| Year |
Citation |
Score |
| 2024 |
Ho TC, LaMere MW, Kawano H, Byun DK, LaMere EA, Chiu YC, Chen C, Wang J, Dokholyan NV, Calvi LM, Liesveld JL, Jordan CT, Kapur R, Singh RK, Becker MW. Targeting IL-1/IRAK1/4 signaling in Acute Myeloid Leukemia Stem Cells Following Treatment and Relapse. Biorxiv : the Preprint Server For Biology. PMID 39605740 DOI: 10.1101/2024.11.09.622796 |
0.345 |
|
| 2023 |
Nguyen HP, Le AQ, Liu E, Cesarano A, DiMeo F, Perna F, Kapur R, Walker BA, Tran NT. Protein arginine methyltransferase 1 is a therapeutic vulnerability in multiple myeloma. Frontiers in Immunology. 14: 1239614. PMID 37600810 DOI: 10.3389/fimmu.2023.1239614 |
0.348 |
|
| 2023 |
Palam LR, Ramdas B, Pickerell KM, Pasupuleti SK, Kanumuri R, Cesarano A, Szymanski M, Selman BM, Davé UP, Sandusky G, Perna F, Paczesny S, Kapur R. Loss of Dnmt3a impairs hematopoietic homeostasis and myeloid cell skewing via the PI3Kinase pathway. Jci Insight. PMID 36976647 DOI: 10.1172/jci.insight.163864 |
0.351 |
|
| 2022 |
Wang X, Cooper S, Broxmeyer HE, Kapur R. Transient regulation of RNA methylation in human hematopoietic stem cells promotes their homing and engraftment. Leukemia. PMID 36460765 DOI: 10.1038/s41375-022-01761-4 |
0.304 |
|
| 2022 |
Ramdas B, Yuen LD, Palam LR, Patel R, Pasupuleti SK, Jideonwo V, Zhang J, Maguire C, Wong E, Kanumuri R, Zhang C, Sandusky G, Chan RJ, Zhang C, Stieglitz E, ... ... Kapur R, et al. Inhibition of BTK and PI3Kδ impairs the development of Human JMML Stem and Progenitor cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 35443935 DOI: 10.1016/j.ymthe.2022.04.009 |
0.442 |
|
| 2021 |
Yu H, Gao R, Chen S, Liu X, Wang Q, Cai W, Vemula S, Fahey AC, Henley D, Kobayashi M, Liu SZ, Qian Z, Kapur R, Broxmeyer HE, Gao Z, et al. Bmi1 Regulates Wnt Signaling in Hematopoietic Stem and Progenitor Cells. Stem Cell Reviews and Reports. PMID 34561772 DOI: 10.1007/s12015-021-10253-4 |
0.306 |
|
| 2020 |
Cai Z, Lu X, Zhang C, Nelanuthala S, Aguilera F, Hadley A, Ramdas B, Fang F, Nephew KP, Kotzin JJ, Williams A, Henao-Mejia J, Haneline LS, Kapur R. Hyperglycemia cooperates with Tet2 heterozygosity to induce leukemia driven by pro-inflammatory cytokine induced lncRNA Morrbid. The Journal of Clinical Investigation. PMID 33090974 DOI: 10.1172/JCI140707 |
0.344 |
|
| 2020 |
Burns SS, Kapur R. Clonal Hematopoiesis of Indeterminate Potential as a Novel Risk Factor for Donor-Derived Leukemia. Stem Cell Reports. 15: 279-291. PMID 32783925 DOI: 10.1016/J.Stemcr.2020.07.008 |
0.376 |
|
| 2020 |
Burns SS, Kapur R. Putative Mechanisms Underlying Cardiovascular Disease Associated with Clonal Hematopoiesis of Indeterminate Potential. Stem Cell Reports. PMID 32735822 DOI: 10.1016/J.Stemcr.2020.06.021 |
0.352 |
|
| 2020 |
Cai Z, Zhang C, Kotzin JJ, Williams A, Henao-Mejia J, Kapur R. Role of lncRNA Morrbid in PTPN11(Shp2)E76K-driven juvenile myelomonocytic leukemia. Blood Advances. 4: 3246-3251. PMID 32697817 DOI: 10.1182/Bloodadvances.2020002123 |
0.492 |
|
| 2020 |
Cai Z, Aguilera F, Ramdas B, Daulatabad SV, Srivastava R, Kotzin JJ, Carroll M, Wertheim G, Williams A, Janga SC, Zhang C, Henao-Mejia J, Kapur R. Targeting Bim via a lncRNA Morrbid Regulates the Survival of Preleukemic and Leukemic Cells. Cell Reports. 31: 107816. PMID 32579941 DOI: 10.1016/J.Celrep.2020.107816 |
0.468 |
|
| 2020 |
Ramdas B, Mali RS, Palam LR, Pandey R, Cai Z, Pasupuleti SK, Burns SS, Kapur R. Driver Mutations in Leukemia Promote Disease Pathogenesis through a Combination of Cell-Autonomous and Niche Modulation. Stem Cell Reports. PMID 32502465 DOI: 10.1016/J.Stemcr.2020.05.002 |
0.454 |
|
| 2019 |
Chen S, Wang Q, Yu H, Capitano ML, Vemula S, Nabinger SC, Gao R, Yao C, Kobayashi M, Geng Z, Fahey A, Henley D, Liu SZ, Barajas S, Cai W, ... ... Kapur R, et al. Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway. Nature Communications. 10: 5649. PMID 31827082 DOI: 10.1038/S41467-019-13542-2 |
0.306 |
|
| 2019 |
Pandey R, Ramdas B, Wan C, Sandusky G, Mohseni M, Zhang C, Kapur R. SHP2 inhibition reduces leukemogenesis in models of combined genetic and epigenetic mutations. The Journal of Clinical Investigation. PMID 31682240 DOI: 10.1172/Jci130520 |
0.757 |
|
| 2019 |
Jiang J, Srivastava S, Seim G, Pavlova NN, King B, Zou L, Zhang C, Zhong M, Feng H, Kapur R, Wek RC, Fan J, Zhang J. Promoter demethylation of the asparagine synthetase gene is required for an ATF4-dependent adaptation to asparagine depletion. The Journal of Biological Chemistry. PMID 31659118 DOI: 10.1074/Jbc.Ra119.010447 |
0.397 |
|
| 2019 |
Garg G, Muschaweckh A, Moreno H, Vasanthakumar A, Floess S, Lepennetier G, Oellinger R, Zhan Y, Regen T, Hiltensperger M, Peter C, Aly L, Knier B, Palam LR, Kapur R, et al. Blimp1 Prevents Methylation of Foxp3 and Loss of Regulatory T Cell Identity at Sites of Inflammation. Cell Reports. 26: 1854-1868.e5. PMID 30759395 DOI: 10.1016/J.Celrep.2019.01.070 |
0.446 |
|
| 2019 |
Nabinger SC, Chen S, Gao R, Yao C, Kobayashi M, Vemula S, Fahey AC, Wang C, Daniels C, Boswell HS, Sandusky GE, Mayo LD, Kapur R, Liu Y. Mutant p53 enhances leukemia-initiating cell self-renewal to promote leukemia development. Leukemia. PMID 30675010 DOI: 10.1038/S41375-019-0377-0 |
0.398 |
|
| 2019 |
Ramdas B, Palam LR, Mali RS, Cai Z, Pandey R, Kapur R. Combined Heterozygous Loss of Tet2 and Dnmt3a Along with Expression of Flt3ITD/WT results in Acute Myeloid Leukemia Which Responds to a Combination of FLT3 Inhibitor, APE1 Inhibitor and Decitabine Blood. 134: 3754-3754. DOI: 10.1182/Blood-2019-131172 |
0.449 |
|
| 2019 |
Palam LR, Ramdas B, Pickerell K, Kapur R. Loss of Dnmt3a Dysregulates Hematopoietic Homeostasis and Myeloid Skewing Via the PI3Kinase Pathway: PI3Kα/β Inhibition Corrects Extramedullary Hematopoiesis and Myeloid Skewing Due to Loss of Dnmt3a Blood. 134: 723-723. DOI: 10.1182/Blood-2019-131036 |
0.511 |
|
| 2019 |
Cai Z, Ramdas B, Kotzin J, Carroll MP, Wertheim G, Williams A, Henao-Mejia J, Kapur R. Lncrna Morrbid Regulates Myeloid Cell Survival of AML Driven By a Combination of FLT3ITD and Epigenetic Mutations Blood. 134: 915-915. DOI: 10.1182/Blood-2019-130653 |
0.502 |
|
| 2019 |
Rangaraju S, Marino S, Roodman GD, Cripe LD, Ramdas B, Palam LR, Sargent KJ, Sayar H, Konig H, Kapur R, Boswell HS. Cooperativity between Flt3/Syk and Proteasome Inhibitors in Flt3mutant/Wildtype AML, By Acting on the Oxphos and Wnt Endpoints of Syk and p62SQSTM1 Pathways Prohibits Protective Autophagy; While Downregulation of NRF2, NQO1, Jun, and b-Catenin Bypasses Interfering RAS or WT1 Co-Mutations Blood. 134: 5051-5051. DOI: 10.1182/Blood-2019-124384 |
0.431 |
|
| 2018 |
Prudent R, Demoncheaux N, Diemer H, Collin-Faure V, Kapur R, Paublant F, Lafanechère L, Cianférani S, Rabilloud T. A quantitative proteomic analysis of cofilin phosphorylation in myeloid cells and its modulation using the LIM kinase inhibitor Pyr1. Plos One. 13: e0208979. PMID 30550596 DOI: 10.1371/Journal.Pone.0208979 |
0.393 |
|
| 2018 |
Cai Z, Kotzin JJ, Ramdas B, Chen S, Nelanuthala S, Palam LR, Pandey R, Mali RS, Liu Y, Kelley MR, Sandusky G, Mohseni M, Williams A, Henao-Mejia J, Kapur R. Inhibition of Inflammatory Signaling in Tet2 Mutant Preleukemic Cells Mitigates Stress-Induced Abnormalities and Clonal Hematopoiesis. Cell Stem Cell. 23: 833-849.e5. PMID 30526882 DOI: 10.1016/J.Stem.2018.10.013 |
0.754 |
|
| 2018 |
Hu P, Nebreda AR, Hanenberg H, Kinnebrew GH, Ivan M, Yoder MC, Filippi MD, Broxmeyer HE, Kapur R. P38α/JNK signaling restrains erythropoiesis by suppressing Ezh2-mediated epigenetic silencing of Bim. Nature Communications. 9: 3518. PMID 30158520 DOI: 10.1038/s41467-018-05955-2 |
0.405 |
|
| 2018 |
Palam LR, Mali RS, Ramdas B, Srivatsan SN, Visconte V, Tiu RV, Vanhaesebroeck B, Roers A, Gerbaulet A, Xu M, Janga SC, Takemoto CM, Paczesny S, Kapur R. Loss of epigenetic regulator TET2 and oncogenic KIT regulate myeloid cell transformation via PI3K pathway. Jci Insight. 3. PMID 29467326 DOI: 10.1172/Jci.Insight.94679 |
0.518 |
|
| 2018 |
Deng L, Richine BM, Virts EL, Jideonwo-Auman VN, Chan RJ, Kapur R. Rapid development of myeloproliferative neoplasm in mice withmutation and haploinsufficient for. Oncotarget. 9: 6055-6061. PMID 29464054 DOI: 10.18632/Oncotarget.23680 |
0.428 |
|
| 2018 |
Sayar H, Liu Y, Gao R, Zaid MA, Cripe LD, Weisenbach J, Sargent KJ, Nassiri M, Li L, Konig H, Suvannasankha A, Pan F, Shanmugam R, Goswami C, Kapur R, et al. Consecutive epigenetically-active agent combinations act inandpathways forAML. Oncotarget. 9: 5703-5715. PMID 29464028 DOI: 10.18632/Oncotarget.23655 |
0.351 |
|
| 2018 |
Patel R, Ramdas B, Deng L, Jideonwo-Auman V, Kapur R. Combined inhibition of Bruton’s Tyrosine Kinase (BTK) and Phosphoinositide 3-kinase (PI3K) p110δ improves monocytosis and splenomegaly in a JMML Mouse Model Proceedings of Imprs. 1. DOI: 10.18060/22825 |
0.311 |
|
| 2018 |
Patel R, Ramdas B, Deng L, Jideonwo-Auman V, Chan RJ, Kapur R. Combined Pharmacological Inhibition of Bruton's Tyrosine Kinase (BTK) and Phosphoinositide 3-Kinase (PI3K) p110δ Rescues Monocytosis, Thrombocytopenia, and Splenomegaly in a Genetic Mouse Model for JMML Blood. 132: 2623-2623. DOI: 10.1182/Blood-2018-99-118802 |
0.56 |
|
| 2018 |
Palam LR, Ramdas B, Srivatsan Sr, Janga SC, Roers A, Gerbaulet A, Kapur R. Temporal and Spatially Regulated Oncogenic KIT Expression and Loss of Dnmt3a Cooperate to Drive MPN Development: Role of PI3Kinase in Dnmt3a Loss Induced Hyperproliferation in Myeloid Cells Blood. 132: 3055-3055. DOI: 10.1182/Blood-2018-99-118721 |
0.548 |
|
| 2018 |
Ramdas B, Ghosh J, Mali RS, Amy Z, Carlesso N, Kamocka M M, Kenneth DW, Quilliam L, Kapur R. Rap1 Gtpases Regulate the Retention and Engraftment of Hematopoietic Stem and Progenitor Cells Blood. 132: 326-326. DOI: 10.1182/Blood-2018-99-117197 |
0.468 |
|
| 2018 |
Cai Z, Kotzin J, Ramdas B, Chen S, Nelanuthala S, Palam LR, Pandey R, Mali R, Liu Y, Kelley MR, Sandusky G, Mohseni M, Williams A, Henao-Mejia J, Kapur R. Downregulation of Morrbid in Tet2-Deficient Preleukemic Cells Overcomes Resistance to Inflammatory Stress and Mitigates Clonal Hematopoiesis Blood. 132: 1288-1288. DOI: 10.1182/Blood-2018-99-116703 |
0.763 |
|
| 2018 |
Rangaraju S, Marino S, Petrusca DN, Cripe LD, Sargent KJ, Roodman GD, Sayar H, Ramdas B, Palam LR, Shanmugam R, Rogozea A, Konig H, Kapur R, Boswell HS. Identification of Beta-Catenin As a Novel Ubiquitin-Regulated Target of Combined Flβ3/Syk- and Proteasome Inhibitors for Interruption of LSC Signaling in Poor-Risk AML Blood. 132: 3949-3949. DOI: 10.1182/Blood-2018-99-111181 |
0.395 |
|
| 2017 |
Chen S, Gao R, Yao C, Kobayashi M, Liu SZ, Yoder MC, Broxmeyer H, Kapur R, Boswell HS, Mayo LD, Liu Y. Genotoxic stresses promote clonal expansion of hematopoietic stem cells expressing mutant p53. Leukemia. PMID 29263439 DOI: 10.1038/Leu.2017.325 |
0.409 |
|
| 2017 |
Deng L, Virts EL, Kapur R, Chan RJ. Pharmacologic inhibition of PI3K p110δ in mutant Shp2E76K-expressing mice. Oncotarget. 8: 84776-84781. PMID 29156682 DOI: 10.18632/Oncotarget.21455 |
0.468 |
|
| 2017 |
Ramadan A, Griesenauer B, Adom D, Kapur R, Hanenberg H, Liu C, Kaplan MH, Paczesny S. Specifically differentiated T cell subset promotes tumor immunity over fatal immunity. The Journal of Experimental Medicine. PMID 29038366 DOI: 10.1084/Jem.20170041 |
0.408 |
|
| 2017 |
Metts J, Bradley HL, Wang Z, Shah NP, Kapur R, Arbiser JL, Bunting KD. Imipramine blue sensitively and selectively targets FLT3-ITD positive acute myeloid leukemia cells. Scientific Reports. 7: 4447. PMID 28667329 DOI: 10.1038/S41598-017-04796-1 |
0.369 |
|
| 2017 |
Prunier C, Prudent R, Kapur R, Sadoul K, Lafanechère L. LIM kinases: cofilin and beyond. Oncotarget. PMID 28445157 DOI: 10.18632/Oncotarget.16978 |
0.357 |
|
| 2017 |
O'Leary HA, Capitano M, Cooper S, Mantel C, Boswell HS, Kapur R, Ramdas B, Chan R, Deng L, Qu CK, Broxmeyer HE. DPP4 truncated GM-CSF & IL-3 manifest distinct receptor binding & regulatory functions compared to their full length forms. Leukemia. PMID 28344320 DOI: 10.1038/Leu.2017.98 |
0.378 |
|
| 2017 |
Ghosh J, Kapur R. Role of mTORC1-S6K1 signaling pathway in regulation of hematopoietic stem cell and acute myeloid leukemia. Experimental Hematology. PMID 28342808 DOI: 10.1016/J.Exphem.2017.02.004 |
0.459 |
|
| 2017 |
Pandey R, Saxena M, Kapur R. Role of SHP2 in hematopoiesis and leukemogenesis. Current Opinion in Hematology. PMID 28306669 DOI: 10.1097/Moh.0000000000000345 |
0.407 |
|
| 2017 |
Kobayashi M, Chen S, Bai Y, Yao C, Gao R, Sun XJ, Mu C, Twiggs TA, Yu ZH, Boswell HS, Yoder MC, Kapur R, Mulloy JC, Zhang ZY, Liu Y. Phosphatase PRL2 promotes AML1-ETO-induced acute myeloid leukemia. Leukemia. PMID 28220038 DOI: 10.1038/Leu.2017.67 |
0.312 |
|
| 2017 |
Hinge A, Xu J, Javier J, Mose E, Kumar S, Kapur R, Srour EF, Malik P, Aronow BJ, Filippi MD. p190-B RhoGAP and intracellular cytokine signals balance hematopoietic stem and progenitor cell self-renewal and differentiation. Nature Communications. 8: 14382. PMID 28176763 DOI: 10.1038/Ncomms14382 |
0.384 |
|
| 2016 |
Kobayashi M, Nabinger S, Bai Y, Yoshimoto M, Gao R, Chen S, Yao C, Dong Y, Zhang L, Rodriguez S, Yashiro-Ohtani Y, Pear WS, Carlesso N, Yoder MC, Kapur R, et al. Protein Tyrosine Phosphatase PRL2 Mediates Notch and Kit Signals In Early T Cell Progenitors. Stem Cells (Dayton, Ohio). PMID 28009085 DOI: 10.1002/Stem.2559 |
0.475 |
|
| 2016 |
Chen S, Gao R, Kobayashi M, Yu H, Yao C, Kapur R, Yoder MC, Liu Y. Pharmacological inhibition of AKT activity in human CD34(+) cells enhances their ability to engraft immunodeficient mice. Experimental Hematology. PMID 27645691 DOI: 10.1016/J.Exphem.2016.09.003 |
0.41 |
|
| 2016 |
Ghosh J, Kobayashi M, Ramdas B, Chatterjee A, Ma P, Mali RS, Carlesso N, Liu Y, Plas DR, Chan RJ, Kapur R. S6K1 regulates hematopoietic stem cell self-renewal and leukemia maintenance. The Journal of Clinical Investigation. PMID 27294524 DOI: 10.1172/Jci84565 |
0.481 |
|
| 2016 |
Zhang H, Rodriguez S, Wang L, Wang S, Serezani H, Kapur R, Cardoso AA, Carlesso N. Sepsis Induces Hematopoietic Stem Cell Exhaustion and Myelosuppression through Distinct Contributions of TRIF and MYD88. Stem Cell Reports. PMID 27264973 DOI: 10.1016/J.Stemcr.2016.05.002 |
0.49 |
|
| 2016 |
Richine BM, Virts EL, Bowling JD, Ramdas B, Mali R, Naoye R, Liu Z, Zhang ZY, Boswell HS, Kapur R, Chan RJ. Syk kinase and Shp2 phosphatase inhibition cooperate to reduce FLT3-ITD-induced STAT5 activation and proliferation of acute myeloid leukemia. Leukemia. PMID 27256702 DOI: 10.1038/Leu.2016.131 |
0.414 |
|
| 2016 |
Prunier C, Josserand V, Vollaire J, Beerling E, Petropoulos C, Destaing O, Montemagno C, Hurbin A, Prudent R, de Koning L, Kapur R, Cohen PA, Albiges-Rizo C, Coll JL, van Rheenen J, et al. LIM kinase inhibitor Pyr1 reduces the growth and metastatic load of breast cancers. Cancer Research. PMID 27216191 DOI: 10.1158/0008-5472.Can-15-1864 |
0.354 |
|
| 2016 |
Li XJ, Deng L, Brandt SL, Goodwin CB, Ma P, Yang Z, Mali RS, Liu Z, Kapur R, Serezani CH, Chan RJ. Role of p85α in neutrophil extra- and intracellular reactive oxygen species generation. Oncotarget. PMID 27049833 DOI: 10.18632/Oncotarget.8500 |
0.33 |
|
| 2016 |
Kapur R, Shi J, Ghosh J, Munugalavadla V, Sims E, Martin H, Wei L, Mali RS. ROCK1 via LIM kinase regulates growth, maturation and actin based functions in mast cells. Oncotarget. PMID 26943578 DOI: 10.18632/Oncotarget.7851 |
0.503 |
|
| 2016 |
Bessler WK, Kim G, Hudson F, Mund JA, Mali R, Menon K, Kapur R, Clapp DW, Ingram DA, Stansfield BK. Nf1+/- Monocytes/Macrophages Induce Neointima Formation via CCR2 Activation. Human Molecular Genetics. PMID 26740548 DOI: 10.1093/Hmg/Ddv635 |
0.354 |
|
| 2016 |
Ma P, Sun Y, Wang J, Song W, Xu T, Kapur R, Hess JL. The Role of STAT5 in HOXA9-Associated Leukemia Blood. 128: 3919-3919. DOI: 10.1182/Blood.V128.22.3919.3919 |
0.507 |
|
| 2016 |
Ramadan A, Zhang J, Zaid MA, Taylor L, O'Leary H, Kapur R, Hanenberg H, Broxmeyer H, Kaplan M, Paczesny S. Id: 95: Il-33/St2 Triggering Of Il-9–Secreting T Cells: From Proteomics To Therapeutics Journal of Investigative Medicine. 64: 948-948. DOI: 10.1136/Jim-2016-000120.73 |
0.442 |
|
| 2016 |
Zhang J, Ramadan A, Griesenauer B, Li W, Turner M, Kapur R, Hanenberg H, Paczesny S, Liu C, Blazar B, Tawara I. Id: 91: St2 Blockade Reduces Sst2-Producing T Cells While Maintaining Protective Mst2-Expressing T Cells During Graft-Versus-Host Disease Journal of Investigative Medicine. 64: 946-947. DOI: 10.1136/Jim-2016-000120.69 |
0.423 |
|
| 2016 |
Ramadan A, Zhang J, Zaid MA, Taylor L, O'Leary HA, Kapur R, Hanenberg H, Broxmeyer HE, Kaplan MH, Paczesny S. 508. IL-33/ST2 Triggering of IL-9-Secreting T Cells: From Proteomics to Therapeutics Molecular Therapy. 24: S202-S203. DOI: 10.1016/S1525-0016(16)33317-2 |
0.443 |
|
| 2016 |
Ghosh J, Kapur R. Regulation of Hematopoietic Stem Cell Self-Renewal and Leukemia Maintenance by the PI3K-mTORC1 Pathway Current Stem Cell Reports. 2: 368-378. DOI: 10.1007/S40778-016-0067-Z |
0.441 |
|
| 2015 |
Onishi C, Mori-Kimachi S, Hirade T, Abe M, Taketani T, Suzumiya J, Sugimoto T, Yamaguchi S, Kapur R, Fukuda S. Internal tandem duplication mutations in FLT3 gene augment chemotaxis to Cxcl12 protein by blocking the down-regulation of Rho-associated kinase via the Cxcl12/Cxcr4 signaling axis. The Journal of Biological Chemistry. 290: 28356. PMID 26590297 DOI: 10.1074/Jbc.A114.568287 |
0.398 |
|
| 2015 |
Zhang J, Ramadan AM, Griesenauer B, Li W, Turner MJ, Liu C, Kapur R, Hanenberg H, Blazar BR, Tawara I, Paczesny S. ST2 blockade reduces sST2-producing T cells while maintaining protective mST2-expressing T cells during graft-versus-host disease. Science Translational Medicine. 7: 308ra160. PMID 26446957 DOI: 10.1126/Scitranslmed.Aab0166 |
0.389 |
|
| 2015 |
Chatterjee A, Ghosh J, Kapur R. Mastocytosis: a mutated KIT receptor induced myeloproliferative disorder. Oncotarget. 6: 18250-64. PMID 26158763 DOI: 10.18632/Oncotarget.4213 |
0.345 |
|
| 2015 |
Mantel CR, O'Leary HA, Chitteti BR, Huang X, Cooper S, Hangoc G, Brustovetsky N, Srour EF, Lee MR, Messina-Graham S, Haas DM, Falah N, Kapur R, Pelus LM, Bardeesy N, et al. Enhancing Hematopoietic Stem Cell Transplantation Efficacy by Mitigating Oxygen Shock. Cell. 161: 1553-65. PMID 26073944 DOI: 10.1016/J.Cell.2015.04.054 |
0.357 |
|
| 2015 |
Pandey R, Kapur R. Targeting phosphatidylinositol-3-kinase pathway for the treatment of Philadelphia-negative myeloproliferative neoplasms. Molecular Cancer. 14: 118. PMID 26062813 DOI: 10.1186/S12943-015-0388-Z |
0.439 |
|
| 2015 |
Gao R, Chen S, Kobayashi M, Yu H, Zhang Y, Wan Y, Young SK, Soltis A, Yu M, Vemula S, Fraenkel E, Cantor A, Antipin Y, Xu Y, Yoder MC, ... ... Kapur R, et al. Bmi1 promotes erythroid development through regulating ribosome biogenesis. Stem Cells (Dayton, Ohio). 33: 925-38. PMID 25385494 DOI: 10.1002/Stem.1896 |
0.45 |
|
| 2015 |
Mali R, Martin HR, Ramdas B, Palam L, Visconte V, Ramon T, Hanenberg H, Xu M, Kapur R. Novel Functional Roles for Ten-Eleven-Translocation 2 (Tet2) in Normal and Leukemic Growth of Mast Cells Blood. 126: 775-775. DOI: 10.1182/Blood.V126.23.775.775 |
0.534 |
|
| 2015 |
Ghosh J, Chatterjee A, Ramdas B, Kobayashi M, Ma P, Liu Y, Plas D, Kapur R. S6K1 Regulates Self-Renewal of Leukemia Initiating Cells and Normal Hematopoietic Stem Cells Blood. 126: 442-442. DOI: 10.1182/Blood.V126.23.442.442 |
0.527 |
|
| 2015 |
Metts JL, Bradley HL, Shah NP, Kapur R, Arbiser JL, Bunting KD. Imipramine Blue Sensitively and Selectively Targets FLT3 and c-Kit Mutant Acute Myeloid Leukemia Blood. 126: 3688-3688. DOI: 10.1182/Blood.V126.23.3688.3688 |
0.489 |
|
| 2015 |
Ramadan A, Zhang J, Abu Zaid M, O'Leary H, Kapur R, Hanenberg H, Sun J, Broxmeyer HE, Kaplan MH, Paczesny S. IL-33/ST2 Triggering of IL-9-Secreting T Cells Alters the Balance of Fatal Immunity and Tumor Immunity Blood. 126: 231-231. DOI: 10.1182/Blood.V126.23.231.231 |
0.423 |
|
| 2015 |
Pandey R, Mali R, Ramdas B, Kapur R. Novel Mechanisms of Growth Inhibition By Histone Deacetylase Inhibitors in MPN Blood. 126: 1633-1633. DOI: 10.1182/Blood.V126.23.1633.1633 |
0.524 |
|
| 2015 |
Pandey R, Mali R, Chatterjee A, Paublant F, Prudent R, Lafanechere L, Kapur R. Role of LIM Kinase in Oncogenic Signaling from FLT3 and KIT Receptors and Its Targeting in Myeloid Leukemia Blood. 126: 1257-1257. DOI: 10.1182/Blood.V126.23.1257.1257 |
0.539 |
|
| 2014 |
Chatterjee A, Ghosh J, Ramdas B, Mali RS, Martin H, Kobayashi M, Vemula S, Canela VH, Waskow ER, Visconte V, Tiu RV, Smith CC, Shah N, Bunting KD, Boswell HS, ... ... Kapur R, et al. Regulation of Stat5 by FAK and PAK1 in Oncogenic FLT3- and KIT-Driven Leukemogenesis. Cell Reports. 9: 1333-48. PMID 25456130 DOI: 10.1016/J.Celrep.2014.10.039 |
0.482 |
|
| 2014 |
Onish C, Mori-Kimachi S, Hirade T, Abe M, Taketani T, Suzumiya J, Sugimoto T, Yamaguchi S, Kapur R, Fukuda S. Internal tandem duplication mutations in FLT3 gene augment chemotaxis to Cxcl12 protein by blocking the down-regulation of the Rho-associated kinase via the Cxcl12/Cxcr4 signaling axis. The Journal of Biological Chemistry. 289: 31053-65. PMID 25237195 DOI: 10.1074/Jbc.M114.568287 |
0.519 |
|
| 2014 |
Oh SY, Brandal S, Kapur R, Zhu Z, Takemoto CM. Global microRNA expression is essential for murine mast cell development in vivo. Experimental Hematology. 42: 919-23.e1. PMID 25201754 DOI: 10.1016/J.Exphem.2014.07.266 |
0.378 |
|
| 2014 |
Kumar S, Xu J, Kumar RS, Lakshmikanthan S, Kapur R, Kofron M, Chrzanowska-Wodnicka M, Filippi MD. The small GTPase Rap1b negatively regulates neutrophil chemotaxis and transcellular diapedesis by inhibiting Akt activation. The Journal of Experimental Medicine. 211: 1741-58. PMID 25092872 DOI: 10.1084/Jem.20131706 |
0.406 |
|
| 2014 |
Kobayashi M, Shelley WC, Seo W, Vemula S, Lin Y, Liu Y, Kapur R, Taniuchi I, Yoshimoto M. Functional B-1 progenitor cells are present in the hematopoietic stem cell-deficient embryo and depend on Cbfβ for their development. Proceedings of the National Academy of Sciences of the United States of America. 111: 12151-6. PMID 25092306 DOI: 10.1073/Pnas.1407370111 |
0.363 |
|
| 2014 |
Sharma N, Everingham S, Zeng LF, Zhang ZY, Kapur R, Craig AW. Oncogenic KIT-induced aggressive systemic mastocytosis requires SHP2/PTPN11 phosphatase for disease progression in mice. Oncotarget. 5: 6130-41. PMID 25026279 DOI: 10.18632/Oncotarget.2177 |
0.529 |
|
| 2014 |
Zeng LF, Zhang RY, Yu ZH, Li S, Wu L, Gunawan AM, Lane BS, Mali RS, Li X, Chan RJ, Kapur R, Wells CD, Zhang ZY. Therapeutic potential of targeting the oncogenic SHP2 phosphatase. Journal of Medicinal Chemistry. 57: 6594-609. PMID 25003231 DOI: 10.1021/Jm5006176 |
0.339 |
|
| 2014 |
Mali RS, Kapur S, Kapur R. Role of Rho kinases in abnormal and normal hematopoiesis. Current Opinion in Hematology. 21: 271-5. PMID 24867289 DOI: 10.1097/Moh.0000000000000056 |
0.409 |
|
| 2014 |
Kobayashi M, Bai Y, Dong Y, Yu H, Chen S, Gao R, Zhang L, Yoder MC, Kapur R, Zhang ZY, Liu Y. PRL2/PTP4A2 phosphatase is important for hematopoietic stem cell self-renewal. Stem Cells (Dayton, Ohio). 32: 1956-67. PMID 24753135 DOI: 10.1002/Stem.1672 |
0.495 |
|
| 2014 |
Sharma N, Everingham S, Ramdas B, Kapur R, Craig AW. SHP2 phosphatase promotes mast cell chemotaxis toward stem cell factor via enhancing activation of the Lyn/Vav/Rac signaling axis. Journal of Immunology (Baltimore, Md. : 1950). 192: 4859-66. PMID 24733849 DOI: 10.4049/Jimmunol.1301155 |
0.547 |
|
| 2014 |
Surma M, Handy C, Chang J, Kapur R, Wei L, Shi J. ROCK1 deficiency enhances protective effects of antioxidants against apoptosis and cell detachment. Plos One. 9: e90758. PMID 24595357 DOI: 10.1371/Journal.Pone.0090758 |
0.372 |
|
| 2014 |
Goodwin CB, Li XJ, Mali RS, Chan G, Kang M, Liu Z, Vanhaesebroeck B, Neel BG, Loh ML, Lannutti BJ, Kapur R, Chan RJ. PI3K p110δ uniquely promotes gain-of-function Shp2-induced GM-CSF hypersensitivity in a model of JMML. Blood. 123: 2838-42. PMID 24553178 DOI: 10.1182/Blood-2013-10-535104 |
0.477 |
|
| 2014 |
Stansfield BK, Bessler WK, Mali R, Mund JA, Downing BD, Kapur R, Ingram DA. Ras-Mek-Erk signaling regulates Nf1 heterozygous neointima formation. The American Journal of Pathology. 184: 79-85. PMID 24211110 DOI: 10.1016/J.Ajpath.2013.09.022 |
0.404 |
|
| 2014 |
Mantel C, O'Leary HA, Chitteti BR, Huang X, Cooper S, Hangoc G, Brustovetsky N, Srour EF, Lee MR, Messina-Graham S, Falah N, Kapur R, Pelus LM, Ivan M, Kim K, et al. Mitigation of a Newly Discovered Phenomenon, Extra Physiologic Oxygen Shock/Stress (EPHOSS), Mediated By the Mitochondria Permeability Transition Pore, Greatly Improves Stem Cell Collection and Transplantation Blood. 124: 2905-2905. DOI: 10.1182/Blood.V124.21.2905.2905 |
0.383 |
|
| 2014 |
Ghosh J, Ramdas B, Chatterjee A, Ma P, Kobayashi M, Mali R, Liu Y, Plas D, Kapur R. Modulation in the expression of p70S6 kinase impairs the engraftment and self-renewal of hematopoietic stem cells Experimental Hematology. 42: S35. DOI: 10.1182/Blood.V124.21.252.252 |
0.501 |
|
| 2014 |
Ghosh J, Ramdas B, Chatterjee A, Ma P, Kobayashi M, Mali R, Liu Y, Plas DR, Kapur R. Modulation in the Expression of p70S6 Kinase Impairs the Engraftment and Self-Renewal of Hematopoietic Stem Cells Blood. 124: 252-252. DOI: 10.1182/blood.v124.21.252.252 |
0.406 |
|
| 2013 |
Martin H, Mali RS, Ma P, Chatterjee A, Ramdas B, Sims E, Munugalavadla V, Ghosh J, Mattingly RR, Visconte V, Tiu RV, Vlaar CP, Dharmawardhane S, Kapur R. Pak and Rac GTPases promote oncogenic KIT-induced neoplasms. The Journal of Clinical Investigation. 123: 4449-63. PMID 24091327 DOI: 10.1172/Jci67509 |
0.495 |
|
| 2013 |
Shi J, Wu X, Surma M, Vemula S, Zhang L, Yang Y, Kapur R, Wei L. Distinct roles for ROCK1 and ROCK2 in the regulation of cell detachment. Cell Death & Disease. 4: e483. PMID 23392171 DOI: 10.1038/Cddis.2013.10 |
0.385 |
|
| 2013 |
Mali RS, Kapur R. Unique and redundant roles of class IA PI3Kinase regulatory subunits in mast cell development. Cell Cycle (Georgetown, Tex.). 12: 7-8. PMID 23255115 DOI: 10.4161/Cc.23070 |
0.552 |
|
| 2013 |
Stansfield BK, Bessler WK, Mali R, Mund JA, Downing B, Li F, Sarchet KN, DiStasi MR, Conway SJ, Kapur R, Ingram DA. Heterozygous inactivation of the Nf1 gene in myeloid cells enhances neointima formation via a rosuvastatin-sensitive cellular pathway. Human Molecular Genetics. 22: 977-88. PMID 23197650 DOI: 10.1093/Hmg/Dds502 |
0.382 |
|
| 2013 |
Nabinger SC, Li XJ, Ramdas B, He Y, Zhang X, Zeng L, Richine B, Bowling JD, Fukuda S, Goenka S, Liu Z, Feng GS, Yu M, Sandusky GE, Boswell HS, ... ... Kapur R, et al. The protein tyrosine phosphatase, Shp2, positively contributes to FLT3-ITD-induced hematopoietic progenitor hyperproliferation and malignant disease in vivo. Leukemia. 27: 398-408. PMID 23103841 DOI: 10.1038/leu.2012.308 |
0.406 |
|
| 2013 |
Gao R, Chen S, Kobayashi M, Yoder MC, Kapur R, Zhu X, Liu Y. BMI1 Promotes Erythropoiesis Through Regulating Ribosome Biogenesis Blood. 122: 3707-3707. DOI: 10.1182/Blood.V122.21.3707.3707 |
0.478 |
|
| 2013 |
Goodwin CB, Mali R, Chan G, Neel B, Lannutti B, Kapur R, Chan RJ. Phosphatidylinositol-3-Kinase p110d Uniquely Promotes Gain-Of-Function PTPN11-Induced GM-CSF Hypersensitivity In a Model Of Juvenile Myelomonocytic Leukemia Blood. 122: 3678-3678. DOI: 10.1182/Blood.V122.21.3678.3678 |
0.419 |
|
| 2013 |
Kobayashi M, Dong Y, Yu H, Bai Y, Chen S, Gao R, Yoder MC, Kapur R, Zhang Z, Liu Y. PRL2 Maintains Hematopoietic Stem and Progenitor Cells Through Regulating SCF/KIT Signaling Blood. 122: 3674-3674. DOI: 10.1182/Blood.V122.21.3674.3674 |
0.504 |
|
| 2013 |
Wang L, Zhang H, Rodriguez-Rodriguez S, Cao L, Parish J, Zollman A, Kamocka M, Boswell HS, Srour EF, Chitteti BR, Manshouri T, Verstovsek S, Kapur R, Cardoso AA, Carlesso N. Loss Of Canonic Notch Signaling In The Microenvironment Causes a Myeloproliferative Syndrome Via Derepression Of The miR155 Promoter Blood. 122: 339-339. DOI: 10.1182/Blood.V122.21.339.339 |
0.385 |
|
| 2012 |
Mali RS, Chan R, Kapur R. Targeting SHP2 phosphatase in myeloproliferative neoplasms. Oncotarget. 3: 1049-51. PMID 23165317 DOI: 10.18632/Oncotarget.665 |
0.551 |
|
| 2012 |
Traina F, Visconte V, Jankowska AM, Makishima H, O'Keefe CL, Elson P, Han Y, Hsieh FH, Sekeres MA, Mali RS, Kalaycio M, Lichtin AE, Advani AS, Duong HK, Copelan E, ... Kapur R, et al. Single nucleotide polymorphism array lesions, TET2, DNMT3A, ASXL1 and CBL mutations are present in systemic mastocytosis. Plos One. 7: e43090. PMID 22905207 DOI: 10.1371/Journal.Pone.0043090 |
0.305 |
|
| 2012 |
Vemula S, Shi J, Mali RS, Ma P, Liu Y, Hanneman P, Koehler KR, Hashino E, Wei L, Kapur R. ROCK1 functions as a critical regulator of stress erythropoiesis and survival by regulating p53. Blood. 120: 2868-78. PMID 22889758 DOI: 10.1182/Blood-2011-10-384172 |
0.427 |
|
| 2012 |
Wen Q, Goldenson B, Silver SJ, Schenone M, Dancik V, Huang Z, Wang LZ, Lewis TA, An WF, Li X, Bray MA, Thiollier C, Diebold L, Gilles L, Vokes MS, ... ... Kapur R, et al. Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL. Cell. 150: 575-89. PMID 22863010 DOI: 10.1016/J.Cell.2012.06.032 |
0.334 |
|
| 2012 |
Hu P, Nebreda AR, Liu Y, Carlesso N, Kaplan M, Kapur R. p38α protein negatively regulates T helper type 2 responses by orchestrating multiple T cell receptor-associated signals. The Journal of Biological Chemistry. 287: 33215-26. PMID 22859305 DOI: 10.1074/Jbc.M112.355594 |
0.43 |
|
| 2012 |
Mali RS, Ma P, Zeng LF, Martin H, Ramdas B, He Y, Sims E, Nabinger S, Ghosh J, Sharma N, Munugalavadla V, Chatterjee A, Li S, Sandusky G, Craig AW, ... ... Kapur R, et al. Role of SHP2 phosphatase in KIT-induced transformation: identification of SHP2 as a druggable target in diseases involving oncogenic KIT. Blood. 120: 2669-78. PMID 22806893 DOI: 10.1182/Blood-2011-08-375873 |
0.457 |
|
| 2012 |
Gallo RM, Khan MA, Shi J, Kapur R, Wei L, Bailey JC, Liu J, Brutkiewicz RR. Regulation of the actin cytoskeleton by Rho kinase controls antigen presentation by CD1d. Journal of Immunology (Baltimore, Md. : 1950). 189: 1689-98. PMID 22798677 DOI: 10.4049/Jimmunol.1101484 |
0.417 |
|
| 2012 |
Sharma N, Kumar V, Everingham S, Mali RS, Kapur R, Zeng LF, Zhang ZY, Feng GS, Hartmann K, Roers A, Craig AW. SH2 domain-containing phosphatase 2 is a critical regulator of connective tissue mast cell survival and homeostasis in mice. Molecular and Cellular Biology. 32: 2653-63. PMID 22566685 DOI: 10.1128/Mcb.00308-12 |
0.529 |
|
| 2012 |
Hu P, Carlesso N, Xu M, Liu Y, Nebreda AR, Takemoto C, Kapur R. Genetic evidence for critical roles of P38α protein in regulating mast cell differentiation and chemotaxis through distinct mechanisms. The Journal of Biological Chemistry. 287: 20258-69. PMID 22518842 DOI: 10.1074/Jbc.M112.358119 |
0.53 |
|
| 2012 |
Ruschmann J, Antignano F, Lam V, Snyder K, Kim C, Essak M, Zhang A, Lin AH, Mali RS, Kapur R, Krystal G. The role of SHIP in the development and activation of mouse mucosal and connective tissue mast cells. Journal of Immunology (Baltimore, Md. : 1950). 188: 3839-50. PMID 22430739 DOI: 10.4049/Jimmunol.1003875 |
0.405 |
|
| 2012 |
Krishnan S, Mali RS, Ramdas B, Sims E, Ma P, Ghosh J, Munugalavadla V, Hanneman P, Beane JD, Kapur R. p85β regulatory subunit of class IA PI3 kinase negatively regulates mast cell growth, maturation, and leukemogenesis. Blood. 119: 3951-61. PMID 22378847 DOI: 10.1182/Blood-2011-05-355602 |
0.687 |
|
| 2012 |
Ma P, Mali RS, Martin H, Ramdas B, Sims E, Kapur R. Role of intracellular tyrosines in activating KIT-induced myeloproliferative disease. Leukemia. 26: 1499-506. PMID 22297723 DOI: 10.1038/Leu.2012.22 |
0.462 |
|
| 2012 |
Krishnan S, Mali RS, Koehler KR, Vemula S, Chatterjee A, Ghosh J, Ramdas B, Ma P, Hashino E, Kapur R. Class I(A) PI3Kinase regulatory subunit, p85α, mediates mast cell development through regulation of growth and survival related genes. Plos One. 7: e28979. PMID 22238586 DOI: 10.1371/Journal.Pone.0028979 |
0.714 |
|
| 2012 |
Wu L, Yan C, Czader M, Foreman O, Blum JS, Kapur R, Du H. Inhibition of PPARγ in myeloid-lineage cells induces systemic inflammation, immunosuppression, and tumorigenesis. Blood. 119: 115-26. PMID 22053106 DOI: 10.1182/Blood-2011-06-363093 |
0.474 |
|
| 2012 |
Goodwin CB, Gearinger RL, Mali R, Cerabona D, Chan G, Neel BG, Kapur R, Chan RJ. The PI3K catalytic subunit p110-delta is a crucial mediator of leukemia-associated mutant PTPN11 -induced GM-CSF hypersensitivity F1000research. 3. DOI: 10.7490/F1000Research.1092775.1 |
0.368 |
|
| 2012 |
Chatterjee A, Ghosh J, Ramdas B, Vemula S, Martin H, Mali R, Nabinger SC, Goodwin CB, Boswell HS, Chan RJ, Kapur R. Unraveling a Novel Mechanism of Stat5 Regulation by FAK and Rac1 in Flt3ITD Induced Leukemogenesis Blood. 120: 858-858. DOI: 10.1182/Blood.V120.21.858.858 |
0.548 |
|
| 2012 |
Martin H, Ma P, Chatterjee A, Ramdas B, Sims E, Vlaar C, Dharmawardhane S, Kapur R. Role of p21 Activated Kinase and Specific Guanine Exchange Factors of Rac Gtpases in Oncogenic KIT Induced Systemic Mastocytosis and Acute Myeloid Leukemia Blood. 120: 810-810. DOI: 10.1182/Blood.V120.21.810.810 |
0.56 |
|
| 2012 |
Nabinger SC, Li XJ, Ramdas B, He Y, Zhang X, Richine B, Bowling J, Fukuda S, Goenka S, Liu Z, Feng G, Yu M, Sandusky G, Boswell HS, Zhang Z, ... Kapur R, et al. The Protein Tyrosine Phosphatase, Shp2, Positively Contributes to FLT3-ITD-Induced Malignant Disease in Vivo and Co-Localizes with Nuclear Phospho-STAT5 in FLT3-ITD-Expressing Leukemic Cells. Blood. 120: 2420-2420. DOI: 10.1182/Blood.V120.21.2420.2420 |
0.505 |
|
| 2012 |
Onishi C, Mori S, Hirade T, Abe M, Yamaguchi S, Kapur R, Fukuda S. The Internal-Tandem-Duplication of Flt3 Mutations Augment Chemotaxis in Hematopoietic Cells by Blocking the Down-Regulation of Rho-Associated Kinase That Is Induced by SDF1/CXCR4 Signaling Blood. 120: 1319-1319. DOI: 10.1182/Blood.V120.21.1319.1319 |
0.49 |
|
| 2011 |
Mali RS, Ramdas B, Ma P, Shi J, Munugalavadla V, Sims E, Wei L, Vemula S, Nabinger SC, Goodwin CB, Chan RJ, Traina F, Visconte V, Tiu RV, Lewis TA, ... ... Kapur R, et al. Rho kinase regulates the survival and transformation of cells bearing oncogenic forms of KIT, FLT3, and BCR-ABL. Cancer Cell. 20: 357-69. PMID 21907926 DOI: 10.1016/J.Ccr.2011.07.016 |
0.497 |
|
| 2011 |
Qu P, Yan C, Blum JS, Kapur R, Du H. Myeloid-specific expression of human lysosomal acid lipase corrects malformation and malfunction of myeloid-derived suppressor cells in lal-/- mice. Journal of Immunology (Baltimore, Md. : 1950). 187: 3854-66. PMID 21900179 DOI: 10.4049/Jimmunol.1003358 |
0.509 |
|
| 2011 |
Ma P, Vemula S, Munugalavadla V, Chen J, Sims E, Borneo J, Kondo T, Ramdas B, Mali RS, Li S, Hashino E, Takemoto C, Kapur R. Balanced interactions between Lyn, the p85alpha regulatory subunit of class I(A) phosphatidylinositol-3-kinase, and SHIP are essential for mast cell growth and maturation. Molecular and Cellular Biology. 31: 4052-62. PMID 21791602 DOI: 10.1128/Mcb.05750-11 |
0.489 |
|
| 2011 |
Ma P, Mali RS, Munugalavadla V, Krishnan S, Ramdas B, Sims E, Martin H, Ghosh J, Li S, Chan RJ, Krystal G, Craig AW, Takemoto C, Kapur R. The PI3K pathway drives the maturation of mast cells via microphthalmia transcription factor. Blood. 118: 3459-69. PMID 21791431 DOI: 10.1182/Blood-2011-04-351809 |
0.733 |
|
| 2011 |
Wu X, Chen S, Orlando SA, Yuan J, Kim ET, Munugalavadla V, Mali RS, Kapur R, Yang FC. p85alpha regulates osteoblast differentiation by cross-talking with the MAPK pathway. The Journal of Biological Chemistry. 286: 13512-21. PMID 21324896 DOI: 10.1074/jbc.M110.187351 |
0.409 |
|
| 2011 |
Lee YN, Brandal S, Noel P, Wentzel E, Mendell JT, McDevitt MA, Kapur R, Carter M, Metcalfe DD, Takemoto CM. KIT signaling regulates MITF expression through miRNAs in normal and malignant mast cell proliferation. Blood. 117: 3629-40. PMID 21273305 DOI: 10.1182/blood-2010-07-293548 |
0.335 |
|
| 2011 |
Ma P, Mali R, Zeng L, Martin H, Ramdas B, He Y, Sims E, Ghosh J, Nabinger SC, Li S, Munugalavadla V, Chatterjee A, Sandusky G, Craig A, Bunting KD, ... ... Kapur R, et al. KIT Induced Myeloproliferative Disease Is Dependent on PI3Kinase and SHP2 Phosphatase: Identification of SHP2 As a Druggable Target for Treating MPD and AML Blood. 118: 868-868. DOI: 10.1182/Blood.V118.21.868.868 |
0.508 |
|
| 2010 |
Vemula S, Ramdas B, Hanneman P, Martin J, Beggs HE, Kapur R. Essential role for focal adhesion kinase in regulating stress hematopoiesis. Blood. 116: 4103-15. PMID 20664055 DOI: 10.1182/Blood-2010-01-262790 |
0.496 |
|
| 2010 |
Lasater EA, Li F, Bessler WK, Estes ML, Vemula S, Hingtgen CM, Dinauer MC, Kapur R, Conway SJ, Ingram DA. Genetic and cellular evidence of vascular inflammation in neurofibromin-deficient mice and humans. The Journal of Clinical Investigation. 120: 859-70. PMID 20160346 DOI: 10.1172/Jci41443 |
0.387 |
|
| 2010 |
Vemula S, Shi J, Hanneman P, Wei L, Kapur R. ROCK1 functions as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stability. Blood. 115: 1785-96. PMID 20008297 DOI: 10.1182/Blood-2009-08-237222 |
0.43 |
|
| 2010 |
Benson EA, Goebl MG, Yang FC, Kapur R, McClintick J, Sanghani S, Clapp DW, Harrington MA. Loss of SIMPL compromises TNF-alpha-dependent survival of hematopoietic progenitors. Experimental Hematology. 38: 71-81. PMID 19941935 DOI: 10.1016/J.Exphem.2009.11.006 |
0.327 |
|
| 2009 |
Saadatzadeh MR, Bijangi-Vishehsaraei K, Kapur R, Haneline LS. Distinct roles of stress-activated protein kinases in Fanconi anemia-type C-deficient hematopoiesis. Blood. 113: 2655-60. PMID 19168785 DOI: 10.1182/Blood-2008-09-181420 |
0.477 |
|
| 2009 |
Nabinger SC, He Y, Yin F, Zhang X, Senbanjo L, Fukuda S, Yu M, Feng G, Zhang Z, Kapur R, Chan RJ. Targeting the Protein Phosphatase, Shp2, Reduces FLT3-ITD-Induced Hyperproliferation of Murine Hematopoietic Progenitors. Blood. 114: 827-827. DOI: 10.1182/Blood.V114.22.827.827 |
0.461 |
|
| 2009 |
Mali R, Krishnan S, Baskar R, Munugalavadla V, Sims E, Hanneman P, Kapur R. Differential Role of Class 1A PI 3-Kinase Regulatory Subunits in Mast Cell Growth, Maturation and Survival. Blood. 114: 77-77. DOI: 10.1182/Blood.V114.22.77.77 |
0.735 |
|
| 2009 |
Goodwin CB, Yang Z, Vemula S, Yin F, Kapur R, Chan RJ. Genetic Disruption of the PI3K Regulatory Subunit, p85α Partially Normalizes Gain-of-Function PTPN11-Induced Hypersensitivity to GM-CSF in Hematopoietic Progenitors. Blood. 114: 3968-3968. DOI: 10.1182/Blood.V114.22.3968.3968 |
0.546 |
|
| 2009 |
Mali R, Ramdas B, Munugalavadla V, Sims E, Kapur R. Rho Kinase Inhibitors as Potential Therapeutic Agents for Oncogenic KIT, FLT3, and BCR-ABL Induced Leukemogenesis. Blood. 114: 3909-3909. DOI: 10.1182/Blood.V114.22.3909.3909 |
0.5 |
|
| 2009 |
Vemula S, Ramdas B, Hanneman P, Beggs H, Kapur R. Role of Focal Adhesion Kinase in Myelotoxicity, Inflammatory Stress Response and Myeloid Cell Functions. Blood. 114: 3615-3615. DOI: 10.1182/Blood.V114.22.3615.3615 |
0.48 |
|
| 2009 |
Ma P, Martin H, Sims E, Baskar R, Ghosh J, Kapur R. Role of Intracellular Tyrosine Residues in Oncogenic KIT- Induced Transformamtion. Blood. 114: 1435-1435. DOI: 10.1182/Blood.V114.22.1435.1435 |
0.443 |
|
| 2008 |
Munugalavadla V, Vemula S, Sims EC, Krishnan S, Chen S, Yan J, Li H, Niziolek PJ, Takemoto C, Robling AG, Yang FC, Kapur R. The p85alpha subunit of class IA phosphatidylinositol 3-kinase regulates the expression of multiple genes involved in osteoclast maturation and migration. Molecular and Cellular Biology. 28: 7182-98. PMID 18809581 DOI: 10.1128/Mcb.00920-08 |
0.65 |
|
| 2008 |
Hong L, Ramdas B, Chen J, Harris C, Wojchowski DM, Kapur R. KIT associated intracellular tyrosines play an essential role in EpoR co-signaling. Cellular Signalling. 20: 1513-20. PMID 18538998 DOI: 10.1016/J.Cellsig.2008.04.005 |
0.411 |
|
| 2008 |
Orschell CM, Borneo J, Munugalavadla V, Ma P, Sims E, Ramdas B, Yoder MC, Kapur R. Deficiency of Src family kinases compromises the repopulating ability of hematopoietic stem cells. Experimental Hematology. 36: 655-66. PMID 18346837 DOI: 10.1016/J.Exphem.2008.01.002 |
0.47 |
|
| 2008 |
Munugalavadla V, Sims EC, Chan RJ, Lenz SD, Kapur R. Requirement for p85alpha regulatory subunit of class IA PI3K in myeloproliferative disease driven by an activation loop mutant of KIT. Experimental Hematology. 36: 301-8. PMID 18179858 DOI: 10.1016/J.Exphem.2007.11.008 |
0.465 |
|
| 2008 |
Nabinger SC, Fukuda S, Kapur R, Chan R. The Role of Protein Tyrosine Phosphatase, Shp2, in FLT3-ITD-Induced Leukemogenesis. Blood. 112: 1804-1804. DOI: 10.1182/Blood.V112.11.1804.1804 |
0.417 |
|
| 2007 |
Li Y, Yan J, De P, Chang HC, Yamauchi A, Christopherson KW, Paranavitana NC, Peng X, Kim C, Munugalavadla V, Munugulavadla V, Kapur R, Chen H, Shou W, Stone JC, et al. Rap1a null mice have altered myeloid cell functions suggesting distinct roles for the closely related Rap1a and 1b proteins. Journal of Immunology (Baltimore, Md. : 1950). 179: 8322-31. PMID 18056377 DOI: 10.4049/Jimmunol.179.12.8322 |
0.441 |
|
| 2007 |
Borneo J, Munugalavadla V, Sims EC, Vemula S, Orschell CM, Yoder M, Kapur R. Src family kinase-mediated negative regulation of hematopoietic stem cell mobilization involves both intrinsic and microenvironmental factors. Experimental Hematology. 35: 1026-37. PMID 17588471 DOI: 10.1016/J.Exphem.2007.03.017 |
0.431 |
|
| 2007 |
Thieu VT, Nguyen ET, McCarthy BP, Bruns HA, Kapur R, Chang CH, Kaplan MH. IL-4-stimulated NF-kappaB activity is required for Stat6 DNA binding. Journal of Leukocyte Biology. 82: 370-9. PMID 17513694 DOI: 10.1189/Jlb.1106707 |
0.384 |
|
| 2007 |
Munugalavadla V, Sims EC, Borneo J, Chan RJ, Kapur R. Genetic and pharmacologic evidence implicating the p85 alpha, but not p85 beta, regulatory subunit of PI3K and Rac2 GTPase in regulating oncogenic KIT-induced transformation in acute myeloid leukemia and systemic mastocytosis. Blood. 110: 1612-20. PMID 17483298 DOI: 10.1182/Blood-2006-10-053058 |
0.485 |
|
| 2007 |
Mathur AN, Chang HC, Zisoulis DG, Stritesky GL, Yu Q, O'Malley JT, Kapur R, Levy DE, Kansas GS, Kaplan MH. Stat3 and Stat4 direct development of IL-17-secreting Th cells. Journal of Immunology (Baltimore, Md. : 1950). 178: 4901-7. PMID 17404271 DOI: 10.4049/Jimmunol.178.8.4901 |
0.316 |
|
| 2007 |
Samayawardhena LA, Kapur R, Craig AW. Involvement of Fyn kinase in Kit and integrin-mediated Rac activation, cytoskeletal reorganization, and chemotaxis of mast cells. Blood. 109: 3679-86. PMID 17213284 DOI: 10.1182/Blood-2006-11-057315 |
0.521 |
|
| 2007 |
Munugalavadla V, Sims EC, Lenz SD, Kapur R. Requirement for p85α Regulatory Subunit of Class IA PI3Kinase and Rac2 GTPase in Myeloproliferative Disease Driven by Activation Loop Mutant of KIT. Blood. 110: 89-89. DOI: 10.1182/Blood.V110.11.89.89 |
0.55 |
|
| 2007 |
Ma P, Kapur R. Repression of ROCKII by GATA-1 Inhibits Cell Proliferation during Erythroid Maturation. Blood. 110: 3345-3345. DOI: 10.1182/Blood.V110.11.3345.3345 |
0.554 |
|
| 2007 |
Vemula S, Gandra P, Shi J, O’Malley JT, Ahyi AN, Stritesky G, Yeh N, Kaplan M, Wei L, Kapur R. ROCKI Regulates Critical Functions in Macrophages and Neutrophils. Blood. 110: 2406-2406. DOI: 10.1182/Blood.V110.11.2406.2406 |
0.397 |
|
| 2007 |
Munugalavadla V, Sims E, Shi J, Wei L, Kapur R. ROCKI Regulates Growth, Maturation and Migration of Mast Cells. Blood. 110: 2191-2191. DOI: 10.1182/Blood.V110.11.2191.2191 |
0.545 |
|
| 2007 |
Vemula S, Abratigue BP, Gandra P, O’Malley JT, Ahyi AN, Stritesky G, Yeh N, Kaplan M, Beggs H, Kapur R. Focal Adhesion Kinase Regulates Critical Functions in Hematopoiesis. Blood. 110: 1407-1407. DOI: 10.1182/Blood.V110.11.1407.1407 |
0.467 |
|
| 2006 |
Mathur AN, Chang HC, Zisoulis DG, Kapur R, Belladonna ML, Kansas GS, Kaplan MH. T-bet is a critical determinant in the instability of the IL-17-secreting T-helper phenotype. Blood. 108: 1595-601. PMID 16670261 DOI: 10.1182/Blood-2006-04-015016 |
0.324 |
|
| 2006 |
Li B, Jia N, Kapur R, Chun KT. Cul4A targets p27 for degradation and regulates proliferation, cell cycle exit, and differentiation during erythropoiesis. Blood. 107: 4291-9. PMID 16467204 DOI: 10.1182/Blood-2005-08-3349 |
0.491 |
|
| 2006 |
Wang ZY, Kusam S, Munugalavadla V, Kapur R, Brutkiewicz RR, Dent AL. Regulation of Th2 cytokine expression in NKT cells: unconventional use of Stat6, GATA-3, and NFAT2. Journal of Immunology (Baltimore, Md. : 1950). 176: 880-8. PMID 16393972 DOI: 10.4049/Jimmunol.176.2.880 |
0.416 |
|
| 2006 |
Haneline LS, White H, Yang FC, Chen S, Orschell C, Kapur R, Ingram DA. Genetic reduction of class IA PI-3 kinase activity alters fetal hematopoiesis and competitive repopulating ability of hematopoietic stem cells in vivo. Blood. 107: 1375-82. PMID 16239435 DOI: 10.1182/Blood-2005-05-1985 |
0.442 |
|
| 2006 |
Lee Y, Noel P, Shahlaee A, Carter M, Kapur R, Wayne A, Metcalfe DD, Takemoto C. Kit Signaling Regulates Mitf Expression in Mastocytosis. Blood. 108: 3601-3601. DOI: 10.1182/Blood.V108.11.3601.3601 |
0.532 |
|
| 2005 |
Bijangi-Vishehsaraei K, Saadatzadeh MR, Werne A, McKenzie KA, Kapur R, Ichijo H, Haneline LS. Enhanced TNF-alpha-induced apoptosis in Fanconi anemia type C-deficient cells is dependent on apoptosis signal-regulating kinase 1. Blood. 106: 4124-30. PMID 16109778 DOI: 10.1182/Blood-2005-05-2096 |
0.427 |
|
| 2005 |
Munugalavadla V, Dore LC, Tan BL, Hong L, Vishnu M, Weiss MJ, Kapur R. Repression of c-kit and its downstream substrates by GATA-1 inhibits cell proliferation during erythroid maturation. Molecular and Cellular Biology. 25: 6747-59. PMID 16024808 DOI: 10.1128/Mcb.25.15.6747-6759.2005 |
0.516 |
|
| 2005 |
Munugalavadla V, Kapur R. Role of c-Kit and erythropoietin receptor in erythropoiesis. Critical Reviews in Oncology/Hematology. 54: 63-75. PMID 15780908 DOI: 10.1016/J.Critrevonc.2004.11.005 |
0.424 |
|
| 2005 |
Munugalavadla V, Borneo J, Ingram DA, Kapur R. p85alpha subunit of class IA PI-3 kinase is crucial for macrophage growth and migration. Blood. 106: 103-9. PMID 15769893 DOI: 10.1182/Blood-2004-10-4041 |
0.449 |
|
| 2005 |
Chan RJ, Leedy MB, Munugalavadla V, Voorhorst CS, Li Y, Yu M, Kapur R. Human somatic PTPN11 mutations induce hematopoietic-cell hypersensitivity to granulocyte-macrophage colony-stimulating factor. Blood. 105: 3737-42. PMID 15644411 DOI: 10.1182/Blood-2004-10-4002 |
0.456 |
|
| 2005 |
Chen J, Vemula S, Kapur R. Structure Function Analysis of Hematopoietic Specific Src Family Kinases Lyn, Hck and Fgr Reveal a Critical Role for Lyn’s Unique Domain in Regulating Growth of Myeloid Cells That Is Distinct from the Role of Hck and Fgr’s Unique Domain. Blood. 106: 68-68. DOI: 10.1182/Blood.V106.11.68.68 |
0.467 |
|
| 2005 |
Munugalavadla V, Sims E, Borneo J, Kapur R. Gleevec Resistant Activating Mutation of c-Kit (D816V) Demonstrates Ligand Independent Growth and Promiscuous Cooperation with Multiple Cytokine Receptors Via the p85α Subunit of Class IA PI-3Kinase. Blood. 106: 3530-3530. DOI: 10.1182/Blood.V106.11.3530.3530 |
0.464 |
|
| 2005 |
Munugalavadla V, Sims E, Ingram DA, Robling A, Kapur R. p85α Regulatory Subunit of Class IA PI-3Kinase Regulates Osteoclast Function(s) and Bone Mass. Blood. 106: 2223-2223. DOI: 10.1182/Blood.V106.11.2223.2223 |
0.42 |
|
| 2004 |
Hiatt K, Ingram DA, Huddleston H, Spandau DF, Kapur R, Clapp DW. Loss of the nf1 tumor suppressor gene decreases fas antigen expression in myeloid cells. The American Journal of Pathology. 164: 1471-9. PMID 15039234 DOI: 10.1016/S0002-9440(10)63233-6 |
0.449 |
|
| 2004 |
Hong L, Munugalavadla V, Kapur R. c-Kit-mediated overlapping and unique functional and biochemical outcomes via diverse signaling pathways. Molecular and Cellular Biology. 24: 1401-10. PMID 14729982 DOI: 10.1128/Mcb.24.3.1401-1410.2004 |
0.428 |
|
| 2004 |
Munugalavadla V, Borneo J, Chen J, Kapur R. Opposing Roles for Class IA PI-3Kinase and Src Family Kinase in Regulating Myeloid Cell Growth and Lineage Commitment. Blood. 104: 3543-3543. DOI: 10.1182/Blood.V104.11.3543.3543 |
0.522 |
|
| 2004 |
Li K, Karur V, Vincent B, Curato J, Kapur R, Besmer P, Wojchowski DM. Kit PY567- Directed Signals Are Important for Efficient Erythroid Progenitor Cell Proliferation and Survival, and Are Attenuated by Kit PY569. Blood. 104: 2168-2168. DOI: 10.1182/Blood.V104.11.2168.2168 |
0.504 |
|
| 2004 |
Munugalavadla V, Hong L, White H, Ingram DA, Kapur R. Differential Role forpP85α and p85β Regulatory Subunits of Class IA PI-3Kinase in Mast Cell Growth and Maturation. Blood. 104: 2162-2162. DOI: 10.1182/Blood.V104.11.2162.2162 |
0.518 |
|
| 2004 |
Borneo J, Orschell CM, Munugalavadla V, Kapur R. Genetic Evidence for a Role of Src Kinases in Mobilization, Homing and Engraftment of Hematopoietic Stem Cells: Deficiency of Src Kinases Results in Enhanced G-CSF Induced Mobilization. Blood. 104: 1292-1292. DOI: 10.1182/Blood.V104.11.1292.1292 |
0.489 |
|
| 2003 |
Yang FC, Ingram DA, Chen S, Hingtgen CM, Ratner N, Monk KR, Clegg T, White H, Mead L, Wenning MJ, Williams DA, Kapur R, Atkinson SJ, Clapp DW. Neurofibromin-deficient Schwann cells secrete a potent migratory stimulus for Nf1+/- mast cells. The Journal of Clinical Investigation. 112: 1851-61. PMID 14679180 DOI: 10.1172/Jci19195 |
0.319 |
|
| 2003 |
Chandra S, Kapur R, Chuzhanova N, Summey V, Prentice D, Barker J, Cooper DN, Williams DA. A rare complex DNA rearrangement in the murine Steel gene results in exon duplication and a lethal phenotype. Blood. 102: 3548-55. PMID 12881302 DOI: 10.1182/Blood-2003-05-1468 |
0.365 |
|
| 2003 |
Huddleston H, Tan B, Yang FC, White H, Wenning MJ, Orazi A, Yoder MC, Kapur R, Ingram DA. Functional p85alpha gene is required for normal murine fetal erythropoiesis. Blood. 102: 142-5. PMID 12623844 DOI: 10.1182/Blood-2002-10-3245 |
0.377 |
|
| 2003 |
Tan BL, Yazicioglu MN, Ingram D, McCarthy J, Borneo J, Williams DA, Kapur R. Genetic evidence for convergence of c-Kit- and alpha4 integrin-mediated signals on class IA PI-3kinase and the Rac pathway in regulating integrin-directed migration in mast cells. Blood. 101: 4725-32. PMID 12560232 DOI: 10.1182/Blood-2002-08-2521 |
0.504 |
|
| 2003 |
Tan BL, Hong L, Munugalavadla V, Kapur R. Functional and biochemical consequences of abrogating the activation of multiple diverse early signaling pathways in Kit. Role for Src kinase pathway in Kit-induced cooperation with erythropoietin receptor. The Journal of Biological Chemistry. 278: 11686-95. PMID 12486028 DOI: 10.1074/Jbc.M207068200 |
0.425 |
|
| 2003 |
Xie X, Chan RJ, Johnson SA, Starr M, McCarthy J, Kapur R, Yoder MC. Thrombopoietin promotes mixed lineage and megakaryocytic colony-forming cell growth but inhibits primitive and definitive erythropoiesis in cells isolated from early murine yolk sacs. Blood. 101: 1329-35. PMID 12393382 DOI: 10.1182/Blood-2002-05-1468 |
0.365 |
|
| 2002 |
Kapur R, Chandra S, Cooper R, McCarthy J, Williams DA. Role of p38 and ERK MAP kinase in proliferation of erythroid progenitors in response to stimulation by soluble and membrane isoforms of stem cell factor. Blood. 100: 1287-93. PMID 12149209 DOI: 10.1182/Blood.V100.4.1287.H81602001287_1287_1293 |
0.49 |
|
| 2002 |
Marques SA, Dy LC, Southall MD, Yi Q, Smietana E, Kapur R, Marques M, Travers JB, Spandau DF. The platelet-activating factor receptor activates the extracellular signal-regulated kinase mitogen-activated protein kinase and induces proliferation of epidermal cells through an epidermal growth factor-receptor-dependent pathway. The Journal of Pharmacology and Experimental Therapeutics. 300: 1026-35. PMID 11861812 DOI: 10.1124/Jpet.300.3.1026 |
0.379 |
|
| 2001 |
Kapur R, Cooper R, Zhang L, Williams DA. Cross-talk between alpha(4)beta(1)/alpha(5)beta(1) and c-Kit results in opposing effect on growth and survival of hematopoietic cells via the activation of focal adhesion kinase, mitogen-activated protein kinase, and Akt signaling pathways. Blood. 97: 1975-81. PMID 11264161 DOI: 10.1182/Blood.V97.7.1975 |
0.429 |
|
| 2001 |
Kapur R, Zhang L. A novel mechanism of cooperation between c-Kit and erythropoietin receptor. Stem cell factor induces the expression of Stat5 and erythropoietin receptor, resulting in efficient proliferation and survival by erythropoietin. The Journal of Biological Chemistry. 276: 1099-106. PMID 11042182 DOI: 10.1074/Jbc.M007442200 |
0.438 |
|
| 2000 |
Smitherman M, Lee K, Swanger J, Kapur R, Clurman BE. Characterization and targeted disruption of murine Nup50, a p27(Kip1)-interacting component of the nuclear pore complex. Molecular and Cellular Biology. 20: 5631-42. PMID 10891500 DOI: 10.1128/Mcb.20.15.5631-5642.2000 |
0.31 |
|
| 2000 |
Yang FC, Kapur R, King AJ, Tao W, Kim C, Borneo J, Breese R, Marshall M, Dinauer MC, Williams DA. Rac2 stimulates Akt activation affecting BAD/Bcl-XL expression while mediating survival and actin function in primary mast cells. Immunity. 12: 557-68. PMID 10843388 DOI: 10.1016/S1074-7613(00)80207-1 |
0.389 |
|
| 2000 |
Yang F, Kapur R, King A, Tao W, Borneo J, Williams D. RAC2 Regulates the activation of akt and the balance between pro- and anti-apoptotic proteins bad and bcl-xl Experimental Hematology. 28: 67. DOI: 10.1016/S0301-472X(00)00298-8 |
0.515 |
|
| 1999 |
Roberts AW, Kim C, Zhen L, Lowe JB, Kapur R, Petryniak B, Spaetti A, Pollock JD, Borneo JB, Bradford GB, Atkinson SJ, Dinauer MC, Williams DA. Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense. Immunity. 10: 183-96. PMID 10072071 DOI: 10.1016/S1074-7613(00)80019-9 |
0.355 |
|
| 1999 |
Kapur R, Cooper R, Xiao X, Weiss MJ, Donovan P, Williams DA. The Presence of Novel Amino Acids in the Cytoplasmic Domain of Stem Cell Factor Results in Hematopoietic Defects inSteel17H Mice Blood. 94: 1915-1925. DOI: 10.1182/blood.v94.6.1915.418k11_1915_1925 |
0.395 |
|
| 1999 |
Kapur R, Cooper R, Xiao X, Weiss MJ, Donovan P, Williams DA. The Presence of Novel Amino Acids in the Cytoplasmic Domain of Stem Cell Factor Results in Hematopoietic Defects inSteel17H Mice Blood. 94: 1915-1925. DOI: 10.1182/Blood.V94.6.1915 |
0.395 |
|
| 1998 |
Kapur R, Majumdar M, Xiao X, McAndrews-Hill M, Schindler K, Williams DA. Signaling Through the Interaction of Membrane-Restricted Stem Cell Factor and c-kit Receptor Tyrosine Kinase: Genetic Evidence for a Differential Role in Erythropoiesis Blood. 91: 879-889. DOI: 10.1182/Blood.V91.3.879.879_879_889 |
0.517 |
|
| 1997 |
Kapur R, Everett ET, Uffman J, McAndrews-Hill M, Cooper R, Ryder J, Vik T, Williams DA. Overexpression of Human Stem Cell Factor Impairs Melanocyte, Mast Cell, and Thymocyte Development: A Role for Receptor Tyrosine Kinase-Mediated Mitogen Activated Protein Kinase Activation in Cell Differentiation Blood. 90: 3018-3026. DOI: 10.1182/Blood.V90.8.3018 |
0.497 |
|
| 1996 |
Majumdar M, Everett E, Xiao X, Cooper R, Langley K, Kapur R, Vik T, Williams D. Xenogeneic expression of human stem cell factor in transgenic mice mimics codominant c-kit mutations Blood. 87: 3203-3211. DOI: 10.1182/Blood.V87.8.3203.Bloodjournal8783203 |
0.464 |
|
| 1996 |
Maze R, Kapur R, Williams DA. Genetically modified hematopoietic stem cells expressing o6methylguanine dna methyltransferase via a retrovirus vector protect the lymphoid and stem cell compartments in long-term engrafted animals treated with nitrosourea Journal of Investigative Medicine. 44. |
0.319 |
|
| 1994 |
Kapur R, Evans DL, Harris DT. Evolutionary conservation of a human function-associated molecule on murine natural killer cells: expression and function. Scandinavian Journal of Immunology. 40: 50-6. PMID 8029643 DOI: 10.1111/J.1365-3083.1994.Tb03432.X |
0.321 |
|
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