Murdoch Ritchie, Ph.D. - Publications

Affiliations: 
 

412 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Zhang C, Verma A, Feng Y, Melo MCDR, McQuillan M, Hansen M, Lucas A, Park J, Ranciaro A, Thompson S, Rubel M, Campbell M, Beggs W, Hirbo J, Mpoloka SW, ... ... Ritchie M, et al. Impact of natural selection on global patterns of genetic variation, and association with clinical phenotypes, at genes involved in SARS-CoV-2 infection. Research Square. PMID 34341784 DOI: 10.21203/rs.3.rs-673011/v1  1
2021 Zhang C, Verma A, Feng Y, Melo MCR, McQuillan M, Hansen M, Lucas A, Park J, Ranciaro A, Thompson S, Rubel MA, Campbell MC, Beggs W, Hirbo J, Mpoloka SW, ... Ritchie MD, et al. Global patterns of genetic variation and association with clinical phenotypes at genes involved in SARS-CoV-2 infection. Medrxiv : the Preprint Server For Health Sciences. PMID 34230933 DOI: 10.1101/2021.06.28.21259529  1
2021 Gherardin NA, Redmond SJ, McWilliam HEG, Almeida CF, Gourley KHA, Seneviratna R, Li S, De Rose R, Ross FJ, Nguyen-Robertson CV, Su S, Ritchie ME, Villadangos JA, Moody DB, Pellicci DG, et al. CD36 family members are TCR-independent ligands for CD1 antigen-presenting molecules. Science Immunology. 6. PMID 34172588 DOI: 10.1126/sciimmunol.abg4176  1
2021 Veturi Y, Lucas A, Bradford Y, Hui D, Dudek S, Theusch E, Verma A, Miller JE, Kullo I, Hakonarson H, Sleiman P, Schaid D, Stein CM, Edwards DRV, Feng Q, ... Ritchie MD, et al. A unified framework identifies new links between plasma lipids and diseases from electronic medical records across large-scale cohorts. Nature Genetics. PMID 34140684 DOI: 10.1038/s41588-021-00879-y  1
2021 Sun L, Surya S, Goodman NG, Le AN, Kelly G, Owoyemi O, Desai H, Zheng C, DeLuca S, Good ML, Hussain J, Jeffries SD, Kry YR, Kugler EM, Mansour M, ... ... Ritchie M, et al. SARS-CoV-2 Seropositivity and Seroconversion in Patients Undergoing Active Cancer-Directed Therapy. Jco Oncology Practice. OP2100113. PMID 34133219 DOI: 10.1200/OP.21.00113  1
2021 Kosmicki JA, Horowitz JE, Banerjee N, Lanche R, Marcketta A, Maxwell E, Bai X, Sun D, Backman JD, Sharma D, Kury FSP, Kang HM, O'Dushlaine C, Yadav A, Mansfield AJ, ... Ritchie MD, et al. Pan-ancestry exome-wide association analyses of COVID-19 outcomes in 586,157 individuals. American Journal of Human Genetics. PMID 34115965 DOI: 10.1016/j.ajhg.2021.05.017  1
2021 Hall MA, Wallace J, Lucas AM, Bradford Y, Verma SS, Müller-Myhsok B, Passero K, Zhou J, McGuigan J, Jiang B, Pendergrass SA, Zhang Y, Peissig P, Brilliant M, Sleiman P, ... Ritchie MD, et al. Novel EDGE encoding method enhances ability to identify genetic interactions. Plos Genetics. 17: e1009534. PMID 34086673 DOI: 10.1371/journal.pgen.1009534  1
2021 Li B, Veturi Y, Verma A, Bradford Y, Daar ES, Gulick RM, Riddler SA, Robbins GK, Lennox JL, Haas DW, Ritchie MD. Tissue specificity-aware TWAS (TSA-TWAS) framework identifies novel associations with metabolic, immunologic, and virologic traits in HIV-positive adults. Plos Genetics. 17: e1009464. PMID 33901188 DOI: 10.1371/journal.pgen.1009464  1
2021 Shang N, Khan A, Polubriaginof F, Zanoni F, Mehl K, Fasel D, Drawz PE, Carrol RJ, Denny JC, Hathcock MA, Arruda-Olson AM, Peissig PL, Dart RA, Brilliant MH, Larson EB, ... Ritchie MD, et al. Medical records-based chronic kidney disease phenotype for clinical care and "big data" observational and genetic studies. Npj Digital Medicine. 4: 70. PMID 33850243 DOI: 10.1038/s41746-021-00428-1  1
2021 Georgakis MK, Malik R, Li X, Gill D, Levin MG, Vy HMT, Judy R, Ritchie M, Verma SS, Nadkarni GN, Damrauer SM, Theodoratou E, Dichgans M. Genetically Downregulated Interleukin-6 Signaling Is Associated With a Favorable Cardiometabolic Profile: A Phenome-Wide Association Study. Circulation. 143: 1177-1180. PMID 33720771 DOI: 10.1161/CIRCULATIONAHA.120.052604  1
2021 Liu X, Verma A, Ramage H, Garcia G, Myers RL, Lucas A, Michaelson JJ, Coryell W, Kumar A, Charney A, Kazanietz MG, Rader DJ, Ritchie MD, Berrettini WH, Damoiseaux R, et al. Targeting the Coronavirus Nucleocapsid Protein through GSK-3 Inhibition. Medrxiv : the Preprint Server For Health Sciences. PMID 33655282 DOI: 10.1101/2021.02.17.21251933  1
2021 Kosmicki JA, Horowitz JE, Banerjee N, Lanche R, Marcketta A, Maxwell E, Bai X, Sun D, Backman JD, Sharma D, Kang HM, O'Dushlaine C, Yadav A, Mansfield AJ, Li AH, ... ... Ritchie MD, et al. A catalog of associations between rare coding variants and COVID-19 outcomes. Medrxiv : the Preprint Server For Health Sciences. PMID 33655273 DOI: 10.1101/2020.10.28.20221804  1
2021 Horowitz JE, Kosmicki JA, Damask A, Sharma D, Roberts GHL, Justice AE, Banerjee N, Coignet MV, Yadav A, Leader JB, Marcketta A, Park DS, Lanche R, Maxwell E, Knight SC, ... ... Ritchie MD, et al. Common genetic variants identify targets for COVID-19 and individuals at high risk of severe disease. Medrxiv : the Preprint Server For Health Sciences. PMID 33619501 DOI: 10.1101/2020.12.14.20248176  1
2021 Sun L, Surya S, Le AN, Desai H, Doucette A, Gabriel P, Ritchie MD, Rader D, Maillard I, Bange E, Huang AC, Vonderheide RH, DeMichele A, Verma A, Mamtani R, et al. Rates of COVID-19-Related Outcomes in Cancer Compared With Noncancer Patients. Jnci Cancer Spectrum. 5: pkaa120. PMID 33554040 DOI: 10.1093/jncics/pkaa120  1
2021 Bone WP, Siewert KM, Jha A, Klarin D, Damrauer SM, Chang KM, Tsao PS, Assimes TL, Ritchie MD, Voight BF. Multi-trait association studies discover pleiotropic loci between Alzheimer's disease and cardiometabolic traits. Alzheimer's Research & Therapy. 13: 34. PMID 33541420 DOI: 10.1186/s13195-021-00773-z  0.01
2021 Sun L, Surya S, Goodman NG, Le AN, Kelly G, Owoyemi O, Desai H, Zheng C, DeLuca S, Good ML, Hussain J, Jeffries SD, Kry YR, Kugler EM, Mansour M, ... ... Ritchie M, et al. SARS-CoV-2 seropositivity and seroconversion in patients undergoing active cancer-directed therapy. Medrxiv : the Preprint Server For Health Sciences. PMID 33469597 DOI: 10.1101/2021.01.15.21249810  1
2021 Gu X, Yang H, Sheng X, Ko YA, Qiu C, Park J, Huang S, Kember R, Judy RL, Park J, Damrauer SM, Nadkarni G, Loos RJF, My VTH, Chaudhary K, ... ... Ritchie M, et al. Kidney disease genetic risk variants alter lysosomal beta-mannosidase () expression and disease severity. Science Translational Medicine. 13. PMID 33441424 DOI: 10.1126/scitranslmed.aaz1458  1
2021 Park J, Lucas AM, Zhang X, Chaudhary K, Cho JH, Nadkarni G, Dobbyn A, Chittoor G, Josyula NS, Katz N, Breeyear JH, Ahmadmehrabi S, Drivas TG, Chavali VRM, Fasolino M, ... Ritchie MD, et al. Exome-wide evaluation of rare coding variants using electronic health records identifies new gene-phenotype associations. Nature Medicine. PMID 33432171 DOI: 10.1038/s41591-020-1133-8  1
2021 Li R, Duan R, Zhang X, Lumley T, Pendergrass S, Bauer C, Hakonarson H, Carrell DS, Smoller JW, Wei WQ, Carroll R, Velez Edwards DR, Wiesner G, Sleiman P, Denny JC, ... Ritchie MD, et al. Lossless integration of multiple electronic health records for identifying pleiotropy using summary statistics. Nature Communications. 12: 168. PMID 33420026 DOI: 10.1038/s41467-020-20211-2  1
2021 Rosenthal EA, Crosslin DR, Gordon AS, Carrell DS, Stanaway IB, Larson EB, Grafton J, Wei WQ, Denny JC, Feng QP, Shah AS, Sturm AC, Ritchie MD, Pacheco JA, Hakonarson H, et al. Association between triglycerides, known risk SNVs and conserved rare variation in SLC25A40 in a multi-ancestry cohort. Bmc Medical Genomics. 14: 11. PMID 33407432 DOI: 10.1186/s12920-020-00854-2  1
2020 Levin MG, Judy R, Gill D, Vujkovic M, Verma SS, Bradford Y, Ritchie MD, Hyman MC, Nazarian S, Rader DJ, Voight BF, Damrauer SM. Genetics of height and risk of atrial fibrillation: A Mendelian randomization study. Plos Medicine. 17: e1003288. PMID 33031386 DOI: 10.1371/journal.pmed.1003288  1
2020 Klarin D, Verma SS, Judy R, Dikilitas O, Wolford BN, Paranjpe I, Levin MG, Pan C, Tcheandjieu C, Spin JM, Lynch J, Assimes TL, Nyrønning LÅ, Mattsson E, Edwards TL, ... ... Ritchie M, et al. Genetic Architecture of Abdominal Aortic Aneurysm in the Million Veteran Program. Circulation. PMID 32981348 DOI: 10.1161/CIRCULATIONAHA.120.047544  1
2020 Kember RL, Merikangas AK, Verma SS, Verma A, Judy R, Damrauer SM, Ritchie MD, Rader DJ, Bućan M. Polygenic Risk of Psychiatric Disorders Exhibits Cross-trait Associations in Electronic Health Record Data From European Ancestry Individuals. Biological Psychiatry. PMID 32919613 DOI: 10.1016/J.Biopsych.2020.06.026  1
2020 Leonard MA, Cindi Z, Bradford Y, Bourgi K, Koethe J, Turner M, Norwood J, Woodward B, Erdem H, Basham R, Baker P, Rebeiro PF, Sterling TR, Hulgan T, Daar ES, ... Ritchie MD, et al. Efavirenz Pharmacogenetics and Weight Gain following Switch to Integrase Inhibitor-containing Regimens. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 32829410 DOI: 10.1093/Cid/Ciaa1219  1
2020 Verma SS, Bergmeijer TO, Gong L, Reny JL, Lewis JP, Mitchell BD, Alexopoulos D, Aradi D, Altman RB, Bliden K, Bradford Y, Campo G, Chang K, Cleator JH, Déry JP, ... Ritchie MD, et al. Genome-wide association study of platelet reactivity and cardiovascular response in patients treated with clopidogrel: a study by the International Clopidogrel Pharmacogenomics Consortium (ICPC). Clinical Pharmacology and Therapeutics. PMID 32472697 DOI: 10.1002/Cpt.1911  1
2020 Moore JH, Barnett I, Boland MR, Chen Y, Demiris G, Gonzalez-Hernandez G, Herman DS, Himes BE, Hubbard RA, Kim D, Morris JS, Mowery DL, Ritchie MD, Shen L, Urbanowicz R, et al. Ideas for how informaticians can get involved with COVID-19 research. Biodata Mining. 13: 3. PMID 32419848 DOI: 10.1186/S13040-020-00213-Y  1
2020 Li R, Chen Y, Ritchie MD, Moore JH. Electronic health records and polygenic risk scores for predicting disease risk. Nature Reviews. Genetics. PMID 32235907 DOI: 10.1038/S41576-020-0224-1  1
2020 Amarasinghe SL, Su S, Dong X, Zappia L, Ritchie ME, Gouil Q. Opportunities and challenges in long-read sequencing data analysis. Genome Biology. 21: 30. PMID 32033565 DOI: 10.1186/s13059-020-1935-5  1
2020 Joo YY, Actkins K, Pacheco JA, Basile AO, Carroll R, Crosslin DR, Day F, Denny JC, Velez Edwards DR, Hakonarson H, Harley JB, Hebbring SJ, Ho K, Jarvik GP, Jones M, ... Ritchie MD, et al. A polygenic and phenotypic risk prediction for Polycystic Ovary Syndrome evaluated by Phenome-wide association studies. The Journal of Clinical Endocrinology and Metabolism. PMID 31917831 DOI: 10.1210/Clinem/Dgz326  1
2019 Lucas AM, Palmiero NE, McGuigan J, Passero K, Zhou J, Orie D, Ritchie MD, Hall MA. CLARITE Facilitates the Quality Control and Analysis Process for EWAS of Metabolic-Related Traits. Frontiers in Genetics. 10: 1240. PMID 31921293 DOI: 10.3389/Fgene.2019.01240  1
2019 Pendergrass SA, Buyske S, Jeff JM, Frase A, Dudek S, Bradford Y, Ambite JL, Avery CL, Buzkova P, Deelman E, Fesinmeyer MD, Haiman C, Heiss G, Hindorff LA, Hsu CN, ... Ritchie MD, et al. A phenome-wide association study (PheWAS) in the Population Architecture using Genomics and Epidemiology (PAGE) study reveals potential pleiotropy in African Americans. Plos One. 14: e0226771. PMID 31891604 DOI: 10.1371/Journal.Pone.0226771  1
2019 Damrauer SM, Chaudhary K, Cho JH, Liang LW, Argulian E, Chan L, Dobbyn A, Guerraty MA, Judy R, Kay J, Kember RL, Levin MG, Saha A, Van Vleck T, Verma SS, ... Ritchie M, et al. Association of the V122I Hereditary Transthyretin Amyloidosis Genetic Variant With Heart Failure Among Individuals of African or Hispanic/Latino Ancestry. Jama. 322: 2191-2202. PMID 31821430 DOI: 10.1001/Jama.2019.17935  1
2019 Koay HF, Su S, Amann-Zalcenstein D, Daley SR, Comerford I, Miosge L, Whyte CE, Konstantinov IE, d'Udekem Y, Baldwin T, Hickey PF, Berzins SP, Mak JYW, Sontani Y, Roots CM, ... ... Ritchie ME, et al. A divergent transcriptional landscape underpins the development and functional branching of MAIT cells. Science Immunology. 4. PMID 31757835 DOI: 10.1126/Sciimmunol.Aay6039  1
2019 Schmidt AF, Holmes MV, Preiss D, Swerdlow DI, Denaxas S, Fatemifar G, Faraway R, Finan C, Valentine D, Fairhurst-Hunter Z, Hartwig FP, Horta BL, Hypponen E, Power C, Moldovan M, ... Ritchie MD, et al. Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9. Bmc Cardiovascular Disorders. 19: 240. PMID 31664920 DOI: 10.1186/S12872-019-1187-Z  1
2019 Glessner JT, Li J, Desai A, Palmer M, Kim D, Lucas AM, Chang X, Connolly JJ, Almoguera B, Harley JB, Jarvik GP, Ritchie MD, Sleiman PMA, Roden DM, Crosslin D, et al. CNV Association of Diverse Clinical Phenotypes from eMERGE reveals novel disease biology underlying cardiovascular disease. International Journal of Cardiology. PMID 31447229 DOI: 10.1016/J.Ijcard.2019.07.058  1
2019 Park J, Levin MG, Haggerty CM, Hartzel DN, Judy R, Kember RL, Reza N, Ritchie MD, Owens AT, Damrauer SM, Rader DJ. A genome-first approach to aggregating rare genetic variants in LMNA for association with electronic health record phenotypes. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 31383942 DOI: 10.1038/S41436-019-0625-8  1
2019 Namjou B, Lingren T, Huang Y, Parameswaran S, Cobb BL, Stanaway IB, Connolly JJ, Mentch FD, Benoit B, Niu X, Wei WQ, Carroll RJ, Pacheco JA, Harley ITW, Divanovic S, ... Ritchie MD, et al. GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network. Bmc Medicine. 17: 135. PMID 31311600 DOI: 10.1186/S12916-019-1364-Z  1
2019 Sangkuhl K, Whirl-Carrillo M, Whaley RM, Woon M, Lavertu A, Altman RB, Carter L, Verma A, Ritchie MD, Klein TE. Pharmacogenomics Clinical Annotation Tool (PharmCAT). Clinical Pharmacology and Therapeutics. PMID 31306493 DOI: 10.1002/Cpt.1568  1
2019 Haggerty CM, Damrauer SM, Levin MG, Birtwell D, Carey DJ, Golden AM, Hartzel DN, Hu Y, Judy R, Kelly MA, Kember RL, Kirchner HL, Leader JB, Liang L, McDermott-Roe C, ... Ritchie MD, et al. Genomics-First Evaluation of Heart Disease Associated With Titin-Truncating Variants. Circulation. PMID 31216868 DOI: 10.1161/Circulationaha.119.039573  1
2019 Miller JE, Metpally RP, Person TN, Krishnamurthy S, Dasari VR, Shivakumar M, Lavage DR, Cook AM, Carey DJ, Ritchie MD, Kim D, Gogoi R. Correction to: Systematic characterization of germline variants from the DiscovEHR study endometrial carcinoma population. Bmc Medical Genomics. 12: 65. PMID 31118041 DOI: 10.1186/S12920-019-0523-6  1
2019 Miller JE, Metpally RP, Person TN, Krishnamurthy S, Dasari VR, Shivakumar M, Lavage DR, Cook AM, Carey DJ, Ritchie MD, Kim D, Gogoi R. Systematic characterization of germline variants from the DiscovEHR study endometrial carcinoma population. Bmc Medical Genomics. 12: 59. PMID 31053132 DOI: 10.1186/S12920-019-0504-9  1
2019 Hellwege JN, Stallings S, Torstenson ES, Carroll R, Borthwick KM, Brilliant MH, Crosslin D, Gordon A, Hripcsak G, Jarvik GP, Linneman JG, Devi P, Peissig PL, Sleiman PAM, Hakonarson H, Ritchie MD, et al. Heritability and genome-wide association study of benign prostatic hyperplasia (BPH) in the eMERGE network. Scientific Reports. 9: 6077. PMID 30988330 DOI: 10.1038/S41598-019-42427-Z  1
2019 Li B, Veturi Y, Bradford Y, Verma SS, Verma A, Lucas AM, Haas DW, Ritchie MD. Influence of tissue context on gene prioritization for predicted transcriptome-wide association studies. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 24: 296-307. PMID 30864331  1
2019 Zhang X, Veturi Y, Verma S, Bone W, Verma A, Lucas A, Hebbring S, Denny JC, Stanaway IB, Jarvik GP, Crosslin D, Larson EB, Rasmussen-Torvik L, Pendergrass SA, Smoller JW, ... Ritchie MD, et al. Detecting potential pleiotropy across cardiovascular and neurological diseases using univariate, bivariate, and multivariate methods on 43,870 individuals from the eMERGE network. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 24: 272-283. PMID 30864329  1
2019 Safarova MS, Satterfield BA, Fan X, Austin EE, Ye Z, Bastarache L, Zheng N, Ritchie MD, Borthwick KM, Williams MS, Larson EB, Scrol A, Jarvik GP, Crosslin DR, Leppig K, et al. A phenome-wide association study to discover pleiotropic effects of , , and . Npj Genomic Medicine. 4: 3. PMID 30774981 DOI: 10.1038/S41525-019-0078-7  1
2019 Moore JH, Boland MR, Camara PG, Chervitz H, Gonzalez G, Himes BE, Kim D, Mowery DL, Ritchie MD, Shen L, Urbanowicz RJ, Holmes JH. Preparing next-generation scientists for biomedical big data: artificial intelligence approaches. Personalized Medicine. PMID 30760118 DOI: 10.2217/Pme-2018-0145  1
2019 Zhang X, Basile AO, Pendergrass SA, Ritchie MD. Real world scenarios in rare variant association analysis: the impact of imbalance and sample size on the power in silico. Bmc Bioinformatics. 20: 46. PMID 30669967 DOI: 10.1186/S12859-018-2591-6  1
2018 Verma A, Bang L, Miller JE, Zhang Y, Lee MTM, Zhang Y, Byrska-Bishop M, Carey DJ, Ritchie MD, Pendergrass SA, Kim D. Human-Disease Phenotype Map Derived from PheWAS across 38,682 Individuals. American Journal of Human Genetics. PMID 30598166 DOI: 10.1016/J.Ajhg.2018.11.006  1
2018 Mosley JD, Benson MD, Smith JG, Melander O, Ngo D, Shaffer CM, Ferguson JF, Herzig MS, McCarty CA, Chute CG, Jarvik GP, Gordon AS, Palmer MR, Crosslin DR, Larson EB, ... Ritchie MD, et al. Probing the Virtual Proteome to Identify Novel Disease Biomarkers. Circulation. 138: 2469-2481. PMID 30571344 DOI: 10.1161/Circulationaha.118.036063  1
2018 Verma SS, Josyula N, Verma A, Zhang X, Veturi Y, Dewey FE, Hartzel DN, Lavage DR, Leader J, Ritchie MD, Pendergrass SA. Author Correction: Rare variants in drug target genes contributing to complex diseases, phenome-wide. Scientific Reports. 8: 15911. PMID 30353015 DOI: 10.1038/S41598-018-27936-7  1
2018 Stanaway IB, Hall TO, Rosenthal EA, Palmer M, Naranbhai V, Knevel R, Namjou-Khales B, Carroll RJ, Kiryluk K, Gordon AS, Linder J, Howell KM, Mapes BM, Lin FTJ, Joo YY, ... Ritchie MD, et al. The eMERGE genotype set of 83,717 subjects imputed to ~40 million variants genome wide and association with the herpes zoster medical record phenotype. Genetic Epidemiology. PMID 30298529 DOI: 10.1002/Gepi.22167  1
2018 Mosley JD, Feng Q, Wells QS, Van Driest SL, Shaffer CM, Edwards TL, Bastarache L, Wei WQ, Davis LK, McCarty CA, Thompson W, Chute CG, Jarvik GP, Gordon AS, Palmer MR, ... Ritchie MD, et al. A study paradigm integrating prospective epidemiologic cohorts and electronic health records to identify disease biomarkers. Nature Communications. 9: 3522. PMID 30166544 DOI: 10.1038/S41467-018-05624-4  1
2018 van Setten J, Brody JA, Jamshidi Y, Swenson BR, Butler AM, Campbell H, Del Greco FM, Evans DS, Gibson Q, Gudbjartsson DF, Kerr KF, Krijthe BP, Lyytikäinen LP, Müller C, Müller-Nurasyid M, ... Ritchie MD, et al. PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity. Nature Communications. 9: 2904. PMID 30046033 DOI: 10.1038/S41467-018-04766-9  1
2018 Haas DW, Bradford Y, Verma A, Verma SS, Eron JJ, Gulick RM, Riddler SA, Sax PE, Daar ES, Morse GD, Acosta EP, Ritchie MD. Brain neurotransmitter transporter/receptor genomics and efavirenz central nervous system adverse events. Pharmacogenetics and Genomics. PMID 29847509 DOI: 10.1097/Fpc.0000000000000341  1
2018 Li R, Kim D, Wheeler HE, Dudek SM, Dolan ME, Ritchie MD. Integration of genetic and functional genomics data to uncover chemotherapeutic induced cytotoxicity. The Pharmacogenomics Journal. PMID 29795408 DOI: 10.1038/S41397-018-0024-6  1
2018 Verma SS, Lucas A, Zhang X, Veturi Y, Dudek S, Li B, Li R, Urbanowicz R, Moore JH, Kim D, Ritchie MD. Collective feature selection to identify crucial epistatic variants. Biodata Mining. 11: 5. PMID 29713383 DOI: 10.1186/S13040-018-0168-6  1
2018 Wei WQ, Li X, Feng Q, Kubo M, Kullo IJ, Peissig PL, Karlson EW, Jarvik GP, Lee MTM, Shang N, Larson EA, Edwards T, Shaffer C, Mosley JD, Maeda S, ... Ritchie M, et al. Variants are Associated with Residual Cardiovascular Risk in Patients Receiving Statins. Circulation. PMID 29703846 DOI: 10.1161/Circulationaha.117.031356  1
2018 Verma A, Bradford Y, Dudek S, Lucas AM, Verma SS, Pendergrass SA, Ritchie MD. A simulation study investigating power estimates in phenome-wide association studies. Bmc Bioinformatics. 19: 120. PMID 29618318 DOI: 10.1186/S12859-018-2135-0  1
2018 Verma A, Lucas A, Verma SS, Zhang Y, Josyula N, Khan A, Hartzel DN, Lavage DR, Leader J, Ritchie MD, Pendergrass SA. PheWAS and Beyond: The Landscape of Associations with Medical Diagnoses and Clinical Measures across 38,662 Individuals from Geisinger. American Journal of Human Genetics. PMID 29606303 DOI: 10.1016/J.Ajhg.2018.02.017  1
2018 Verma SS, Josyula N, Verma A, Zhang X, Veturi Y, Dewey FE, Hartzel DN, Lavage DR, Leader J, Ritchie MD, Pendergrass SA. Rare variants in drug target genes contributing to complex diseases, phenome-wide. Scientific Reports. 8: 4624. PMID 29545597 DOI: 10.1038/S41598-018-22834-4  1
2018 Volpi S, Bult C, Chisholm RL, Deverka PA, Ginsburg GS, Jacob HJ, Kasapi M, McLeod HL, Roden DM, Williams MS, Green ED, Lyman Rodriguez L, Aronson S, Cavallari LH, Denny JC, ... Ritchie MD, et al. Research directions in the clinical implementation of pharmacogenomics - An Overview of US programs and projects. Clinical Pharmacology and Therapeutics. PMID 29460415 DOI: 10.1002/Cpt.1048  1
2018 Li B, Verma SS, Veturi YC, Verma A, Bradford Y, Haas DW, Ritchie MD. Evaluation of PrediXcan for prioritizing GWAS associations and predicting gene expression. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 23: 448-459. PMID 29218904  1
2018 Basile AO, Byrska-Bishop M, Wallace J, Frase AT, Ritchie MD. Novel features and enhancements in BioBin, a tool for the biologically inspired binning and association analysis of rare variants. Bioinformatics (Oxford, England). 34: 527-529. PMID 28968757 DOI: 10.1093/Bioinformatics/Btx559  1
2017 Verma A, Ritchie MD. Current Scope and Challenges in Phenome-Wide Association Studies. Current Epidemiology Reports. 4: 321-329. PMID 29545989 DOI: 10.1007/S40471-017-0127-7  1
2017 Hall MA, Wallace J, Lucas A, Kim D, Basile AO, Verma SS, McCarty CA, Brilliant MH, Peissig PL, Kitchner TE, Verma A, Pendergrass SA, Dudek SM, Moore JH, Ritchie MD. PLATO software provides analytic framework for investigating complexity beyond genome-wide association studies. Nature Communications. 8: 1167. PMID 29079728 DOI: 10.1038/S41467-017-00802-2  1
2017 McAllister K, Mechanic LE, Amos C, Aschard H, Blair IA, Chatterjee N, Conti D, Gauderman WJ, Hsu L, Hutter CM, Jankowska MM, Kerr J, Kraft P, Montgomery SB, Mukherjee B, ... Ritchie MD, et al. Current Challenges and New Opportunities for Gene-Environment Interaction Studies of Complex Diseases. American Journal of Epidemiology. 186: 753-761. PMID 28978193 DOI: 10.1093/Aje/Kwx227  1
2017 Mechanic LE, Lindström S, Daily KM, Sieberts SK, Amos CI, Chen HS, Cox NJ, Dathe M, Feuer EJ, Guertin MJ, Hoffman J, Liu Y, Moore JH, Myers CL, Ritchie MD, et al. Up For A Challenge (U4C): Stimulating innovation in breast cancer genetic epidemiology. Plos Genetics. 13: e1006945. PMID 28957327 DOI: 10.1371/Journal.Pgen.1006945  1
2017 Holzinger ER, Verma SS, Moore CB, Hall M, De R, Gilbert-Diamond D, Lanktree MB, Pankratz N, Amuzu A, Burt A, Dale C, Dudek S, Furlong CE, Gaunt TR, Kim DS, ... Ritchie MD, et al. Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals. Biodata Mining. 10: 25. PMID 28770004 DOI: 10.1186/S13040-017-0145-5  1
2017 Li R, Kim D, Ritchie MD. Methods to analyze big data in pharmacogenomics research. Pharmacogenomics. PMID 28612644 DOI: 10.2217/Pgs-2016-0152  1
2017 Kim D, Basile AO, Bang L, Horgusluoglu E, Lee S, Ritchie MD, Saykin AJ, Nho K. Knowledge-driven binning approach for rare variant association analysis: application to neuroimaging biomarkers in Alzheimer's disease. Bmc Medical Informatics and Decision Making. 17: 61. PMID 28539126 DOI: 10.1186/S12911-017-0454-0  1
2017 Rasmussen-Torvik LJ, Almoguera B, Doheny KF, Freimuth RR, Gordon AS, Hakonarson H, Hawkins JB, Husami A, Ivacic L, Kullo IJ, Linderman MD, Manolio TA, Obeng AO, Pellegrino R, Prows CA, Ritchie MD, et al. Concordance between Research Sequencing and Clinical Pharmacogenetic Genotyping in the eMERGE-PGx Study. The Journal of Molecular Diagnostics : Jmd. PMID 28502727 DOI: 10.1016/J.Jmoldx.2017.04.002  1
2017 Haggerty CM, James CA, Calkins H, Tichnell C, Leader JB, Hartzel DN, Nevius CD, Pendergrass SA, Person TN, Schwartz M, Ritchie MD, Carey DJ, Ledbetter DH, Williams MS, Dewey FE, et al. Electronic health record phenotype in subjects with genetic variants associated with arrhythmogenic right ventricular cardiomyopathy: a study of 30,716 subjects with exome sequencing. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 28471438 DOI: 10.1038/Gim.2017.40  1
2017 Kim D, Volk H, Girirajan S, Pendergrass S, Hall MA, Verma SS, Schmidt RJ, Hansen RL, Ghosh D, Ludena-Rodriguez Y, Kim K, Ritchie MD, Hertz-Picciotto I, Selleck SB. The joint effect of air pollution exposure and copy number variation on risk for autism. Autism Research : Official Journal of the International Society For Autism Research. PMID 28448694 DOI: 10.1002/Aur.1799  1
2017 Fernández-Rhodes L, Gong J, Haessler J, Franceschini N, Graff M, Nishimura KK, Wang Y, Highland HM, Yoneyama S, Bush WS, Goodloe R, Ritchie MD, Crawford D, Gross M, Fornage M, et al. Trans-ethnic fine-mapping of genetic loci for body mass index in the diverse ancestral populations of the Population Architecture using Genomics and Epidemiology (PAGE) Study reveals evidence for multiple signals at established loci. Human Genetics. PMID 28391526 DOI: 10.1007/S00439-017-1787-6  1
2017 Dumitrescu L, Ritchie MD, Denny JC, El Rouby NM, McDonough CW, Bradford Y, Ramirez AH, Bielinski SJ, Basford MA, Chai HS, Peissig P, Carrell D, Pathak J, Rasmussen LV, Wang X, et al. Genome-wide study of resistant hypertension identified from electronic health records. Plos One. 12: e0171745. PMID 28222112 DOI: 10.1371/Journal.Pone.0171745  1
2017 Heit JA, Armasu SM, McCauley BM, Kullo IJ, Sicotte H, Pathak J, Chute CG, Gottesman O, Bottinger EP, Denny JC, Roden DM, Li R, Ritchie MD, de Andrade M. Identification of unique venous thromboembolism-susceptibility variants in African-Americans. Thrombosis and Haemostasis. PMID 28203683 DOI: 10.1160/Th16-08-0652  1
2017 Verma A, Bradford Y, Verma SS, Pendergrass SA, Daar ES, Venuto C, Morse GD, Ritchie MD, Haas DW. Multiphenotype association study of patients randomized to initiate antiretroviral regimens in AIDS Clinical Trials Group protocol A5202. Pharmacogenetics and Genomics. PMID 28099408 DOI: 10.1097/Fpc.0000000000000263  1
2016 Kim D, Li R, Lucas A, Verma SS, Dudek SM, Ritchie MD. Using knowledge-driven genomic interactions for multi-omics data analysis: metadimensional models for predicting clinical outcomes in ovarian carcinoma. Journal of the American Medical Informatics Association : Jamia. PMID 28040685 DOI: 10.1093/Jamia/Ocw165  1
2016 Dewey FE, Murray MF, Overton JD, Habegger L, Leader JB, Fetterolf SN, O'Dushlaine C, Van Hout CV, Staples J, Gonzaga-Jauregui C, Metpally R, Pendergrass SA, Giovanni MA, Kirchner HL, Balasubramanian S, ... Ritchie MD, et al. Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study. Science (New York, N.Y.). 354. PMID 28008009 DOI: 10.1126/Science.Aaf6814  1
2016 Schmidt AF, Swerdlow DI, Holmes MV, Patel RS, Fairhurst-Hunter Z, Lyall DM, Hartwig FP, Horta BL, Hyppönen E, Power C, Moldovan M, van Iperen E, Hovingh GK, Demuth I, Norman K, ... Ritchie MD, et al. PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study. The Lancet. Diabetes & Endocrinology. PMID 27908689 DOI: 10.1016/S2213-8587(16)30396-5  1
2016 Jones GT, Tromp G, Kuivaniemi H, Gretarsdottir S, Baas AF, Giusti B, Strauss E, van 't Hof FN, Webb T, Erdman R, Ritchie MD, Elmore JR, Verma A, Pendergrass S, Kullo IJ, et al. Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci. Circulation Research. PMID 27899403 DOI: 10.1161/Circresaha.116.308765  1
2016 Verma SS, Lucas AM, Lavage DR, Leader JB, Metpally R, Krishnamurthy S, Dewey F, Borecki I, Lopez A, Overton J, Penn J, Reid J, Pendergrass SA, Breitwieser G, Ritchie MD. IDENTIFYING GENETIC ASSOCIATIONS WITH VARIABILITY IN METABOLIC HEALTH AND BLOOD COUNT LABORATORY VALUES: DIVING INTO THE QUANTITATIVE TRAITS BY LEVERAGING LONGITUDINAL DATA FROM AN EHR. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 22: 533-544. PMID 27897004  1
2016 Yoneyama S, Yao J, Guo X, Fernandez-Rhodes L, Lim U, Boston J, Buzková P, Carlson CS, Cheng I, Cochran B, Cooper R, Ehret G, Fornage M, Gong J, Gross M, ... Ritchie MD, et al. Generalization and fine mapping of European ancestry-based central adiposity variants in African ancestry populations. International Journal of Obesity (2005). PMID 27867202 DOI: 10.1038/Ijo.2016.207  1
2016 De R, Verma SS, Holzinger E, Hall M, Burt A, Carrell DS, Crosslin DR, Jarvik GP, Kuivaniemi H, Kullo IJ, Lange LA, Lanktree MB, Larson EB, North KE, Reiner AP, ... Ritchie MD, et al. Identifying gene-gene interactions that are highly associated with four quantitative lipid traits across multiple cohorts. Human Genetics. PMID 27848076 DOI: 10.1007/S00439-016-1738-7  1
2016 Verma SS, Cooke Bailey JN, Lucas A, Bradford Y, Linneman JG, Hauser MA, Pasquale LR, Peissig PL, Brilliant MH, McCarty CA, Haines JL, Wiggs JL, Vrabec TR, Tromp G, Ritchie MD, et al. Epistatic Gene-Based Interaction Analyses for Glaucoma in eMERGE and NEIGHBOR Consortium. Plos Genetics. 12: e1006186. PMID 27623284 DOI: 10.1371/Journal.Pgen.1006186  1
2016 Moore CC, Basile AO, Wallace JR, Frase AT, Ritchie MD. A biologically informed method for detecting rare variant associations. Biodata Mining. 9: 27. PMID 27582876 DOI: 10.1186/S13040-016-0107-3  1
2016 Verma A, Verma SS, Pendergrass SA, Crawford DC, Crosslin DR, Kuivaniemi H, Bush WS, Bradford Y, Kullo I, Bielinski SJ, Li R, Denny JC, Peissig P, Hebbring S, De Andrade M, Ritchie MD, et al. eMERGE Phenome-Wide Association Study (PheWAS) identifies clinical associations and pleiotropy for stop-gain variants. Bmc Medical Genomics. 9: 32. PMID 27535653 DOI: 10.1186/S12920-016-0191-8  1
2016 Verma A, Basile AO, Bradford Y, Kuivaniemi H, Tromp G, Carey D, Gerhard GS, Crowe JE, Ritchie MD, Pendergrass SA. Phenome-Wide Association Study to Explore Relationships between Immune System Related Genetic Loci and Complex Traits and Diseases. Plos One. 11: e0160573. PMID 27508393 DOI: 10.1371/Journal.Pone.0160573  1
2016 van 't Hof FN, Ruigrok YM, Lee CH, Ripke S, Anderson G, de Andrade M, Baas AF, Blankensteijn JD, Böttinger EP, Bown MJ, Broderick J, Bijlenga P, Carrell DS, Crawford DC, Crosslin DR, ... Ritchie MD, et al. Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms. Journal of the American Heart Association. 5. PMID 27418160 DOI: 10.1161/Jaha.115.002603  1
2016 Hall MA, Moore JH, Ritchie MD. Embracing Complex Associations in Common Traits: Critical Considerations for Precision Medicine. Trends in Genetics : Tig. PMID 27392675 DOI: 10.1016/J.Tig.2016.06.001  1
2016 Oetjens MT, Bush WS, Denny JC, Birdwell K, Kodaman N, Verma A, Dilks HH, Pendergrass SA, Ritchie MD, Crawford DC. Evidence for extensive pleiotropy among pharmacogenes. Pharmacogenomics. 0. PMID 27249515 DOI: 10.2217/Pgs-2015-0007  1
2016 Li R, Dudek SM, Kim D, Hall MA, Bradford Y, Peissig PL, Brilliant MH, Linneman JG, McCarty CA, Bao L, Ritchie MD. Identification of genetic interaction networks via an evolutionary algorithm evolved Bayesian network. Biodata Mining. 9: 18. PMID 27168765 DOI: 10.1186/S13040-016-0094-4  1
2016 Butkiewicz M, Cooke Bailey JN, Frase A, Dudek S, Yaspan BL, Ritchie MD, Pendergrass SA, Haines JL. Pathway analysis by randomization incorporating structure-PARIS: an update. Bioinformatics (Oxford, England). PMID 27153576 DOI: 10.1093/Bioinformatics/Btw130  1
2016 Ritchie MG. JEB Editorial 2016. Journal of Evolutionary Biology. 29: 472. PMID 26957050 DOI: 10.1111/Jeb.12841  1
2016 Dewey FE, Gusarova V, O'Dushlaine C, Gottesman O, Trejos J, Hunt C, Van Hout CV, Habegger L, Buckler D, Lai KV, Leader JB, Murray MF, Ritchie MD, Kirchner HL, Ledbetter DH, et al. Inactivating Variants in ANGPTL4 and Risk of Coronary Artery Disease. The New England Journal of Medicine. PMID 26933753 DOI: 10.1056/Nejmoa1510926  1
2016 Simonti CN, Vernot B, Bastarache L, Bottinger E, Carrell DS, Chisholm RL, Crosslin DR, Hebbring SJ, Jarvik GP, Kullo IJ, Li R, Pathak J, Ritchie MD, Roden DM, Verma SS, et al. The phenotypic legacy of admixture between modern humans and Neandertals. Science (New York, N.Y.). 351: 737-41. PMID 26912863 DOI: 10.1126/Science.Aad2149  1
2016 Bush WS, Crosslin DR, Obeng AO, Wallace J, Almoguera B, Basford MA, Bielinski SJ, Carrell DS, Connolly JJ, Crawford D, Doheny KF, Gallego CJ, Gordon AS, Keating B, Kirby J, ... Ritchie MD, et al. Genetic Variation among 82 Pharmacogenes: the PGRN-Seq data from the eMERGE Network. Clinical Pharmacology and Therapeutics. PMID 26857349 DOI: 10.1002/Cpt.350  1
2016 Brown NL, Peacock MM, Ritchie ME. Genetic variation and population structure in a threatened species, the Utah prairie dog Cynomys parvidens: the use of genetic data to inform conservation actions. Ecology and Evolution. 6: 426-46. PMID 26843928 DOI: 10.1002/Ece3.1874  1
2016 Hohman TJ, Bush WS, Jiang L, Brown-Gentry KD, Torstenson ES, Dudek SM, Mukherjee S, Naj A, Kunkle BW, Ritchie MD, Martin ER, Schellenberg GD, Mayeux R, Farrer LA, Pericak-Vance MA, et al. Discovery of gene-gene interactions across multiple independent data sets of late onset Alzheimer disease from the Alzheimer Disease Genetics Consortium. Neurobiology of Aging. 38: 141-50. PMID 26827652 DOI: 10.1016/J.Neurobiolaging.2015.10.031  1
2016 Siefert A, Ritchie ME. Intraspecific trait variation drives functional responses of old-field plant communities to nutrient enrichment. Oecologia. PMID 26826004 DOI: 10.1007/S00442-016-3563-Z  1
2016 Kim D, Lucas A, Glessner J, Verma SS, Bradford Y, Li R, Frase AT, Hakonarson H, Peissig P, Brilliant M, Ritchie MD. BIOFILTER AS A FUNCTIONAL ANNOTATION PIPELINE FOR COMMON AND RARE COPY NUMBER BURDEN. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 21: 357-68. PMID 26776200  1
2016 Basile AO, Wallace JR, Peissig P, McCarty CA, Brilliant M, Ritchie MD. KNOWLEDGE DRIVEN BINNING AND PHEWAS ANALYSIS IN MARSHFIELD PERSONALIZED MEDICINE RESEARCH PROJECT USING BIOBIN. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 21: 249-60. PMID 26776191  1
2016 Verma A, Leader JB, Verma SS, Frase A, Wallace J, Dudek S, Lavage DR, VAN Hout CV, Dewey FE, Penn J, Lopez A, Overton JD, Carey DJ, Ledbetter DH, Kirchner HL, Ritchie MD, et al. INTEGRATING CLINICAL LABORATORY MEASURES AND ICD-9 CODE DIAGNOSES IN PHENOME-WIDE ASSOCIATION STUDIES. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 21: 168-79. PMID 26776183  1
2016 Verma SS, Frase AT, Verma A, Pendergrass SA, Mahony S, Haas DW, Ritchie MD. PHENOME-WIDE INTERACTION STUDY (PheWIS) IN AIDS CLINICAL TRIALS GROUP DATA (ACTG). Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 21: 57-68. PMID 26776173  1
2016 Bailey JN, Loomis SJ, Kang JH, Allingham RR, Gharahkhani P, Khor CC, Burdon KP, Aschard H, Chasman DI, Igo RP, Hysi PG, Glastonbury CA, Ashley-Koch A, Brilliant M, Brown AA, ... Ritchie M, et al. Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma. Nature Genetics. PMID 26752265 DOI: 10.1038/Ng.3482  1
2016 Van Driest SL, Wells QS, Stallings S, Bush WS, Gordon A, Nickerson DA, Kim JH, Crosslin DR, Jarvik GP, Carrell DS, Ralston JD, Larson EB, Bielinski SJ, Olson JE, Ye Z, ... Ritchie MD, et al. Association of Arrhythmia-Related Genetic Variants With Phenotypes Documented in Electronic Medical Records. Jama. 315: 47-57. PMID 26746457 DOI: 10.1001/Jama.2015.17701  1
2016 Watts S, Rosenberg L, Bocquet S, Ritchie M. Doppler spectra of medium grazing angle sea clutter; part 2: Model assessment and simulation Iet Radar, Sonar and Navigation. 10: 32-42. DOI: 10.1049/iet-rsn.2015.0149  1
2016 Watts S, Rosenberg L, Bocquet S, Ritchie M. Doppler spectra of medium grazing angle sea clutter; part 1: Characterisation Iet Radar, Sonar and Navigation. 10: 24-31. DOI: 10.1049/iet-rsn.2015.0148  1
2016 Fioranelli F, Ritchie M, Balleri A, Griffiths H. Experimental analysis of multistatic wind turbine radar clutter statistics Electronics Letters. 52: 226-228. DOI: 10.1049/e1.2015.3907  1
2016 Ritchie MB, Forth AE. Without concern: Predicting personal-moral transgressions from psychopathy and gender Personality and Individual Differences. 94: 247-252. DOI: 10.1016/J.Paid.2016.01.041  1
2016 Liu R, Chen K, Jansz N, Blewitt ME, Ritchie ME. Transcriptional profiling of the epigenetic regulator Smchd1 Genomics Data. 7: 144-147. DOI: 10.1016/j.gdata.2015.12.027  1
2016 Ala-Honkola O, Ritchie MG, Veltsos P. Postmating-prezygotic isolation between two allopatric populations of Drosophila montana: Fertilisation success differs under sperm competition Ecology and Evolution. DOI: 10.1002/ece3.1995  1
2015 De R, Verma SS, Drenos F, Holzinger ER, Holmes MV, Hall MA, Crosslin DR, Carrell DS, Hakonarson H, Jarvik G, Larson E, Pacheco JA, Rasmussen-Torvik LJ, Moore CB, Asselbergs FW, ... ... Ritchie MD, et al. Identifying gene-gene interactions that are highly associated with Body Mass Index using Quantitative Multifactor Dimensionality Reduction (QMDR). Biodata Mining. 8: 41. PMID 26674805 DOI: 10.1186/S13040-015-0074-0  1
2015 Ritchie MK, Johnson LC, Clodfelter JE, Pemble CW, Fulp BE, Furdui CM, Kridel SJ, Lowther WT. Crystal Structure and Substrate Specificity of Human Thioesterase 2: Insights into the Molecular Basis for the Modulation of Fatty Acid Synthase. The Journal of Biological Chemistry. PMID 26663084 DOI: 10.1074/Jbc.M115.702597  1
2015 Tan C, Ritchie M, Alldred J, Daneman N. Validating hospital antibiotic purchasing data as a metric of inpatient antibiotic use. The Journal of Antimicrobial Chemotherapy. PMID 26546668 DOI: 10.1093/jac/dkv373  1
2015 Cook N, Trivedi U, Pannebakker BA, Blaxter M, Ritchie MG, Tauber E, Sneddon T, Shuker DM. Oviposition but Not Sex Allocation Is Associated with Transcriptomic Changes in Females of the Parasitoid Wasp Nasonia vitripennis. G3 (Bethesda, Md.). PMID 26511500 DOI: 10.1534/G3.115.021220  1
2015 Holik AZ, Galvis LA, Lun AT, Ritchie ME, Asselin-Labat ML. Transcriptome and H3K27 tri-methylation profiling of Ezh2-deficient lung epithelium. Genomics Data. 5: 346-51. PMID 26484284 DOI: 10.1016/j.gdata.2015.07.006  1
2015 Keating BJ, Setten Jv, Jacobson PA, Holmes MV, Verma SS, Chandrupatla HR, Nair N, Gao H, Li YR, Chang B, Wong C, Phillips R, Cole BS, Mukhtar E, Zhang W, ... Ritchie MD, et al. Design and Implementation of the International Genetics and Translational Research in Transplantation Network Transplantation. 99: 2401-2412. PMID 26479416 DOI: 10.1097/Tp.0000000000000913  1
2015 Cunningham CB, Ji L, Wiberg RA, Shelton J, McKinney EC, Parker DJ, Meagher RB, Benowitz KM, Roy-Zokan EM, Ritchie MG, Brown SJ, Schmitz RJ, Moore AJ. The genome and methylome of a beetle with complex social behavior, Nicrophorus vespilloides (Coleoptera: Silphidae). Genome Biology and Evolution. PMID 26454014 DOI: 10.1093/Gbe/Evv194  1
2015 Li YR, van Setten J, Verma SS, Lu Y, Holmes MV, Gao H, Lek M, Nair N, Chandrupatla H, Chang B, Karczewski KJ, Wong C, Mohebnasab M, Mukhtar E, Phillips R, ... Ritchie MD, et al. Concept and design of a genome-wide association genotyping array tailored for transplantation-specific studies. Genome Medicine. 7: 90. PMID 26423053 DOI: 10.1186/S13073-015-0211-X  1
2015 Parker DJ, Cunningham CB, Walling CA, Stamper CE, Head ML, Roy-Zokan EM, McKinney EC, Ritchie MG, Moore AJ. Transcriptomes of parents identify parenting strategies and sexual conflict in a subsocial beetle. Nature Communications. 6: 8449. PMID 26416581 DOI: 10.1038/Ncomms9449  1
2015 Namjou B, Marsolo K, Lingren T, Ritchie MD, Verma SS, Cobb BL, Perry C, Kitchner TE, Brilliant MH, Peissig PL, Borthwick KM, Williams MS, Grafton J, Jarvik GP, Holm IA, et al. A GWAS Study on Liver Function Test Using eMERGE Network Participants. Plos One. 10: e0138677. PMID 26413716 DOI: 10.1371/Journal.Pone.0138677  1
2015 Gallego CJ, Burt A, Sundaresan AS, Ye Z, Shaw C, Crosslin DR, Crane PK, Fullerton SM, Hansen K, Carrell D, Kuivaniemi H, Derr K, de Andrade M, McCarty CA, Kitchner TE, ... Ritchie M, et al. Penetrance of Hemochromatosis in HFE Genotypes Resulting in p.Cys282Tyr and p.[Cys282Tyr];[His63Asp] in the eMERGE Network. American Journal of Human Genetics. PMID 26365338 DOI: 10.1016/J.Ajhg.2015.08.008  1
2015 Ritchie M, Kelly LJ, Moss J, Paul J, Shaw R. Exploring attitudes towards a randomised controlled trial of venous access devices - a nested pre-trial qualitative study. The Journal of Vascular Access. 16: 407-12. PMID 26349872 DOI: 10.5301/jva.5000447  1
2015 Crosslin DR, Robertson PD, Carrell DS, Gordon AS, Hanna DS, Burt A, Fullerton SM, Scrol A, Ralston J, Leppig K, Hartzler A, Baldwin E, Andrade Md, Kullo IJ, Tromp G, ... Ritchie MD, et al. Prospective participant selection and ranking to maximize actionable pharmacogenetic variants and discovery in the eMERGE Network. Genome Medicine. 7: 67. PMID 26221186 DOI: 10.1186/S13073-015-0181-Z  1
2015 Crawford DC, Goodloe R, Farber-Eger E, Boston J, Pendergrass SA, Haines JL, Ritchie MD, Bush WS. Leveraging Epidemiologic and Clinical Collections for Genomic Studies of Complex Traits. Human Heredity. 79: 137-46. PMID 26201699 DOI: 10.1159/000381805  1
2015 Pendergrass SA, Verma A, Okula A, Hall MA, Crawford DC, Ritchie MD. Phenome-Wide Association Studies: Embracing Complexity for Discovery. Human Heredity. 79: 111-23. PMID 26201697 DOI: 10.1159/000381851  1
2015 Veltsos P, Gregson E, Morrissey B, Slate J, Hoikkala A, Butlin RK, Ritchie MG. The genetic architecture of sexually selected traits in two natural populations of Drosophila montana. Heredity. 115: 565-72. PMID 26198076 DOI: 10.1038/Hdy.2015.63  1
2015 Macnaught G, Ananthakrishnan G, Hinksman L, Yadavali R, Bryden F, Lassman S, Ritchie M, Gallacher K, Hay C, Moss JG. Can (1)H MR Spectroscopy be Used to Assess the Success of Uterine Artery Embolisation? Cardiovascular and Interventional Radiology. PMID 26183465 DOI: 10.1007/s00270-015-1179-z  1
2015 Mosley JD, Shaffer CM, Van Driest SL, Weeke PE, Wells QS, Karnes JH, Velez Edwards DR, Wei WQ, Teixeira PL, Bastarache L, Crawford DC, Li R, Manolio TA, Bottinger EP, McCarty CA, ... Ritchie MD, et al. A genome-wide association study identifies variants in KCNIP4 associated with ACE inhibitor-induced cough. The Pharmacogenomics Journal. PMID 26169577 DOI: 10.1038/Tpj.2015.51  1
2015 Pendergrass SA, Ritchie MD. Phenome-Wide Association Studies: Leveraging Comprehensive Phenotypic and Genotypic Data for Discovery. Current Genetic Medicine Reports. 3: 92-100. PMID 26146598 DOI: 10.1007/S40142-015-0067-9  1
2015 Chen K, Hu J, Moore DL, Liu R, Kessans SA, Breslin K, Lucet IS, Keniry A, Leong HS, Parish CL, Hilton DJ, Lemmers RJ, van der Maarel SM, Czabotar PE, Dobson RC, Ritchie ME, et al. Genome-wide binding and mechanistic analyses of Smchd1-mediated epigenetic regulation. Proceedings of the National Academy of Sciences of the United States of America. PMID 26091879 DOI: 10.1073/pnas.1504232112  1
2015 Kim D, Li R, Dudek SM, Ritchie MD. Predicting censored survival data based on the interactions between meta-dimensional omics data in breast cancer. Journal of Biomedical Informatics. PMID 26048077 DOI: 10.1016/J.Jbi.2015.05.019  1
2015 Hoskins JL, Ritchie MG, Bailey NW. A test of genetic models for the evolutionary maintenance of same-sex sexual behaviour. Proceedings. Biological Sciences / the Royal Society. 282. PMID 26019160 DOI: 10.1098/Rspb.2015.0429  1
2015 Vigoder FM, Souza NA, Brazil RP, Bruno RV, Costa PL, Ritchie MG, Klaczko LB, Peixoto AA. Phenotypic differentiation in love song traits among sibling species of the Lutzomyia longipalpis complex in Brazil. Parasites & Vectors. 8: 290. PMID 26017472 DOI: 10.1186/S13071-015-0900-8  1
2015 Hall MA, Verma SS, Wallace J, Lucas A, Berg RL, Connolly J, Crawford DC, Crosslin DR, de Andrade M, Doheny KF, Haines JL, Harley JB, Jarvik GP, Kitchner T, Kuivaniemi H, ... Ritchie MD, et al. Biology-Driven Gene-Gene Interaction Analysis of Age-Related Cataract in the eMERGE Network. Genetic Epidemiology. 39: 376-84. PMID 25982363 DOI: 10.1002/Gepi.21902  1
2015 Liu R, Holik AZ, Su S, Jansz N, Chen K, Leong HS, Blewitt ME, Asselin-Labat ML, Smyth GK, Ritchie ME. Why weight? Modelling sample and observational level variability improves power in RNA-seq analyses. Nucleic Acids Research. PMID 25925576 DOI: 10.1093/nar/gkv412  1
2015 Ritchie M, Yeap BB. Thyroid hormone: Influences on mood and cognition in adults. Maturitas. 81: 266-275. PMID 25896972 DOI: 10.1016/j.maturitas.2015.03.016  1
2015 Ritchie M, Berthouze L, Kiss IZ. Beyond clustering: mean-field dynamics on networks with arbitrary subgraph composition. Journal of Mathematical Biology. PMID 25893260 DOI: 10.1007/s00285-015-0884-1  1
2015 Moore CB, Verma A, Pendergrass S, Verma SS, Johnson DH, Daar ES, Gulick RM, Haubrich R, Robbins GK, Ritchie MD, Haas DW. Phenome-wide Association Study Relating Pretreatment Laboratory Parameters With Human Genetic Variants in AIDS Clinical Trials Group Protocols. Open Forum Infectious Diseases. 2: ofu113. PMID 25884002 DOI: 10.1093/Ofid/Ofu113  1
2015 Sheridan JM, Ritchie ME, Best SA, Jiang K, Beck TJ, Vaillant F, Liu K, Dickins RA, Smyth GK, Lindeman GJ, Visvader JE. A pooled shRNA screen for regulators of primary mammary stem and progenitor cells identifies roles for Asap1 and Prox1. Bmc Cancer. 15: 221. PMID 25879659 DOI: 10.1186/S12885-015-1187-Z  1
2015 Tyukmaeva VI, Veltsos P, Slate J, Gregson E, Kauranen H, Kankare M, Ritchie MG, Butlin RK, Hoikkala A. Localization of quantitative trait loci for diapause and other photoperiodically regulated life history traits important in adaptation to seasonally varying environments. Molecular Ecology. 24: 2809-19. PMID 25877951 DOI: 10.1111/Mec.13202  1
2015 Ritchie MD, de Andrade M, Kuivaniemi H. The foundation of precision medicine: integration of electronic health records with genomics through basic, clinical, and translational research. Frontiers in Genetics. 6: 104. PMID 25852745 DOI: 10.3389/Fgene.2015.00104  1
2015 Lohse K, Clarke M, Ritchie MG, Etges WJ. Genome-wide tests for introgression between cactophilic Drosophila implicate a role of inversions during speciation. Evolution; International Journal of Organic Evolution. 69: 1178-90. PMID 25824653 DOI: 10.1111/Evo.12650  1
2015 Galvis LA, Holik AZ, Short KM, Pasquet J, Lun AT, Blewitt ME, Smyth IM, Ritchie ME, Asselin-Labat ML. Repression of Igf1 expression by Ezh2 prevents basal cell differentiation in the developing lung. Development (Cambridge, England). 142: 1458-69. PMID 25790853 DOI: 10.1242/dev.122077  1
2015 Wilkinson GS, Breden F, Mank JE, Ritchie MG, Higginson AD, Radwan J, Jaquiery J, Salzburger W, Arriero E, Barribeau SM, Phillips PC, Renn SC, Rowe L. The locus of sexual selection: moving sexual selection studies into the post-genomics era. Journal of Evolutionary Biology. 28: 739-55. PMID 25789690 DOI: 10.1111/Jeb.12621  1
2015 Pendergrass SA, Verma SS, Hall MA, Holzinger ER, Moore CB, Wallace JR, Dudek SM, Huggins W, Kitchner T, Waudby C, Berg R, Mccarty CA, Ritchie MD. Next-generation analysis of cataracts: determining knowledge driven gene-gene interactions using biofilter, and gene-environment interactions using the Phenx Toolkit*. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 495-505. PMID 25741542  1
2015 Terhzaz S, Teets NM, Cabrero P, Henderson L, Ritchie MG, Nachman RJ, Dow JA, Denlinger DL, Davies SA. Insect capa neuropeptides impact desiccation and cold tolerance. Proceedings of the National Academy of Sciences of the United States of America. 112: 2882-7. PMID 25730885 DOI: 10.1073/Pnas.1501518112  1
2015 Satzer D, DiBartolomeo C, Ritchie MM, Storino C, Liimatainen T, Hakkarainen H, Idiyatullin D, Mangia S, Michaeli S, Parr AM, Low WC. Assessment of dysmyelination with RAFFn MRI: application to murine MPS I. Plos One. 10: e0116788. PMID 25680196 DOI: 10.1371/journal.pone.0116788  1
2015 Veblen KE, Nehring KC, McGlone CM, Ritchie ME. Contrasting effects of different mammalian herbivores on sagebrush plant communities. Plos One. 10: e0118016. PMID 25671428 DOI: 10.1371/Journal.Pone.0118016  1
2015 Parker DJ, Vesala L, Ritchie MG, Laiho A, Hoikkala A, Kankare M. How consistent are the transcriptome changes associated with cold acclimation in two species of the Drosophila virilis group? Heredity. 115: 13-21. PMID 25669607 DOI: 10.1038/Hdy.2015.6  1
2015 Day GS, Ladak S, Curley K, Farb NA, Masiowski P, Pringsheim T, Ritchie M, Cheung A, Jansen S, Methot L, Neville HL, Bates D, Lowe D, Fernandes N, Ferland A, et al. Thiamine prescribing practices within university-affiliated hospitals: a multicenter retrospective review. Journal of Hospital Medicine. 10: 246-53. PMID 25652810 DOI: 10.1002/jhm.2324  1
2015 Ritchie ME, Phipson B, Wu D, Hu Y, Law CW, Shi W, Smyth GK. limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Research. 43: e47. PMID 25605792 DOI: 10.1093/nar/gkv007  1
2015 Kim D, Li R, Dudek SM, Wallace JR, Ritchie MD. Binning somatic mutations based on biological knowledge for predicting survival: an application in renal cell carcinoma. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 96-107. PMID 25592572  1
2015 Ritchie MD, Holzinger ER, Li R, Pendergrass SA, Kim D. Methods of integrating data to uncover genotype-phenotype interactions. Nature Reviews. Genetics. 16: 85-97. PMID 25582081 DOI: 10.1038/nrg3868  1
2015 Alexander JJ, Chaves LD, Chang A, Jacob A, Ritchie M, Quigg RJ. CD11b is protective in complement-mediated immune complex glomerulonephritis. Kidney International. 87: 930-9. PMID 25565310 DOI: 10.1038/ki.2014.373  1
2015 Smith G, Smith C, Kenny JG, Chaudhuri RR, Ritchie MG. Genome-wide DNA methylation patterns in wild samples of two morphotypes of threespine stickleback (Gasterosteus aculeatus). Molecular Biology and Evolution. 32: 888-95. PMID 25534027 DOI: 10.1093/Molbev/Msu344  1
2015 Ritchie MD. Finding the epistasis needles in the genome-wide haystack. Methods in Molecular Biology (Clifton, N.J.). 1253: 19-33. PMID 25403525 DOI: 10.1007/978-1-4939-2155-3_2  1
2015 Chen HS, Hutter CM, Mechanic LE, Amos CI, Bafna V, Hauser ER, Hernandez RD, Li C, Liberles DA, McAllister K, Moore JH, Paltoo DN, Papanicolaou GJ, Peng B, Ritchie MD, et al. Genetic simulation tools for post-genome wide association studies of complex diseases. Genetic Epidemiology. 39: 11-9. PMID 25371374 DOI: 10.1002/Gepi.21870  1
2015 Crosslin DR, Carrell DS, Burt A, Kim DS, Underwood JG, Hanna DS, Comstock BA, Baldwin E, de Andrade M, Kullo IJ, Tromp G, Kuivaniemi H, Borthwick KM, McCarty CA, Peissig PL, ... Ritchie MD, et al. Genetic variation in the HLA region is associated with susceptibility to herpes zoster. Genes and Immunity. 16: 1-7. PMID 25297839 DOI: 10.1038/Gene.2014.51  1
2015 Kim D, Joung JG, Sohn KA, Shin H, Park YR, Ritchie MD, Kim JH. Knowledge boosting: a graph-based integration approach with multi-omics data and genomic knowledge for cancer clinical outcome prediction. Journal of the American Medical Informatics Association : Jamia. 22: 109-20. PMID 25002459 DOI: 10.1136/Amiajnl-2013-002481  1
2015 Waduud MA, Choong WL, Ritchie M, Williams C, Yadavali R, Lim S, Buchanan F, Bhat R, Ramanathan K, Ingram S, Cormack L, Moss JG. Endovascular aneurysm repair: is imaging surveillance robust, and does it influence long-term mortality? Cardiovascular and Interventional Radiology. 38: 33-9. PMID 24722898 DOI: 10.1007/s00270-014-0890-5  1
2015 Hart OR, Uden RM, McMullan JE, Ritchie MS, Williams TD, Smith BH. A study of National Health Service management of chronic osteoarthritis and low back pain. Primary Health Care Research & Development. 16: 157-66. PMID 24674890 DOI: 10.1017/S1463423614000140  0.01
2015 Soka G, Ritchie M. Arbuscular mycorrhizal symbiosis, ecosystem processes and environmental changes in tropical soils Applied Ecology and Environmental Research. 13: 229-245. DOI: 10.15666/aeer/1301_229245  1
2015 Crosslin DR, Robertson PD, Carrell DS, Gordon AS, Hanna DS, Burt A, Fullerton SM, Scrol A, Ralston J, Leppig K, Hartzler A, Baldwin E, Andrade Md, Kullo IJ, Tromp G, ... ... Ritchie MD, et al. Prospective participant selection and ranking to maximize actionable pharmacogenetic variants and discovery in the eMERGE Network Genome Medicine. DOI: 10.1186/s13073-015-0181-z  1
2015 Pendergrass SA, Verma A, Okula A, Hall MA, Crawford DC, Ritchie MD, Génin E, Devoto M, Li H, Jeng J, Wu Q, Ziegler A, Mwambi H, König IR, Pineda S, et al. Contents Vol. 79, 2015 Human Heredity. 79. DOI: 10.1159/000382044  1
2015 Pendergrass SA, Verma A, Okula A, Hall MA, Crawford DC, Ritchie MD. Phenome-Wide Association Studies: Embracing Complexity for Discovery Human Heredity. 79: 111-123. DOI: 10.1159/000381851  1
2015 Crawford DC, Goodloe R, Farber-Eger E, Boston J, Pendergrass SA, Haines JL, Ritchie MD, Bush WS. Leveraging Epidemiologic and Clinical Collections for Genomic Studies of Complex Traits Human Heredity. 79: 137-146. DOI: 10.1159/000381805  1
2015 Ritchie M, Awal D, Eyeson JD. Availability of apicoectomy information online Oral Surgery. DOI: 10.1111/ors.12177  1
2015 Fioranelli F, Ritchie M, Griffiths H. Analysis of polarimetric multistatic human micro-Doppler classification of armed/unarmed personnel Ieee National Radar Conference - Proceedings. 2015: 432-437. DOI: 10.1109/RADAR.2015.7131038  1
2015 Rosenberg L, Watts S, Bocquet S, Ritchie M. Characterisation of the Ingara HGA dataset Ieee National Radar Conference - Proceedings. 2015: 27-32. DOI: 10.1109/RADAR.2015.7130965  1
2015 Fioranelli F, Ritchie M, Griffiths H. Classification of Unarmed/Armed Personnel Using the NetRAD Multistatic Radar for Micro-Doppler and Singular Value Decomposition Features Ieee Geoscience and Remote Sensing Letters. DOI: 10.1109/LGRS.2015.2439393  1
2015 Ash M, Ritchie M, Chetty K, Brennan PV. A New Multistatic FMCW Radar Architecture by Over-the-Air Deramping Ieee Sensors Journal. 15: 7045-7053. DOI: 10.1109/JSEN.2015.2466477  1
2015 Marquet PA, Allen AP, Brown JH, Dunne JA, Enquist BJ, Gillooly JF, Gowaty PA, Harte J, Hubbell SP, Okie JG, Ostling A, Ritchie M, Storch D, West GB. On the importance of first principles in ecological theory development Bioscience. 65: 342-343. DOI: 10.1093/Biosci/Biv015  1
2015 Ritchie M. Feeling for the State: Affective Labor and Anti-Terrorism Training in US Hotels Communication and Critical/ Cultural Studies. 12: 179-197. DOI: 10.1080/14791420.2015.1023816  1
2015 Fioranelli F, Ritchie M, Griffiths H. Aspect angle dependence and multistatic data fusion for micro-Doppler classification of armed/unarmed personnel Iet Radar, Sonar and Navigation. 9: 1231-1239. DOI: 10.1049/iet-rsn.2015.0058  1
2015 Fioranelli F, Ritchie M, Griffiths H. Multistatic human micro-Doppler classification of armed/unarmed personnel Iet Radar, Sonar and Navigation. 9: 857-865. DOI: 10.1049/iet-rsn.2014.0360  1
2015 Fioranelli F, Ritchie M, Griffiths H. Personnel recognition based on multistatic micro-Doppler and singular value decomposition features Electronics Letters. 51: 2143-2145. DOI: 10.1049/el.2015.3513  1
2015 Fioranelli F, Ritchie M, Griffiths H, Borrion H. Classification of loaded/unloaded microdrones using multistatic radar Electronics Letters. 51: 1813-1815. DOI: 10.1049/el.2015.3038  1
2015 Ritchie M, Fioranelli F, Balleri A, Griffiths HD. Measurement and analysis of multiband bistatic and monostatic radar signatures of wind turbines Electronics Letters. 51: 1112-1113. DOI: 10.1049/el.2015.0856  1
2015 Veltsos P, Gregson E, Morrissey B, Slate J, Hoikkala A, Butlin RK, Ritchie MG. The genetic architecture of sexually selected traits in two natural populations of Drosophila montana Heredity. DOI: 10.1038/hdy.2015.63  1
2015 Freitag D, Butterworth AS, Willeit P, Howson JMM, Burgess S, Kaptoge S, Young R, Ho WK, Wood AM, Sweeting M, Spackman S, Staley JR, Ramond A, Harshfield E, Nielsen SF, ... Ritchie MD, et al. Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: A Mendelian randomisation analysis The Lancet Diabetes and Endocrinology. 3: 243-253. DOI: 10.1016/S2213-8587(15)00034-0  1
2015 Antoninka AJ, Ritchie ME, Johnson NC. The hidden Serengeti-Mycorrhizal fungi respond to environmental gradients Pedobiologia. DOI: 10.1016/j.pedobi.2015.08.001  1
2015 Holik AZ, Galvis LA, Lun ATL, Ritchie ME, Asselin-Labat ML. Transcriptome and H3K27 tri-methylation profiling of Ezh2-deficient lung epithelium Genomics Data. 5: 346-351. DOI: 10.1016/j.gdata.2015.07.006  1
2015 Williams MS, Ritchie MD, Payne PRO. Interdisciplinary training to build an informatics workforce for precision medicine Applied and Translational Genomics. DOI: 10.1016/j.atg.2015.07.003  1
2015 Macnaught G, Ananthakrishnan G, Hinksman L, Yadavali R, Bryden F, Lassman S, Ritchie M, Gallacher K, Hay C, Moss JG. Can 1H MR Spectroscopy be Used to Assess the Success of Uterine Artery Embolisation? Cardiovascular and Interventional Radiology. DOI: 10.1007/s00270-015-1179-z  1
2015 Mahon M, Laux JM, Ritchie MH, Piazza NJ, Tiamiyu MF. Brief therapy at a university counseling center: Working alliance, readiness to change, and symptom severity Journal of College Counseling. 18: 233-243. DOI: 10.1002/Jocc.12017  1
2015 Vanmeter C, Laux JM, Piazza N, Ritchie M, Tucker-Gail K. Exploring the Value of the Substance Abuse Subtle Screening Inventory-3 for Predicting Attrition and Recidivism Among Perpetrators of Intimate Partner Violence Journal of Addictions and Offender Counseling. 36: 101-112. DOI: 10.1002/Jaoc.12006  1
2014 Jeff JM, Brown-Gentry K, Goodloe R, Ritchie MD, Denny JC, Kho AN, Armstrong LL, McClellan B, Mayo P, Allen M, Jin H, Gillani NB, Schnetz-Boutaud N, Dilks HH, Basford MA, et al. Replication of SCN5A Associations with Electrocardio-graphic Traits in African Americans from Clinical and Epidemiologic Studies. Evolutionary Computation, Machine Learning and Data Mining in Bioinformatics. Evobio (Conference), Author. 2014: 939-951. PMID 25590050 DOI: 10.1007/978-3-662-45523-4_76  1
2014 Verma SS, de Andrade M, Tromp G, Kuivaniemi H, Pugh E, Namjou-Khales B, Mukherjee S, Jarvik GP, Kottyan LC, Burt A, Bradford Y, Armstrong GD, Derr K, Crawford DC, Haines JL, ... Ritchie MD, et al. Imputation and quality control steps for combining multiple genome-wide datasets. Frontiers in Genetics. 5: 370. PMID 25566314 DOI: 10.3389/Fgene.2014.00370  1
2014 White MJ, McArthur K, Metcalf D, Lane RM, Cambier JC, Herold MJ, van Delft MF, Bedoui S, Lessene G, Ritchie ME, Huang DC, Kile BT. Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production. Cell. 159: 1549-62. PMID 25525874 DOI: 10.1016/J.Cell.2014.11.036  1
2014 Chhibber A, Kroetz DL, Tantisira KG, McGeachie M, Cheng C, Plenge R, Stahl E, Sadee W, Ritchie MD, Pendergrass SA. Genomic architecture of pharmacological efficacy and adverse events. Pharmacogenomics. 15: 2025-48. PMID 25521360 DOI: 10.2217/Pgs.14.144  1
2014 Namjou B, Marsolo K, Caroll RJ, Denny JC, Ritchie MD, Verma SS, Lingren T, Porollo A, Cobb BL, Perry C, Kottyan LC, Rothenberg ME, Thompson SD, Holm IA, Kohane IS, et al. Phenome-wide association study (PheWAS) in EMR-linked pediatric cohorts, genetically links PLCL1 to speech language development and IL5-IL13 to Eosinophilic Esophagitis. Frontiers in Genetics. 5: 401. PMID 25477900 DOI: 10.3389/Fgene.2014.00401  1
2014 Hall MA, Verma A, Brown-Gentry KD, Goodloe R, Boston J, Wilson S, McClellan B, Sutcliffe C, Dilks HH, Gillani NB, Jin H, Mayo P, Allen M, Schnetz-Boutaud N, Crawford DC, Ritchie MD, et al. Detection of pleiotropy through a Phenome-wide association study (PheWAS) of epidemiologic data as part of the Environmental Architecture for Genes Linked to Environment (EAGLE) study. Plos Genetics. 10: e1004678. PMID 25474351 DOI: 10.1371/Journal.Pgen.1004678  1
2014 Mack F, Ritchie M, Sapra P. The next generation of antibody drug conjugates. Seminars in Oncology. 41: 637-52. PMID 25440608 DOI: 10.1053/j.seminoncol.2014.08.001  1
2014 Malinowski JR, Denny JC, Bielinski SJ, Basford MA, Bradford Y, Peissig PL, Carrell D, Crosslin DR, Pathak J, Rasmussen L, Pacheco J, Kho A, Newton KM, Li R, Kullo IJ, ... Ritchie MD, et al. Genetic variants associated with serum thyroid stimulating hormone (TSH) levels in European Americans and African Americans from the eMERGE Network. Plos One. 9: e111301. PMID 25436638 DOI: 10.1371/Journal.Pone.0111301  1
2014 Crosslin DR, Tromp G, Burt A, Kim DS, Verma SS, Lucas AM, Bradford Y, Crawford DC, Armasu SM, Heit JA, Hayes MG, Kuivaniemi H, Ritchie MD, Jarvik GP, de Andrade M, et al. Controlling for population structure and genotyping platform bias in the eMERGE multi-institutional biobank linked to electronic health records. Frontiers in Genetics. 5: 352. PMID 25414722 DOI: 10.3389/Fgene.2014.00352  1
2014 Immonen E, Snook RR, Ritchie MG. Mating system variation drives rapid evolution of the female transcriptome in Drosophila pseudoobscura. Ecology and Evolution. 4: 2186-201. PMID 25360260 DOI: 10.1002/Ece3.1098  1
2014 Kirchner JE, Ritchie MJ, Pitcock JA, Parker LE, Curran GM, Fortney JC. Outcomes of a partnered facilitation strategy to implement primary care-mental health. Journal of General Internal Medicine. 29: 904-12. PMID 25355087 DOI: 10.1007/S11606-014-3027-2  1
2014 Ritchie MD, Verma SS, Hall MA, Goodloe RJ, Berg RL, Carrell DS, Carlson CS, Chen L, Crosslin DR, Denny JC, Jarvik G, Li R, Linneman JG, Pathak J, Peissig P, et al. Electronic medical records and genomics (eMERGE) network exploration in cataract: several new potential susceptibility loci. Molecular Vision. 20: 1281-95. PMID 25352737  1
2014 Siefert A, Fridley JD, Ritchie ME. Community functional responses to soil and climate at multiple spatial scales: when does intraspecific variation matter? Plos One. 9: e111189. PMID 25329794 DOI: 10.1371/Journal.Pone.0111189  1
2014 Barrie ES, Weinshenker D, Verma A, Pendergrass SA, Lange LA, Ritchie MD, Wilson JG, Kuivaniemi H, Tromp G, Carey DJ, Gerhard GS, Brilliant MH, Hebbring SJ, Cubells JF, Pinsonneault JK, et al. Regulatory polymorphisms in human DBH affect peripheral gene expression and sympathetic activity. Circulation Research. 115: 1017-25. PMID 25326128 DOI: 10.1161/Circresaha.116.304398  1
2014 Kim D, Li R, Dudek SM, Frase AT, Pendergrass SA, Ritchie MD. Knowledge-driven genomic interactions: an application in ovarian cancer. Biodata Mining. 7: 20. PMID 25214892 DOI: 10.1186/1756-0381-7-20  1
2014 Restrepo NA, Spencer KL, Goodloe R, Garrett TA, Heiss G, Bůžková P, Jorgensen N, Jensen RA, Matise TC, Hindorff LA, Klein BE, Klein R, Wong TY, Cheng CY, Cornes BK, ... Ritchie MD, et al. Genetic determinants of age-related macular degeneration in diverse populations from the PAGE study. Investigative Ophthalmology & Visual Science. 55: 6839-50. PMID 25205864 DOI: 10.1167/Iovs.14-14246  1
2014 Cronin RM, Field JR, Bradford Y, Shaffer CM, Carroll RJ, Mosley JD, Bastarache L, Edwards TL, Hebbring SJ, Lin S, Hindorff LA, Crane PK, Pendergrass SA, Ritchie MD, Crawford DC, et al. Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index. Frontiers in Genetics. 5: 250. PMID 25177340 DOI: 10.3389/Fgene.2014.00250  1
2014 Ciesielski TH, Pendergrass SA, White MJ, Kodaman N, Sobota RS, Huang M, Bartlett J, Li J, Pan Q, Gui J, Selleck SB, Amos CI, Ritchie MD, Moore JH, Williams SM. Diverse convergent evidence in the genetic analysis of complex disease: coordinating omic, informatic, and experimental evidence to better identify and validate risk factors. Biodata Mining. 7: 10. PMID 25071867 DOI: 10.1186/1756-0381-7-10  1
2014 Crawford DC, Crosslin DR, Tromp G, Kullo IJ, Kuivaniemi H, Hayes MG, Denny JC, Bush WS, Haines JL, Roden DM, McCarty CA, Jarvik GP, Ritchie MD. eMERGEing progress in genomics-the first seven years. Frontiers in Genetics. 5: 184. PMID 24987407 DOI: 10.3389/Fgene.2014.00184  1
2014 Kraja AT, Chasman DI, North KE, Reiner AP, Yanek LR, Kilpeläinen TO, Smith JA, Dehghan A, Dupuis J, Johnson AD, Feitosa MF, Tekola-Ayele F, Chu AY, Nolte IM, Dastani Z, ... Ritchie MD, et al. Pleiotropic genes for metabolic syndrome and inflammation. Molecular Genetics and Metabolism. 112: 317-38. PMID 24981077 DOI: 10.1016/J.Ymgme.2014.04.007  1
2014 Rasmussen-Torvik LJ, Stallings SC, Gordon AS, Almoguera B, Basford MA, Bielinski SJ, Brautbar A, Brilliant MH, Carrell DS, Connolly JJ, Crosslin DR, Doheny KF, Gallego CJ, Gottesman O, Kim DS, ... Ritchie MD, et al. Design and anticipated outcomes of the eMERGE-PGx project: a multicenter pilot for preemptive pharmacogenomics in electronic health record systems. Clinical Pharmacology and Therapeutics. 96: 482-9. PMID 24960519 DOI: 10.1038/Clpt.2014.137  1
2014 Debelle A, Ritchie MG, Snook RR. Evolution of divergent female mating preference in response to experimental sexual selection. Evolution; International Journal of Organic Evolution. 68: 2524-33. PMID 24931497 DOI: 10.1111/Evo.12473  1
2014 Liu R, Dai Z, Yeager M, Irizarry RA, Ritchie ME. KRLMM: an adaptive genotype calling method for common and low frequency variants. Bmc Bioinformatics. 15: 158. PMID 24886250 DOI: 10.1186/1471-2105-15-158  1
2014 Pascoal S, Cezard T, Eik-Nes A, Gharbi K, Majewska J, Payne E, Ritchie MG, Zuk M, Bailey NW. Rapid convergent evolution in wild crickets. Current Biology : Cb. 24: 1369-74. PMID 24881880 DOI: 10.1016/J.Cub.2014.04.053  1
2014 Dai Z, Sheridan JM, Gearing LJ, Moore DL, Su S, Wormald S, Wilcox S, O'Connor L, Dickins RA, Blewitt ME, Ritchie ME. edgeR: a versatile tool for the analysis of shRNA-seq and CRISPR-Cas9 genetic screens. F1000research. 3: 95. PMID 24860646 DOI: 10.12688/f1000research.3928.2  1
2014 Glennon KL, Ritchie ME, Segraves KA. Evidence for shared broad-scale climatic niches of diploid and polyploid plants. Ecology Letters. 17: 574-82. PMID 24818236 DOI: 10.1111/Ele.12259  1
2014 Sun X, Lu Q, Mukherjee S, Mukheerjee S, Crane PK, Elston R, Ritchie MD. Analysis pipeline for the epistasis search - statistical versus biological filtering. Frontiers in Genetics. 5: 106. PMID 24817878 DOI: 10.3389/Fgene.2014.00106  1
2014 Merola JS, Slebodnick C, Berg M, Ritchie MK. mer-Hydridotris(tri-methyl-phosphane-κP)(d-valinato-κ(2) N,O)iridium hexa-fluorido-phosphate di-chloro-methane 0.675-solvate. Acta Crystallographica. Section E, Structure Reports Online. 70: m82. PMID 24764947 DOI: 10.1107/S1600536814002165  1
2014 Wentworth JM, Playfair J, Laurie C, Ritchie ME, Brown WA, Burton P, Shaw JE, O'Brien PE. Multidisciplinary diabetes care with and without bariatric surgery in overweight people: a randomised controlled trial. The Lancet. Diabetes & Endocrinology. 2: 545-52. PMID 24731535 DOI: 10.1016/S2213-8587(14)70066-X  1
2014 Eby SL, Anderson TM, Mayemba EP, Ritchie ME. The effect of fire on habitat selection of mammalian herbivores: the role of body size and vegetation characteristics. The Journal of Animal Ecology. 83: 1196-205. PMID 24697568 DOI: 10.1111/1365-2656.12221  1
2014 Engelhardt KA, Ritchie ME, Powell JA. Body size mediated coexistence in swans. Thescientificworldjournal. 2014: 643694. PMID 24672347 DOI: 10.1155/2014/643694  1
2014 Jeff JM, Armstrong LL, Ritchie MD, Denny JC, Kho AN, Basford MA, Wolf WA, Pacheco JA, Li R, Chisholm RL, Roden DM, Hayes MG, Crawford DC. Admixture mapping and subsequent fine-mapping suggests a biologically relevant and novel association on chromosome 11 for type 2 diabetes in African Americans. Plos One. 9: e86931. PMID 24595071 DOI: 10.1371/Journal.Pone.0086931  1
2014 Kirchner JE, Kearney LK, Ritchie MJ, Dollar KM, Swensen AB, Schohn M. Research & services partnerships: lessons learned through a national partnership between clinical leaders and researchers. Psychiatric Services (Washington, D.C.). 65: 577-9. PMID 24585229 DOI: 10.1176/Appi.Ps.201400054  1
2014 Kim D, Shin H, Sohn KA, Verma A, Ritchie MD, Kim JH. Incorporating inter-relationships between different levels of genomic data into cancer clinical outcome prediction. Methods (San Diego, Calif.). 67: 344-53. PMID 24561168 DOI: 10.1016/J.Ymeth.2014.02.003  1
2014 Johnson DH, Venuto C, Ritchie MD, Morse GD, Daar ES, McLaren PJ, Haas DW. Genomewide association study of atazanavir pharmacokinetics and hyperbilirubinemia in AIDS Clinical Trials Group protocol A5202. Pharmacogenetics and Genomics. 24: 195-203. PMID 24557078 DOI: 10.1097/Fpc.0000000000000034  1
2014 Chhibber A, Mefford J, Stahl EA, Pendergrass SA, Baldwin RM, Owzar K, Li M, Winer EP, Hudis CA, Zembutsu H, Kubo M, Nakamura Y, McLeod HL, Ratain MJ, Shulman LN, Ritchie MD, et al. Polygenic inheritance of paclitaxel-induced sensory peripheral neuropathy driven by axon outgrowth gene sets in CALGB 40101 (Alliance). The Pharmacogenomics Journal. 14: 336-42. PMID 24513692 DOI: 10.1038/Tpj.2014.2  1
2014 Ritchie ME. Plant compensation to grazing and soil carbon dynamics in a tropical grassland. Peerj. 2: e233. PMID 24498573 DOI: 10.7717/peerj.233  1
2014 Ritchie MJ, Dollar KM, Kearney LK, Kirchner JE. Research and services partnerships: Responding to needs of clinical operations partners: transferring implementation facilitation knowledge and skills. Psychiatric Services (Washington, D.C.). 65: 141-3. PMID 24492898 DOI: 10.1176/Appi.Ps.201300468  1
2014 Ritchie M, Berthouze L, House T, Kiss IZ. Higher-order structure and epidemic dynamics in clustered networks. Journal of Theoretical Biology. 348: 21-32. PMID 24486653 DOI: 10.1016/j.jtbi.2014.01.025  1
2014 Neville MC, Nojima T, Ashley E, Parker DJ, Walker J, Southall T, Van de Sande B, Marques AC, Fischer B, Brand AH, Russell S, Ritchie MG, Aerts S, Goodwin SF. Male-specific fruitless isoforms target neurodevelopmental genes to specify a sexually dimorphic nervous system. Current Biology : Cb. 24: 229-41. PMID 24440396 DOI: 10.1016/J.Cub.2013.11.035  1
2014 McCarty CA, Berg R, Rottscheit CM, Waudby CJ, Kitchner T, Brilliant M, Ritchie MD. Validation of PhenX measures in the personalized medicine research project for use in gene/environment studies. Bmc Medical Genomics. 7: 3. PMID 24423110 DOI: 10.1186/1755-8794-7-3  1
2014 Wentworth JM, Hensman T, Playfair J, Laurie C, Ritchie ME, Brown WA, Skinner S, Shaw JE, O'Brien PE. Laparoscopic adjustable gastric banding and progression from impaired fasting glucose to diabetes. Diabetologia. 57: 463-8. PMID 24310563 DOI: 10.1007/s00125-013-3129-0  1
2014 Hall MA, Dudek SM, Goodloe R, Crawford DC, Pendergrass SA, Peissig P, Brilliant M, McCarty CA, Ritchie MD. Environment-wide association study (EWAS) for type 2 diabetes in the Marshfield Personalized Medicine Research Project Biobank. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 200-11. PMID 24297547  1
2014 Ritchie M. Neuroanatomy and physiology of the avian hypothalamic/pituitary axis: clinical aspects. The Veterinary Clinics of North America. Exotic Animal Practice. 17: 13-22. PMID 24274919 DOI: 10.1016/j.cvex.2013.09.005  1
2014 Parker DJ, Gardiner A, Neville MC, Ritchie MG, Goodwin SF. The evolution of novelty in conserved genes; evidence of positive selection in the Drosophila fruitless gene is localised to alternatively spliced exons. Heredity. 112: 300-6. PMID 24149653 DOI: 10.1038/Hdy.2013.106  1
2014 Holzinger ER, Dudek SM, Frase AT, Pendergrass SA, Ritchie MD. ATHENA: the analysis tool for heritable and environmental network associations. Bioinformatics (Oxford, England). 30: 698-705. PMID 24149050 DOI: 10.1093/Bioinformatics/Btt572  1
2014 Shameer K, Denny JC, Ding K, Jouni H, Crosslin DR, de Andrade M, Chute CG, Peissig P, Pacheco JA, Li R, Bastarache L, Kho AN, Ritchie MD, Masys DR, Chisholm RL, et al. A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects. Human Genetics. 133: 95-109. PMID 24026423 DOI: 10.1007/S00439-013-1355-7  1
2014 Ritchie MW, Knapp EE. Establishment of a long-term fire salvage study in an interior ponderosa pine forest Journal of Forestry. 112: 395-400. DOI: 10.5849/jof.13-093  1
2014 Crotteau JS, Ritchie MW. Long-term stand growth of interior ponderosa pine stands in response to structural modifications and burning treatments in Northeastern California Journal of Forestry. 112: 412-423. DOI: 10.5849/jof.13-090  1
2014 Crotteau JS, Ritchie MW, Varner JM. A mixed-effects heterogeneous negative binomial model for Postfire conifer regeneration in northeastern California, USA Forest Science. 60: 275-287. DOI: 10.5849/forsci.12-089  1
2014 Kim D, Ritchie MD. Data Integration for Cancer Clinical Outcome Prediction Journal of Health and Medical Informatics. 5: 1-2. DOI: 10.4172/2157-7420.1000E122  1
2014 Ritchie ME, Dai Z, Sheridan JM, Gearing LJ, Moore DL, Su S, Dickins RA, Blewitt ME. ShRNA-seq data analysis with edgeR F1000research. 3. DOI: 10.12688/f1000research.3928.1  1
2014 Brown S, Ritchie M. Discussion on "Necessary changes to CSA A23.3-04 (R2010) relevant to punching shear design for unbalanced moment transfer" Canadian Journal of Civil Engineering. 41: 775. DOI: 10.1139/cjce-2014-0138  1
2014 Inggs M, Griffiths H, Fioranelli F, Ritchie M, Woodbridge K. Multistatic radar: System requirements and experimental validation 2014 International Radar Conference, Radar 2014. DOI: 10.1109/RADAR.2014.7060435  1
2014 Watts S, Rosenberg L, Ritchie M. Characterising the Doppler spectra of high grazing angle sea clutter 2014 International Radar Conference, Radar 2014. DOI: 10.1109/RADAR.2014.7060346  1
2014 Ritchie MA, Griffiths HD, Watts S, Rosenberg L. Statistical comparison of low and high grazing angle sea clutter 2014 International Radar Conference, Radar 2014. DOI: 10.1109/RADAR.2014.7060274  1
2014 De R, Holmes MV, Moore JH, Ritchie MD, Verma SS, Asselbergs FW, Keating BJ, Gilbert-Diamond D. Dissecting the obesity disease landscape: Identifying gene-gene interactions that are highly associated with body mass index International Conference On Systems Biology, Isb. 124-131. DOI: 10.1109/ISB.2014.6990744  1
2014 Marquet PA, Allen AP, Brown JH, Dunne JA, Enquist BJ, Gillooly JF, Gowaty PA, Green JL, Harte J, Hubbell SP, O'Dwyer J, Okie JG, Ostling A, Ritchie M, Storch D, et al. On theory in ecology Bioscience. 64: 701-710. DOI: 10.1093/Biosci/Biu098  1
2014 Jenkins CD, Laux JM, Ritchie MH, Tucker-Gail K. Animal-Assisted Therapy and Rogers' Core Components Among Middle School Students Receiving Counseling Services: A Descriptive Study Journal of Creativity in Mental Health. 9: 174-187. DOI: 10.1080/15401383.2014.899939  1
2014 Lockard FW, Laux JM, Ritchie M, Piazza N, Haefner J. Perceived Leadership Preparation in Counselor Education Doctoral Students Who Are Members of the American Counseling Association in CACREP-Accredited Programs Clinical Supervisor. 33: 228-242. DOI: 10.1080/07325223.2014.992270  1
2014 Testa PF, Hibbing MV, Ritchie M. Orientations toward conflict and the conditional effects of political disagreement Journal of Politics. 76: 770-785. DOI: 10.1017/S0022381614000255  1
2014 Wing BM, Ritchie MW, Boston K, Cohen WB, Olsen MJ. Individual snag detection using neighborhood attribute filtered airborne lidar data Remote Sensing of Environment. DOI: 10.1016/J.Rse.2015.03.013  1
2014 Ritchie M, Nelson K, Wills R, Jones L. Development of an Audit Tool to Evaluate the Documentation of Partner Abuse Assessments within a Provincial Emergency Department: An Exploratory Study Journal of Family Violence. 29: 215-221. DOI: 10.1007/s10896-013-9566-1  1
2014 Schmitz OJ, Raymond PA, Estes JA, Kurz WA, Holtgrieve GW, Ritchie ME, Schindler DE, Spivak AC, Wilson RW, Bradford MA, Christensen V, Deegan L, Smetacek V, Vanni MJ, Wilmers CC. Animating the carbon cycle Ecosystems. 17: 344-359. DOI: 10.1007/S10021-013-9715-7  1
2014 Ala-Honkola O, Veltsos P, Anderson H, Ritchie MG. Copulation duration, but not paternity share, potentially mediates inbreeding avoidance in Drosophila montana Behavioral Ecology and Sociobiology. 68: 2013-2021. DOI: 10.1007/S00265-014-1807-7  1
2014 Li R, Kim D, Dudek SM, Ritchie MD. An integrated analysis of genome-wide DNA Methylation and genetic variants underlying etoposide-induced cytotoxicity in European and African populations Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 8602: 928-938. DOI: 10.1007/978-3-662-45523-4_75  1
2014 Verma SS, Peissig P, Cross D, Waudby C, Brilliant M, McCarty CA, Ritchie MD. Benefits of accurate imputations in GWAS Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 8602: 877-889. DOI: 10.1007/978-3-662-45523-4_71  1
2014 Ritchie MW, Skinner CN. Interdisciplinary research on the blacks mountain experimental forest Usda Forest Service Experimental Forests and Ranges: Research For the Long Term. 2147483647: 129-146. DOI: 10.1007/978-1-4614-1818-4_6  1
2014 Delaney RB, Laux JM, Piazza NJ, Ritchie MH, Jenkins M. Predicting desistance or persistence in the substance-abusing, mentally ill, supervised offender population using Laub and Sampson's (2001) social controls and individual factors theory Journal of Addictions and Offender Counseling. 35: 2-14. DOI: 10.1002/J.2161-1874.2014.00020.X  1
2014 Altman RB, Dunker AK, Hunter L, Klein TE, Ritchie MD. Pacific symposium on biocomputing 2014 19th Pacific Symposium On Biocomputing, Psb 2014. v-vi.  1
2013 Kim D, Kim S, Risacher SL, Shen L, Ritchie MD, Weiner MW, Saykin AJ, Nho K. A Graph-Based Integration of Multimodal Brain Imaging Data for the Detection of Early Mild Cognitive Impairment (E-MCI). Multimodal Brain Image Analysis : Third International Workshop, Mbia 2013, Held in Conjunction With Miccai 2013, Nagoya, Japan, September 22, 2013 : Proceedings / Li Shen, Tianming Liu, Pew-Thian Yap, Heng Huang, Dinggang Shen, Carl-Fre.... 8159: 159-169. PMID 25383392 DOI: 10.1007/978-3-319-02126-3_16  1
2013 Vigoder Fde M, Ritchie MG, Gibson G, Peixoto AA. Acoustic communication in insect disease vectors. MemóRias Do Instituto Oswaldo Cruz. 108: 26-33. PMID 24473800 DOI: 10.1590/0074-0276130390  1
2013 Moore CB, Wallace JR, Wolfe DJ, Frase AT, Pendergrass SA, Weiss KM, Ritchie MD. Low frequency variants, collapsed based on biological knowledge, uncover complexity of population stratification in 1000 genomes project data. Plos Genetics. 9: e1003959. PMID 24385916 DOI: 10.1371/Journal.Pgen.1003959  1
2013 Pendergrass SA, Frase A, Wallace J, Wolfe D, Katiyar N, Moore C, Ritchie MD. Genomic analyses with biofilter 2.0: knowledge driven filtering, annotation, and model development. Biodata Mining. 6: 25. PMID 24378202 DOI: 10.1186/1756-0381-6-25  1
2013 Kim D, Li R, Dudek SM, Ritchie MD. ATHENA: Identifying interactions between different levels of genomic data associated with cancer clinical outcomes using grammatical evolution neural network. Biodata Mining. 6: 23. PMID 24359638 DOI: 10.1186/1756-0381-6-23  1
2013 Mosley JD, Van Driest SL, Larkin EK, Weeke PE, Witte JS, Wells QS, Karnes JH, Guo Y, Bastarache L, Olson LM, McCarty CA, Pacheco JA, Jarvik GP, Carrell DS, Larson EB, ... Ritchie MD, et al. Mechanistic phenotypes: an aggregative phenotyping strategy to identify disease mechanisms using GWAS data. Plos One. 8: e81503. PMID 24349080 DOI: 10.1371/Journal.Pone.0081503  1
2013 Chen CC, Watada M, Miyake H, Katoh TK, Sun Z, Li YF, Ritchie MG, Wen SY. Courtship patterns in the Drosophila montium species subgroup: repeated loss of precopulatory courtship? Zoological Science. 30: 1056-62. PMID 24320184 DOI: 10.2108/Zsj.30.1056  1
2013 Denny JC, Bastarache L, Ritchie MD, Carroll RJ, Zink R, Mosley JD, Field JR, Pulley JM, Ramirez AH, Bowton E, Basford MA, Carrell DS, Peissig PL, Kho AN, Pacheco JA, et al. Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data. Nature Biotechnology. 31: 1102-10. PMID 24270849 DOI: 10.1038/Nbt.2749  1
2013 Hall NJ, Rubin GP, Dobson C, Weller D, Wardle J, Ritchie M, Rees CJ. Attitudes and beliefs of non-participants in a population-based screening programme for colorectal cancer. Health Expectations : An International Journal of Public Participation in Health Care and Health Policy. PMID 24268129 DOI: 10.1111/hex.12157  1
2013 Behr ER, Ritchie MD, Tanaka T, Kääb S, Crawford DC, Nicoletti P, Floratos A, Sinner MF, Kannankeril PJ, Wilde AA, Bezzina CR, Schulze-Bahr E, Zumhagen S, Guicheney P, Bishopric NH, et al. Genome wide analysis of drug-induced torsades de pointes: lack of common variants with large effect sizes. Plos One. 8: e78511. PMID 24223155 DOI: 10.1371/Journal.Pone.0078511  1
2013 Wolfe D, Dudek S, Ritchie MD, Pendergrass SA. Visualizing genomic information across chromosomes with PhenoGram. Biodata Mining. 6: 18. PMID 24131735 DOI: 10.1186/1756-0381-6-18  1
2013 Gong J, Schumacher F, Lim U, Hindorff LA, Haessler J, Buyske S, Carlson CS, Rosse S, Bůžková P, Fornage M, Gross M, Pankratz N, Pankow JS, Schreiner PJ, Cooper R, ... Ritchie MD, et al. Fine Mapping and Identification of BMI Loci in African Americans. American Journal of Human Genetics. 93: 661-71. PMID 24094743 DOI: 10.1016/J.Ajhg.2013.08.012  1
2013 Carlson CS, Matise TC, North KE, Haiman CA, Fesinmeyer MD, Buyske S, Schumacher FR, Peters U, Franceschini N, Ritchie MD, Duggan DJ, Spencer KL, Dumitrescu L, Eaton CB, Thomas F, et al. Generalization and dilution of association results from European GWAS in populations of non-European ancestry: the PAGE study. Plos Biology. 11: e1001661. PMID 24068893 DOI: 10.1371/Journal.Pbio.1001661  1
2013 Hulgan T, Stein JH, Cotter BR, Murdock DG, Ritchie MD, Dube MP, Gerschenson M, Haas DW, Torriani FJ. Mitochondrial DNA variation and changes in adiponectin and endothelial function in HIV-infected adults after antiretroviral therapy initiation. Aids Research and Human Retroviruses. 29: 1293-9. PMID 23944767 DOI: 10.1089/Aid.2013.0079  1
2013 Pare G, Kubo M, Byrd JB, McCarty CA, Woodard-Grice A, Teo KK, Anand SS, Zuvich RL, Bradford Y, Ross S, Nakamura Y, Ritchie M, Brown NJ. Genetic variants associated with angiotensin-converting enzyme inhibitor-associated angioedema. Pharmacogenetics and Genomics. 23: 470-8. PMID 23838604 DOI: 10.1097/Fpc.0B013E328363C137  1
2013 Park SL, Cheng I, Pendergrass SA, Kucharska-Newton AM, Lim U, Ambite JL, Caberto CP, Monroe KR, Schumacher F, Hindorff LA, Oetjens MT, Wilson S, Goodloe RJ, Love SA, Henderson BE, ... Ritchie MD, et al. Association of the FTO obesity risk variant rs8050136 with percentage of energy intake from fat in multiple racial/ethnic populations: the PAGE study. American Journal of Epidemiology. 178: 780-90. PMID 23820787 DOI: 10.1093/Aje/Kwt028  1
2013 Moore CB, Wallace JR, Frase AT, Pendergrass SA, Ritchie MD. BioBin: a bioinformatics tool for automating the binning of rare variants using publicly available biological knowledge. Bmc Medical Genomics. 6: S6. PMID 23819467 DOI: 10.1186/1755-8794-6-S2-S6  1
2013 McDavid A, Crane PK, Newton KM, Crosslin DR, McCormick W, Weston N, Ehrlich K, Hart E, Harrison R, Kukull WA, Rottscheit C, Peissig P, Stefanski E, McCarty CA, Zuvich RL, Ritchie MD, et al. Enhancing the power of genetic association studies through the use of silver standard cases derived from electronic medical records. Plos One. 8: e63481. PMID 23762230 DOI: 10.1371/Journal.Pone.0063481  1
2013 Gottesman O, Kuivaniemi H, Tromp G, Faucett WA, Li R, Manolio TA, Sanderson SC, Kannry J, Zinberg R, Basford MA, Brilliant M, Carey DJ, Chisholm RL, Chute CG, Connolly JJ, ... Ritchie MD, et al. The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 15: 761-71. PMID 23743551 DOI: 10.1038/Gim.2013.72  1
2013 Fesinmeyer MD, North KE, Ritchie MD, Lim U, Franceschini N, Wilkens LR, Gross MD, Bůžková P, Glenn K, Quibrera PM, Fernández-Rhodes L, Li Q, Fowke JH, Li R, Carlson CS, et al. Genetic risk factors for BMI and obesity in an ethnically diverse population: results from the population architecture using genomics and epidemiology (PAGE) study. Obesity (Silver Spring, Md.). 21: 835-46. PMID 23712987 DOI: 10.1002/Oby.20268  1
2013 Ding K, de Andrade M, Manolio TA, Crawford DC, Rasmussen-Torvik LJ, Ritchie MD, Denny JC, Masys DR, Jouni H, Pachecho JA, Kho AN, Roden DM, Chisholm R, Kullo IJ. Genetic variants that confer resistance to malaria are associated with red blood cell traits in African-Americans: an electronic medical record-based genome-wide association study. G3 (Bethesda, Md.). 3: 1061-8. PMID 23696099 DOI: 10.1534/G3.113.006452  1
2013 Oetjens MT, Denny JC, Ritchie MD, Gillani NB, Richardson DM, Restrepo NA, Pulley JM, Dilks HH, Basford MA, Bowton E, Masys DR, Wilke RA, Roden DM, Crawford DC. Assessment of a pharmacogenomic marker panel in a polypharmacy population identified from electronic medical records. Pharmacogenomics. 14: 735-44. PMID 23651022 DOI: 10.2217/Pgs.13.64  1
2013 Zhang L, Buzkova P, Wassel CL, Roman MJ, North KE, Crawford DC, Boston J, Brown-Gentry KD, Cole SA, Deelman E, Goodloe R, Wilson S, Heiss G, Jenny NS, Jorgensen NW, ... Ritchie MD, et al. Lack of associations of ten candidate coronary heart disease risk genetic variants and subclinical atherosclerosis in four US populations: the Population Architecture using Genomics and Epidemiology (PAGE) study. Atherosclerosis. 228: 390-9. PMID 23587283 DOI: 10.1016/J.Atherosclerosis.2013.02.038  1
2013 Girirajan S, Johnson RL, Tassone F, Balciuniene J, Katiyar N, Fox K, Baker C, Srikanth A, Yeoh KH, Khoo SJ, Nauth TB, Hansen R, Ritchie M, Hertz-Picciotto I, Eichler EE, et al. Global increases in both common and rare copy number load associated with autism. Human Molecular Genetics. 22: 2870-80. PMID 23535821 DOI: 10.1093/Hmg/Ddt136  1
2013 Jeff JM, Ritchie MD, Denny JC, Kho AN, Ramirez AH, Crosslin D, Armstrong L, Basford MA, Wolf WA, Pacheco JA, Chisholm RL, Roden DM, Hayes MG, Crawford DC. Generalization of variants identified by genome-wide association studies for electrocardiographic traits in African Americans. Annals of Human Genetics. 77: 321-32. PMID 23534349 DOI: 10.1111/Ahg.12023  1
2013 McGeachie MJ, Stahl EA, Himes BE, Pendergrass SA, Lima JJ, Irvin CG, Peters SP, Ritchie MD, Plenge RM, Tantisira KG. Polygenic heritability estimates in pharmacogenetics: focus on asthma and related phenotypes. Pharmacogenetics and Genomics. 23: 324-8. PMID 23532052 DOI: 10.1097/Fpc.0B013E3283607Acf  1
2013 Ritchie MD, Denny JC, Zuvich RL, Crawford DC, Schildcrout JS, Bastarache L, Ramirez AH, Mosley JD, Pulley JM, Basford MA, Bradford Y, Rasmussen LV, Pathak J, Chute CG, Kullo IJ, et al. Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk. Circulation. 127: 1377-85. PMID 23463857 DOI: 10.1161/Circulationaha.112.000604  1
2013 Spencer KL, Malinowski J, Carty CL, Franceschini N, Fernández-Rhodes L, Young A, Cheng I, Ritchie MD, Haiman CA, Wilkens L, Chunyuanwu, Matise TC, Carlson CS, Brennan K, Park A, et al. Genetic variation and reproductive timing: African American women from the Population Architecture using Genomics and Epidemiology (PAGE) Study. Plos One. 8: e55258. PMID 23424626 DOI: 10.1371/Journal.Pone.0055258  1
2013 Bush WS, Boston J, Pendergrass SA, Dumitrescu L, Goodloe R, Brown-Gentry K, Wilson S, McClellan B, Torstenson E, Basford MA, Spencer KL, Ritchie MD, Crawford DC. Enabling high-throughput genotype-phenotype associations in the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) project as part of the Population Architecture using Genomics and Epidemiology (PAGE) study. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 373-84. PMID 23424142  1
2013 Moore CB, Wallace JR, Frase AT, Pendergrass SA, Ritchie MD. Using BioBin to explore rare variant population stratification. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 332-43. PMID 23424138  1
2013 Crawford DC, Goodloe R, Brown-Gentry K, Wilson S, Roberson J, Gillani NB, Ritchie MD, Dilks HH, Bush WS. Characterization of the Metabochip in diverse populations from the International HapMap Project in the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) project. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 188-99. PMID 23424124  1
2013 Pendergrass SA, Verma SS, Holzinger ER, Moore CB, Wallace J, Dudek SM, Huggins W, Kitchner T, Waudby C, Berg R, McCarty CA, Ritchie MD. Next-generation analysis of cataracts: determining knowledge driven gene-gene interactions using Biofilter, and gene-environment interactions using the PhenX Toolkit. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 147-58. PMID 23424120  1
2013 Pendergrass SA, Brown-Gentry K, Dudek S, Frase A, Torstenson ES, Goodloe R, Ambite JL, Avery CL, Buyske S, Bůžková P, Deelman E, Fesinmeyer MD, Haiman CA, Heiss G, Hindorff LA, ... Ritchie MD, et al. Phenome-wide association study (PheWAS) for detection of pleiotropy within the Population Architecture using Genomics and Epidemiology (PAGE) Network. Plos Genetics. 9: e1003087. PMID 23382687 DOI: 10.1371/Journal.Pgen.1003087  1
2013 Peters U, North KE, Sethupathy P, Buyske S, Haessler J, Jiao S, Fesinmeyer MD, Jackson RD, Kuller LH, Rajkovic A, Lim U, Cheng I, Schumacher F, Wilkens L, Li R, ... Ritchie M, et al. A systematic mapping approach of 16q12.2/FTO and BMI in more than 20,000 African Americans narrows in on the underlying functional variation: results from the Population Architecture using Genomics and Epidemiology (PAGE) study. Plos Genetics. 9: e1003171. PMID 23341774 DOI: 10.1371/Journal.Pgen.1003171  1
2013 Crosslin DR, McDavid A, Weston N, Zheng X, Hart E, de Andrade M, Kullo IJ, McCarty CA, Doheny KF, Pugh E, Kho A, Hayes MG, Ritchie MD, Saip A, Crawford DC, et al. Genetic variation associated with circulating monocyte count in the eMERGE Network. Human Molecular Genetics. 22: 2119-27. PMID 23314186 DOI: 10.1093/Hmg/Ddt010  1
2013 Fesinmeyer MD, North KE, Lim U, Bůžková P, Crawford DC, Haessler J, Gross MD, Fowke JH, Goodloe R, Love SA, Graff M, Carlson CS, Kuller LH, Matise TC, Hong CP, ... Ritchie MD, et al. Effects of smoking on the genetic risk of obesity: the population architecture using genomics and epidemiology study. Bmc Medical Genetics. 14: 6. PMID 23311614 DOI: 10.1186/1471-2350-14-6  1
2013 Ritchie MD. Reducing Dimensionality in the Search for Gene-Gene Interactions Between the Lines of Genetic Code: Genetic Interactions in Understanding Disease and Complex Phenotypes. 25-37. DOI: 10.1016/B978-0-12-397017-6.00002-7  1
2012 Holzinger ER, Grady B, Ritchie MD, Ribaudo HJ, Acosta EP, Morse GD, Gulick RM, Robbins GK, Clifford DB, Daar ES, McLaren P, Haas DW. Genome-wide association study of plasma efavirenz pharmacokinetics in AIDS Clinical Trials Group protocols implicates several CYP2B6 variants. Pharmacogenetics and Genomics. 22: 858-67. PMID 23080225 DOI: 10.1097/Fpc.0B013E32835A450B  1
2012 Holzinger ER, Hulgan T, Ellis RJ, Samuels DC, Ritchie MD, Haas DW, Kallianpur AR, Bloss CS, Clifford DB, Collier AC, Gelman BB, Marra CM, McArthur JC, McCutchan JA, Morgello S, et al. Mitochondrial DNA variation and HIV-associated sensory neuropathy in CHARTER. Journal of Neurovirology. 18: 511-20. PMID 23073667 DOI: 10.1007/S13365-012-0133-Y  1
2012 Rasmussen-Torvik LJ, Pacheco JA, Wilke RA, Thompson WK, Ritchie MD, Kho AN, Muthalagu A, Hayes MG, Armstrong LL, Scheftner DA, Wilkins JT, Zuvich RL, Crosslin D, Roden DM, Denny JC, et al. High density GWAS for LDL cholesterol in African Americans using electronic medical records reveals a strong protective variant in APOE. Clinical and Translational Science. 5: 394-9. PMID 23067351 DOI: 10.1111/J.1752-8062.2012.00446.X  1
2012 Ritchie MD. The success of pharmacogenomics in moving genetic association studies from bench to bedside: Study design and implementation of precision medicine in the post-GWAS era Human Genetics. 131: 1615-1626. PMID 22923055 DOI: 10.1007/S00439-012-1221-Z  1
2012 Ritchie MD, Rowan S, Kucera G, Stubblefield T, Blair M, Carter S, Roden DM, Darbar D. Chromosome 4q25 variants are genetic modifiers of rare ion channel mutations associated with familial atrial fibrillation. Journal of the American College of Cardiology. 60: 1173-81. PMID 22818067 DOI: 10.1016/J.Jacc.2012.04.030  1
2012 Schildcrout JS, Denny JC, Bowton E, Gregg W, Pulley JM, Basford MA, Cowan JD, Xu H, Ramirez AH, Crawford DC, Ritchie MD, Peterson JF, Masys DR, Wilke RA, Roden DM. Optimizing drug outcomes through pharmacogenetics: a case for preemptive genotyping. Clinical Pharmacology and Therapeutics. 92: 235-42. PMID 22739144 DOI: 10.1038/Clpt.2012.66  1
2012 Pendergrass SA, Dudek SM, Crawford DC, Ritchie MD. Visually integrating and exploring high throughput Phenome-Wide Association Study (PheWAS) results using PheWAS-View. Biodata Mining. 5: 5. PMID 22682510 DOI: 10.1186/1756-0381-5-5  1
2012 Ding K, Shameer K, Jouni H, Masys DR, Jarvik GP, Kho AN, Ritchie MD, McCarty CA, Chute CG, Manolio TA, Kullo IJ. Genetic Loci implicated in erythroid differentiation and cell cycle regulation are associated with red blood cell traits. Mayo Clinic Proceedings. 87: 461-74. PMID 22560525 DOI: 10.1016/j.mayocp.2012.01.016  1
2012 Ellinor PT, Lunetta KL, Albert CM, Glazer NL, Ritchie MD, Smith AV, Arking DE, Müller-Nurasyid M, Krijthe BP, Lubitz SA, Bis JC, Chung MK, Dörr M, Ozaki K, Roberts JD, et al. Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nature Genetics. 44: 670-5. PMID 22544366 DOI: 10.1038/Ng.2261  1
2012 Stranger BE, Björkegren J, Dolan ME, Ritchie MD. Systems and genome-wide approaches unite to provide a route to personalized medicine. Genome Medicine. 4: 29. PMID 22494390 DOI: 10.1186/Gm328  1
2012 Fullerton SM, Wolf WA, Brothers KB, Clayton EW, Crawford DC, Denny JC, Greenland P, Koenig BA, Leppig KA, Lindor NM, McCarty CA, McGuire AL, McPeek Hinz ER, Mirel DB, Ramos EM, Ritchie MD, et al. Return of individual research results from genome-wide association studies: experience of the Electronic Medical Records and Genomics (eMERGE) Network. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 14: 424-31. PMID 22361898 DOI: 10.1038/Gim.2012.15  1
2012 Ramirez AH, Shi Y, Schildcrout JS, Delaney JT, Xu H, Oetjens MT, Zuvich RL, Basford MA, Bowton E, Jiang M, Speltz P, Zink R, Cowan J, Pulley JM, Ritchie MD, et al. Predicting warfarin dosage in European-Americans and African-Americans using DNA samples linked to an electronic health record. Pharmacogenomics. 13: 407-18. PMID 22329724 DOI: 10.2217/Pgs.11.164  1
2012 Buchanan CC, Torstenson ES, Bush WS, Ritchie MD. A comparison of cataloged variation between International HapMap Consortium and 1000 Genomes Project data. Journal of the American Medical Informatics Association : Jamia. 19: 289-94. PMID 22319179 DOI: 10.1136/Amiajnl-2011-000652  1
2012 Holzinger ER, Ritchie MD. Integrating heterogeneous high-throughput data for meta-dimensional pharmacogenomics and disease-related studies. Pharmacogenomics. 13: 213-22. PMID 22256870 DOI: 10.2217/Pgs.11.145  1
2012 Delaney JT, Ramirez AH, Bowton E, Pulley JM, Basford MA, Schildcrout JS, Shi Y, Zink R, Oetjens M, Xu H, Cleator JH, Jahangir E, Ritchie MD, Masys DR, Roden DM, et al. Predicting clopidogrel response using DNA samples linked to an electronic health record. Clinical Pharmacology and Therapeutics. 91: 257-63. PMID 22190063 DOI: 10.1038/Clpt.2011.221  1
2012 Mechanic LE, Chen HS, Amos CI, Chatterjee N, Cox NJ, Divi RL, Fan R, Harris EL, Jacobs K, Kraft P, Leal SM, McAllister K, Moore JH, Paltoo DN, Province MA, ... Ritchie MD, et al. Next generation analytic tools for large scale genetic epidemiology studies of complex diseases. Genetic Epidemiology. 36: 22-35. PMID 22147673 DOI: 10.1002/Gepi.20652  1
2012 Birdwell KA, Grady B, Choi L, Xu H, Bian A, Denny JC, Jiang M, Vranic G, Basford M, Cowan JD, Richardson DM, Robinson MP, Ikizler TA, Ritchie MD, Stein CM, et al. The use of a DNA biobank linked to electronic medical records to characterize pharmacogenomic predictors of tacrolimus dose requirement in kidney transplant recipients. Pharmacogenetics and Genomics. 22: 32-42. PMID 22108237 DOI: 10.1097/Fpc.0B013E32834E1641  1
2012 Kääb S, Crawford DC, Sinner MF, Behr ER, Kannankeril PJ, Wilde AA, Bezzina CR, Schulze-Bahr E, Guicheney P, Bishopric NH, Myerburg RJ, Schott JJ, Pfeufer A, Beckmann BM, Martens E, ... Ritchie MD, et al. A large candidate gene survey identifies the KCNE1 D85N polymorphism as a possible modulator of drug-induced torsades de pointes. Circulation. Cardiovascular Genetics. 5: 91-9. PMID 22100668 DOI: 10.1161/Circgenetics.111.960930  1
2012 Crosslin DR, McDavid A, Weston N, Nelson SC, Zheng X, Hart E, de Andrade M, Kullo IJ, McCarty CA, Doheny KF, Pugh E, Kho A, Hayes MG, Pretel S, Saip A, Ritchie MD, et al. Genetic variants associated with the white blood cell count in 13,923 subjects in the eMERGE Network. Human Genetics. 131: 639-52. PMID 22037903 DOI: 10.1007/S00439-011-1103-9  1
2012 Fesinmeyer MD, North KE, Ritchie MD, Lim U, Franceschini N, Wilkens LR, Gross MD, Bůžková P, Glenn K, Quibrera PM, Fernández-Rhodes L, Li Q, Fowke JH, Li R, Carlson CS, et al. Genetic Risk Factors for BMI and Obesity in an Ethnically Diverse Population: Results From the Population Architecture Using Genomics and Epidemiology (PAGE) Study Obesity. DOI: 10.1038/Oby.2012.158  1
2012 Buchanan CC, Wallace JR, Frase AT, Torstenson ES, Pendergrass SA, Ritchie MD. A biologically informed method for detecting associations with rare variants Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 7246: 201-210. DOI: 10.1007/978-3-642-29066-4_18  1
2012 Holzinger ER, Dudek SM, Frase AT, Fridley B, Chalise P, Ritchie MD. Comparison of methods for meta-dimensional data analysis using in silico and biological data sets Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 7246: 134-143. DOI: 10.1007/978-3-642-29066-4_12  1
2011 Haas DW, Kuritzkes DR, Ritchie MD, Amur S, Gage BF, Maartens G, Masys D, Fellay J, Phillips E, Ribaudo HJ, Freedberg KA, Petropoulos C, Manolio TA, Gulick RM, Haubrich R, et al. Pharmacogenomics of HIV therapy: summary of a workshop sponsored by the National Institute of Allergy and Infectious Diseases. Hiv Clinical Trials. 12: 277-85. PMID 22180526 DOI: 10.1310/Hct1205-277  1
2011 Zuvich RL, Armstrong LL, Bielinski SJ, Bradford Y, Carlson CS, Crawford DC, Crenshaw AT, de Andrade M, Doheny KF, Haines JL, Hayes MG, Jarvik GP, Jiang L, Kullo IJ, Li R, ... Ritchie MD, et al. Pitfalls of merging GWAS data: lessons learned in the eMERGE network and quality control procedures to maintain high data quality. Genetic Epidemiology. 35: 887-98. PMID 22125226 DOI: 10.1002/Gepi.20639  1
2011 Avery CL, He Q, North KE, Ambite JL, Boerwinkle E, Fornage M, Hindorff LA, Kooperberg C, Meigs JB, Pankow JS, Pendergrass SA, Psaty BM, Ritchie MD, Rotter JI, Taylor KD, et al. A phenomics-based strategy identifies loci on APOC1, BRAP, and PLCG1 associated with metabolic syndrome phenotype domains. Plos Genetics. 7: e1002322. PMID 22022282 DOI: 10.1371/Journal.Pgen.1002322  1
2011 Denny JC, Crawford DC, Ritchie MD, Bielinski SJ, Basford MA, Bradford Y, Chai HS, Bastarache L, Zuvich R, Peissig P, Carrell D, Ramirez AH, Pathak J, Wilke RA, Rasmussen L, et al. Variants near FOXE1 are associated with hypothyroidism and other thyroid conditions: using electronic medical records for genome- and phenome-wide studies. American Journal of Human Genetics. 89: 529-42. PMID 21981779 DOI: 10.1016/J.Ajhg.2011.09.008  1
2011 Matise TC, Ambite JL, Buyske S, Carlson CS, Cole SA, Crawford DC, Haiman CA, Heiss G, Kooperberg C, Marchand LL, Manolio TA, North KE, Peters U, Ritchie MD, Hindorff LA, et al. The Next PAGE in understanding complex traits: design for the analysis of Population Architecture Using Genetics and Epidemiology (PAGE) Study. American Journal of Epidemiology. 174: 849-59. PMID 21836165 DOI: 10.1093/Aje/Kwr160  1
2011 Grady BJ, Samuels DC, Robbins GK, Selph D, Canter JA, Pollard RB, Haas DW, Shafer R, Kalams SA, Murdock DG, Ritchie MD, Hulgan T. Mitochondrial genomics and CD4 T-cell count recovery after antiretroviral therapy initiation in AIDS clinical trials group study 384 Journal of Acquired Immune Deficiency Syndromes. 58: 363-370. PMID 21792066 DOI: 10.1097/Qai.0B013E31822C688B  1
2011 Kullo IJ, Ding K, Shameer K, McCarty CA, Jarvik GP, Denny JC, Ritchie MD, Ye Z, Crosslin DR, Chisholm RL, Manolio TA, Chute CG. Complement receptor 1 gene variants are associated with erythrocyte sedimentation rate. American Journal of Human Genetics. 89: 131-8. PMID 21700265 DOI: 10.1016/J.Ajhg.2011.05.019  1
2011 Xu H, Jiang M, Oetjens M, Bowton EA, Ramirez AH, Jeff JM, Basford MA, Pulley JM, Cowan JD, Wang X, Ritchie MD, Masys DR, Roden DM, Crawford DC, Denny JC. Facilitating pharmacogenetic studies using electronic health records and natural-language processing: a case study of warfarin. Journal of the American Medical Informatics Association : Jamia. 18: 387-91. PMID 21672908 DOI: 10.1136/Amiajnl-2011-000208  1
2011 Pendergrass SA, Brown-Gentry K, Dudek SM, Torstenson ES, Ambite JL, Avery CL, Buyske S, Cai C, Fesinmeyer MD, Haiman C, Heiss G, Hindorff LA, Hsu CN, Jackson RD, Kooperberg C, ... Ritchie MD, et al. The use of phenome-wide association studies (PheWAS) for exploration of novel genotype-phenotype relationships and pleiotropy discovery. Genetic Epidemiology. 35: 410-22. PMID 21594894 DOI: 10.1002/Gepi.20589  1
2011 Turner SD, Berg RL, Linneman JG, Peissig PL, Crawford DC, Denny JC, Roden DM, McCarty CA, Ritchie MD, Wilke RA. Knowledge-driven multi-locus analysis reveals gene-gene interactions influencing HDL cholesterol level in two independent EMR-linked biobanks Plos One. 6. PMID 21589926 DOI: 10.1371/Journal.Pone.0019586  1
2011 Bush WS, McCauley JL, DeJager PL, Dudek SM, Hafler DA, Gibson RA, Matthews PM, Kappos L, Naegelin Y, Polman CH, Hauser SL, Oksenberg J, Haines JL, Ritchie MD. A knowledge-driven interaction analysis reveals potential neurodegenerative mechanism of multiple sclerosis susceptibility. Genes and Immunity. 12: 335-40. PMID 21346779 DOI: 10.1038/Gene.2011.3  1
2011 Yaspan BL, Bush WS, Torstenson ES, Ma D, Pericak-Vance MA, Ritchie MD, Sutcliffe JS, Haines JL. Genetic analysis of biological pathway data through genomic randomization. Human Genetics. 129: 563-71. PMID 21279722 DOI: 10.1007/S00439-011-0956-2  1
2011 McCarty CA, Chisholm RL, Chute CG, Kullo IJ, Jarvik GP, Larson EB, Li R, Masys DR, Ritchie MD, Roden DM, Struewing JP, Wolf WA. The eMERGE Network: a consortium of biorepositories linked to electronic medical records data for conducting genomic studies. Bmc Medical Genomics. 4: 13. PMID 21269473 DOI: 10.1186/1755-8794-4-13  1
2011 Turner S, Armstrong LL, Bradford Y, Carlson CS, Crawford DC, Crenshaw AT, de Andrade M, Doheny KF, Haines JL, Hayes G, Jarvik G, Jiang L, Kullo IJ, Li R, Ling H, ... Ritchie MD, et al. Quality control procedures for genome-wide association studies. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. Unit1.19. PMID 21234875 DOI: 10.1002/0471142905.Hg0119S68  1
2011 Cattaert T, Calle ML, Dudek SM, Mahachie John JM, Van Lishout F, Urrea V, Ritchie MD, Van Steen K. Model-based multifactor dimensionality reduction for detecting epistasis in case-control data in the presence of noise. Annals of Human Genetics. 75: 78-89. PMID 21158747 DOI: 10.1111/J.1469-1809.2010.00604.X  1
2011 Pendergrass S, Dudek SM, Roden DM, Crawford DC, Ritchie MD. Visual integration of results from a large DNA biobank (BioVU) using synthesis-view. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 265-75. PMID 21121054  1
2011 Grady BJ, Torstenson ES, McLaren PJ, DE Bakker PI, Haas DW, Robbins GK, Gulick RM, Haubrich R, Ribaudo H, Ritchie MD. Use of biological knowledge to inform the analysis of gene-gene interactions involved in modulating virologic failure with efavirenz-containing treatment regimens in ART-naïve ACTG clinical trials participants. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 253-64. PMID 21121053 DOI: 10.1142/9789814335058_0027  1
2011 Hulgan T, Haubrich R, Riddler SA, Tebas P, Ritchie MD, McComsey GA, Haas DW, Canter JA. European mitochondrial DNA haplogroups and metabolic changes during antiretroviral therapy in AIDS Clinical Trials Group Study A5142. Aids (London, England). 25: 37-47. PMID 20871389 DOI: 10.1097/Qad.0B013E32833F9D02  1
2011 Zabaleta J, Camargo MC, Ritchie MD, Piazuelo MB, Sierra RA, Turner SD, Delgado A, Fontham ET, Schneider BG, Correa P, Ochoa AC. Association of haplotypes of inflammation-related genes with gastric preneoplastic lesions in African Americans and Caucasians. International Journal of Cancer. Journal International Du Cancer. 128: 668-75. PMID 20473875 DOI: 10.1002/Ijc.25385  1
2011 Holzinger ER, Dudek SM, Torstenson EC, Ritchie MD. ATHENA optimization: The effect of initial parameter settings across different genetic models Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 6623: 48-58. DOI: 10.1007/978-3-642-20389-3_5  1
2010 Pendergrass SA, Dudek SM, Crawford DC, Ritchie MD. Synthesis-View: visualization and interpretation of SNP association results for multi-cohort, multi-phenotype data and meta-analysis. Biodata Mining. 3: 10. PMID 21162740 DOI: 10.1186/1756-0381-3-10  1
2010 Holzinger ER, Buchanan CC, Dudek SM, Torstenson EC, Turner SD, Ritchie MD. Initialization Parameter Sweep in ATHENA: Optimizing Neural Networks for Detecting Gene-Gene Interactions in the Presence of Small Main Effects. Genetic and Evolutionary Computation Conference : [Proceedings] / Sponsored by Acm Sigevo. Genetic and Evolutionary Computation Conference. 12: 203-210. PMID 21152364 DOI: 10.1145/1830483.1830519  1
2010 Denny JC, Ritchie MD, Crawford DC, Schildcrout JS, Ramirez AH, Pulley JM, Basford MA, Masys DR, Haines JL, Roden DM. Identification of genomic predictors of atrioventricular conduction: using electronic medical records as a tool for genome science. Circulation. 122: 2016-21. PMID 21041692 DOI: 10.1161/Circulationaha.110.948828  1
2010 Ritchie MD, Bush WS. Genome simulation approaches for synthesizing in silico datasets for human genomics. Advances in Genetics. 72: 1-24. PMID 21029846 DOI: 10.1016/B978-0-12-380862-2.00001-1  1
2010 Turner SD, Dudek SM, Ritchie MD. ATHENA: A knowledge-based hybrid backpropagation-grammatical evolution neural network algorithm for discovering epistasis among quantitative trait Loci. Biodata Mining. 3: 5. PMID 20875103 DOI: 10.1186/1756-0381-3-5  1
2010 Dumitrescu L, Ritchie MD, Brown-Gentry K, Pulley JM, Basford M, Denny JC, Oksenberg JR, Roden DM, Haines JL, Crawford DC. Assessing the accuracy of observer-reported ancestry in a biorepository linked to electronic medical records. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 12: 648-50. PMID 20733501 DOI: 10.1097/Gim.0B013E3181Efe2Df  1
2010 Ribaudo HJ, Liu H, Schwab M, Schaeffeler E, Eichelbaum M, Motsinger-Reif AA, Ritchie MD, Zanger UM, Acosta EP, Morse GD, Gulick RM, Robbins GK, Clifford D, Haas DW. Effect of CYP2B6, ABCB1, and CYP3A5 polymorphisms on efavirenz pharmacokinetics and treatment response: an AIDS Clinical Trials Group study. The Journal of Infectious Diseases. 202: 717-22. PMID 20662624 DOI: 10.1086/655470  1
2010 Cattaert T, Urrea V, Naj AC, De Lobel L, De Wit V, Fu M, Mahachie John JM, Shen H, Calle ML, Ritchie MD, Edwards TL, Van Steen K. FAM-MDR: a flexible family-based multifactor dimensionality reduction technique to detect epistasis using related individuals. Plos One. 5: e10304. PMID 20421984 DOI: 10.1371/Journal.Pone.0010304  1
2010 Canter JA, Robbins GK, Selph D, Clifford DB, Kallianpur AR, Shafer R, Levy S, Murdock DG, Ritchie MD, Haas DW, Hulgan T. African mitochondrial DNA subhaplogroups and peripheral neuropathy during antiretroviral therapy Journal of Infectious Diseases. 201: 1703-1707. PMID 20402593 DOI: 10.1086/652419  1
2010 Ritchie MD, Denny JC, Crawford DC, Ramirez AH, Weiner JB, Pulley JM, Basford MA, Brown-Gentry K, Balser JR, Masys DR, Haines JL, Roden DM. Robust replication of genotype-phenotype associations across multiple diseases in an electronic medical record. American Journal of Human Genetics. 86: 560-72. PMID 20362271 DOI: 10.1016/J.Ajhg.2010.03.003  1
2010 Denny JC, Ritchie MD, Basford MA, Pulley JM, Bastarache L, Brown-Gentry K, Wang D, Masys DR, Roden DM, Crawford DC. PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations. Bioinformatics (Oxford, England). 26: 1205-10. PMID 20335276 DOI: 10.1093/Bioinformatics/Btq126  1
2010 Edwards TL, Turner SD, Torstenson ES, Dudek SM, Martin ER, Ritchie MD. A general framework for formal tests of interaction after exhaustive search methods with applications to MDR and MDR-PDT. Plos One. 5: e9363. PMID 20186329 DOI: 10.1371/Journal.Pone.0009363  1
2010 Bush WS, Dudek SM, Ritchie MD. Visualizing SNP statistics in the context of linkage disequilibrium using LD-Plus. Bioinformatics (Oxford, England). 26: 578-9. PMID 20130027 DOI: 10.1093/Bioinformatics/Btp678  1
2010 Edwards TL, Torstensen E, Dudek S, Martin ER, Ritchie MD. A cross-validation procedure for general pedigrees and matched odds ratio fitness metric implemented for the multifactor dimensionality reduction pedigree disequilibrium test. Genetic Epidemiology. 34: 194-9. PMID 19697353 DOI: 10.1002/Gepi.20447  1
2010 Ritchie MD, Denny JC, Crawford DC, Ramirez AH, Weiner JB, Pulley JM, Basford MA, Brown-Gentry K, Balser JR, Masys DR, Haines JL, Roden DM. Erratum: Robust replication of genotype-phenotype associations across multiple diseases in an electronic medical record (American Journal of Human Genetics (2010) 86 (560-572)) American Journal of Human Genetics. 87. DOI: 10.1016/J.Ajhg.2010.06.018  1
2010 Turner SD, Dudek SM, Ritchie MD. Incorporating domain knowledge into evolutionary computing for discovering gene-gene interaction Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 6238: 394-403. DOI: 10.1007/978-3-642-15844-5_40  1
2009 Body SC, Collard CD, Shernan SK, Fox AA, Liu KY, Ritchie MD, Perry TE, Muehlschlegel JD, Aranki S, Donahue BS, Pretorius M, Estrada JC, Ellinor PT, Newton-Cheh C, Seidman CE, et al. Variation in the 4q25 chromosomal locus predicts atrial fibrillation after coronary artery bypass graft surgery. Circulation. Cardiovascular Genetics. 2: 499-506. PMID 20031626 DOI: 10.1161/Circgenetics.109.849075  1
2009 Bush WS, Chen G, Torstenson ES, Ritchie MD. LD-spline: mapping SNPs on genotyping platforms to genomic regions using patterns of linkage disequilibrium. Biodata Mining. 2: 7. PMID 19954552 DOI: 10.1186/1756-0381-2-7  1
2009 Bush WS, Crawford DC, Alexander C, George AL, Roden DM, Ritchie MD. Genetic variation in the rhythmonome: ethnic variation and haplotype structure in candidate genes for arrhythmias. Pharmacogenomics. 10: 1043-53. PMID 19530973 DOI: 10.2217/Pgs.09.67  1
2009 Bush WS, Dudek SM, Ritchie MD. Biofilter: a knowledge-integration system for the multi-locus analysis of genome-wide association studies. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 368-79. PMID 19209715  1
2009 Srinivasan BS, Chen J, Cheng C, Conti D, Duan S, Fridley BL, Gu X, Haines JL, Jorgenson E, Kraja A, Lasky-Su J, Li L, Rodin A, Wang D, Province M, Ritchie MD, et al. Methods for analysis in pharmacogenomics: lessons from the Pharmacogenetics Research Network Analysis Group. Pharmacogenomics. 10: 243-51. PMID 19207025 DOI: 10.2217/14622416.10.2.243  1
2009 Edwards TL, Pericak-Vance M, Gilbert JR, Haines JL, Martin ER, Ritchie MD. An association analysis of Alzheimer disease candidate genes detects an ancestral risk haplotype clade in ACE and putative multilocus association between ACE, A2M, and LRRTM3. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 150: 721-35. PMID 19105203 DOI: 10.1002/Ajmg.B.30899  1
2009 Edwards TL, Lewis K, Velez DR, Dudek S, Ritchie MD. Exploring the performance of Multifactor Dimensionality Reduction in large scale SNP studies and in the presence of genetic heterogeneity among epistatic disease models. Human Heredity. 67: 183-92. PMID 19077437 DOI: 10.1159/000181157  1
2009 Turner SD, Crawford DC, Ritchie MD. Methods for optimizing statistical analyses in pharmacogenomics research Expert Review of Clinical Pharmacology. 2: 559-570. DOI: 10.1586/ecp.09.32  1
2009 Ritchie MD. Using prior knowledge and genome-wide association to identify pathways involved in multiple sclerosis Genome Medicine. 1. DOI: 10.1186/gm65  1
2009 Turner SD, Ritchie MD, Bush WS. Conquering the needle-in-a-haystack: How correlated input variables beneficially alter the fitness landscape for neural networks Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 5483: 80-91. DOI: 10.1007/978-3-642-01184-9_8  1
2009 Haines JL, Crawford DC, Ritchie MD. A Primer in Statistical Methods in Genetics Cardiovascular Genetics and Genomics. 20-32. DOI: 10.1002/9781444311785.ch2  1
2008 Hardison NE, Fanelli TJ, Dudek SM, Reif DM, Ritchie MD, Motsinger-Reif AA. A Balanced Accuracy Fitness Function Leads to Robust Analysis using Grammatical Evolution Neural Networks in the Case of Class Imbalance. Genetic and Evolutionary Computation Conference : [Proceedings] / Sponsored by Acm Sigevo. Genetic and Evolutionary Computation Conference. 2008: 353-354. PMID 21197143 DOI: 10.1145/1389095.1389159  1
2008 Edwards TL, Wang X, Chen Q, Wormly B, Riley B, O'Neill FA, Walsh D, Ritchie MD, Kendler KS, Chen X. Interaction between interleukin 3 and dystrobrevin-binding protein 1 in schizophrenia. Schizophrenia Research. 106: 208-17. PMID 18804346 DOI: 10.1016/J.Schres.2008.07.022  1
2008 Cooper GM, Johnson JA, Langaee TY, Feng H, Stanaway IB, Schwarz UI, Ritchie MD, Stein CM, Roden DM, Smith JD, Veenstra DL, Rettie AE, Rieder MJ. A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose. Blood. 112: 1022-7. PMID 18535201 DOI: 10.1182/Blood-2008-01-134247  1
2008 Bush WS, Edwards TL, Dudek SM, McKinney BA, Ritchie MD. Alternative contingency table measures improve the power and detection of multifactor dimensionality reduction. Bmc Bioinformatics. 9: 238. PMID 18485205 DOI: 10.1186/1471-2105-9-238  1
2008 Schwarz UI, Ritchie MD, Bradford Y, Li C, Dudek SM, Frye-Anderson A, Kim RB, Roden DM, Stein CM. Genetic determinants of response to warfarin during initial anticoagulation. The New England Journal of Medicine. 358: 999-1008. PMID 18322281 DOI: 10.1056/Nejmoa0708078  1
2008 Darbar D, Kimbrough J, Jawaid A, McCray R, Ritchie MD, Roden DM. Persistent atrial fibrillation is associated with reduced risk of torsades de pointes in patients with drug-induced long QT syndrome. Journal of the American College of Cardiology. 51: 836-42. PMID 18294569 DOI: 10.1016/J.Jacc.2007.09.066  1
2008 Motsinger-Reif AA, Dudek SM, Hahn LW, Ritchie MD. Comparison of approaches for machine-learning optimization of neural networks for detecting gene-gene interactions in genetic epidemiology. Genetic Epidemiology. 32: 325-40. PMID 18265411 DOI: 10.1002/Gepi.20307  1
2008 Canter JA, Haas DW, Kallianpur AR, Ritchie MD, Robbins GK, Shafer RW, Clifford DB, Murdock DG, Hulgan T. The mitochondrial pharmacogenomics of haplogroup T: MTND2*LHON4917G and antiretroviral therapy-associated peripheral neuropathy. The Pharmacogenomics Journal. 8: 71-7. PMID 17684475 DOI: 10.1038/Sj.Tpj.6500470  1
2008 Edwards TL, Bush WS, Turner SD, Dudek SM, Torstenson ES, Schmidt M, Martin E, Ritchie MD. Generating linkage disequilibrium patterns in data simulations using genomeSIMLA Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 4973: 24-35. DOI: 10.1007/978-3-540-78757-0_3  1
2007 Bush WS, Thornton-Wells TA, Ritchie MD. Association Rule Discovery Has the Ability to Model Complex Genetic Effects. Ieee Symposium On Computational Intelligence and Data Mining Ieee Symposium On Computational Intelligence and Data Mining. 2007: 624-629. PMID 20953276 DOI: 10.1109/CIDM.2007.368934  1
2007 Ritchie MD, Motsinger AA, Bush WS, Coffey CS, Moore JH. Genetic Programming Neural Networks: A Powerful Bioinformatics Tool for Human Genetics. Applied Soft Computing. 7: 471-479. PMID 20948988 DOI: 10.1016/J.Asoc.2006.01.013  1
2007 Ritchie MD, Bartlett J, Bush WS, Edwards TL, Motsinger AA, Torstenson ES. Exploring epistasis in candidate genes for rheumatoid arthritis. Bmc Proceedings. 1: S70. PMID 18466572 DOI: 10.1186/1753-6561-1-S1-S70  1
2007 Ritchie MD, Edwards TL, Fanelli TJ, Motsinger AA. Genetic heterogeneity is not as threatening as you might think. Genetic Epidemiology. 31: 797-800. PMID 17654613 DOI: 10.1002/Gepi.20256  1
2007 Ashley-Koch AE, Jaworski J, Ma de Q, Mei H, Ritchie MD, Skaar DA, Robert Delong G, Worley G, Abramson RK, Wright HH, Cuccaro ML, Gilbert JR, Martin ER, Pericak-Vance MA. Investigation of potential gene-gene interactions between APOE and RELN contributing to autism risk. Psychiatric Genetics. 17: 221-6. PMID 17621165 DOI: 10.1097/Ypg.0B013E32809C2F75  1
2007 Motsinger AA, Haas DW, Hulgan T, Ritchie MD. Human genomic association studies: a primer for the infectious diseases specialist. The Journal of Infectious Diseases. 195: 1737-44. PMID 17492588 DOI: 10.1086/518247  1
2007 Crawford DC, Ritchie MD, Rieder MJ. Identifying the genotype behind the phenotype: A role model found in VKORC1 and its association with warfarin dosing Pharmacogenomics. 8: 487-496. PMID 17465713 DOI: 10.2217/14622416.8.5.487  1
2007 Velez DR, White BC, Motsinger AA, Bush WS, Ritchie MD, Williams SM, Moore JH. A balanced accuracy function for epistasis modeling in imbalanced datasets using multifactor dimensionality reduction. Genetic Epidemiology. 31: 306-15. PMID 17323372 DOI: 10.1002/Gepi.20211  1
2007 Nordgard SH, Ritchie MD, Jensrud SD, Motsinger AA, Alnaes GI, Lemmon G, Berg M, Geisler S, Moore JH, Lønning PE, Børresen-Dale AL, Kristensen VN. ABCB1 and GST polymorphisms associated with TP53 status in breast cancer. Pharmacogenetics and Genomics. 17: 127-36. PMID 17301692 DOI: 10.1097/Fpc.0B013E328011Abaa  1
2007 Canter JA, Summar ML, Smith HB, Rice GD, Hall LD, Ritchie MD, Motsinger AA, Christian KG, Drinkwater DC, Scholl FG, Dyer KL, Kavanaugh-McHugh AL, Barr FE. Genetic variation in the mitochondrial enzyme carbamyl-phosphate synthetase I predisposes children to increased pulmonary artery pressure following surgical repair of congenital heart defects: a validated genetic association study. Mitochondrion. 7: 204-10. PMID 17188582 DOI: 10.1016/J.Mito.2006.11.001  1
2007 Motsinger AA, Brassat D, Caillier SJ, Erlich HA, Walker K, Steiner LL, Barcellos LF, Pericak-Vance MA, Schmidt S, Gregory S, Hauser SL, Haines JL, Oksenberg JR, Ritchie MD. Complex gene-gene interactions in multiple sclerosis: a multifactorial approach reveals associations with inflammatory genes. Neurogenetics. 8: 11-20. PMID 17024427 DOI: 10.1007/S10048-006-0058-9  1
2006 Motsinger AA, Reif DM, Dudek SM, Ritchie MD. Understanding the Evolutionary Process of Grammatical Evolution Neural Networks for Feature Selection in Genetic Epidemiology. Proceedings of the ... Ieee Symposium On Computational Intelligence in Bioinformatics and Computational Biology. Ieee Symposium On Computational Intelligence in Bioinformatics and Computational Biology. 2006: 1-8. PMID 20634919 DOI: 10.1109/CIBCB.2006.330945  1
2006 Motsinger AA, Hahn LW, Dudek SM, Ryckman KK, Ritchie MD. Alternative Cross-Over Strategies and Selection Techniques for Grammatical Evolution Optimized Neural Networks. Genetic and Evolutionary Computation Conference : [Proceedings] / Sponsored by Acm Sigevo. Genetic and Evolutionary Computation Conference. 2006: 947-948. PMID 20634918 DOI: 10.1145/1143997.1144163  1
2006 De Silva MG, Hildebrand MS, Christopoulos H, Newman MR, Bell K, Ritchie M, Smyth GK, Dahl HH. Gene expression changes during step-wise differentiation of embryonic stem cells along the inner ear hair cell pathway. Acta Oto-Laryngologica. 126: 1148-57. PMID 17050306 DOI: 10.1080/00016480600702118  1
2006 Motsinger AA, Ritchie MD, Shafer RW, Robbins GK, Morse GD, Labbe L, Wilkinson GR, Clifford DB, D'Aquila RT, Johnson VA, Pollard RB, Merigan TC, Hirsch MS, Donahue JP, Kim RB, et al. Multilocus genetic interactions and response to efavirenz-containing regimens: an adult AIDS clinical trials group study. Pharmacogenetics and Genomics. 16: 837-45. PMID 17047492 DOI: 10.1097/01.Fpc.0000230413.97596.Fa  1
2006 Haas DW, Geraghty DE, Andersen J, Mar J, Motsinger AA, D'Aquila RT, Unutmaz D, Benson CA, Ritchie MD, Landay A. Immunogenetics of CD4 lymphocyte count recovery during antiretroviral therapy: An AIDS Clinical Trials Group study. The Journal of Infectious Diseases. 194: 1098-107. PMID 16991084 DOI: 10.1086/507313  1
2006 Ritchie MD, Haas DW, Motsinger AA, Donahue JP, Erdem H, Raffanti S, Rebeiro P, George AL, Kim RB, Haines JL, Sterling TR. Drug transporter and metabolizing enzyme gene variants and nonnucleoside reverse-transcriptase inhibitor hepatotoxicity. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 43: 779-82. PMID 16912956 DOI: 10.1086/507101  1
2006 Kallianpur AR, Hulgan T, Canter JA, Ritchie MD, Haines JL, Robbins GK, Shafer RW, Clifford DB, Haas DW. Hemochromatosis (HFE) gene mutations and peripheral neuropathy during antiretroviral therapy. Aids (London, England). 20: 1503-13. PMID 16847405 DOI: 10.1097/01.Aids.0000237366.56864.3C  1
2006 Motsinger AA, Ritchie MD, Dobrin SE. Clinical applications of whole-genome association studies: future applications at the bedside. Expert Review of Molecular Diagnostics. 6: 551-65. PMID 16824029 DOI: 10.1586/14737159.6.4.551  1
2006 Bush WS, Dudek SM, Ritchie MD. Parallel multifactor dimensionality reduction: a tool for the large-scale analysis of gene-gene interactions. Bioinformatics (Oxford, England). 22: 2173-4. PMID 16809395 DOI: 10.1093/Bioinformatics/Btl347  1
2006 Ashley-Koch AE, Mei H, Jaworski J, Ma DQ, Ritchie MD, Menold MM, Delong GR, Abramson RK, Wright HH, Hussman JP, Cuccaro ML, Gilbert JR, Martin ER, Pericak-Vance MA. An analysis paradigm for investigating multi-locus effects in complex disease: examination of three GABA receptor subunit genes on 15q11-q13 as risk factors for autistic disorder. Annals of Human Genetics. 70: 281-92. PMID 16674551 DOI: 10.1111/J.1469-1809.2006.00253.X  1
2006 Brassat D, Motsinger AA, Caillier SJ, Erlich HA, Walker K, Steiner LL, Cree BA, Barcellos LF, Pericak-Vance MA, Schmidt S, Gregory S, Hauser SL, Haines JL, Oksenberg JR, Ritchie MD. Multifactor dimensionality reduction reveals gene-gene interactions associated with multiple sclerosis susceptibility in African Americans. Genes and Immunity. 7: 310-5. PMID 16625214 DOI: 10.1038/Sj.Gene.6364299  1
2006 Sanada H, Yatabe J, Midorikawa S, Hashimoto S, Watanabe T, Moore JH, Ritchie MD, Williams SM, Pezzullo JC, Sasaki M, Eisner GM, Jose PA, Felder RA. Single-nucleotide polymorphisms for diagnosis of salt-sensitive hypertension. Clinical Chemistry. 52: 352-60. PMID 16439609 DOI: 10.1373/Clinchem.2005.059139  1
2006 Martin ER, Ritchie MD, Hahn L, Kang S, Moore JH. A novel method to identify gene-gene effects in nuclear families: The MDR-PDT Genetic Epidemiology. 30: 111-123. PMID 16374833 DOI: 10.1002/Gepi.20128  1
2006 Motsinger AA, Dudek SM, Hahn LW, Ritchie MD. Comparison of neural network optimization approaches for studies of human genetics Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 3907: 103-114. DOI: 10.1007/11732242_10  1
2005 Ritchie MD. Bioinformatics approaches for detecting gene-gene and gene-environment interactions in studies of human disease Neurosurgical Focus. 19. PMID 16241104 DOI: 10.3171/Foc.2005.19.4.3  1
2005 Hulgan T, Haas DW, Haines JL, Ritchie MD, Robbins GK, Shafer RW, Clifford DB, Kallianpur AR, Summar M, Canter JA. Mitochondrial haplogroups and peripheral neuropathy during antiretroviral therapy: an adult AIDS clinical trials group study. Aids (London, England). 19: 1341-9. PMID 16103764 DOI: 10.1097/01.Aids.0000180786.02930.A1  1
2005 Ma DQ, Whitehead PL, Menold MM, Martin ER, Ashley-Koch AE, Mei H, Ritchie MD, Delong GR, Abramson RK, Wright HH, Cuccaro ML, Hussman JP, Gilbert JR, Pericak-Vance MA. Identification of significant association and gene-gene interaction of GABA receptor subunit genes in autism. American Journal of Human Genetics. 77: 377-88. PMID 16080114 DOI: 10.1086/433195  1
2005 Wilke RA, Carrillo MW, Ritchie MD. Pacific Symposium on Biocomputing--computational approaches for pharmacogenomics. Pharmacogenomics. 6: 111-3. PMID 15882130 DOI: 10.1517/14622416.6.2.111  1
2005 Bush WS, Motsinger AA, Dudek SM, Ritchie MD. Can neural network constraints in GP provide power to detect genes associated with human disease Lecture Notes in Computer Science. 44-53. DOI: 10.1007/978-3-540-32003-6_5  1
2004 Moore JH, Hahn LW, Ritchie MD, Thornton TA, White BC. Routine Discovery of Complex Genetic Models using Genetic Algorithms. Applied Soft Computing. 4: 79-86. PMID 20948983 DOI: 10.1016/J.Asoc.2003.08.003  1
2004 Vanhoose AM, Ritchie MD, Winder DG. Regulation of cAMP levels in area CA1 of hippocampus by Gi/o-coupled receptors is stimulus dependent in mice. Neuroscience Letters. 370: 80-3. PMID 15489022 DOI: 10.1016/J.Neulet.2004.07.093  1
2004 Shin NY, Dise RS, Schneider-Mergener J, Ritchie MD, Kilkenny DM, Hanks SK. Subsets of the major tyrosine phosphorylation sites in Crk-associated substrate (CAS) are sufficient to promote cell migration. The Journal of Biological Chemistry. 279: 38331-7. PMID 15247284 DOI: 10.1074/Jbc.M404675200  1
2004 Williams SM, Ritchie MD, Phillips JA, Dawson E, Prince M, Dzhura E, Willis A, Semenya A, Summar M, White BC, Addy JH, Kpodonu J, Wong LJ, Felder RA, Jose PA, et al. Multilocus analysis of hypertension: a hierarchical approach. Human Heredity. 57: 28-38. PMID 15133310 DOI: 10.1159/000077387  1
2004 Cho YM, Ritchie MD, Moore JH, Park JY, Lee KU, Shin HD, Lee HK, Park KS. Multifactor-dimensionality reduction shows a two-locus interaction associated with Type 2 diabetes mellitus Diabetologia. 47: 549-554. PMID 14730379 DOI: 10.1007/S00125-003-1321-3  1
2003 Moore JH, Thornton TA, Ritchie MD. Basic statistics. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. Appendix 3M. PMID 18428338 DOI: 10.1002/0471142905.Hga03Ms37  1
2003 Ritchie MD, White BC, Parker JS, Hahn LW, Moore JH. Optimization of neural network architecture using genetic programming improves detection and modeling of gene-gene interactions in studies of human diseases. Bmc Bioinformatics. 4: 28. PMID 12846935 DOI: 10.1186/1471-2105-4-28  1
2002 Donaldson JC, Dise RS, Ritchie MD, Hanks SK. Nephrocystin-conserved domains involved in targeting to epithelial cell-cell junctions, interaction with filamins, and establishing cell polarity. The Journal of Biological Chemistry. 277: 29028-35. PMID 12006559 DOI: 10.1074/Jbc.M111697200  1
2001 Ritchie MD, Hahn LW, Roodi N, Bailey LR, Dupont WD, Parl FF, Moore JH. Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer American Journal of Human Genetics. 69: 138-147. PMID 11404819 DOI: 10.1086/321276  1
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