Chris C. Ashley, BSc, PhD - Publications

Affiliations: 
Physiology University of Oxford, Oxford, United Kingdom 

77 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Ashley CC. Professor Andrew Fielding Huxley, OM, FRS, 1917-2012. Journal of Muscle Research and Cell Motility. 33: 291. PMID 22941181 DOI: 10.1007/s10974-012-9321-x  1
2009 Griffiths PJ, Isackson H, Pelc R, Redwood CS, Funari SS, Watkins H, Ashley CC. Synchronous in situ ATPase activity, mechanics, and Ca2+ sensitivity of human and porcine myocardium. Biophysical Journal. 97: 2503-12. PMID 19883593 DOI: 10.1016/j.bpj.2009.07.058  1
2009 Pelc R, Ishii N, Ashley CC. Laser flash photolysis of diazo-2, a caged calcium chelator: The relationship between the extent and rate of smooth muscle relaxation Journal of Laser Applications. 21: 32-38. DOI: 10.2351/1.3071377  1
2007 Robinson P, Lipscomb S, Preston LC, Altin E, Watkins H, Ashley CC, Redwood CS. Mutations in fast skeletal troponin I, troponin T, and beta-tropomyosin that cause distal arthrogryposis all increase contractile function. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 896-905. PMID 17194691 DOI: 10.1096/fj.06-6899com  1
2007 Preston LC, Lipscomb S, Robinson P, Mogensen J, McKenna WJ, Watkins H, Ashley CC, Redwood CS. Functional effects of the DCM mutant Gly159Asp troponin C in skinned muscle fibres. PflüGers Archiv : European Journal of Physiology. 453: 771-6. PMID 17021793 DOI: 10.1007/s00424-006-0161-7  1
2006 Griffiths PJ, Bagni MA, Colombini B, Amenitsch H, Bernstorff S, Funari S, Ashley CC, Cecchi G. Effects of the number of actin-bound S1 and axial force on X-ray patterns of intact skeletal muscle. Biophysical Journal. 90: 975-84. PMID 16272435 DOI: 10.1529/biophysj.105.068619  1
2005 Griffiths PJ, Bagni MA, Colombini B, Amenitsch H, Bernstorff S, Ashley CC, Cecchi G. Myosin lever disposition during length oscillations when power stroke tilting is reduced. American Journal of Physiology. Cell Physiology. 289: C177-86. PMID 15743885 DOI: 10.1152/ajpcell.00020.2005  1
2005 Lipscomb S, Preston LC, Robinson P, Redwood CS, Mulligan IP, Ashley CC. Effects of troponin C isoform on the action of the cardiotonic agent EMD 57033. The Biochemical Journal. 388: 905-12. PMID 15705058 DOI: 10.1042/BJ20041841  1
2003 Cecchi G, Bagni MA, Colombini B, Ashley CC, Amenitsch H, Bernstorff S, Griffiths PJ. Use of sinusoidal length oscillations to detect myosin conformation by time-resolved X-ray diffraction. Advances in Experimental Medicine and Biology. 538: 267-77; discussion 2. PMID 15098674  1
2002 Griffiths PJ, Bagni MA, Colombini B, Amenitsch H, Bernstorff S, Ashley CC, Cecchi G, Ameritsch H. Changes in myosin S1 orientation and force induced by a temperature increase. Proceedings of the National Academy of Sciences of the United States of America. 99: 5384-9. PMID 11959993 DOI: 10.1073/pnas.082482599  1
2001 Bagni MA, Colombini B, Amenitsch H, Bernstorff S, Ashley CC, Rapp G, Griffiths PJ. Frequency-dependent distortion of meridional intensity changes during sinusoidal length oscillations of activated skeletal muscle. Biophysical Journal. 80: 2809-22. PMID 11371455 DOI: 10.1016/S0006-3495(01)76248-0  1
2001 Hoskins BK, Ashley CC, Rapp G, Griffiths PJ. Time-resolved X-ray diffraction by skinned skeletal muscle fibers during activation and shortening. Biophysical Journal. 80: 398-414. PMID 11159411 DOI: 10.1016/S0006-3495(01)76023-7  1
2000 Allhouse LD, Li Q, Guzman G, Miller T, Lipscomb S, Potter JD, Ashley CC. Investigating the role of Ca2+-binding site IV in barnacle troponin C. PflüGers Archiv : European Journal of Physiology. 439: 600-9. PMID 10764220  1
1999 Johns EC, Ryder KO, Hodson EA, Hart G, Mulligan IP, Lipscomb S, Ashley CC. Investigating the relaxation rate, following diazo-2 photolysis, of a skinned trabecular preparation from guinea-pig hypertrophied left ventricle. PflüGers Archiv : European Journal of Physiology. 438: 771-7. PMID 10591064 DOI: 10.1007/s004240051105  1
1999 Hoskins BK, Ashley CC, Pelc R, Rapp G, Griffiths PJ. Time-resolved equatorial X-ray diffraction studies of skinned muscle fibres during stretch and release. Journal of Molecular Biology. 290: 77-97. PMID 10388559 DOI: 10.1006/jmbi.1999.2857  1
1999 Allhouse LD, Potter JD, Ashley CC. A novel method of extraction of TnC from skeletal muscle myofibrils. PflüGers Archiv : European Journal of Physiology. 437: 695-701. PMID 10087146 DOI: 10.1007/s004240050834  1
1999 Lipscomb S, Palmer RE, Li Q, Allhouse LD, Miller T, Potter JD, Ashley CC. A diazo-2 study of relaxation mechanisms in frog and barnacle muscle fibres: effects of pH, MgADP, and inorganic phosphate. PflüGers Archiv : European Journal of Physiology. 437: 204-12. PMID 9929560 DOI: 10.1007/s004240050770  1
1999 Hoskins BK, Lipscomb S, Mulligan IP, Ashley CC. How do skinned skeletal muscle fibers relax? Biochemical and Biophysical Research Communications. 254: 330-3. PMID 9918838 DOI: 10.1006/bbrc.1998.9879  1
1999 Mulligan IP, Palmer RE, Lipscomb S, Hoskins B, Ashley CC. The effect of phosphate on the relaxation of frog skeletal muscle. PflüGers Archiv : European Journal of Physiology. 437: 393-9. PMID 9914395 DOI: 10.1007/s004240050793  1
1999 Ashley CC, Bagni MA, Cecchi G, Griffiths PJ, Rapp G. Submillisecond changes in myosin lattice spacing resulting from rapid length changes. Journal of Molecular Biology. 285: 431-40. PMID 9878417 DOI: 10.1006/jmbi.1998.2331  1
1998 Griffiths PJ, Amenitsch H, Ashley CC, Bagni MA, Bernstorff S, Cecchi G, Colombini B, Rapp G. Studies on the 14.5 nm meridional X-ray diffraction reflection during length changes of intact frog muscle fibres. Advances in Experimental Medicine and Biology. 453: 247-57; discussion 2. PMID 9889836  1
1998 Rapp G, Ashley CC, Bagni MA, Griffiths PJ, Cecchi G. Volume changes of the myosin lattice resulting from repetitive stimulation of single muscle fibers. Biophysical Journal. 75: 2984-95. PMID 9826618 DOI: 10.1016/S0006-3495(98)77739-2  1
1998 Simnett SJ, Johns EC, Lipscomb S, Mulligan IP, Ashley CC. Effect of pH, phosphate, and ADP on relaxation of myocardium after photolysis of diazo 2. The American Journal of Physiology. 275: H951-60. PMID 9724300  1
1998 Du GG, Ashley CC, Lea TJ. The cation selectivity of the sarcoball Ca2+ channel in frog muscle fibres. PflüGers Archiv : European Journal of Physiology. 436: 365-70. PMID 9644217  0.76
1997 Pelc R, Ashley CC. Capillary force-driven cell perfusion microchamber: calcium transients in isolated smooth muscle cells. PflüGers Archiv : European Journal of Physiology. 435: 174-7. PMID 9359917 DOI: 10.1007/s004240050497  1
1996 Du GG, Ashley CC, Lea TJ. Ca2+ effluxes from the sarcoplasmic reticulum vesicles of frog muscle: effects of cyclopiazonic acid and thapsigargin. Cell Calcium. 20: 355-9. PMID 8939355  0.76
1996 Du GG, Ashley CC, Lea TJ. Effects of thapsigargin and cyclopiazonic acid on sarcoplasmic reticulum Ca2+ uptake, spontaneous force oscillations and myofilament Ca2+ sensitivity in skinned rat ventricular trabeculae. PflüGers Archiv : European Journal of Physiology. 432: 59-65. PMID 8662268  0.76
1994 Simnett SJ, Lipscomb S, Ashley CC, Potter JD, Mulligan IP. The thiadiazinone EMD 57033 speeds the activation of skinned cardiac muscle produced by the photolysis of nitr-5. PflüGers Archiv : European Journal of Physiology. 427: 550-2. PMID 7971154 DOI: 10.1007/BF00374274  1
1994 Du GG, Ashley CC, Lea TJ. Effects of thapsigargin and cyclopiazonic acid on the sarcoplasmic reticulum Ca2+ pump of skinned fibres from frog skeletal muscle. PflüGers Archiv : European Journal of Physiology. 429: 169-75. PMID 7892102  0.76
1994 Bagni MA, Cecchi G, Griffiths PJ, Maéda Y, Rapp G, Ashley CC. Lattice spacing changes accompanying isometric tension development in intact single muscle fibers. Biophysical Journal. 67: 1965-75. PMID 7858133 DOI: 10.1016/S0006-3495(94)80679-4  1
1993 Griffiths PJ, Ashley CC, Bagni MA, Maéda Y, Cecchi G. Cross-bridge attachment and stiffness during isotonic shortening of intact single muscle fibers. Biophysical Journal. 64: 1150-60. PMID 8494976 DOI: 10.1016/S0006-3495(93)81481-4  1
1993 Simnett SJ, Lipscomb S, Ashley CC, Mulligan IP. The effect of EMD 57033, a novel cardiotonic agent, on the relaxation of skinned cardiac and skeletal muscle produced by photolysis of diazo-2, a caged calcium chelator. PflüGers Archiv : European Journal of Physiology. 425: 175-7. PMID 8272375 DOI: 10.1007/BF00374519  1
1993 Ashley CC, Griffiths PJ, Lea TJ, Mulligan IP, Palmer RE, Simnett SJ. Barnacle muscle: Ca2+, activation and mechanics. Reviews of Physiology, Biochemistry and Pharmacology. 122: 149-258. PMID 8265964  1
1993 Ashley CC, Lea TJ, Mulligan IP, Palmer RE, Simnett SJ. Activation and relaxation mechanisms in single muscle fibres. Advances in Experimental Medicine and Biology. 332: 97-114; discussion 1. PMID 8109389  0.76
1993 Griffiths PJ, Ashley CC, Bagni MA, Cecchi G, Maèda Y. Time-resolved equatorial X-ray diffraction measurements in single intact muscle fibres. Advances in Experimental Medicine and Biology. 332: 409-20; discussion 4. PMID 8109354  1
1992 Lea TJ, Ashley CC. Ca-induced Ca release from the SR of barnacle myofibrillar bundles, triggered by the photorelease of calcium ions from caged calcium. Advances in Experimental Medicine and Biology. 311: 433-4. PMID 1529785  1
1991 Supattapone S, Ashley CC. Endothelin Opens Potassium Channels in Glial Cells. The European Journal of Neuroscience. 3: 349-355. PMID 12106193  1
1991 Ashley CC, Mulligan IP, Lea TJ. Ca2+ and activation mechanisms in skeletal muscle. Quarterly Reviews of Biophysics. 24: 1-73. PMID 2047521  0.76
1991 Cecchi G, Griffiths PJ, Bagni MA, Ashley CC, Maeda Y. Time-resolved changes in equatorial x-ray diffraction and stiffness during rise of tetanic tension in intact length-clamped single muscle fibers. Biophysical Journal. 59: 1273-83. PMID 1873464 DOI: 10.1016/S0006-3495(91)82342-6  1
1991 Ashley CC, Lea TJ, Hoar PE, Kerrick WG, Strang PF, Potter JD. Functional characterization of the two isoforms of troponin C from the arthropod Balanus nubilus. Journal of Muscle Research and Cell Motility. 12: 532-42. PMID 1791193  0.76
1991 Supattapone S, Ashley CC. Endothelin increases rubidium uptake through calcium-activated potassium channels in C6 glioma cells. Annals of the New York Academy of Sciences. 633: 597-8. PMID 1789589  1
1990 Palmer RE, Mulligan IP, Nunn C, Ashley CC. Striated scallop muscle relaxation: fast force transients produced by photolysis of Diazo-2. Biochemical and Biophysical Research Communications. 168: 295-300. PMID 2328006 DOI: 10.1016/0006-291X(90)91707-Y  1
1990 Cecchi G, Bagni MA, Griffiths PJ, Ashley CC, Maeda Y. Detection of radial crossbridge force by lattice spacing changes in intact single muscle fibers. Science (New York, N.Y.). 250: 1409-11. PMID 2255911  1
1990 Simpson AW, Ashley CC. Endothelin and vasopressin evoked elevation of intracellular free Ca2+ ([Ca2+]i) in A10 rat aortic smooth muscle cells. Progress in Clinical and Biological Research. 327: 559-63. PMID 2181475  1
1990 Griffiths PJ, Duchateau JJ, Maeda Y, Potter JD, Ashley CC. Mechanical characteristics of skinned and intact muscle fibres from the giant barnacle, Balanus nubilus. PflüGers Archiv : European Journal of Physiology. 415: 554-65. PMID 2139207 DOI: 10.1007/BF02583506  1
1990 Lea TJ, Ashley CC. Ca2+ release from the sarcoplasmic reticulum of barnacle myofibrillar bundles initiated by photolysis of caged Ca2+. The Journal of Physiology. 427: 435-53. PMID 2120428  1
1990 Lea TJ, Fenton MJ, Potter JD, Ashley CC. Rapid activation by photolysis of nitr-5 in skinned fibres of the striated adductor muscle from the scallop. Biochimica Et Biophysica Acta. 1034: 186-94. PMID 2112954  0.76
1989 Lea TJ, Ashley CC. Ca-induced Ca release from the sarcoplasmic reticulum of isolated myofibrillar bundles of barnacle muscle fibres. PflüGers Archiv : European Journal of Physiology. 413: 401-6. PMID 2928093 DOI: 10.1007/BF00584490  1
1989 Mulligan IP, Ashley CC. Rapid relaxation of single frog skeletal muscle fibres following laser flash photolysis of the caged calcium chelator, diazo-2. Febs Letters. 255: 196-200. PMID 2507351 DOI: 10.1016/0014-5793(89)81090-7  1
1989 Simpson AW, Ashley CC. Endothelin evoked Ca2+ transients and oscillations in A10 vascular smooth muscle cells. Biochemical and Biophysical Research Communications. 163: 1223-9. PMID 2506860 DOI: 10.1016/0006-291X(89)91108-X  1
1989 Simpson AW, Ashley CC. Spontaneous oscillations and agonist-evoked changes in Ca2+ in cultured smooth muscle cells. Journal of Cardiovascular Pharmacology. 14: S59-62. PMID 2478826  1
1988 Griffiths PJ, Potter JD, Maéda Y, Ashley CC. Transient kinetics and time-resolved X-ray diffraction studies in isolated single muscle fibres. Advances in Experimental Medicine and Biology. 226: 113-28. PMID 3407511  1
1987 Pritchard K, Ashley CC. Evidence for Na+/Ca2+ exchange in isolated smooth muscle cells: a fura-2 study. PflüGers Archiv : European Journal of Physiology. 410: 401-7. PMID 3432047 DOI: 10.1007/BF00586517  1
1987 Jackson AP, Timmerman MP, Bagshaw CR, Ashley CC. The kinetics of calcium binding to fura-2 and indo-1. Febs Letters. 216: 35-9. PMID 3108033 DOI: 10.1016/0014-5793(87)80752-4  1
1986 Timmerman MP, Ashley CC. Fura-2 diffusion and its use as an indicator of transient free calcium changes in single striated muscle cells. Febs Letters. 209: 1-8. PMID 3803567 DOI: 10.1016/0014-5793(86)81073-0  1
1986 Pritchard K, Ashley CC. Na+/Ca2+ exchange in isolated smooth muscle cells demonstrated by the fluorescent calcium indicator fura-2. Febs Letters. 195: 23-7. PMID 3753685 DOI: 10.1016/0014-5793(86)80122-3  1
1986 Lea TJ, Griffiths PJ, Tregear RT, Ashley CC. An examination of the ability ofinositol 1,4,5-trisphosphate to induce calcium release and tension development in skinned skeletal muscle fibres of frog and crustacea Febs Letters. 207: 153-161. PMID 3490400 DOI: 10.1016/0014-5793(86)80031-X  1
1985 Ashley CC, Potter JD, Strang P, Godber J, Walton A, Griffiths PJ. Kinetic investigations in single muscle fibres using luminescent and fluorescent Ca2+ probes. Cell Calcium. 6: 159-81. PMID 3893726 DOI: 10.1016/0143-4160(85)90042-9  1
1984 Griffiths PJ, Potter JD, Coles B, Strang P, Ashley CC. Fluorescence changes from single striated muscle fibres injected with labelled troponin C (TnCDANZ). Febs Letters. 176: 144-50. PMID 6489515 DOI: 10.1016/0014-5793(84)80929-1  1
1982 Williamson RE, Ashley CC. Free Ca2+ and cytoplasmic streaming in the alga Chara. Nature. 296: 647-50. PMID 7070508 DOI: 10.1038/296647a0  1
1982 Lea TJ, Ashley CC. The effect of pH on the rate of relaxation of isolated barnacle myofibrillar bundles. Biochimica Et Biophysica Acta. 681: 130-7. PMID 6810930 DOI: 10.1016/0005-2728(82)90286-9  1
1981 Lea TJ, Ashley CC. Harmaline distribution in single muscle fibres and the inhibition of sodium efflux. Biochimica Et Biophysica Acta. 644: 74-81. PMID 7260069 DOI: 10.1016/0005-2736(81)90060-2  1
1981 Lea TJ, Ashley CC. Carbon dioxide or bicarbonate ions release Ca2+ from internal stores in crustacean myofibrillar bundles. The Journal of Membrane Biology. 61: 115-25. PMID 6456353 DOI: 10.1007/BF02007638  1
1979 Ashley CC, Franciolini F, Lea TJ, Lignon J. Effect of carbon dioxide on calcium transient and tension responses from fibres of the barnacle Balanus nubilus [proceedings]. The Journal of Physiology. 296: 71P. PMID 43393  0.76
1978 Ashley CC, Ellory JC, Lea TJ, Ramos M. The effects of inhibitors on 36Cl efflux from barnacle muscle fibres [proceedings]. The Journal of Physiology. 285: 52P-53P. PMID 745120  0.76
1978 Ashley CC, Campbell AK. Free-calcium and tension responses in single barnacle muscle fibres following the application of L-glutamate. Biochimica Et Biophysica Acta. 512: 429-35. PMID 708728 DOI: 10.1016/0005-2736(78)90265-1  1
1978 Ashley CC, Rink TJ, Tsien RY. Changes in free Ca during muscle contraction, measured with an intracellular Ca-selective electrode [proceedings]. The Journal of Physiology. 280: 27P. PMID 690875  1
1978 Ashley CC, Lea TJ. Calcium fluxes in single muscle fibres measured with a glass scintillator probe. The Journal of Physiology. 282: 307-31. PMID 102762  1
1978 Ashley CC, Lea TJ. Intracellular free Ca increased by lowering pH [proceedings]. The Journal of Physiology. 282: 21P-22P. PMID 31460  1
1978 Ashley CC. Calcium ion regulation in barnacle muscle fibers and its relation to force development. Annals of the New York Academy of Sciences. 307: 308-29. PMID 30379  1
1978 Lea TJ, Ashley CC. Increase in free Ca2+ in muscle after exposure to CO2. Nature. 275: 236-8. PMID 29230 DOI: 10.1038/275236a0  1
1977 Ashley CC, Ellory JC, Griffiths PJ. Caffeine and the contractility of single muscle fibres from the barnacle Balanus nubilus. The Journal of Physiology. 269: 421-39. PMID 894601  1
1977 Ashley CC, Moisescu DG. Effect of changing the composition of the bathing solutions upon the isometric tension-pCa relationship in bundles of crustacean myofibrils. The Journal of Physiology. 270: 627-52. PMID 20499  1
1977 Moisescu DG, Ashley CC. The effect of physiologically occurring cations upon aequorin light emission. Determination of the binding constants. Biochimica Et Biophysica Acta. 460: 189-205. PMID 15592 DOI: 10.1016/0005-2728(77)90206-7  1
1975 Ashley CC, Caldwell PC, Lea TJ. Proceedings: Calcium influx into single crustacean muscle fibres as measured with a glass scintillator probe Journal of Physiology. 248: 9P-10P. PMID 1151834  1
1974 Ashley CC, Caldwell PC. Calcium movements in relation to contraction Biochemical Society Symposia. 29-50. PMID 4220104  1
1972 Ashley CC, Caldwell PC, Lowe AG. The efflux of calcium from single crab and barnacle muscle fibres The Journal of Physiology. 223: 735-755. PMID 5045739 DOI: 10.1113/jphysiol.1972.sp009872  1
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