| Year |
Citation |
Score |
| 2022 |
Saward B, Leissing T, Clifton I, Tumber A, Timperley C, Hopkinson R, Schofield C. Biochemical and structural insights into FIH-catalysed hydroxylation of transient receptor potential ankyrin repeat domains. Chembiochem : a European Journal of Chemical Biology. PMID 36448355 DOI: 10.1002/cbic.202200576 |
0.441 |
|
| 2022 |
Reinbold R, Hvinden IC, Rabe P, Herold RA, Finch A, Wood J, Morgan M, Staudt M, Clifton IJ, Armstrong FA, McCullagh JSO, Redmond J, Bardella C, Abboud MI, Schofield CJ. Resistance to the isocitrate dehydrogenase 1 mutant inhibitor ivosidenib can be overcome by alternative dimer-interface binding inhibitors. Nature Communications. 13: 4785. PMID 35970853 DOI: 10.1038/s41467-022-32436-4 |
0.429 |
|
| 2022 |
Rabe P, Walla CC, Goodyear NK, Welsh J, Southwart R, Clifton I, Linyard JDS, Tumber A, Claridge TDW, Myers WK, Schofield CJ. Spectroscopic studies reveal details of substrate-induced conformational changes distant from the active site in isopenicillin N synthase. The Journal of Biological Chemistry. 102249. PMID 35835215 DOI: 10.1016/j.jbc.2022.102249 |
0.432 |
|
| 2021 |
Rabe P, Kamps JJAG, Sutherlin KD, Linyard JDS, Aller P, Pham CC, Makita H, Clifton I, McDonough MA, Leissing TM, Shutin D, Lang PA, Butryn A, Brem J, Gul S, et al. X-ray free-electron laser studies reveal correlated motion during isopenicillin synthase catalysis. Science Advances. 7. PMID 34417180 DOI: 10.1126/sciadv.abh0250 |
0.599 |
|
| 2017 |
Yeh TL, Leissing TM, Abboud MI, Thinnes CC, Atasoylu O, Holt-Martyn JP, Zhang D, Tumber A, Lippl K, Lohans CT, Leung IKH, Morcrette H, Clifton IJ, Claridge TDW, Kawamura A, et al. Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials. Chemical Science. 8: 7651-7668. PMID 29435217 DOI: 10.1039/C7Sc02103H |
0.783 |
|
| 2017 |
McNeill L, Brown T, Sami M, Clifton I, Burzlaff N, Claridge T, Adlington R, Baldwin J, Rutledge PJ, Schofield C. Terminally truncated isopenicillin N synthase generates a dithioester product: evidence for a thioaldehyde intermediate and a new mode of reaction for non-heme iron oxidases. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28703303 DOI: 10.1002/Chem.201701592 |
0.595 |
|
| 2017 |
Lohans CT, Wang DY, Jorgensen C, Cahill ST, Clifton IJ, McDonough MA, Oswin HP, Spencer J, Domene C, Claridge TDW, Brem J, Schofield CJ. (13)C-Carbamylation as a mechanistic probe for the inhibition of class D β-lactamases by avibactam and halide ions. Organic & Biomolecular Chemistry. PMID 28678295 DOI: 10.1039/C7Ob01514C |
0.75 |
|
| 2017 |
Li GB, Brem J, Lesniak R, Abboud MI, Lohans CT, Clifton IJ, Yang SY, Jiménez-Castellanos JC, Avison MB, Spencer J, McDonough MA, Schofield CJ. Crystallographic analyses of isoquinoline complexes reveal a new mode of metallo-β-lactamase inhibition. Chemical Communications (Cambridge, England). PMID 28470248 DOI: 10.1039/C7Cc02394D |
0.756 |
|
| 2016 |
Brem J, Cain R, Cahill S, McDonough MA, Clifton IJ, Jiménez-Castellanos JC, Avison MB, Spencer J, Fishwick CW, Schofield CJ. Structural basis of metallo-β-lactamase, serine-β-lactamase and penicillin-binding protein inhibition by cyclic boronates. Nature Communications. 7: 12406. PMID 27499424 DOI: 10.1038/Ncomms12406 |
0.606 |
|
| 2015 |
Aik WS, Chowdhury R, Clifton IJ, Hopkinson RJ, Leissing T, McDonough MA, Nowak R, Schofield CJ, Walport LJ. Introduction to structural studies on 2-oxoglutarate-dependent oxygenases and related enzymes Rsc Metallobiology. 2015: 59-94. DOI: 10.1039/9781782621959-00059 |
0.698 |
|
| 2014 |
Chowdhury R, Sekirnik R, Brissett NC, Krojer T, Ho CH, Ng SS, Clifton IJ, Ge W, Kershaw NJ, Fox GC, Muniz JR, Vollmar M, Phillips C, Pilka ES, Kavanagh KL, et al. Ribosomal oxygenases are structurally conserved from prokaryotes to humans. Nature. 510: 422-6. PMID 24814345 DOI: 10.1038/Nature13263 |
0.716 |
|
| 2013 |
Clifton IJ, Ge W, Adlington RM, Baldwin JE, Rutledge PJ. The crystal structure of an isopenicillin N synthase complex with an ethereal substrate analogue reveals water in the oxygen binding site Febs Letters. 587: 2705-2709. PMID 23860486 DOI: 10.1016/J.Febslet.2013.07.016 |
0.454 |
|
| 2013 |
Daruzzaman A, Clifton IJ, Adlington RM, Baldwin JE, Rutledge PJ. The Interaction of Isopenicillin N Synthase with Homologated Substrate Analogues δ-(L-α-Aminoadipoyl)-L-homocysteinyl-D-Xaa Characterised by Protein Crystallography Chembiochem. 14: 599-606. PMID 23468426 DOI: 10.1002/Cbic.201200728 |
0.409 |
|
| 2013 |
Daruzzaman A, Clifton IJ, Adlington RM, Baldwin JE, Rutledge PJ. The crystal structure of isopenicillin N synthase with a dipeptide substrate analogue Archives of Biochemistry and Biophysics. 530: 48-53. PMID 23262315 DOI: 10.1016/J.Abb.2012.12.012 |
0.438 |
|
| 2011 |
Clifton IJ, Ge W, Adlington RM, Baldwin JE, Rutledge PJ. The crystal structure of isopenicillin N synthase with δ-(l-α- aminoadipoyl)-l-cysteinyl-d-methionine reveals thioether coordination to iron Archives of Biochemistry and Biophysics. 516: 103-107. PMID 22001738 DOI: 10.1016/J.Abb.2011.09.014 |
0.471 |
|
| 2011 |
Iqbal A, Clifton IJ, Chowdhury R, Ivison D, Domene C, Schofield CJ. Structural and biochemical analyses reveal how ornithine acetyl transferase binds acidic and basic amino acid substrates. Organic & Biomolecular Chemistry. 9: 6219-25. PMID 21796301 DOI: 10.1039/C1Ob05554B |
0.612 |
|
| 2011 |
Clifton IJ, Ge W, Adlington RM, Baldwin JE, Rutledge PJ. Isopenicillin N Synthase Binds δ-(L-α-Aminoadipoyl)-L-Cysteinyl-D-Thia-allo-Isoleucine through both Sulfur Atoms Chembiochem. 12: 1881-1885. PMID 21678539 DOI: 10.1002/Cbic.201100149 |
0.463 |
|
| 2011 |
Chowdhury R, Flashman E, Mecinović J, Kramer HB, Kessler BM, Frapart YM, Boucher JL, Clifton IJ, McDonough MA, Schofield CJ. Studies on the reaction of nitric oxide with the hypoxia-inducible factor prolyl hydroxylase domain 2 (EGLN1). Journal of Molecular Biology. 410: 268-79. PMID 21601578 DOI: 10.1016/J.Jmb.2011.04.075 |
0.676 |
|
| 2011 |
Chowdhury R, Yeoh KK, Tian YM, Hillringhaus L, Bagg EA, Rose NR, Leung IK, Li XS, Woon EC, Yang M, McDonough MA, King ON, Clifton IJ, Klose RJ, Claridge TD, et al. The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases. Embo Reports. 12: 463-9. PMID 21460794 DOI: 10.1038/Embor.2011.43 |
0.689 |
|
| 2010 |
McDonough MA, Loenarz C, Chowdhury R, Clifton IJ, Schofield CJ. Structural studies on human 2-oxoglutarate dependent oxygenases. Current Opinion in Structural Biology. 20: 659-72. PMID 20888218 DOI: 10.1016/J.Sbi.2010.08.006 |
0.787 |
|
| 2010 |
Conejo-Garcia A, McDonough MA, Loenarz C, McNeill LA, Hewitson KS, Ge W, Liénard BM, Schofield CJ, Clifton IJ. Structural basis for binding of cyclic 2-oxoglutarate analogues to factor-inhibiting hypoxia-inducible factor. Bioorganic & Medicinal Chemistry Letters. 20: 6125-8. PMID 20822901 DOI: 10.1016/J.Bmcl.2010.08.032 |
0.769 |
|
| 2010 |
Ge W, Clifton IJ, Stok JE, Adlington RM, Baldwin JE, Rutledge PJ. Crystallographic studies on the binding of selectively deuterated LLD- and LLL-substrate epimers by isopenicillin N synthase Biochemical and Biophysical Research Communications. 398: 659-664. PMID 20603104 DOI: 10.1016/J.Bbrc.2010.06.129 |
0.443 |
|
| 2010 |
Rose NR, Woon EC, Kingham GL, King ON, Mecinović J, Clifton IJ, Ng SS, Talib-Hardy J, Oppermann U, McDonough MA, Schofield CJ. Selective inhibitors of the JMJD2 histone demethylases: combined nondenaturing mass spectrometric screening and crystallographic approaches. Journal of Medicinal Chemistry. 53: 1810-8. PMID 20088513 DOI: 10.1021/Jm901680B |
0.776 |
|
| 2010 |
Ge W, Clifton IJ, Stok JE, Adlington RM, Baldwin JE, Rutledge PJ. The crystal structure of an LLL-configured depsipeptide substrate analogue bound to isopenicillin N synthase Organic and Biomolecular Chemistry. 8: 122-127. PMID 20024142 DOI: 10.1039/B910170E |
0.508 |
|
| 2010 |
Iqbal A, Arunlanantham H, Brown T, Chowdhury R, Clifton IJ, Kershaw NJ, Hewitson KS, McDonough MA, Schofield CJ. Crystallographic and mass spectrometric analyses of a tandem GNAT protein from the clavulanic acid biosynthesis pathway. Proteins. 78: 1398-407. PMID 20014241 DOI: 10.1002/Prot.22653 |
0.709 |
|
| 2009 |
Ge W, Clifton IJ, Howard-Jones AR, Stok JE, Adlington RM, Baldwin JE, Rutledge PJ. Structural studies on the reaction of isopenicillin N synthase with a sterically demanding depsipeptide substrate analogue Chembiochem. 10: 2025-2031. PMID 19598184 DOI: 10.1002/Cbic.200900080 |
0.473 |
|
| 2009 |
Iqbal A, Clifton IJ, Bagonis M, Kershaw NJ, Domene C, Claridge TD, Wharton CW, Schofield CJ. Anatomy of a simple acyl intermediate in enzyme catalysis: combined biophysical and modeling studies on ornithine acetyl transferase. Journal of the American Chemical Society. 131: 749-57. PMID 19105697 DOI: 10.1021/Ja807215U |
0.488 |
|
| 2008 |
Ge W, Clifton IJ, Stok JE, Adlington RM, Baldwin JE, Rutledge PJ. Isopenicillin N synthase mediates thiolate oxidation to sulfenate in a depsipeptide substrate analogue: Implications for oxygen binding and a link to nitrile hydratase? Journal of the American Chemical Society. 130: 10096-10102. PMID 18620394 DOI: 10.1021/Ja8005397 |
0.507 |
|
| 2008 |
Hamed RB, Batchelar ET, Clifton IJ, Schofield CJ. Mechanisms and structures of crotonase superfamily enzymes--how nature controls enolate and oxyanion reactivity. Cellular and Molecular Life Sciences : Cmls. 65: 2507-27. PMID 18470480 DOI: 10.1007/S00018-008-8082-6 |
0.658 |
|
| 2007 |
Stewart AC, Clifton IJ, Adlington RM, Baldwin JE, Rutledge PJ. A cyclobutanone analogue mimics penicillin in binding to isopenicillin N synthase Chembiochem. 8: 2003-2007. PMID 17907118 DOI: 10.1002/Cbic.200700176 |
0.465 |
|
| 2007 |
Howard-Jones AR, Elkins JM, Clifton IJ, Roach PL, Adlington RM, Baldwin JE, Rutledge PJ. Interactions of isopenicillin N synthase with cyclopropyl-containing substrate analogues reveal new mechanistic insight Biochemistry. 46: 4755-4762. PMID 17397141 DOI: 10.1021/Bi062314Q |
0.441 |
|
| 2007 |
Hewitson KS, Liénard BM, McDonough MA, Clifton IJ, Butler D, Soares AS, Oldham NJ, McNeill LA, Schofield CJ. Structural and mechanistic studies on the inhibition of the hypoxia-inducible transcription factor hydroxylases by tricarboxylic acid cycle intermediates. The Journal of Biological Chemistry. 282: 3293-301. PMID 17135241 DOI: 10.1074/Jbc.M608337200 |
0.663 |
|
| 2006 |
McDonough MA, Li V, Flashman E, Chowdhury R, Mohr C, Liénard BM, Zondlo J, Oldham NJ, Clifton IJ, Lewis J, McNeill LA, Kurzeja RJ, Hewitson KS, Yang E, Jordan S, et al. Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2). Proceedings of the National Academy of Sciences of the United States of America. 103: 9814-9. PMID 16782814 DOI: 10.1073/Pnas.0601283103 |
0.713 |
|
| 2006 |
Clifton IJ, McDonough MA, Ehrismann D, Kershaw NJ, Granatino N, Schofield CJ. Structural studies on 2-oxoglutarate oxygenases and related double-stranded beta-helix fold proteins. Journal of Inorganic Biochemistry. 100: 644-69. PMID 16513174 DOI: 10.1016/J.Jinorgbio.2006.01.024 |
0.637 |
|
| 2006 |
Daruzzaman A, Clifton IJ, Adlington RM, Baldwin JE, Rutledge PJ. Unexpected oxidation of a depsipeptide substrate analogue in crystalline isopenicillin N synthase Chembiochem. 7: 351-358. PMID 16444759 DOI: 10.1002/Cbic.200500282 |
0.496 |
|
| 2005 |
McNeill LA, Flashman E, Buck MR, Hewitson KS, Clifton IJ, Jeschke G, Claridge TD, Ehrismann D, Oldham NJ, Schofield CJ. Hypoxia-inducible factor prolyl hydroxylase 2 has a high affinity for ferrous iron and 2-oxoglutarate. Molecular Biosystems. 1: 321-4. PMID 16880998 DOI: 10.1039/B511249B |
0.426 |
|
| 2005 |
Howard-Jones AR, Rutledge PJ, Clifton IJ, Adlington RM, Baldwin JE. Unique binding of a non-natural L,L,L-substrate by isopenicillin N synthase Biochemical and Biophysical Research Communications. 336: 702-708. PMID 16143309 DOI: 10.1016/J.Bbrc.2005.08.155 |
0.362 |
|
| 2005 |
Welford RW, Clifton IJ, Turnbull JJ, Wilson SC, Schofield CJ. Structural and mechanistic studies on anthocyanidin synthase catalysed oxidation of flavanone substrates: the effect of C-2 stereochemistry on product selectivity and mechanism. Organic & Biomolecular Chemistry. 3: 3117-26. PMID 16106293 DOI: 10.1039/B507153D |
0.432 |
|
| 2005 |
Long AJ, Clifton IJ, Roach PL, Baldwin JE, Rutledge PJ, Schofield CJ. Structural studies on the reaction of isopenicillin N synthase with the truncated substrate analogues delta-(L-alpha-aminoadipoyl)-L-cysteinyl-glycine and delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-alanine. Biochemistry. 44: 6619-28. PMID 15850395 DOI: 10.1021/Bi047478Q |
0.565 |
|
| 2004 |
Zhang Z, Ren JS, Clifton IJ, Schofield CJ. Crystal structure and mechanistic implications of 1-aminocyclopropane-1-carboxylic acid oxidase--the ethylene-forming enzyme. Chemistry & Biology. 11: 1383-94. PMID 15489165 DOI: 10.1016/J.Chembiol.2004.08.012 |
0.491 |
|
| 2004 |
Grummitt AR, Rutledge PJ, Clifton IJ, Baldwin JE. Active-site-mediated elimination of hydrogen fluoride from a fluorinated substrate analogue by isopenicillin N synthase. The Biochemical Journal. 382: 659-66. PMID 15175003 DOI: 10.1042/Bj20040529 |
0.457 |
|
| 2003 |
Elkins JM, Rutledge PJ, Burzlaff NI, Clifton IJ, Adlington RM, Roach PL, Baldwin JE. Crystallographic studies on the reaction of isopenicillin N synthase with an unsaturated substrate analogue. Organic & Biomolecular Chemistry. 1: 1455-60. PMID 12926272 DOI: 10.1039/B212270G |
0.458 |
|
| 2003 |
Long AJ, Clifton IJ, Roach PL, Baldwin JE, Schofield CJ, Rutledge PJ. Structural studies on the reaction of isopenicillin N synthase with the substrate analogue delta-(l-alpha-aminoadipoyl)-l-cysteinyl-d-alpha-aminobutyrate. The Biochemical Journal. 372: 687-93. PMID 12622704 DOI: 10.1042/Bj20021627 |
0.546 |
|
| 2003 |
Clifton IJ, Doan LX, Sleeman MC, Topf M, Suzuki H, Wilmouth RC, Schofield CJ. Crystal structure of carbapenem synthase (CarC). The Journal of Biological Chemistry. 278: 20843-50. PMID 12611886 DOI: 10.1074/Jbc.M213054200 |
0.495 |
|
| 2003 |
Elkins JM, Rutledge PJ, Burzlaff NI, Clifton IJ, Adlington RM, Roach PL, Baldwin JE. Crystallographic studies on the reaction of isopenicillin N synthase with an unsaturated substrate analogue Organic and Biomolecular Chemistry. 1: 1455-1460. DOI: 10.1039/b212270g |
0.381 |
|
| 2002 |
Zhang Z, Ren Js, Harlos K, McKinnon CH, Clifton IJ, Schofield CJ. Crystal structure of a clavaminate synthase-Fe(II)-2-oxoglutarate-substrate-NO complex: evidence for metal centered rearrangements. Febs Letters. 517: 7-12. PMID 12062399 DOI: 10.1016/S0014-5793(02)02520-6 |
0.432 |
|
| 2002 |
Elkins JM, Clifton IJ, Hernández H, Doan LX, Robinson CV, Schofield CJ, Hewitson KS. Oligomeric structure of proclavaminic acid amidino hydrolase: evolution of a hydrolytic enzyme in clavulanic acid biosynthesis. The Biochemical Journal. 366: 423-34. PMID 12020346 DOI: 10.1042/Bj20020125 |
0.502 |
|
| 2002 |
Elkins JM, Ryle MJ, Clifton IJ, Dunning Hotopp JC, Lloyd JS, Burzlaff NI, Baldwin JE, Hausinger RP, Roach PL. X-ray crystal structure of Escherichia coli taurine/alpha-ketoglutarate dioxygenase complexed to ferrous iron and substrates. Biochemistry. 41: 5185-92. PMID 11955067 DOI: 10.1021/Bi016014E |
0.497 |
|
| 2002 |
Wilmouth RC, Turnbull JJ, Welford RW, Clifton IJ, Prescott AG, Schofield CJ. Structure and mechanism of anthocyanidin synthase from Arabidopsis thaliana. Structure (London, England : 1993). 10: 93-103. PMID 11796114 DOI: 10.1016/S0969-2126(01)00695-5 |
0.479 |
|
| 2002 |
Wilmouth RC, Edman K, Neutze R, Wright PA, Clifton IJ, Schneider TR, Schofield CJ, Hajdu J. Snapshots of serine protease catalysis: unravelling the mechanism of deacylation Acta Crystallographica Section a Foundations of Crystallography. 58: c27-c27. DOI: 10.1107/S010876730208618X |
0.39 |
|
| 2001 |
Ogle JM, Clifton IJ, Rutledge PJ, Elkins JM, Burzlaff NI, Adlington RM, Roach PL, Baldwin JE. Alternative oxidation by isopenicillin N synthase observed by X-ray diffraction. Chemistry & Biology. 8: 1231-7. PMID 11755401 DOI: 10.1016/S1074-5521(01)00090-4 |
0.46 |
|
| 2001 |
Clifton IJ, Hsueh LC, Baldwin JE, Harlos K, Schofield CJ. Structure of proline 3-hydroxylase. Evolution of the family of 2-oxoglutarate dependent oxygenases. European Journal of Biochemistry / Febs. 268: 6625-36. PMID 11737217 DOI: 10.1046/J.0014-2956.2001.02617.X |
0.604 |
|
| 2001 |
Mukherji M, Chien W, Kershaw NJ, Clifton IJ, Schofield CJ, Wierzbicki AS, Lloyd MD. Structure-function analysis of phytanoyl-CoA 2-hydroxylase mutations causing Refsum's disease. Human Molecular Genetics. 10: 1971-82. PMID 11555634 DOI: 10.1093/Hmg/10.18.1971 |
0.427 |
|
| 2001 |
Wilmouth RC, Edman K, Neutze R, Wright PA, Clifton IJ, Schneider TR, Schofield CJ, Hajdu J. X-ray snapshots of serine protease catalysis reveal a tetrahedral intermediate. Nature Structural Biology. 8: 689-94. PMID 11473259 DOI: 10.1038/90401 |
0.438 |
|
| 2001 |
Wright PA, Wilmouth RC, Clifton IJ, Schofield CJ. Kinetic and crystallographic analysis of complexes formed between elastase and peptides from beta-casein. European Journal of Biochemistry / Febs. 268: 2969-74. PMID 11358514 DOI: 10.1046/J.1432-1327.2001.02186.X |
0.426 |
|
| 2001 |
Lee HJ, Lloyd MD, Harlos K, Clifton IJ, Baldwin JE, Schofield CJ. Kinetic and crystallographic studies on deacetoxycephalosporin C synthase (DAOCS). Journal of Molecular Biology. 308: 937-48. PMID 11352583 DOI: 10.1006/Jmbi.2001.4649 |
0.563 |
|
| 2001 |
Lee HJ, Lloyd MD, Clifton IJ, Harlos K, Dubus A, Baldwin JE, Frere JM, Schofield CJ. Alteration of the co-substrate selectivity of deacetoxycephalosporin C synthase. The role of arginine 258. The Journal of Biological Chemistry. 276: 18290-5. PMID 11279000 DOI: 10.1074/Jbc.M100085200 |
0.573 |
|
| 2000 |
Wright PA, Wilmouth RC, Clifton IJ, Schofield CJ. 'pH-jump' crystallographic analyses of gamma-lactam-porcine pancreatic elastase complexes. The Biochemical Journal. 351: 335-40. PMID 11023818 DOI: 10.1042/Bj3510335 |
0.467 |
|
| 1999 |
Burzlaff NI, Rutledge PJ, Clifton IJ, Hensgens CM, Pickford M, Adlington RM, Roach PL, Baldwin JE. The reaction cycle of isopenicillin N synthase observed by X-ray diffraction. Nature. 401: 721-4. PMID 10537113 DOI: 10.1038/44400 |
0.431 |
|
| 1998 |
Wilmouth RC, Westwood NJ, Anderson K, Brownlee W, Claridge TD, Clifton IJ, Pritchard GJ, Aplin RT, Schofield CJ. Inhibition of elastase by N-sulfonylaryl beta-lactams: anatomy of a stable acyl-enzyme complex. Biochemistry. 37: 17506-13. PMID 9860865 DOI: 10.1021/Bi9816249 |
0.629 |
|
| 1997 |
Schofield CJ, Baldwin JE, Byford MF, Clifton I, Hajdu J, Hensgens C, Roach P. Proteins of the penicillin biosynthesis pathway. Current Opinion in Structural Biology. 7: 857-64. PMID 9434907 DOI: 10.1016/S0959-440X(97)80158-3 |
0.591 |
|
| 1997 |
Roach PL, Clifton IJ, Hensgens CM, Shibata N, Schofield CJ, Hajdu J, Baldwin JE. Structure of isopenicillin N synthase complexed with substrate and the mechanism of penicillin formation. Nature. 387: 827-30. PMID 9194566 DOI: 10.1038/42990 |
0.574 |
|
| 1997 |
Wilmouth RC, Clifton IJ, Robinson CV, Roach PL, Aplin RT, Westwood NJ, Hajdu J, Schofield CJ. Structure of a specific acyl-enzyme complex formed between beta-casomorphin-7 and porcine pancreatic elastase. Nature Structural Biology. 4: 456-62. PMID 9187653 DOI: 10.1038/Nsb0697-456 |
0.611 |
|
| 1997 |
Barlow JN, Baldwin JE, Clifton IJ, Gibson E, Hensgens CM, Hajdu J, Hara T, Hassan A, John P, Lloyd MD, Roach PL, Prescott A, Robinson JK, Zhang ZH, Schofield CJ. Studies on non-haem ferrous-dependent oxygenases and oxidases. Biochemical Society Transactions. 25: 86-90. PMID 9056849 DOI: 10.1042/Bst0250086 |
0.477 |
|
| 1996 |
Roach PL, Clifton IJ, Hensgens CM, Shibata N, Long AJ, Strange RW, Hasnain SS, Schofield CJ, Baldwin JE, Hajdu J. Anaerobic crystallisation of an isopenicillin N synthase.Fe(II).substrate complex demonstrated by X-ray studies. European Journal of Biochemistry / Febs. 242: 736-40. PMID 9022704 DOI: 10.1111/J.1432-1033.1996.0736R.X |
0.505 |
|
| 1995 |
Schiffer CA, Clifton IJ, Davisson VJ, Santi DV, Stroud RM. Crystal structure of human thymidylate synthase: a structural mechanism for guiding substrates into the active site. Biochemistry. 34: 16279-87. PMID 8845352 DOI: 10.1021/Bi00050A007 |
0.304 |
|
| 1995 |
Roach PL, Clifton IJ, Fülöp V, Harlos K, Barton GJ, Hajdu J, Andersson I, Schofield CJ, Baldwin JE. Crystal structure of isopenicillin N synthase is the first from a new structural family of enzymes. Nature. 375: 700-4. PMID 7791906 DOI: 10.1038/375700A0 |
0.601 |
|
| 1995 |
Roach PL, Schofield CJ, Baldwin JE, Clifton IJ, Hajdu J. Crystallization and preliminary X-ray diffraction studies on recombinant isopenicillin N synthase from Aspergillus nidulans. Protein Science : a Publication of the Protein Society. 4: 1007-9. PMID 7663335 DOI: 10.1002/Pro.5560040521 |
0.466 |
|
| Show low-probability matches. |