Sarno J, Jager A, Samusik N, Aghaeepour N, Simonds EF, White L, Lacayo NJ, Fantl WJ, Fazio G, Gaipa G, Biondi A, Tibshirani R, Bendall SC, Nolan GP, et al. Single-cell developmental classification of B cell precursor acute lymphoblastic leukemia at diagnosis reveals predictors of relapse. Nature Medicine. PMID 29505032 DOI: 10.1016/J.Exphem.2018.06.027 |
0.565 |
|
| 2018 |
Simonds E, Lu E, McHenry L, Chuntova P, Okada H, Weiss W, Hellstrom M. Immu-04. Overcoming Immune Evasion In Glioblastoma Neuro-Oncology. 20. DOI: 10.1093/Neuonc/Noy148.507 |
0.464 |
|
| 2017 |
Fan Q, Aksoy O, Wong RA, Ilkhanizadeh S, Novotny CJ, Gustafson WC, Truong AY, Cayanan G, Simonds EF, Haas-Kogan D, Phillips JJ, Nicolaides T, Okaniwa M, Shokat KM, Weiss WA. A Kinase Inhibitor Targeted to mTORC1 Drives Regression in Glioblastoma. Cancer Cell. 31: 424-435. PMID 28292440 DOI: 10.1016/J.Ccell.2017.01.014 |
0.749 |
|
| 2017 |
Andor N, Simonds E, Chen J, Wood C, Grimes S, Czerwinski D, Zheng G, Levy R, Ji HP. Abstract 3693: Single cell RNA-Seq of primary lymphomas reveals the diverse transcriptional states of the cancer immunologic milieu Cancer Research. 77: 3693-3693. DOI: 10.1158/1538-7445.Am2017-3693 |
0.417 |
|
| 2017 |
Simonds E, Cayanan G, Park J, Bendall S, Nolan G, Weiss W. STEM-22. Single-cell mass cytometry of human glioblastoma reveals phenotypic heterogeneity and distinct cell cycle and epigenetic states among glioma stem cells Neuro-Oncology. 19: vi230-vi230. DOI: 10.1093/Neuonc/Nox168.937 |
0.624 |
|
| 2017 |
Simonds E, Aghaeepour N, Cayanan G, Park J, Nolan G, Weiss W. HGG-21. IDENTIFICATION OF SMALL MOLECULE KINASE INHIBITORS WITH SPECIFIC ACTIVITY IN PEDIATRIC GLIOMA Neuro-Oncology. 19: iv27-iv27. DOI: 10.1093/Neuonc/Nox083.110 |
0.679 |
|
| 2016 |
Gerhard DS, Clemons PA, Shamji AF, Hon C, Wagner BK, Schreiber SL, Krasnitz A, Sordella R, Sander C, Lowe SW, Powers S, Smith K, Aburi M, Iavarone A, Lasorella A, ... ... Simonds EF, et al. Transforming Big Data into cancer-relevant insight: An initial, multi-tier approach to assess reproducibility and relevance. Molecular Cancer Research : McR. PMID 27401613 DOI: 10.1158/1541-7786.Mcr-16-0090 |
0.678 |
|
| 2016 |
Jones C, Karajannis MA, Jones DT, Kieran MW, Monje M, Baker SJ, Becher OJ, Cho YJ, Gupta N, Hawkins C, Hargrave D, Haas-Kogan DA, Jabado N, Li XN, Mueller S, ... ... Simonds EF, et al. Pediatric high-grade glioma: biologically and clinically in need of new thinking. Neuro-Oncology. PMID 27282398 DOI: 10.1093/Neuonc/Now101 |
0.714 |
|
| 2016 |
Andor N, Simonds E, Chen J, Grimes S, Wood C, Czerwinski DK, Handy C, Levy R, Ji HP. Massively Parallel Single Cell RNA-Seq of Primary Lymphomas Reveals Distinct Cellular Lineages and Diverse, Intratumoral Transcriptional States Blood. 128: 1090-1090. DOI: 10.1182/Blood.V128.22.1090.1090 |
0.399 |
|
| 2015 |
Levine JH, Simonds EF, Bendall SC, Davis KL, Amir ED, Tadmor MD, Litvin O, Fienberg HG, Jager A, Zunder ER, Finck R, Gedman AL, Radtke I, Downing JR, Pe'er D, et al. Data-Driven Phenotypic Dissection of AML Reveals Progenitor-like Cells that Correlate with Prognosis. Cell. PMID 26095251 DOI: 10.1016/J.Cell.2015.05.047 |
0.561 |
|
| 2015 |
Levine JH, Simonds EF, Bendall SC, Nolan GP, Pe'er D. Abstract A32: Computational dissection of phenotypic and functional heterogeneity in acute myeloid leukemia. Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Hemmal14-A32 |
0.577 |
|
| 2015 |
Simonds EF, Nolan GP, Weiss WA. Abstract 2313: Characterizing intratumoral cellular heterogeneity in human glioblastoma xenografts by 30+ parameter single-cell mass cytometry Cancer Research. 75: 2313-2313. DOI: 10.1158/1538-7445.Am2015-2313 |
0.679 |
|
| 2014 |
Gustafson WC, Meyerowitz JG, Nekritz EA, Chen J, Benes C, Charron E, Simonds EF, Seeger R, Matthay KK, Hertz NT, Eilers M, Shokat KM, Weiss WA. Drugging MYCN through an allosteric transition in Aurora kinase A. Cancer Cell. 26: 414-27. PMID 25175806 DOI: 10.1016/J.Ccr.2014.07.015 |
0.749 |
|
| 2014 |
Bendall SC, Davis KL, Amir el-AD, Tadmor MD, Simonds EF, Chen TJ, Shenfeld DK, Nolan GP, Pe'er D. Single-cell trajectory detection uncovers progression and regulatory coordination in human B cell development. Cell. 157: 714-25. PMID 24766814 DOI: 10.1016/J.Cell.2014.04.005 |
0.553 |
|
| 2014 |
Davis KL, Samusik N, Jager A, Bendall SC, Simonds EF, Fantl WJ, Nolan GP. Single Cell Developmental Classification of B Cell Precursor Acute Lymphoblastic Leukemia (BCP ALL) Reveals Link Between Phenotype, Signaling, and Drug Response Blood. 124: 488-488. DOI: 10.1182/Blood.V124.21.488.488 |
0.566 |
|
| 2014 |
Gustafson WC, Meyerowitz JG, Nekritz EA, Charron EA, Chanthery Y, Simonds E, Matthay K, Hertz N, Shokat K, Weiss WA. Abstract 2688: Drugging MYCN through an allosteric transition in Aurora A kinase Cancer Research. 74: 2688-2688. DOI: 10.1158/1538-7445.Am2014-2688 |
0.731 |
|
| 2013 |
Amir el-AD, Davis KL, Tadmor MD, Simonds EF, Levine JH, Bendall SC, Shenfeld DK, Krishnaswamy S, Nolan GP, Pe'er D. viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia. Nature Biotechnology. 31: 545-52. PMID 23685480 DOI: 10.1038/Nbt.2594 |
0.516 |
|
| 2013 |
Finck R, Simonds EF, Jager A, Krishnaswamy S, Sachs K, Fantl W, Pe'er D, Nolan GP, Bendall SC. Normalization of mass cytometry data with bead standards. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 83: 483-94. PMID 23512433 DOI: 10.1002/Cyto.A.22271 |
0.505 |
|
| 2013 |
Amir ED, Litvin O, Levine J, Bendall SC, Davis KL, Simonds EF, Schild T, Rocco M, Rosen N, Nolan GP, Pe'er D. Abstract IA30: Towards rationale therapy: Dealing with intertumor and intratumor heterogeneity Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-Ia30 |
0.631 |
|
| 2013 |
Simonds EF, Bendall SC, Gedman AL, Levine JH, Davis KL, Fienberg HG, Jager A, Amir ED, Radtke I, Fantl WJ, Pe'er D, Downing JR, Nolan GP. Abstract 3178: Deep sequencing of immunophenotypically distinct subsets in acute myeloid leukemia reveals reservoirs of genetically distinct subclones along a conserved differentiation trajectory. Cancer Research. 73: 3178-3178. DOI: 10.1158/1538-7445.Am2013-3178 |
0.551 |
|
| 2012 |
Bodenmiller B, Zunder ER, Finck R, Chen TJ, Savig ES, Bruggner RV, Simonds EF, Bendall SC, Sachs K, Krutzik PO, Nolan GP. Multiplexed mass cytometry profiling of cellular states perturbed by small-molecule regulators. Nature Biotechnology. 30: 858-67. PMID 22902532 DOI: 10.1038/Nbt.2317 |
0.753 |
|
| 2012 |
Linderman MD, Bjornson Z, Simonds EF, Qiu P, Bruggner RV, Sheode K, Meng TH, Plevritis SK, Nolan GP. CytoSPADE: high-performance analysis and visualization of high-dimensional cytometry data. Bioinformatics (Oxford, England). 28: 2400-1. PMID 22782546 DOI: 10.1093/Bioinformatics/Bts425 |
0.477 |
|
| 2012 |
Fienberg HG, Simonds EF, Fantl WJ, Nolan GP, Bodenmiller B. A platinum-based covalent viability reagent for single-cell mass cytometry. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 81: 467-75. PMID 22577098 DOI: 10.1002/Cyto.A.22067 |
0.5 |
|
| 2012 |
Fisher DA, Simonds EF, Behbehani GK, Nolan GP, Bendall SC, Oh ST. Single Cell Mass Cytometry of Dysregulated Signaling Networks in Myeloproliferative Neoplasms and Secondary Acute Myeloid Leukemia Blood. 120: 703-703. DOI: 10.1182/Blood.V120.21.703.703 |
0.615 |
|
| 2012 |
Bendall SC, Amir ED, Tadmor M, Davis KL, Simonds EF, Shenfeld D, Levine J, Nolan GP, Pe'er D. Dimensionality Reduction Reveals Distinct Shapes of Normal and Malignant Hematopoietic Cell Populations Blood. 120: 1451-1451. DOI: 10.1182/Blood.V120.21.1451.1451 |
0.569 |
|
| 2012 |
Sachs K, Nolan GP, Fantl WJ, Simonds EF, Bendall SC, Davis KL. Network-Based Discovery of Prognostic Markers in Pediatric AML by Multi-Dimensional Single Cell Mass Cytometry Blood. 120: 1411-1411. DOI: 10.1182/Blood.V120.21.1411.1411 |
0.545 |
|
| 2012 |
Davis KL, Bendall SC, Amir ED, Simonds EF, Jager A, Trejo A, Pe'er D, Nolan GP. Single Cell Trajectory Detection Orders Hallmarks of Early Human B Cell Development Blood. 120: 1044-1044. DOI: 10.1182/Blood.V120.21.1044.1044 |
0.561 |
|
| 2011 |
Qiu P, Simonds EF, Bendall SC, Gibbs KD, Bruggner RV, Linderman MD, Sachs K, Nolan GP, Plevritis SK. Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE. Nature Biotechnology. 29: 886-91. PMID 21964415 DOI: 10.1038/Nbt.1991 |
0.541 |
|
| 2011 |
Bendall SC, Simonds EF, Qiu P, Amir el-AD, Krutzik PO, Finck R, Bruggner RV, Melamed R, Trejo A, Ornatsky OI, Balderas RS, Plevritis SK, Sachs K, Pe'er D, Tanner SD, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science (New York, N.Y.). 332: 687-96. PMID 21551058 DOI: 10.1126/Science.1198704 |
0.761 |
|
| 2011 |
Davis KL, Simonds EF, Bendall SC, Fantl WJ, Nolan GP. Mass Cytometry Organizes the Heterogeneity of Pediatric B Cell Acute Lymphoblastic Leukemia Blood. 118: 753-753. DOI: 10.1182/Blood.V118.21.753.753 |
0.576 |
|
| 2011 |
Simonds EF, Bendall SC, Davis KL, Fienberg HG, Finck RL, Amir ED, Radtke I, Downing JR, Pe'er D, Nolan GP. Signaling and Immunophenotypic Diversity in Pediatric Acute Myeloid Leukemia As Defined by 31-Parameter Single-Cell Mass Cytometry Blood. 118: 2565-2565. DOI: 10.1182/Blood.V118.21.2565.2565 |
0.614 |
|
| 2010 |
O'Gorman WE, Sampath P, Simonds EF, Sikorski R, O'Malley M, Krutzik PO, Chen H, Panchanathan V, Chaudhri G, Karupiah G, Lewis DB, Thorne SH, Nolan GP. Alternate mechanisms of initial pattern recognition drive differential immune responses to related poxviruses. Cell Host & Microbe. 8: 174-85. PMID 20709294 DOI: 10.1016/J.Chom.2010.07.008 |
0.717 |
|
| 2010 |
Oh ST, Simonds EF, Jones C, Hale MB, Goltsev Y, Gibbs KD, Merker JD, Zehnder JL, Nolan GP, Gotlib J. Novel mutations in the inhibitory adaptor protein LNK drive JAK-STAT signaling in patients with myeloproliferative neoplasms. Blood. 116: 988-92. PMID 20404132 DOI: 10.1182/Blood-2010-02-270108 |
0.55 |
|
| 2010 |
Oh ST, Zahn JM, Jones CD, Zhang B, Loh ML, Kantarjian H, Simonds EF, Bruggner RV, Abidi P, Natsoulis G, Bell J, Buenrostro J, Nolan GP, Zehnder JL, Ji HP, et al. Identification of Novel LNK Mutations In Patients with Chronic Myeloproliferative Neoplasms and Related Disorders Blood. 116: 315-315. DOI: 10.1182/Blood.V116.21.315.315 |
0.499 |
|
| 2010 |
Gotlib J, Zhang B, Jones CD, Riess J, Wong WB, Simonds EF, Hale MB, Abidi P, McClung J, Nolan GP, Oh ST, Zehnder JL. Identification of a Novel Splice Donor Mutation In the Thrombopoietin Gene In a Philippine Family with Hereditary Thrombocythemia Blood. 116: 3086-3086. DOI: 10.1182/Blood.V116.21.3086.3086 |
0.48 |
|
| 2010 |
Davis KL, Simonds EF, Bendall S, Nolan GP. High-Dimensional Analysis of Intracellular Signaling and Dasatinib Inhibition In High-Risk Pediatric Leukemia by 31-Parameter Mass Cytometry Blood. 116: 2761-2761. DOI: 10.1182/Blood.V116.21.2761.2761 |
0.613 |
|
| 2010 |
Oh ST, Simonds EF, Jones C, Hale MB, Goltsev Y, Gibbs KD, Merker JD, Zehnder JL, Nolan GP, Gotlib J. Abstract 239: Mutation of the inhibitory adaptor protein LNK drives potentiated JAK-STAT signaling in patients with JAK2 V617F-negative myeloproliferative neoplasms Cancer Research. 70: 239-239. DOI: 10.1158/1538-7445.Am10-239 |
0.549 |
|
| 2010 |
Oh ST, Zahn JM, Simonds EF, Bell J, Natsoulis G, Buenstro J, Jones C, Hale MB, Goltsev Y, Gibbs KD, Merker JD, Zehnder JL, Davis RW, Nolan GP, Ji HP, et al. Abstract B6: Identification of novel mutations in the inhibitory adaptor protein LNK in patients with JAK2 V617F-negative and -positive chronic myeloproliferative neoplasms Clinical Cancer Research. 16. DOI: 10.1158/1078-0432.Tcmusa10-B6 |
0.525 |
|
| 2009 |
O'Gorman WE, Dooms H, Thorne SH, Kuswanto WF, Simonds EF, Krutzik PO, Nolan GP, Abbas AK. The initial phase of an immune response functions to activate regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 183: 332-9. PMID 19542444 DOI: 10.4049/Jimmunol.0900691 |
0.723 |
|
| 2008 |
Kotecha N, Flores NJ, Irish JM, Simonds EF, Sakai DS, Archambeault S, Diaz-Flores E, Coram M, Shannon KM, Nolan GP, Loh ML. Single-cell profiling identifies aberrant STAT5 activation in myeloid malignancies with specific clinical and biologic correlates. Cancer Cell. 14: 335-43. PMID 18835035 DOI: 10.1016/J.Ccr.2008.08.014 |
0.769 |
|
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