Susan Brain - Publications

Affiliations: 
King's College London, London, UK 

62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Thakore P, Clark JE, Aubdool AA, Thapa D, Starr A, Fraser PA, Farrell-Dillon K, Fernandes ES, McFadzean I, Brain SD. Transient Receptor Potential Canonical 5 (TRPC5): Regulation of Heart Rate and Protection against Pathological Cardiac Hypertrophy. Biomolecules. 14. PMID 38672459 DOI: 10.3390/biom14040442  0.772
2022 Zarban AA, Chaudhry H, de Sousa Valente J, Argunhan F, Ghanim H, Brain SD. Elucidating the Ability of CGRP to Modulate Microvascular Events in Mouse Skin. International Journal of Molecular Sciences. 23. PMID 36293102 DOI: 10.3390/ijms232012246  0.36
2021 Thapa D, Barrett B, Argunhan F, Brain SD. Influence of Cold-TRP Receptors on Cold-Influenced Behaviour. Pharmaceuticals (Basel, Switzerland). 15. PMID 35056099 DOI: 10.3390/ph15010042  0.331
2021 Argunhan F, Thapa D, Aubdool AA, Carlini E, Arkless K, Hendrikse ER, de Sousa Valente J, Kodji X, Barrett B, Ricciardi CA, Gnudi L, Lucy Hay D, Brain SD. Calcitonin Gene-Related Peptide Protects Against Cardiovascular Dysfunction Independently of Nitric Oxide In Vivo. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA12014. PMID 33641368 DOI: 10.1161/HYPERTENSIONAHA.120.14851  0.801
2019 La Russa F, Lopes DM, Hobbs C, Argunhan F, Brain S, Bevan S, Bennett DLH, McMahon SB. Disruption of the Sensory System Affects Sterile Cutaneous Inflammation in vivo. The Journal of Investigative Dermatology. PMID 30974165 DOI: 10.1016/J.Jid.2019.01.037  0.355
2018 Kodji X, Arkless KL, Kee Z, Cleary SJ, Aubdool AA, Evans E, Caton P, Pitchford SC, Brain SD. Sensory nerves mediate spontaneous behaviors in addition to inflammation in a murine model of psoriasis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201800395RR. PMID 30204499 DOI: 10.1096/Fj.201800395Rr  0.775
2018 Pereira DMS, Mendes SJF, Alawi K, Thakore P, Aubdool A, Sousa NCF, da Silva JFR, Castro JA, P Pereira IC, Silva LCN, Grisotto MAG, Monteiro-Neto V, Costa SKP, da Costa R, Calixto JB, ... Brain SD, et al. Transient Receptor Potential Canonical Channels 4 and 5 Mediate -Derived Thioredoxin Effects in Lipopolysaccharide-Injected Mice. Oxidative Medicine and Cellular Longevity. 2018: 4904696. PMID 29983857 DOI: 10.1155/2018/4904696  0.783
2018 Kemény Á, Kodji X, Horváth S, Komlódi R, Szőke É, Sándor Z, Perkecz A, Gyömörei C, Sétáló G, Kelemen B, Bíró T, Tóth BI, Brain SD, Pintér E, Gyulai R. TRPA1 acts in a protective manner in imiquimod-induced psoriasiform dermatitis in mice. The Journal of Investigative Dermatology. PMID 29550417 DOI: 10.1016/j.jid.2018.02.040  0.348
2018 Aubdool AA, Argunhan F, Thakore P, Brain SD. Response by Aubdool et al to Letters Regarding Article, "A Novel α-Calcitonin Gene-Related Peptide Analogue Protects Against End-Organ Damage in Experimental Hypertension, Cardiac Hypertrophy, and Heart Failure". Circulation. 137: 1201-1202. PMID 29530898 DOI: 10.1161/CIRCULATIONAHA.117.031848  0.75
2017 Wilde E, Aubdool AA, Thakore P, Baldissera L, Alawi KM, Keeble J, Nandi M, Brain SD. Tail-Cuff Technique and Its Influence on Central Blood Pressure in the Mouse. Journal of the American Heart Association. 6. PMID 28655735 DOI: 10.1161/JAHA.116.005204  0.749
2017 Aubdool AA, Thakore P, Argunhan F, Smillie SJ, Schnelle M, Srivastava S, Alawi KM, Wilde E, Mitchell J, Farrell-Dillon K, Richards DA, Maltese G, Siow RC, Nandi M, Clark JE, ... ... Brain SD, et al. A Novel α-Calcitonin Gene-Related Peptide Analogue Protects Against End-Organ Damage in Experimental Hypertension, Cardiac Hypertrophy and Heart Failure. Circulation. PMID 28446517 DOI: 10.1161/Circulationaha.117.028388  0.775
2017 Alawi K, Aubdool A, Liang L, Wilde E, Vepa A, Psefteli P, Brain S, Keeble J. Control of the sympathetic nervous system by TRPV1 in the regulation of body temperature Neuropeptides. 65: 131-132. DOI: 10.1016/J.Npep.2017.02.013  0.744
2017 Pinter E, Pozsgai G, Hajna Z, Saghy E, Horvath A, Szoke E, Sar C, Bagoly T, Aubdool A, Brain S, Helyes Z. TRPA1 receptor-mediated effects of H2S donors and polysulfides Neuropeptides. 65: 131. DOI: 10.1016/J.Npep.2017.02.010  0.764
2017 Aubdool A, Brain S. What is the relevance of vascular responses to CGRP? Neuropeptides. 65: 129-130. DOI: 10.1016/J.Npep.2017.02.007  0.743
2016 Hajna Z, Sághy É, Payrits M, Aubdool AA, Szőke É, Pozsgai G, Bátai IZ, Nagy L, Filotás D, Helyes Z, Brain SD, Pintér E. Capsaicin-Sensitive Sensory Nerves Mediate the Cellular and Microvascular Effects of H2S via TRPA1 Receptor Activation and Neuropeptide Release. Journal of Molecular Neuroscience : Mn. PMID 27525636 DOI: 10.1007/s12031-016-0802-z  0.796
2016 Aubdool AA, Kodji X, Abdul-Kader N, Heads R, Fernandes ES, Bevan S, Brain SD. TRPA1 activation leads to neurogenic vasodilatation: Involvement of reactive oxygen nitrogen species in addition to CGRP and nitric oxide. British Journal of Pharmacology. PMID 27189253 DOI: 10.1111/Bph.13519  0.767
2016 Alawi KM, Russell FA, Aubdool AA, Srivastava S, Riffo-Vasquez Y, Baldissera L, Thakore P, Saleque N, Fernandes ES, Walsh DA, Brain SD. Transient receptor potential canonical 5 (TRPC5) protects against pain and vascular inflammation in arthritis and joint inflammation. Annals of the Rheumatic Diseases. PMID 27165180 DOI: 10.1136/Annrheumdis-2015-208886  0.781
2016 Fernandes ES, Russell FA, Alawi KM, Sand C, Liang L, Salamon R, Bodkin JV, Aubdool AA, Arno M, Gentry C, Smillie SJ, Bevan S, Keeble JE, Malcangio M, Brain SD. Environmental cold exposure increases blood flow and affects pain sensitivity in the knee joints of CFA-induced arthritic mice in a TRPA1-dependent manner. Arthritis Research & Therapy. 18: 7. PMID 26754745 DOI: 10.1186/S13075-015-0905-X  0.781
2016 Brain S. SP0106 Neuropeptides, TRPS and Inflammation: Focus on The Joint Annals of the Rheumatic Diseases. 75: 26-26. DOI: 10.1136/Annrheumdis-2016-Eular.6354  0.421
2015 Alawi KM, Aubdool AA, Liang L, Wilde E, Vepa A, Psefteli MP, Brain SD, Keeble JE. The sympathetic nervous system is controlled by transient receptor potential vanilloid 1 in the regulation of body temperature. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 4285-98. PMID 26136480 DOI: 10.1096/fj.15-272526  0.797
2014 Bodkin JV, Thakore P, Aubdool AA, Liang L, Fernandes ES, Nandi M, Spina D, Clark JE, Aaronson PI, Shattock MJ, Brain SD. Investigating the potential role of TRPA1 in locomotion and cardiovascular control during hypertension. Pharmacology Research & Perspectives. 2: e00052. PMID 25505598 DOI: 10.1002/prp2.52  0.781
2014 Aubdool AA, Graepel R, Kodji X, Alawi KM, Bodkin JV, Srivastava S, Gentry C, Heads R, Grant AD, Fernandes ES, Bevan S, Brain SD. TRPA1 is essential for the vascular response to environmental cold exposure. Nature Communications. 5: 5732. PMID 25501034 DOI: 10.1038/Ncomms6732  0.777
2014 Varga A, Jenes A, Marczylo TH, Sousa-Valente J, Chen J, Austin J, Selvarajah S, Piscitelli F, Andreou AP, Taylor AH, Kyle F, Yaqoob M, Brain S, White JP, Csernoch L, et al. Anandamide produced by Ca(2+)-insensitive enzymes induces excitation in primary sensory neurons. Pflã¼Gers Archiv : European Journal of Physiology. 466: 1421-35. PMID 24114173 DOI: 10.1007/S00424-013-1360-7  0.313
2013 Fernandes ES, Vong CT, Quek S, Cheong J, Awal S, Gentry C, Aubdool AA, Liang L, Bodkin JV, Bevan S, Heads R, Brain SD. Superoxide generation and leukocyte accumulation: Key elements in the mediation of leukotriene B4-induced itch by transient receptor potential ankyrin 1 and transient receptor potential vanilloid 1 Faseb Journal. 27: 1664-1673. PMID 23271050 DOI: 10.1096/fj.12-221218  0.796
2013 Smillie S, King R, Pozgai G, Winter PD, Siow R, Brain S. 204 Alpha Calcitonin Gene-Related Peptide Plays A Protective Role In Both An Acute And Sustained Model Of Hypertension, A Mechanism Which May Be Linked To The Loss Of Endothelial Nitric Oxide Synthase (Enos) As The Hypertension Progresses Heart. 99. DOI: 10.1136/Heartjnl-2013-304019.204  0.373
2012 Fernandes ES, Liang L, Smillie SJ, Kaiser F, Purcell R, Rivett DW, Alam S, Howat S, Collins H, Thompson SJ, Keeble JE, Riffo-Vasquez Y, Bruce KD, Brain SD. TRPV1 deletion enhances local inflammation and accelerates the onset of systemic inflammatory response syndrome. Journal of Immunology (Baltimore, Md. : 1950). 188: 5741-51. PMID 22547700 DOI: 10.4049/jimmunol.1102147  0.318
2011 Aubdool AA, Brain SD. Neurovascular aspects of skin neurogenic inflammation Journal of Investigative Dermatology Symposium Proceedings. 15: 33-39. PMID 22076325 DOI: 10.1038/jidsymp.2011.8  0.79
2011 Ryckmans T, Aubdool AA, Bodkin JV, Cox P, Brain SD, Dupont T, Fairman E, Hashizume Y, Ishii N, Kato T, Kitching L, Newman J, Omoto K, Rawson D, Strover J. Design and pharmacological evaluation of PF-4840154, a non-electrophilic reference agonist of the TrpA1 channel. Bioorganic & Medicinal Chemistry Letters. 21: 4857-9. PMID 21741838 DOI: 10.1016/j.bmcl.2011.06.035  0.752
2011 Sawyer I, Smillie SJ, Bodkin JV, Fernandes E, O'Byrne KT, Brain SD. The vasoactive potential of kisspeptin-10 in the peripheral vasculature Plos One. 6. PMID 21347414 DOI: 10.1371/journal.pone.0014671  0.326
2011 Graepel R, Fernandes ES, Aubdool AA, Andersson DA, Bevan S, Brain SD. 4-Oxo-2-nonenal (4-ONE): Evidence of transient receptor potential ankyrin 1-dependent and -independent nociceptive and vasoactive responses in vivo Journal of Pharmacology and Experimental Therapeutics. 337: 117-124. PMID 21205926 DOI: 10.1124/jpet.110.172403  0.809
2010 Pozsgai G, Bodkin JV, Graepel R, Bevan S, Andersson DA, Brain SD. Evidence for the pathophysiological relevance of TRPA1 receptors in the cardiovascular system in vivo Cardiovascular Research. 87: 760-768. PMID 20442136 DOI: 10.1093/cvr/cvq118  0.373
2010 Teles AM, Kumagai Y, Brain S, Teixeira SA, Varriano AA, Barreto MAAG, Lima WTd, Antunes E, Muscara MN, Costa SKP. Involvement of sensory nerves and TRPV1 receptors in the rat airway inflammatory response to two environment pollutants: diesel exhaust particles (DEP) and 1,2-naphthoquinone (1,2-NQ) (vol 84, pg 109, 2010) Archives of Toxicology. 84: 119-119. DOI: 10.1007/S00204-009-0506-Z  0.338
2009 Liang L, Tam CW, Pozsgai G, Siow R, Clark N, Keeble J, Husmann K, Born W, Fischer JA, Poston R, Shah A, Brain SD. Protection of angiotensin II-induced vascular hypertrophy in vascular smooth muscle-targeted receptor activity-modifying protein 2 transgenic mice. Hypertension. 54: 1254-61. PMID 19858409 DOI: 10.1161/HYPERTENSIONAHA.109.129783  0.336
2009 Schmidhuber SM, Rauch I, Kofler B, Brain SD. Evidence that the modulatory effect of galanin on inflammatory edema formation is mediated by the galanin receptor 3 in the murine microvasculature Journal of Molecular Neuroscience. 37: 177-181. PMID 18679831 DOI: 10.1007/S12031-008-9135-X  0.324
2008 Bowe JE, Li XF, Kinsey-Jones JS, Brain SD, Lightman SL, O'Byrne KT. The role of corticotrophin-releasing hormone receptors in the calcitonin gene-related peptide-induced suppression of pulsatile luteinising hormone secretion in the female rat. Stress (Amsterdam, Netherlands). 11: 312-9. PMID 18574791 DOI: 10.1080/10253890701801448  0.305
2008 Costa R, Marotta DM, Manjavachi MN, Fernandes ES, Lima-Garcia JF, Paszcuk AF, Quintão NL, Juliano L, Brain SD, Calixto JB. Evidence for the role of neurogenic inflammation components in trypsin-elicited scratching behaviour in mice. British Journal of Pharmacology. 154: 1094-103. PMID 18454165 DOI: 10.1038/Bjp.2008.172  0.392
2008 Starr A, Graepel R, Keeble J, Schmidhuber S, Clark N, Grant A, Shah AM, Brain SD. A reactive oxygen species-mediated component in neurogenic vasodilatation. Cardiovascular Research. 78: 139-47. PMID 18203709 DOI: 10.1093/cvr/cvn012  0.301
2008 Szabó A, Czirják L, Sándor Z, Helyes Z, László T, Elekes K, Czömpöly T, Starr A, Brain S, Szolcsányi J, Pintér E. Investigation of sensory neurogenic components in a bleomycin-induced scleroderma model using transient receptor potential vanilloid 1 receptor- and calcitonin gene-related peptide-knockout mice. Arthritis and Rheumatism. 58: 292-301. PMID 18163477 DOI: 10.1002/Art.23168  0.463
2008 Brain S, Grant AD, Tam C, Pinter E, Starr A, Keeble J, Clark N. Neurogenic modulation and vasoactive peptides in microvascular biology Experimental Dermatology. 13: 574-574. DOI: 10.1111/J.0906-6705.2004.0212Ab.X  0.452
2007 Pozsgai G, Sándor K, Perkecz A, Szolcsányi J, Helyes Z, Brain SD, Pintér E. Topical acetone treatment induces neurogenic oedema on the sensitized mouse ear: An in vivo study using transient receptor potential vanilloid 1 (TRPV1) receptor knockout mice Inflammation Research. 56: 459-467. PMID 18224287 DOI: 10.1007/S00011-007-7065-7  0.451
2007 Clark N, Keeble J, Fernandes ES, Starr A, Liang L, Sugden D, de Winter P, Brain SD. The transient receptor potential vanilloid 1 (TRPV1) receptor protects against the onset of sepsis after endotoxin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 3747-55. PMID 17601984 DOI: 10.1096/fj.06-7460com  0.376
2007 Schmidhuber SM, Santic R, Tam CW, Bauer JW, Kofler B, Brain SD. Galanin-like peptides exert potent vasoactive functions in vivo Journal of Investigative Dermatology. 127: 716-721. PMID 17024098 DOI: 10.1038/Sj.Jid.5700569  0.331
2006 Bowe J, Li XF, Kinsey-Jones J, Heyerick A, Brain S, Milligan S, O'Byrne K. The hop phytoestrogen, 8-prenylnaringenin, reverses the ovariectomy-induced rise in skin temperature in an animal model of menopausal hot flushes Journal of Endocrinology. 191: 399-405. PMID 17088409 DOI: 10.1677/Joe.1.06919  0.372
2006 Costa SK, Starr A, Hyslop S, Gilmore D, Brain SD. How important are NK1 receptors for influencing microvascular inflammation and itch in the skin? Studies using Phoneutria nigriventer venom. Vascular Pharmacology. 45: 209-14. PMID 16914387 DOI: 10.1016/j.vph.2005.08.025  0.305
2006 Li XF, Bowe JE, Kinsey-Jones JS, Brain SD, Lightman SL, O'Byrne KT. Differential role of corticotrophin-releasing factor receptor types 1 and 2 in stress-induced suppression of pulsatile luteinising hormone secretion in the female rat. Journal of Neuroendocrinology. 18: 602-10. PMID 16867181 DOI: 10.1111/J.1365-2826.2006.01450.X  0.307
2006 Keeble JE, Brain SD. Capsaicin-induced vasoconstriction in the mouse knee joint: A study using TRPV1 knockout mice Neuroscience Letters. 401: 55-58. PMID 16584841 DOI: 10.1016/j.neulet.2006.02.083  0.342
2006 Tam CW, Husmann K, Clark NC, Clark JE, Lazar Z, Ittner LM, Götz J, Douglas G, Grant AD, Sugden D, Poston L, Poston R, McFadzean I, Marber MS, Fischer JA, ... ... Brain SD, et al. Enhanced vascular responses to adrenomedullin in mice overexpressing receptor-activity-modifying protein 2. Circulation Research. 98: 262-70. PMID 16373602 DOI: 10.1161/01.Res.0000200737.63865.58  0.388
2006 Costa SKP, Yshii LM, Poston RN, Muscará MN, Brain SD. Pivotal role of endogenous tachykinins and the NK1 receptor in mediating leukocyte accumulation, in the absence of oedema formation, in response to TNFα in the cutaneous microvasculature Journal of Neuroimmunology. 171: 99-109. PMID 16269189 DOI: 10.1016/j.jneuroim.2005.09.006  0.326
2005 Bánvölgyi A, Pálinkás L, Berki T, Clark N, Grant AD, Helyes Z, Pozsgai G, Szolcsányi J, Brain SD, Pintér E. Evidence for a novel protective role of the vanilloid TRPV1 receptor in a cutaneous contact allergic dermatitis model Journal of Neuroimmunology. 169: 86-96. PMID 16188326 DOI: 10.1016/j.jneuroim.2005.08.012  0.361
2005 Kinsey-Jones JS, Li XF, Bowe JE, Brain SD, Lightman SL, O'Byrne KT. Effect of calcitonin gene-related peptide on gonadotrophin-releasing hormone mRNA expression in GT1-7 cells. Journal of Neuroendocrinology. 17: 541-4. PMID 16101891 DOI: 10.1111/J.1365-2826.2005.01341.X  0.369
2005 Bowe JE, Li XF, Kinsey-Jones JS, Paterson S, Brain SD, Lightman SL, O'Byrne KT. Calcitonin gene-related peptide-induced suppression of luteinizing hormone pulses in the rat: the role of endogenous opioid peptides. The Journal of Physiology. 566: 921-8. PMID 15905218 DOI: 10.1113/Jphysiol.2005.085662  0.327
2004 Bánvölgyi A, Pozsgai G, Brain SD, Helyes ZS, Szolcsányi J, Ghosh M, Melegh B, Pintér E. Mustard oil induces a transient receptor potential vanilloid 1 receptor-independent neurogenic inflammation and a non-neurogenic cellular inflammatory component in mice Neuroscience. 125: 449-459. PMID 15062987 DOI: 10.1016/J.Neuroscience.2004.01.009  0.432
2003 Chu DQ, Cox HM, Costa SK, Herzog H, Brain SD. The ability of neuropeptide Y to mediate responses in the murine cutaneous microvasculature: an analysis of the contribution of Y1 and Y2 receptors. British Journal of Pharmacology. 140: 422-30. PMID 12970079 DOI: 10.1038/sj.bjp.0705452  0.316
2002 Cao T, Brain SD, Khodr B, Khalil Z. B1 and B2 antagonists and bradykinin-induced blood flow in rat skin inflammation. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 51: 295-9. PMID 12088270 DOI: 10.1007/Pl00000307  0.32
2002 Grant AD, Gerard NP, Brain SD. Evidence of a role for NK1 and CGRP receptors in mediating neurogenic vasodilatation in the mouse ear. British Journal of Pharmacology. 135: 356-62. PMID 11815370 DOI: 10.1038/sj.bjp.0704485  0.325
2001 Rawlingson A, Gerard NP, Brain SD. Interactive contribution of NK(1) and kinin receptors to the acute inflammatory oedema observed in response to noxious heat stimulation: studies in NK(1) receptor knockout mice. British Journal of Pharmacology. 134: 1805-13. PMID 11739258 DOI: 10.1038/sj.bjp.0704436  0.333
2001 Cao T, Grant AD, Gerard NP, Brain SD. Lack of a significant effect of deletion of the tachykinin neurokinin-1 receptor on wound healing in mouse skin. Neuroscience. 108: 695-700. PMID 11738504 DOI: 10.1016/S0306-4522(01)00435-3  0.377
2000 Cao T, Pintér E, Al-Rashed S, Gerard N, Hoult JR, Brain SD. Neurokinin-1 receptor agonists are involved in mediating neutrophil accumulation in the inflamed, but not normal, cutaneous microvasculature: an in vivo study using neurokinin-1 receptor knockout mice. Journal of Immunology (Baltimore, Md. : 1950). 164: 5424-9. PMID 10799908  0.342
2000 Costa SK, De Nucci G, Antunes E, Brain SD. Involvement of vanilloid receptors and purinoceptors in the Phoneutria nigriventer spider venom-induced plasma extravasation in rat skin. European Journal of Pharmacology. 391: 305-15. PMID 10729373 DOI: 10.1016/S0014-2999(00)00075-3  0.39
1995 Brain SD, Newbold P, Kajekar R. Modulation of the release and activity of neuropeptides in the microcirculation Canadian Journal of Physiology and Pharmacology. 73: 995-998. PMID 8846443  0.311
1995 Newbold P, Brain SD. An investigation into the mechanism of capsaicin-induced oedema in rabbit skin British Journal of Pharmacology. 114: 570-577. PMID 7537589  0.315
1989 Buckley T, Brain S, Williams T. Selective inhibition of capsaicin-induced responses by ruthenium red in rabbit skin Regulatory Peptides. 26: 61. DOI: 10.1016/0167-0115(89)90117-1  0.3
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