| Year |
Citation |
Score |
| 2024 |
Suzuki K, Hatzikotoulas K, Southam L, Taylor HJ, Yin X, Lorenz KM, Mandla R, Huerta-Chagoya A, Melloni GEM, Kanoni S, Rayner NW, Bocher O, Arruda AL, Sonehara K, Namba S, ... ... Mohlke KL, et al. Genetic drivers of heterogeneity in type 2 diabetes pathophysiology. Nature. PMID 38374256 DOI: 10.1038/s41586-024-07019-6 |
0.343 |
|
| 2024 |
Pandey GK, Vadlamudi S, Currin KW, Moxley AH, Nicholas J, McAfee JC, Broadway KA, Mohlke KL. Liver regulatory mechanisms of non-coding variants at lipid and metabolic trait loci. Hgg Advances. 100275. PMID 38297830 DOI: 10.1016/j.xhgg.2024.100275 |
0.379 |
|
| 2023 |
Varshney A, Manickam N, Orchard P, Tovar A, Zhang Z, Feng F, Erdos MR, Narisu N, Ventresca C, Nishino K, Rai V, Stringham HM, Jackson AU, Tamsen T, Gao C, ... ... Mohlke KL, et al. Population-scale skeletal muscle single-nucleus multi-omic profiling reveals extensive context specific genetic regulation. Biorxiv : the Preprint Server For Biology. PMID 38168419 DOI: 10.1101/2023.12.15.571696 |
0.321 |
|
| 2023 |
Brotman SM, Oravilahti A, Rosen JD, Alvarez M, Heinonen S, van der Kolk B, Silva LF, Perrin HJ, Vadlamudi S, Pylant C, Deochand S, Basta PV, Valone JM, Narain MN, Stringham HM, ... ... Mohlke KL, et al. Cell-type composition affects adipose gene expression associations with cardiometabolic traits. Diabetes. PMID 37647564 DOI: 10.2337/db23-0365 |
0.321 |
|
| 2023 |
Sun Q, Broadaway KA, Edmiston SN, Fajgenbaum K, Miller-Fleming T, Westerkam LL, Melendez-Gonzalez M, Bui H, Blum FR, Levitt B, Lin L, Hao H, Harris KM, Liu Z, Thomas NE, ... ... Mohlke KL, et al. Genetic Variants Associated With Hidradenitis Suppurativa. Jama Dermatology. PMID 37494057 DOI: 10.1001/jamadermatol.2023.2217 |
0.364 |
|
| 2023 |
Graham SE, Clarke SL, Wu KH, Kanoni S, Zajac GJM, Ramdas S, Surakka I, Ntalla I, Vedantam S, Winkler TW, Locke AE, Marouli E, Hwang MY, Han S, Narita A, ... ... Mohlke KL, et al. Author Correction: The power of genetic diversity in genome-wide association studies of lipids. Nature. PMID 37237109 DOI: 10.1038/s41586-023-06194-2 |
0.313 |
|
| 2023 |
Suzuki K, Hatzikotoulas K, Southam L, Taylor HJ, Yin X, Lorenz KM, Mandla R, Huerta-Chagoya A, Rayner NW, Bocher O, Ana Luiza de SVA, Sonehara K, Namba S, Lee SSK, Preuss MH, ... ... Mohlke KL, et al. Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications. Medrxiv : the Preprint Server For Health Sciences. PMID 37034649 DOI: 10.1101/2023.03.31.23287839 |
0.362 |
|
| 2022 |
Lansdon LA, Dickinson A, Arlis S, Liu H, Hlas A, Hahn A, Bonde G, Long A, Standley J, Tyryshkina A, Wehby G, Lee NR, Daack-Hirsch S, Mohlke K, Girirajan S, et al. Genome-wide analysis of copy number variation in humans with cleft lip and/or cleft palate identifies COBLL1, RIC1, and ARHGEF38 as clefting genes. American Journal of Human Genetics. PMID 36493769 DOI: 10.1016/j.ajhg.2022.11.012 |
0.347 |
|
| 2022 |
Saunders GRB, Wang X, Chen F, Jang SK, Liu M, Wang C, Gao S, Jiang Y, Khunsriraksakul C, Otto JM, Addison C, Akiyama M, Albert CM, Aliev F, Alonso A, ... ... Mohlke KL, et al. Genetic diversity fuels gene discovery for tobacco and alcohol use. Nature. PMID 36477530 DOI: 10.1038/s41586-022-05477-4 |
0.339 |
|
| 2022 |
Yengo L, Vedantam S, Marouli E, Sidorenko J, Bartell E, Sakaue S, Graff M, Eliasen AU, Jiang Y, Raghavan S, Miao J, Arias JD, Graham SE, Mukamel RE, Spracklen CN, ... ... Mohlke KL, et al. A saturated map of common genetic variants associated with human height. Nature. PMID 36224396 DOI: 10.1038/s41586-022-05275-y |
0.458 |
|
| 2022 |
Ramdas S, Judd J, Graham SE, Kanoni S, Wang Y, Surakka I, Wenz B, Clarke SL, Chesi A, Wells A, Bhatti KF, Vedantam S, Winkler TW, Locke AE, Marouli E, ... ... Mohlke KL, et al. A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids. American Journal of Human Genetics. 109: 1366-1387. PMID 35931049 DOI: 10.1016/j.ajhg.2022.06.012 |
0.352 |
|
| 2022 |
Mahajan A, Spracklen CN, Zhang W, Ng MCY, Petty LE, Kitajima H, Yu GZ, Rüeger S, Speidel L, Kim YJ, Horikoshi M, Mercader JM, Taliun D, Moon S, Kwak SH, ... ... Mohlke KL, et al. Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation. Nature Genetics. PMID 35551307 DOI: 10.1038/s41588-022-01058-3 |
0.697 |
|
| 2022 |
Loh M, Zhang W, Ng HK, Schmid K, Lamri A, Tong L, Ahmad M, Lee JJ, Ng MCY, Petty LE, Spracklen CN, Takeuchi F, Islam MT, Jasmine F, Kasturiratne A, ... ... Mohlke KL, et al. Identification of genetic effects underlying type 2 diabetes in South Asian and European populations. Communications Biology. 5: 329. PMID 35393509 DOI: 10.1038/s42003-022-03248-5 |
0.37 |
|
| 2022 |
Yin X, Chan LS, Bose D, Jackson AU, VandeHaar P, Locke AE, Fuchsberger C, Stringham HM, Welch R, Yu K, Fernandes Silva L, Service SK, Zhang D, Hector EC, Young E, ... ... Mohlke KL, et al. Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci. Nature Communications. 13: 1644. PMID 35347128 DOI: 10.1038/s41467-022-29143-5 |
0.409 |
|
| 2022 |
Brotman SM, Raulerson CK, Vadlamudi S, Currin KW, Shen Q, Parsons VA, Iyengar AK, Roman TS, Furey TS, Kuusisto J, Collins FS, Boehnke M, Laakso M, Pajukanta P, Mohlke KL. Subcutaneous adipose tissue splice quantitative trait loci reveal differences in isoform usage associated with cardiometabolic traits. American Journal of Human Genetics. 109: 66-80. PMID 34995504 DOI: 10.1016/j.ajhg.2021.11.019 |
0.37 |
|
| 2021 |
Hindy G, Dornbos P, Chaffin MD, Liu DJ, Wang M, Selvaraj MS, Zhang D, Park J, Aguilar-Salinas CA, Antonacci-Fulton L, Ardissino D, Arnett DK, Aslibekyan S, Atzmon G, Ballantyne CM, ... ... Mohlke KL, et al. Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes. American Journal of Human Genetics. PMID 34932938 DOI: 10.1016/j.ajhg.2021.11.021 |
0.354 |
|
| 2021 |
Graham SE, Clarke SL, Wu KH, Kanoni S, Zajac GJM, Ramdas S, Surakka I, Ntalla I, Vedantam S, Winkler TW, Locke AE, Marouli E, Hwang MY, Han S, Narita A, ... ... Mohlke KL, et al. The power of genetic diversity in genome-wide association studies of lipids. Nature. PMID 34887591 DOI: 10.1038/s41586-021-04064-3 |
0.389 |
|
| 2021 |
Perrin HJ, Currin KW, Vadlamudi S, Pandey GK, Ng KK, Wabitsch M, Laakso M, Love MI, Mohlke KL. Chromatin accessibility and gene expression during adipocyte differentiation identify context-dependent effects at cardiometabolic GWAS loci. Plos Genetics. 17: e1009865. PMID 34699533 DOI: 10.1371/journal.pgen.1009865 |
0.342 |
|
| 2021 |
Goodrich JK, Singer-Berk M, Son R, Sveden A, Wood J, England E, Cole JB, Weisburd B, Watts N, Caulkins L, Dornbos P, Koesterer R, Zappala Z, Zhang H, Maloney KA, ... ... Mohlke KL, et al. Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes. Nature Communications. 12: 3505. PMID 34108472 DOI: 10.1038/s41467-021-23556-4 |
0.343 |
|
| 2021 |
Chen J, Spracklen CN, Marenne G, Varshney A, Corbin LJ, Luan J, Willems SM, Wu Y, Zhang X, Horikoshi M, Boutin TS, Mägi R, Waage J, Li-Gao R, Chan KHK, ... ... Mohlke KL, et al. The trans-ancestral genomic architecture of glycemic traits. Nature Genetics. PMID 34059833 DOI: 10.1038/s41588-021-00852-9 |
0.371 |
|
| 2020 |
Surendran P, Feofanova EV, Lahrouchi N, Ntalla I, Karthikeyan S, Cook J, Chen L, Mifsud B, Yao C, Kraja AT, Cartwright JH, Hellwege JN, Giri A, Tragante V, Thorleifsson G, ... ... Mohlke KL, et al. Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals. Nature Genetics. PMID 33230300 DOI: 10.1038/s41588-020-00713-x |
0.399 |
|
| 2020 |
Sigmon JS, Blanchard MW, Baric RS, Bell TA, Brennan J, Brockmann GA, Burks AW, Calabrese JM, Caron KM, Cheney RE, Ciavatta D, Conlon F, Darr DB, Faber J, Franklin C, ... ... Mohlke KL, et al. Content and Performance of the MiniMUGA Genotyping Array, a New Tool To Improve Rigor and Reproducibility in Mouse Research. Genetics. PMID 33067325 DOI: 10.1534/genetics.120.303596 |
0.311 |
|
| 2020 |
Viñuela A, Varshney A, van de Bunt M, Prasad RB, Asplund O, Bennett A, Boehnke M, Brown AA, Erdos MR, Fadista J, Hansson O, Hatem G, Howald C, Iyengar AK, Johnson P, ... ... Mohlke KL, et al. Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D. Nature Communications. 11: 4912. PMID 32999275 DOI: 10.1038/s41467-020-18581-8 |
0.363 |
|
| 2020 |
Miao Z, Alvarez M, Ko A, Bhagat Y, Rahmani E, Jew B, Heinonen S, Muñoz-Hernandez LL, Herrera-Hernandez M, Aguilar-Salinas C, Tusie-Luna T, Mohlke KL, Laakso M, Pietiläinen KH, Halperin E, et al. The causal effect of obesity on prediabetes and insulin resistance reveals the important role of adipose tissue in insulin resistance. Plos Genetics. 16: e1009018. PMID 32925908 DOI: 10.1371/Journal.Pgen.1009018 |
0.318 |
|
| 2020 |
Yaghootkar H, Zhang Y, Spracklen CN, Karaderi T, Huang LO, Bradfield J, Schurmann C, Fine RS, Preuss MH, Kutalik Z, Wittemans LB, Lu Y, Metz S, Willems SM, Li-Gao R, ... ... Mohlke KL, et al. Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. Diabetes. PMID 32917775 DOI: 10.2337/Db20-0070 |
0.483 |
|
| 2020 |
Spracklen CN, Iyengar AK, Vadlamudi S, Raulerson CK, Jackson AU, Brotman SM, Wu Y, Cannon ME, Davis JP, Crain AT, Currin KW, Perrin HJ, Narisu N, Stringham HM, Fuchsberger C, ... ... Mohlke KL, et al. Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences. Plos Genetics. 16: e1009019. PMID 32915782 DOI: 10.1371/Journal.Pgen.1009019 |
0.488 |
|
| 2020 |
Vuckovic D, Bao EL, Akbari P, Lareau CA, Mousas A, Jiang T, Chen MH, Raffield LM, Tardaguila M, Huffman JE, Ritchie SC, Megy K, Ponstingl H, Penkett CJ, Albers PK, ... ... Mohlke KL, et al. The Polygenic and Monogenic Basis of Blood Traits and Diseases. Cell. 182: 1214-1231.e11. PMID 32888494 DOI: 10.1016/J.Cell.2020.08.008 |
0.416 |
|
| 2020 |
Chen MH, Raffield LM, Mousas A, Sakaue S, Huffman JE, Moscati A, Trivedi B, Jiang T, Akbari P, Vuckovic D, Bao EL, Zhong X, Manansala R, Laplante V, Chen M, ... ... Mohlke KL, et al. Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Cell. 182: 1198-1213.e14. PMID 32888493 DOI: 10.1016/J.Cell.2020.06.045 |
0.45 |
|
| 2020 |
El-Sayed Moustafa JS, Jackson AU, Brotman SM, Guan L, Villicaňa S, Roberts AL, Zito A, Bonnycastle L, Erdos MR, Narisu N, Stringham HM, Welch R, Yan T, Lakka T, Parker S, ... ... Mohlke KL, et al. ACE2 expression in adipose tissue is associated with COVID-19 cardio-metabolic risk factors and cell type composition. Medrxiv : the Preprint Server For Health Sciences. PMID 32817962 DOI: 10.1101/2020.08.11.20171108 |
0.317 |
|
| 2020 |
Frank DN, Giese APJ, Hafren L, Bootpetch TC, Yarza TKL, Steritz MJ, Pedro M, Labra PJ, Daly KA, Tantoco MLC, Szeremeta W, Reyes-Quintos MRT, Ahankoob N, Llanes EGDV, Pine HS, ... ... Mohlke KL, et al. Otitis media susceptibility and shifts in the head and neck microbiome due to variants. Journal of Medical Genetics. PMID 32709676 DOI: 10.1136/Jmedgenet-2020-106844 |
0.386 |
|
| 2020 |
Spracklen CN, Horikoshi M, Kim YJ, Lin K, Bragg F, Moon S, Suzuki K, Tam CHT, Tabara Y, Kwak SH, Takeuchi F, Long J, Lim VJY, Chai JF, Chen CH, ... ... Mohlke KL, et al. Identification of type 2 diabetes loci in 433,540 East Asian individuals. Nature. PMID 32499647 DOI: 10.1038/S41586-020-2263-3 |
0.537 |
|
| 2020 |
Zheng Y, Huang T, Wang T, Mei Z, Sun Z, Zhang T, Ellervik C, Chai JF, Sim X, van Dam RM, Tai ES, Koh WP, Dorajoo R, Saw SM, Sabanayagam C, ... ... Mohlke KL, et al. Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood. European Journal of Epidemiology. PMID 32383070 DOI: 10.1007/S10654-020-00638-Z |
0.405 |
|
| 2020 |
Zhong W, Dong L, Poston TB, Darville T, Spracklen CN, Wu D, Mohlke KL, Li Y, Li Q, Zheng X. Inferring Regulatory Networks From Mixed Observational Data Using Directed Acyclic Graphs. Frontiers in Genetics. 11: 8. PMID 32127796 DOI: 10.3389/Fgene.2020.00008 |
0.301 |
|
| 2019 |
Raffield LM, Iyengar AK, Wang B, Gaynor SM, Spracklen CN, Zhong X, Kowalski MH, Salimi S, Polfus LM, Benjamin EJ, Bis JC, Bowler R, Cade BE, Choi WJ, Comellas AP, ... ... Mohlke KL, et al. Allelic Heterogeneity at the CRP Locus Identified by Whole-Genome Sequencing in Multi-ancestry Cohorts. American Journal of Human Genetics. PMID 31883642 DOI: 10.1016/J.Ajhg.2019.12.002 |
0.523 |
|
| 2019 |
Etheridge AS, Gallins PJ, Jima D, Broadaway KA, Ratain MJ, Schuetz E, Schadt E, Schroder A, Molony C, Zhou Y, Mohlke KL, Wright FA, Innocenti F. A new liver eQTL map from 1,183 individuals provides evidence for novel eQTLs of drug response, metabolic and sex-biased phenotypes. Clinical Pharmacology and Therapeutics. PMID 31868224 DOI: 10.1002/Cpt.1751 |
0.382 |
|
| 2019 |
Wu Y, Broadaway KA, Raulerson CK, Scott LJ, Pan C, Ko A, He A, Tilford C, Fuchsberger C, Locke AE, Stringham HM, Jackson AU, Narisu N, Kuusisto J, Pajukanta P, ... ... Mohlke KL, et al. Colocalization of GWAS and eQTL signals at loci with multiple signals identifies additional candidate genes for body fat distribution. Human Molecular Genetics. PMID 31691812 DOI: 10.1093/Hmg/Ddz263 |
0.398 |
|
| 2019 |
Clark DW, Okada Y, Moore KHS, Mason D, Pirastu N, Gandin I, Mattsson H, Barnes CLK, Lin K, Zhao JH, Deelen P, Rohde R, Schurmann C, Guo X, Giulianini F, ... ... Mohlke KL, et al. Associations of autozygosity with a broad range of human phenotypes. Nature Communications. 10: 4957. PMID 31673082 DOI: 10.1038/S41467-019-12283-6 |
0.382 |
|
| 2019 |
Tin A, Marten J, Halperin Kuhns VL, Li Y, Wuttke M, Kirsten H, Sieber KB, Qiu C, Gorski M, Yu Z, Giri A, Sveinbjornsson G, Li M, Chu AY, Hoppmann A, ... ... Mohlke KL, et al. Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels. Nature Genetics. PMID 31578528 DOI: 10.1038/S41588-019-0504-X |
0.446 |
|
| 2019 |
Raulerson CK, Ko A, Kidd JC, Currin KW, Brotman SM, Cannon ME, Wu Y, Spracklen CN, Jackson AU, Stringham HM, Welch RP, Fuchsberger C, Locke AE, Narisu N, Lusis AJ, ... ... Mohlke KL, et al. Adipose Tissue Gene Expression Associations Reveal Hundreds of Candidate Genes for Cardiometabolic Traits. American Journal of Human Genetics. PMID 31564431 DOI: 10.1016/J.Ajhg.2019.09.001 |
0.485 |
|
| 2019 |
Garske KM, Pan DZ, Miao Z, Bhagat YV, Comenho C, Robles CR, Benhammou JN, Alvarez M, Ko A, Ye CJ, Pisegna JR, Mohlke KL, Sinsheimer JS, Laakso M, Pajukanta P. Reverse gene-environment interaction approach to identify variants influencing body-mass index in humans. Nature Metabolism. 1: 630-642. PMID 31538139 DOI: 10.1038/s42255-019-0071-6 |
0.313 |
|
| 2019 |
Spracklen CN, Karaderi T, Yaghootkar H, Schurmann C, Fine RS, Kutalik Z, Preuss MH, Lu Y, Wittemans LBL, Adair LS, Allison M, Amin N, Auer PL, Bartz TM, Blüher M, ... ... Mohlke KL, et al. Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology. American Journal of Human Genetics. 105: 670-671. PMID 31491410 DOI: 10.1016/J.Ajhg.2019.08.001 |
0.398 |
|
| 2019 |
Evangelou E, Gao H, Chu C, Ntritsos G, Blakeley P, Butts AR, Pazoki R, Suzuki H, Koskeridis F, Yiorkas AM, Karaman I, Elliott J, Luo Q, Aeschbacher S, Bartz TM, ... ... Mohlke KL, et al. New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders. Nature Human Behaviour. PMID 31358974 DOI: 10.1038/S41562-019-0653-Z |
0.335 |
|
| 2019 |
Cannon ME, Currin KW, Young KL, Perrin HJ, Vadlamudi S, Safi A, Song L, Wu Y, Wabitsch M, Laakso M, Crawford GE, Mohlke KL. Open Chromatin Profiling in Adipose Tissue Marks Genomic Regions with Functional Roles in Cardiometabolic Traits. G3 (Bethesda, Md.). PMID 31186305 DOI: 10.1534/G3.119.400294 |
0.407 |
|
| 2019 |
Spracklen CN, Karaderi T, Yaghootkar H, Schurmann C, Fine RS, Kutalik Z, Preuss MH, Lu Y, Wittemans LBL, Adair LS, Allison M, Amin N, Auer PL, Bartz TM, Blüher M, ... ... Mohlke KL, et al. Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology. American Journal of Human Genetics. PMID 31178129 DOI: 10.1016/J.Ajhg.2019.05.002 |
0.525 |
|
| 2019 |
Flannick J, Mercader JM, Fuchsberger C, Udler MS, Mahajan A, Wessel J, Teslovich TM, Caulkins L, Koesterer R, Barajas-Olmos F, Blackwell TW, Boerwinkle E, Brody JA, Centeno-Cruz F, Chen L, ... ... Mohlke KL, et al. Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls. Nature. PMID 31118516 DOI: 10.1038/s41586-019-1231-2 |
0.376 |
|
| 2019 |
Zhong W, Spracklen CN, Mohlke KL, Zheng X, Fine J, Li Y. Multi-SNP mediation intersection-union test. Bioinformatics (Oxford, England). PMID 31099385 DOI: 10.1093/Bioinformatics/Btz285 |
0.327 |
|
| 2019 |
Jia Q, Han Y, Huang P, Woodward NC, Gukasyan J, Kettunen J, Ala-Korpela M, Anufrieva O, Wang Q, Perola M, Raitakari O, Lehtimäki T, Viikari J, Järvelin MR, Boehnke M, ... ... Mohlke KL, et al. Genetic Determinants of Circulating Glycine Levels and Risk of Coronary Artery Disease. Journal of the American Heart Association. 8: e011922. PMID 31070104 DOI: 10.1161/Jaha.119.011922 |
0.388 |
|
| 2019 |
Warrington NM, Beaumont RN, Horikoshi M, Day FR, Helgeland Ø, Laurin C, Bacelis J, Peng S, Hao K, Feenstra B, Wood AR, Mahajan A, Tyrrell J, Robertson NR, Rayner NW, ... ... Mohlke KL, et al. Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors. Nature Genetics. PMID 31043758 DOI: 10.1038/S41588-019-0403-1 |
0.618 |
|
| 2019 |
Bentley AR, Sung YJ, Brown MR, Winkler TW, Kraja AT, Ntalla I, Schwander K, Chasman DI, Lim E, Deng X, Guo X, Liu J, Lu Y, Cheng CY, Sim X, ... ... Mohlke KL, et al. Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. Nature Genetics. 51: 636-648. PMID 30926973 DOI: 10.1038/S41588-019-0378-Y |
0.403 |
|
| 2019 |
Truong BT, Yarza TKL, Bootpetch Roberts T, Roberts S, Xu J, Steritz MJ, Tobias-Grasso CAM, Azamian M, Lalani SR, Mohlke KL, Lee NR, Cutiongco-de la Paz EM, Reyes-Quintos MRT, Santos-Cortez RLP, Chiong CM. Exome sequencing reveals novel variants and unique allelic spectrum for hearing impairment in Filipino cochlear implantees. Clinical Genetics. PMID 30828794 DOI: 10.1111/Cge.13515 |
0.34 |
|
| 2019 |
Justice AE, Karaderi T, Highland HM, Young KL, Graff M, Lu Y, Turcot V, Auer PL, Fine RS, Guo X, Schurmann C, Lempradl A, Marouli E, Mahajan A, Winkler TW, ... ... Mohlke KL, et al. Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. Nature Genetics. PMID 30778226 DOI: 10.1038/S41588-018-0334-2 |
0.422 |
|
| 2019 |
de Vries PS, Brown MR, Bentley AR, Sung YJ, Winkler TW, Ntalla I, Schwander K, Kraja AT, Guo X, Franceschini N, Cheng CY, Sim X, Vojinovic D, Huffman JE, Musani SK, ... ... Mohlke KL, et al. Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. American Journal of Epidemiology. PMID 30698716 DOI: 10.1093/Aje/Kwz005 |
0.429 |
|
| 2019 |
Kilpeläinen TO, Bentley AR, Noordam R, Sung YJ, Schwander K, Winkler TW, Jakupović H, Chasman DI, Manning A, Ntalla I, Aschard H, Brown MR, de Las Fuentes L, Franceschini N, Guo X, ... ... Mohlke KL, et al. Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity. Nature Communications. 10: 376. PMID 30670697 DOI: 10.1038/S41467-018-08008-W |
0.399 |
|
| 2019 |
Liu M, Jiang Y, Wedow R, Li Y, Brazel DM, Chen F, Datta G, Davila-Velderrain J, McGuire D, Tian C, Zhan X, Choquet H, Docherty AR, ... ... Mohlke KL, et al. Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use. Nature Genetics. PMID 30643251 DOI: 10.1038/S41588-018-0307-5 |
0.337 |
|
| 2018 |
Takeuchi F, Akiyama M, Matoba N, Katsuya T, Nakatochi M, Tabara Y, Narita A, Saw WY, Moon S, Spracklen CN, Chai JF, Kim YJ, Zhang L, Wang C, Li H, ... ... Mohlke KL, et al. Interethnic analyses of blood pressure loci in populations of East Asian and European descent. Nature Communications. 9: 5052. PMID 30487518 DOI: 10.1038/S41467-018-07345-0 |
0.508 |
|
| 2018 |
Davis JP, Vadlamudi S, Roman TS, Zeynalzadeh M, Iyengar AK, Mohlke KL. Enhancer deletion and allelic effects define a regulatory molecular mechanism at the VLDLR cholesterol GWAS locus. Human Molecular Genetics. PMID 30445632 DOI: 10.1093/Hmg/Ddy385 |
0.478 |
|
| 2018 |
Ligthart S, Vaez A, Võsa U, Stathopoulou MG, de Vries PS, Prins BP, Van der Most PJ, Tanaka T, Naderi E, Rose LM, Wu Y, Karlsson R, Barbalic M, Lin H, Pool R, ... ... Mohlke KL, et al. Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders. American Journal of Human Genetics. 103: 691-706. PMID 30388399 DOI: 10.1016/J.Ajhg.2018.09.009 |
0.342 |
|
| 2018 |
Cannon ME, Mohlke KL. Deciphering the Emerging Complexities of Molecular Mechanisms at GWAS Loci. American Journal of Human Genetics. 103: 637-653. PMID 30388398 DOI: 10.1016/j.ajhg.2018.10.001 |
0.405 |
|
| 2018 |
Mahajan A, Taliun D, Thurner M, Robertson NR, Torres JM, Rayner NW, Payne AJ, Steinthorsdottir V, Scott RA, Grarup N, Cook JP, Schmidt EM, Wuttke M, Sarnowski C, Mägi R, ... ... Mohlke KL, et al. Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps. Nature Genetics. PMID 30297969 DOI: 10.1038/S41588-018-0241-6 |
0.392 |
|
| 2018 |
Pan DZ, Garske KM, Alvarez M, Bhagat YV, Boocock J, Nikkola E, Miao Z, Raulerson CK, Cantor RM, Civelek M, Glastonbury CA, Small KS, Boehnke M, Lusis AJ, Sinsheimer JS, ... Mohlke KL, et al. Author Correction: Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS. Nature Communications. 9: 3472. PMID 30135520 DOI: 10.1038/S41467-018-05849-3 |
0.378 |
|
| 2018 |
Feitosa MF, Kraja AT, Chasman DI, Sung YJ, Winkler TW, Ntalla I, Guo X, Franceschini N, Cheng CY, Sim X, Vojinovic D, Marten J, Musani SK, Li C, Bentley AR, ... ... Mohlke KL, et al. Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. Plos One. 13: e0198166. PMID 29912962 DOI: 10.1371/Journal.Pone.0198166 |
0.401 |
|
| 2018 |
Orozco LD, Farrell C, Hale C, Rubbi L, Rinaldi A, Civelek M, Pan C, Lam L, Montoya D, Edillor C, Seldin M, Boehnke M, Mohlke KL, Jacobsen S, Kuusisto J, et al. Epigenome-wide association in adipose tissue from the METSIM cohort. Human Molecular Genetics. PMID 29893869 DOI: 10.1093/Hmg/Ddy205 |
0.339 |
|
| 2018 |
Pan DZ, Garske KM, Alvarez M, Bhagat YV, Boocock J, Nikkola E, Miao Z, Raulerson CK, Cantor RM, Civelek M, Glastonbury CA, Small KS, Boehnke M, Lusis AJ, Sinsheimer JS, ... Mohlke KL, et al. Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS. Nature Communications. 9: 1512. PMID 29666371 DOI: 10.1038/S41467-018-03554-9 |
0.427 |
|
| 2018 |
Mahajan A, Wessel J, Willems SM, Zhao W, Robertson NR, Chu AY, Gan W, Kitajima H, Taliun D, Rayner NW, Guo X, Lu Y, Li M, Jensen RA, Hu Y, ... ... Mohlke KL, et al. Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes. Nature Genetics. 50: 559-571. PMID 29632382 DOI: 10.1038/S41588-018-0084-1 |
0.462 |
|
| 2018 |
Kycia I, Wolford BN, Huyghe JR, Fuchsberger C, Vadlamudi S, Kursawe R, Welch RP, Albanus RD, Uyar A, Khetan S, Lawlor N, Bolisetty M, Mathur A, Kuusisto J, Laakso M, ... ... Mohlke KL, et al. A Common Type 2 Diabetes Risk Variant Potentiates Activity of an Evolutionarily Conserved Islet Stretch Enhancer and Increases C2CD4A and C2CD4B Expression. American Journal of Human Genetics. 102: 620-635. PMID 29625024 DOI: 10.1016/J.Ajhg.2018.02.020 |
0.526 |
|
| 2018 |
Spracklen CN, Shi J, Vadlamudi S, Wu Y, Zou M, Raulerson CK, Davis JP, Zeynalzadeh M, Jackson K, Yuan W, Wang H, Shou W, Wang Y, Luo J, Lange LA, ... ... Mohlke KL, et al. Identification and functional analysis of glycemic trait loci in the China Health and Nutrition Survey. Plos Genetics. 14: e1007275. PMID 29621232 DOI: 10.1371/Journal.Pgen.1007275 |
0.503 |
|
| 2018 |
Orozco LD, Farrell C, Hale C, Rbi L, Rinaldi A, Civelek M, Pan C, Lam L, Montoya D, Edillor C, Seldin M, Mohlke KL, Jacobsen S, Kuusisto J, Laakso M, et al. Epigenome-wide association in adipose tissue from the METSIM cohort. Human Molecular Genetics. PMID 29566149 DOI: 10.1093/Hmg/Ddy093 |
0.411 |
|
| 2018 |
Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T, Giri A, Graff M, Guo X, Hendricks AE, Karaderi T, Lempradl A, Locke AE, ... ... Mohlke KL, et al. Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. Nature Genetics. PMID 29549329 DOI: 10.1038/S41588-018-0050-Y |
0.319 |
|
| 2018 |
Teslovich TM, Kim DS, Yin X, Stancáková A, Jackson AU, Wielscher M, Naj A, Perry JRB, Huyghe JR, Stringham HM, Davis JP, Raulerson CK, Welch RP, Fuchsberger C, Locke AE, ... ... Mohlke KL, et al. Identification of seven novel loci associated with amino acid levels using single variant and gene-based tests in 8,545 Finnish men from the METSIM study. Human Molecular Genetics. PMID 29481666 DOI: 10.1093/Hmg/Ddy067 |
0.464 |
|
| 2018 |
Roman TS, Mohlke KL. Functional genomics and assays of regulatory activity detect mechanisms at loci for lipid traits and coronary artery disease. Current Opinion in Genetics & Development. 50: 52-59. PMID 29471259 DOI: 10.1016/J.Gde.2018.02.004 |
0.421 |
|
| 2018 |
Flannick J, Fuchsberger C, Mahajan A, Teslovich TM, Agarwala V, Gaulton KJ, Caulkins L, Koesterer R, Ma C, Moutsianas L, McCarthy DJ, Rivas MA, Perry JRB, Sim X, Blackwell TW, ... ... Mohlke KL, et al. Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Scientific Data. 5: 180002. PMID 29360107 DOI: 10.1038/sdata.2018.2 |
0.597 |
|
| 2018 |
Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T, Giri A, Graff M, Guo X, Hendricks AE, Karaderi T, Lempradl A, Locke AE, ... ... Mohlke KL, et al. Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. Nature Genetics. 50: 26-41. PMID 29273807 DOI: 10.1038/S41588-017-0011-X |
0.488 |
|
| 2017 |
Jun G, Manning A, Almeida M, Zawistowski M, Wood AR, Teslovich TM, Fuchsberger C, Feng S, Cingolani P, Gaulton KJ, Dyer T, Blackwell TW, Chen H, Chines PS, Choi S, ... ... Mohlke KL, et al. Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees. Proceedings of the National Academy of Sciences of the United States of America. PMID 29279374 DOI: 10.1073/Pnas.1705859115 |
0.722 |
|
| 2017 |
Jason F, Fuchsberger C, Mahajan A, Teslovich TM, Agarwala V, Gaulton KJ, Caulkins L, Koesterer R, Ma C, Moutsianas L, McCarthy DJ, Rivas MA, Perry JRB, Sim X, Blackwell TW, ... ... Mohlke KL, et al. Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Scientific Data. 4: 170179. PMID 29257133 DOI: 10.1038/Sdata.2017.179 |
0.686 |
|
| 2017 |
Latva-Rasku A, Honka MJ, Stančáková A, Koistinen HA, Kuusisto J, Guan L, Manning AK, Stringham H, Gloyn AL, Lindgren CM, Collins FS, Mohlke KL, Scott LJ, Karjalainen T, et al. A Partial Loss-of-Function Variant in AKT2 is Associated with Reduced Insulin-Mediated Glucose Uptake in Multiple Insulin Sensitive Tissues: a Genotype-Based Callback Positron Emission Tomography Study. Diabetes. PMID 29141982 DOI: 10.2337/Db17-1142 |
0.37 |
|
| 2017 |
Davis JP, Huyghe JR, Locke AE, Jackson AU, Sim X, Stringham HM, Teslovich TM, Welch RP, Fuchsberger C, Narisu N, Chines PS, Kangas AJ, Soininen P, Ala-Korpela M, Kuusisto J, ... ... Mohlke KL, et al. Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study. Plos Genetics. 13: e1007079. PMID 29084231 DOI: 10.1371/Journal.Pgen.1007079 |
0.543 |
|
| 2017 |
Lu X, Peloso GM, Liu DJ, Wu Y, Zhang H, Zhou W, Li J, Tang CS, Dorajoo R, Li H, Long J, Guo X, Xu M, Spracklen CN, Chen Y, ... ... Mohlke KL, et al. Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants that contribute to lipid levels and coronary artery disease. Nature Genetics. PMID 29083407 DOI: 10.1038/Ng.3978 |
0.529 |
|
| 2017 |
Kraja AT, Cook JP, Warren HR, Surendran P, Liu C, Evangelou E, Manning AK, Grarup N, Drenos F, Sim X, Smith AV, Amin N, Blakemore AIF, Bork-Jensen J, Brandslund I, ... ... Mohlke KL, et al. New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals. Circulation. Cardiovascular Genetics. 10. PMID 29030403 DOI: 10.1161/Circgenetics.117.001778 |
0.482 |
|
| 2017 |
Graff M, Scott RA, Justice AE, Young KL, Feitosa MF, Barata L, Winkler TW, Chu AY, Mahajan A, Hadley D, Xue L, Workalemahu T, Heard-Costa NL, den Hoed M, Ahluwalia TS, ... ... Mohlke KL, et al. Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. Plos Genetics. 13: e1006972. PMID 28832619 DOI: 10.1371/Journal.Pgen.1006972 |
0.326 |
|
| 2017 |
Cannon ME, Duan Q, Wu Y, Zeynalzadeh M, Xu Z, Kangas AJ, Soininen P, Ala-Korpela M, Civelek M, Lusis AJ, Kuusisto J, Collins FS, Boehnke M, Tang H, Laakso M, ... ... Mohlke K, et al. Trans-ancestry Fine Mapping and Molecular Assays Identify Regulatory Variants at the ANGPTL8 HDL-C GWAS Locus. G3 (Bethesda, Md.). PMID 28754724 DOI: 10.1534/G3.117.300088 |
0.512 |
|
| 2017 |
Roman TS, Cannon ME, Vadlamudi S, Buchkovich ML, Wolford BN, Welch RP, Morken MA, Kwon GJ, Varshney A, Kursawe R, Wu Y, Jackson AU, Erdos MR, Kuusisto J, ... ... Mohlke KL, et al. A Type 2 Diabetes-Associated Functional Regulatory Variant in a Pancreatic Islet Enhancer at the Adcy5 Locus. Diabetes. PMID 28684635 DOI: 10.2337/Db17-0464 |
0.453 |
|
| 2017 |
Martin JS, Xu Z, Reiner AP, Mohlke KL, Sullivan P, Ren B, Hu M, Li Y. HUGIn: Hi-C Unifying Genomic Interrogator. Bioinformatics (Oxford, England). PMID 28582503 DOI: 10.1093/Bioinformatics/Btx359 |
0.305 |
|
| 2017 |
Stančáková A, Kuulasmaa T, Kuusisto J, Mohlke KL, Collins FS, Boehnke M, Laakso M. Genetic risk scores in the prediction of plasma glucose, impaired insulin secretion, insulin resistance and incident type 2 diabetes in the METSIM study. Diabetologia. PMID 28573393 DOI: 10.1007/S00125-017-4313-4 |
0.378 |
|
| 2017 |
Scott RA, Scott LJ, Mägi R, Marullo L, Gaulton KJ, Kaakinen M, Pervjakova N, Pers TH, Johnson AD, Eicher JD, Jackson AU, Ferreira T, Lee Y, Ma C, Steinthorsdottir V, ... ... Mohlke KL, et al. An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans. Diabetes. PMID 28566273 DOI: 10.2337/Db16-1253 |
0.754 |
|
| 2017 |
Graff M, Scott RA, Justice AE, Young KL, Feitosa MF, Barata L, Winkler TW, Chu AY, Mahajan A, Hadley D, Xue L, Workalemahu T, Heard-Costa NL, den Hoed M, Ahluwalia TS, ... ... Mohlke KL, et al. Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. Plos Genetics. 13: e1006528. PMID 28448500 DOI: 10.1371/Journal.Pgen.1006528 |
0.417 |
|
| 2017 |
Justice AE, Winkler TW, Feitosa MF, Graff M, Fisher VA, Young K, Barata L, Deng X, Czajkowski J, Hadley D, Ngwa JS, Ahluwalia TS, Chu AY, Heard-Costa NL, Lim E, ... ... Mohlke KL, et al. Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Nature Communications. 8: 14977. PMID 28443625 DOI: 10.1038/Ncomms14977 |
0.451 |
|
| 2017 |
Manning A, Highland HM, Gasser J, Sim X, Tukiainen T, Fontanillas P, Grarup N, Rivas MA, Mahajan A, Locke AE, Cingolani P, Pers TH, Viñuela A, Brown AA, Wu Y, ... ... Mohlke KL, et al. A Low-Frequency Inactivating Akt2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk. Diabetes. PMID 28341696 DOI: 10.2337/Db16-1329 |
0.704 |
|
| 2017 |
Spracklen CN, Chen P, Kim YJ, Wang X, Cai H, Li S, Long J, Wu Y, Wang YX, Takeuchi F, Wu JY, Jung KJ, Hu C, Akiyama K, Zhang Y, ... ... Mohlke KL, et al. Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels. Human Molecular Genetics. PMID 28334899 DOI: 10.1093/Hmg/Ddx062 |
0.502 |
|
| 2017 |
Civelek M, Wu Y, Pan C, Raulerson CK, Ko A, He A, Tilford C, Saleem NK, Stančáková A, Scott LJ, Fuchsberger C, Stringham HM, Jackson AU, Narisu N, Chines PS, ... ... Mohlke KL, et al. Genetic Regulation of Adipose Gene Expression and Cardio-Metabolic Traits. American Journal of Human Genetics. 100: 428-443. PMID 28257690 DOI: 10.1016/J.Ajhg.2017.01.027 |
0.455 |
|
| 2017 |
Varshney A, Scott LJ, Welch RP, Erdos MR, Chines PS, Narisu N, Albanus RD, Orchard P, Wolford BN, Kursawe R, Vadlamudi S, Cannon ME, Didion JP, Hensley J, Kirilusha A, ... ... Mohlke KL, et al. Genetic regulatory signatures underlying islet gene expression and type 2 diabetes. Proceedings of the National Academy of Sciences of the United States of America. PMID 28193859 DOI: 10.1073/Pnas.1621192114 |
0.496 |
|
| 2017 |
Marouli E, Graff M, Medina-Gomez C, Lo KS, Wood AR, Kjaer TR, Fine RS, Lu Y, Schurmann C, Highland HM, Rüeger S, Thorleifsson G, Justice AE, Lamparter D, Stirrups KE, ... ... Mohlke KL, et al. Rare and low-frequency coding variants alter human adult height. Nature. PMID 28146470 DOI: 10.1038/Nature21039 |
0.503 |
|
| 2017 |
Laakso M, Kuusisto J, Stancakova A, Kuulasmaa T, Pajukanta P, Lusis AJ, Collins FS, Mohlke K, Boehnke M. METabolic Syndrome In Men (METSIM) Study: a resource for studies of metabolic and cardiovascular diseases. Journal of Lipid Research. PMID 28119442 DOI: 10.1194/Jlr.O072629 |
0.468 |
|
| 2016 |
Graff M, North KE, Richardson AS, Young KL, Mazul AL, Highland HM, Mohlke KL, Lange LA, Lange EM, Harris KM, Gordon-Larsen P. BMI loci and longitudinal BMI from adolescence to young adulthood in an ethnically diverse cohort. International Journal of Obesity (2005). PMID 28025578 DOI: 10.1038/Ijo.2016.233 |
0.349 |
|
| 2016 |
Li M, Li Y, Weeks O, Mijatovic V, Teumer A, Huffman JE, Tromp G, Fuchsberger C, Gorski M, Lyytikäinen LP, Nutile T, Sedaghat S, Sorice R, Tin A, Yang Q, ... ... Mohlke KL, et al. SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function. Journal of the American Society of Nephrology : Jasn. PMID 27920155 DOI: 10.1681/Asn.2016020131 |
0.485 |
|
| 2016 |
Ried JS, Jeff M J, Chu AY, Bragg-Gresham JL, van Dongen J, Huffman JE, Ahluwalia TS, Cadby G, Eklund N, Eriksson J, Esko T, Feitosa MF, Goel A, Gorski M, Hayward C, ... ... Mohlke KL, et al. A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape. Nature Communications. 7: 13357. PMID 27876822 DOI: 10.1038/Ncomms13357 |
0.46 |
|
| 2016 |
Graff M, Richardson AS, Young KL, Mazul AL, Highland H, North KE, Mohlke KL, Lange LA, Lange EM, Harris KM, Gordon-Larsen P. The interaction between physical activity and obesity gene variants in association with BMI: Does the obesogenic environment matter? Health & Place. 42: 159-165. PMID 27771443 DOI: 10.1016/J.Healthplace.2016.09.003 |
0.384 |
|
| 2016 |
Horikoshi M, Beaumont RN, Day FR, Warrington NM, Kooijman MN, Fernandez-Tajes J, Feenstra B, van Zuydam NR, Gaulton KJ, Grarup N, Bradfield JP, Strachan DP, Li-Gao R, Ahluwalia TS, Kreiner E, ... ... Mohlke KL, et al. Genome-wide associations for birth weight and correlations with adult disease. Nature. PMID 27680694 DOI: 10.1038/Nature19806 |
0.733 |
|
| 2016 |
Ehret GB, Ferreira T, Chasman DI, Jackson AU, Schmidt EM, Johnson T, Thorleifsson G, Luan J, Donnelly LA, Kanoni S, Petersen AK, Pihur V, Strawbridge RJ, Shungin D, Hughes MF, ... ... Mohlke KL, et al. The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Nature Genetics. PMID 27618452 DOI: 10.1038/Ng.3667 |
0.389 |
|
| 2016 |
Surendran P, Drenos F, Young R, Warren H, Cook JP, Manning AK, Grarup N, Sim X, Barnes DR, Witkowska K, Staley JR, Tragante V, Tukiainen T, Yaghootkar H, Masca N, ... ... Mohlke KL, et al. Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension. Nature Genetics. PMID 27618447 DOI: 10.1038/Ng.3654 |
0.419 |
|
| 2016 |
McCarthy S, Das S, Kretzschmar W, Delaneau O, Wood AR, Teumer A, Kang HM, Fuchsberger C, Danecek P, Sharp K, Luo Y, Sidore C, Kwong A, Timpson N, Koskinen S, ... ... Mohlke KL, et al. A reference panel of 64,976 haplotypes for genotype imputation. Nature Genetics. PMID 27548312 DOI: 10.1038/Ng.3643 |
0.481 |
|
| 2016 |
Lange LA, Graff M, Lange EM, Young KL, Richardson AS, Mohlke KL, North KE, Harris KM, Gordon-Larsen P. Evidence for Association between SH2B1 Gene Variants and Glycated Hemoglobin in Nondiabetic European American Young Adults: The Add Health Study. Annals of Human Genetics. 80: 294-305. PMID 27530450 DOI: 10.1111/Ahg.12165 |
0.477 |
|
| 2016 |
Walford GA, Gustafsson S, Rybin D, Stančáková A, Chen H, Liu CT, Hong J, Jensen RA, Rice K, Morris AP, Mägi R, Tönjes A, Prokopenko I, Kleber ME, Delgado G, ... ... Mohlke KL, et al. Genome-wide association study of the modified Stumvoll Insulin Sensitivity Index identifies BCL2 and FAM19A2 as novel insulin sensitivity loci. Diabetes. PMID 27416945 DOI: 10.2337/Db16-0199 |
0.475 |
|
| 2016 |
Fuchsberger C, Flannick J, Teslovich TM, Mahajan A, Agarwala V, Gaulton KJ, Ma C, Fontanillas P, Moutsianas L, McCarthy DJ, Rivas MA, Perry JR, Sim X, Blackwell TW, Robertson NR, ... ... Mohlke KL, et al. The genetic architecture of type 2 diabetes. Nature. PMID 27398621 DOI: 10.1038/Nature18642 |
0.715 |
|
| 2016 |
Scott RA, Freitag DF, Li L, Chu AY, Surendran P, Young R, Grarup N, Stancáková A, Chen Y, Varga TV, Yaghootkar H, Luan J, Zhao JH, Willems SM, Wessel J, ... ... Mohlke KL, et al. A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease. Science Translational Medicine. 8: 341ra76. PMID 27252175 DOI: 10.1126/scitranslmed.aad3744 |
0.34 |
|
| 2016 |
Rodríguez A, Gonzalez L, Ko A, Alvarez M, Miao Z, Bhagat Y, Nikkola E, Cruz-Bautista I, Arellano-Campos O, Muñoz-Hernández LL, Ordóñez-Sánchez ML, Rodriguez-Guillen R, Mohlke KL, Laakso M, Tusie-Luna T, et al. Molecular Characterization of the Lipid Genome-Wide Association Study Signal on Chromosome 18q11.2 Implicates HNF4A-Mediated Regulation of the TMEM241 Gene. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 27199446 DOI: 10.1161/Atvbaha.116.307182 |
0.46 |
|
| 2016 |
Horikoshi M, Pasquali L, Wiltshire S, Huyghe JR, Mahajan A, Asimit JL, Ferreira T, Locke AE, Robertson NR, Wang X, Sim X, Fujita H, Hara K, Young R, Zhang W, ... ... Mohlke KL, et al. Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms. Human Molecular Genetics. PMID 26911676 DOI: 10.1093/Hmg/Ddw048 |
0.494 |
|
| 2016 |
Lu Y, Day FR, Gustafsson S, Buchkovich ML, Na J, Bataille V, Cousminer DL, Dastani Z, Drong AW, Esko T, Evans DM, Falchi M, Feitosa MF, Ferreira T, Hedman ÅK, ... ... Mohlke KL, et al. New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk. Nature Communications. 7: 10495. PMID 26833246 DOI: 10.1038/Ncomms10495 |
0.515 |
|
| 2016 |
Schick UM, Jain D, Hodonsky CJ, Morrison JV, Davis JP, Brown L, Sofer T, Conomos MP, Schurmann C, McHugh CP, Nelson SC, Vadlamudi S, Stilp A, Plantinga A, Baier L, ... ... Mohlke KL, et al. Genome-wide Association Study of Platelet Count Identifies Ancestry-Specific Loci in Hispanic/Latino Americans. American Journal of Human Genetics. PMID 26805783 DOI: 10.1016/J.Ajhg.2015.12.003 |
0.492 |
|
| 2016 |
Minikel EV, Vallabh SM, Lek M, Estrada K, Samocha KE, Sathirapongsasuti JF, McLean CY, Tung JY, Yu LP, Gambetti P, Blevins J, Zhang S, Cohen Y, Chen W, Yamada M, ... ... Mohlke KL, et al. Quantifying prion disease penetrance using large population control cohorts. Science Translational Medicine. 8: 322ra9. PMID 26791950 DOI: 10.1126/Scitranslmed.Aad5169 |
0.402 |
|
| 2016 |
Wen W, Kato N, Hwang JY, Guo X, Tabara Y, Li H, Dorajoo R, Yang X, Tsai FJ, Li S, Wu Y, Wu T, Kim S, Guo X, Liang J, ... ... Mohlke KL, et al. Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference. Scientific Reports. 6: 17958. PMID 26785701 DOI: 10.1038/Srep17958 |
0.536 |
|
| 2015 |
Roman TS, Marvelle AF, Fogarty MP, Vadlamudi S, Gonzalez AJ, Buchkovich ML, Huyghe JR, Fuchsberger C, Jackson AU, Wu Y, Civelek M, Lusis AJ, Gaulton KJ, Sethupathy P, Kangas AJ, ... ... Mohlke KL, et al. Multiple Hepatic Regulatory Variants at the GALNT2 GWAS Locus Associated with High-Density Lipoprotein Cholesterol. American Journal of Human Genetics. 97: 801-15. PMID 26637976 DOI: 10.1016/J.Ajhg.2015.10.016 |
0.815 |
|
| 2015 |
Gaulton KJ, Ferreira T, Lee Y, Raimondo A, Mägi R, Reschen ME, Mahajan A, Locke A, William Rayner N, Robertson N, Scott RA, Prokopenko I, Scott LJ, Green T, Sparso T, ... ... Mohlke KL, et al. Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci. Nature Genetics. PMID 26551672 DOI: 10.1038/Ng.3437 |
0.729 |
|
| 2015 |
Young KL, Graff M, North KE, Richardson AS, Mohlke KL, Lange LA, Lange EM, Harris KM, Gordon-Larsen P. Interaction of smoking and obesity susceptibility loci on adolescent BMI: The National Longitudinal Study of Adolescent to Adult Health. Bmc Genetics. 16: 131. PMID 26537541 DOI: 10.1186/S12863-015-0289-6 |
0.383 |
|
| 2015 |
Winkler TW, Justice AE, Graff M, Barata L, Feitosa MF, Chu S, Czajkowski J, Esko T, Fall T, Kilpeläinen TO, Lu Y, Mägi R, Mihailov E, Pers TH, Rüeger S, ... ... Mohlke KL, et al. The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. Plos Genetics. 11: e1005378. PMID 26426971 DOI: 10.1371/Journal.Pgen.1005378 |
0.42 |
|
| 2015 |
Kato N, Loh M, Takeuchi F, Verweij N, Wang X, Zhang W, Kelly TN, Saleheen D, Lehne B, Mateo Leach I, Drong AW, Abbott J, Wahl S, Tan ST, Scott WR, ... ... Mohlke KL, et al. Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. Nature Genetics. 47: 1282-93. PMID 26390057 DOI: 10.1038/Ng.3405 |
0.418 |
|
| 2015 |
Buchkovich ML, Eklund K, Duan Q, Li Y, Mohlke KL, Furey TS. Removing reference mapping biases using limited or no genotype data identifies allelic differences in protein binding at disease-associated loci. Bmc Medical Genomics. 8: 43. PMID 26210163 DOI: 10.1186/S12920-015-0117-X |
0.467 |
|
| 2015 |
Mohlke KL, Boehnke M. Recent advances in understanding the genetic architecture of type 2 diabetes. Human Molecular Genetics. 24: R85-92. PMID 26160912 DOI: 10.1093/Hmg/Ddv264 |
0.525 |
|
| 2015 |
Joshi PK, Esko T, Mattsson H, Eklund N, Gandin I, Nutile T, Jackson AU, Schurmann C, Smith AV, Zhang W, Okada Y, Stančáková A, Faul JD, Zhao W, Bartz TM, ... ... Mohlke KL, et al. Directional dominance on stature and cognition in diverse human populations. Nature. 523: 459-62. PMID 26131930 DOI: 10.1038/Nature14618 |
0.444 |
|
| 2015 |
Schmidt EM, Zhang J, Zhou W, Chen J, Mohlke KL, Chen YE, Willer CJ. GREGOR: evaluating global enrichment of trait-associated variants in epigenomic features using a systematic, data-driven approach. Bioinformatics (Oxford, England). PMID 25886982 DOI: 10.1093/Bioinformatics/Btv201 |
0.497 |
|
| 2015 |
Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, Powell C, Vedantam S, Buchkovich ML, Yang J, Croteau-Chonka DC, Esko T, Fall T, Ferreira T, Gustafsson S, ... ... Mohlke KL, et al. Genetic studies of body mass index yield new insights for obesity biology. Nature. 518: 197-206. PMID 25673413 DOI: 10.1038/Nature14177 |
0.719 |
|
| 2015 |
Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, Locke AE, Mägi R, Strawbridge RJ, Pers TH, Fischer K, Justice AE, Workalemahu T, Wu JM, Buchkovich ML, Heard-Costa NL, Roman TS, ... ... Mohlke KL, et al. New genetic loci link adipose and insulin biology to body fat distribution. Nature. 518: 187-96. PMID 25673412 DOI: 10.1038/Nature14132 |
0.739 |
|
| 2015 |
Wessel J, Chu AY, Willems SM, Wang S, Yaghootkar H, Brody JA, Dauriz M, Hivert MF, Raghavan S, Lipovich L, Hidalgo B, Fox K, Huffman JE, An P, Lu Y, ... ... Mohlke KL, et al. Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility. Nature Communications. 6: 5897. PMID 25631608 DOI: 10.1038/Ncomms6897 |
0.432 |
|
| 2015 |
Mahajan A, Sim X, Ng HJ, Manning A, Rivas MA, Highland HM, Locke AE, Grarup N, Im HK, Cingolani P, Flannick J, Fontanillas P, Fuchsberger C, Gaulton KJ, Teslovich TM, ... ... Mohlke KL, et al. Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus. Plos Genetics. 11: e1004876. PMID 25625282 DOI: 10.1371/Journal.Pgen.1004876 |
0.744 |
|
| 2015 |
Li J, Shi J, Huang W, Sun J, Wu Y, Duan Q, Luo J, Lange LA, Gordon-Larsen P, Zheng SL, Yuan W, Wang Y, Popkin BM, Mo Z, Xu J, ... ... Mohlke KL, et al. Variant Near FGF5 Has Stronger Effects on Blood Pressure in Chinese With a Higher Body Mass Index. American Journal of Hypertension. 28: 1031-7. PMID 25618516 DOI: 10.1093/Ajh/Hpu263 |
0.351 |
|
| 2015 |
He M, Xu M, Zhang B, Liang J, Chen P, Lee JY, Johnson TA, Li H, Yang X, Dai J, Liang L, Gui L, Qi Q, Huang J, Li Y, ... ... Mohlke KL, et al. Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci. Human Molecular Genetics. 24: 1791-800. PMID 25429064 DOI: 10.1093/Hmg/Ddu583 |
0.554 |
|
| 2015 |
Hwang JY, Sim X, Wu Y, Liang J, Tabara Y, Hu C, Hara K, Tam CH, Cai Q, Zhao Q, Jee S, Takeuchi F, Go MJ, Ong RT, Ohkubo T, ... ... Mohlke KL, et al. Genome-wide association meta-analysis identifies novel variants associated with fasting plasma glucose in East Asians. Diabetes. 64: 291-8. PMID 25187374 DOI: 10.2337/Db14-0563 |
0.475 |
|
| 2014 |
Huang KC, Sun W, Wu Y, Chen M, Mohlke KL, Lange LA, Li Y. Association studies with imputed variants using expectation-maximization likelihood-ratio tests. Plos One. 9: e110679. PMID 25383782 DOI: 10.1371/Journal.Pone.0110679 |
0.374 |
|
| 2014 |
Wood AR, Esko T, Yang J, Vedantam S, Pers TH, Gustafsson S, Chu AY, Estrada K, Luan J, Kutalik Z, Amin N, Buchkovich ML, Croteau-Chonka DC, Day FR, Duan Y, ... ... Mohlke KL, et al. Defining the role of common variation in the genomic and biological architecture of adult human height. Nature Genetics. 46: 1173-86. PMID 25282103 DOI: 10.1038/Ng.3097 |
0.748 |
|
| 2014 |
Fogarty MP, Cannon ME, Vadlamudi S, Gaulton KJ, Mohlke KL. Identification of a regulatory variant that binds FOXA1 and FOXA2 at the CDC123/CAMK1D type 2 diabetes GWAS locus. Plos Genetics. 10: e1004633. PMID 25211022 DOI: 10.1371/Journal.Pgen.1004633 |
0.715 |
|
| 2014 |
Qi Q, Kilpeläinen TO, Downer MK, Tanaka T, Smith CE, Sluijs I, Sonestedt E, Chu AY, Renström F, Lin X, Ängquist LH, Huang J, Liu Z, Li Y, Asif Ali M, ... ... Mohlke KL, et al. FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals. Human Molecular Genetics. 23: 6961-72. PMID 25104851 DOI: 10.1093/Hmg/Ddu411 |
0.461 |
|
| 2014 |
Lo KS, Vadlamudi S, Fogarty MP, Mohlke KL, Lettre G. Strategies to fine-map genetic associations with lipid levels by combining epigenomic annotations and liver-specific transcription profiles. Genomics. 104: 105-12. PMID 24997396 DOI: 10.1016/J.Ygeno.2014.04.006 |
0.5 |
|
| 2014 |
Zubair N, Mayer-Davis EJ, Mendez MA, Mohlke KL, North KE, Adair LS. Genetic risk score and adiposity interact to influence triglyceride levels in a cohort of Filipino women. Nutrition & Diabetes. 4: e118. PMID 24932782 DOI: 10.1038/Nutd.2014.16 |
0.42 |
|
| 2014 |
Wen W, Zheng W, Okada Y, Takeuchi F, Tabara Y, Hwang JY, Dorajoo R, Li H, Tsai FJ, Yang X, He J, Wu Y, He M, Zhang Y, Liang J, ... ... Mohlke KL, et al. Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index. Human Molecular Genetics. 23: 5492-504. PMID 24861553 DOI: 10.1093/Hmg/Ddu248 |
0.548 |
|
| 2014 |
Liu CT, Buchkovich ML, Winkler TW, Heid IM, Borecki IB, Fox CS, Mohlke KL, North KE, Adrienne Cupples L. Multi-ethnic fine-mapping of 14 central adiposity loci. Human Molecular Genetics. 23: 4738-44. PMID 24760767 DOI: 10.1093/Hmg/Ddu183 |
0.539 |
|
| 2014 |
Flannick J, Thorleifsson G, Beer NL, Jacobs SB, Grarup N, Burtt NP, Mahajan A, Fuchsberger C, Atzmon G, Benediktsson R, Blangero J, Bowden DW, Brandslund I, Brosnan J, Burslem F, ... ... Mohlke KL, et al. Loss-of-function mutations in SLC30A8 protect against type 2 diabetes. Nature Genetics. 46: 357-63. PMID 24584071 DOI: 10.1038/Ng.2915 |
0.418 |
|
| 2014 |
Xi B, Takeuchi F, Meirhaeghe A, Kato N, Chambers JC, Morris AP, Cho YS, Zhang W, Mohlke KL, Kooner JS, Shu XO, Pan H, Tai ES, Pan H, Wu JY, et al. Associations of genetic variants in/near body mass index-associated genes with type 2 diabetes: a systematic meta-analysis. Clinical Endocrinology. 81: 702-10. PMID 24528214 DOI: 10.1111/Cen.12428 |
0.479 |
|
| 2014 |
Mahajan A, Go MJ, Zhang W, Below JE, Gaulton KJ, Ferreira T, Horikoshi M, Johnson AD, Ng MC, Prokopenko I, ... ... Mohlke KL, et al. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nature Genetics. 46: 234-44. PMID 24509480 DOI: 10.1038/Ng.2897 |
0.751 |
|
| 2014 |
Kulzer JR, Stitzel ML, Morken MA, Huyghe JR, Fuchsberger C, Kuusisto J, Laakso M, Boehnke M, Collins FS, Mohlke KL. A common functional regulatory variant at a type 2 diabetes locus upregulates ARAP1 expression in the pancreatic beta cell. American Journal of Human Genetics. 94: 186-97. PMID 24439111 DOI: 10.1016/J.Ajhg.2013.12.011 |
0.52 |
|
| 2014 |
Dimas AS, Lagou V, Barker A, Knowles JW, Mägi R, Hivert MF, Benazzo A, Rybin D, Jackson AU, Stringham HM, Song C, Fischer-Rosinsky A, Boesgaard TW, Grarup N, Abbasi FA, ... ... Mohlke KL, et al. Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity. Diabetes. 63: 2158-71. PMID 24296717 DOI: 10.2337/Db13-0949 |
0.38 |
|
| 2014 |
Wu Y, Gao H, Li H, Tabara Y, Nakatochi M, Chiu YF, Park EJ, Wen W, Adair LS, Borja JB, Cai Q, Chang YC, Chen P, Croteau-Chonka DC, Fogarty MP, ... ... Mohlke KL, et al. A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2. Human Molecular Genetics. 23: 1108-19. PMID 24105470 DOI: 10.1093/Hmg/Ddt488 |
0.754 |
|
| 2014 |
Richardson AS, North KE, Graff M, Young KM, Mohlke KL, Lange LA, Lange EM, Harris KM, Gordon-Larsen P. Moderate to vigorous physical activity interactions with genetic variants and body mass index in a large US ethnically diverse cohort. Pediatric Obesity. 9: e35-46. PMID 23529959 DOI: 10.1111/J.2047-6310.2013.00152.X |
0.418 |
|
| 2014 |
Mohlke KL, Lindgren CM. Genome-wide association studies of obesity and related traits Frontiers in Diabetes. 23: 58-70. DOI: 10.1159/000362467 |
0.463 |
|
| 2013 |
Willer CJ, Schmidt EM, Sengupta S, Peloso GM, Gustafsson S, Kanoni S, Ganna A, Chen J, Buchkovich ML, Mora S, Beckmann JS, Bragg-Gresham JL, Chang HY, Demirkan A, ... ... Mohlke KL, et al. Discovery and refinement of loci associated with lipid levels. Nature Genetics. 45: 1274-83. PMID 24097068 DOI: 10.1038/Ng.2797 |
0.477 |
|
| 2013 |
Do R, Willer CJ, Schmidt EM, Sengupta S, Gao C, Peloso GM, Gustafsson S, Kanoni S, Ganna A, Chen J, Buchkovich ML, Mora S, Beckmann JS, Bragg-Gresham JL, Chang HY, ... ... Mohlke KL, et al. Common variants associated with plasma triglycerides and risk for coronary artery disease. Nature Genetics. 45: 1345-52. PMID 24097064 DOI: 10.1038/Ng.2795 |
0.4 |
|
| 2013 |
Wu Y, Marvelle AF, Li J, Croteau-Chonka DC, Feranil AB, Kuzawa CW, Li Y, Adair LS, Mohlke KL. Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels. Journal of Lipid Research. 54: 3198-205. PMID 24023260 DOI: 10.1194/Jlr.P042077 |
0.815 |
|
| 2013 |
Kelly TN, Takeuchi F, Tabara Y, Edwards TL, Kim YJ, Chen P, Li H, Wu Y, Yang CF, Zhang Y, Gu D, Katsuya T, Ohkubo T, Gao YT, Go MJ, ... ... Mohlke K, et al. Genome-wide association study meta-analysis reveals transethnic replication of mean arterial and pulse pressure loci. Hypertension. 62: 853-9. PMID 24001895 DOI: 10.1161/Hypertensionaha.113.01148 |
0.433 |
|
| 2013 |
Ahmad S, Rukh G, Varga TV, Ali A, Kurbasic A, Shungin D, Ericson U, Koivula RW, Chu AY, Rose LM, Ganna A, Qi Q, StanÄáková A, Sandholt CH, Elks CE, ... ... Mohlke KL, et al. Gene × physical activity interactions in obesity: combined analysis of 111,421 individuals of European ancestry. Plos Genetics. 9: e1003607. PMID 23935507 DOI: 10.1371/Journal.Pgen.1003607 |
0.452 |
|
| 2013 |
Yaghootkar H, Lamina C, Scott RA, Dastani Z, Hivert MF, Warren LL, Stancáková A, Buxbaum SG, Lyytikäinen LP, Henneman P, Wu Y, Cheung CY, Pankow JS, Jackson AU, Gustafsson S, ... ... Mohlke KL, et al. Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes. Diabetes. 62: 3589-98. PMID 23835345 DOI: 10.2337/Db13-0128 |
0.382 |
|
| 2013 |
Randall JC, Winkler TW, Kutalik Z, Berndt SI, Jackson AU, Monda KL, Kilpeläinen TO, Esko T, Mägi R, Li S, Workalemahu T, Feitosa MF, Croteau-Chonka DC, Day FR, Fall T, ... ... Mohlke KL, et al. Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. Plos Genetics. 9: e1003500. PMID 23754948 DOI: 10.1371/Journal.Pgen.1003500 |
0.742 |
|
| 2013 |
Croteau-Chonka DC, Lange LA, Lee NR, Adair LS, Mohlke KL. Replication of LIN28B SNP association with age of menarche in young Filipino women. Pediatric Obesity. 8: e50-3. PMID 23740805 DOI: 10.1111/J.2047-6310.2013.00178.X |
0.741 |
|
| 2013 |
Berndt SI, Gustafsson S, Mägi R, Ganna A, Wheeler E, Feitosa MF, Justice AE, Monda KL, Croteau-Chonka DC, Day FR, Esko T, Fall T, Ferreira T, Gentilini D, Jackson AU, ... ... Mohlke KL, et al. Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nature Genetics. 45: 501-12. PMID 23563607 DOI: 10.1038/Ng.2606 |
0.75 |
|
| 2013 |
Mahendran Y, Vangipurapu J, Cederberg H, Stancáková A, Pihlajamäki J, Soininen P, Kangas AJ, Paananen J, Civelek M, Saleem NK, Pajukanta P, Lusis AJ, Bonnycastle LL, Morken MA, Collins FS, ... Mohlke KL, et al. Association of ketone body levels with hyperglycemia and type 2 diabetes in 9,398 Finnish men. Diabetes. 62: 3618-26. PMID 23557707 DOI: 10.2337/Db12-1363 |
0.401 |
|
| 2013 |
Wu Y, Waite LL, Jackson AU, Sheu WH, Buyske S, Absher D, Arnett DK, Boerwinkle E, Bonnycastle LL, Carty CL, Cheng I, Cochran B, Croteau-Chonka DC, Dumitrescu L, Eaton CB, ... ... Mohlke KL, et al. Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained. Plos Genetics. 9: e1003379. PMID 23555291 DOI: 10.1371/Journal.Pgen.1003379 |
0.767 |
|
| 2013 |
Fogarty MP, Panhuis TM, Vadlamudi S, Buchkovich ML, Mohlke KL. Allele-specific transcriptional activity at type 2 diabetes-associated single nucleotide polymorphisms in regions of pancreatic islet open chromatin at the JAZF1 locus. Diabetes. 62: 1756-62. PMID 23328127 DOI: 10.2337/Db12-0972 |
0.45 |
|
| 2013 |
Duan Q, Liu EY, Croteau-Chonka DC, Mohlke KL, Li Y. A comprehensive SNP and indel imputability database. Bioinformatics (Oxford, England). 29: 528-31. PMID 23292738 DOI: 10.1093/Bioinformatics/Bts724 |
0.739 |
|
| 2013 |
Huyghe JR, Jackson AU, Fogarty MP, Buchkovich ML, StanÄáková A, Stringham HM, Sim X, Yang L, Fuchsberger C, Cederberg H, Chines PS, Teslovich TM, Romm JM, Ling H, McMullen I, ... ... Mohlke KL, et al. Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion. Nature Genetics. 45: 197-201. PMID 23263489 DOI: 10.1038/Ng.2507 |
0.471 |
|
| 2013 |
Horikoshi M, Yaghootkar H, Mook-Kanamori DO, Sovio U, Taal HR, Hennig BJ, Bradfield JP, St Pourcain B, Evans DM, Charoen P, Kaakinen M, Cousminer DL, Lehtimäki T, Kreiner-Møller E, Warrington NM, ... ... Mohlke KL, et al. New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism. Nature Genetics. 45: 76-82. PMID 23202124 DOI: 10.1038/Ng.2477 |
0.468 |
|
| 2013 |
Ahmad S, Rukh G, Varga TV, Ali A, Kurbasic A, Shungin D, Ericson U, Koivula RW, Chu AY, Rose LM, Ganna A, Qi Q, Stančáková A, Sandholt CH, Elks CE, ... ... Mohlke KL, et al. Meta-analyzed single SNP interactions with physical activity* on BMI. Plos Genetics. DOI: 10.1371/Journal.Pgen.1003607.T002 |
0.376 |
|
| 2013 |
Wu Y, Waite LL, Jackson AU, Sheu WH, Buyske S, Absher D, Arnett DK, Boerwinkle E, Bonnycastle LL, Carty CL, Cheng I, Cochran B, Croteau-Chonka DC, Dumitrescu L, Eaton CB, ... ... Mohlke KL, et al. Lipid loci with multiple signals in Europeans. Plos Genetics. DOI: 10.1371/Journal.Pgen.1003379.T002 |
0.678 |
|
| 2012 |
Graff M, North KE, Mohlke KL, Lange LA, Luo J, Harris KM, Young KL, Richardson AS, Lange EM, Gordon-Larsen P. Estimation of genetic effects on BMI during adolescence in an ethnically diverse cohort: The National Longitudinal Study of Adolescent Health. Nutrition & Diabetes. 2: e47. PMID 23168566 DOI: 10.1038/Nutd.2012.20 |
0.353 |
|
| 2012 |
Mohlke KL, Scott LJ. What will diabetes genomes tell us? Current Diabetes Reports. 12: 643-50. PMID 22983892 DOI: 10.1007/S11892-012-0321-4 |
0.486 |
|
| 2012 |
Yang J, Loos RJ, Powell JE, Medland SE, Speliotes EK, Chasman DI, Rose LM, Thorleifsson G, Steinthorsdottir V, Mägi R, Waite L, Smith AV, Yerges-Armstrong LM, Monda KL, Hadley D, ... ... Mohlke KL, et al. FTO genotype is associated with phenotypic variability of body mass index. Nature. 490: 267-72. PMID 22982992 DOI: 10.1038/Nature11401 |
0.445 |
|
| 2012 |
Avery CL, Sethupathy P, Buyske S, He Q, Lin DY, Arking DE, Carty CL, Duggan D, Fesinmeyer MD, Hindorff LA, Jeff JM, Klein L, Patton KK, Peters U, Shohet RV, ... ... Mohlke KL, et al. Fine-mapping and initial characterization of QT interval loci in African Americans. Plos Genetics. 8: e1002870. PMID 22912591 DOI: 10.1371/Journal.Pgen.1002870 |
0.495 |
|
| 2012 |
Scott RA, Lagou V, Welch RP, Wheeler E, Montasser ME, Luan J, Mägi R, Strawbridge RJ, Rehnberg E, Gustafsson S, Kanoni S, Rasmussen-Torvik LJ, Yengo L, Lecoeur C, Shungin D, ... ... Mohlke KL, et al. Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nature Genetics. 44: 991-1005. PMID 22885924 DOI: 10.1038/Ng.2385 |
0.541 |
|
| 2012 |
Morris AP, Voight BF, Teslovich TM, Ferreira T, Segrè AV, Steinthorsdottir V, Strawbridge RJ, Khan H, Grallert H, Mahajan A, Prokopenko I, Kang HM, Dina C, Esko T, Fraser RM, ... ... Mohlke KL, et al. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nature Genetics. 44: 981-90. PMID 22885922 DOI: 10.1038/Ng.2383 |
0.487 |
|
| 2012 |
Perry JR, Voight BF, Yengo L, Amin N, Dupuis J, Ganser M, Grallert H, Navarro P, Li M, Qi L, Steinthorsdottir V, Scott RA, Almgren P, Arking DE, Aulchenko Y, ... ... Mohlke KL, et al. Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. Plos Genetics. 8: e1002741. PMID 22693455 DOI: 10.1371/Journal.Pgen.1002741 |
0.435 |
|
| 2012 |
Manning AK, Hivert MF, Scott RA, Grimsby JL, Bouatia-Naji N, Chen H, Rybin D, Liu CT, Bielak LF, Prokopenko I, Amin N, Barnes D, Cadby G, Hottenga JJ, Ingelsson E, ... ... Mohlke KL, et al. A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nature Genetics. 44: 659-69. PMID 22581228 DOI: 10.1038/Ng.2274 |
0.459 |
|
| 2012 |
Buyske S, Wu Y, Carty CL, Cheng I, Assimes TL, Dumitrescu L, Hindorff LA, Mitchell S, Ambite JL, Boerwinkle E, Buzkova P, Carlson CS, Cochran B, Duggan D, Eaton CB, ... ... Mohlke KL, et al. Evaluation of the metabochip genotyping array in African Americans and implications for fine mapping of GWAS-identified loci: the PAGE study. Plos One. 7: e35651. PMID 22539988 DOI: 10.1371/Journal.Pone.0035651 |
0.527 |
|
| 2012 |
Dastani Z, Hivert MF, Timpson N, Perry JR, Yuan X, Scott RA, Henneman P, Heid IM, Kizer JR, Lyytikäinen LP, Fuchsberger C, Tanaka T, Morris AP, Small K, Isaacs A, ... ... Mohlke KL, et al. Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. Plos Genetics. 8: e1002607. PMID 22479202 DOI: 10.1371/Journal.Pgen.1002607 |
0.749 |
|
| 2012 |
Willer CJ, Mohlke KL. Finding genes and variants for lipid levels after genome-wide association analysis. Current Opinion in Lipidology. 23: 98-103. PMID 22418572 DOI: 10.1097/Mol.0B013E328350Fad2 |
0.452 |
|
| 2012 |
Palmer ND, McDonough CW, Hicks PJ, Roh BH, Wing MR, An SS, Hester JM, Cooke JN, Bostrom MA, Rudock ME, Talbert ME, Lewis JP, Ferrara A, ... ... Mohlke KL, et al. A genome-wide association search for type 2 diabetes genes in African Americans. Plos One. 7: e29202. PMID 22238593 DOI: 10.1371/Journal.Pone.0029202 |
0.553 |
|
| 2012 |
Cho YS, Chen CH, Hu C, Long J, Ong RT, Sim X, Takeuchi F, Wu Y, Go MJ, Yamauchi T, Chang YC, Kwak SH, Ma RC, Yamamoto K, Adair LS, ... ... Mohlke KL, et al. Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. Nature Genetics. 44: 67-72. PMID 22158537 DOI: 10.1038/Ng.1019 |
0.458 |
|
| 2012 |
Croteau-Chonka DC, Wu Y, Li Y, Fogarty MP, Lange LA, Kuzawa CW, McDade TW, Borja JB, Luo J, AbdelBaky O, Combs TP, Adair LS, Lange EM, Mohlke KL. Population-specific coding variant underlies genome-wide association with adiponectin level. Human Molecular Genetics. 21: 463-71. PMID 22010046 DOI: 10.1093/Hmg/Ddr480 |
0.763 |
|
| 2012 |
Wu Y, McDade TW, Kuzawa CW, Borja J, Li Y, Adair LS, Mohlke KL, Lange LA. Genome-wide association with C-reactive protein levels in CLHNS: evidence for the CRP and HNF1A loci and their interaction with exposure to a pathogenic environment. Inflammation. 35: 574-83. PMID 21647738 DOI: 10.1007/S10753-011-9348-Y |
0.548 |
|
| 2011 |
Kilpeläinen TO, Qi L, Brage S, Sharp SJ, Sonestedt E, Demerath E, Ahmad T, Mora S, Kaakinen M, Sandholt CH, Holzapfel C, Autenrieth CS, Hyppönen E, Cauchi S, He M, ... ... Mohlke KL, et al. Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children. Plos Medicine. 8: e1001116. PMID 22069379 DOI: 10.1371/Journal.Pmed.1001116 |
0.347 |
|
| 2011 |
Curocichin G, Wu Y, McDade TW, Kuzawa CW, Borja JB, Qin L, Lange EM, Adair LS, Lange LA, Mohlke KL. Single-nucleotide polymorphisms at five loci are associated with C-reactive protein levels in a cohort of Filipino young adults. Journal of Human Genetics. 56: 823-7. PMID 21937998 DOI: 10.1038/Jhg.2011.106 |
0.538 |
|
| 2011 |
Ehret GB, Munroe PB, Rice KM, Bochud M, Johnson AD, Chasman DI, Smith AV, Tobin MD, Verwoert GC, Hwang SJ, Pihur V, Vollenweider P, O'Reilly PF, Amin N, ... ... Mohlke KL, et al. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature. 478: 103-9. PMID 21909115 DOI: 10.1038/Nature10405 |
0.337 |
|
| 2011 |
Kilpeläinen TO, Den Hoed M, Ong KK, Grøntved A, Brage S, Jameson K, Cooper C, Khaw KT, Ekelund U, Wareham NJ, Loos RJF, Freathy RM, Mook-Kanamori DO, Sovio U, Prokopenko I, ... ... Mohlke KL, et al. Obesity-susceptibility loci have a limited influence on birth weight: A meta-analysis of up to 28,219 individuals American Journal of Clinical Nutrition. 93: 851-860. PMID 21248185 DOI: 10.3945/ajcn.110.000828 |
0.342 |
|
| 2011 |
Croteau-Chonka DC, Marvelle AF, Lange EM, Lee NR, Adair LS, Lange LA, Mohlke KL. Genome-wide association study of anthropometric traits and evidence of interactions with age and study year in Filipino women. Obesity (Silver Spring, Md.). 19: 1019-27. PMID 20966902 DOI: 10.1038/Oby.2010.256 |
0.825 |
|
| 2010 |
Speliotes EK, Willer CJ, Berndt SI, Monda KL, Thorleifsson G, Jackson AU, Lango Allen H, Lindgren CM, Luan J, Mägi R, Randall JC, Vedantam S, Winkler TW, Qi L, Workalemahu T, ... ... Mohlke KL, et al. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nature Genetics. 42: 937-48. PMID 20935630 DOI: 10.1038/Ng.686 |
0.504 |
|
| 2010 |
Heid IM, Jackson AU, Randall JC, Winkler TW, Qi L, Steinthorsdottir V, Thorleifsson G, Zillikens MC, Speliotes EK, Mägi R, Workalemahu T, White CC, Bouatia-Naji N, Harris TB, Berndt SI, ... ... Mohlke KL, et al. Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nature Genetics. 42: 949-60. PMID 20935629 DOI: 10.1038/Ng.685 |
0.479 |
|
| 2010 |
Lango Allen H, Estrada K, Lettre G, Berndt SI, Weedon MN, Rivadeneira F, Willer CJ, Jackson AU, Vedantam S, Raychaudhuri S, Ferreira T, Wood AR, Weyant RJ, Segrè AV, Speliotes EK, ... ... Mohlke KL, et al. Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature. 467: 832-8. PMID 20881960 DOI: 10.1038/Nature09410 |
0.537 |
|
| 2010 |
Wu Y, Li Y, Lange EM, Croteau-Chonka DC, Kuzawa CW, McDade TW, Qin L, Curocichin G, Borja JB, Lange LA, Adair LS, Mohlke KL. Genome-wide association study for adiponectin levels in Filipino women identifies CDH13 and a novel uncommon haplotype at KNG1-ADIPOQ. Human Molecular Genetics. 19: 4955-64. PMID 20876611 DOI: 10.1093/Hmg/Ddq423 |
0.787 |
|
| 2010 |
Waterworth DM, Ricketts SL, Song K, Chen L, Zhao JH, Ripatti S, Aulchenko YS, Zhang W, Yuan X, Lim N, Luan J, Ashford S, Wheeler E, Young EH, Hadley D, ... ... Mohlke KL, et al. Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 2264-76. PMID 20864672 DOI: 10.1161/Atvbaha.109.201020 |
0.398 |
|
| 2010 |
Soranzo N, Sanna S, Wheeler E, Gieger C, Radke D, Dupuis J, Bouatia-Naji N, Langenberg C, Prokopenko I, Stolerman E, Sandhu MS, Heeney MM, Devaney JM, Reilly MP, Ricketts SL, ... ... Mohlke KL, et al. Common variants at 10 genomic loci influence hemoglobin Aâ‚(C) levels via glycemic and nonglycemic pathways. Diabetes. 59: 3229-39. PMID 20858683 DOI: 10.2337/Db10-0502 |
0.516 |
|
| 2010 |
Westrick RJ, Mohlke KL, Korepta LM, Yang AY, Zhu G, Manning SL, Winn ME, Dougherty KM, Ginsburg D. Spontaneous Irs1 passenger mutation linked to a gene-targeted SerpinB2 allele. Proceedings of the National Academy of Sciences of the United States of America. 107: 16904-9. PMID 20837540 DOI: 10.1073/Pnas.1012050107 |
0.317 |
|
| 2010 |
Teslovich TM, Musunuru K, Smith AV, Edmondson AC, Stylianou IM, Koseki M, Pirruccello JP, Ripatti S, Chasman DI, Willer CJ, Johansen CT, Fouchier SW, Isaacs A, Peloso GM, Barbalic M, ... ... Mohlke KL, et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature. 466: 707-13. PMID 20686565 DOI: 10.1038/Nature09270 |
0.744 |
|
| 2010 |
Voight BF, Scott LJ, Steinthorsdottir V, Morris AP, Dina C, Welch RP, Zeggini E, Huth C, Aulchenko YS, Thorleifsson G, McCulloch LJ, Ferreira T, Grallert H, Amin N, Wu G, ... ... Mohlke KL, et al. Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nature Genetics. 42: 579-89. PMID 20581827 DOI: 10.1038/Ng.609 |
0.486 |
|
| 2010 |
Furberg H, Kim Y, Dackor J, Boerwinkle E, Franceschini N, Ardissino D, Bernardinelli L, Mannucci PM, Mauri F, Merlini PA, Absher D, Assimes TL, Fortmann SP, Iribarren C, Knowles JW, ... ... Mohlke KL, et al. Genome-wide meta-analyses identify multiple loci associated with smoking behavior Nature Genetics. 42: 441-447. PMID 20418890 DOI: 10.1038/Ng.571 |
0.448 |
|
| 2010 |
Freathy RM, Mook-Kanamori DO, Sovio U, Prokopenko I, Timpson NJ, Berry DJ, Warrington NM, Widen E, Hottenga JJ, Kaakinen M, Lange LA, Bradfield JP, Kerkhof M, Marsh JA, Mägi R, ... ... Mohlke KL, et al. Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight. Nature Genetics. 42: 430-5. PMID 20372150 DOI: 10.1038/Ng.567 |
0.349 |
|
| 2010 |
Ingelsson E, Langenberg C, Hivert MF, Prokopenko I, Lyssenko V, Dupuis J, Mägi R, Sharp S, Jackson AU, Assimes TL, Shrader P, Knowles JW, Zethelius B, Abbasi FA, Bergman RN, ... ... Mohlke KL, et al. Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans. Diabetes. 59: 1266-75. PMID 20185807 DOI: 10.2337/Db09-1568 |
0.343 |
|
| 2010 |
Fogarty MP, Xiao R, Prokunina-Olsson L, Scott LJ, Mohlke KL. Allelic expression imbalance at high-density lipoprotein cholesterol locus MMAB-MVK. Human Molecular Genetics. 19: 1921-9. PMID 20159775 DOI: 10.1093/Hmg/Ddq067 |
0.524 |
|
| 2010 |
Lange LA, Croteau-Chonka DC, Marvelle AF, Qin L, Gaulton KJ, Kuzawa CW, McDade TW, Wang Y, Li Y, Levy S, Borja JB, Lange EM, Adair LS, Mohlke KL. Genome-wide association study of homocysteine levels in Filipinos provides evidence for CPS1 in women and a stronger MTHFR effect in young adults. Human Molecular Genetics. 19: 2050-8. PMID 20154341 DOI: 10.1093/Hmg/Ddq062 |
0.807 |
|
| 2010 |
Gaulton KJ, Nammo T, Pasquali L, Simon JM, Giresi PG, Fogarty MP, Panhuis TM, Mieczkowski P, Secchi A, Bosco D, Berney T, Montanya E, Mohlke KL, Lieb JD, Ferrer J. A map of open chromatin in human pancreatic islets. Nature Genetics. 42: 255-9. PMID 20118932 DOI: 10.1038/Ng.530 |
0.677 |
|
| 2010 |
Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL, Bouatia-Naji N, Gloyn AL, Lindgren CM, Mägi R, Morris AP, Randall J, Johnson T, ... ... Mohlke KL, et al. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nature Genetics. 42: 105-16. PMID 20081858 DOI: 10.1038/Ng.520 |
0.424 |
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| 2010 |
Saxena R, Hivert MF, Langenberg C, Tanaka T, Pankow JS, Vollenweider P, Lyssenko V, Bouatia-Naji N, Dupuis J, Jackson AU, Kao WH, Li M, Glazer NL, Manning AK, Luan J, ... ... Mohlke KL, et al. Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nature Genetics. 42: 142-8. PMID 20081857 DOI: 10.1038/Ng.521 |
0.419 |
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| 2010 |
Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL, Bouatia-Naji N, Gloyn AL, Lindgren CM, Mägi R, Morris AP, Randall J, Johnson T, ... ... Mohlke KL, et al. Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk Nature Genetics. 42: 464-464. DOI: 10.1038/Ng0510-464A |
0.361 |
|
| 2009 |
Heid IM, Huth C, Loos RJ, Kronenberg F, Adamkova V, Anand SS, Ardlie K, Biebermann H, Bjerregaard P, Boeing H, Bouchard C, Ciullo M, Cooper JA, Corella D, Dina C, ... ... Mohlke KL, et al. Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design? Plos Genetics. 5: e1000694. PMID 19851442 DOI: 10.1371/Journal.Pgen.1000694 |
0.446 |
|
| 2009 |
Lindgren CM, Heid IM, Randall JC, Lamina C, Steinthorsdottir V, Qi L, Speliotes EK, Thorleifsson G, Willer CJ, Herrera BM, Jackson AU, Lim N, Scheet P, Soranzo N, Amin N, ... ... Mohlke KL, et al. Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. Plos Genetics. 5: e1000508. PMID 19557161 DOI: 10.1371/Journal.Pgen.1000508 |
0.498 |
|
| 2009 |
Newton-Cheh C, Johnson T, Gateva V, Tobin MD, Bochud M, Coin L, Najjar SS, Zhao JH, Heath SC, Eyheramendy S, Papadakis K, Voight BF, Scott LJ, Zhang F, Farrall M, ... ... Mohlke KL, et al. Genome-wide association study identifies eight loci associated with blood pressure. Nature Genetics. 41: 666-76. PMID 19430483 DOI: 10.1038/Ng.361 |
0.39 |
|
| 2009 |
Liu Y, Sanoff HK, Cho H, Burd CE, Torrice C, Mohlke KL, Ibrahim JG, Thomas NE, Sharpless NE. INK4/ARF transcript expression is associated with chromosome 9p21 variants linked to atherosclerosis. Plos One. 4: e5027. PMID 19343170 DOI: 10.1371/Journal.Pone.0005027 |
0.493 |
|
| 2009 |
Zinman L, Liu HN, Sato C, Wakutani Y, Marvelle AF, Moreno D, Morrison KE, Mohlke KL, Bilbao J, Robertson J, Rogaeva E. A mechanism for low penetrance in an ALS family with a novel SOD1 deletion. Neurology. 72: 1153-9. PMID 19332692 DOI: 10.1212/01.wnl.0000345363.65799.35 |
0.743 |
|
| 2009 |
Willer CJ, Speliotes EK, Loos RJ, Li S, Lindgren CM, Heid IM, Berndt SI, Elliott AL, Jackson AU, Lamina C, Lettre G, Lim N, Lyon HN, McCarroll SA, Papadakis K, ... ... Mohlke KL, et al. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nature Genetics. 41: 25-34. PMID 19079261 DOI: 10.1038/Ng.287 |
0.479 |
|
| 2009 |
Prokopenko I, Langenberg C, Florez JC, Saxena R, Soranzo N, Thorleifsson G, Loos RJ, Manning AK, Jackson AU, Aulchenko Y, Potter SC, Erdos MR, Sanna S, Hottenga JJ, Wheeler E, ... ... Mohlke KL, et al. Variants in MTNR1B influence fasting glucose levels. Nature Genetics. 41: 77-81. PMID 19060907 DOI: 10.1038/Ng.290 |
0.502 |
|
| 2009 |
Kathiresan S, Willer CJ, Peloso GM, Demissie S, Musunuru K, Schadt EE, Kaplan L, Bennett D, Li Y, Tanaka T, Voight BF, Bonnycastle LL, Jackson AU, Crawford G, Surti A, ... ... Mohlke KL, et al. Common variants at 30 loci contribute to polygenic dyslipidemia. Nature Genetics. 41: 56-65. PMID 19060906 DOI: 10.1038/Ng.291 |
0.433 |
|
| 2008 |
Pomp D, Mohlke KL. Obesity genes: so close and yet so far... Journal of Biology. 7: 36. PMID 19046411 DOI: 10.1186/Jbiol93 |
0.386 |
|
| 2008 |
Mohlke KL. Nonsynonymous variants and fatty liver disease. Nature Genetics. 40: 1394-5. PMID 19029975 DOI: 10.1038/Ng1208-1394 |
0.321 |
|
| 2008 |
Mohlke KL, Boehnke M, Abecasis GR. Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants. Human Molecular Genetics. 17: R102-8. PMID 18852197 DOI: 10.1093/Hmg/Ddn275 |
0.491 |
|
| 2008 |
Gaulton KJ, Willer CJ, Li Y, Scott LJ, Conneely KN, Jackson AU, Duren WL, Chines PS, Narisu N, Bonnycastle LL, Luo J, Tong M, Sprau AG, Pugh EW, Doheny KF, ... ... Mohlke KL, et al. Comprehensive association study of type 2 diabetes and related quantitative traits with 222 candidate genes. Diabetes. 57: 3136-44. PMID 18678618 DOI: 10.2337/Db07-1731 |
0.692 |
|
| 2008 |
Chen WM, Erdos MR, Jackson AU, Saxena R, Sanna S, Silver KD, Timpson NJ, Hansen T, Orrù M, Grazia Piras M, Bonnycastle LL, Willer CJ, Lyssenko V, Shen H, Kuusisto J, ... ... Mohlke KL, et al. Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels. The Journal of Clinical Investigation. 118: 2620-8. PMID 18521185 DOI: 10.1172/Jci34566 |
0.451 |
|
| 2008 |
Loos RJ, Lindgren CM, Li S, Wheeler E, Zhao JH, Prokopenko I, Inouye M, Freathy RM, Attwood AP, Beckmann JS, Berndt SI, Jacobs KB, Chanock SJ, Hayes RB, ... ... Mohlke KL, et al. Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nature Genetics. 40: 768-75. PMID 18454148 DOI: 10.1038/ng.140 |
0.397 |
|
| 2008 |
Marvelle AF, Lange LA, Qin L, Adair LS, Mohlke KL. Association of FTO with obesity-related traits in the Cebu Longitudinal Health and Nutrition Survey (CLHNS) Cohort. Diabetes. 57: 1987-91. PMID 18426866 DOI: 10.2337/Db07-1700 |
0.801 |
|
| 2008 |
Lettre G, Jackson AU, Gieger C, Schumacher FR, Berndt SI, Sanna S, Eyheramendy S, Voight BF, Butler JL, Guiducci C, Illig T, Hackett R, Heid IM, Jacobs KB, Lyssenko V, ... ... Mohlke KL, et al. Identification of ten loci associated with height highlights new biological pathways in human growth. Nature Genetics. 40: 584-91. PMID 18391950 DOI: 10.1038/Ng.125 |
0.539 |
|
| 2008 |
Zeggini E, Scott LJ, Saxena R, Voight BF, Marchini JL, Hu T, de Bakker PI, Abecasis GR, Almgren P, Andersen G, Ardlie K, Boström KB, Bergman RN, Bonnycastle LL, Borch-Johnsen K, ... ... Mohlke KL, et al. Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nature Genetics. 40: 638-45. PMID 18372903 DOI: 10.1038/Ng.120 |
0.826 |
|
| 2008 |
Sanna S, Jackson AU, Nagaraja R, Willer CJ, Chen WM, Bonnycastle LL, Shen H, Timpson N, Lettre G, Usala G, Chines PS, Stringham HM, Scott LJ, Dei M, Lai S, ... ... Mohlke KL, et al. Common variants in the GDF5-UQCC region are associated with variation in human height. Nature Genetics. 40: 198-203. PMID 18193045 DOI: 10.1038/Ng.74 |
0.52 |
|
| 2008 |
Willer CJ, Sanna S, Jackson AU, Scuteri A, Bonnycastle LL, Clarke R, Heath SC, Timpson NJ, Najjar SS, Stringham HM, Strait J, Duren WL, Maschio A, Busonero F, Mulas A, ... ... Mohlke KL, et al. Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nature Genetics. 40: 161-9. PMID 18193043 DOI: 10.1038/Ng.76 |
0.49 |
|
| 2008 |
Franks PW, Rolandsson O, Debenham SL, Fawcett KA, Payne F, Dina C, Froguel P, Mohlke KL, Willer C, Olsson T, Wareham NJ, Hallmans G, Barroso I, Sandhu MS. Replication of the association between variants in WFS1 and risk of type 2 diabetes in European populations. Diabetologia. 51: 458-63. PMID 18040659 DOI: 10.1007/S00125-007-0887-6 |
0.445 |
|
| 2008 |
Franks PW, Rolandsson O, Debenham SL, Fawcett KA, Payne F, Dina C, Froguel P, Mohlke KL, Willer C, Olsson T, Wareham NJ, Hallmans G, Barroso I, Sandhu MS. Replication of the association between variants in WFS1 and risk of type 2 diabetes in European populations (Diabetologia DOI: 10.1007/s00125-007-0887-6) Diabetologia. 51: 523. DOI: 10.1007/S00125-007-0907-6 |
0.387 |
|
| 2007 |
Marvelle AF, Lange LA, Qin L, Wang Y, Lange EM, Adair LS, Mohlke KL. Comparison of ENCODE region SNPs between Cebu Filipino and Asian HapMap samples. Journal of Human Genetics. 52: 729-37. PMID 17636361 DOI: 10.1007/S10038-007-0175-9 |
0.81 |
|
| 2007 |
Scott LJ, Mohlke KL, Bonnycastle LL, Willer CJ, Li Y, Duren WL, Erdos MR, Stringham HM, Chines PS, Jackson AU, Prokunina-Olsson L, Ding CJ, Swift AJ, Narisu N, Hu T, et al. A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science (New York, N.Y.). 316: 1341-5. PMID 17463248 DOI: 10.1126/Science.1142382 |
0.575 |
|
| 2007 |
Gaulton KJ, Mohlke KL, Vision TJ. A computational system to select candidate genes for complex human traits. Bioinformatics (Oxford, England). 23: 1132-40. PMID 17237041 DOI: 10.1093/Bioinformatics/Btm001 |
0.657 |
|
| 2007 |
Willer CJ, Bonnycastle LL, Conneely KN, Duren WL, Jackson AU, Scott LJ, Narisu N, Chines PS, Skol A, Stringham HM, Petrie J, Erdos MR, Swift AJ, Enloe ST, Sprau AG, ... ... Mohlke KL, et al. Screening of 134 single nucleotide polymorphisms (SNPs) previously associated with type 2 diabetes replicates association with 12 SNPs in nine genes. Diabetes. 56: 256-64. PMID 17192490 DOI: 10.2337/Db06-0461 |
0.496 |
|
| 2006 |
Scott LJ, Bonnycastle LL, Willer CJ, Sprau AG, Jackson AU, Narisu N, Duren WL, Chines PS, Stringham HM, Erdos MR, Valle TT, Tuomilehto J, Bergman RN, Mohlke KL, Collins FS, et al. Association of transcription factor 7-like 2 (TCF7L2) variants with type 2 diabetes in a Finnish sample. Diabetes. 55: 2649-53. PMID 16936217 DOI: 10.2337/Db06-0341 |
0.48 |
|
| 2006 |
Bonnycastle LL, Willer CJ, Conneely KN, Jackson AU, Burrill CP, Watanabe RM, Chines PS, Narisu N, Scott LJ, Enloe ST, Swift AJ, Duren WL, Stringham HM, Erdos MR, Riebow NL, ... ... Mohlke KL, et al. Common variants in maturity-onset diabetes of the young genes contribute to risk of type 2 diabetes in Finns. Diabetes. 55: 2534-40. PMID 16936201 DOI: 10.2337/Db06-0178 |
0.446 |
|
| 2006 |
Willer CJ, Scott LJ, Bonnycastle LL, Jackson AU, Chines P, Pruim R, Bark CW, Tsai YY, Pugh EW, Doheny KF, Kinnunen L, Mohlke KL, Valle TT, Bergman RN, Tuomilehto J, et al. Tag SNP selection for Finnish individuals based on the CEPH Utah HapMap database. Genetic Epidemiology. 30: 180-90. PMID 16374835 DOI: 10.1002/Gepi.20131 |
0.458 |
|
| 2005 |
Mohlke KL, Jackson AU, Scott LJ, Peck EC, Suh YD, Chines PS, Watanabe RM, Buchanan TA, Conneely KN, Erdos MR, Narisu N, Enloe S, Valle TT, Tuomilehto J, Bergman RN, et al. Mitochondrial polymorphisms and susceptibility to type 2 diabetes-related traits in Finns. Human Genetics. 118: 245-54. PMID 16142453 DOI: 10.1007/S00439-005-0046-4 |
0.47 |
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| 2005 |
Mohlke KL, Boehnke M. The role of HNF4A variants in the risk of type 2 diabetes. Current Diabetes Reports. 5: 149-56. PMID 15794920 DOI: 10.1007/S11892-005-0043-Y |
0.401 |
|
| 2004 |
Conneely KN, Silander K, Scott LJ, Mohlke KL, Lazaridis KN, Valle TT, Tuomilehto J, Bergman RN, Watanabe RM, Buchanan TA, Collins FS, Boehnke M. Variation in the resistin gene is associated with obesity and insulin-related phenotypes in Finnish subjects. Diabetologia. 47: 1782-8. PMID 15517149 DOI: 10.1007/S00125-004-1537-X |
0.466 |
|
| 2004 |
Silander K, Mohlke KL, Scott LJ, Peck EC, Hollstein P, Skol AD, Jackson AU, Deloukas P, Hunt S, Stavrides G, Chines PS, Erdos MR, Narisu N, Conneely KN, Li C, et al. Genetic variation near the hepatocyte nuclear factor-4 alpha gene predicts susceptibility to type 2 diabetes. Diabetes. 53: 1141-9. PMID 15047633 DOI: 10.2337/Diabetes.53.4.1141 |
0.412 |
|
| 2002 |
Mohlke KL, Erdos MR, Scott LJ, Fingerlin TE, Jackson AU, Silander K, Hollstein P, Boehnke M, Collins FS. High-throughput screening for evidence of association by using mass spectrometry genotyping on DNA pools. Proceedings of the National Academy of Sciences of the United States of America. 99: 16928-33. PMID 12482934 DOI: 10.1073/Pnas.262661399 |
0.318 |
|
| 2002 |
Fingerlin TE, Erdos MR, Watanabe RM, Wiles KR, Stringham HM, Mohlke KL, Silander K, Valle TT, Buchanan TA, Tuomilehto J, Bergman RN, Boehnke M, Collins FS. Variation in three single nucleotide polymorphisms in the calpain-10 gene not associated with type 2 diabetes in a large Finnish cohort. Diabetes. 51: 1644-8. PMID 11978669 DOI: 10.2337/Diabetes.51.5.1644 |
0.351 |
|
| 1994 |
Nichols WC, Cooney KA, Mohlke KL, Ballew JD, Yang A, Bruck ME, Reddington M, Novak EK, Swank RT, Ginsburg D. von Willebrand disease in the RIIIS/J mouse is caused by a defect outside of the von Willebrand factor gene. Blood. 83: 3225-31. PMID 8193357 DOI: 10.1182/Blood.V86.6.2461.Bloodjournal8662461 |
0.328 |
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