Manuel A. Ortega
Affiliations: | Massachusetts Institute of Technology, Cambridge, MA, United States |
Area:
BiochemistryGoogle:
"Manuel Ortega"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Wilfred A. van der Donk | grad student | 2010-2015 | UIUC |
| Catherine L. Drennan | post-doc | 2016- | MIT |
| William W. Metcalf | post-doc | 2016-2016 | UIUC (Microtree) |
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Publications
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| Bollenbach M, Ortega M, Orman M, et al. (2020) Discovery of a Cyclic Choline Analog That Inhibits Anaerobic Choline Metabolism by Human Gut Bacteria. Acs Medicinal Chemistry Letters. 11: 1980-1985 |
| Petronikolou N, Ortega MA, Borisova SA, et al. (2019) Molecular basis of Bacillus subtilis ATCC6633 self-resistance to the phosphono-oligopeptide antibiotic rhizocticin. Acs Chemical Biology |
| Ortega MA, Cogan DP, Mukherjee S, et al. (2016) Two flavoenzymes catalyze the post-translational generation of 5-chlorotryptophan and 2-aminovinyl-cysteine during NAI-107 biosynthesis. Acs Chemical Biology |
| Ortega MA, van der Donk WA. (2016) New Insights into the Biosynthetic Logic of Ribosomally Synthesized and Post-translationally Modified Peptide Natural Products. Cell Chemical Biology. 23: 31-44 |
| Ortega MA, Hao Y, Walker MC, et al. (2016) Structure and tRNA Specificity of MibB, a Lantibiotic Dehydratase from Actinobacteria Involved in NAI-107 Biosynthesis. Cell Chemical Biology |
| Ortega MA, Hao Y, Zhang Q, et al. (2015) Structure and mechanism of the tRNA-dependent lantibiotic dehydratase NisB. Nature. 517: 509-12 |
| Zhang Q, Ortega M, Shi Y, et al. (2014) Structural investigation of ribosomally synthesized natural products by hypothetical structure enumeration and evaluation using tandem MS. Proceedings of the National Academy of Sciences of the United States of America. 111: 12031-6 |
| Ortega MA, Velásquez JE, Garg N, et al. (2014) Substrate specificity of the lanthipeptide peptidase ElxP and the oxidoreductase ElxO. Acs Chemical Biology. 9: 1718-25 |