Oleh Hornykiewicz - Publications

Affiliations: 
University of Vienna, Wien, Wien, Austria 
Area:
Dopamine, Parkinson's Disease

132 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Tong J, Rathitharan G, Meyer JH, Furukawa Y, Ang LC, Boileau I, Guttman M, Hornykiewicz O, Kish SJ. Brain monoamine oxidase B and A in human parkinsonian dopamine deficiency disorders. Brain : a Journal of Neurology. 140: 2460-2474. PMID 29050386 DOI: 10.1093/Brain/Awx172  0.507
2017 Sitte HH, Pifl C, Rajput AH, Hörtnagl H, Tong J, Lloyd GK, Kish SJ, Hornykiewicz O. Dopamine and noradrenaline, but not serotonin, in the human claustrum are greatly reduced in patients with Parkinson's disease: possible functional implications. The European Journal of Neuroscience. 45: 1356. PMID 28523903 DOI: 10.1111/ejn.13573  0.726
2017 Furukawa Y, Hornykiewicz O, Kish S. Characteristic neurochemical changes in the substantia nigra (SN) and striatum of symptomatic versus asymptomatic dopa-responsive dystonia (DRD) Journal of the Neurological Sciences. 381: 178. DOI: 10.1016/J.Jns.2017.08.515  0.331
2016 Sitte HH, Pifl C, Rajput AH, Hörtnagl H, Tong J, Lloyd GK, Kish SJ, Hornykiewicz O. Dopamine and noradrenaline, but not serotonin, in the human claustrum are greatly reduced in patients with Parkinson's disease: Possible functional implications. The European Journal of Neuroscience. PMID 27741357 DOI: 10.1111/Ejn.13435  0.755
2016 Furukawa Y, Rajput AH, Tong J, Tomizawa Y, Hornykiewicz O, Kish SJ. A marked contrast between serotonergic and dopaminergic changes in dopa-responsive dystonia. Neurology. PMID 27488599 DOI: 10.1212/Wnl.0000000000003065  0.428
2015 Tong J, Ang LC, Williams B, Furukawa Y, Fitzmaurice P, Guttman M, Boileau I, Hornykiewicz O, Kish SJ. Low levels of astroglial markers in Parkinson's disease: relationship to α-synuclein accumulation. Neurobiology of Disease. 82: 243-253. PMID 26102022 DOI: 10.1016/J.Nbd.2015.06.010  0.438
2015 Pifl C, Reither H, Hornykiewicz O. The profile of mephedrone on human monoamine transporters differs from 3,4-methylenedioxymethamphetamine primarily by lower potency at the vesicular monoamine transporter. European Journal of Pharmacology. 755: 119-26. PMID 25771452 DOI: 10.1016/J.Ejphar.2015.03.004  0.692
2014 Pifl C, Rajput A, Reither H, Blesa J, Cavada C, Obeso JA, Rajput AH, Hornykiewicz O. Is Parkinson's disease a vesicular dopamine storage disorder? Evidence from a study in isolated synaptic vesicles of human and nonhuman primate striatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 8210-8. PMID 24920625 DOI: 10.1523/Jneurosci.5456-13.2014  0.763
2013 Pifl C, Hornykiewicz O, Blesa J, Adánez R, Cavada C, Obeso JA. Reduced noradrenaline, but not dopamine and serotonin in motor thalamus of the MPTP primate: relation to severity of parkinsonism. Journal of Neurochemistry. 125: 657-62. PMID 23331162 DOI: 10.1111/Jnc.12162  0.699
2012 Pifl C, Kish SJ, Hornykiewicz O. Thalamic noradrenaline in Parkinson's disease: deficits suggest role in motor and non-motor symptoms. Movement Disorders : Official Journal of the Movement Disorder Society. 27: 1618-24. PMID 23038412 DOI: 10.1002/Mds.25109  0.671
2012 Blesa J, Pifl C, Sánchez-González MA, Juri C, García-Cabezas MA, Adánez R, Iglesias E, Collantes M, Peñuelas I, Sánchez-Hernández JJ, Rodríguez-Oroz MC, Avendaño C, Hornykiewicz O, Cavada C, Obeso JA. The nigrostriatal system in the presymptomatic and symptomatic stages in the MPTP monkey model: a PET, histological and biochemical study. Neurobiology of Disease. 48: 79-91. PMID 22677034 DOI: 10.1016/J.Nbd.2012.05.018  0.746
2011 Peneder TM, Scholze P, Berger ML, Reither H, Heinze G, Bertl J, Bauer J, Richfield EK, Hornykiewicz O, Pifl C. Chronic exposure to manganese decreases striatal dopamine turnover in human alpha-synuclein transgenic mice. Neuroscience. 180: 280-92. PMID 21333719 DOI: 10.1016/J.Neuroscience.2011.02.017  0.688
2011 Tong J, Furukawa Y, Sherwin A, Hornykiewicz O, Kish SJ. Heterogeneous intrastriatal pattern of proteins regulating axon growth in normal adult human brain. Neurobiology of Disease. 41: 458-68. PMID 21029775 DOI: 10.1016/J.Nbd.2010.10.017  0.44
2011 Ouattara B, Grégoire L, Morissette M, Gasparini F, Vranesic I, Bilbe G, Johns DR, Rajput A, Hornykiewicz O, Rajput AH, Gomez-Mancilla B, Di Paolo T. Metabotropic glutamate receptor type 5 in levodopa-induced motor complications. Neurobiology of Aging. 32: 1286-95. PMID 20036444 DOI: 10.1016/J.Neurobiolaging.2009.07.014  0.327
2010 Hornykiewicz O. A brief history of levodopa. Journal of Neurology. 257: S249-52. PMID 21080185 DOI: 10.1007/s00415-010-5741-y  0.557
2010 Peneder TM, Berger M, Scholze P, Heinze G, Bertl J, Bauer J, Hornykiewicz O, Richfield EK, Pifl C. Interaction of manganese with striatal dopamine turnover in human alpha-synuclein transgenic mice Bmc Pharmacology. 10. DOI: 10.1186/1471-2210-10-S1-A16  0.675
2009 Samadi P, Rajput A, Calon F, Grégoire L, Hornykiewicz O, Rajput AH, Di Paolo T. Metabotropic glutamate receptor II in the brains of Parkinsonian patients. Journal of Neuropathology and Experimental Neurology. 68: 374-82. PMID 19287314 DOI: 10.1097/NEN.0b013e31819cabe4  0.419
2009 Boileau I, Guttman M, Rusjan P, Adams JR, Houle S, Tong J, Hornykiewicz O, Furukawa Y, Wilson AA, Kapur S, Kish SJ. Decreased binding of the D3 dopamine receptor-preferring ligand [11C]-(+)-PHNO in drug-naive Parkinson's disease. Brain : a Journal of Neurology. 132: 1366-75. PMID 19153147 DOI: 10.1093/Brain/Awn337  0.454
2008 Hornykiewicz O. Basic research on dopamine in Parkinson's disease and the discovery of the nigrostriatal dopamine pathway: the view of an eyewitness. Neuro-Degenerative Diseases. 5: 114-7. PMID 18322366 DOI: 10.1159/000113678  0.596
2008 Rajput AH, Sitte HH, Rajput A, Fenton ME, Pifl C, Hornykiewicz O. Globus pallidus dopamine and Parkinson motor subtypes: clinical and brain biochemical correlation. Neurology. 70: 1403-10. PMID 18172064 DOI: 10.1212/01.Wnl.0000285082.18969.3A  0.744
2008 Kish SJ, Tong J, Hornykiewicz O, Rajput A, Chang LJ, Guttman M, Furukawa Y. Preferential loss of serotonin markers in caudate versus putamen in Parkinson's disease. Brain : a Journal of Neurology. 131: 120-31. PMID 17956909 DOI: 10.1093/Brain/Awm239  0.592
2007 Tong J, Hornykiewicz O, Furukawa Y, Kish SJ. Marked dissociation between high noradrenaline versus low noradrenaline transporter levels in human nucleus accumbens. Journal of Neurochemistry. 102: 1691-702. PMID 17484728 DOI: 10.1111/J.1471-4159.2007.04636.X  0.457
2006 Tong J, Hornykiewicz O, Kish SJ. Inverse relationship between brain noradrenaline level and dopamine loss in Parkinson disease: a possible neuroprotective role for noradrenaline. Archives of Neurology. 63: 1724-8. PMID 17172611 DOI: 10.1001/Archneur.63.12.1724  0.529
2006 Hornykiewicz O. The discovery of dopamine deficiency in the parkinsonian brain. Journal of Neural Transmission. Supplementum. 9-15. PMID 17017502  0.48
2006 Pifl C, Hornykiewicz O. Dopamine turnover is upregulated in the caudate/putamen of asymptomatic MPTP-treated rhesus monkeys. Neurochemistry International. 49: 519-24. PMID 16698121 DOI: 10.1016/J.Neuint.2006.03.013  0.765
2006 Tong J, Hornykiewicz O, Kish SJ. Identification of a noradrenaline-rich subdivision of the human nucleus accumbens. Journal of Neurochemistry. 96: 349-54. PMID 16336226 DOI: 10.1111/J.1471-4159.2005.03546.X  0.5
2005 Woldman I, Reither H, Kattinger A, Hornykiewicz O, Pifl C. Dopamine inhibits cell growth and cell cycle by blocking ribonucleotide reductase. Neuropharmacology. 48: 525-37. PMID 15755480 DOI: 10.1016/J.Neuropharm.2004.11.013  0.723
2004 Olanow CW, Agid Y, Mizuno Y, Albanese A, Bonuccelli U, Bonucelli U, Damier P, De Yebenes J, Gershanik O, Guttman M, Grandas F, Hallett M, Hornykiewicz O, Jenner P, Katzenschlager R, et al. Levodopa in the treatment of Parkinson's disease: current controversies. Movement Disorders : Official Journal of the Movement Disorder Society. 19: 997-1005. PMID 15372588 DOI: 10.1002/Mds.20243  0.414
2004 Rajput AH, Fenton ME, Di Paolo T, Sitte H, Pifl C, Hornykiewicz O. Human brain dopamine metabolism in levodopa-induced dyskinesia and wearing-off. Parkinsonism & Related Disorders. 10: 221-6. PMID 15120096 DOI: 10.1016/J.Parkreldis.2004.01.004  0.741
2004 Calon F, Dridi M, Hornykiewicz O, Bédard PJ, Rajput AH, Di Paolo T. Increased adenosine A2A receptors in the brain of Parkinson's disease patients with dyskinesias. Brain : a Journal of Neurology. 127: 1075-84. PMID 15033896 DOI: 10.1093/brain/awh128  0.322
2004 Pifl C, Khorchide M, Kattinger A, Reither H, Hardy J, Hornykiewicz O. alpha-Synuclein selectively increases manganese-induced viability loss in SK-N-MC neuroblastoma cells expressing the human dopamine transporter. Neuroscience Letters. 354: 34-7. PMID 14698476 DOI: 10.1016/J.Neulet.2003.09.064  0.672
2003 Calon F, Rajput AH, Hornykiewicz O, Bédard PJ, Di Paolo T. Levodopa-induced motor complications are associated with alterations of glutamate receptors in Parkinson's disease. Neurobiology of Disease. 14: 404-16. PMID 14678757 DOI: 10.1016/j.nbd.2003.07.003  0.464
2003 Haycock JW, Becker L, Ang L, Furukawa Y, Hornykiewicz O, Kish SJ. Marked disparity between age-related changes in dopamine and other presynaptic dopaminergic markers in human striatum. Journal of Neurochemistry. 87: 574-85. PMID 14535941 DOI: 10.1046/J.1471-4159.2003.02017.X  0.419
2003 Calon F, Morissette M, Rajput AH, Hornykiewicz O, Bédard PJ, Di Paolo T. Changes of GABA receptors and dopamine turnover in the postmortem brains of parkinsonians with levodopa-induced motor complications. Movement Disorders : Official Journal of the Movement Disorder Society. 18: 241-53. PMID 12621627 DOI: 10.1002/mds.10343  0.498
2002 Hornykiewicz O. L-DOPA: from a biologically inactive amino acid to a successful therapeutic agent. Amino Acids. 23: 65-70. PMID 12373520 DOI: 10.1007/s00726-001-0111-9  0.303
2002 Pifl C, Kattinger A, Reither H, Hornykiewicz O. Cellular effects of dopamine--beyond oxidative mechanisms. Parkinsonism & Related Disorders. 8: 433-7. PMID 12217632 DOI: 10.1016/S1353-8020(02)00028-7  0.68
2002 Hornykiewicz O. Dopamine miracle: from brain homogenate to dopamine replacement. Movement Disorders : Official Journal of the Movement Disorder Society. 17: 501-8. PMID 12112197 DOI: 10.1002/mds.10115  0.473
2002 Calon F, Birdi S, Rajput AH, Hornykiewicz O, Bédard PJ, Di Paolo T. Increase of preproenkephalin mRNA levels in the putamen of Parkinson disease patients with levodopa-induced dyskinesias. Journal of Neuropathology and Experimental Neurology. 61: 186-96. PMID 11853020  0.363
2001 Tekumalla PK, Calon F, Rahman Z, Birdi S, Rajput AH, Hornykiewicz O, Di Paolo T, Bédard PJ, Nestler EJ. Elevated levels of DeltaFosB and RGS9 in striatum in Parkinson's disease. Biological Psychiatry. 50: 813-6. PMID 11720701 DOI: 10.1016/S0006-3223(01)01234-3  0.55
2001 Hornykiewicz O. Dopamine and Parkinson's disease. A personal view of the past, the present, and the future. Advances in Neurology. 86: 1-11. PMID 11553966  0.43
2001 Pifl C, Zezula J, Spittler A, Kattinger A, Reither H, Caron MG, Hornykiewicz O. Antiproliferative action of dopamine and norepinephrine in neuroblastoma cells expressing the human dopamine transporter. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 1607-9. PMID 11427501 DOI: 10.1096/Fj.00-0738Fje  0.744
2000 Furukawa Y, Hornykiewicz O, Fahn S, Kish SJ. Striatal dopamine in early-onset primary torsion dystonia with the DYT1 mutation. Neurology. 54: 1193-5. PMID 10720299 DOI: 10.1212/Wnl.54.5.1193  0.422
1999 Furukawa Y, Nygaard TG, Gütlich M, Rajput AH, Pifl C, DiStefano L, Chang LJ, Price K, Shimadzu M, Hornykiewicz O, Haycock JW, Kish SJ. Striatal biopterin and tyrosine hydroxylase protein reduction in dopa-responsive dystonia. Neurology. 53: 1032-41. PMID 10496263 DOI: 10.1212/Wnl.53.5.1032  0.725
1998 Ehringer H, Hornykiewicz O. Distribution of noradrenaline and dopamine (3-hydroxytyramine) in the human brain and their behavior in diseases of the extrapyramidal system. Parkinsonism & Related Disorders. 4: 53-7. PMID 18591088 DOI: 10.1016/S1353-8020(98)00012-1  0.37
1998 Hornykiewicz O. Biochemical aspects of Parkinson's disease. Neurology. 51: S2-9. PMID 9711973  0.529
1996 Wilson JM, Levey AI, Rajput A, Ang L, Guttman M, Shannak K, Niznik HB, Hornykiewicz O, Pifl C, Kish SJ. Differential changes in neurochemical markers of striatal dopamine nerve terminals in idiopathic Parkinson's disease. Neurology. 47: 718-26. PMID 8797470 DOI: 10.1212/Wnl.47.3.718  0.748
1996 Pifl C, Hornykiewicz O, Giros B, Caron MG. Catecholamine transporters and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity: studies comparing the cloned human noradrenaline and human dopamine transporter. The Journal of Pharmacology and Experimental Therapeutics. 277: 1437-43. PMID 8667208  0.708
1995 Zhong XH, Haycock JW, Shannak K, Robitaille Y, Fratkin J, Koeppen AH, Hornykiewicz O, Kish SJ. Striatal dihydroxyphenylalanine decarboxylase and tyrosine hydroxylase protein in idiopathic Parkinson's disease and dominantly inherited olivopontocerebellar atrophy. Movement Disorders : Official Journal of the Movement Disorder Society. 10: 10-7. PMID 7885342 DOI: 10.1002/Mds.870100104  0.482
1995 Pifl C, Drobny H, Reither H, Hornykiewicz O, Singer EA. Mechanism of the dopamine-releasing actions of amphetamine and cocaine: plasmalemmal dopamine transporter versus vesicular monoamine transporter. Molecular Pharmacology. 47: 368-73. PMID 7870046  0.687
1994 Shannak K, Rajput A, Rozdilsky B, Kish S, Gilbert J, Hornykiewicz O. Noradrenaline, dopamine and serotonin levels and metabolism in the human hypothalamus: observations in Parkinson's disease and normal subjects. Brain Research. 639: 33-41. PMID 8180836 DOI: 10.1016/0006-8993(94)91761-2  0.441
1994 Hornykiewicz O, Shannak K. Brain monoamines in progressive supranuclear palsy--comparison with idiopathic Parkinson's disease. Journal of Neural Transmission. Supplementum. 42: 219-27. PMID 7964689  0.461
1994 Rajput AH, Gibb WR, Zhong XH, Shannak KS, Kish S, Chang LG, Hornykiewicz O. Dopa-responsive dystonia: pathological and biochemical observations in a case. Annals of Neurology. 35: 396-402. PMID 7908789 DOI: 10.1002/Ana.410350405  0.47
1993 Hornykiewicz O. Parkinson's disease and the adaptive capacity of the nigrostriatal dopamine system: possible neurochemical mechanisms. Advances in Neurology. 60: 140-7. PMID 8420131  0.458
1992 Kish SJ, Shannak K, Rajput A, Deck JH, Hornykiewicz O. Aging produces a specific pattern of striatal dopamine loss: implications for the etiology of idiopathic Parkinson's disease. Journal of Neurochemistry. 58: 642-8. PMID 1729408 DOI: 10.1111/J.1471-4159.1992.Tb09766.X  0.478
1992 Pifl C, Reither H, Hornykiewicz O. Functional sensitization of striatal dopamine D1 receptors in the 6-hydroxydopamine-lesioned rat. Brain Research. 572: 87-93. PMID 1535275 DOI: 10.1016/0006-8993(92)90455-I  0.713
1992 Kish SJ, Mamelak M, Slimovitch C, Dixon LM, Lewis A, Shannak K, DiStefano L, Chang LJ, Hornykiewicz O. Brain neurotransmitter changes in human narcolepsy. Neurology. 42: 229-34. PMID 1370862 DOI: 10.1212/Wnl.42.1.229  0.544
1992 Pifl C, Schingnitz G, Hornykiewicz O. Striatal and non-striatal neurotransmitter changes in MPTP-parkinsonism in rhesus monkey: the symptomatic versus the asymptomatic condition. Neurochemistry International. 20: 295S-297S. PMID 1365445 DOI: 10.1016/0197-0186(92)90255-P  0.695
1992 Pifl C, Nanoff C, Schingnitz G, Schütz W, Hornykiewicz O. Sensitization of dopamine-stimulated adenylyl cyclase in the striatum of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated rhesus monkeys and patients with idiopathic Parkinson's disease. Journal of Neurochemistry. 58: 1997-2004. PMID 1349341 DOI: 10.1111/J.1471-4159.1992.Tb10939.X  0.707
1992 Hornykiewicz O. Mechanisms of neuronal loss in Parkinson's disease: a neuroanatomical-biochemical perspective. Clinical Neurology and Neurosurgery. 94: S9-11. PMID 1320533 DOI: 10.1016/0303-8467(92)90008-Q  0.456
1991 Pifl C, Reither H, Hornykiewicz O. Lower efficacy of the dopamine D1 agonist, SKF 38393, to stimulate adenylyl cyclase activity in primate than in rodent striatum. European Journal of Pharmacology. 202: 273-6. PMID 1839386 DOI: 10.1016/0014-2999(91)90304-9  0.696
1991 Kish SJ, Du F, Parks DA, Robitaille Y, Ball MJ, Schut L, Hornykiewicz O, Schwarcz R. Quinolinic acid catabolism is increased in cerebellum of patients with dominantly inherited olivopontocerebellar atrophy. Annals of Neurology. 29: 100-4. PMID 1825460 DOI: 10.1002/Ana.410290119  0.418
1991 Pifl C, Schingnitz G, Hornykiewicz O. Effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine on the regional distribution of brain monoamines in the rhesus monkey. Neuroscience. 44: 591-605. PMID 1754053 DOI: 10.1016/0306-4522(91)90080-8  0.747
1990 Pifl C, Bertel O, Schingnitz G, Hornykiewicz O. Extrastriatal dopamine in symptomatic and asymptomatic rhesus monkeys treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Neurochemistry International. 17: 263-70. PMID 20504626 DOI: 10.1016/0197-0186(90)90148-M  0.737
1990 Kish SJ, Kleinert R, Minauf M, Gilbert J, Walter GF, Slimovitch C, Maurer E, Rezvani Y, Myers R, Hornykiewicz O. Brain neurotransmitter changes in three patients who had a fatal hyperthermia syndrome. The American Journal of Psychiatry. 147: 1358-63. PMID 2133042  0.378
1990 Kish S, Dozic S, Deck J, Shannak K, Hornykiewicz O. BRAIN NORADRENERGIC CHANGES IN A PATIENT WITH WILSONʼS DISEASE Journal of Neuropathology and Experimental Neurology. 49: 280. DOI: 10.1097/00005072-199005000-00064  0.301
1989 Hornykiewicz O. Ageing and neurotoxins as causative factors in idiopathic Parkinson's disease--a critical analysis of the neurochemical evidence. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 13: 319-28. PMID 2664888 DOI: 10.1016/0278-5846(89)90121-8  0.472
1988 Kish SJ, Shannak K, Hornykiewicz O. Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. Pathophysiologic and clinical implications. The New England Journal of Medicine. 318: 876-80. PMID 3352672 DOI: 10.1056/Nejm198804073181402  0.53
1988 Pifl C, Schingnitz G, Hornykiewicz O. The neurotoxin MPTP does not reproduce in the rhesus monkey the interregional pattern of striatal dopamine loss typical of human idiopathic Parkinson's disease. Neuroscience Letters. 92: 228-33. PMID 3263594 DOI: 10.1016/0304-3940(88)90066-3  0.756
1988 Pifl C, Hornykiewicz O. Postsynaptic dopamine agonist properties of B-HT 920 as revealed by concomitant D-1 receptor stimulation. European Journal of Pharmacology. 146: 189-91. PMID 3258244 DOI: 10.1016/0014-2999(88)90504-3  0.649
1988 Gilbert JJ, Kish SJ, Chang LJ, Morito C, Shannak K, Hornykiewicz O. Dementia, parkinsonism, and motor neuron disease: neurochemical and neuropathological correlates. Annals of Neurology. 24: 688-91. PMID 2904794 DOI: 10.1002/Ana.410240518  0.32
1988 Pifl C, Pichler L, Kobinger W, Hornykiewicz O. The dopamine autoreceptor agonist, B-HT 920, preferentially reduces brain dopamine release in vivo: biochemical indices of brain dopamine, noradrenaline and serotonin in ventriculocisternal perfusates in the cat. European Journal of Pharmacology. 153: 33-44. PMID 2463928 DOI: 10.1016/0014-2999(88)90585-7  0.667
1987 Kish S, Rajput A, Gilbert J, Rozdilsky B, Chang LJ, Shannak K, Hornykiewicz O. GABA-dopamine relationship in Parkinson's disease striatum. Advances in Neurology. 45: 75-7. PMID 3825737  0.415
1987 Pichler L, Pifl C, Hornykiewicz O, Kobinger W. The dopamine autoreceptor agonist B-HT 920 inhibits in vivo dopamine release into the cerebroventricular system of cats. European Journal of Pharmacology. 135: 239-42. PMID 2884121 DOI: 10.1016/0014-2999(87)90618-2  0.72
1987 Kish SJ, Shannak K, Hornykiewicz O. Elevated serotonin and reduced dopamine in subregionally divided Huntington's disease striatum. Annals of Neurology. 22: 386-9. PMID 2445259 DOI: 10.1002/Ana.410220318  0.524
1986 Hinzen D, Hornykiewicz O, Kobinger W, Pichler L, Pifl C, Schingnitz G. The dopamine autoreceptor agonist B-HT 920 stimulates denervated postsynaptic brain dopamine receptors in rodent and primate models of Parkinson's disease: a novel approach to treatment. European Journal of Pharmacology. 131: 75-86. PMID 3816949 DOI: 10.1016/0014-2999(86)90517-0  0.673
1986 Kish SJ, Rajput A, Gilbert J, Rozdilsky B, Chang LJ, Shannak K, Hornykiewicz O. Elevated gamma-aminobutyric acid level in striatal but not extrastriatal brain regions in Parkinson's disease: correlation with striatal dopamine loss. Annals of Neurology. 20: 26-31. PMID 2874765 DOI: 10.1002/Ana.410200106  0.37
1985 Kish SJ, Morito C, Hornykiewicz O. Glutathione peroxidase activity in Parkinson's disease brain. Neuroscience Letters. 58: 343-6. PMID 4047494 DOI: 10.1016/0304-3940(85)90078-3  0.348
1985 Hornykiewicz O. [The life history of brain dopamine]. Wiener Klinische Wochenschrift. 97: 350-4. PMID 2986364  0.527
1985 Kish SJ, Chang LJ, Mirchandani L, Shannak K, Hornykiewicz O. Progressive supranuclear palsy: relationship between extrapyramidal disturbances, dementia, and brain neurotransmitter markers. Annals of Neurology. 18: 530-6. PMID 2416269 DOI: 10.1002/Ana.410180504  0.329
1984 Kish SJ, Shannak KS, Rajput AH, Gilbert JJ, Hornykiewicz O. Cerebellar norepinephrine in patients with Parkinson's disease and control subjects. Archives of Neurology. 41: 612-4. PMID 6721735 DOI: 10.1001/Archneur.1984.04210080020007  0.341
1981 Lee T, Seeman P, Hornykiewicz O, Bilbao J, Deck J, Tourtellotte WW. Parkinson's disease: low density and presynaptic location of D3 dopamine receptors. Brain Research. 212: 494-8. PMID 7225883 DOI: 10.1016/0006-8993(81)90484-4  0.416
1981 Sperk G, Berger M, Hörtnagl H, Hornykiewicz O. Kainic acid-induced changes of serotonin and dopamine metabolism in the striatum and substantia nigra of the rat. European Journal of Pharmacology. 74: 279-86. PMID 6170518 DOI: 10.1016/0014-2999(81)90046-7  0.343
1981 Lloyd KG, Hornykiewicz O, Davidson L, Shannak K, Farley I, Goldstein M, Shibuya M, Kelley WN, Fox IH. Biochemical evidence of dysfunction of brain neurotransmitters in the Lesch-Nyhan syndrome. The New England Journal of Medicine. 305: 1106-11. PMID 6117011 DOI: 10.1056/Nejm198111053051902  0.364
1981 Sperk G, Berger M, Hornykiewicz O. Influence of kainic acid lesions on turnover of dopamine and serotonin in the striatum Naunyn-Schmiedeberg's Archives of Pharmacology. 316: 264.  0.385
1980 Hornykiewicz O. [Brain dopamine and brain disorders - and what we have learned from these studies (author's transl)]. Wiener Klinische Wochenschrift. 92: 740-3. PMID 7467350  0.451
1980 Farley IJ, Shannak KS, Hornykiewicz O. Brain monoamine changes in chronic paranoid schizophrenia and their possible relation to increased dopamine receptor sensitivity. Advances in Biochemical Psychopharmacology. 21: 427-33. PMID 6155058  0.3
1979 Fariello RG, Hornykiewicz O. Substantia nigra and pentylenetetrazol threshold in rats: correlation with striatal dopamine metabolism. Experimental Neurology. 65: 202-8. PMID 262229 DOI: 10.1016/0014-4886(79)90260-7  0.379
1978 Price KS, Farley IJ, Hornykiewicz O. Neurochemistry of Parkinson's disease: relation between striatal and limbic dopamine. Advances in Biochemical Psychopharmacology. 19: 293-300. PMID 696462  0.486
1978 Lee T, Seeman P, Rajput A, Farley IJ, Hornykiewicz O. Receptor basis for dopaminergic supersensitivity in Parkinson's disease. Nature. 273: 59-61. PMID 692671 DOI: 10.1038/273059a0  0.325
1978 Shibuya M, Fariello R, Farley IJ, Price KS, Lloyd KG, Hornykiewicz O. Cobalt injections into the substantia nigra of the rat: effects on behavior and dopamine metabolism in the striatum. Experimental Neurology. 58: 486-99. PMID 620704 DOI: 10.1016/0014-4886(78)90103-6  0.362
1978 Hornykiewicz O. Psychopharmacological implications of dopamine and dopamine antagonists: a critical evaluation of current evidence. Neuroscience. 3: 773-83. PMID 30919 DOI: 10.1016/0306-4522(78)90030-1  0.452
1977 Farley IJ, Price KS, Hornykiewicz O. Dopamine in thelimbic regions of the human brain: normal and abnormal. Advances in Biochemical Psychopharmacology. 16: 57-64. PMID 883559  0.451
1977 Hornykiewicz O. Psychopharmacological implications of dopamine and dopamine antagonists: a critical evaluation of current evidence. Annual Review of Pharmacology and Toxicology. 17: 545-59. PMID 17361 DOI: 10.1146/annurev.pa.17.040177.002553  0.452
1975 Hornykiewicz O. Parkinsonism induced by dopaminergic antagonists. Advances in Neurology. 9: 155-64. PMID 1096571  0.435
1975 Hornykiewicz O. Brain monoamines and parkinsonism. National Institute On Drug Abuse Research Monograph Series. 13-21. PMID 787796  0.468
1975 Lloyd KG, Davidson L, Hornykiewicz O. The neurochemistry of Parkinson's disease: effect of L-dopa therapy. The Journal of Pharmacology and Experimental Therapeutics. 195: 453-64. PMID 489  0.381
1975 Hornykiewicz O. Abnormalities of nigrostriatal dopamine metabolism: neurochemical, morphological and clinical correlations | NEUROPSYCHOPHARMACOLOGY. PROCEEDINGS OF THE IX CONGRESS OF THE COLLEGIUM INTERNATIONALE NEUROPSYCHOPHARMACOLOGICUM, PARIS, 7-12 JULY, 1974 Excerpta Medica, Amsterdam. 524-529.  0.346
1974 Kuschinsky K, Hornykiewicz O. Effects of morphine on striatal dopamine metabolism: possible mechanism of its opposite effect on locomotor activity in rats and mice. European Journal of Pharmacology. 26: 41-50. PMID 4598755 DOI: 10.1016/0014-2999(74)90072-7  0.323
1974 Hornykiewicz O. Some remarks concerning the possible role of brain monoamines (dopamine, noradrenaline, serotonin) in mental disorders. Journal of Psychiatric Research. 11: 249-53. PMID 4282386 DOI: 10.1016/0022-3956(74)90098-3  0.351
1974 Hornykiewicz O. Metabolism of dopamine and l-dopa in human brain Biochemical Pharmacology. 23: 917-923. DOI: 10.1016/0006-2952(74)90162-2  0.34
1973 Hornykiewicz O. Dopamine in the basal ganglia. Its role and therapeutic implications (including the clinical use of L-DOPA). British Medical Bulletin. 29: 172-8. PMID 4356552  0.348
1973 Bernheimer H, Birkmayer W, Hornykiewicz O, Jellinger K, Seitelberger F. Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological and neurochemical correlations. Journal of the Neurological Sciences. 20: 415-55. PMID 4272516 DOI: 10.1016/0022-510X(73)90175-5  0.477
1973 Hornykiewicz O. Metabolism of dopamine and L dopa in the human brain Life Sciences. 13: 1xxiv-1xxvi.  0.34
1973 Hornykiewicz O. Metabolism of dopamine and L-dopa in the human brain Life Sciences. 13: lxxiv-lxxvi.  0.34
1972 Kuschinsky K, Hornykiewicz O. Morphine catalepsy in the rat: relation to striatal dopamine metabolism. European Journal of Pharmacology. 19: 119-22. PMID 5065530  0.331
1972 Bieger D, Hornykiewicz O. Dopamine in the earthworm, Lumbricus terrestris: enhancement of rhythmic contractile activity. Neuropharmacology. 11: 745-8. PMID 4670601 DOI: 10.1016/0028-3908(72)90085-8  0.427
1972 Hornykiewicz O. Dopamine and extrapyramidal motor function and dysfunction. Research Publications - Association For Research in Nervous and Mental Disease. 50: 390-415. PMID 4561070  0.368
1971 Hornykiewicz O. Neurochemical pathology and pharmacology of brain dopamine and acetylcholine: rational basis for the current drug treatment of Parkinsonism. Contemporary Neurology Series. 8: 33-65. PMID 5162181  0.385
1971 Davidson L, Lloyd K, Dankova J, Hornykiewicz O. L-DOPA treatment in Parkinson's disease: effect on dopamine and related substances in discrete brain regions. Experientia. 27: 1048-9. PMID 5116129  0.397
1970 Hornykiewicz O. The metabolism of brain dopamine in human parkinsonism. Rivista Di Patologia Nervosa E Mentale. 91: 281-6. PMID 5525774  0.423
1968 Hornykiewicz O, Lisch HJ, Springer A. Homovanillic acid in different regions of the human brain: attempt at localizing central dopamine fibres. Brain Research. 11: 662-71. PMID 5712014  0.356
1968 Lisch HJ, Aigner A, Hornykiewicz O. [Dopamine metabolism in the rabbit caudate nucleus following partial inhibition of brain monoamine oxidase by nialamide]. Naunyn-Schmiedebergs Archiv Fã¼R Experimentelle Pathologie Und Pharmakologie. 261: 289-98. PMID 4235430  0.393
1968 Lisch H, Aigner A, Hornykiewicz O. Dopamin-Stoffwechsel im Nucleus caudatus des Kaninchens nach partieller Hemmung der Gehirn-Monoaminoxydase mittels Nialamid Naunyn-Schmiedebergs Archiv F�R Pharmakologie Und Experimentelle Pathologie. 261: 289-298. DOI: 10.1007/BF00537174  0.434
1967 Hornykiewicz O, Lisch HJ. [Monoamine oxidase inhibitors and dopamine-(3-hydroxytyramine-) metabolism in the brain]. Naunyn-Schmiedebergs Archiv Fã¼R Experimentelle Pathologie Und Pharmakologie. 257: 30. PMID 4231842  0.366
1967 Hornykiewicz O, Lisch H-. Monoaminoxydase-Hemmer und Dopamin-(3-Hydroxytyramin-) Stoffwechsel im Gehirn Naunyn-Schmiedebergs Archiv F�R Pharmakologie Und Experimentelle Pathologie. 257: 30-30. DOI: 10.1007/BF00537404  0.471
1967 Hornykiewicz O, Lisch H, Denk H. Wirkung von Chlorpromazin (CPZ) und ?-Methyl-p-Tyrosin (?MpT) auf den Dopamin-(DA) Gehalt des nigro-stri�ren Systems Naunyn-Schmiedebergs Archiv F�R Pharmakologie Und Experimentelle Pathologie. 257: 289-290. DOI: 10.1007/BF00537056  0.383
1966 Hornykiewicz O. Dopamine (3-hydroxytyramine) and brain function. Pharmacological Reviews. 18: 925-64. PMID 5328389  0.4
1965 Bernheimer H, Hornykiewicz O. [Decreased homovanillic acid concentration in the brain in parkinsonian subjects as an expression of a disorder of central dopamine metabolism]. Klinische Wochenschrift. 43: 711-5. PMID 5826380 DOI: 10.1007/BF01707066  0.31
1965 Bernheimer H, Hornykiewicz O. Wirkung von Phenothiazinderivaten auf den Dopamin-(=3-Hydroxytyramin-)Stoffwechsel im Nucleus caudatus Naunyn-Schmiedeberg's Archiv F�R Experimentelle Pathologie Und Pharmakologie. 251: 135-136. DOI: 10.1007/BF00420105  0.453
1964 Bernheimer H, Hornykiewicz O. Das Verhalten des Dopamin-Metaboliten Homovanillinsäure im Gehirn von normalen und Parkinson-kranken Menschen Naunyn-Schmiedebergs Archiv FüR Experimentelle Pathologie Und Pharmakologie. 247: 305-306. DOI: 10.1007/BF02308399  0.513
1964 Seitelberger F, Petsche H, Bernheimer H, Hornykiewicz O. Verhalten des Dopamins (=3-Hydroxytyramin) im Nucleus caudatus nach elektrischer Koagulation des Globus pallidus The Science of Nature. 51: 314-315. DOI: 10.1007/Bf00624184  0.396
1963 HORNYKIEWICZ O. [The tropical localization and content of noradrenalin and dopamine (3-hydroxytyramine) in the substantia nigra of normal persons and patients with Parkinson's disease]. Wiener Klinische Wochenschrift. 75: 309-12. PMID 13954967  0.456
1962 HORNYKIEWICZ O. [Dopamine (3-hydroxytyramine) in the central nervous system and its relation to the Parkinson syndrome in man]. Deutsche Medizinische Wochenschrift (1946). 87: 1807-10. PMID 14448985 DOI: 10.1055/s-0028-1114024  0.442
1962 Bernheimer H, Hornykiewicz O. Monoaminoxydase-Hemmer und Dopamin-, Noradrenalin- und 5-Hydroxytryptamin-Stoffwechsel im Gehirn Parkinson-kranker Menschen Naunyn-Schmiedeberg's Archiv F�R Experimentelle Pathologie Und Pharmakologie. 245: 52-52. DOI: 10.1007/BF00260041  0.526
1962 Bernheimer H, Hornykiewicz O. Das Verhalten einiger Enzyme im Gehirn normaler und Parkinson-kranker Menschen Naunyn-Schmiedeberg's Archiv F�R Experimentelle Pathologie Und Pharmakologie. 243: 295-296. DOI: 10.1007/BF00244849  0.344
1961 Hornykiewicz O, Ehringer H, Lechner K. Beeinflussung der Iproniazidwirkung auf die Katecholamine und das 5-Hydroxytryptamin des Rattenhirnes durch Chlorpromazin Naunyn-Schmiedebergs Archiv FüR Experimentelle Pathologie Und Pharmakologie. 241: 198-199. DOI: 10.1007/BF02433556  0.3
1960 EHRINGER H, HORNYKIEWICZ O. [Distribution of noradrenaline and dopamine (3-hydroxytyramine) in the human brain and their behavior in diseases of the extrapyramidal system]. Klinische Wochenschrift. 38: 1236-9. PMID 13726012 DOI: 10.1007/BF01485901  0.37
1959 HOLZER G, HORNYKIEWICZ O. [On dopamine (hydroxytyramine) metabolism in the rat brain]. Naunyn-Schmiedebergs Archiv Fã¼R Experimentelle Pathologie Und Pharmakologie. 237: 27-33. PMID 14402902  0.331
1959 Holzer G, Hornykiewicz O. �ber den Dopamin-(Hydroxytyramin-)Stoffwechsel im Gehirn der Ratte Naunyn-Schmiedeberg's Archiv F�R Experimentelle Pathologie Und Pharmakologie. 237. DOI: 10.1007/BF00244557  0.47
1958 BORN GV, HORNYKIEWICZ O, STAFFORD A. The uptake of adrenaline and noradrenaline by blood platelets of the pig. British Journal of Pharmacology and Chemotherapy. 13: 411-4. PMID 13618545  0.421
1958 HORNYKIEWICZ O, OBENAUS H. [The effect of lysergic acid diethylamide on the hypotensive effects of dopamine and adrenalin]. Wiener Klinische Wochenschrift. 70: 948-9. PMID 13616317  0.39
1957 BORN GV, HORNYKIEWICZ O. The proportionality between the uptake of adrenaline by blood platelets and their content of adenosine triphosphate. The Journal of Physiology. 136: 30P-1P. PMID 13429505  0.423
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