| Year |
Citation |
Score |
| 2024 |
Barnett D, Zimmer TS, Booraem C, Palaguachi F, Meadows SM, Xiao H, Chouchani ET, Orr AG, Orr AL. Mitochondrial complex III-derived ROS amplify immunometabolic changes in astrocytes and promote dementia pathology. Biorxiv : the Preprint Server For Biology. PMID 39229090 DOI: 10.1101/2024.08.19.608708 |
0.341 |
|
| 2024 |
Vargas-Castillo A, Sun Y, Smythers AL, Grauvogel L, Dumesic PA, Emont MP, Tsai LT, Rosen ED, Zammit NW, Shaffer SM, Ordonez M, Chouchani ET, Gygi SP, Wang T, Sharma AK, et al. Development of a functional beige fat cell line uncovers independent subclasses of cells expressing UCP1 and the futile creatine cycle. Cell Metabolism. PMID 39084217 DOI: 10.1016/j.cmet.2024.07.002 |
0.68 |
|
| 2024 |
Sprenger HG, Mittenbühler MJ, Sun Y, Van Vranken JG, Schindler S, Jayaraj A, Khetarpal SA, Vargas-Castillo A, Puszynska AM, Spinelli JB, Armani A, Kunchok T, Ryback B, Seo HS, Song K, ... ... Chouchani ET, et al. Ergothioneine boosts mitochondrial respiration and exercise performance via direct activation of MPST. Biorxiv : the Preprint Server For Biology. PMID 38645260 DOI: 10.1101/2024.04.10.588849 |
0.509 |
|
| 2024 |
Reddy A, Winther S, Tran N, Xiao H, Jakob J, Garrity R, Smith A, Ordonez M, Laznik-Bogoslavski D, Rothstein JD, Mills EL, Chouchani ET. Monocarboxylate transporters facilitate succinate uptake into brown adipocytes. Nature Metabolism. PMID 38378996 DOI: 10.1038/s42255-024-00981-5 |
0.341 |
|
| 2023 |
Reddy A, Winther S, Tran N, Xiao H, Jakob J, Garrity R, Smith A, Mills EL, Chouchani ET. Monocarboxylate transporters facilitate succinate uptake into brown adipocytes. Biorxiv : the Preprint Server For Biology. PMID 36909624 DOI: 10.1101/2023.03.01.530625 |
0.326 |
|
| 2023 |
Mittenbühler MJ, Jedrychowski MP, Van Vranken JG, Sprenger HG, Wilensky S, Dumesic PA, Sun Y, Tartaglia A, Bogoslavski D, A M, Xiao H, Blackmore KA, Reddy A, Gygi SP, Chouchani ET, et al. Isolation of extracellular fluids reveals novel secreted bioactive proteins from muscle and fat tissues. Cell Metabolism. PMID 36681077 DOI: 10.1016/j.cmet.2022.12.014 |
0.564 |
|
| 2022 |
Xiao H, Bozi LHM, Sun Y, Riley CL, Philip VM, Chen M, Li J, Zhang T, Mills EL, Emont MP, Sun W, Reddy A, Garrity R, Long J, Becher T, ... ... Chouchani ET, et al. Architecture of the outbred brown fat proteome defines regulators of metabolic physiology. Cell. PMID 36334589 DOI: 10.1016/j.cell.2022.10.003 |
0.773 |
|
| 2022 |
Bertholet AM, Natale AM, Bisignano P, Suzuki J, Fedorenko A, Hamilton J, Brustovetsky T, Kazak L, Garrity R, Chouchani ET, Brustovetsky N, Grabe M, Kirichok Y. Mitochondrial uncouplers induce proton leak by activating AAC and UCP1. Nature. 606: 180-187. PMID 35614225 DOI: 10.1038/s41586-022-04747-5 |
0.706 |
|
| 2022 |
Murphy MP, Chouchani ET. Why succinate? Physiological regulation by a mitochondrial coenzyme Q sentinel. Nature Chemical Biology. 18: 461-469. PMID 35484255 DOI: 10.1038/s41589-022-01004-8 |
0.332 |
|
| 2022 |
Rahbani JF, Chouchani ET, Spiegelman BM, Kazak L. Measurement of Futile Creatine Cycling Using Respirometry. Methods in Molecular Biology (Clifton, N.J.). 2448: 141-153. PMID 35167096 DOI: 10.1007/978-1-0716-2087-8_10 |
0.751 |
|
| 2021 |
Mills EL, Harmon C, Jedrychowski MP, Xiao H, Gruszczyk AV, Bradshaw GA, Tran N, Garrity R, Laznik-Bogoslavski D, Szpyt J, Prendeville H, Lynch L, Murphy MP, Gygi SP, Spiegelman BM, ... Chouchani ET, et al. Cysteine 253 of UCP1 regulates energy expenditure and sex-dependent adipose tissue inflammation. Cell Metabolism. PMID 34861155 DOI: 10.1016/j.cmet.2021.11.003 |
0.579 |
|
| 2021 |
Keinan O, Valentine JM, Xiao H, Mahata SK, Reilly SM, Abu-Odeh M, Deluca JH, Dadpey B, Cho L, Pan A, Yu RT, Dai Y, Liddle C, Downes M, Evans RM, ... ... Chouchani ET, et al. Glycogen metabolism links glucose homeostasis to thermogenesis in adipocytes. Nature. PMID 34707293 DOI: 10.1038/s41586-021-04019-8 |
0.344 |
|
| 2021 |
Sun Y, Rahbani JF, Jedrychowski MP, Riley CL, Vidoni S, Bogoslavski D, Hu B, Dumesic PA, Zeng X, Wang AB, Knudsen NH, Kim CR, Marasciullo A, Millán JL, Chouchani ET, et al. Mitochondrial TNAP controls thermogenesis by hydrolysis of phosphocreatine. Nature. PMID 33981039 DOI: 10.1038/s41586-021-03533-z |
0.801 |
|
| 2021 |
Yan S, Kumari M, Xiao H, Jacobs C, Kochumon S, Jedrychowski M, Chouchani E, Ahmad R, Rosen ED. IRF3 reduces adipose thermogenesis via ISG15-mediated reprogramming of glycolysis. The Journal of Clinical Investigation. PMID 33571167 DOI: 10.1172/JCI144888 |
0.669 |
|
| 2020 |
Lagarde D, Jeanson Y, Barreau C, Moro C, Peyriga L, Cahoreau E, Guissard C, Arnaud E, Galinier A, Bouzier-Sore AK, Pellerin L, Chouchani ET, Penicaud L, Ader I, Portais JC, et al. Lactate fluxes mediated by the monocarboxylate transporter-1 are key determinants of the metabolic activity of beige adipocytes. The Journal of Biological Chemistry. PMID 33268383 DOI: 10.1074/jbc.RA120.016303 |
0.377 |
|
| 2020 |
Madala HR, Helenius IT, Zhou W, Mills E, Zhang Y, Liu Y, Metelo AM, Kelley ML, Punganuru S, Kim KB, Olenchock B, Rhee E, Intlekofer AM, Lliopoulos O, Chouchani E, et al. Nitrogen trapping as a therapeutic strategy in tumors with mitochondrial dysfunction. Cancer Research. PMID 32651261 DOI: 10.1158/0008-5472.Can-20-0246 |
0.362 |
|
| 2020 |
Jedrychowski MP, Lu GZ, Szpyt J, Mariotti M, Garrity R, Paulo JA, Schweppe DK, Laznik-Bogoslavski D, Kazak L, Murphy MP, Gladyshev VN, Gygi SP, Chouchani ET, Spiegelman BM. Facultative protein selenation regulates redox sensitivity, adipose tissue thermogenesis, and obesity. Proceedings of the National Academy of Sciences of the United States of America. PMID 32358195 DOI: 10.1073/Pnas.2001387117 |
0.76 |
|
| 2020 |
Xiao H, Jedrychowski MP, Schweppe DK, Huttlin EL, Yu Q, Heppner DE, Li J, Long J, Mills EL, Szpyt J, He Z, Du G, Garrity R, Reddy A, Vaites LP, ... ... Chouchani ET, et al. A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging. Cell. PMID 32109415 DOI: 10.1016/J.Cell.2020.02.012 |
0.316 |
|
| 2020 |
Bertholet AM, Chouchani ET, Kazak L, Angelin A, Fedorenko A, Long JZ, Vidoni S, Garrity R, Cho J, Terada N, Wallace D, Spiegelman BM, Kirichok YV. Molecular Identity and Regulatory Mechanisms of the Mitochondrial Uncoupling Protein of Non-Adipose Tissues Biophysical Journal. 118: 185a. DOI: 10.1016/J.Bpj.2019.11.1127 |
0.8 |
|
| 2019 |
Chouchani ET, Kajimura S. Metabolic adaptation and maladaptation in adipose tissue. Nature Metabolism. 1: 189-200. PMID 31903450 DOI: 10.1038/s42255-018-0021-8 |
0.682 |
|
| 2019 |
Bertholet AM, Chouchani ET, Kazak L, Angelin A, Fedorenko A, Long JZ, Vidoni S, Garrity R, Cho J, Terada N, Wallace DC, Spiegelman BM, Kirichok Y. H transport is an integral function of the mitochondrial ADP/ATP carrier. Nature. 571: 515-520. PMID 31341297 DOI: 10.1038/S41586-019-1400-3 |
0.777 |
|
| 2019 |
Kazak L, Rahbani JF, Samborska B, Lu GZ, Jedrychowski MP, Lajoie M, Zhang S, Ramsay LC, Dou FY, Tenen D, Chouchani ET, Dzeja P, Watson IR, Tsai L, Rosen ED, et al. Ablation of adipocyte creatine transport impairs thermogenesis and causes diet-induced obesity. Nature Metabolism. 1: 360-370. PMID 31161155 DOI: 10.1038/s42255-019-0035-x |
0.765 |
|
| 2018 |
Chouchani ET, Kazak L, Spiegelman BM. New Advances in Adaptive Thermogenesis: UCP1 and Beyond. Cell Metabolism. PMID 30503034 DOI: 10.1016/J.Cmet.2018.11.002 |
0.75 |
|
| 2018 |
Mills EL, Pierce KA, Jedrychowski MP, Garrity R, Winther S, Vidoni S, Yoneshiro T, Spinelli JB, Lu GZ, Kazak L, Banks AS, Haigis MC, Kajimura S, Murphy MP, Gygi SP, ... ... Chouchani ET, et al. Accumulation of succinate controls activation of adipose tissue thermogenesis. Nature. PMID 30022159 DOI: 10.1038/S41586-018-0353-2 |
0.786 |
|
| 2018 |
Paulo JA, Jedrychowski MP, Chouchani ET, Kazak L, Gygi SP. Multiplexed isobaric tag-based profiling of seven murine tissues following in vivo nicotine treatment using a minimalistic proteomics strategy. Proteomics. e1700326. PMID 29660237 DOI: 10.1002/Pmic.201700326 |
0.653 |
|
| 2018 |
Chouchani E. A novel redox-activation pathway controls the anti-obesity function of brown adipose tissue Free Radical Biology and Medicine. 128. DOI: 10.1016/J.Freeradbiomed.2018.10.185 |
0.549 |
|
| 2018 |
Bertholet AM, Fedorenko A, Chouchani ET, Kazak L, Angelin A, Vidoni S, Cho J, Terada N, Spiegelman BM, Wallace DC, Kirichok Y. Molecular Identity and Regulatory Mechanisms of the Mitochondrial Uncoupling Protein of Regular Somatic Tissues Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 1859: e50. DOI: 10.1016/J.Bbabio.2018.09.150 |
0.753 |
|
| 2017 |
Kazak L, Chouchani ET, Lu GZ, Jedrychowski MP, Bare CJ, Mina AI, Kumari M, Zhang S, Vuckovic I, Laznik-Bogoslavski D, Dzeja P, Banks AS, Rosen ED, Spiegelman BM. Genetic Depletion of Adipocyte Creatine Metabolism Inhibits Diet-Induced Thermogenesis and Drives Obesity. Cell Metabolism. 26: 693. PMID 28978428 DOI: 10.1016/J.Cmet.2017.09.007 |
0.781 |
|
| 2017 |
Kazak L, Chouchani ET, Lu GZ, Jedrychowski MP, Bare CJ, Mina AI, Kumari M, Zhang S, Vuckovic I, Laznik-Bogoslavski D, Dzeja P, Banks AS, Rosen ED, Spiegelman BM. Genetic Depletion of Adipocyte Creatine Metabolism Inhibits Diet-Induced Thermogenesis and Drives Obesity. Cell Metabolism. PMID 28844881 DOI: 10.1016/J.Cmet.2017.08.009 |
0.802 |
|
| 2017 |
Chouchani ET, Kazak L, Spiegelman BM. Mitochondrial reactive oxygen species and adipose tissue thermogenesis: bridging physiology and mechanisms. The Journal of Biological Chemistry. PMID 28842500 DOI: 10.1074/Jbc.R117.789628 |
0.777 |
|
| 2017 |
Chouchani ET, James AM, Methner C, Pell VR, Prime TA, Erikson BK, Forkink M, Lau GY, Bright TP, Menger KE, Fearnley IM, Krieg T, Murphy MP. Identification and Quantification of Protein S-nitrosation by Nitrite in the Mouse Heart during Ischemia. The Journal of Biological Chemistry. PMID 28710281 DOI: 10.1074/jbc.M117.798744 |
0.328 |
|
| 2017 |
Kazak L, Chouchani ET, Stavrovskaya IG, Lu GZ, Jedrychowski MP, Egan DF, Kumari M, Kong X, Erickson BK, Szpyt J, Rosen ED, Murphy MP, Kristal BS, Gygi SP, Spiegelman BM. UCP1 deficiency causes brown fat respiratory chain depletion and sensitizes mitochondria to calcium overload-induced dysfunction. Proceedings of the National Academy of Sciences of the United States of America. PMID 28630339 DOI: 10.1073/Pnas.1705406114 |
0.794 |
|
| 2017 |
Ortega SP, Chouchani ET, Boudina S. Stress turns on the heat: Regulation of mitochondrial biogenesis and UCP1 by ROS in adipocytes. Adipocyte. 6: 56-61. PMID 28452586 DOI: 10.1080/21623945.2016.1273298 |
0.481 |
|
| 2017 |
Bertholet AM, Kazak L, Chouchani ET, Bogaczyńska MG, Paranjpe I, Wainwright GL, Bétourné A, Kajimura S, Spiegelman BM, Kirichok Y. Mitochondrial Patch Clamp of Beige Adipocytes Reveals UCP1-Positive and UCP1-Negative Cells Both Exhibiting Futile Creatine Cycling. Cell Metabolism. 25: 811-822.e4. PMID 28380374 DOI: 10.1016/J.Bbabio.2018.09.358 |
0.77 |
|
| 2016 |
Chouchani ET, Kazak L, Jedrychowski MP, Lu GZ, Erickson BK, Szpyt J, Pierce KA, Laznik-Bogoslavski D, Vetrivelan R, Clish CB, Robinson AJ, Gygi SP, Spiegelman BM. Corrigendum: Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1. Nature. PMID 27281219 DOI: 10.1038/Nature18279 |
0.691 |
|
| 2016 |
Chouchani ET, Kazak L, Jedrychowski MP, Lu GZ, Erickson BK, Szpyt J, Pierce KA, Laznik-Bogoslavski D, Vetrivelan R, Clish CB, Robinson AJ, Gygi SP, Spiegelman BM. Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1. Nature. PMID 27027295 DOI: 10.1038/Nature17399 |
0.795 |
|
| 2015 |
Kazak L, Chouchani ET, Jedrychowski MP, Erickson BK, Shinoda K, Cohen P, Vetrivelan R, Lu GZ, Laznik-Bogoslavski D, Hasenfuss SC, Kajimura S, Gygi SP, Spiegelman BM. A Creatine-Driven Substrate Cycle Enhances Energy Expenditure and Thermogenesis in Beige Fat. Cell. 163: 643-55. PMID 26496606 DOI: 10.1016/J.Cell.2015.09.035 |
0.822 |
|
| 2015 |
Cunniff B, Newick K, Nelson KJ, Wozniak AN, Beuschel S, Leavitt B, Bhave A, Butnor K, Koenig A, Chouchani ET, James AM, Haynes AC, Lowther WT, Murphy MP, Shukla A, et al. Disabling Mitochondrial Peroxide Metabolism via Combinatorial Targeting of Peroxiredoxin 3 as an Effective Therapeutic Approach for Malignant Mesothelioma. Plos One. 10: e0127310. PMID 26011724 DOI: 10.1371/Journal.Pone.0127310 |
0.336 |
|
| 2014 |
Chouchani ET, Pell VR, Gaude E, Aksentijević D, Sundier SY, Robb EL, Logan A, Nadtochiy SM, Ord EN, Smith AC, Eyassu F, Shirley R, Hu CH, Dare AJ, James AM, et al. Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS. Nature. 515: 431-5. PMID 25383517 DOI: 10.1038/Nature13909 |
0.358 |
|
| 2014 |
Chouchani E, Pell V, Gaude E, Aksentijevic D, Shattock M, Davidson S, Duchen M, Frezza C, Krieg T, Murphy M. P439Comparative metabolomics identifies conserved metabolic pathways that control mitochondrial ROS production during ischaemia reperfusion injury Cardiovascular Research. 103: S81.1-S81. DOI: 10.1093/Cvr/Cvu091.118 |
0.495 |
|
| 2012 |
Hurd TR, Collins Y, Abakumova I, Chouchani ET, Baranowski B, Fearnley IM, Prime TA, Murphy MP, James AM. Inactivation of pyruvate dehydrogenase kinase 2 by mitochondrial reactive oxygen species. The Journal of Biological Chemistry. 287: 35153-60. PMID 22910903 DOI: 10.1074/jbc.M112.400002 |
0.318 |
|
| 2010 |
Chouchani ET, Hurd TR, Nadtochiy SM, Brookes PS, Fearnley IM, Lilley KS, Smith RA, Murphy MP. Identification of S-nitrosated mitochondrial proteins by S-nitrosothiol difference in gel electrophoresis (SNO-DIGE): implications for the regulation of mitochondrial function by reversible S-nitrosation. The Biochemical Journal. 430: 49-59. PMID 20533907 DOI: 10.1042/Bj20100633 |
0.306 |
|
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