Christian Wolfrum - Publications

Affiliations: 
HEST Eidgenössische Technische Hochschule Zürich, Zürich, ZH, Switzerland 

94 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Reinisch I, Michenthaler H, Sulaj A, Moyschewitz E, Krstic J, Galhuber M, Xu R, Riahi Z, Wang T, Vujic N, Amor M, Zenezini Chiozzi R, Wabitsch M, Kolb D, Georgiadi A, ... ... Wolfrum C, et al. Adipocyte p53 coordinates the response to intermittent fasting by regulating adipose tissue immune cell landscape. Nature Communications. 15: 1391. PMID 38360943 DOI: 10.1038/s41467-024-45724-y  0.743
2024 Dewal RS, Yang FT, Baer LA, Vidal P, Hernandez-Saavedra D, Seculov NP, Ghosh A, Noé F, Togliatti O, Hughes L, DeBari MK, West MD, Soroko R, Sternberg H, Malik NN, ... ... Wolfrum C, et al. Transplantation of committed pre-adipocytes from brown adipose tissue improves whole-body glucose homeostasis. Iscience. 27: 108927. PMID 38327776 DOI: 10.1016/j.isci.2024.108927  0.415
2023 Hagemann T, Czechowski P, Ghosh A, Sun W, Dong H, Noé F, Wolfrum C, Blüher M, Hoffmann A. Laminin α4 Expression in Human Adipose Tissue Depots and Its Association with Obesity and Obesity Related Traits. Biomedicines. 11. PMID 37893179 DOI: 10.3390/biomedicines11102806  0.741
2023 Giroud M, Kotschi S, Kwon Y, Le Thuc O, Hoffmann A, Gil-Lozano M, Karbiener M, Higareda-Almaraz JC, Khani S, Tews D, Fischer-Posovszky P, Sun W, Dong H, Ghosh A, Wolfrum C, et al. The obesity-linked human lncRNA AATBC stimulates mitochondrial function in adipocytes. Embo Reports. e57600. PMID 37671834 DOI: 10.15252/embr.202357600  0.768
2023 Maushart CI, Sun W, Othman A, Ghosh A, Senn JR, Fischer JGW, Madoerin P, Loeliger RC, Benz RM, Takes M, Zech CJ, Chirindel A, Beuschlein F, Reincke M, Wild D, ... ... Wolfrum C, et al. Effect of high-dose glucocorticoid treatment on human brown adipose tissue activity: a randomised, double-blinded, placebo-controlled cross-over trial in healthy men. Ebiomedicine. 96: 104771. PMID 37659283 DOI: 10.1016/j.ebiom.2023.104771  0.724
2023 Efthymiou V, Ding L, Balaz M, Sun W, Balazova L, Straub LG, Dong H, Simon E, Ghosh A, Perdikari A, Keller S, Ghoshdastider U, Horvath C, Moser C, Hamilton B, ... ... Wolfrum C, et al. Inhibition of AXL receptor tyrosine kinase enhances brown adipose tissue functionality in mice. Nature Communications. 14: 4162. PMID 37443109 DOI: 10.1038/s41467-023-39715-8  0.755
2023 Dewal RS, Wolfrum C. Master of disguise: deconvoluting adipose tissue heterogeneity and its impact on metabolic health. Current Opinion in Genetics & Development. 81: 102085. PMID 37421902 DOI: 10.1016/j.gde.2023.102085  0.441
2023 Palani NP, Horvath C, Timshel PN, Folkertsma P, Grønning AGB, Henriksen TI, Peijs L, Jensen VH, Sun W, Jespersen NZ, Wolfrum C, Pers TH, Nielsen S, Scheele C. Adipogenic and SWAT cells separate from a common progenitor in human brown and white adipose depots. Nature Metabolism. 5: 996-1013. PMID 37337126 DOI: 10.1038/s42255-023-00820-z  0.726
2023 Steenblock C, Bechmann N, Beuschlein F, Wolfrum C, Bornstein SR. Do adipocytes serve as a reservoir for SARS-CoV-2? The Journal of Endocrinology. PMID 37227170 DOI: 10.1530/JOE-23-0027  0.43
2023 Schönauer R, Jin W, Findeisen C, Valenzuela I, Devlin LA, Murrell J, Bedoukian EC, Pöschla L, Hantmann E, Riedhammer KM, Hoefele J, Platzer K, Biemann R, Campeau PM, Münch J, ... ... Wolfrum C, et al. Monoallelic intragenic POU3F2 variants lead to neurodevelopmental delay and hyperphagic obesity, confirming the gene's candidacy in 6q16.1 deletions. American Journal of Human Genetics. PMID 37207645 DOI: 10.1016/j.ajhg.2023.04.010  0.704
2023 Meen AJ, Doncheva AI, Böttcher Y, Dankel SN, Hoffmann A, Blüher M, Fernø J, Mellgren G, Ghosh A, Sun W, Dong H, Noé F, Wolfrum C, Pejler G, Dalen KT, et al. Obesity Is Associated with Distorted Proteoglycan Expression in Adipose Tissue. International Journal of Molecular Sciences. 24. PMID 37108048 DOI: 10.3390/ijms24086884  0.771
2023 Rajcsanyi LS, Hoffmann A, Ghosh A, Matrisch-Dinkler B, Zheng Y, Peters T, Sun W, Dong H, Noé F, Wolfrum C, Herpertz-Dahlmann B, Seitz J, de Zwaan M, Herzog W, Ehrlich S, et al. Genetic variants in genes involved in creatine biosynthesis in patients with severe obesity or anorexia nervosa. Frontiers in Genetics. 14: 1128133. PMID 37101650 DOI: 10.3389/fgene.2023.1128133  0.73
2023 Long F, Bhatti MR, Kellenberger A, Sun W, Modica S, Höring M, Liebisch G, Krieger JP, Wolfrum C, Challa TD. A low-carbohydrate diet induces hepatic insulin resistance and metabolic associated fatty liver disease in mice. Molecular Metabolism. 69: 101675. PMID 36682412 DOI: 10.1016/j.molmet.2023.101675  0.67
2022 Christen L, Broghammer H, Rapöhn I, Möhlis K, Strehlau C, Ribas-Latre A, Gebhardt C, Roth L, Krause K, Landgraf K, Körner A, Rohde-Zimmermann K, Hoffmann A, Klöting N, Ghosh A, ... ... Wolfrum C, et al. Myoglobin-mediated lipid shuttling increases adrenergic activation of brown and white adipocyte metabolism and is as a marker of thermogenic adipocytes in humans. Clinical and Translational Medicine. 12: e1108. PMID 36480426 DOI: 10.1002/ctm2.1108  0.719
2022 Hoces D, Lan J, Sun W, Geiser T, Stäubli ML, Cappio Barazzone E, Arnoldini M, Challa TD, Klug M, Kellenberger A, Nowok S, Faccin E, Macpherson AJ, Stecher B, Sunagawa S, ... ... Wolfrum C, et al. Metabolic reconstitution of germ-free mice by a gnotobiotic microbiota varies over the circadian cycle. Plos Biology. 20: e3001743. PMID 36126044 DOI: 10.1371/journal.pbio.3001743  0.688
2022 Gonzalez-Franquesa A, Gama-Perez P, Kulis M, Szczepanowska K, Dahdah N, Moreno-Gomez S, Latorre-Pellicer A, Fernández-Ruiz R, Aguilar-Mogas A, Hoffman A, Monelli E, Samino S, Miró-Blanch J, Oemer G, Duran X, ... ... Wolfrum C, et al. Remission of obesity and insulin resistance is not sufficient to restore mitochondrial homeostasis in visceral adipose tissue. Redox Biology. 54: 102353. PMID 35777200 DOI: 10.1016/j.redox.2022.102353  0.775
2022 Wolfrum C, Gerhart-Hines Z. Fueling the fire of adipose thermogenesis. Science (New York, N.Y.). 375: 1229-1231. PMID 35298244 DOI: 10.1126/science.abl7108  0.343
2022 Dong H, Sun W, Shen Y, Baláz M, Balázová L, Ding L, Löffler M, Hamilton B, Klöting N, Blüher M, Neubauer H, Klein H, Wolfrum C. Identification of a regulatory pathway inhibiting adipogenesis via RSPO2. Nature Metabolism. PMID 35027768 DOI: 10.1038/s42255-021-00509-1  0.771
2021 Wang T, Sharma AK, Wolfrum C. Novel insights into adipose tissue heterogeneity. Reviews in Endocrine & Metabolic Disorders. PMID 34935088 DOI: 10.1007/s11154-021-09703-8  0.434
2021 Ding L, Sun W, Balaz M, He A, Klug M, Wieland S, Caiazzo R, Raverdy V, Pattou F, Lefebvre P, Lodhi IJ, Staels B, Heim M, Wolfrum C. Peroxisomal β-oxidation acts as a sensor for intracellular fatty acids and regulates lipolysis. Nature Metabolism. PMID 34903883 DOI: 10.1038/s42255-021-00489-2  0.673
2021 Balazova L, Balaz M, Horvath C, Horváth Á, Moser C, Kovanicova Z, Ghosh A, Ghoshdastider U, Efthymiou V, Kiehlmann E, Sun W, Dong H, Ding L, Amri EZ, Nuutila P, ... ... Wolfrum C, et al. GPR180 is a component of TGFβ signalling that promotes thermogenic adipocyte function and mediates the metabolic effects of the adipocyte-secreted factor CTHRC1. Nature Communications. 12: 7144. PMID 34880217 DOI: 10.1038/s41467-021-27442-x  0.696
2021 Felder M, Maushart CI, Gashi G, Senn JR, Becker AS, Müller J, Balaz M, Wolfrum C, Burger IA, Betz MJ. Fluvastatin Reduces Glucose Tolerance in Healthy Young Individuals Independently of Cold Induced BAT Activity. Frontiers in Endocrinology. 12: 765807. PMID 34858338 DOI: 10.3389/fendo.2021.765807  0.335
2021 Sun W, Dong H, Wolfrum C. Local acetate inhibits brown adipose tissue function. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34845033 DOI: 10.1073/pnas.2116125118  0.752
2021 Schmidt V, Horváth C, Dong H, Blüher M, Qvist P, Wolfrum C, Willnow TE. SORLA is required for insulin-induced expansion of the adipocyte precursor pool in visceral fat. The Journal of Cell Biology. 220. PMID 34779857 DOI: 10.1083/jcb.202006058  0.441
2021 Li M, Li L, Li B, Hambly C, Wang G, Wu Y, Jin Z, Wang A, Niu C, Wolfrum C, Speakman JR. Brown adipose tissue is the key depot for glucose clearance in microbiota depleted mice. Nature Communications. 12: 4725. PMID 34354051 DOI: 10.1038/s41467-021-24659-8  0.317
2021 Sun W, Modica S, Dong H, Wolfrum C. Plasticity and heterogeneity of thermogenic adipose tissue. Nature Metabolism. 3: 751-761. PMID 34158657 DOI: 10.1038/s42255-021-00417-4  0.748
2021 Moser C, Straub LG, Rachamin Y, Dapito DH, Kulenkampff E, Ding L, Sun W, Modica S, Balaz M, Wolfrum C. Quantification of adipocyte numbers following adipose tissue remodeling. Cell Reports. 35: 109023. PMID 33909996 DOI: 10.1016/j.celrep.2021.109023  0.736
2021 Lee JH, Lin L, Ye X, Wolfrum C, Chen Y, Guo S, Sun Y. GHS-R in brown fat potentiates differential thermogenic responses under metabolic and thermal stresses. Plos One. 16: e0249420. PMID 33793646 DOI: 10.1371/journal.pone.0249420  0.386
2020 Sun W, Dong H, Balaz M, Slyper M, Drokhlyansky E, Colleluori G, Giordano A, Kovanicova Z, Stefanicka P, Balazova L, Ding L, Husted AS, Rudofsky G, Ukropec J, Cinti S, ... ... Wolfrum C, et al. snRNA-seq reveals a subpopulation of adipocytes that regulates thermogenesis. Nature. PMID 33116305 DOI: 10.1038/s41586-020-2856-x  0.785
2020 Müller S, Perdikari A, Dapito DH, Sun W, Wollscheid B, Balaz M, Wolfrum C. ESRRG and PERM1 Govern Mitochondrial Conversion in Brite/Beige Adipocyte Formation. Frontiers in Endocrinology. 11: 387. PMID 32595605 DOI: 10.3389/fendo.2020.00387  0.729
2020 Horvath C, Wolfrum C. Feeding brown fat: dietary phytochemicals targeting non-shivering thermogenesis to control body weight. The Proceedings of the Nutrition Society. 79: 338-356. PMID 32290888 DOI: 10.1017/S0029665120006928  0.331
2020 Lucchini FC, Wueest S, Challa TD, Item F, Modica S, Borsigova M, Haim Y, Wolfrum C, Rudich A, Konrad D. ASK1 inhibits browning of white adipose tissue in obesity. Nature Communications. 11: 1642. PMID 32242025 DOI: 10.1038/s41467-020-15483-7  0.526
2020 Challa TD, Dapito DH, Kulenkampff E, Kiehlmann E, Moser C, Straub L, Sun W, Wolfrum C. A Genetic Model to Study the Contribution of Brown and Brite Adipocytes to Metabolism. Cell Reports. 30: 3424-3433.e4. PMID 32160547 DOI: 10.1016/j.celrep.2020.02.055  0.737
2020 Scheele C, Wolfrum C. Brown Adipose Crosstalk in Tissue Plasticity and Human Metabolism. Endocrine Reviews. 41. PMID 31638161 DOI: 10.1210/endrev/bnz007  0.436
2019 de Jong JMA, Sun W, Pires ND, Frontini A, Balaz M, Jespersen NZ, Feizi A, Petrovic K, Fischer AW, Bokhari MH, Niemi T, Nuutila P, Cinti S, Nielsen S, Scheele C, ... ... Wolfrum C, et al. Author Correction: Human brown adipose tissue is phenocopied by classical brown adipose tissue in physiologically humanized mice. Nature Metabolism. 1: 927. PMID 32747808 DOI: 10.1038/s42255-019-0119-7  0.737
2019 de Jong JMA, Sun W, Pires ND, Frontini A, Balaz M, Jespersen NZ, Feizi A, Petrovic K, Fischer AW, Bokhari MH, Niemi T, Nuutila P, Cinti S, Nielsen S, Scheele C, ... ... Wolfrum C, et al. Human brown adipose tissue is phenocopied by classical brown adipose tissue in physiologically humanized mice. Nature Metabolism. 1: 830-843. PMID 32694768 DOI: 10.1038/s42255-019-0101-4  0.749
2019 Buhlmann E, Horváth C, Houriet J, Kiehlmann E, Radtke J, Marcourt L, Wolfender JL, Wolfrum C, Schröder S. Puerariae lobatae root extracts and the regulation of brown fat activity. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 64: 153075. PMID 31476558 DOI: 10.1016/j.phymed.2019.153075  0.353
2019 Straub LG, Efthymiou V, Grandl G, Balaz M, Challa TD, Truscello L, Horvath C, Moser C, Rachamin Y, Arnold M, Sun W, Modica S, Wolfrum C. Antioxidants protect against diabetes by improving glucose homeostasis in mouse models of inducible insulin resistance and obesity. Diabetologia. PMID 31309261 DOI: 10.1007/s00125-019-4937-7  0.684
2019 Banhos Danneskiold-Samsøe N, Sonne SB, Larsen JM, Hansen AN, Fjære E, Isidor MS, Petersen S, Henningsen J, Severi I, Sartini L, Schober Y, Wolf J, Nockher WA, Wolfrum C, Cinti S, et al. Overexpression of cyclooxygenase-2 in adipocytes reduces fat accumulation in inguinal white adipose tissue and hepatic steatosis in high-fat fed mice. Scientific Reports. 9: 8979. PMID 31222118 DOI: 10.1038/s41598-019-45062-w  0.423
2019 Sun W, von Meyenn F, Peleg-Raibstein D, Wolfrum C. Environmental and Nutritional Effects Regulating Adipose Tissue Function and Metabolism Across Generations. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 6: 1900275. PMID 31179229 DOI: 10.1002/advs.201900275  0.757
2019 Sarker G, Sun W, Rosenkranz D, Pelczar P, Opitz L, Efthymiou V, Wolfrum C, Peleg-Raibstein D. Maternal overnutrition programs hedonic and metabolic phenotypes across generations through sperm tsRNAs. Proceedings of the National Academy of Sciences of the United States of America. PMID 31061112 DOI: 10.1073/pnas.1820810116  0.678
2019 Sun W, Wolfrum C. Fat cells with a sweet tooth. Nature. 565: 167-168. PMID 30622347 DOI: 10.1038/d41586-018-07739-6  0.67
2019 Kulenkampff E, Wolfrum C. Proliferation of nutrition sensing preadipocytes upon short term HFD feeding. Adipocyte. 8: 16-25. PMID 30269635 DOI: 10.1080/21623945.2018.1521229  0.406
2019 Wolfrum C, Straub LG. Lessons from Cre-Mice and Indicator Mice. Handbook of Experimental Pharmacology. 251: 37-54. PMID 30027460 DOI: 10.1007/164_2018_146  0.361
2018 Balaz M, Becker AS, Balazova L, Straub L, Müller J, Gashi G, Maushart CI, Sun W, Dong H, Moser C, Horvath C, Efthymiou V, Rachamin Y, Modica S, Zellweger C, ... ... Wolfrum C, et al. Inhibition of Mevalonate Pathway Prevents Adipocyte Browning in Mice and Men by Affecting Protein Prenylation. Cell Metabolism. PMID 30581121 DOI: 10.1016/j.cmet.2018.11.017  0.747
2018 Perdikari A, Leparc GG, Balaz M, Pires ND, Lidell ME, Sun W, Fernandez-Albert F, Müller S, Akchiche N, Dong H, Balazova L, Opitz L, Röder E, Klein H, Stefanicka P, ... ... Wolfrum C, et al. BATLAS: Deconvoluting Brown Adipose Tissue. Cell Reports. 25: 784-797.e4. PMID 30332656 DOI: 10.1016/j.celrep.2018.09.044  0.749
2018 Sarker G, Berrens R, von Arx J, Pelczar P, Reik W, Wolfrum C, Peleg-Raibstein D. Transgenerational transmission of hedonic behaviors and metabolic phenotypes induced by maternal overnutrition. Translational Psychiatry. 8: 195. PMID 30315171 DOI: 10.1038/s41398-018-0243-2  0.314
2018 Sun W, Dong H, Becker AS, Dapito DH, Modica S, Grandl G, Opitz L, Efthymiou V, Straub LG, Sarker G, Balaz M, Balazova L, Perdikari A, Kiehlmann E, Bacanovic S, ... ... Wolfrum C, et al. Publisher Correction: Cold-induced epigenetic programming of the sperm enhances brown adipose tissue activity in the offspring. Nature Medicine. PMID 30087436 DOI: 10.1038/s41591-018-0163-y  0.654
2018 Sun W, Dong H, Becker AS, Dapito DH, Modica S, Grandl G, Opitz L, Efthymiou V, Straub LG, Sarker G, Balaz M, Balazova L, Perdikari A, Kiehlmann E, Bacanovic S, ... ... Wolfrum C, et al. Author Correction: Cold-induced epigenetic programming of the sperm enhances brown adipose tissue activity in the offspring. Nature Medicine. PMID 30087435 DOI: 10.1038/s41591-018-0162-z  0.656
2018 Wolfrum C, Kiehlmann E, Pelczar P. TRPC1 regulates brown adipose tissue activity in a PPARγ-dependent manner. American Journal of Physiology. Endocrinology and Metabolism. 315: E825-E832. PMID 29989850 DOI: 10.1152/ajpendo.00170.2017  0.431
2018 Sun W, Dong H, Becker AS, Dapito DH, Modica S, Grandl G, Opitz L, Efthymiou V, Straub LG, Sarker G, Balaz M, Balazova L, Perdikari A, Kiehlmann E, Bacanovic S, ... ... Wolfrum C, et al. Cold-induced epigenetic programming of the sperm enhances brown adipose tissue activity in the offspring. Nature Medicine. PMID 29988127 DOI: 10.1038/s41591-018-0102-y  0.751
2018 Schwalie PC, Dong H, Zachara M, Russeil J, Alpern D, Akchiche N, Caprara C, Sun W, Schlaudraff KU, Soldati G, Wolfrum C, Deplancke B. A stromal cell population that inhibits adipogenesis in mammalian fat depots. Nature. PMID 29925944 DOI: 10.1038/S41586-018-0226-8  0.752
2018 Balazova L, Wolfrum C, Balaz M. Weight Loss and Adipose Tissue Browning in Humans: The Chicken or the Egg? Trends in Endocrinology and Metabolism: Tem. 29: 450-452. PMID 29548805 DOI: 10.1016/j.tem.2018.03.004  0.43
2018 Stadion M, Schwerbel K, Graja A, Baumeier C, Rödiger M, Jonas W, Wolfrum C, Staiger H, Fritsche A, Häring HU, Klöting N, Blüher M, Fischer-Posovszky P, Schulz TJ, Joost HG, et al. Increased Ifi202b/IFI16 expression stimulates adipogenesis in mice and humans. Diabetologia. 61: 1167-1179. PMID 29478099 DOI: 10.1007/s00125-018-4571-9  0.402
2018 Lasar D, Rosenwald M, Kiehlmann E, Balaz M, Tall B, Opitz L, Lidell ME, Zamboni N, Krznar P, Sun W, Varga L, Stefanicka P, Ukropec J, Nuutila P, Virtanen K, ... ... Wolfrum C, et al. Peroxisome Proliferator Activated Receptor Gamma Controls Mature Brown Adipocyte Inducibility through Glycerol Kinase. Cell Reports. 22: 760-773. PMID 29346772 DOI: 10.1016/j.celrep.2017.12.067  0.723
2018 Schosserer M, Grillari J, Wolfrum C, Scheideler M. Age-Induced Changes in White, Brite, and Brown Adipose Depots: A Mini-Review. Gerontology. 64: 229-236. PMID 29212073 DOI: 10.1159/000485183  0.316
2017 Sanchez-Gurmaches J, Tang Y, Jespersen NZ, Wallace M, Martinez Calejman C, Gujja S, Li H, Edwards YJK, Wolfrum C, Metallo CM, Nielsen S, Scheele C, Guertin DA. Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis. Cell Metabolism. PMID 29153407 DOI: 10.1016/J.Cmet.2017.10.008  0.402
2017 Kälin S, Becker M, Ott VB, Serr I, Hosp F, Mollah MMH, Keipert S, Lamp D, Rohner-Jeanrenaud F, Flynn VK, Scherm MG, Nascimento LFR, Gerlach K, Popp V, Dietzen S, ... ... Wolfrum C, et al. A Stat6/Pten Axis Links Regulatory T Cells with Adipose Tissue Function. Cell Metabolism. 26: 475-492.e7. PMID 28877454 DOI: 10.1016/J.Cmet.2017.08.008  0.355
2017 Sigruener A, Wolfrum C, Boettcher A, Kopf T, Liebisch G, Orsó E, Schmitz G. Lipidomic and metabolic changes in the P4-type ATPase ATP10D deficient C57BL/6J wild type mice upon rescue of ATP10D function. Plos One. 12: e0178368. PMID 28542499 DOI: 10.1371/journal.pone.0178368  0.33
2017 Modica S, Wolfrum C. The dual role of BMP4 in adipogenesis and metabolism. Adipocyte. 6: 141-146. PMID 28425843 DOI: 10.1080/21623945.2017.1287637  0.313
2017 Thomou T, Mori MA, Dreyfuss JM, Konishi M, Sakaguchi M, Wolfrum C, Rao TN, Winnay JN, Garcia-Martin R, Grinspoon SK, Gorden P, Kahn CR. Adipose-derived circulating miRNAs regulate gene expression in other tissues. Nature. PMID 28199304 DOI: 10.1038/Nature21365  0.307
2017 Rosenwald M, Efthymiou V, Opitz L, Wolfrum C. SRF and MKL1 Independently Inhibit Brown Adipogenesis. Plos One. 12: e0170643. PMID 28125644 DOI: 10.1371/journal.pone.0170643  0.329
2016 Grandl G, Müller S, Moest H, Moser C, Wollscheid B, Wolfrum C. Depot specific differences in the adipogenic potential of precursors are mediated by collagenous extracellular matrix and Flotillin 2 dependent signaling. Molecular Metabolism. 5: 937-947. PMID 27689006 DOI: 10.1016/j.molmet.2016.07.008  0.348
2016 Rohm M, Schäfer M, Laurent V, Üstünel BE, Niopek K, Algire C, Hautzinger O, Sijmonsma TP, Zota A, Medrikova D, Pellegata NS, Ryden M, Kulyte A, Dahlman I, Arner P, ... ... Wolfrum C, et al. An AMP-activated protein kinase-stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice. Nature Medicine. PMID 27571348 DOI: 10.1038/Nm.4171  0.328
2016 Modica S, Straub LG, Balaz M, Sun W, Varga L, Stefanicka P, Profant M, Simon E, Neubauer H, Ukropcova B, Ukropec J, Wolfrum C. Bmp4 Promotes a Brown to White-like Adipocyte Shift. Cell Reports. PMID 27524617 DOI: 10.1016/j.celrep.2016.07.048  0.751
2016 Karaman S, Hollmén M, Yoon SY, Alkan HF, Alitalo K, Wolfrum C, Detmar M. Transgenic overexpression of VEGF-C induces weight gain and insulin resistance in mice. Scientific Reports. 6: 31566. PMID 27511834 DOI: 10.1038/Srep31566  0.375
2016 Müller S, Balaz M, Stefanicka P, Varga L, Amri EZ, Ukropec J, Wollscheid B, Wolfrum C. Proteomic Analysis of Human Brown Adipose Tissue Reveals Utilization of Coupled and Uncoupled Energy Expenditure Pathways. Scientific Reports. 6: 30030. PMID 27418403 DOI: 10.1038/srep30030  0.44
2016 Meissburger B, Perdikari A, Moest H, Müller S, Geiger M, Wolfrum C. Regulation of adipogenesis by paracrine factors from adipose stromal-vascular fraction - a link to fat depot-specific differences. Biochimica Et Biophysica Acta. 1861: 1121-1131. PMID 27317982 DOI: 10.1016/j.bbalip.2016.06.010  0.382
2016 Becker AS, Nagel HW, Wolfrum C, Burger IA. Anatomical Grading for Metabolic Activity of Brown Adipose Tissue. Plos One. 11: e0149458. PMID 26901352 DOI: 10.1371/journal.pone.0149458  0.341
2016 Korner G, Scherer T, Adamsen D, Rebuffat A, Crabtree M, Rassi A, Scavelli R, Homma D, Ledermann B, Konrad D, Ichinose H, Wolfrum C, Horsch M, Rathkolb B, Klingenspor M, et al. Mildly compromised tetrahydrobiopterin cofactor biosynthesis due to Pts variants leads to unusual body fat distribution and abdominal obesity in mice. Journal of Inherited Metabolic Disease. 39: 309-19. PMID 26830550 DOI: 10.1007/S10545-015-9909-6  0.358
2016 Korner G, Scherer T, Adamsen D, Rebuffat A, Crabtree M, Rassi A, Scavelli R, Homma D, Ledermann B, Konrad D, Ichinose H, Wolfrum C, Horsch M, Rathkolb B, Klingenspor M, et al. Mildly compromised tetrahydrobiopterin cofactor biosynthesis due to Pts variants leads to unusual body fat distribution and abdominal obesity in mice Journal of Inherited Metabolic Disease. 39: 309-319. DOI: 10.1007/s10545-015-9909-6  0.324
2016 Wucherpfennig TG, Müller S, Wolfrum C, Bode JW. Chemical Synthesis of the 12 kDa Human Myokine Irisin by α‐Ketoacid‐Hydroxylamine (KAHA) Ligation Helvetica Chimica Acta. 99: 897-907. DOI: 10.1002/Hlca.201600160  0.302
2015 Challa TD, Straub LG, Balaz M, Kiehlmann E, Donze O, Rudofsky G, Ukropec J, Ukropcova B, Wolfrum C. Regulation of de novo adipocyte differentiation through crosstalk between adipocytes and pre-adipocytes. Diabetes. PMID 26340931 DOI: 10.2337/db14-1932  0.433
2015 Balaž M, Ukropcova B, Kurdiova T, Vlcek M, Surova M, Krumpolec P, Vanuga P, Gašperíková D, Klimeš I, Payer J, Wolfrum C, Ukropec J. Improved adipose tissue metabolism after 5-year growth hormone replacement therapy in growth hormone deficient adults: The role of zinc-α2-glycoprotein. Adipocyte. 4: 113-22. PMID 26167410 DOI: 10.4161/21623945.2014.973772  0.388
2015 Müller S, Kulenkampff E, Wolfrum C. Adipose Tissue Stem Cells. Handbook of Experimental Pharmacology. PMID 25912015 DOI: 10.1007/164_2015_13  0.326
2015 Karaman S, Hollmén M, Robciuc MR, Alitalo A, Nurmi H, Morf B, Buschle D, Alkan HF, Ochsenbein AM, Alitalo K, Wolfrum C, Detmar M. Blockade of VEGF-C and VEGF-D modulates adipose tissue inflammation and improves metabolic parameters under high-fat diet. Molecular Metabolism. 4: 93-105. PMID 25685697 DOI: 10.1016/J.Molmet.2014.11.006  0.314
2015 Balaz M, Ukropcova B, Kurdiova T, Gajdosechova L, Vlcek M, Janakova Z, Fedeles J, Pura M, Gasperikova D, Smith SR, Tkacova R, Klimes I, Payer J, Wolfrum C, Ukropec J. Adipokine zinc-α2-glycoprotein regulated by growth hormone and linked to insulin sensitivity. Obesity (Silver Spring, Md.). 23: 322-8. PMID 25098857 DOI: 10.1002/oby.20856  0.331
2014 Uhrig-Schmidt S, Geiger M, Luippold G, Birk G, Mennerich D, Neubauer H, Grimm D, Wolfrum C, Kreuz S. Gene delivery to adipose tissue using transcriptionally targeted rAAV8 vectors. Plos One. 9: e116288. PMID 25551639 DOI: 10.1371/Journal.Pone.0116288  0.415
2014 Gubelmann C, Schwalie PC, Raghav SK, Röder E, Delessa T, Kiehlmann E, Waszak SM, Corsinotti A, Udin G, Holcombe W, Rudofsky G, Trono D, Wolfrum C, Deplancke B. Identification of the transcription factor ZEB1 as a central component of the adipogenic gene regulatory network. Elife. 3: e03346. PMID 25163748 DOI: 10.7554/Elife.03346  0.321
2014 Balaz M, Vician M, Janakova Z, Kurdiova T, Surova M, Imrich R, Majercikova Z, Penesova A, Vlcek M, Kiss A, Belan V, Klimes I, Olejnik J, Gasperikova D, Wolfrum C, et al. Subcutaneous adipose tissue zinc-α2-glycoprotein is associated with adipose tissue and whole-body insulin sensitivity. Obesity (Silver Spring, Md.). 22: 1821-9. PMID 24753506 DOI: 10.1002/oby.20764  0.386
2014 Blum KS, Karaman S, Proulx ST, Ochsenbein AM, Luciani P, Leroux JC, Wolfrum C, Detmar M. Chronic high-fat diet impairs collecting lymphatic vessel function in mice. Plos One. 9: e94713. PMID 24714646 DOI: 10.1371/Journal.Pone.0094713  0.354
2014 Rosenwald M, Wolfrum C. The origin and definition of brite versus white and classical brown adipocytes. Adipocyte. 3: 4-9. PMID 24575363 DOI: 10.4161/adip.26232  0.418
2013 Rosenwald M, Perdikari A, Weber E, Wolfrum C. Phenotypic Analysis of BAT versus WAT Differentiation. Current Protocols in Mouse Biology. 3: 205-16. PMID 26069094 DOI: 10.1002/9780470942390.mo130167  0.463
2013 Mrosek N, Meissburger B, Mataki C, Roeder E, Ukropec J, Klimes I, Gasperikova D, Nawroth PP, Rudofsky G, Auwerx J, Schoonjans K, Wolfrum C. Transcriptional regulation of adipocyte formation by the liver receptor homologue 1 (Lrh1)-Small hetero-dimerization partner (Shp) network. Molecular Metabolism. 2: 314-23. PMID 24049743 DOI: 10.1016/j.molmet.2013.03.003  0.45
2013 Moest H, Frei AP, Bhattacharya I, Geiger M, Wollscheid B, Wolfrum C. Malfunctioning of adipocytes in obesity is linked to quantitative surfaceome changes. Biochimica Et Biophysica Acta. 1831: 1208-16. PMID 24046861 DOI: 10.1016/j.bbalip.2013.04.001  0.438
2013 Rosenwald M, Perdikari A, Rülicke T, Wolfrum C. Bi-directional interconversion of brite and white adipocytes. Nature Cell Biology. 15: 659-67. PMID 23624403 DOI: 10.1038/ncb2740  0.452
2013 Rohm M, Sommerfeld A, Strzoda D, Jones A, Sijmonsma TP, Rudofsky G, Wolfrum C, Sticht C, Gretz N, Zeyda M, Leitner L, Nawroth PP, Stulnig TM, Diaz MB, Vegiopoulos A, et al. Transcriptional cofactor TBLR1 controls lipid mobilization in white adipose tissue. Cell Metabolism. 17: 575-85. PMID 23499424 DOI: 10.1016/j.cmet.2013.02.010  0.44
2012 Kumpf S, Mihlan M, Goginashvili A, Grandl G, Gehart H, Godel A, Schmidt J, Müller J, Bezzi M, Ittner A, Guccione E, Wolfrum C, Ricci R. Hairless promotes PPARγ expression and is required for white adipogenesis. Embo Reports. 13: 1012-20. PMID 22964757 DOI: 10.1038/embor.2012.133  0.302
2012 Challa TD, Beaton N, Arnold M, Rudofsky G, Langhans W, Wolfrum C. Regulation of adipocyte formation by GLP-1/GLP-1R signaling. The Journal of Biological Chemistry. 287: 6421-30. PMID 22207759 DOI: 10.1074/Jbc.M111.310342  0.37
2011 Meissburger B, Ukropec J, Roeder E, Beaton N, Geiger M, Teupser D, Civan B, Langhans W, Nawroth PP, Gasperikova D, Rudofsky G, Wolfrum C. Adipogenesis and insulin sensitivity in obesity are regulated by retinoid-related orphan receptor gamma. Embo Molecular Medicine. 3: 637-51. PMID 21853531 DOI: 10.1002/Emmm.201100172  0.411
2011 Meissburger B, Stachorski L, Röder E, Rudofsky G, Wolfrum C. Tissue inhibitor of matrix metalloproteinase 1 (TIMP1) controls adipogenesis in obesity in mice and in humans. Diabetologia. 54: 1468-79. PMID 21437772 DOI: 10.1007/s00125-011-2093-9  0.31
2011 Osto M, Zini E, Franchini M, Wolfrum C, Guscetti F, Hafner M, Ackermann M, Reusch CE, Lutz TA. Subacute endotoxemia induces adipose inflammation and changes in lipid and lipoprotein metabolism in cats. Endocrinology. 152: 804-15. PMID 21266508 DOI: 10.1210/en.2010-0999  0.416
2009 Silva JP, von Meyenn F, Howell J, Thorens B, Wolfrum C, Stoffel M. Regulation of adaptive behaviour during fasting by hypothalamic Foxa2. Nature. 462: 646-50. PMID 19956259 DOI: 10.1038/Nature08589  0.361
2003 Wolfrum C, Shih DQ, Kuwajima S, Norris AW, Kahn CR, Stoffel M. Role of Foxa-2 in adipocyte metabolism and differentiation. The Journal of Clinical Investigation. 112: 345-56. PMID 12865419 DOI: 10.1172/Jci18698  0.415
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