| Year |
Citation |
Score |
| 2023 |
Tan PK, Ostertag T, Rosenthal SB, Chilin-Fuentes D, Aidnik H, Linker S, Murphy K, Miner JN, Brenner DA. Role of Hepatic Stellate and Liver Sinusoidal Endothelial Cells in a Human Primary Cell Three-Dimensional Model of Nonalcoholic Steatohepatitis. The American Journal of Pathology. PMID 38158078 DOI: 10.1016/j.ajpath.2023.12.005 |
0.353 |
|
| 2023 |
Li N, Li X, Ding Y, Liu X, Diggle K, Kisseleva T, Brenner DA. SREBP Regulation of Lipid Metabolism in Liver Disease, and Therapeutic Strategies. Biomedicines. 11. PMID 38137501 DOI: 10.3390/biomedicines11123280 |
0.343 |
|
| 2023 |
Brenner DA. Alternatives to animal testing to assess NASH drugs and hepatotoxicity. Hepatology (Baltimore, Md.). PMID 37934631 DOI: 10.1097/HEP.0000000000000669 |
0.314 |
|
| 2023 |
Kim HY, Sakane S, Eguileor A, Weber RCG, Lee W, Liu X, Lam K, Ishizuka K, Rosenthal SB, Diggle K, Brenner DA, Kisseleva T. The origin and fate of liver myofibroblasts. Cellular and Molecular Gastroenterology and Hepatology. PMID 37743012 DOI: 10.1016/j.jcmgh.2023.09.008 |
0.396 |
|
| 2023 |
Liu X, Lam K, Zhao H, Sakane S, Kim HY, Eguileor A, Diggle K, Wu S, Gontijo Weber RC, Soroosh P, Hosseini M, Mekeel K, Brenner DA, Kisseleva T. Isolation of primary human liver cells from normal and nonalcoholic steatohepatitis livers. Star Protocols. 4: 102391. PMID 37405925 DOI: 10.1016/j.xpro.2023.102391 |
0.345 |
|
| 2023 |
Liu X, Brenner DA, Kisseleva T. Human Hepatic Stellate Cells: Isolation and Characterization. Methods in Molecular Biology (Clifton, N.J.). 2669: 221-232. PMID 37247063 DOI: 10.1007/978-1-0716-3207-9_13 |
0.351 |
|
| 2023 |
Zeng S, Rosati E, Saggau C, Messner B, Chu H, Duan Y, Hartmann P, Wang Y, Ma S, Huang WJM, Lee J, Lee SM, Carvalho-Gontijo R, Zhang V, Hoffmann JP, ... ... Brenner DA, et al. Candida albicans-specific Th17 cell-mediated response contributes to alcohol-associated liver disease. Cell Host & Microbe. 31: 389-404.e7. PMID 36893735 DOI: 10.1016/j.chom.2023.02.001 |
0.595 |
|
| 2022 |
Nishio T, Koyama Y, Fuji H, Ishizuka K, Iwaisako K, Taura K, Hatano E, Brenner DA, Kisseleva T. The Role of Mesothelin in Activation of Portal Fibroblasts in Cholestatic Liver Injury. Biology. 11. PMID 36358290 DOI: 10.3390/biology11111589 |
0.329 |
|
| 2022 |
Carvalho-Gontijo R, Han C, Zhang L, Zhang V, Hosseini M, Mekeel K, Schnabl B, Loomba R, Karin M, Brenner DA, Kisseleva T. Metabolic Injury of Hepatocytes Promotes Progression of NAFLD and AALD. Seminars in Liver Disease. 42: 233-249. PMID 36001995 DOI: 10.1055/s-0042-1755316 |
0.616 |
|
| 2021 |
Fuji H, Miller G, Nishio T, Koyama Y, Lam K, Zhang V, Loomba R, Brenner D, Kisseleva T. The role of Mesothelin signaling in Portal Fibroblasts in the pathogenesis of cholestatic liver fibrosis. Frontiers in Molecular Biosciences. 8: 790032. PMID 34966784 DOI: 10.3389/fmolb.2021.790032 |
0.387 |
|
| 2021 |
Duan Y, Chu H, Brandl K, Jiang L, Zeng S, Meshgin N, Papachristoforou E, Argemi J, Mendes BG, Wang Y, Su H, Sun W, Llorente C, Hendrikx T, Liu X, ... ... Brenner DA, et al. CRIg on liver macrophages clears pathobionts and protects against alcoholic liver disease. Nature Communications. 12: 7172. PMID 34887405 DOI: 10.1038/s41467-021-27385-3 |
0.609 |
|
| 2021 |
Nishio T, Koyama Y, Liu X, Rosenthal SB, Yamamoto G, Fuji H, Baglieri J, Li N, Brenner LN, Iwaisako K, Taura K, Hagood JS, LaRusso NF, Bera TK, Pastan I, ... Brenner DA, et al. Immunotherapy-based targeting of MSLN activated portal fibroblasts is a strategy for treatment of cholestatic liver fibrosis. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34253615 DOI: 10.1073/pnas.2101270118 |
0.324 |
|
| 2021 |
Baglieri J, Zhang C, Liang S, Liu X, Nishio T, Rosenthal SB, Dhar D, Su H, Cong M, Jia J, Hosseini M, Karin M, Kisseleva T, Brenner DA. Non-degradable collagen increases liver fibrosis but not hepatocellular carcinoma in mice. The American Journal of Pathology. PMID 34119473 DOI: 10.1016/j.ajpath.2021.05.019 |
0.309 |
|
| 2021 |
Ganguly S, Muench GA, Shang L, Rosenthal SB, Rahman G, Wang R, Wang Y, Kwon HC, Diomino AM, Kisseleva T, Soorosh P, Hosseini M, Knight R, Schnabl B, Brenner DA, et al. Non-alcoholic Steatohepatitis and HCC in a Hyperphagic Mouse Accelerated by Western Diet. Cellular and Molecular Gastroenterology and Hepatology. PMID 34062281 DOI: 10.1016/j.jcmgh.2021.05.010 |
0.55 |
|
| 2021 |
Zhou R, Llorente C, Cao J, Zaramela LS, Zeng S, Gao B, Li SZ, Welch RD, Huang FQ, Qi LW, Pan C, Huang Y, Zhou P, Beussen I, Zhang Y, ... ... Brenner DA, et al. Intestinal α1-2-fucosylation contributes to obesity and steatohepatitis in mice. Cellular and Molecular Gastroenterology and Hepatology. PMID 33631374 DOI: 10.1016/j.jcmgh.2021.02.009 |
0.472 |
|
| 2021 |
Rosenthal SB, Liu X, Ganguly S, Dhar D, Pasillas MP, Ricciardelli E, Li RZ, Troutman TD, Kisseleva T, Glass CK, Brenner DA. Heterogeneity of hepatic stellate cells in a mouse model of non-alcoholic steatohepatitis (NASH). Hepatology (Baltimore, Md.). PMID 33550587 DOI: 10.1002/hep.31743 |
0.303 |
|
| 2021 |
Gratte FD, Pasic S, Abu Bakar NDB, Gogoi-Tiwari J, Liu X, Carlessi R, Kisseleva T, Brenner DA, Ramm GA, Olynyk JK, Tirnitz-Parker JEE. Previous liver regeneration induces fibro-protective mechanisms during thioacetamide-induced chronic liver injury. The International Journal of Biochemistry & Cell Biology. 105933. PMID 33540107 DOI: 10.1016/j.biocel.2021.105933 |
0.38 |
|
| 2020 |
Jiang C, Iwaisako K, Cong M, Diggle K, Hassanein T, Brenner DA, Kisseleva T. Traditional Chinese Medicine Fuzheng Huayu Prevents Development of Liver Fibrosis in Mice. Archives of Clinical and Biomedical Research. 4: 561-580. PMID 33210080 DOI: 10.26502/acbr.50170125 |
0.309 |
|
| 2020 |
Kisseleva T, Brenner D. Molecular and cellular mechanisms of liver fibrosis and its regression. Nature Reviews. Gastroenterology & Hepatology. 18: 151-166. PMID 33128017 DOI: 10.1038/s41575-020-00372-7 |
0.406 |
|
| 2020 |
Jiang L, Lang S, Duan Y, Zhang X, Gao B, Chopyk J, Schwanemann LK, Ventura-Cots M, Bataller R, Bosques-Padilla F, Verna EC, Abraldes JG, Brown RS, Vargas V, Altamirano J, ... ... Brenner DA, et al. Intestinal virome in patients with alcoholic hepatitis. Hepatology (Baltimore, Md.). PMID 32654263 DOI: 10.1002/Hep.31459 |
0.584 |
|
| 2020 |
Oh TG, Kim SM, Caussy C, Fu T, Guo J, Bassirian S, Singh S, Madamba EV, Bettencourt R, Richards L, Raffatellu M, Dorrestein PC, Yu RT, Atkins AR, Huan T, ... Brenner DA, et al. A Universal Gut-Microbiome-Derived Signature Predicts Cirrhosis. Cell Metabolism. PMID 32610095 DOI: 10.1016/J.Cmet.2020.06.005 |
0.407 |
|
| 2020 |
Riopel M, Moon JS, Bandyopadhyay GK, You S, Lam K, Liu X, Kisseleva T, Brenner D, Lee YS. Inhibition of Prolyl Hydroxylases Increases Hepatic Insulin And Decreases Glucagon Sensitivity by An HIF-2α-Dependent Mechanism. Molecular Metabolism. 101039. PMID 32534258 DOI: 10.1016/J.Molmet.2020.101039 |
0.325 |
|
| 2020 |
Baeza-Raja B, Goodyear A, Liu X, Lam K, Yamamoto L, Li Y, Dodson GS, Takeuchi T, Kisseleva T, Brenner DA, Dabbagh K. Pharmacological inhibition of P2RX7 ameliorates liver injury by reducing inflammation and fibrosis. Plos One. 15: e0234038. PMID 32492075 DOI: 10.1371/Journal.Pone.0234038 |
0.458 |
|
| 2020 |
Gao B, Emami A, Zhou R, Lang S, Duan Y, Wang Y, Jiang L, Loomba R, Brenner DA, Stärkel P, Schnabl B. Functional Microbial Responses to Alcohol Abstinence in Patients With Alcohol Use Disorder. Frontiers in Physiology. 11: 370. PMID 32390870 DOI: 10.3389/Fphys.2020.00370 |
0.531 |
|
| 2020 |
Zhang M, Haughey M, Wang NY, Blease K, Kapoun AM, Couto S, Belka I, Hoey T, Groza M, Hartke J, Bennett B, Cain J, Gurney A, Benish B, Castiglioni P, ... ... Brenner DA, et al. Targeting the Wnt signaling pathway through R-spondin 3 identifies an anti-fibrosis treatment strategy for multiple organs. Plos One. 15: e0229445. PMID 32160239 DOI: 10.1371/Journal.Pone.0229445 |
0.338 |
|
| 2020 |
Xu J, Ma HY, Liu X, Rosenthal S, Baglieri J, McCubbin R, Sun M, Koyama Y, Geoffroy CG, Saijo K, Shang L, Nishio T, Maricic I, Kreifeldt M, Kusumanchi P, ... ... Brenner DA, et al. Blockade of IL-17 signaling reverses alcohol-induced liver injury and excessive alcohol drinking in mice. Jci Insight. 5. PMID 32051339 DOI: 10.1172/Jci.Insight.131277 |
0.338 |
|
| 2020 |
Liu X, Xu J, Rosenthal S, Zhang LJ, McCubbin R, Meshgin N, Shang L, Koyama Y, Ma HY, Sharma S, Heinz S, Glass CK, Benner C, Brenner DA, Kisseleva T. Identification of Lineage-specific Transcription Factors That Prevent Activation of Hepatic Stellate Cells and Promote Fibrosis Resolution. Gastroenterology. PMID 31982409 DOI: 10.1053/J.Gastro.2020.01.027 |
0.487 |
|
| 2020 |
Dhar D, Baglieri J, Kisseleva T, Brenner DA. Mechanisms of liver fibrosis and its role in liver cancer. Experimental Biology and Medicine (Maywood, N.J.). 1535370219898141. PMID 31924111 DOI: 10.1177/1535370219898141 |
0.457 |
|
| 2020 |
Loomba R, Oh TG, Kim S, Singh S, Bettencourt R, Yu RT, Brenner DA, Sirlin CB, Downes M, Evans RM. Su1594 GUT MICROBIOME METAGENOMICS REVEALS FUNGAL MYCOBIOME ALTERATION IN NAFLD CIRRHOSIS WITH VALIDATION IN A GEOGRAPHICALLY INDEPENDENT COHORT Gastroenterology. 158. DOI: 10.1016/S0016-5085(20)34047-6 |
0.366 |
|
| 2020 |
Lam KP, Rosenthal SB, Meshgin N, Arreola R, Baglieri J, Nishio T, Diggle K, Brenner DA, Kisseleva T, Liu X. 452 Comparative Analysis Of Gene Expression Profile In Primary Human Normal, Nafld, And Nash Hepatic Stellate Cells Identifies Novel Targets For Anti-Fibrotic Therapy. Gastroenterology. 158. DOI: 10.1016/S0016-5085(20)33853-1 |
0.366 |
|
| 2019 |
Ma HY, Yamamoto G, Xu J, Liu X, Karin D, Kim JY, Alexandrov LB, Koyama Y, Nishio T, Benner C, Heinz S, Rosenthal SB, Liang S, Sun M, Karin G, ... ... Brenner DA, et al. IL-17 signaling in steatotic hepatocytes and macrophages promotes hepatocellular carcinoma in alcohol-related liver disease. Journal of Hepatology. PMID 31899206 DOI: 10.1016/J.Jhep.2019.12.016 |
0.342 |
|
| 2019 |
Sun X, Seidman JS, Zhao P, Troutman TD, Spann NJ, Que X, Zhou F, Liao Z, Pasillas M, Yang X, Magida JA, Kisseleva T, Brenner DA, Downes M, Evans RM, et al. Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis. Cell Metabolism. PMID 31761566 DOI: 10.1016/J.Cmet.2019.10.014 |
0.348 |
|
| 2019 |
Kisseleva T, Brenner DA. The Crosstalk between Hepatocytes, Hepatic Macrophages, and Hepatic Stellate Cells Facilitates Alcoholic Liver Disease. Cell Metabolism. 30: 850-852. PMID 31693880 DOI: 10.1016/J.Cmet.2019.10.010 |
0.402 |
|
| 2019 |
Loomba R, Seguritan V, Li W, Long T, Klitgord N, Bhatt A, Dulai PS, Caussy C, Bettencourt R, Highlander SK, Jones MB, Sirlin CB, Schnabl B, Brinkac L, Schork N, ... ... Brenner DA, et al. Gut Microbiome-Based Metagenomic Signature for Non-invasive Detection of Advanced Fibrosis in Human Nonalcoholic Fatty Liver Disease. Cell Metabolism. 30: 607. PMID 31484056 DOI: 10.1016/j.cmet.2019.08.002 |
0.564 |
|
| 2019 |
Wang L, Mazagova M, Pan C, Yang S, Brandl K, Liu J, Reilly SM, Wang Y, Miao Z, Loomba R, Lu N, Guo Q, Liu J, Yu RT, Downes M, ... ... Brenner DA, et al. YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity. Proceedings of the National Academy of Sciences of the United States of America. PMID 31289229 DOI: 10.1073/Pnas.1904360116 |
0.57 |
|
| 2019 |
Nishio T, Hu R, Koyama Y, Liang S, Rosenthal SB, Yamamoto G, Karin D, Baglieri J, Ma HY, Xu J, Liu X, Dhar D, Iwaisako K, Taura K, Brenner DA, et al. Activated Hepatic Stellate Cells and Portal Fibroblasts contribute to cholestatic liver fibrosis in MDR2 knockout mice. Journal of Hepatology. PMID 31071368 DOI: 10.1016/J.Jhep.2019.04.012 |
0.493 |
|
| 2019 |
Baglieri J, Brenner DA, Kisseleva T. The Role of Fibrosis and Liver-Associated Fibroblasts in the Pathogenesis of Hepatocellular Carcinoma. International Journal of Molecular Sciences. 20. PMID 30959975 DOI: 10.3390/Ijms20071723 |
0.42 |
|
| 2019 |
Caussy C, Tripathi A, Humphrey G, Bassirian S, Singh S, Faulkner C, Bettencourt R, Rizo E, Richards L, Xu ZZ, Downes MR, Evans RM, Brenner DA, Sirlin CB, Knight R, et al. A gut microbiome signature for cirrhosis due to nonalcoholic fatty liver disease. Nature Communications. 10: 1406. PMID 30926798 DOI: 10.1038/S41467-019-09455-9 |
0.418 |
|
| 2019 |
Caussy C, Bhargava M, Villesen IF, Gudmann NS, Leeming DJ, Karsdal MA, Faulkner C, Bao D, Liu A, Lo MT, Bettencourt R, Bassirian S, Richards L, Brenner DA, Chen CH, et al. Collagen formation assessed by PRO-C3 is an heritable trait and is associated with liver fibrosis assessed by MRE. Hepatology (Baltimore, Md.). PMID 30859582 DOI: 10.1002/Hep.30610 |
0.394 |
|
| 2019 |
Chen L, Brenner DA, Kisseleva T. Combatting Fibrosis: Exosome-Based Therapies in the Regression of Liver Fibrosis. Hepatology Communications. 3: 180-192. PMID 30766956 DOI: 10.1002/hep4.1290 |
0.374 |
|
| 2019 |
Caussy C, Tripathi A, Humphrey G, Bassirian S, Singh S, Faulkner C, Bettencourt R, Rizo E, Richards L, Xu Z, Downes M, Evans RE, Brenner DA, Sirlin CB, Knight R, et al. PS-157-Gut microbiome signature for cirrhosis due to non-alcoholoic fatty liver disease: A prospective twin and family study Journal of Hepatology. 70: e98-e99. DOI: 10.1016/S0618-8278(19)30175-6 |
0.405 |
|
| 2019 |
Lui X, Rosenthal SB, Meshgin N, Wu R, Diggle K, Dorko K, Presnell S, Tsukamoto H, Brenner DA, Kisseleva T. 465 – Comparative Analysis of Gene Expression in Primary Human Normal and Alcohol-Injured Hepatic Stellate Cells Identifies Novel Targets for Anti-Fibrotic Therapy Authors Gastroenterology. 156. DOI: 10.1016/S0016-5085(19)39974-3 |
0.354 |
|
| 2018 |
Caussy C, Ajmera VH, Puri P, Hsu CL, Bassirian S, Mgdsyan M, Singh S, Faulkner C, Valasek MA, Rizo E, Richards L, Brenner DA, Sirlin CB, Sanyal AJ, Loomba R. Serum metabolites detect the presence of advanced fibrosis in derivation and validation cohorts of patients with non-alcoholic fatty liver disease. Gut. PMID 30567742 DOI: 10.1136/Gutjnl-2018-317584 |
0.404 |
|
| 2018 |
Caussy C, Hsu C, Singh S, Bassirian S, Kolar J, Faulkner C, Sinha N, Bettencourt R, Gara N, Valasek MA, Schnabl B, Richards L, Brenner DA, Hofmann AF, Loomba R. Serum bile acid patterns are associated with the presence of NAFLD in twins, and dose-dependent changes with increase in fibrosis stage in patients with biopsy-proven NAFLD. Alimentary Pharmacology & Therapeutics. PMID 30506692 DOI: 10.1111/Apt.15035 |
0.605 |
|
| 2018 |
Liang S, Ma HY, Zhong Z, Dhar D, Liu X, Xu J, Koyama Y, Nishio T, Karin D, Karin G, Mccubbin R, Zhang C, Hu R, Yang G, Chen L, ... ... Brenner DA, et al. NADPH Oxidase 1 in Liver Macrophages Promotes Inflammation and Tumor Development in Mice. Gastroenterology. PMID 30445007 DOI: 10.1053/J.Gastro.2018.11.019 |
0.395 |
|
| 2018 |
Allaband C, McDonald D, Vázquez-Baeza Y, Minich JJ, Tripathi A, Brenner DA, Loomba R, Smarr L, Sandborn WJ, Schnabl B, Dorrestein P, Zarrinpar A, Knight R. Microbiome 101: Studying, Analyzing, and Interpreting Gut Microbiome Data for Clinicians. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. PMID 30240894 DOI: 10.1016/J.Cgh.2018.09.017 |
0.501 |
|
| 2018 |
Tripathi A, Debelius J, Brenner DA, Karin M, Loomba R, Schnabl B, Knight R. Publisher Correction: The gut-liver axis and the intersection with the microbiome. Nature Reviews. Gastroenterology & Hepatology. PMID 29785003 DOI: 10.1038/S41575-018-0031-8 |
0.629 |
|
| 2018 |
Tripathi A, Debelius J, Brenner DA, Karin M, Loomba R, Schnabl B, Knight R. The gut-liver axis and the intersection with the microbiome. Nature Reviews. Gastroenterology & Hepatology. PMID 29748586 DOI: 10.1038/S41575-018-0011-Z |
0.641 |
|
| 2018 |
Lan T, Li C, Yang G, Sun Y, Zhuang L, Ou Y, Li H, Wang G, Kisseleva T, Brenner D, Guo J. Sphingosine kinase 1 promotes liver fibrosis by preventing miR-19b-3p-mediated inhibition of CCR2. Hepatology (Baltimore, Md.). PMID 29572892 DOI: 10.1002/Hep.29885 |
0.511 |
|
| 2018 |
Caussy C, Hsu C, Lo MT, Liu A, Bettencourt R, Ajmera VH, Bassirian S, Hooker J, Sy E, Richards L, Schork N, Schnabl B, Brenner DA, Sirlin CB, Chen CH, et al. Novel link between gut-microbiome derived metabolite and shared gene-effects with hepatic steatosis and fibrosis in NAFLD. Hepatology (Baltimore, Md.). PMID 29572891 DOI: 10.1002/Hep.29892 |
0.617 |
|
| 2018 |
Caussy C, Hsu C, Singh S, Bassirian S, Kolar J, Faulkner C, Bettencourt R, Valasek MA, Richards LM, Brenner DA, Loomba R. Su1507 - Serum Bile Acids Alteration is Associated with the Presence of NAFLD in Twins, and Dose-Dependent Changes with Increase in Fibrosis Stage in Patients with Biopsy-Proven NAFLD Gastroenterology. 154. DOI: 10.1016/S0016-5085(18)33848-4 |
0.319 |
|
| 2018 |
Nishio T, Hu R, Koyama Y, Xu J, Liu X, Ma H, Liang S, Brenner DA, Kisseleva T. 891 - Activation of Portal Fibroblasts in Cholestatic Fibrosis Gastroenterology. 154: S-1108. DOI: 10.1016/S0016-5085(18)33686-2 |
0.371 |
|
| 2017 |
Xu J, Ma HY, Liang S, Sun M, Karin G, Koyama Y, Hu R, Quehenberger O, Davidson NO, Dennis EA, Kisseleva T, Brenner DA. The role of human cytochrome P450 2E1 in liver inflammation and fibrosis. Hepatology Communications. 1: 1043-1057. PMID 29404441 DOI: 10.1002/hep4.1115 |
0.383 |
|
| 2017 |
Drinane MC, Yaqoob U, Yu H, Luo F, Greuter T, Arab JP, Kostallari E, Verma VK, Maiers J, De Assuncao TM, Simons M, Mukhopadhyay D, Kisseleva T, Brenner DA, Urrutia R, et al. Synectin promotes fibrogenesis by regulating PDGFR isoforms through distinct mechanisms. Jci Insight. 2. PMID 29263300 DOI: 10.1172/Jci.Insight.92821 |
0.451 |
|
| 2017 |
Llorente C, Jepsen P, Inamine T, Wang L, Bluemel S, Wang HJ, Loomba R, Bajaj JS, Schubert ML, Sikaroodi M, Gillevet PM, Xu J, Kisseleva T, Ho SB, DePew J, ... ... Brenner DA, et al. Publisher Correction: Gastric acid suppression promotes alcoholic liver disease by inducing overgrowth of intestinal Enterococcus. Nature Communications. 8: 2137. PMID 29233961 DOI: 10.1038/S41467-017-01779-8 |
0.557 |
|
| 2017 |
Hartmann P, Hochrath K, Horvath A, Chen P, Seebauer CT, Llorente C, Wang L, Alnouti Y, Fouts DE, Stärkel P, Loomba R, Coulter S, Liddle C, Yu RT, Ling L, ... ... Brenner DA, et al. Modulation of the intestinal bile acid-FXR-FGF15 axis improves alcoholic liver disease in mice. Hepatology (Baltimore, Md.). PMID 29159825 DOI: 10.1002/Hep.29676 |
0.622 |
|
| 2017 |
Caussy C, Chen J, Alquiraish MH, Cepin S, Nguyen P, Hernandez C, Yin M, Bettencourt R, Cachay ER, Jayakumar S, Fortney L, Hooker J, Sy E, Valasek MA, Rizo E, ... ... Brenner D, et al. Association Between Obesity and Discordance in Fibrosis Stage Determination by Magnetic Resonance vs Transient Elastography in Patients with Non-alcoholic Liver Disease. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. PMID 29104128 DOI: 10.1016/J.Cgh.2017.10.037 |
0.382 |
|
| 2017 |
Shang L, Hosseini M, Liu X, Kisseleva T, Brenner DA. Human hepatic stellate cell isolation and characterization. Journal of Gastroenterology. PMID 29094206 DOI: 10.1007/S00535-017-1404-4 |
0.42 |
|
| 2017 |
Llorente C, Jepsen P, Inamine T, Wang L, Bluemel S, Wang HJ, Loomba R, Bajaj JS, Schubert ML, Sikaroodi M, Gillevet PM, Xu J, Kisseleva T, Ho SB, DePew J, ... ... Brenner DA, et al. Gastric acid suppression promotes alcoholic liver disease by inducing overgrowth of intestinal Enterococcus. Nature Communications. 8: 837. PMID 29038503 DOI: 10.1038/S41467-017-00796-X |
0.633 |
|
| 2017 |
Caussy C, Soni M, Cui J, Bettencourt R, Schork N, Chen CH, Ikhwan MA, Bassirian S, Cepin S, Gonzalez MP, Mendler M, Kono Y, Vodkin I, Mekeel K, Haldorson J, ... ... Brenner DA, et al. Nonalcoholic fatty liver disease with cirrhosis increases familial risk for advanced fibrosis. The Journal of Clinical Investigation. PMID 28628033 DOI: 10.1172/Jci93465 |
0.418 |
|
| 2017 |
Cong M, Zhao W, Liu T, Wang P, Fan X, Zhai Q, Bao X, Zhang D, You H, Kisseleva T, Brenner DA, Jia J, Zhuang H. Protective effect of human serum amyloid P on CCl4-induced acute liver injury in mice. International Journal of Molecular Medicine. PMID 28627620 DOI: 10.3892/Ijmm.2017.3028 |
0.471 |
|
| 2017 |
Vollmann EH, Cao L, Amatucci A, Reynolds T, Hamann S, Dalkilic-Liddle I, Cameron TO, Hossbach M, Kauffman KJ, Mir FF, Anderson DG, Novobrantseva T, Koteliansky V, Kisseleva T, Brenner D, et al. Identification of Novel Fibrosis Modifiers by In Vivo siRNA Silencing. Molecular Therapy. Nucleic Acids. 7: 314-323. PMID 28624207 DOI: 10.1016/J.Omtn.2017.04.014 |
0.417 |
|
| 2017 |
Loomba R, Seguritan V, Li W, Long T, Klitgord N, Bhatt A, Dulai PS, Caussy C, Bettencourt R, Highlander SK, Jones MB, Sirlin CB, Schnabl B, Brinkac L, Schork N, ... ... Brenner DA, et al. Gut Microbiome-Based Metagenomic Signature for Non-invasive Detection of Advanced Fibrosis in Human Nonalcoholic Fatty Liver Disease. Cell Metabolism. 25: 1054-1062.e5. PMID 28467925 DOI: 10.1016/J.Cmet.2017.04.001 |
0.614 |
|
| 2017 |
Koyama Y, Wang P, Liang S, Iwaisako K, Liu X, Xu J, Zhang M, Sun M, Cong M, Karin D, Taura K, Benner C, Heinz S, Bera T, Brenner DA, et al. Mesothelin/mucin 16 signaling in activated portal fibroblasts regulates cholestatic liver fibrosis. The Journal of Clinical Investigation. PMID 28287406 DOI: 10.1172/Jci88845 |
0.475 |
|
| 2017 |
Koyama Y, Brenner DA. Liver inflammation and fibrosis. The Journal of Clinical Investigation. 127: 55-64. PMID 28045404 DOI: 10.1172/Jci88881 |
0.476 |
|
| 2017 |
Park CC, Nguyen P, Hernandez C, Bettencourt R, Ramirez KS, Fortney LE, Hooker J, Sy E, Alquiraish MH, Valasek MA, Rizo E, Richards L, Brenner D, Sirlin CB, Loomba R. Magnetic resonance elastography vs. transient elastography in detection of fibrosis and noninvasive measurement of steatosis in patients with biopsy-proven nonalcoholic fatty liver disease Journal of Hepatology. 66. DOI: 10.1016/S0168-8278(17)30769-9 |
0.385 |
|
| 2017 |
Koyama Y, Hu R, Xu J, Liu X, Ma H, Liang S, Brenner DA, Kisseleva T. The Characteristics of Myofibroblasts in Various Cholestatic Liver Injury Models in Mice Gastroenterology. 152: S1104. DOI: 10.1016/S0016-5085(17)33719-8 |
0.388 |
|
| 2017 |
Xu J, Liang S, Ma H, Sun M, Koyama Y, Kisseleva T, Brenner DA. The Role of Human CYP2E1 in Liver Fibrosis Gastroenterology. 152: S1072-S1073. DOI: 10.1016/S0016-5085(17)33620-X |
0.448 |
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| 2016 |
Park CC, Nguyen P, Hernandez C, Bettencourt R, Ramirez K, Fortney L, Hooker J, Sy E, Alquiraish MH, Valasek MA, Rizo E, Richards L, Brenner D, Sirlin CB, Loomba R. Magnetic Resonance Elastography vs Transient Elastography in Detection of Fibrosis and Noninvasive Measurement of Steatosis in Patients with Biopsy-proven Nonalcoholic Fatty Liver Disease. Gastroenterology. PMID 27911262 DOI: 10.1053/J.Gastro.2016.10.026 |
0.344 |
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| 2016 |
Patel NS, Hooker J, Gonzalez M, Bhatt A, Nguyen P, Ramirez K, Richards L, Rizo E, Hernandez C, Kisseleva T, Schnabl B, Brenner D, Sirlin CB, Loomba R. Weight loss decreases magnetic resonance elastography estimated liver stiffness in nonalcoholic fatty liver disease. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. PMID 27712981 DOI: 10.1016/J.Cgh.2016.09.150 |
0.589 |
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| 2016 |
Decaris ML, Li KW, Emson CL, Gatmaitan M, Liu S, Wang Y, Nyangau E, Colangelo M, Angel TE, Beysen C, Cui J, Hernandez C, Lazaro L, Brenner DA, Turner SM, et al. Identifying NAFLD Patients with Active Fibrosis by Measuring Extracellular Matrix Remodeling Rates in Tissue and Blood. Hepatology (Baltimore, Md.). PMID 27706836 DOI: 10.1002/Hep.28860 |
0.464 |
|
| 2016 |
Karin D, Koyama Y, Brenner D, Kisseleva T. The characteristics of activated portal fibroblasts/myofibroblasts in liver fibrosis. Differentiation. 92: 84-92. PMID 27591095 DOI: 10.1016/J.Diff.2016.07.001 |
0.499 |
|
| 2016 |
Koyama Y, Xu J, Liu X, Brenner DA. New Developments on the Treatment of Liver Fibrosis. Digestive Diseases (Basel, Switzerland). 34: 589-596. PMID 27332862 DOI: 10.1159/000445269 |
0.49 |
|
| 2016 |
Cui J, Chen CH, Lo MT, Schork N, Bettencourt R, Gonzalez MP, Bhatt A, Hooker J, Shaffer K, Nelson KE, Long MT, Brenner DA, Sirlin CB, Loomba R. Shared genetic effects between hepatic steatosis and fibrosis: A prospective twin study. Hepatology (Baltimore, Md.). PMID 27315352 DOI: 10.1016/S0168-8278(16)00824-2 |
0.443 |
|
| 2016 |
Kim RG, Nguyen P, Bettencourt R, Dulai PS, Haufe W, Hooker J, Minocha J, Valasek MA, Aryafar H, Brenner DA, Sirlin CB, Loomba R. Magnetic resonance elastography identifies fibrosis in adults with alpha-1 antitrypsin deficiency liver disease: a prospective study. Alimentary Pharmacology & Therapeutics. PMID 27279429 DOI: 10.1111/Apt.13691 |
0.377 |
|
| 2016 |
Ma HY, Xu J, Liu X, Zhu Y, Gao B, Karin M, Tsukamoto H, Jeste DV, Grant I, Roberts AJ, Contet C, Geoffroy C, Zheng B, Brenner D, Kisseleva T. The role of IL-17 signaling in regulation of the liver-brain axis and intestinal permeability in Alcoholic Liver Disease. Current Pathobiology Reports. 4: 27-35. PMID 27239399 DOI: 10.1007/S40139-016-0097-3 |
0.412 |
|
| 2016 |
Cui J, Philo L, Nguyen P, Hofflich H, Hernandez C, Bettencourt R, Richards L, Salotti J, Bhatt A, Hooker J, Haufe W, Hooker C, Brenner DA, Sirlin CB, Loomba R. Sitagliptin versus placebo in the treatment of nonalcoholic fatty liver disease: A randomized controlled trial. Journal of Hepatology. PMID 27151177 DOI: 10.1016/j.jhep.2016.04.021 |
0.43 |
|
| 2016 |
Wang P, Koyama Y, Liu X, Xu J, Ma HY, Liang S, Kim IH, Brenner DA, Kisseleva T. Promising Therapy Candidates for Liver Fibrosis. Frontiers in Physiology. 7: 47. PMID 26909046 DOI: 10.3389/Fphys.2016.00047 |
0.481 |
|
| 2016 |
Schnabl B, Farshchi-Heydari S, Loomba R, Mattrey RF, Hoh CK, Sirlin CB, Brenner DA, Behling CA, Vera DR. Staging of fibrosis in experimental non-alcoholic steatohepatitis by quantitative molecular imaging in rat models. Nuclear Medicine and Biology. 43: 179-87. PMID 26872443 DOI: 10.1016/J.Nucmedbio.2015.11.009 |
0.561 |
|
| 2016 |
Liang S, Kisseleva T, Brenner DA. The Role of NADPH Oxidases (NOXs) in Liver Fibrosis and the Activation of Myofibroblasts. Frontiers in Physiology. 7: 17. PMID 26869935 DOI: 10.3389/Fphys.2016.00017 |
0.505 |
|
| 2016 |
Wang L, Fouts DE, Stärkel P, Hartmann P, Chen P, Llorente C, DePew J, Moncera K, Ho SB, Brenner DA, Hooper LV, Schnabl B. Intestinal REG3 Lectins Protect against Alcoholic Steatohepatitis by Reducing Mucosa-Associated Microbiota and Preventing Bacterial Translocation. Cell Host & Microbe. 19: 227-39. PMID 26867181 DOI: 10.1016/J.Chom.2016.01.003 |
0.603 |
|
| 2016 |
Liu X, Brenner DA. Liver: DNA methylation controls liver fibrogenesis. Nature Reviews. Gastroenterology & Hepatology. PMID 26860269 DOI: 10.1038/Nrgastro.2016.16 |
0.427 |
|
| 2016 |
Kim RG, Nguyen P, Bettencourt R, Dulai PS, Haufe W, Hooker J, Minocha J, Valasek MA, Aryafar H, Brenner DA, Sirlin CB, Loomba R. Tu1706 Magnetic Resonance Elastography Identifies Fibrosis in Adults With Alpha-1 Antitrypsin Deficiency Liver Disease: A Pilot Prospective Study Gastroenterology. 150. DOI: 10.1016/S0016-5085(16)33947-6 |
0.358 |
|
| 2016 |
Koyama Y, Wang P, Liang S, Sun M, Brenner DA, Kisseleva T. Tu1697 Mesothelin Signaling Regulates Proliferation of Portal Fibroblasts and Contributes to the Pathogenesis of Cholestatic Liver Fibrosis in Mice Gastroenterology. 150: S1165-S1166. DOI: 10.1016/S0016-5085(16)33938-5 |
0.445 |
|
| 2016 |
Patel NS, Hooker J, Gonzalez M, Bhatt A, Nguyen P, Ramirez K, Richards L, Rizo E, Hernandez C, Kisseleva T, Schnabl B, Brenner DA, Sirlin CB, Loomba R. Mo1542 Effect of Weight Loss on MRE Estimated Stiffness in Patients With Nonalcoholic Fatty Liver Disease Gastroenterology. 150. DOI: 10.1016/S0016-5085(16)33846-X |
0.577 |
|
| 2016 |
Cui JY, Chen C, Lo M, Schork N, Bettencourt R, Bhatt A, Hooker J, Nelson KE, Long MT, Brenner DA, Sirlin CB, Loomba R. 947 Shared Genetic Effects Between Hepatic Steatosis and Fibrosis: A Prospective Twin Study Gastroenterology. 150. DOI: 10.1016/S0016-5085(16)33560-0 |
0.361 |
|
| 2016 |
Liu X, Benner C, Heinz S, Brenner DA, Kisseleva T. 226 The Mechanism of Hepatic Stellate Cell Inactivation During Reversal of Liver Fibrosis Gastroenterology. 150. DOI: 10.1016/S0016-5085(16)33456-4 |
0.477 |
|
| 2016 |
Schnabl B, Farshchi-Heydari S, Loomba R, Mattrey RF, Hoh CK, Sirlin CB, Brenner DA, Behling CA, Vera DR. Staging of fibrosis in experimental non-alcoholic steatohepatitis by quantitative molecular imaging in rat models Nuclear Medicine and Biology. 43: 179-187. DOI: 10.1016/j.nucmedbio.2015.11.009 |
0.47 |
|
| 2015 |
Brenner DA, Paik YH, Schnabl B. Role of Gut Microbiota in Liver Disease. Journal of Clinical Gastroenterology. 49: S25-7. PMID 26447960 DOI: 10.1097/Mcg.0000000000000391 |
0.644 |
|
| 2015 |
Loomba R, Schork N, Chen CH, Bettencourt R, Bhatt A, Ang B, Nguyen P, Hernandez C, Richards L, Salotti J, Lin S, Seki E, Nelson KE, Sirlin CB, Brenner D, et al. Heritability of Hepatic Fibrosis and Steatosis Based on a Prospective Twin Study. Gastroenterology. PMID 26299412 DOI: 10.1053/J.Gastro.2015.08.011 |
0.435 |
|
| 2015 |
Lan T, Kisseleva T, Brenner DA. Deficiency of NOX1 or NOX4 Prevents Liver Inflammation and Fibrosis in Mice through Inhibition of Hepatic Stellate Cell Activation. Plos One. 10: e0129743. PMID 26222337 DOI: 10.1371/Journal.Pone.0129743 |
0.506 |
|
| 2015 |
Koyama Y, Brenner DA. New therapies for hepatic fibrosis. Clinics and Research in Hepatology and Gastroenterology. 39: S75-9. PMID 26206573 DOI: 10.1016/J.Clinre.2015.06.011 |
0.488 |
|
| 2015 |
Verna EC, Patel J, Bettencourt R, Nguyen P, Hernandez C, Valasek MA, Kisselva T, Brenner DA, Loomba R. Novel association between serum pentraxin-2 levels and advanced fibrosis in well-characterised patients with non-alcoholic fatty liver disease. Alimentary Pharmacology & Therapeutics. PMID 26119353 DOI: 10.1111/Apt.13292 |
0.4 |
|
| 2015 |
Seki E, Brenner DA. Recent advancement of molecular mechanisms of liver fibrosis. Journal of Hepato-Biliary-Pancreatic Sciences. 22: 512-8. PMID 25869468 DOI: 10.1002/Jhbp.245 |
0.504 |
|
| 2015 |
Kim IH, Kisseleva T, Brenner DA. Aging and liver disease. Current Opinion in Gastroenterology. 31: 184-91. PMID 25850346 DOI: 10.1097/Mog.0000000000000176 |
0.377 |
|
| 2015 |
Xu J, Cong M, Park TJ, Scholten D, Brenner DA, Kisseleva T. Contribution of bone marrow-derived fibrocytes to liver fibrosis. Hepatobiliary Surgery and Nutrition. 4: 34-47. PMID 25713803 DOI: 10.3978/J.Issn.2304-3881.2015.01.01 |
0.385 |
|
| 2015 |
Fang S, Suh JM, Reilly SM, Yu E, Osborn O, Lackey D, Yoshihara E, Perino A, Jacinto S, Lukasheva Y, Atkins AR, Khvat A, Schnabl B, Yu RT, Brenner DA, et al. Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance. Nature Medicine. 21: 159-65. PMID 25559344 DOI: 10.1038/Nm.3760 |
0.565 |
|
| 2015 |
Loomba R, Sirlin CB, Ang B, Bettencourt R, Jain R, Salotti J, Soaft L, Hooker J, Kono Y, Bhatt A, Hernandez L, Nguyen P, Noureddin M, Haufe W, Hooker C, ... ... Brenner DA, et al. Ezetimibe for the treatment of nonalcoholic steatohepatitis: assessment by novel magnetic resonance imaging and magnetic resonance elastography in a randomized trial (MOZART trial). Hepatology (Baltimore, Md.). 61: 1239-50. PMID 25482832 DOI: 10.1002/Hep.27647 |
0.358 |
|
| 2015 |
Mazagova M, Wang L, Anfora AT, Wissmueller M, Lesley SA, Miyamoto Y, Eckmann L, Dhungana S, Pathmasiri W, Sumner S, Westwater C, Brenner DA, Schnabl B. Commensal microbiota is hepatoprotective and prevents liver fibrosis in mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 1043-55. PMID 25466902 DOI: 10.1096/Fj.14-259515 |
0.661 |
|
| 2015 |
Xu J, Liu X, Brenner DA, Kisseleva T. Novel perspectives on the origins of the hepatic myofibroblasts Cell Health and Cytoskeleton. 7: 111-119. DOI: 10.2147/CHC.S57679 |
0.402 |
|
| 2015 |
Loomba R, Schork N, Chen C, Bhatt A, Ang B, Nguyen P, Hernandez C, Richards L, Salotti J, Lin S, Nelson K, Sirlin C, Brenner D. O040 : Heritability of hepatic fibrosis and hepatic steatosis, and their shared gene effects with metabolic traits in NAFLD: A prospective twin study Journal of Hepatology. 62: S209. DOI: 10.1016/S0168-8278(15)30048-9 |
0.385 |
|
| 2015 |
Loomba R, Schork N, Chen C, Bhatt A, Ang B, Nguyen P, Hernandez C, Richards L, Salotti J, Lin SC, Nelson KE, Sirlin C, Brenner DA. 277 Heritability of Hepatic Fibrosis and Hepatic Steatosis, and Their Shared Gene Effects With Metabolic Traits in NAFLD: A Prospective Twin Study Gastroenterology. 148: S-974-S-975. DOI: 10.1016/S0016-5085(15)33329-1 |
0.407 |
|
| 2015 |
Koyama Y, Brenner DA. New therapies for hepatic fibrosis Clinics and Research in Hepatology and Gastroenterology. 39: S75-S79. DOI: 10.1016/j.clinre.2015.06.011 |
0.387 |
|
| 2015 |
Koyama Y, Wang P, Brenner DA, Kisseleva T. Chapter 6 - Stellate Cells, Portal Myofibroblasts, and Epithelial-to-Mesenchymal Transition Stellate Cells in Health and Disease. 87-106. DOI: 10.1016/B978-0-12-800134-9.00006-3 |
0.366 |
|
| 2015 |
Seki E, Brenner DA. Recent advancement of molecular mechanisms of liver fibrosis Journal of Hepato-Biliary-Pancreatic Sciences. 22: 512-518. DOI: 10.1002/jhbp.245 |
0.405 |
|
| 2014 |
Xu J, Liu X, Gao B, Karin M, Tsukamoto H, Brenner D, Kisseleva T. New Approaches for Studying Alcoholic Liver Disease. Current Pathobiology Reports. 2: 171-183. PMID 26594598 DOI: 10.1007/S40139-014-0053-Z |
0.469 |
|
| 2014 |
Loomba R, Wolfson T, Ang B, Hooker J, Behling C, Peterson M, Valasek M, Lin G, Brenner D, Gamst A, Ehman R, Sirlin C. Magnetic resonance elastography predicts advanced fibrosis in patients with nonalcoholic fatty liver disease: a prospective study. Hepatology (Baltimore, Md.). 60: 1920-8. PMID 25103310 DOI: 10.1002/Hep.27362 |
0.435 |
|
| 2014 |
Iwaisako K, Jiang C, Zhang M, Cong M, Moore-Morris TJ, Park TJ, Liu X, Xu J, Wang P, Paik YH, Meng F, Asagiri M, Murray LA, Hofmann AF, Iida T, ... ... Brenner DA, et al. Origin of myofibroblasts in the fibrotic liver in mice. Proceedings of the National Academy of Sciences of the United States of America. 111: E3297-305. PMID 25074909 DOI: 10.1073/Pnas.1400062111 |
0.49 |
|
| 2014 |
Lopez-Sanchez I, Dunkel Y, Roh YS, Mittal Y, De Minicis S, Muranyi A, Singh S, Shanmugam K, Aroonsakool N, Murray F, Ho SB, Seki E, Brenner DA, Ghosh P. GIV/Girdin is a central hub for profibrogenic signalling networks during liver fibrosis. Nature Communications. 5: 4451. PMID 25043713 DOI: 10.1038/Ncomms5451 |
0.471 |
|
| 2014 |
Inokuchi-Shimizu S, Park EJ, Roh YS, Yang L, Zhang B, Song J, Liang S, Pimienta M, Taniguchi K, Wu X, Asahina K, Lagakos W, Mackey MR, Akira S, Ellisman MH, ... ... Brenner DA, et al. TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis. The Journal of Clinical Investigation. 124: 3566-78. PMID 24983318 DOI: 10.1172/Jci74068 |
0.435 |
|
| 2014 |
Liu C, Chen X, Yang L, Kisseleva T, Brenner DA, Seki E. Transcriptional repression of the transforming growth factor β (TGF-β) pseudoreceptor BMP and activin membrane-bound inhibitor (BAMBI) by nuclear factor κB (NF-κB) p50 enhances TGF-β signaling in hepatic stellate cells Journal of Biological Chemistry. 289: 7082-7091. PMID 24448807 DOI: 10.1074/Jbc.M113.543769 |
0.371 |
|
| 2014 |
Schnabl B, Brenner DA. Interactions between the intestinal microbiome and liver diseases Gastroenterology. 146: 1513-1524. PMID 24440671 DOI: 10.1053/J.Gastro.2014.01.020 |
0.63 |
|
| 2014 |
Paik YH, Kim J, Aoyama T, De Minicis S, Bataller R, Brenner DA. Role of NADPH oxidases in liver fibrosis. Antioxidants & Redox Signaling. 20: 2854-72. PMID 24040957 DOI: 10.1089/Ars.2013.5619 |
0.44 |
|
| 2014 |
Lemberger UJ, Penz-Österreicher M, Brenner D, Trauner M, Österreicher CH. P167 Lack Of Fsp1/S100A4 Attenuates Liver Fibrosis In Mice Journal of Hepatology. 60. DOI: 10.1016/S0168-8278(14)60329-9 |
0.421 |
|
| 2014 |
Chen P, Torralba M, Zengler K, Mutlu E, Keshavarzian A, Tsukamoto H, Nelson KE, Brenner DA, Fouts DE, Schnabl B. 387 Restoration of Intestinal Metabolic Homeostasis Results in Eubiosis and Protects Mice From Alcoholic Liver Disease Gastroenterology. 146: S-911. DOI: 10.1016/S0016-5085(14)63315-1 |
0.618 |
|
| 2013 |
Brenner DA. Reversibility of liver fibrosis. Gastroenterology & Hepatology. 9: 737-9. PMID 24764791 |
0.364 |
|
| 2013 |
Liu X, Xu J, Brenner DA, Kisseleva T. Reversibility of Liver Fibrosis and Inactivation of Fibrogenic Myofibroblasts. Current Pathobiology Reports. 1: 209-214. PMID 24000319 DOI: 10.1007/S40139-013-0018-7 |
0.459 |
|
| 2013 |
Loomba R, Doycheva I, Bettencourt R, Cohen B, Wassel CL, Brenner D, Barrett-Connor E. Serum γ-glutamyltranspeptidase predicts all-cause, cardiovascular and liver mortality in older adults. Journal of Clinical and Experimental Hepatology. 3: 4-11. PMID 23997501 DOI: 10.1016/J.Jceh.2012.10.004 |
0.304 |
|
| 2013 |
De Minicis S, Rychlicki C, Agostinelli L, Saccomanno S, Trozzi L, Candelaresi C, Bataller R, Millán C, Brenner DA, Vivarelli M, Mocchegiani F, Marzioni M, Benedetti A, Svegliati-Baroni G. Semaphorin 7A contributes to TGF-β-mediated liver fibrogenesis. The American Journal of Pathology. 183: 820-30. PMID 23850082 DOI: 10.1016/J.Ajpath.2013.05.030 |
0.493 |
|
| 2013 |
Noureddin M, Lam J, Peterson MR, Middleton M, Hamilton G, Le TA, Bettencourt R, Changchien C, Brenner DA, Sirlin C, Loomba R. Utility of magnetic resonance imaging versus histology for quantifying changes in liver fat in nonalcoholic fatty liver disease trials. Hepatology (Baltimore, Md.). 58: 1930-40. PMID 23696515 DOI: 10.1002/Hep.26455 |
0.375 |
|
| 2013 |
Conigliaro A, Amicone L, Costa V, De Santis Puzzonia M, Mancone C, Sacchetti B, Cicchini C, Garibaldi F, Brenner DA, Kisseleva T, Bianco P, Tripodi M. Evidence for a common progenitor of epithelial and mesenchymal components of the liver. Cell Death and Differentiation. 20: 1116-23. PMID 23686136 DOI: 10.1038/Cdd.2013.49 |
0.43 |
|
| 2013 |
Meurer SK, Alsamman M, Sahin H, Wasmuth HE, Kisseleva T, Brenner DA, Trautwein C, Weiskirchen R, Scholten D. Overexpression of endoglin modulates TGF-β1-signalling pathways in a novel immortalized mouse hepatic stellate cell line. Plos One. 8: e56116. PMID 23437087 DOI: 10.1371/Journal.Pone.0056116 |
0.402 |
|
| 2013 |
Patel NS, Peterson MR, Brenner DA, Heba E, Sirlin C, Loomba R. Association between novel MRI-estimated pancreatic fat and liver histology-determined steatosis and fibrosis in non-alcoholic fatty liver disease. Alimentary Pharmacology & Therapeutics. 37: 630-9. PMID 23383649 DOI: 10.1111/Apt.12237 |
0.429 |
|
| 2013 |
Loomba R, Yang HI, Su J, Brenner D, Barrett-Connor E, Iloeje U, Chen CJ. Synergism between obesity and alcohol in increasing the risk of hepatocellular carcinoma: a prospective cohort study. American Journal of Epidemiology. 177: 333-42. PMID 23355498 DOI: 10.1093/Aje/Kws252 |
0.315 |
|
| 2013 |
Kisseleva T, Brenner DA. Inactivation of myofibroblasts during regression of liver fibrosis. Cell Cycle (Georgetown, Tex.). 12: 381-2. PMID 23324345 DOI: 10.4161/Cc.23549 |
0.526 |
|
| 2013 |
De Minicis S, Kisseleva T, Francis H, Baroni GS, Benedetti A, Brenner D, Alvaro D, Alpini G, Marzioni M. Liver carcinogenesis: rodent models of hepatocarcinoma and cholangiocarcinoma. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association For the Study of the Liver. 45: 450-9. PMID 23177172 DOI: 10.1016/J.Dld.2012.10.008 |
0.359 |
|
| 2013 |
Miura K, Yang L, van Rooijen N, Brenner DA, Ohnishi H, Seki E. Toll-like receptor 2 and palmitic acid cooperatively contribute to the development of nonalcoholic steatohepatitis through inflammasome activation in mice. Hepatology (Baltimore, Md.). 57: 577-89. PMID 22987396 DOI: 10.1002/Hep.26081 |
0.357 |
|
| 2013 |
Schnabl B, Brenner DA. Fibroblast growth factor inducible 14 as potential target in patients with alcoholic hepatitis. Gut. 62: 335-6. PMID 22717452 DOI: 10.1136/Gutjnl-2012-302644 |
0.589 |
|
| 2013 |
Alsamman M, Weiskirchen R, Wasmuth H, Brenner D, Trautwein C, Scholten D. 136 ENDOGLIN DEFICIENCY IN HEPATIC STELLATE CELLS HAS A DIFFERENTIAL EFFECT ON LIVER FIBROSIS AND TGF-b SIGNALLING IN TWO EXPERIMENTAL MODELS OF MURINE LIVER FIBROSIS Journal of Hepatology. 58. DOI: 10.1016/S0168-8278(13)60138-5 |
0.469 |
|
| 2013 |
Loomba R, Lam J, Wolfson T, Ang B, Bhatt A, Peterson MR, Brenner DA, Sirlin C. Mo1009 Magnetic Resonance Elastography Accurately Predicts Advanced Fibrosis in NAFLD: A Pilot Study With Paired-Liver Biopsy Gastroenterology. 144: S-1012. DOI: 10.1016/S0016-5085(13)63756-7 |
0.348 |
|
| 2013 |
Doycheva I, Noureddin M, Patel NS, Peterson MR, Brenner DA, Sirlin C, Loomba R. Mo1005 Effect of Weight Loss on Novel MRI Quantitative Changes in Liver and Pancreatic Fat in Patients With Biopsy-Proven Nonalcoholic Fatty Liver Disease Gastroenterology. 144. DOI: 10.1016/S0016-5085(13)63752-X |
0.419 |
|
| 2013 |
Inokuchi S, Yang L, Zhang B, Roh YS, Pimienta M, Song J, Brenner DA, Seki E. 456 TAK1-Mediated Signaling Regulates AMPK and Autophagy Pathways That Prevent Hepatic Steatosis and Hepatocarcinogenesis in Mice Gastroenterology. 144. DOI: 10.1016/S0016-5085(13)63524-6 |
0.367 |
|
| 2013 |
Park TJ, Cong M, Jiang C, Kramer M, Lupher ML, Brenner DA, Kisseleva T. 297 Deletion of Fibrocytes in Mice Attenuates Experimental Liver Fibrosis Gastroenterology. 144. DOI: 10.1016/S0016-5085(13)63499-X |
0.432 |
|
| 2013 |
Park TJ, Liu X, Zhang M, Kisseleva T, Brenner DA. 208 Deletion of PPARy in Hepatic Stellate Cells Attenuates Regression of Liver Fibrosis Gastroenterology. 144. DOI: 10.1016/S0016-5085(13)63489-7 |
0.395 |
|
| 2012 |
Brenner DA, Kisseleva T, Scholten D, Paik YH, Iwaisako K, Inokuchi S, Schnabl B, Seki E, De Minicis S, Oesterreicher C, Taura K. Origin of myofibroblasts in liver fibrosis. Fibrogenesis & Tissue Repair. 5: S17. PMID 23259769 DOI: 10.1186/1755-1536-5-S1-S17 |
0.663 |
|
| 2012 |
Hartmann P, Haimerl M, Mazagova M, Brenner DA, Schnabl B. Toll-like receptor 2-mediated intestinal injury and enteric tumor necrosis factor receptor I contribute to liver fibrosis in mice. Gastroenterology. 143: 1330-40.e1. PMID 22841787 DOI: 10.1053/J.Gastro.2012.07.099 |
0.637 |
|
| 2012 |
Aoyama T, Paik YH, Watanabe S, Laleu B, Gaggini F, Fioraso-Cartier L, Molango S, Heitz F, Merlot C, Szyndralewiez C, Page P, Brenner DA. Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent. Hepatology (Baltimore, Md.). 56: 2316-27. PMID 22806357 DOI: 10.1002/Hep.25938 |
0.457 |
|
| 2012 |
Seki E, Brenner DA, Karin M. A liver full of JNK: signaling in regulation of cell function and disease pathogenesis, and clinical approaches. Gastroenterology. 143: 307-20. PMID 22705006 DOI: 10.1053/J.Gastro.2012.06.004 |
0.431 |
|
| 2012 |
Meng F, Wang K, Aoyama T, Grivennikov SI, Paik Y, Scholten D, Cong M, Iwaisako K, Liu X, Zhang M, Osterreicher CH, Stickel F, Ley K, Brenner DA, Kisseleva T. Interleukin-17 signaling in inflammatory, Kupffer cells, and hepatic stellate cells exacerbates liver fibrosis in mice. Gastroenterology. 143: 765-76.e1-3. PMID 22687286 DOI: 10.1053/J.Gastro.2012.05.049 |
0.408 |
|
| 2012 |
Kisseleva T, Cong M, Paik Y, Scholten D, Jiang C, Benner C, Iwaisako K, Moore-Morris T, Scott B, Tsukamoto H, Evans SM, Dillmann W, Glass CK, Brenner DA. Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis. Proceedings of the National Academy of Sciences of the United States of America. 109: 9448-53. PMID 22566629 DOI: 10.1073/Pnas.1201840109 |
0.5 |
|
| 2012 |
Permutt Z, Le TA, Peterson MR, Seki E, Brenner DA, Sirlin C, Loomba R. Correlation between liver histology and novel magnetic resonance imaging in adult patients with non-alcoholic fatty liver disease - MRI accurately quantifies hepatic steatosis in NAFLD. Alimentary Pharmacology & Therapeutics. 36: 22-9. PMID 22554256 DOI: 10.1111/J.1365-2036.2012.05121.X |
0.422 |
|
| 2012 |
Iwaisako K, Haimerl M, Paik YH, Taura K, Kodama Y, Sirlin C, Yu E, Yu RT, Downes M, Evans RM, Brenner DA, Schnabl B. Protection from liver fibrosis by a peroxisome proliferator-activated receptor δ agonist. Proceedings of the National Academy of Sciences of the United States of America. 109: E1369-76. PMID 22538808 DOI: 10.1073/Pnas.1202464109 |
0.651 |
|
| 2012 |
Lee JK, Bettencourt R, Brenner D, Le TA, Barrett-Connor E, Loomba R. Association between serum interleukin-6 concentrations and mortality in older adults: the Rancho Bernardo study. Plos One. 7: e34218. PMID 22514624 DOI: 10.1371/Journal.Pone.0034218 |
0.379 |
|
| 2012 |
Le TA, Chen J, Changchien C, Peterson MR, Kono Y, Patton H, Cohen BL, Brenner D, Sirlin C, Loomba R. Effect of colesevelam on liver fat quantified by magnetic resonance in nonalcoholic steatohepatitis: a randomized controlled trial. Hepatology (Baltimore, Md.). 56: 922-32. PMID 22431131 DOI: 10.1002/Hep.25731 |
0.415 |
|
| 2012 |
Fouts DE, Torralba M, Nelson KE, Brenner DA, Schnabl B. Bacterial translocation and changes in the intestinal microbiome in mouse models of liver disease. Journal of Hepatology. 56: 1283-92. PMID 22326468 DOI: 10.1016/J.Jhep.2012.01.019 |
0.617 |
|
| 2012 |
Iwaisako K, Brenner DA, Kisseleva T. What's new in liver fibrosis? The origin of myofibroblasts in liver fibrosis. Journal of Gastroenterology and Hepatology. 27: 65-8. PMID 22320919 DOI: 10.1111/J.1440-1746.2011.07002.X |
0.481 |
|
| 2012 |
Kisseleva T, Brenner DA. The phenotypic fate and functional role for bone marrow-derived stem cells in liver fibrosis. Journal of Hepatology. 56: 965-72. PMID 22173163 DOI: 10.1016/J.Jhep.2011.09.021 |
0.48 |
|
| 2012 |
Permutt Z, Le TAT, Peterson MR, Seki E, Brenner DA, Sirlin C, Loomba R. Tu1028 Correlation Between Liver Histology and Novel Magnetic Resonance Imaging in Adult Patients With Nonalcoholic Fatty Liver Disease Gastroenterology. 142. DOI: 10.1016/S0016-5085(12)63927-4 |
0.397 |
|
| 2012 |
Le TAT, Chen J, Changchien C, Peterson MR, Cohen BL, Kono Y, Patton H, Brenner DA, Sirlin C, Loomba R. Tu1027 Effect of Colesevelam on Magnetic Resonance Imaging Derived Fat Maps in Nonalcoholic Steatohepatitis: A Randomized Controlled Trial Gastroenterology. 142. DOI: 10.1016/S0016-5085(12)63926-2 |
0.348 |
|
| 2012 |
Yang L, Inokuchi S, Park EJ, Song J, Pimienta M, Duarte P, Zhang B, Brenner DA, Seki E. 383 Ablation of TGFbeta Receptor II Inhibits Liver Injury, Inflammation, Fibrosis and Carcinogenesis in Hepatocyte Specific TAK1 Deleted Mice Gastroenterology. 142. DOI: 10.1016/S0016-5085(12)63545-8 |
0.364 |
|
| 2011 |
Paik YH, Brenner DA. NADPH oxidase mediated oxidative stress in hepatic fibrogenesis. The Korean Journal of Hepatology. 17: 251-7. PMID 22310788 DOI: 10.3350/Kjhep.2011.17.4.251 |
0.382 |
|
| 2011 |
Brenner DA, Seki E, Taura K, Kisseleva T, Deminicis S, Iwaisako K, Inokuchi S, Schnabl B, Oesterreicher CH, Paik YH, Miura K, Kodama Y. Non-alcoholic steatohepatitis-induced fibrosis: Toll-like receptors, reactive oxygen species and Jun N-terminal kinase. Hepatology Research : the Official Journal of the Japan Society of Hepatology. 41: 683-6. PMID 21711427 DOI: 10.1111/J.1872-034X.2011.00814.X |
0.581 |
|
| 2011 |
Scholten D, Reichart D, Paik YH, Lindert J, Bhattacharya J, Glass CK, Brenner DA, Kisseleva T. Migration of fibrocytes in fibrogenic liver injury. The American Journal of Pathology. 179: 189-98. PMID 21703401 DOI: 10.1016/J.Ajpath.2011.03.049 |
0.435 |
|
| 2011 |
DeLeve LD, Jaeschke H, Kalra VK, Asahina K, Brenner DA, Tsukamoto H. 15th International Symposium on Cells of the Hepatic Sinusoid, 2010. Liver International : Official Journal of the International Association For the Study of the Liver. 31: 762-72. PMID 21645207 DOI: 10.1111/J.1478-3231.2011.02527.X |
0.321 |
|
| 2011 |
Kisseleva T, von Köckritz-Blickwede M, Reichart D, McGillvray SM, Wingender G, Kronenberg M, Glass CK, Nizet V, Brenner DA. Fibrocyte-like cells recruited to the spleen support innate and adaptive immune responses to acute injury or infection. Journal of Molecular Medicine (Berlin, Germany). 89: 997-1013. PMID 21499735 DOI: 10.1007/S00109-011-0756-0 |
0.306 |
|
| 2011 |
Kisseleva T, Brenner DA. Anti-fibrogenic strategies and the regression of fibrosis. Best Practice & Research. Clinical Gastroenterology. 25: 305-17. PMID 21497747 DOI: 10.1016/J.Bpg.2011.02.011 |
0.482 |
|
| 2011 |
Inokuchi S, Tsukamoto H, Park E, Liu ZX, Brenner DA, Seki E. Toll-like receptor 4 mediates alcohol-induced steatohepatitis through bone marrow-derived and endogenous liver cells in mice. Alcoholism, Clinical and Experimental Research. 35: 1509-18. PMID 21463341 DOI: 10.1111/J.1530-0277.2011.01487.X |
0.445 |
|
| 2011 |
Paik YH, Iwaisako K, Seki E, Inokuchi S, Schnabl B, Österreicher CH, Kisseleva T, Brenner DA. The nicotinamide adenine dinucleotide phosphate oxidase (NOX) homologues NOX1 and NOX2/gp91phox mediate hepatic fibrosis in mice Hepatology. 53: 1730-1741. PMID 21384410 DOI: 10.1002/Hep.24281 |
0.657 |
|
| 2011 |
Yan AW, Fouts DE, Brandl J, Stärkel P, Torralba M, Schott E, Tsukamoto H, Nelson KE, Brenner DA, Schnabl B. Enteric dysbiosis associated with a mouse model of alcoholic liver disease. Hepatology (Baltimore, Md.). 53: 96-105. PMID 21254165 DOI: 10.1002/Hep.24018 |
0.579 |
|
| 2011 |
Gao B, Seki E, Brenner DA, Friedman S, Cohen JI, Nagy L, Szabo G, Zakhari S. Innate immunity in alcoholic liver disease. American Journal of Physiology. Gastrointestinal and Liver Physiology. 300: G516-25. PMID 21252049 DOI: 10.1152/Ajpgi.00537.2010 |
0.411 |
|
| 2011 |
Parsons CJ, Stefanovic B, Seki E, Aoyama T, Latour AM, Marzluff WF, Rippe RA, Brenner DA. Mutation of the 5′-untranslated region stem-loop structure inhibits α1(I) collagen expression in vivo Journal of Biological Chemistry. 286: 8609-8619. PMID 21193410 DOI: 10.1074/Jbc.M110.189118 |
0.356 |
|
| 2011 |
Österreicher CH, Penz-Österreicher M, Grivennikov SI, Guma M, Koltsova EK, Datz C, Sasik R, Hardiman G, Karin M, Brenner DA. Fibroblast-specific protein 1 identifies an inflammatory subpopulation of macrophages in the liver. Proceedings of the National Academy of Sciences of the United States of America. 108: 308-13. PMID 21173249 DOI: 10.1073/Pnas.1017547108 |
0.482 |
|
| 2011 |
Osawa Y, Seki E, Kodama Y, Suetsugu A, Miura K, Adachi M, Ito H, Shiratori Y, Banno Y, Olefsky JM, Nagaki M, Moriwaki H, Brenner DA, Seishima M. Acid sphingomyelinase regulates glucose and lipid metabolism in hepatocytes through AKT activation and AMP-activated protein kinase suppression. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 1133-44. PMID 21163859 DOI: 10.1096/Fj.10-168351 |
0.342 |
|
| 2011 |
Brenner DA, Seki E, Taura K, Kisseleva T, Deminicis S, Iwaisako K, Inokuchi S, Schnabl B, Oesterreicher CH, Paik YH, Miura K, Kodama Y. Non-alcoholic steatohepatitis-induced fibrosis: Toll-like receptors, reactive oxygen species and Jun N-terminal kinase Hepatology Research. 41: 683-686. DOI: 10.1111/j.1872-034X.2011.00814.x |
0.531 |
|
| 2011 |
Penz-Oesterreicher M, Oesterreicher C, Iwaisako K, Brenner DA. 1053 Adiponectin Deficiency Attenuates Liver Fibrosis In Mice Journal of Hepatology. 54. DOI: 10.1016/S0168-8278(11)61055-6 |
0.431 |
|
| 2011 |
Oesterreicher C, Schramek D, Penz-Österreicher M, Kuba K, Penninger J, Brenner D. 1050 THE APELIN/APJ SYSTEM LINKS ANGIOGENESIS TO LIVER FIBROSIS Journal of Hepatology. 54: S417. DOI: 10.1016/S0168-8278(11)61052-0 |
0.461 |
|
| 2011 |
Iwaisako K, Jiang C, Scholten D, Paik Y, Meng F, Brenner DA, Kisseleva T. The Origin of Myofibroblasts Contributing to Liver Fibrosis in Mice Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)63802-X |
0.442 |
|
| 2011 |
Kisseleva T, Paik Y, Scholten D, Meng F, Iwaisako K, Jiang C, Brenner DA. Hepatic Stellate Cells Revert to an Inactive Phenotype During Regression of Fibrosis Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)63801-8 |
0.425 |
|
| 2010 |
Conigliaro A, Brenner DA, Kisseleva T. Hepatic progenitors for liver disease: current position. Stem Cells and Cloning : Advances and Applications. 3: 39-47. PMID 24198509 DOI: 10.2147/sccaa.s6035 |
0.349 |
|
| 2010 |
Miura K, Seki E, Ohnishi H, Brenner DA. Role of toll-like receptors and their downstream molecules in the development of nonalcoholic Fatty liver disease. Gastroenterology Research and Practice. 2010: 362847. PMID 21274430 DOI: 10.1155/2010/362847 |
0.407 |
|
| 2010 |
Zhang EE, Liu Y, Dentin R, Pongsawakul PY, Liu AC, Hirota T, Nusinow DA, Sun X, Landais S, Kodama Y, Brenner DA, Montminy M, Kay SA. Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis. Nature Medicine. 16: 1152-6. PMID 20852621 DOI: 10.1038/Nm.2214 |
0.367 |
|
| 2010 |
De Minicis S, Seki E, Paik YH, Osterreicher CH, Kodama Y, Kluwe J, Torozzi L, Miyai K, Benedetti A, Schwabe RF, Brenner DA. Role and cellular source of nicotinamide adenine dinucleotide phosphate oxidase in hepatic fibrosis Hepatology (Baltimore, Md.). 52: 1420-1430. PMID 20690191 DOI: 10.1002/Hep.23804 |
0.464 |
|
| 2010 |
Aoyama T, Inokuchi S, Brenner DA, Seki E. CX3CL1-CX3CR1 interaction prevents carbon tetrachloride-induced liver inflammation and fibrosis in mice. Hepatology (Baltimore, Md.). 52: 1390-400. PMID 20683935 DOI: 10.1002/Hep.23795 |
0.462 |
|
| 2010 |
Scholten D, Osterreicher CH, Scholten A, Iwaisako K, Gu G, Brenner DA, Kisseleva T. Genetic labeling does not detect epithelial-to-mesenchymal transition of cholangiocytes in liver fibrosis in mice. Gastroenterology. 139: 987-98. PMID 20546735 DOI: 10.1053/J.Gastro.2010.05.005 |
0.429 |
|
| 2010 |
Kisseleva T, Gigante E, Brenner DA. Recent advances in liver stem cell therapy. Current Opinion in Gastroenterology. 26: 395-402. PMID 20495456 DOI: 10.1097/Mog.0B013E32833A6Bec |
0.433 |
|
| 2010 |
Miura K, Kodama Y, Inokuchi S, Schnabl B, Aoyama T, Ohnishi H, Olefsky JM, Brenner DA, Seki E. Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice. Gastroenterology. 139: 323-34.e7. PMID 20347818 DOI: 10.1053/J.Gastro.2010.03.052 |
0.538 |
|
| 2010 |
Zhong Z, Tsukada S, Rehman H, Parsons CJ, Theruvath TP, Rippe RA, Brenner DA, Lemasters JJ. Inhibition of transforming growth factor-beta/Smad signaling improves regeneration of small-for-size rat liver grafts. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. 16: 181-90. PMID 20104486 DOI: 10.1002/Lt.21966 |
0.312 |
|
| 2010 |
Inokuchi S, Aoyama T, Miura K, Osterreicher CH, Kodama Y, Miyai K, Akira S, Brenner DA, Seki E. Disruption of TAK1 in hepatocytes causes hepatic injury, inflammation, fibrosis, and carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 844-9. PMID 20080763 DOI: 10.1073/Pnas.0909781107 |
0.455 |
|
| 2010 |
Taura K, Miura K, Iwaisako K, Osterreicher CH, Kodama Y, Penz-Osterreicher M, Brenner DA. Hepatocytes do not undergo epithelial-mesenchymal transition in liver fibrosis in mice. Hepatology (Baltimore, Md.). 51: 1027-36. PMID 20052656 DOI: 10.1002/Hep.23368 |
0.423 |
|
| 2010 |
Moreno M, Gonzalo T, Kok RJ, Sancho-Bru P, van Beuge M, Swart J, Prakash J, Temming K, Fondevila C, Beljaars L, Lacombe M, van der Hoeven P, Arroyo V, Poelstra K, Brenner DA, et al. Reduction of advanced liver fibrosis by short-term targeted delivery of an angiotensin receptor blocker to hepatic stellate cells in rats. Hepatology (Baltimore, Md.). 51: 942-52. PMID 20044807 DOI: 10.1002/Hep.23419 |
0.463 |
|
| 2010 |
Sancho-Bru P, Juez E, Moreno M, Khurdayan V, Morales-Ruiz M, Colmenero J, Arroyo V, Brenner DA, Ginès P, Bataller R. Hepatocarcinoma cells stimulate the growth, migration and expression of pro-angiogenic genes in human hepatic stellate cells. Liver International : Official Journal of the International Association For the Study of the Liver. 30: 31-41. PMID 19929904 DOI: 10.1111/J.1478-3231.2009.02161.X |
0.386 |
|
| 2010 |
Scholten D, Scholten A, Östereicher C, Brenner DA, Kisseleva T. 981 EPITHELIAL-TO-MESENCHYMAL TRANSITION (EMT) IN CHOLANGIOCYTES DOES NOT CONTRIBUTE TO THE POPULATION OF α-SMA+ MYOFIBROBLASTS IN EXPERIMENTAL MODELS OF LIVER FIBROSIS Journal of Hepatology. 52. DOI: 10.1016/S0168-8278(10)60982-8 |
0.379 |
|
| 2010 |
Miura K, Inokuchi S, Ohnishi H, Brenner DA, Seki E. 74 Toll-Like Receptor (TLR) 2 in Kupffer Cells Plays a Crucial Role in the Development of Steatohepatitis in Mice Gastroenterology. 138. DOI: 10.1016/S0016-5085(10)63571-8 |
0.363 |
|
| 2010 |
Yan AW, Brandl J, Torralba M, Fouts DE, Schott E, Tsukamoto H, Nelson KE, Brenner DA, Schnabl B. 3 Downregulation of Anti-Microbial Proteins Regenerating Islet-Derived 3 Beta (Reg3b) and Gamma (Reg3g) Contributes to Enteric Dysbiosis in Alcoholic Liver Disease Gastroenterology. 138: S-773. DOI: 10.1016/S0016-5085(10)63564-0 |
0.586 |
|
| 2009 |
Brafman DA, de Minicis S, Seki E, Shah KD, Teng D, Brenner D, Willert K, Chien S. Investigating the role of the extracellular environment in modulating hepatic stellate cell biology with arrayed combinatorial microenvironments. Integrative Biology : Quantitative Biosciences From Nano to Macro. 1: 513-24. PMID 20023766 DOI: 10.1039/B912926J |
0.416 |
|
| 2009 |
Brenner DA. Molecular pathogenesis of liver fibrosis. Transactions of the American Clinical and Climatological Association. 120: 361-8. PMID 19768189 |
0.372 |
|
| 2009 |
Osterreicher CH, Taura K, De Minicis S, Seki E, Penz-Osterreicher M, Kodama Y, Kluwe J, Schuster M, Oudit GY, Penninger JM, Brenner DA. Angiotensin-converting-enzyme 2 inhibits liver fibrosis in mice. Hepatology (Baltimore, Md.). 50: 929-38. PMID 19650157 DOI: 10.1002/Hep.23104 |
0.474 |
|
| 2009 |
Colmenero J, Bataller R, Sancho-Bru P, Domínguez M, Moreno M, Forns X, Bruguera M, Arroyo V, Brenner DA, Ginès P. Effects of losartan on hepatic expression of nonphagocytic NADPH oxidase and fibrogenic genes in patients with chronic hepatitis C American Journal of Physiology - Gastrointestinal and Liver Physiology. 297. PMID 19628656 DOI: 10.1152/Ajpgi.00162.2009 |
0.468 |
|
| 2009 |
Seki E, De Minicis S, Gwak GY, Kluwe J, Inokuchi S, Bursill CA, Llovet JM, Brenner DA, Schwabe RF. CCR1 and CCR5 promote hepatic fibrosis in mice. The Journal of Clinical Investigation. 119: 1858-70. PMID 19603542 DOI: 10.1172/Jci37444 |
0.486 |
|
| 2009 |
Kodama Y, Kisseleva T, Iwaisako K, Miura K, Taura K, De Minicis S, Osterreicher CH, Schnabl B, Seki E, Brenner DA. c-Jun N-terminal kinase-1 from hematopoietic cells mediates progression from hepatic steatosis to steatohepatitis and fibrosis in mice. Gastroenterology. 137: 1467-1477.e5. PMID 19549522 DOI: 10.1053/J.Gastro.2009.06.045 |
0.633 |
|
| 2009 |
Seki E, de Minicis S, Inokuchi S, Taura K, Miyai K, van Rooijen N, Schwabe RF, Brenner DA. CCR2 promotes hepatic fibrosis in mice. Hepatology (Baltimore, Md.). 50: 185-97. PMID 19441102 DOI: 10.1002/Hep.22952 |
0.448 |
|
| 2009 |
Kodama Y, Taura K, Miura K, Schnabl B, Osawa Y, Brenner DA. Antiapoptotic Effect of c-Jun N-terminal Kinase-1 through Mcl-1 Stabilization in TNF-Induced Hepatocyte Apoptosis Gastroenterology. 136: 1423-1434. PMID 19249395 DOI: 10.1053/J.Gastro.2008.12.064 |
0.612 |
|
| 2009 |
Brandl K, Rutschmann S, Li X, Du X, Xiao N, Schnabl B, Brenner DA, Beutler B. Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response Proceedings of the National Academy of Sciences of the United States of America. 106: 3300-3305. PMID 19202076 DOI: 10.1073/Pnas.0813036106 |
0.523 |
|
| 2009 |
Paik YH, Kim JK, Lee JI, Kang SH, Kim DY, An SH, Lee SJ, Lee DK, Han KH, Chon CY, Lee SI, Lee KS, Brenner DA. Celecoxib induces hepatic stellate cell apoptosis through inhibition of Akt activation and suppresses hepatic fibrosis in rats Gut. 58: 1517-1527. PMID 19201774 DOI: 10.1136/Gut.2008.157420 |
0.425 |
|
| 2009 |
Kodama Y, Brenner DA. c‐Jun N‐terminal kinase signaling in the pathogenesis of nonalcoholic fatty liver disease: Multiple roles in multiple steps Hepatology. 49: 6-8. PMID 19111006 DOI: 10.1002/Hep.22710 |
0.401 |
|
| 2009 |
Gäbele E, Froh M, Arteel GE, Uesugi T, Hellerbrand C, Schölmerich J, Brenner DA, Thurman RG, Rippe RA. TNFalpha is required for cholestasis-induced liver fibrosis in the mouse. Biochemical and Biophysical Research Communications. 378: 348-53. PMID 18996089 DOI: 10.1016/J.Bbrc.2008.10.155 |
0.414 |
|
| 2009 |
Notas G, Kisseleva T, Brenner D. NK and NKT cells in liver injury and fibrosis. Clinical Immunology. 130: 16-26. PMID 18823822 DOI: 10.1016/J.Clim.2008.08.008 |
0.478 |
|
| 2009 |
Miura K, Seki E, Kodama Y, Inokuchi S, Brenner DA. 644 Toll-Like Receptor (TLR) 9 Mediates Steatosis and Fibrosis Through Il1β in Diet-Induced Steatohepatitis in Mice Gastroenterology. 136. DOI: 10.1016/S0016-5085(09)63705-7 |
0.311 |
|
| 2009 |
Osawa Y, Seki E, Brenner DA. Apoptosis in liver injury and liver diseases Essentials of Apoptosis: a Guide For Basic and Clinical Research. 547-564. DOI: 10.1007/978-1-60327-381-7_24 |
0.378 |
|
| 2009 |
Bataller R, Brenner DA. Pathogenesis of Hepatic Fibrosis Textbook of Gastroenterology, Fifth Edition. 1: 658-679. DOI: 10.1002/9781444303254.ch27 |
0.309 |
|
| 2008 |
De Minicis S, Seki E, Oesterreicher C, Schnabl B, Schwabe RF, Brenner DA. Reduced nicotinamide adenine dinucleotide phosphate oxidase mediates fibrotic and inflammatory effects of leptin on hepatic stellate cells. Hepatology (Baltimore, Md.). 48: 2016-26. PMID 19025999 DOI: 10.1002/Hep.22560 |
0.587 |
|
| 2008 |
Lin SL, Kisseleva T, Brenner DA, Duffield JS. Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney. The American Journal of Pathology. 173: 1617-27. PMID 19008372 DOI: 10.2353/Ajpath.2008.080433 |
0.342 |
|
| 2008 |
Taura K, De Minicis S, Seki E, Hatano E, Iwaisako K, Osterreicher CH, Kodama Y, Miura K, Ikai I, Uemoto S, Brenner DA. Hepatic Stellate Cells Secrete Angiopoietin 1 That Induces Angiogenesis in Liver Fibrosis Gastroenterology. 135: 1729-1738. PMID 18823985 DOI: 10.1053/J.Gastro.2008.07.065 |
0.5 |
|
| 2008 |
Miura K, Taura K, Kodama Y, Schnabl B, Brenner DA. Hepatitis C virus-induced oxidative stress suppresses hepcidin expression through increased histone deacetylase activity. Hepatology (Baltimore, Md.). 48: 1420-9. PMID 18671304 DOI: 10.1002/Hep.22486 |
0.527 |
|
| 2008 |
Schnabl B, Scholten D, Brenner DA. What is the potential role of antifibrotic agents for the treatment of liver disease? Nature Clinical Practice. Gastroenterology & Hepatology. 5: 496-7. PMID 18628735 DOI: 10.1038/Ncpgasthep1200 |
0.636 |
|
| 2008 |
Seki E, Brenner DA. Toll-like receptors and adaptor molecules in liver disease: update. Hepatology. 48: 322-335. PMID 18506843 DOI: 10.1002/Hep.22306 |
0.401 |
|
| 2008 |
Purohit V, Bode JC, Bode C, Brenner DA, Choudhry MA, Hamilton F, Kang YJ, Keshavarzian A, Rao R, Sartor RB, Swanson C, Turner JR. Alcohol, intestinal bacterial growth, intestinal permeability to endotoxin, and medical consequences: Summary of a symposium Alcohol. 42: 349-361. PMID 18504085 DOI: 10.1016/J.Alcohol.2008.03.131 |
0.342 |
|
| 2008 |
Minicis SD, Brenner DA. Oxidative stress in alcoholic liver disease: Role of NADPH oxidase complex Journal of Gastroenterology and Hepatology. 23. PMID 18336675 DOI: 10.1111/J.1440-1746.2007.05277.X |
0.459 |
|
| 2008 |
Adachi M, Brenner DA. High molecular weight adiponectin inhibits proliferation of hepatic stellate cells via activation of adenosine monophosphate–activated protein kinase† Hepatology. 47: 677-685. PMID 18220291 DOI: 10.1002/Hep.21991 |
0.412 |
|
| 2008 |
Iimuro Y, Brenner DA. Matrix Metalloproteinase Gene Delivery for Liver Fibrosis Pharmaceutical Research. 25: 249-258. PMID 17577645 DOI: 10.1007/S11095-007-9311-7 |
0.449 |
|
| 2008 |
Seki E, Minicis SD, Schwabe RF, Brenner DA. M1565 The Role of Ccr2 in Hepatic Fibrosis and Cancer Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)63712-9 |
0.33 |
|
| 2008 |
Kisseleva T, Notas G, Taura K, Kodama Y, Minicis SD, Kramer M, Hesson DP, Pelura T, Brenner DA. 578 Human Serum Amyloid P (Hsap) Inhibits Bile Duct Ligation Induced Liver Fibrosis in Mice Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)63586-6 |
0.425 |
|
| 2008 |
Adachi M, Seki E, Hibi T, Brenner DA. 364 High Molecular Weight Adiponectin Inhibits Proliferation of Hepatic Stellate Cells Via Activation of AMP-Activated Protein Kinase (Ampk) Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)63570-2 |
0.352 |
|
| 2008 |
Minicis SD, Seki E, Oesterreicher C, Kodama Y, Kluwe J, Schwabe RF, Brenner DA. 362 Phagocytic and Non-Phagocytic NADPH-Oxidase Isoforms Differentially Regulate Fibrosis But Not Steatosis in the Liver Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)63568-4 |
0.459 |
|
| 2008 |
Minicis SD, Seki E, Marzioni M, Osterreicher CH, Kodama Y, Kluwe J, Schwabe RF, Benedetti A, Brenner DA. Phagocytic and non-phagocytic NADPH-oxidase isoforms differentially regulate fibrosis but not steatosis in the liver Digestive and Liver Disease. 40. DOI: 10.1016/J.Dld.2008.07.165 |
0.459 |
|
| 2008 |
De Minicis S, Brafman D, Marzioni M, Seki E, Willert K, Chien S, Benedetti A, Brenner DA. Extracellular matrix combinations differentially modulate hepatic stellate cell biology Digestive and Liver Disease. 40: A132-A133. DOI: 10.1016/J.Dld.2008.07.164 |
0.346 |
|
| 2007 |
Sancho-Bru P, Bataller R, Fernandez-Varo G, Moreno M, Ramalho LN, Colmenero J, Marí M, Clària J, Jiménez W, Arroyo V, Brenner DA, Ginès P. Bradykinin Attenuates Hepatocellular Damage and Fibrosis in Rats With Chronic Liver Injury Gastroenterology. 133: 2019-2028. PMID 18054572 DOI: 10.1053/J.Gastro.2007.09.023 |
0.495 |
|
| 2007 |
Seki E, De Minicis S, Osterreicher CH, Kluwe J, Osawa Y, Brenner DA, Schwabe RF. TLR4 enhances TGF-beta signaling and hepatic fibrosis. Nature Medicine. 13: 1324-32. PMID 17952090 DOI: 10.1038/Nm1663 |
0.381 |
|
| 2007 |
Miura K, Yoshino R, Hirai Y, Goto T, Ohshima S, Mikami K, Yoneyama K, Watanabe D, Sato M, Senoo H, Kodama Y, Osawa Y, Brenner DA, Watanabe S. Epimorphin, a morphogenic protein, induces proteases in rodent hepatocytes through NF-kappaB. Journal of Hepatology. 47: 834-43. PMID 17935821 DOI: 10.1016/J.Jhep.2007.07.024 |
0.42 |
|
| 2007 |
Tacke F, Trautwein C, Yagmur E, Hellerbrand C, Wiest R, Brenner DA, Schnabl B. Up-regulated eotaxin plasma levels in chronic liver disease patients indicate hepatic inflammation, advanced fibrosis and adverse clinical course. Journal of Gastroenterology and Hepatology. 22: 1256-64. PMID 17688666 DOI: 10.1111/J.1440-1746.2006.04621.X |
0.612 |
|
| 2007 |
Mencin A, Seki E, Osawa Y, Kodama Y, Minicis SD, Knowles M, Brenner DA. Alpha-1 antitrypsin Z protein (PiZ) increases hepatic fibrosis in a murine model of cholestasis. Hepatology. 46: 1443-1452. PMID 17668872 DOI: 10.1002/Hep.21832 |
0.474 |
|
| 2007 |
Schwabe RF, Brenner DA. Nuclear Factor-κB in the Liver: Friend or Foe? Gastroenterology. 132: 2601-2604. PMID 17570232 DOI: 10.1053/J.Gastro.2007.04.058 |
0.421 |
|
| 2007 |
Kisseleva T, Brenner DA. Role of hepatic stellate cells in fibrogenesis and the reversal of fibrosis Journal of Gastroenterology and Hepatology. 22. PMID 17567473 DOI: 10.1111/J.1440-1746.2006.04658.X |
0.486 |
|
| 2007 |
Seki E, Brenner DA. The role of NF-κB in hepatocarcinogenesis: Promoter or suppressor? Journal of Hepatology. 47: 307-309. PMID 17566588 DOI: 10.1016/J.Jhep.2007.05.006 |
0.463 |
|
| 2007 |
Minicis SD, Brenner DA. NOX in liver fibrosis. Archives of Biochemistry and Biophysics. 462: 266-272. PMID 17531188 DOI: 10.1016/J.Abb.2007.04.016 |
0.493 |
|
| 2007 |
Osterreicher CH, Brenner DA. The genetics of nonalcoholic fatty liver disease. Annals of Hepatology. 6: 83-8. PMID 17519829 |
0.302 |
|
| 2007 |
De Minicis S, Seki E, Uchinami H, Kluwe J, Zhang Y, Brenner DA, Schwabe RF. Gene expression profiles during hepatic stellate cell activation in culture and in vivo. Gastroenterology. 132: 1937-46. PMID 17484886 DOI: 10.1053/J.Gastro.2007.02.033 |
0.416 |
|
| 2007 |
Tacke F, Gäbele E, Bataille F, Schwabe RF, Hellerbrand C, Klebl F, Straub RH, Luedde T, Manns MP, Trautwein C, Brenner DA, Schölmerich J, Schnabl B. Bone morphogenetic protein 7 is elevated in patients with chronic liver disease and exerts fibrogenic effects on human hepatic stellate cells. Digestive Diseases and Sciences. 52: 3404-15. PMID 17415633 DOI: 10.1007/S10620-007-9758-8 |
0.624 |
|
| 2007 |
Adachi M, Osawa Y, Uchinami H, Kitamura T, Accili D, Brenner DA. The forkhead transcription factor FoxO1 regulates proliferation and transdifferentiation of hepatic stellate cells. Gastroenterology. 132: 1434-46. PMID 17408630 DOI: 10.1053/J.Gastro.2007.01.033 |
0.424 |
|
| 2007 |
Osterreicher CH, Stickel F, Brenner DA. Genomics of liver fibrosis and cirrhosis. Seminars in Liver Disease. 27: 28-43. PMID 17295175 DOI: 10.1055/S-2006-960169 |
0.406 |
|
| 2007 |
Österreicher CH, Brenner DA. The genetics of nonalcoholic fatty liver disease Annals of Hepatology. 6: 83-88. DOI: 10.1016/S1665-2681(19)31936-2 |
0.417 |
|
| 2007 |
Siegmund SY, Qian T, Minicis Sd, Harvey-White J, Kunos G, Vinod KY, Hungund B, Brenner DA, Schwabe RF. [339] The Endocannabinoid 2-Arachidonoyl Glycerol Induces Apoptosis In Primary Hepatic Stellate Cells Via Membrane Cholesterol And Mitochondrial Ros Production Independently Of Cannabinoid-Receptors Or Nadph Oxidase Activation Journal of Hepatology. 46. DOI: 10.1016/S0168-8278(07)61937-0 |
0.328 |
|
| 2006 |
Osawa Y, Seki E, Adachi M, Taura K, Kodama Y, Siegmund SV, Schwabe RF, Brenner DA. Systemic mediators induce fibrogenic effects in normal liver after partial bile duct ligation. Liver International. 26: 1138-1147. PMID 17032415 DOI: 10.1111/J.1478-3231.2006.01346.X |
0.433 |
|
| 2006 |
Kisseleva T, Brenner DA. Hepatic stellate cells and the reversal of fibrosis. Journal of Gastroenterology and Hepatology. 21. PMID 16958681 DOI: 10.1111/J.1440-1746.2006.04584.X |
0.497 |
|
| 2006 |
Uchinami H, Seki E, Brenner DA, D'Armiento J. Loss of MMP 13 attenuates murine hepatic injury and fibrosis during cholestasis. Hepatology (Baltimore, Md.). 44: 420-9. PMID 16871591 DOI: 10.1002/Hep.21268 |
0.444 |
|
| 2006 |
Kisseleva T, Uchinami H, Feirt N, Quintana-Bustamante O, Segovia JC, Schwabe RF, Brenner DA. Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis. Journal of Hepatology. 45: 429-438. PMID 16846660 DOI: 10.1016/J.Jhep.2006.04.014 |
0.462 |
|
| 2006 |
De Minicis S, Bataller R, Brenner DA. NADPH Oxidase in the Liver: Defensive, Offensive, or Fibrogenic? Gastroenterology. 131: 272-275. PMID 16831609 DOI: 10.1053/J.Gastro.2006.05.048 |
0.461 |
|
| 2006 |
Sancho-Bru P, Bataller R, Colmenero J, Gasull X, Moreno M, Arroyo V, Brenner DA, Ginès P. Norepinephrine induces calcium spikes and proinflammatory actions in human hepatic stellate cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 291: G877-84. PMID 16782692 DOI: 10.1152/Ajpgi.00537.2005 |
0.417 |
|
| 2006 |
Schwabe RF, Seki E, Brenner DA. Toll-like receptor signaling in the liver. Gastroenterology. 130: 1886-1900. PMID 16697751 DOI: 10.1053/J.Gastro.2006.01.038 |
0.418 |
|
| 2006 |
Lehnert M, Uehara T, Bradford BU, Lind H, Zhong Z, Brenner DA, Marzi I, Lemasters JJ. Lipopolysaccharide-binding protein modulates hepatic damage and the inflammatory response after hemorrhagic shock and resuscitation. American Journal of Physiology. Gastrointestinal and Liver Physiology. 291: G456-63. PMID 16614372 DOI: 10.1152/Ajpgi.00480.2005 |
0.338 |
|
| 2006 |
Lehmann TG, Luedde T, Schwabe RF, Bunzendahl H, Samulski RJ, Lemasters JJ, Brenner DA. Minimizing oxidative stress by gene delivery of superoxide dismutase accelerates regeneration after transplantation of reduced-size livers in the rat. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. 12: 550-9. PMID 16555330 DOI: 10.1002/Lt.20632 |
0.396 |
|
| 2006 |
Schwabe RF, Brenner DA. Mechanisms of Liver Injury. I. TNF-α-induced liver injury: role of IKK, JNK, and ROS pathways American Journal of Physiology-Gastrointestinal and Liver Physiology. 290. PMID 16537970 DOI: 10.1152/Ajpgi.00422.2005 |
0.452 |
|
| 2006 |
Purohit V, Brenner DA. Mechanisms of alcohol-induced hepatic fibrosis: a summary of the Ron Thurman Symposium. Hepatology (Baltimore, Md.). 43: 872-8. PMID 16502397 DOI: 10.1002/hep.21107 |
0.306 |
|
| 2006 |
Siegmund S, Seki E, Uchinami H, Cravatt B, Brenner D, Schwabe R. Endocannabinoid Degradation and Oxidative Defense Mechanisms Determine Anandamide-induced Cell Death in Liver Cell Populations Zeitschrift FüR Gastroenterologie. 44. DOI: 10.1055/S-2006-931661 |
0.38 |
|
| 2006 |
Siegmund S, Qian T, Harvey-White J, Kunos G, Brenner D, Schwabe R. The Endocannabinoid 2-Arachidonoyl Glycerol Induces Apoptosis in Primary Hepatic Stellate Cells and Is Upregulated During Hepatic Fibrogenesis Zeitschrift Fur Gastroenterologie. 44. DOI: 10.1055/S-2006-931625 |
0.42 |
|
| 2006 |
Sancho-Bru P, Bataller R, Juez E, Khurdayan V, Moreno M, Colmenero J, Arroyo V, Brenner DA, Ginès P. 58 Hepatocarcinoma cells stimulate proliferation and migration and inhibit fibrogenic actions in human hepatic stellate cells: Regulation by hepatitis C virus proteins Journal of Hepatology. 44. DOI: 10.1016/S0168-8278(06)80059-0 |
0.384 |
|
| 2005 |
Siegmund SV, Dooley S, Brenner DA. Molecular mechanisms of alcohol-induced hepatic fibrosis. Digestive Diseases. 23: 264-274. PMID 16508291 DOI: 10.1159/000090174 |
0.439 |
|
| 2005 |
Adachi M, Brenner DA. Clinical syndromes of alcoholic liver disease. Digestive Diseases. 23: 255-263. PMID 16508290 DOI: 10.1159/000090173 |
0.413 |
|
| 2005 |
Siegmund SV, Brenner DA. Molecular pathogenesis of alcohol-induced hepatic fibrosis. Alcoholism: Clinical and Experimental Research. 29. PMID 16344593 DOI: 10.1097/01.Alc.0000189275.97419.58 |
0.486 |
|
| 2005 |
Osawa Y, Hannun YA, Proia RL, Brenner DA. Roles of AKT and sphingosine kinase in the antiapoptotic effects of bile duct ligation in mouse liver. Hepatology (Baltimore, Md.). 42: 1320-8. PMID 16317686 DOI: 10.1002/Hep.20967 |
0.489 |
|
| 2005 |
Stefanovic L, Brenner DA, Stefanovic B. Direct hepatotoxic effect of KC chemokine in the liver without infiltration of neutrophils. Experimental Biology and Medicine (Maywood, N.J.). 230: 573-86. PMID 16118408 DOI: 10.1177/153537020523000809 |
0.501 |
|
| 2005 |
Bataller R, Sancho-Bru P, Ginès P, Brenner DA. Liver fibrogenesis: A new role for the renin-angiotensin system Antioxidants and Redox Signaling. 7: 1346-1355. PMID 16115040 DOI: 10.1089/Ars.2005.7.1346 |
0.469 |
|
| 2005 |
Schnabl B, Hu K, Mühlbauer M, Hellerbrand C, Stefanovic B, Brenner DA, Schölmerich J. Zinc finger protein 267 is up-regulated during the activation process of human hepatic stellate cells and functions as a negative transcriptional regulator of MMP-10 Biochemical and Biophysical Research Communications. 335: 87-96. PMID 16054593 DOI: 10.1016/J.Bbrc.2005.07.043 |
0.547 |
|
| 2005 |
Yang L, Bataller R, Dulyx J, Coffman TM, Ginès P, Rippe RA, Brenner DA. Attenuated hepatic inflammation and fibrosis in angiotensin type 1a receptor deficient mice Journal of Hepatology. 43: 317-323. PMID 15964094 DOI: 10.1016/J.Jhep.2005.02.034 |
0.421 |
|
| 2005 |
Osawa Y, Uchinami H, Bielawski J, Schwabe RF, Hannun YA, Brenner DA. Roles for C16-ceramide and sphingosine 1-phosphate in regulating hepatocyte apoptosis in response to tumor necrosis factor-alpha. The Journal of Biological Chemistry. 280: 27879-87. PMID 15946935 DOI: 10.1074/Jbc.M503002200 |
0.323 |
|
| 2005 |
Yang L, Magness ST, Bataller R, Rippe RA, Brenner DA. NF-κB activation in Kupffer cells after partial hepatectomy American Journal of Physiology - Gastrointestinal and Liver Physiology. 289. PMID 15905413 DOI: 10.1152/Ajpgi.00526.2004 |
0.423 |
|
| 2005 |
Uehara T, Bennett B, Sakata ST, Satoh Y, Bilter GK, Westwick JK, Brenner DA. JNK mediates hepatic ischemia reperfusion injury. Journal of Hepatology. 42: 850-9. PMID 15885356 DOI: 10.1016/J.Jhep.2005.01.030 |
0.384 |
|
| 2005 |
Siegmund SV, Uchinami H, Osawa Y, Brenner DA, Schwabe RF. Anandamide induces necrosis in primary hepatic stellate cells Hepatology. 41: 1085-1095. PMID 15841466 DOI: 10.1002/Hep.20667 |
0.368 |
|
| 2005 |
Bataller R, Gäbele E, Parsons CJ, Morris T, Yang L, Schoonhoven R, Brenner DA, Rippe RA. Systemic infusion of angiotensin II exacerbates liver fibrosis in bile duct-ligated rats. Hepatology (Baltimore, Md.). 41: 1046-55. PMID 15841463 DOI: 10.1002/Hep.20665 |
0.41 |
|
| 2005 |
Luedde T, Assmus U, Wüstefeld T, Meyer Zu Vilsendorf A, Roskams T, Schmidt-Supprian M, Rajewsky K, Brenner DA, Manns MP, Pasparakis M, Trautwein C. Deletion of IKK2 in hepatocytes does not sensitize these cells to TNF-induced apoptosis but protects from ischemia/reperfusion injury Journal of Clinical Investigation. 115: 849-859. PMID 15776110 DOI: 10.1172/Jci23493 |
0.418 |
|
| 2005 |
Bataller R, Brenner DA. Liver fibrosis. The Journal of Clinical Investigation. 115: 209-18. PMID 15690074 DOI: 10.1172/JCI24282 |
0.396 |
|
| 2005 |
Gäbele E, Reif S, Tsukada S, Bataller R, Yata Y, Morris T, Schrum LW, Brenner DA, Rippe RA. The role of p70S6K in hepatic stellate cell collagen gene expression and cell proliferation Journal of Biological Chemistry. 280: 13374-13382. PMID 15677443 DOI: 10.1074/Jbc.M409444200 |
0.387 |
|
| 2005 |
Sanz S, Pucilowska JB, Liu S, RodrÃguez-Ortigosa CM, Lund PK, Brenner DA, Fuller CR, Simmons JG, Pardo A, MartÃnez-Chantar ML, Fagin JA, Prieto J. Expression of insulin-like growth factor I by activated hepatic stellate cells reduces fibrogenesis and enhances regeneration after liver injury. Gut. 54: 134-41. PMID 15591519 DOI: 10.1136/gut.2003.024505 |
0.341 |
|
| 2005 |
Bataller R, Brenner DA. Erratum: Liver fibrosis (Journal of Clinical Investigation (2005) 115 (209-218) DOI:10.1172/JCI200524282) Journal of Clinical Investigation. 115. DOI: 10.1172/Jci200524282C1 |
0.422 |
|
| 2004 |
Harada N, Hatano E, Koizumi N, Nitta T, Yoshida M, Yamamoto N, Brenner DA, Yamaoka Y. Akt activation protects rat liver from ischemia/reperfusion injury Journal of Surgical Research. 121: 159-170. PMID 15501455 DOI: 10.1016/J.Jss.2004.04.016 |
0.384 |
|
| 2004 |
Rippe RA, Brenner DA. From quiescence to activation: Gene regulation in hepatic stellate cells Gastroenterology. 127: 1260-1262. PMID 15481004 DOI: 10.1053/J.Gastro.2004.08.028 |
0.394 |
|
| 2004 |
Magness ST, Bataller R, Yang L, Brenner DA. A dual reporter gene transgenic mouse demonstrates heterogeneity in hepatic fibrogenic cell populations Hepatology. 40: 1151-1159. PMID 15389867 DOI: 10.1002/Hep.20427 |
0.363 |
|
| 2004 |
Parsons CJ, Bradford BU, Pan CQ, Cheung E, Schauer M, Knorr A, Krebs B, Kraft S, Zahn S, Brocks B, Feirt N, Mei B, Cho MS, Ramamoorthi R, Roldan G, ... ... Brenner DA, et al. Antifibrotic effects of a tissue inhibitor of metalloproteinase-1 antibody on established liver fibrosis in rats. Hepatology (Baltimore, Md.). 40: 1106-15. PMID 15389776 DOI: 10.1002/Hep.20425 |
0.391 |
|
| 2004 |
Uehara T, Xi Peng X, Bennett B, Satoh Y, Friedman G, Currin R, Brenner DA, Lemasters J. c-Jun N-terminal kinase mediates hepatic injury after rat liver transplantation. Transplantation. 78: 324-32. PMID 15316358 DOI: 10.1097/01.Tp.0000128859.42696.28 |
0.392 |
|
| 2004 |
Magness ST, Jijon H, Van Houten Fisher N, Sharpless NE, Brenner DA, Jobin C. In vivo pattern of lipopolysaccharide and anti-CD3-induced NF-κB activation using a novel gene-targeted enhanced GFP reporter gene mouse Journal of Immunology. 173: 1561-1570. PMID 15265883 DOI: 10.4049/Jimmunol.173.3.1561 |
0.34 |
|
| 2004 |
Black D, Bird MA, Hayden M, Schrum LW, Lange P, Samson C, Hatano E, Rippe RA, Brenner DA, Behrns KE. TNF alpha-induced hepatocyte apoptosis is associated with alterations of the cell cycle and decreased stem loop binding protein. Surgery. 135: 619-28. PMID 15179368 DOI: 10.1016/J.Surg.2003.11.004 |
0.329 |
|
| 2004 |
Black D, Bird MA, Samson CM, Lyman S, Lange PA, Schrum LW, Qian T, Lemasters JJ, Brenner DA, Rippe RA, Behrns KE. Primary cirrhotic hepatocytes resist TGFbeta-induced apoptosis through a ROS-dependent mechanism. Journal of Hepatology. 40: 942-51. PMID 15158334 DOI: 10.1016/J.Jhep.2004.02.031 |
0.372 |
|
| 2004 |
Schwabe RF, Uchinami H, Qian T, Bennett BL, Lemasters JJ, Brenner DA. Differential requirement for c-Jun NH2-terminal kinase in TNFalpha- and Fas-mediated apoptosis in hepatocytes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 720-2. PMID 14766793 DOI: 10.1096/Fj.03-0771Fje |
0.346 |
|
| 2004 |
Bataller R, Paik YH, Lindquist JN, Lemasters JJ, Brenner DA. Hepatitis C virus core and nonstructural proteins induce fibrogenic effects in hepatic stellate cells. Gastroenterology. 126: 529-40. PMID 14762790 DOI: 10.1053/J.Gastro.2003.11.018 |
0.359 |
|
| 2004 |
Stefanovic B, Stefanovic L, Schnabl B, Bataller R, Brenner DA. TRAM2 protein interacts with endoplasmic reticulum Ca2+ pump Serca2b and is necessary for collagen type I synthesis. Molecular and Cellular Biology. 24: 1758-68. PMID 14749390 DOI: 10.1128/Mcb.24.4.1758-1768.2004 |
0.551 |
|
| 2004 |
Brenner DA. Molecular Pathogenesis of Alcoholic Liver Disease Kanzo. 45. DOI: 10.2957/Kanzo.45.Supplement3_A524 |
0.401 |
|
| 2004 |
Brenner DA, Sigmund S. Pathogenesis of alcoholic hepatitis Journal of Gastroenterology and Hepatology. 19. DOI: 10.1111/J.1440-1746.2004.03679.X |
0.466 |
|
| 2004 |
Bataller R, Ros J, Jimenez W, Brenner DA. 308 Anandamide, an endogenous cannabinoid, inhibits contraction, proliferation and migration of human hepatic stellate cells Journal of Hepatology. 40: 94-95. DOI: 10.1016/S0168-8278(04)90308-X |
0.385 |
|
| 2004 |
Sancho-Bru P, Bataller R, Ginès P, Colmenero J, Khurdayan V, Brenner DA, Arroyo V, Rodés J. 18 Norepinephrine induces inflammatory actions and calcium mobilization in human hepatic stellate cells through alpha receptors Journal of Hepatology. 40: 8. DOI: 10.1016/S0168-8278(04)90018-9 |
0.442 |
|
| 2003 |
Imose M, Nagaki M, Naiki T, Osawa Y, Brenner DA, Asano T, Hayashi H, Kato T, Moriwaki H. Inhibition of nuclear factor κB and phosphatidylinositol 3-kinase/Akt is essential for massive hepatocyte apoptosis induced by tumor necrosis factor α in mice Liver International. 23: 386-396. PMID 14708901 DOI: 10.1034/J.1478-3231.2003.00867.X |
0.381 |
|
| 2003 |
Bataller R, Schwabe RF, Choi YH, Yang L, Paik YH, Lindquist J, Qian T, Schoonhoven R, Hagedorn CH, Lemasters JJ, Brenner DA. NADPH oxidase signal transduces angiotensin II in hepatic stellate cells and is critical in hepatic fibrosis. The Journal of Clinical Investigation. 112: 1383-94. PMID 14597764 DOI: 10.1172/Jci18212 |
0.397 |
|
| 2003 |
Lehmann TG, Wheeler MD, Froh M, Schwabe RF, Bunzendahl H, Samulski RJ, Lemasters JJ, Brenner DA, Thurman RG. Effects of three superoxide dismutase genes delivered with an adenovirus on graft function after transplantation of fatty livers in the rat. Transplantation. 76: 28-37. PMID 12865782 DOI: 10.1097/01.Tp.0000065299.29900.17 |
0.352 |
|
| 2003 |
Schwabe RF, Bataller R, Brenner DA. Human hepatic stellate cells express CCR5 and RANTES to induce proliferation and migration American Journal of Physiology - Gastrointestinal and Liver Physiology. 285. PMID 12829440 DOI: 10.1152/Ajpgi.00215.2003 |
0.408 |
|
| 2003 |
Kweon YO, Paik YH, Schnabl B, Qian T, Lemasters JJ, Brenner DA. Gliotoxin-mediated apoptosis of activated human hepatic stellate cells. Journal of Hepatology. 39: 38-46. PMID 12821042 DOI: 10.1016/S0168-8278(03)00178-8 |
0.645 |
|
| 2003 |
Bataller R, Gäbele E, Schoonhoven R, Morris T, Lehnert M, Yang L, Brenner DA, Rippe RA. Prolonged infusion of angiotensin II into normal rats induces stellate cell activation and proinflammatory events in liver American Journal of Physiology - Gastrointestinal and Liver Physiology. 285. PMID 12773299 DOI: 10.1152/Ajpgi.00037.2003 |
0.394 |
|
| 2003 |
Oh KW, Qian T, Brenner DA, Lemasters JJ. Salicylate enhances necrosis and apoptosis mediated by the mitochondrial permeability transition. Toxicological Sciences : An Official Journal of the Society of Toxicology. 73: 44-52. PMID 12700412 DOI: 10.1093/Toxsci/Kfg045 |
0.307 |
|
| 2003 |
Osawa Y, Nagaki M, Banno Y, Brenner DA, Nozawa Y, Moriwaki H, Nakashima S. Expression of the NF-κB Target Gene X-Ray-Inducible Immediate Early Response Factor-1 Short Enhances TNF-α-Induced Hepatocyte Apoptosis by Inhibiting Akt Activation Journal of Immunology. 170: 4053-4060. PMID 12682234 DOI: 10.4049/Jimmunol.170.8.4053 |
0.31 |
|
| 2003 |
Nishio T, Iimuro Y, Nitta T, Harada N, Yoshida M, Hirose T, Yamamoto N, Morimoto T, Brenner DA, Yamaoka Y. Increased expression of collagenase in the liver induces hepatocyte proliferation with cytoplasmic accumulation of β-catenin in the rat Journal of Hepatology. 38: 468-475. PMID 12663239 DOI: 10.1016/S0168-8278(03)00013-8 |
0.487 |
|
| 2003 |
Schnabl B, Purbeck CA, Choi YH, Hagedorn CH, Brenner D. Replicative senescence of activated human hepatic stellate cells is accompanied by a pronounced inflammatory but less fibrogenic phenotype. Hepatology (Baltimore, Md.). 37: 653-64. PMID 12601363 DOI: 10.1053/Jhep.2003.50097 |
0.59 |
|
| 2003 |
Bataller R, North KE, Brenner DA. Genetic polymorphisms and the progression of liver fibrosis: A critical appraisal Hepatology. 37: 493-503. PMID 12601343 DOI: 10.1053/Jhep.2003.50127 |
0.462 |
|
| 2003 |
Iimuro Y, Nishio T, Morimoto T, Nitta T, Stefanovic B, Choi SK, Brenner DA, Yamaoka Y. Delivery of matrix metalloproteinase-1 attenuates established liver fibrosis in the rat. Gastroenterology. 124: 445-58. PMID 12557150 DOI: 10.1053/Gast.2003.50063 |
0.406 |
|
| 2003 |
Yata Y, Scanga A, Gillan A, Yang L, Reif S, Breindl M, Brenner DA, Rippe RA. DNase I–hypersensitive sites enhance α1(I) collagen gene expression in hepatic stellate cells Hepatology. 37: 267-276. PMID 12540776 DOI: 10.1053/Jhep.2003.50067 |
0.375 |
|
| 2003 |
Reif S, Lang A, Lindquist JN, Yata Y, Gäbele E, Scanga A, Brenner DA, Rippe RA. The role of focal adhesion kinase-phosphatidylinositol 3-kinase-akt signaling in hepatic stellate cell proliferation and type I collagen expression. Journal of Biological Chemistry. 278: 8083-8090. PMID 12502711 DOI: 10.1074/Jbc.M212927200 |
0.346 |
|
| 2003 |
Gäbele E, Brenner DA, Rippe RA. Liver fibrosis: signals leading to the amplification of the fibrogenic hepatic stellate cell. Frontiers in Bioscience. 8. PMID 12456323 DOI: 10.2741/887 |
0.48 |
|
| 2003 |
Schwabe RF, Bataller R, Brenner DA, Jijon HB. 1272 Serum amyloid a activates proinflammatory signaling pathways and enhances chemokine secretion in activated human hepatic stellate cells Hepatology. 38: 773-773. DOI: 10.1016/S0270-9139(03)81310-1 |
0.371 |
|
| 2003 |
Osawa Y, Nagaki M, Brenner DA, Moriwaki H. 860 Expression of the NF-kappaB target gene IEX-1S enhances TNF-alpha induced hepatocyte apoptosis by inhibiting AKT activation Hepatology. 38: 574-575. DOI: 10.1016/S0270-9139(03)80902-3 |
0.303 |
|
| 2003 |
ZHONG Z, SCHWABE R, FROH M, YANG L, BRENNER D, BUNZENDAHL H, LEMASTERS J. 658 Supression of regeneration in small-for-size liver grafts is associated with inhibition of cyclin D1 expression: Reversal by plant polyphenols Hepatology. 38: 478-478. DOI: 10.1016/S0270-9139(03)80700-0 |
0.332 |
|
| 2003 |
Yang L, Bataller R, Coffman TM, Rippe RA, Brenner DA. 365 Attenuated liver fibrosis in angiotensin type 1 receptor deficient mice Hepatology. 38: 336-336. DOI: 10.1016/S0270-9139(03)80408-1 |
0.405 |
|
| 2003 |
Benten D, Kumaran V, Joseph B, Brenner DA, Gupta S. 214 Intrasplenically transplanted human hepatic stellate cells (HSC) engraft and survive in the liver of immunodeficient mice for prolonged periods Hepatology. 38: 259-259. DOI: 10.1016/S0270-9139(03)80257-4 |
0.421 |
|
| 2003 |
Rippe RA, Lindquist J, Bataller R, Morris T, Wheeler MD, Brenner DA. 142 Inhibition of phosphatidylinositol 3-kinase activity attenuates the development of experimentally induced liver fibrosis Hepatology. 38: 224-224. DOI: 10.1016/S0270-9139(03)80185-4 |
0.435 |
|
| 2002 |
Osawa Y, Nagaki M, Banno Y, Brenner DA, Asano T, Nozawa Y, Moriwaki H, Nakashima S. Tumor Necrosis Factor Alpha-Induced Interleukin-8 Production via NF-κB and Phosphatidylinositol 3-Kinase/Akt Pathways Inhibits Cell Apoptosis in Human Hepatocytes Infection and Immunity. 70: 6294-6301. PMID 12379708 DOI: 10.1128/Iai.70.11.6294-6301.2002 |
0.317 |
|
| 2002 |
Samson CM, Schrum LW, Bird MA, Lange PA, Brenner DA, Rippe RA, Behrns KE. Transforming growth factor-β1 induces hepatocyte apoptosis by a c-Jun independent mechanism Surgery. 132: 441-449. PMID 12324757 DOI: 10.1067/Msy.2002.125321 |
0.315 |
|
| 2002 |
Magness ST, Maeda N, Brenner DA. An exon 10 deletion in the mouse ferrochelatase gene has a dominant-negative effect and causes mild protoporphyria. Blood. 100: 1470-7. PMID 12149233 DOI: 10.1182/Blood-2001-12-0283 |
0.324 |
|
| 2002 |
Liedtke C, Plümpe J, Kubicka S, Bradham CA, Manns MP, Brenner DA, Trautwein C. Jun kinase modulates tumor necrosis factor-dependent apoptosis in liver cells. Hepatology (Baltimore, Md.). 36: 315-25. PMID 12143039 DOI: 10.1053/Jhep.2002.34615 |
0.372 |
|
| 2002 |
Schwabe RF, Brenner DA. Role of glycogen synthase kinase-3 in TNF-α-induced NF-κB activation and apoptosis in hepatocytes American Journal of Physiology-Gastrointestinal and Liver Physiology. 283. PMID 12065308 DOI: 10.1152/Ajpgi.00016.2002 |
0.38 |
|
| 2002 |
Schnabl B, Choi YH, Olsen JC, Hagedorn CH, Brenner DA. Immortal activated human hepatic stellate cells generated by ectopic telomerase expression. Laboratory Investigation; a Journal of Technical Methods and Pathology. 82: 323-33. PMID 11896211 DOI: 10.1038/Labinvest.3780426 |
0.573 |
|
| 2002 |
Stefanovic B, Schnabl B, Brenner DA. Inhibition of collagen alpha 1(I) expression by the 5' stem-loop as a molecular decoy. The Journal of Biological Chemistry. 277: 18229-37. PMID 11889120 DOI: 10.1074/Jbc.M108065200 |
0.53 |
|
| 2002 |
Luedde T, Trautwein C, Rodriguez ME, Brenner DA, Xiong Y. Cooperation of p18INK4c with p21CIP1/WAF1 and p27KIP1 in liver-regeneration Journal of Hepatology. 36: 19. DOI: 10.1016/S0168-8278(02)80050-2 |
0.448 |
|
| 2002 |
Sanz S, Rodriguez-Ortigosa CM, Lund K, Brenner DA, Prieto J. Insulin-like growth factor type-I (IGF-I) modulates the inflammatory response within the liver Journal of Hepatology. 36: 10. DOI: 10.1016/S0168-8278(02)80026-5 |
0.319 |
|
| 2002 |
Kweon YO, Goodman ZD, Dienstag JL, Schiff ER, Brown NA, Burchardt ER, Schoonhoven R, Brenner DA, Fried MW. Erratum: Decreasing fibrogenesis. An immunohistochemical study of paired liver biopsies following lamivudine therapy for chronic hepatitis B (Journal of Hepatology (2001) 35 (749-755) PII:S0168827801002185) Journal of Hepatology. 36. DOI: 10.1016/S0168-8278(02)00116-2 |
0.397 |
|
| 2002 |
Kim Y, Schwabe RF, Qian T, Lemasters JJ, Brenner DA. TRAIL-mediated apoptosis requires NF-kB inhibition and the mitochondrial permeability transition in human hepatoma cells Hepatology. 36: 1498-1508. DOI: 10.1002/Hep.1840360627 |
0.309 |
|
| 2001 |
Kweon YO, Goodman ZD, Dienstag JL, Schiff ER, Brown NA, Burkhardt E, Schoonhoven R, Brenner DA, Fried MW. Decreasing fibrogenesis: An immunohistochemical study of paired liver biopsies following lamivudine therapy for chronic hepatitis B Journal of Hepatology. 35: 749-755. PMID 11738102 DOI: 10.1016/S0168-8278(01)00218-5 |
0.402 |
|
| 2001 |
Schnabl B, Bradham CA, Bennett BL, Manning AM, Stefanovic B, Brenner DA. TAK1/JNK and p38 have opposite effects on rat hepatic stellate cells. Hepatology (Baltimore, Md.). 34: 953-63. PMID 11679966 DOI: 10.1053/Jhep.2001.28790 |
0.536 |
|
| 2001 |
Bradham CA, Hatano E, Brenner DA. Dominant-negative TAK1 induces c-Myc and G(0) exit in liver. American Journal of Physiology. Gastrointestinal and Liver Physiology. 281: G1279-89. PMID 11668037 DOI: 10.1152/Ajpgi.2001.281.5.G1279 |
0.385 |
|
| 2001 |
Bataller R, Brenner DA. Hepatic stellate cells as a target for the treatment of liver fibrosis Seminars in Liver Disease. 21: 437-451. PMID 11586471 DOI: 10.1055/S-2001-17558 |
0.483 |
|
| 2001 |
Schnabl B, Kweon YO, Frederick JP, Wang XF, Rippe RA, Brenner DA. The role of Smad3 in mediating mouse hepatic stellate cell activation. Hepatology (Baltimore, Md.). 34: 89-100. PMID 11431738 DOI: 10.1053/Jhep.2001.25349 |
0.592 |
|
| 2001 |
Osawa Y, Banno Y, Nagaki M, Brenner DA, Naiki T, Nozawa Y, Nakashima S, Moriwaki H. TNF-α-Induced Sphingosine 1-Phosphate Inhibits Apoptosis Through a Phosphatidylinositol 3-Kinase/Akt Pathway in Human Hepatocytes Journal of Immunology. 167: 173-180. PMID 11418646 DOI: 10.4049/Jimmunol.167.1.173 |
0.313 |
|
| 2001 |
Schwabe RF, Schnabl B, Kweon YO, Brenner DA. CD40 activates NF-κB and c-Jun N-terminal kinase and enhances chemokine secretion on activated human hepatic stellate cells Journal of Immunology. 166: 6812-6819. PMID 11359840 DOI: 10.4049/Jimmunol.166.11.6812 |
0.586 |
|
| 2001 |
Schwabe RF, Bennett BL, Manning AM, Brenner DA. Differential role of IκB kinase 1 and 2 in primary rat hepatocytes Hepatology. 33: 81-90. PMID 11124824 DOI: 10.1053/Jhep.2001.20799 |
0.32 |
|
| 2001 |
Nishiura T, Nishimura T, deSerres S, Nakagawa T, Oi I, Brenner DA, Meyer AA. Activation of Stat3 in the Liver after Burn Injury in Mice: 150. Journal of Burn Care & Rehabilitation. 22. DOI: 10.1097/00004630-200103002-00150 |
0.389 |
|
| 2001 |
Dacosta CM, Simmons JG, Fuller CR, Williams KL, Breindl M, Rippe RA, Brenner DA, Pucilowska JB, Lund PK. Collagen promoter-GFP transgenic mice provide a model to study collagen gene expression during experimental intestinal inflammation and injury in vivo and in vitro Gastroenterology. 120. DOI: 10.1016/S0016-5085(08)80663-4 |
0.309 |
|
| 2001 |
Reif S, Scanga AE, Brenner DA, Rippe RA. The role of AKT in hepatic stellate cell activation Gastroenterology. 120. DOI: 10.1016/S0016-5085(08)80132-1 |
0.42 |
|
| 2000 |
Lang A, Schrum LW, Schoonhoven R, Tuvia S, Solís-Herruzo JA, Tsukamoto H, Brenner DA, Rippe RA. Expression of small heat shock protein alphaB-crystallin is induced after hepatic stellate cell activation. American Journal of Physiology. Gastrointestinal and Liver Physiology. 279: G1333-42. PMID 11093957 DOI: 10.1152/Ajpgi.2000.279.6.G1333 |
0.354 |
|
| 2000 |
Nagaki M, Naiki T, Brenner DA, Osawa Y, Imose M, Hayashi H, Banno Y, Nakashima S, Moriwaki H. Tumor necrosis factor α prevents tumor necrosis factor receptor—mediated mouse hepatocyte apoptosis, but not fas‐mediated apoptosis: Role of nuclear factor‐κB Hepatology. 32: 1272-1279. PMID 11093734 DOI: 10.1053/Jhep.2000.20239 |
0.328 |
|
| 2000 |
Lehmann TG, Wheeler MD, Schwabe RF, Connor HD, Schoonhoven R, Bunzendahl H, Brenner DA, Jude Samulski R, Zhong Z, Thurman RG. Gene delivery of Cu/Zn-superoxide dismutase improves graft function after transplantation of fatty livers in the rat. Hepatology (Baltimore, Md.). 32: 1255-64. PMID 11093732 DOI: 10.1053/Jhep.2000.19814 |
0.373 |
|
| 2000 |
Lang A, Schoonhoven R, Tuvia S, Brenner DA, Rippe RA. Nuclear factor κB in proliferation, activation, and apoptosis in rat hepatic stellate cells Journal of Hepatology. 33: 49-58. PMID 10905586 DOI: 10.1016/S0168-8278(00)80159-2 |
0.359 |
|
| 2000 |
Enomoto N, Ikejima K, Yamashina S, Enomoto A, Nishiura T, Nishimura T, Brenner DA, Schemmer P, Bradford BU, Rivera CA, Zhong Z, Thurman RG. Kupffer cell-derived prostaglandin E2 is involved in alcohol-induced fat accumulation in rat liver American Journal of Physiology - Gastrointestinal and Liver Physiology. 279. PMID 10898751 DOI: 10.1152/Ajpgi.2000.279.1.G100 |
0.378 |
|
| 2000 |
Enomoto N, Ikejima K, Bradford BU, Rivera CA, Kono H, Goto M, Yamashina S, Schemmer P, Kitamura T, Oide H, Takei Y, Hirose M, Shimizu H, Miyazaki A, Brenner DA, et al. Role of Kupffer cells and gut-derived endotoxins in alcoholic liver injury. Journal of Gastroenterology and Hepatology. 15: D20-5. PMID 10759216 DOI: 10.1046/J.1440-1746.2000.02179.X |
0.421 |
|
| 2000 |
Nishiura T, Nishimura T, deSerres S, Godfrey V, Bradham CA, Nakagawa T, Brenner DA, Meyer AA. Gene expression and cytokine and enzyme activation in the liver after a burn injury. The Journal of Burn Care & Rehabilitation. 21: 135-41. PMID 10752746 DOI: 10.1097/00004630-200021020-00009 |
0.406 |
|
| 2000 |
Brenner DA, Waterboer T, Choi SK, Lindquist JN, Stefanovic B, Burchardt E, Yamauchi M, Gillan A, Rippe RA. New aspects of hepatic fibrosis. Journal of Hepatology. 32: 32-8. PMID 10728792 DOI: 10.1016/S0168-8278(00)80413-4 |
0.462 |
|
| 2000 |
Iimuro Y, Bradford BU, Yamashina S, Rusyn I, Nakagami M, Enomoto N, Kono H, Frey W, Forman D, Brenner D, Thurman RG. The glutathione precursor L-2-oxothiazolidine-4-carboxylic acid protects against liver injury due to chronic enteral ethanol exposure in the rat Hepatology. 31: 391-398. PMID 10655262 DOI: 10.1002/Hep.510310219 |
0.328 |
|
| 2000 |
Nishimura T, Nishiura T, deserres S, Nakagawa T, Brenner DA, Meyer AA. Impact of burn injury on hepatic TGF-β1 expression and plasma TGF-β1 levels Journal of Trauma-Injury Infection and Critical Care. 48: 39-44. PMID 10647563 DOI: 10.1097/00005373-200001000-00007 |
0.316 |
|
| 2000 |
Schrum LW, Black D, Iimuro Y, Rippe RA, Brenner DA, Behrns KE. c-Jun does not mediate hepatocyte apoptosis following NFkappaB inhibition and partial hepatectomy. The Journal of Surgical Research. 88: 142-9. PMID 10644480 DOI: 10.1006/Jsre.1999.5784 |
0.353 |
|
| 2000 |
Rhoads JM, Argenzio RA, Chen W, Graves LM, Licato LL, Blikslager AT, Smith J, Gatzy J, Brenner DA. Glutamine metabolism stimulates intestinal cell MAPKs by a CAMP- inhibitable, Raf-independent mechanism Gastroenterology. 118: 90-100. PMID 10611157 DOI: 10.1016/S0016-5085(00)70417-3 |
0.307 |
|
| 2000 |
Pümpe J, Liedtke C, Bradham CA, Brenner DA, Manns MP, Trautwein C. TNFα-dependent Jun kinase activity modulates apoptosis in humanhepatoma cells Journal of Hepatology. 32: 76. DOI: 10.1016/S0168-8278(00)80622-4 |
0.322 |
|
| 2000 |
Liu SL, Sanz S, Pucilowska JB, Fuller CR, Prieto J, Brenner DA, Fagin JA, Lund PK. Stellate cell specific overexpression of IGF-I reduces acute liver damage induced by carbon-tetrachloride in vivo Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)86205-8 |
0.405 |
|
| 2000 |
Schwabe RF, Schnabl B, Brenner DA. CD40 activates NFKB and JNK and enhances IL-8 secretion on human hepatic myofibroblasts Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)86204-6 |
0.541 |
|
| 2000 |
Choi S, Yamauchi M, Stefanovic B, Brenner DA. Lysyl hydroxylase gene expression and collagen cross-linking in normal, acute hepatic failure and cirrhotic human liver Gastroenterology. 118: A988. DOI: 10.1016/S0016-5085(00)86098-9 |
0.41 |
|
| 2000 |
Schnabl B, Lim S, Kweon Y, Wang X, Rippe RA, Brenner DA. The in vivo role of Sma3 in mediating CCl4 induced liver fibrosis Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)86095-3 |
0.653 |
|
| 1999 |
Rusyn I, Bradham CA, Cohn L, Schoonhoven R, Swenberg JA, Brenner DA, Thurman RG. Corn oil rapidly activates nuclear factor-kappaB in hepatic Kupffer cells by oxidant-dependent mechanisms. Carcinogenesis. 20: 2095-100. PMID 10545411 DOI: 10.1093/Carcin/20.11.2095 |
0.34 |
|
| 1999 |
Rippe RA, Schrum LW, Stefanovic B, Solís-Herruzo JA, Brenner DA. NF-kappaB inhibits expression of the alpha1(I) collagen gene. Dna and Cell Biology. 18: 751-61. PMID 10541434 DOI: 10.1089/104454999314890 |
0.309 |
|
| 1999 |
Enomoto N, Yamashina S, Schemmer P, Rivera CA, Bradford BU, Enomoto A, Brenner DA, Thurman RG. Estriol sensitizes rat Kupffer cells via gut-derived endotoxin American Journal of Physiology - Gastrointestinal and Liver Physiology. 277. PMID 10484393 DOI: 10.1152/Ajpgi.1999.277.3.G671 |
0.331 |
|
| 1999 |
Bradham CA, Schemmer P, Stachlewitz RF, Thurman RG, Brenner DA. Activation of nuclear factor-kappaB during orthotopic liver transplantation in rats is protective and does not require Kupffer cells. Liver Transplantation and Surgery : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. 5: 282-93. PMID 10388501 DOI: 10.1002/Lt.500050401 |
0.423 |
|
| 1999 |
Enomoto N, Yamashina S, Kono H, Schemmer P, Rivera CA, Enomoto A, Nishiura T, Nishimura T, Brenner DA, Thurman RG. Development of a new, simple rat model of early alcohol-induced liver injury based on sensitization of Kupffer cells Hepatology. 29: 1680-1689. PMID 10347108 DOI: 10.1002/Hep.510290633 |
0.303 |
|
| 1999 |
Magness ST, Brenner DA. Targeted disruption of the mouse ferrochelatase gene producing an exon 10 deletion Biochimica Et Biophysica Acta. 1453: 161-174. PMID 9989256 DOI: 10.1016/S0925-4439(98)00096-9 |
0.301 |
|
| 1999 |
Hellerbrand C, Stefanovic B, Giordano F, Burchardt ER, Brenner DA. The role of TGFβ1 in initiating hepatic stellate cell activation in vivo Journal of Hepatology. 30: 77-87. PMID 9927153 DOI: 10.1016/S0168-8278(99)80010-5 |
0.397 |
|
| 1998 |
Bradham CA, Plümpe J, Manns MP, Brenner DA, Trautwein C. I. TNF-induced liver injury. American Journal of Physiology. Gastrointestinal and Liver Physiology. 275: G387-G392. PMID 29585442 DOI: 10.1152/Ajpgi.1998.275.3.G387 |
0.416 |
|
| 1998 |
Ikejima K, Enomoto N, Iimuro Y, Ikejima A, Fang D, Xu J, Forman DT, Brenner DA, Thurman RG. Estrogen increases sensitivity of hepatic Kupffer cells to endotoxin. American Journal of Physiology. Gastrointestinal and Liver Physiology. 274: G669-G676. PMID 29585282 DOI: 10.1152/Ajpgi.1998.274.4.G669 |
0.347 |
|
| 1998 |
Thurman RG, Bradford BU, Iimuro Y, Knecht KT, Arteel GE, Yin M, Connor HD, Wall C, Raleigh JA, Frankenberg MV, Adachi Y, Forman DT, Brenner D, Kadiiska M, Mason RP. The role of gut-derived bacterial toxins and free radicals in alcohol-induced liver injury. Journal of Gastroenterology and Hepatology. 13: S39-S50. PMID 28976690 DOI: 10.1111/Jgh.1998.13.S1.39 |
0.433 |
|
| 1998 |
Brenner DA. Signal transduction during liver regeneration. Journal of Gastroenterology and Hepatology. 13. PMID 28976689 DOI: 10.1111/Jgh.1998.13.S1.93 |
0.428 |
|
| 1998 |
Scarlett YV, Brenner DA, Bloomer JR. Hepatic porphyrias. Clinics in Liver Disease. 2: 77-102, vi. PMID 15560047 DOI: 10.1016/s1089-3261(05)70365-2 |
0.54 |
|
| 1998 |
Jobin C, Hellerbrand C, Licato LL, Brenner DA, Sartor RB. Mediation by NF-κB of cytokine induced expression of intercellular adhesion molecule 1 (ICAM-1) in an intestinal epithelial cell line, a process blocked by proteasome inhibitors Gut. 42: 779-787. PMID 9691914 DOI: 10.1136/Gut.42.6.779 |
0.315 |
|
| 1998 |
Hellerbrand C, Jobin C, Licato LL, Sartor RB, Brenner DA. Cytokines induce NF-κB in activated but not in quiescent rat hepatic stellate cells American Journal of Physiology-Gastrointestinal and Liver Physiology. 275. PMID 9688654 DOI: 10.1152/Ajpgi.1998.275.2.G269 |
0.408 |
|
| 1998 |
Bloomer J, Bruzzone C, Zhu L, Scarlett Y, Magness S, Brenner D. Molecular defects in ferrochelatase in patients with protoporphyria requiring liver transplantation. The Journal of Clinical Investigation. 102: 107-14. PMID 9649563 DOI: 10.1172/Jci1347 |
0.629 |
|
| 1998 |
Trautwein C, Rakemann T, Brenner DA, Streetz K, Licato L, Manns MP, Tiegs G. Concanavalin A—induced liver cell damage: Activation of intracellular pathways triggered by tumor necrosis factor in mice Gastroenterology. 114: 1035-1045. PMID 9558294 DOI: 10.1016/S0016-5085(98)70324-5 |
0.369 |
|
| 1998 |
Iimuro Y, Nishiura T, Hellerbrand C, Behrns KE, Schoonhoven R, Grisham JW, Brenner DA. NFkappaB prevents apoptosis and liver dysfunction during liver regeneration. Journal of Clinical Investigation. 101: 802-811. PMID 9466975 DOI: 10.1172/Jci483 |
0.491 |
|
| 1998 |
Nishiura T, Nishimura T, deSerres S, Nakagawa T, Brenner DA, Meyer AA. Gene Expression, Cytokine and Enzyme Activation in the Liver after Burn Injury: 206. Journal of Burn Care & Rehabilitation. 19. DOI: 10.1097/00004630-199801001-00206 |
0.374 |
|
| 1998 |
Hellerbrand C, Jobin C, Licato LL, Sartor RB, Brenner DA. NFκB mediates LPS-induced expression of IL-6 and ICAM-1 in activated hepatic stellate cells, a process blocked by proteasome inhibitors Journal of Hepatology. 28: 49. DOI: 10.1016/S0168-8278(98)80398-X |
0.342 |
|
| 1998 |
Hellerbrand C, Jobin C, Limuro Y, Licato L, Sartor R, Brenner D. Inhibition of proinllammatory molecule expression by adenovirus-mediated expression of an NFkB super repressor in activated hepatic stellate cells Gastroenterology. 114. DOI: 10.1016/S0016-5085(98)85087-7 |
0.366 |
|
| 1997 |
Xu Y, Bradham C, Brenner DA, Czaja MJ. Hydrogen peroxide-induced liver cell necrosis is dependent on AP-1 activation. American Journal of Physiology. Gastrointestinal and Liver Physiology. 273: G795-G803. PMID 29585127 DOI: 10.1152/Ajpgi.1997.273.4.G795 |
0.36 |
|
| 1997 |
Stefanovic B, Hellerbrand C, Holcik M, Briendl M, Liebhaber SA, Brenner DA. Posttranscriptional regulation of collagen α1(I) mRNA in hepatic stellate cells Molecular and Cellular Biology. 17: 5201-5209. PMID 9271398 DOI: 10.1128/Mcb.17.9.5201 |
0.313 |
|
| 1997 |
Rhoads JM, Argenzio RA, Chen W, Rippe RA, Westwick JK, Cox AD, Berschneider HM, Brenner DA. L-glutamine stimulates intestinal cell proliferation and activates mitogen-activated protein kinases. The American Journal of Physiology. 272: G943-53. PMID 9176200 DOI: 10.1152/Ajpgi.1997.272.5.G943 |
0.312 |
|
| 1997 |
Bradham CA, Stachlewitz RF, Gao W, Qian T, Jayadev S, Jenkins G, Hannun Y, Lemasters JJ, Thurman RG, Brenner DA. Reperfusion after liver transplantation in rats differentially activates the mitogen-activated protein kinases. Hepatology (Baltimore, Md.). 25: 1128-35. PMID 9141429 DOI: 10.1002/Hep.510250514 |
0.413 |
|
| 1996 |
Westwick JK, Fleckenstein J, Yin M, Yang SQ, Bradham CA, Brenner DA, Diehl AM. Differential regulation of hepatocyte DNA synthesis by cAMP in vitro in vivo American Journal of Physiology-Gastrointestinal and Liver Physiology. 271. PMID 8944691 DOI: 10.1152/Ajpgi.1996.271.5.G780 |
0.351 |
|
| 1996 |
Hellerbrand C, Wang SC, Tsukamoto H, Brenner DA, Rippe RA. Expression of intracellular adhesion molecule 1 by activated hepatic stellate cells. Hepatology. 24: 670-676. PMID 8781341 DOI: 10.1002/Hep.510240333 |
0.431 |
|
| 1995 |
Westwick JK, Weitzel C, Leffert HL, Brenner DA. Activation of Jun kinase is an early event in hepatic regeneration. Journal of Clinical Investigation. 95: 803-810. PMID 7860764 DOI: 10.1172/Jci117730 |
0.338 |
|
| 1995 |
Rippe RA, Almounajed G, Brenner DA. Sp1 binding activity increases in activated Ito cells Hepatology. 22: 241-251. DOI: 10.1002/Hep.1840220135 |
0.341 |
|
| 1994 |
Diehl AM, Yin M, Fleckenstein J, Yang SQ, Lin HZ, Brenner DA, Westwick J, Bagby G, Nelson S. Tumor necrosis factor-alpha induces c-jun during the regenerative response to liver injury American Journal of Physiology-Gastrointestinal and Liver Physiology. 267. PMID 7943321 DOI: 10.1152/Ajpgi.1994.267.4.G552 |
0.314 |
|
| 1993 |
Brenner DA, Westwick J, Breindl M. Type I collagen gene regulation and the molecular pathogenesis of cirrhosis. American Journal of Physiology-Gastrointestinal and Liver Physiology. 264. PMID 8476045 DOI: 10.1152/Ajpgi.1993.264.4.G589 |
0.304 |
|
| 1993 |
Hattori M, Tugores A, Westwick JK, Veloz L, Leffert HL, Karin M, Brenner DA. Activation of activating protein 1 during hepatic acute phase response. The American Journal of Physiology. 264: G95-103. PMID 8430810 DOI: 10.1152/Ajpgi.1993.264.1.G95 |
0.352 |
|
| 1992 |
Koch KS, Lu XP, Brenner DA, Leffert HL. Differential expression of the transfected liver-specific α1-inhibitor III gene in normal hepatocytes and hepatoma cells in culture Biochemical and Biophysical Research Communications. 183: 184-192. PMID 1543489 DOI: 10.1016/0006-291X(92)91626-2 |
0.338 |
|
| 1991 |
Hattori M, Tugores A, Veloz L, Karin M, Brenner DA. A simplified method for the preparation of transcriptionally active liver nuclear extracts. Dna and Cell Biology. 9: 777-81. PMID 2264931 DOI: 10.1089/Dna.1990.9.777 |
0.389 |
|
| 1990 |
Brenner DA, Buck M, Feitelberg SP, Chojkier M. Tumor necrosis factor-alpha inhibits albumin gene expression in a murine model of cachexia. Journal of Clinical Investigation. 85: 248-255. PMID 2295699 DOI: 10.1172/Jci114419 |
0.313 |
|
| 1990 |
Brenner DA, Alcorn JM. Therapy for hepatic fibrosis. Seminars in Liver Disease. 10: 75-83. PMID 2186490 DOI: 10.1055/S-2008-1040459 |
0.335 |
|
| 1990 |
Alcorn JA, Feitelberg SP, Brenner DA. Transient induction of C‐jun during hepatic regeneration Hepatology. 11: 909-915. PMID 2114348 DOI: 10.1002/Hep.1840110602 |
0.36 |
|
| 1990 |
Rippe RA, Brenner DA, Leffert HL. DNA-mediated gene transfer into adult rat hepatocytes in primary culture. Molecular and Cellular Biology. 10: 689-695. PMID 2105458 DOI: 10.1128/Mcb.10.2.689 |
0.318 |
|
| 1988 |
Chojkier M, Brenner DA. Therapeutic strategies for hepatic fibrosis Hepatology. 8: 176-182. PMID 3276587 DOI: 10.1002/Hep.1840080132 |
0.403 |
|
| 1986 |
Brenner DA, Smigocki AC, Camerini-Otero RD. Double-strand gap repair results in homologous recombination in mouse L cells. Proceedings of the National Academy of Sciences of the United States of America. 83: 1762-6. PMID 3006069 DOI: 10.1073/pnas.83.6.1762 |
0.492 |
|
| 1985 |
Brenner DA, Smigocki AC, Camerini-Otero RD. Effect of insertions, deletions, and double-strand breaks on homologous recombination in mouse L cells. Molecular and Cellular Biology. 5: 684-91. PMID 3990689 DOI: 10.1128/mcb.5.4.684 |
0.497 |
|
| 1984 |
Brenner DA, Kato S, Anderson RA, Smigocki AC, Camerini-Otero RD. The recombination and integration of DNAs introduced into mouse L cells. Cold Spring Harbor Symposia On Quantitative Biology. 49: 151-60. PMID 6597753 DOI: 10.1101/sqb.1984.049.01.018 |
0.487 |
|
| 1980 |
Brenner DA, Bloomer JR. The enzymatic defect in variegate prophyria. Studies with human cultured skin fibroblasts. The New England Journal of Medicine. 302: 765-9. PMID 7354807 DOI: 10.1056/Nejm198004033021401 |
0.554 |
|
| 1980 |
Brenner DA, Bloomer JR. A fluorometric assay for measurement of protoporphyrinogen oxidase activity in mammalian tissue. Clinica Chimica Acta; International Journal of Clinical Chemistry. 100: 259-66. PMID 7353311 DOI: 10.1016/0009-8981(80)90275-2 |
0.567 |
|
| 1979 |
Brenner DA, Bloomer JR. Comparison of human and bovine protoporphyria. The Yale Journal of Biology and Medicine. 52: 449-54. PMID 392959 |
0.481 |
|
| 1977 |
Bloomer JR, Brenner DA, Mahoney MJ. Study of factors causing excess protoporphyrin accumulation in cultured skin fibroblasts from patients with protoporphyria. The Journal of Clinical Investigation. 60: 1354-61. PMID 915001 DOI: 10.1172/JCI108895 |
0.477 |
|
| 1977 |
Brenner DA, Bloomer JR. Heme content of normal and porphyric cultured skin fibroblasts. Biochemical Genetics. 15: 1061-70. PMID 603614 DOI: 10.1007/Bf00484497 |
0.534 |
|
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