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Jennifer E Van Eyk - Publications

Affiliations: 
1996-2003 Physiology Queen's University, Canada, Kingston, Ontario, Canada 
 2003-2014 Johns Hopkins University, Baltimore, MD 
 2014- Cedars-Sinai, Los Angeles, CA, United States 
Area:
Biochemistry
Website:
http://bio.csmc.edu/view/15171/Jennifer-Van-Eyk.aspx
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Year Citation  Score
2023 Matlock AD, Vaibhav V, Holewinski R, Venkatraman V, Dardov V, Manalo DM, Shelley B, Ornelas L, Banuelos M, Mandefro B, Escalante-Chong R, Li J, Finkbeiner S, Fraenkel E, Rothstein J, ... ... Van Eyk JE, et al. NeuroLINCS Proteomics: Defining human-derived iPSC proteomes and protein signatures of pluripotency. Scientific Data. 10: 24. PMID 36631473 DOI: 10.1038/s41597-022-01687-7  0.77
2022 Baxi EG, Thompson T, Li J, Kaye JA, Lim RG, Wu J, Ramamoorthy D, Lima L, Vaibhav V, Matlock A, Frank A, Coyne AN, Landin B, Ornelas L, Mosmiller E, ... ... Van Eyk JE, et al. Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines. Nature Neuroscience. 25: 226-237. PMID 35115730 DOI: 10.1038/s41593-021-01006-0  0.465
2021 Li J, Lim RG, Kaye JA, Dardov V, Coyne AN, Wu J, Milani P, Cheng A, Thompson TG, Ornelas L, Frank A, Adam M, Banuelos MG, Casale M, ... ... Van Eyk JE, et al. An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients. Iscience. 24: 103221. PMID 34746695 DOI: 10.1016/j.isci.2021.103221  0.757
2021 Kammers K, Taub MA, Mathias RA, Yanek LR, Kanchan K, Venkatraman V, Sundararaman N, Martin J, Liu S, Hoyle D, Raedschelders K, Holewinski R, Parker S, Dardov V, Faraday N, ... ... Van Eyk JE, et al. Gene and protein expression in human megakaryocytes derived from induced pluripotent stem cells. Journal of Thrombosis and Haemostasis : Jth. PMID 33829634 DOI: 10.1111/jth.15334  0.759
2020 Adhikari S, Nice EC, Deutsch EW, Lane L, Omenn GS, Pennington SR, Paik YK, Overall CM, Corrales FJ, Cristea IM, Van Eyk JE, Uhlén M, Lindskog C, Chan DW, Bairoch A, et al. A high-stringency blueprint of the human proteome. Nature Communications. 11: 5301. PMID 33067450 DOI: 10.1038/s41467-020-19045-9  0.606
2019 Vatine GD, Barrile R, Workman MJ, Sances S, Barriga BK, Rahnama M, Barthakur S, Kasendra M, Lucchesi C, Kerns J, Wen N, Spivia WR, Chen Z, Van Eyk J, Svendsen CN. Human iPSC-Derived Blood-Brain Barrier Chips Enable Disease Modeling and Personalized Medicine Applications. Cell Stem Cell. 24: 995-1005.e6. PMID 31173718 DOI: 10.1016/j.stem.2019.05.011  0.448
2018 Jones MK, Lu B, Chen DZ, Spivia WR, Mercedo A, Ljubimov AV, Svendsen CN, Van Eyk JE, Wang S. In vitro and in vivo Proteomic Comparison of Human Neural Progenitor Cell-Induced Photoreceptor Survival. Proteomics. e1800213. PMID 30515959 DOI: 10.1002/pmic.201800213  0.444
2018 Nicolas A, Kenna KP, Renton AE, Ticozzi N, Faghri F, Chia R, Dominov JA, Kenna BJ, Nalls MA, Keagle P, Rivera AM, van Rheenen W, Murphy NA, van Vugt JJFA, Geiger JT, ... Van Eyk JE, et al. Genome-wide Analyses Identify KIF5A as a Novel ALS Gene. Neuron. 97: 1268-1283.e6. PMID 29566793 DOI: 10.1016/J.Neuron.2018.02.027  0.484
2018 Keenan AB, Jenkins SL, Jagodnik KM, Koplev S, He E, Torre D, Wang Z, Dohlman AB, Silverstein MC, Lachmann A, Kuleshov MV, Ma'ayan A, Stathias V, Terryn R, Cooper D, ... Van Eyk JE, et al. The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations. Cell Systems. 6: 13-24. PMID 29199020 DOI: 10.1016/J.Cels.2017.11.001  0.762
2017 Vatine GD, Al-Ahmad A, Barriga BK, Svendsen S, Salim A, Garcia L, Garcia VJ, Ho R, Yucer N, Qian T, Lim RG, Wu J, Thompson LM, Spivia WR, Chen Z, ... Van Eyk J, et al. Modeling Psychomotor Retardation using iPSCs from MCT8-Deficient Patients Indicates a Prominent Role for the Blood-Brain Barrier. Cell Stem Cell. PMID 28526555 DOI: 10.1016/J.Stem.2017.04.002  0.442
2015 Lindsey ML, Mayr M, Gomes AV, Delles C, Arrell DK, Murphy AM, Lange RA, Costello CE, Jin YF, Laskowitz DT, Sam F, Terzic A, Van Eyk J, Srinivas PR. Transformative Impact of Proteomics on Cardiovascular Health and Disease: A Scientific Statement From the American Heart Association. Circulation. 132: 852-72. PMID 26195497 DOI: 10.1161/Cir.0000000000000226  0.711
2015 Bausch-Fluck D, Hofmann A, Bock T, Frei AP, Cerciello F, Jacobs A, Moest H, Omasits U, Gundry RL, Yoon C, Schiess R, Schmidt A, Mirkowska P, Härtlová A, Van Eyk JE, et al. A mass spectrometric-derived cell surface protein atlas. Plos One. 10: e0121314. PMID 25894527 DOI: 10.1371/Journal.Pone.0121314  0.615
2015 Wijnker PJ, Li Y, Zhang P, Foster DB, dos Remedios C, Van Eyk JE, Stienen GJ, Murphy AM, van der Velden J. A novel phosphorylation site, Serine 199, in the C-terminus of cardiac troponin I regulates calcium sensitivity and susceptibility to calpain-induced proteolysis. Journal of Molecular and Cellular Cardiology. 82: 93-103. PMID 25771144 DOI: 10.1016/j.yjmcc.2015.03.006  0.615
2012 Gao WD, Murray CI, Tian Y, Zhong X, DuMond JF, Shen X, Stanley BA, Foster DB, Wink DA, King SB, Van Eyk JE, Paolocci N. Nitroxyl-mediated disulfide bond formation between cardiac myofilament cysteines enhances contractile function. Circulation Research. 111: 1002-11. PMID 22851540 DOI: 10.1161/Circresaha.112.270827  0.611
2012 Husberg C, Agnetti G, Holewinski RJ, Christensen G, Van Eyk JE. Dephosphorylation of cardiac proteins in vitro - a matter of phosphatase specificity. Proteomics. 12: 973-8. PMID 22522803 DOI: 10.1002/pmic.201100116  0.328
2012 Gundry RL, Riordon DR, Tarasova Y, Chuppa S, Bhattacharya S, Juhasz O, Wiedemeier O, Milanovich S, Noto FK, Tchernyshyov I, Raginski K, Bausch-Fluck D, Tae HJ, Marshall S, Duncan SA, ... ... Van Eyk JE, et al. A cell surfaceome map for immunophenotyping and sorting pluripotent stem cells. Molecular & Cellular Proteomics : McP. 11: 303-16. PMID 22493178 DOI: 10.1074/Mcp.M112.018135  0.607
2011 O'Rourke B, Van Eyk JE, Foster DB. Mitochondrial protein phosphorylation as a regulatory modality: implications for mitochondrial dysfunction in heart failure. Congestive Heart Failure (Greenwich, Conn.). 17: 269-82. PMID 22103918 DOI: 10.1111/j.1751-7133.2011.00266.x  0.597
2011 Wang SB, Foster DB, Rucker J, O'Rourke B, Kass DA, Van Eyk JE. Redox regulation of mitochondrial ATP synthase: implications for cardiac resynchronization therapy. Circulation Research. 109: 750-7. PMID 21817160 DOI: 10.1161/CIRCRESAHA.111.246124  0.583
2011 Cammarato A, Ahrens CH, Alayari NN, Qeli E, Rucker J, Reedy MC, Zmasek CM, Gucek M, Cole RN, Van Eyk JE, Bodmer R, O'Rourke B, Bernstein SI, Foster DB. A mighty small heart: the cardiac proteome of adult Drosophila melanogaster. Plos One. 6: e18497. PMID 21541028 DOI: 10.1371/Journal.Pone.0018497  0.656
2010 Gundry RL, Tchernyshyov I, Sheng S, Tarasova Y, Raginski K, Boheler KR, Van Eyk JE. Expanding the mouse embryonic stem cell proteome: combining three proteomic approaches. Proteomics. 10: 2728-32. PMID 20512790 DOI: 10.1002/Pmic.201000039  0.643
2010 Hesketh GG, Shah MH, Halperin VL, Cooke CA, Akar FG, Yen TE, Kass DA, Machamer CE, Van Eyk JE, Tomaselli GF. Ultrastructure and regulation of lateralized connexin43 in the failing heart. Circulation Research. 106: 1153-63. PMID 20167932 DOI: 10.1161/Circresaha.108.182147  0.579
2010 Galińska A, Hatch V, Craig R, Murphy AM, Van Eyk JE, Wang CL, Lehman W, Foster DB. The C terminus of cardiac troponin I stabilizes the Ca2+-activated state of tropomyosin on actin filaments. Circulation Research. 106: 705-11. PMID 20035081 DOI: 10.1161/Circresaha.109.210047  0.606
2010 Cammarato A, Alayari NN, Gucek M, Reedy MC, Rucker J, Van Eyk JE, Cole RN, O'Rourke B, Bodmer R, Bernstein SI, Foster DB. A Systems Biology Approach to Restrictive Cardiomyopathy in Drosophila Biophysical Journal. 98: 717a-718a. DOI: 10.1016/J.Bpj.2009.12.3933  0.656
2009 Gundry RL, White MY, Murray CI, Kane LA, Fu Q, Stanley BA, Van Eyk JE. Preparation of proteins and peptides for mass spectrometry analysis in a bottom-up proteomics workflow. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit10.25. PMID 19816929 DOI: 10.1002/0471142727.Mb1025S88  0.612
2009 Hesketh GG, Van Eyk JE, Tomaselli GF. Mechanisms of gap junction traffic in health and disease. Journal of Cardiovascular Pharmacology. 54: 263-72. PMID 19701097 DOI: 10.1097/Fjc.0B013E3181Ba0811  0.599
2009 Gundry RL, Raginski K, Tarasova Y, Tchernyshyov I, Bausch-Fluck D, Elliott ST, Boheler KR, Van Eyk JE, Wollscheid B. The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation. Molecular & Cellular Proteomics : McP. 8: 2555-69. PMID 19656770 DOI: 10.1074/Mcp.M900195-Mcp200  0.625
2009 Hsu K, Chi N, Gucek M, Van Eyk JE, Cole RN, Lin M, Foster DB. Miltenberger blood group antigen type III (Mi.III) enhances the expression of band 3. Blood. 114: 1919-28. PMID 19564639 DOI: 10.1182/blood-2008-12-195180  0.552
2009 Foster DB, Van Eyk JE, Marbán E, O'Rourke B. Redox signaling and protein phosphorylation in mitochondria: progress and prospects. Journal of Bioenergetics and Biomembranes. 41: 159-68. PMID 19440831 DOI: 10.1007/s10863-009-9217-7  0.619
2009 Gundry RL, White MY, Nogee J, Tchernyshyov I, Van Eyk JE. Assessment of albumin removal from an immunoaffinity spin column: critical implications for proteomic examination of the albuminome and albumin-depleted samples. Proteomics. 9: 2021-8. PMID 19294703 DOI: 10.1002/Pmic.200800686  0.601
2009 Alayari NN, Cammarato A, Reedy MC, O'Rourke B, Van Eyk J, Rucker J, Bodmer R, Bernstein SI, Foster DB. Structural and Proteomic Analysis of the Drosophila Cardiac Tube Biophysical Journal. 96: 502a. DOI: 10.1016/J.Bpj.2008.12.2590  0.645
2009 Galinska-Rakoczy A, Hatch V, Craig R, Murphy AM, Van Eyk JE, Wang CA, Lehman W, Foster DB. EM and 3D-Reconstruction of Thin Filaments Reconstituted with Truncated Troponin I Associated with Myocardial Stunning Biophysical Journal. 96: 502a. DOI: 10.1016/J.Bpj.2008.12.2588  0.576
2008 Gundry RL, Boheler KR, Van Eyk JE, Wollscheid B. A novel role for proteomics in the discovery of cell-surface markers on stem cells: Scratching the surface. Proteomics. Clinical Applications. 2: 892-903. PMID 19526049 DOI: 10.1002/Prca.200780122  0.608
2008 Foster DB, O'Rourke B, Van Eyk JE. What can mitochondrial proteomics tell us about cardioprotection afforded by preconditioning? Expert Review of Proteomics. 5: 633-6. PMID 18937553 DOI: 10.1586/14789450.5.5.633  0.545
2008 Mathivanan S, Ahmed M, Ahn NG, Alexandre H, Amanchy R, Andrews PC, Bader JS, Balgley BM, Bantscheff M, Bennett KL, Björling E, Blagoev B, Bose R, Brahmachari SK, Burlingame AS, ... Van Eyk J, et al. Human Proteinpedia enables sharing of human protein data. Nature Biotechnology. 26: 164-7. PMID 18259167 DOI: 10.1038/Nbt0208-164  0.424
2008 Warburton S, White MY, Van Eyk JE, Cotter RJ, Ping P, Dunn MJ, Vondriska TM. Cardiovascular Initiative of the Human Proteome Organisation, 5th Workshop October 2007, Seoul, Korea. Proteomics. 8: 924-6. PMID 18240139 DOI: 10.1002/Pmic.200701083  0.431
2007 Gundry RL, Fu Q, Jelinek CA, Van Eyk JE, Cotter RJ. Investigation of an albumin-enriched fraction of human serum and its albuminome. Proteomics. Clinical Applications. 1: 73-88. PMID 20204147 DOI: 10.1002/Prca.200600276  0.705
2007 Gundry RL, Van Eyk JE. Unraveling the complexity of circulating forms of brain natriuretic peptide. Clinical Chemistry. 53: 1181-2. PMID 17582147 DOI: 10.1373/Clinchem.2007.086611  0.618
2007 Agnetti G, Kane LA, Guarnieri C, Caldarera CM, Van Eyk JE. Proteomic technologies in the study of kinases: novel tools for the investigation of PKC in the heart. Pharmacological Research. 55: 511-22. PMID 17548206 DOI: 10.1016/j.phrs.2007.04.012  0.303
2007 Bovenkamp DE, Stanley BA, Van Eyk JE. Optimization of cardiac troponin I pull-down by IDM affinity beads and SELDI. Methods in Molecular Biology (Clifton, N.J.). 357: 91-102. PMID 17172682 DOI: 10.1385/1-59745-214-9:91  0.313
2007 Hesketh GG, Shah M, Guo Y, Tomaselli GF, Van Eyk JE, Hopkins J. Phosphorylation dependent targeting of connexin 43 to lipid rafts is increased in heart failure Journal of Molecular and Cellular Cardiology. 42: S146. DOI: 10.1016/J.Yjmcc.2007.03.476  0.539
2006 Narolska NA, Piroddi N, Belus A, Boontje NM, Scellini B, Deppermann S, Zaremba R, Musters RJ, dos Remedios C, Jaquet K, Foster DB, Murphy AM, van Eyk JE, Tesi C, Poggesi C, et al. Impaired diastolic function after exchange of endogenous troponin I with C-terminal truncated troponin I in human cardiac muscle. Circulation Research. 99: 1012-20. PMID 17023673 DOI: 10.1161/01.RES.0000248753.30340.af  0.639
2006 Arrell DK, Elliott ST, Kane LA, Guo Y, Ko YH, Pedersen PL, Robinson J, Murata M, Murphy AM, Marbán E, Van Eyk JE. Proteomic analysis of pharmacological preconditioning: novel protein targets converge to mitochondrial metabolism pathways. Circulation Research. 99: 706-14. PMID 16946135 DOI: 10.1161/01.RES.0000243995.74395.f8  0.73
2005 Buscemi N, Murray C, Doherty-Kirby A, Lajoie G, Sussman MA, Van Eyk JE. Myocardial subproteomic analysis of a constitutively active Rac1-expressing transgenic mouse with lethal myocardial hypertrophy. American Journal of Physiology. Heart and Circulatory Physiology. 289: H2325-33. PMID 16155095 DOI: 10.1152/Ajpheart.01041.2004  0.754
2005 Simpson JA, Labugger R, Collier C, Brison RJ, Iscoe S, Van Eyk JE. Fast and slow skeletal troponin I in serum from patients with various skeletal muscle disorders: a pilot study. Clinical Chemistry. 51: 966-72. PMID 15833785 DOI: 10.1373/Clinchem.2004.042671  0.734
2004 McDonough JL, Van Eyk JE. Developing the next generation of cardiac markers: disease-induced modifications of troponin I. Progress in Cardiovascular Diseases. 47: 207-16. PMID 15736586  0.319
2004 Stanley BA, Gundry RL, Cotter RJ, Van Eyk JE. Heart disease, clinical proteomics and mass spectrometry. Disease Markers. 20: 167-78. PMID 15502250 DOI: 10.1155/2004/965261  0.715
2003 Li MX, Wang X, Lindhout DA, Buscemi N, Van Eyk JE, Sykes BD. Phosphorylation and mutation of human cardiac troponin I deferentially destabilize the interaction of the functional regions of troponin I with troponin C. Biochemistry. 42: 14460-8. PMID 14661957 DOI: 10.1021/Bi035408Y  0.721
2003 Buscemi N, Doherty-Kirby A, Sussman MA, Lajoie G, Van Eyk JE. Proteomic analysis of Rac1 transgenic mice displaying dilated cardiomyopathy reveals an increase in creatine kinase M-chain protein abundance. Molecular and Cellular Biochemistry. 251: 145-51. PMID 14575316 DOI: 10.1007/978-1-4419-9238-3_20  0.748
2003 Foster DB, Noguchi T, VanBuren P, Murphy AM, Van Eyk JE. C-terminal truncation of cardiac troponin I causes divergent effects on ATPase and force: implications for the pathophysiology of myocardial stunning. Circulation Research. 93: 917-24. PMID 14551240 DOI: 10.1161/01.RES.0000099889.35340.6F  0.615
2003 Labugger R, Simpson JA, Quick M, Brown HA, Collier CE, Neverova I, Van Eyk JE. Strategy for analysis of cardiac troponins in biological samples with a combination of affinity chromatography and mass spectrometry. Clinical Chemistry. 49: 873-9. PMID 12765982 DOI: 10.1373/49.6.873  0.758
2002 Buscemi N, Foster DB, Neverova I, Van Eyk JE. p21-activated kinase increases the calcium sensitivity of rat triton-skinned cardiac muscle fiber bundles via a mechanism potentially involving novel phosphorylation of troponin I. Circulation Research. 91: 509-16. PMID 12242269  0.793
2002 Labugger R, McDonough JL, Neverova I, Van Eyk JE. Solubilization, two-dimensional separation and detection of the cardiac myofilament protein troponin T. Proteomics. 2: 673-8. PMID 12112847 DOI: 10.1002/1615-9861(200206)2:6<673::Aid-Prot673>3.0.Co;2-2  0.768
2002 Simpson JA, Labugger R, Hesketh GG, D'Arsigny C, O'Donnell D, Matsumoto N, Collier CP, Iscoe S, Van Eyk JE. Differential detection of skeletal troponin I isoforms in serum of a patient with rhabdomyolysis: markers of muscle injury? Clinical Chemistry. 48: 1112-4. PMID 12089186 DOI: 10.1093/Clinchem/48.7.1112  0.78
2001 Arrell DK, Neverova I, Fraser H, Marbán E, Van Eyk JE. Proteomic analysis of pharmacologically preconditioned cardiomyocytes reveals novel phosphorylation of myosin light chain 1. Circulation Research. 89: 480-7. PMID 11557734  0.72
2001 Arrell DK, Neverova I, Van Eyk JE. Cardiovascular proteomics evolution and potential Circulation Research. 88: 763-773. PMID 11325867  0.731
2001 Davis GK, Labugger R, Van Eyk JE, Apple FS. Cardiac troponin T is not detected in western blots of diseased renal tissue Clinical Chemistry. 47: 782-783. PMID 11274043 DOI: 10.1093/Clinchem/47.4.782  0.76
2001 McDonough JL, Labugger R, Pickett W, Tse MY, MacKenzie S, Pang SC, Atar D, Ropchan G, Van Eyk JE. Cardiac troponin I is modified in the myocardium of bypass patients. Circulation. 103: 58-64. PMID 11136686 DOI: 10.1161/01.Cir.103.1.58  0.752
2000 Labugger R, Organ L, Collier C, Atar D, Van Eyk JE. Extensive troponin I and T modification detected in serum from patients with acute myocardial infarction. Circulation. 102: 1221-6. PMID 10982534  0.741
2000 Rembold CM, Foster DB, Strauss JD, Wingard CJ, Van Eyk JE. cGMP-mediated phosphorylation of heat shock protein 20 may cause smooth muscle relaxation without myosin light chain dephosphorylation in swine carotid artery Journal of Physiology. 524: 865-878. PMID 10790164 DOI: 10.1111/J.1469-7793.2000.00865.X  0.597
2000 Foster DB, Shen LH, Kelly J, Thibault P, Van Eyk JE, Mak AS. Phosphorylation of caldesmon by p21-activated kinase. Implications for the Ca2+ sensitivity of smooth muscle contraction Journal of Biological Chemistry. 275: 1959-1965. PMID 10636898 DOI: 10.1074/Jbc.275.3.1959  0.591
1999 Foster DB, Van Eyk JE. In search of the proteins that cause myocardial stunning Circulation Research. 85: 470-472. PMID 10473676  0.602
1999 McDonough JL, Arrell DK, Van Eyk JE. Troponin I degradation and covalent complex formation accompanies myocardial ischemia/reperfusion injury Circulation Research. 84: 9-20. PMID 9915770  0.712
1998 Van Eyk JE, Arrell DK, Foster DB, Strauss JD, Heinonen TY, Furmaniak-Kazmierczak E, Côté GP, Mak AS. Different molecular mechanisms for Rho family GTPase-dependent, Ca2+-independent contraction of smooth muscle. The Journal of Biological Chemistry. 273: 23433-9. PMID 9722579 DOI: 10.1074/jbc.273.36.23433  0.77
1998 Van Eyk JE, Powers F, Law W, Larue C, Hodges RS, Solaro RJ. Breakdown and release of myofilament proteins during ischemia and ischemia/reperfusion in rat hearts: identification of degradation products and effects on the pCa-force relation. Circulation Research. 82: 261-71. PMID 9468197 DOI: 10.1161/01.Res.82.2.261  0.499
1997 Tripet B, Van Eyk JE, Hodges RS. Mapping of a second actin-tropomyosin and a second troponin C binding site within the C terminus of troponin I, and their importance in the Ca2+-dependent regulation of muscle contraction. Journal of Molecular Biology. 271: 728-50. PMID 9299323 DOI: 10.1006/Jmbi.1997.1200  0.445
1997 Van Eyk JE, Thomas LT, Tripet B, Wiesner RJ, Pearlstone JR, Farah CS, Reinach FC, Hodges RS. Distinct regions of troponin I regulate Ca2+-dependent activation and Ca2+ sensitivity of the acto-S1-TM ATPase activity of the thin filament. The Journal of Biological Chemistry. 272: 10529-37. PMID 9099697 DOI: 10.1074/Jbc.272.16.10529  0.426
1995 Van Eyk JE, Caday-Malcolm RA, Yu L, Irvin RT, Hodges RS. Anti-peptide monoclonal antibody imaging of a common binding domain involved in muscle regulation Protein Science. 4: 781-790. PMID 7613476 DOI: 10.1002/Pro.5560040418  0.439
1993 Van Eyk JE, Strauss JD, Hodges RS, Rüegg JC. A synthetic peptide mimics troponin I function in the calcium-dependent regulation of muscle contraction. Febs Letters. 323: 223-8. PMID 8500614 DOI: 10.1016/0014-5793(93)81344-Y  0.455
1993 Van Eyk JE, Hodges RS. The Use of Synthetic Peptides to Unravel the Mechanism of Muscle Regulation Methods. 5: 264-280. DOI: 10.1006/Meth.1993.1033  0.464
1992 Campbell AP, Van Eyk JE, Hodges RS, Sykes BD. Interaction of troponin I and troponin C: use of the two-dimensional transferred nuclear Overhauser effect to determine the structure of a Gly-110 inhibitory troponin I peptide analog when bound to cardiac troponin C. Biochimica Et Biophysica Acta. 1160: 35-54. PMID 1420332 DOI: 10.1016/0167-4838(92)90036-D  0.455
1992 Sönnichsen FD, Van Eyk JE, Hodges RS, Sykes BD. Effect of trifluoroethanol on protein secondary structure: an NMR and CD study using a synthetic actin peptide. Biochemistry. 31: 8790-8. PMID 1390666 DOI: 10.1021/Bi00152A015  0.407
1991 Van Eyk JE, Kay CM, Hodges RS. A comparative study of the interactions of synthetic peptides of the skeletal and cardiac troponin I inhibitory region with skeletal and cardiac troponin C. Biochemistry. 30: 9974-81. PMID 1911788 DOI: 10.1021/Bi00105A023  0.472
1991 Van Eyk JE, Hodges RS. A synthetic peptide of the N-terminus of actin interacts with myosin. Biochemistry. 30: 11676-82. PMID 1836353 DOI: 10.1021/Bi00114A010  0.418
1989 Rüegg JC, Zeugner C, Van Eyk J, Kay CM, Hodges RS. Inhibition of TnI-TnC interaction and contraction of skinned muscle fibres by the synthetic peptide TnI [104-115]. PflüGers Archiv : European Journal of Physiology. 414: 430-6. PMID 2798040 DOI: 10.1007/Bf00585053  0.442
1988 Van Eyk JE, Hodges RS. The biological importance of each amino acid residue of the troponin I inhibitory sequence 104-115 in the interaction with troponin C and tropomyosin-actin. The Journal of Biological Chemistry. 263: 1726-32. PMID 3338991  0.415
1987 Van Eyk JE, Hodges RS. Calmodulin and troponin C: affinity chromatographic study of divalent cation requirements for troponin I inhibitory peptide (residues 104-115), mastoparan and fluphenazine binding. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 65: 982-8. PMID 3442631 DOI: 10.1139/O87-128  0.438
1986 Cachia PJ, Van Eyk J, Ingraham RH, McCubbin WD, Kay CM, Hodges RS. Calmodulin and troponin C: a comparative study of the interaction of mastoparan and troponin I inhibitory peptide [104-115]. Biochemistry. 25: 3553-62. PMID 2941074 DOI: 10.1021/Bi00360A013  0.435
1986 Van Eyk JE, Cachia PJ, Ingraham RH, Hodges RS. Studies on the regulatory complex of rabbit skeletal muscle: Contributions of troponin subunits and tropomyosin in the presence and absence of Mg2+ to the acto-S1 ATPase activity Journal of Protein Chemistry. 5: 335-354. DOI: 10.1007/Bf01025962  0.401
1985 Cachia PJ, Van Eyk J, McCubbin WD, Kay CM, Hodges RS. Ion-exchange high-performance liquid chromatographic purification of bovine cardiac and rabbit skeletal muscle troponin subunits. Journal of Chromatography. 343: 315-28. PMID 4066873 DOI: 10.1016/S0378-4347(00)84600-9  0.417
1983 Cachia PJ, van Eyk J, Chong PC, Taneja A, Hodges RS. Separation of basic peptides by cation-exchange high-performance liquid chromatography Journal of Chromatography A. 266: 651-659. DOI: 10.1016/S0021-9673(01)90935-5  0.377
Low-probability matches (unlikely to be authored by this person)
2010 Stastna M, Chimenti I, Marbán E, Van Eyk JE. Identification and functionality of proteomes secreted by rat cardiac stem cells and neonatal cardiomyocytes. Proteomics. 10: 245-53. PMID 20014349 DOI: 10.1002/pmic.200900515  0.294
2024 Karpov OA, Stotland A, Raedschelders K, Chazarin B, Ai L, Murray CI, Van Eyk JE. Proteomics of the Heart. Physiological Reviews. PMID 38300522 DOI: 10.1152/physrev.00026.2023  0.293
2014 Kooij V, Venkatraman V, Kirk JA, Ubaida-Mohien C, Graham DR, Faber MJ, Van Eyk JE. Identification of cardiac myofilament protein isoforms using multiple mass spectrometry based approaches. Proteomics. Clinical Applications. 8: 578-589. PMID 24974818 DOI: 10.1002/Prca.201400039  0.291
2007 White MY, Van Eyk JE. Cardiovascular proteomics: past, present, and future. Molecular Diagnosis & Therapy. 11: 83-95. PMID 17397244 DOI: 10.1007/BF03256227  0.286
2021 de Freitas Germano J, Sharma A, Stastna M, Huang C, Aniag M, Aceves A, Van Eyk JE, Mentzer RM, Piplani H, Andres AM, Gottlieb RA. Proteomics of Mouse Heart Ventricles Reveals Mitochondria and Metabolism as Major Targets of a Post-Infarction Short-Acting GLP1Ra-Therapy. International Journal of Molecular Sciences. 22. PMID 34445425 DOI: 10.3390/ijms22168711  0.285
2021 Soetkamp D, Gallet R, Parker SJ, Holewinski R, Venkatraman V, Peck K, Goldhaber JI, Marban E, Van Eyk JE. Myofilament Phosphorylation in Stem Cell Treated Diastolic Heart Failure. Circulation Research. PMID 34641704 DOI: 10.1161/CIRCRESAHA.119.316311  0.284
2013 Kooij V, Zhang P, Piersma SR, Sequeira V, Boontje NM, Wijnker PJ, Jiménez CR, Jaquet KE, dos Remedios C, Murphy AM, Van Eyk JE, van der Velden J, Stienen GJ. PKCα-specific phosphorylation of the troponin complex in human myocardium: a functional and proteomics analysis. Plos One. 8: e74847. PMID 24116014 DOI: 10.1371/journal.pone.0074847  0.284
2017 Chung HS, Kim GE, Holewinski RJ, Venkatraman V, Zhu G, Bedja D, Kass DA, Van Eyk JE. Transient receptor potential channel 6 regulates abnormal cardiac S-nitrosylation in Duchenne muscular dystrophy. Proceedings of the National Academy of Sciences of the United States of America. 114: E10763-E10771. PMID 29187535 DOI: 10.1073/pnas.1712623114  0.282
2020 Ranek MJ, Oeing C, Sanchez-Hodge R, Kokkonen-Simon KM, Dillard D, Aslam MI, Rainer PP, Mishra S, Dunkerly-Eyring B, Holewinski RJ, Virus C, Zhang H, Mannion MM, Agrawal V, Hahn V, ... ... Van Eyk JE, et al. CHIP phosphorylation by protein kinase G enhances protein quality control and attenuates cardiac ischemic injury. Nature Communications. 11: 5237. PMID 33082318 DOI: 10.1038/s41467-020-18980-x  0.279
2002 McDonough JL, Neverova I, Van Eyk JE. Proteomic analysis of human biopsy samples by single two-dimensional electrophoresis: Coomassie, silver, mass spectrometry, and Western blotting. Proteomics. 2: 978-87. PMID 12203893 DOI: 10.1002/1615-9861(200208)2:8<978::AID-PROT978>3.0.CO;2-3  0.278
2001 Van Eyk JE. Proteomics: unraveling the complexity of heart disease and striving to change cardiology. Current Opinion in Molecular Therapeutics. 3: 546-53. PMID 11804269  0.275
2017 Soetkamp D, Raedschelders K, Mastali M, Sobhani K, Bairey Merz CN, Van Eyk J. The continuing evolution of cardiac troponin I biomarker analysis: from protein to proteoform. Expert Review of Proteomics. 14: 973-986. PMID 28984473 DOI: 10.1080/14789450.2017.1387054  0.273
2011 Stanley BA, Graham DR, James J, Mitsak M, Tarwater PM, Robbins J, Van Eyk JE. Altered myofilament stoichiometry in response to heart failure in a cardioprotective α-myosin heavy chain transgenic rabbit model. Proteomics. Clinical Applications. 5: 147-58. PMID 21365772 DOI: 10.1002/prca.201000116  0.271
2016 Kooij V, Viswanathan MC, Lee DI, Rainer PP, Schmidt W, Kronert WA, Harding SE, Kass DA, Bernstein SI, Van Eyk JE, Cammarato A. Profilin modulates sarcomeric organization and mediates cardiomyocyte hypertrophy. Cardiovascular Research. 110: 238-48. PMID 26956799 DOI: 10.1093/Cvr/Cvw050  0.271
2006 Sheng S, Chen D, Van Eyk JE. Multidimensional liquid chromatography separation of intact proteins by chromatographic focusing and reversed phase of the human serum proteome: optimization and protein database. Molecular & Cellular Proteomics : McP. 5: 26-34. PMID 16188874 DOI: 10.1074/mcp.T500019-MCP200  0.271
2003 Stanley BA, Neverova I, Brown HA, Van Eyk JE. Optimizing protein solubility for two-dimensional gel electrophoresis analysis of human myocardium. Proteomics. 3: 815-20. PMID 12833503 DOI: 10.1002/pmic.200300388  0.27
2015 Fert-Bober J, Giles JT, Holewinski RJ, Kirk JA, Uhrigshardt H, Crowgey EL, Andrade F, Bingham CO, Park JK, Halushka MK, Kass DA, Bathon JM, Van Eyk JE. Citrullination of myofilament proteins in heart failure. Cardiovascular Research. 108: 232-42. PMID 26113265 DOI: 10.1093/Cvr/Cvv185  0.268
2006 Arab S, Gramolini AO, Ping P, Kislinger T, Stanley B, van Eyk J, Ouzounian M, MacLennan DH, Emili A, Liu PP. Cardiovascular proteomics: tools to develop novel biomarkers and potential applications. Journal of the American College of Cardiology. 48: 1733-41. PMID 17084242 DOI: 10.1016/J.Jacc.2006.06.063  0.267
2001 Van Eyk JE, Murphy AM. The role of troponin abnormalities as a cause for stunned myocardium Coronary Artery Disease. 12: 343-347. PMID 11491198 DOI: 10.1097/00019501-200108000-00002  0.264
2000 Murphy AM, Kögler H, Georgakopoulos D, McDonough JL, Kass DA, Van Eyk JE, Marbán E. Transgenic mouse model of stunned myocardium. Science (New York, N.Y.). 287: 488-91. PMID 10642551 DOI: 10.1126/Science.287.5452.488  0.263
1996 Solaro RJ, Van Eyk J. Altered interactions among thin filament proteins modulate cardiac function Journal of Molecular and Cellular Cardiology. 28: 217-230. PMID 8729055 DOI: 10.1006/jmcc.1996.0021  0.263
2011 Kooij V, Piersma SR, Zhang P, Boontje NM, Jiménez CR, Jaquet K, dos Remedios C, Murphy A, van Eyk J, van der Velden J, Stienen GJ. Protein Kinase Cα Mediated Phosphorylation of Cardiac Troponin Reduces Maximal Force and Exerts Dual Effects on Ca2+-Sensitivity in Human Cardiomyocytes Biophysical Journal. 100: 371a. DOI: 10.1016/j.bpj.2010.12.2210  0.263
2002 Neverova I, Van Eyk JE. Application of reversed phase high performance liquid chromatography for subproteomic analysis of cardiac muscle. Proteomics. 2: 22-31. PMID 11788988 DOI: 10.1002/1615-9861(200201)2:1<22::AID-PROT22>3.0.CO;2-L  0.261
2015 Yang S, Chen L, Sun S, Shah P, Yang W, Zhang B, Zhang Z, Chan DW, Kass DA, van Eyk JE, Zhang H. Glycoproteins identified from heart failure and treatment models. Proteomics. 15: 567-79. PMID 25141849 DOI: 10.1002/Pmic.201400151  0.26
2018 Aebersold R, Agar JN, Amster IJ, Baker MS, Bertozzi CR, Boja ES, Costello CE, Cravatt BF, Fenselau C, Garcia BA, Ge Y, Gunawardena J, Hendrickson RC, Hergenrother PJ, Huber CG, ... Van Eyk JE, et al. How many human proteoforms are there? Nature Chemical Biology. 14: 206-214. PMID 29443976 DOI: 10.1038/Nchembio.2576  0.26
2014 Kooij V, Venkatraman V, Tra J, Kirk JA, Rowell J, Blice-Baum A, Cammarato A, Van Eyk JE. Sizing up models of heart failure: Proteomics from flies to humans. Proteomics. Clinical Applications. 8: 653-64. PMID 24723306 DOI: 10.1002/Prca.201300123  0.256
2019 Omenn GS, Lane L, Overall CM, Corrales FJ, Schwenk JM, Paik YK, Van Eyk JE, Liu S, Pennington S, Snyder MP, Baker MS, Deutsch EW. Progress on Identifying and Characterizing the Human Proteome: 2018-2019 Metrics from the HUPO Human Proteome Project. Journal of Proteome Research. PMID 31430157 DOI: 10.1021/Acs.Jproteome.9B00434  0.255
2015 Lam MP, Venkatraman V, Cao Q, Wang D, Dincer TU, Lau E, Su AI, Xing Y, Ge J, Ping P, Van Eyk JE. Prioritizing Proteomics Assay Development for Clinical Translation. Journal of the American College of Cardiology. 66: 202-4. PMID 26160638 DOI: 10.1016/J.Jacc.2015.04.072  0.255
2009 Williams LM, Fu Z, Dulloor P, Savage WJ, Barron-Casella E, Strouse JJ, DeBaun MR, Van Eyk J, Everett A, Casella JF. Proteomic-Based Approach for Biomarker Discovery to Predict Silent Cerebral Infarct in Patients with Sickle Cell Disease. Blood. 114: 2579-2579. DOI: 10.1182/Blood.V114.22.2579.2579  0.255
2018 Stachowski MJ, Holewinski RJ, Grote E, Venkatraman V, Van Eyk JE, Kirk JA. Phospho-Proteomic Analysis of Cardiac Dyssynchrony and Resynchronization Therapy. Proteomics. 18: e1800079. PMID 30129105 DOI: 10.1002/Pmic.201800079  0.254
2012 Stastna M, Van Eyk JE. Analysis of protein isoforms: can we do it better? Proteomics. 12: 2937-48. PMID 22888084 DOI: 10.1002/pmic.201200161  0.253
2024 Omenn GS, Lane L, Overall CM, Lindskog C, Pineau C, Packer NH, Cristea IM, Weintraub ST, Orchard S, Roehrl MHA, Nice E, Guo T, Van Eyk JE, Liu S, Bandeira N, et al. The 2023 Report on the Proteome from the HUPO Human Proteome Project. Journal of Proteome Research. PMID 38232391 DOI: 10.1021/acs.jproteome.3c00591  0.252
2010 Kooij V, Piersma SR, Tang KW, Jiménez CR, Zang P, van Eyk JE, Murphy AM, van der Velden J, Stienen GJ. Identification of Unknown Protein Kinase Cα Phosphorylation Sites on Both Human Cardiac Troponin I and T Biophysical Journal. 98: 358a. DOI: 10.1016/j.bpj.2009.12.1931  0.251
2020 Omenn GS, Lane L, Overall CM, Cristea IM, Corrales FJ, Lindskog C, Paik YK, Van Eyk JE, Liu S, Pennington S, Snyder MP, Baker MS, Bandeira N, Aebersold R, Moritz RL, et al. Research on The Human Proteome Reaches a Major Milestone: >90% of Predicted Human Proteins Now Credibly Detected, according to the HUPO Human Proteome Project. Journal of Proteome Research. PMID 32931287 DOI: 10.1021/Acs.Jproteome.0C00485  0.25
2017 Stastna M, Gottlieb RA, Van Eyk JE. Exploring ribosome composition and newly synthesized proteins through proteomics and potential biomedical applications. Expert Review of Proteomics. 14: 529-543. PMID 28532181 DOI: 10.1080/14789450.2017.1333424  0.249
2019 Ranek MJ, Kokkonen-Simon KM, Chen A, Dunkerly-Eyring BL, Vera MP, Oeing CU, Patel CH, Nakamura T, Zhu G, Bedja D, Sasaki M, Holewinski RJ, Van Eyk JE, Powell JD, Lee DI, et al. PKG1-modified TSC2 regulates mTORC1 activity to counter adverse cardiac stress. Nature. PMID 30700906 DOI: 10.1038/s41586-019-0895-y  0.248
2018 Omenn GS, Lane L, Overall CM, Corrales FJ, Schwenk JM, Paik YK, Van Eyk JE, Liu S, Snyder M, Baker MS, Deutsch EW. Progress on Identifying and Characterizing the Human Proteome: 2018 Metrics from the HUPO Human Proteome Project. Journal of Proteome Research. PMID 30099871 DOI: 10.1021/Acs.Jproteome.8B00441  0.247
2011 Tocchetti CG, Stanley BA, Murray CI, Sivakumaran V, Donzelli S, Mancardi D, Pagliaro P, Gao WD, van Eyk J, Kass DA, Wink DA, Paolocci N. Playing with cardiac "redox switches": the "HNO way" to modulate cardiac function. Antioxidants & Redox Signaling. 14: 1687-98. PMID 21235349 DOI: 10.1089/Ars.2010.3859  0.245
2015 Stastna M, Van Eyk JE. Posttranslational modifications of lysine and evolving role in heart pathologies-recent developments. Proteomics. 15: 1164-80. PMID 25430483 DOI: 10.1002/pmic.201400312  0.245
2003 Dos Remedios CG, Liew CC, Allen PD, Winslow RL, Van Eyk JE, Dunn MJ. Genomics, proteomics and bioinformatics of human heart failure. Journal of Muscle Research and Cell Motility. 24: 251-60. PMID 14620738 DOI: 10.1023/A:1025433721505  0.242
2019 Vadakke-Madathil S, LaRocca G, Raedschelders K, Yoon J, Parker SJ, Tripodi J, Najfeld V, Van Eyk JE, Chaudhry HW. Multipotent fetal-derived Cdx2 cells from placenta regenerate the heart. Proceedings of the National Academy of Sciences of the United States of America. PMID 31109997 DOI: 10.1073/pnas.1811827116  0.242
2008 Agnetti G, Bezstarosti K, Dekkers DHW, Verhoeven AJM, Giordano E, Guarnieri C, Caldarera CM, Van Eyk JE, Lamers JMJ. Proteomic profiling of endothelin-1-stimulated hypertrophic cardiomyocytes reveals the increase of four different desmin species and α-B-crystallin Biochimica Et Biophysica Acta - Proteins and Proteomics. 1784: 1068-1076. PMID 18472024 DOI: 10.1016/j.bbapap.2008.04.003  0.241
2007 Kane LA, Neverova I, Van Eyk JE. Subfractionation of heart tissue: the "in sequence" myofilament protein extraction of myocardial tissue. Methods in Molecular Biology (Clifton, N.J.). 357: 87-90. PMID 17172681 DOI: 10.1385/1-59745-214-9:87  0.24
2007 Stastna M, Behrens A, Noguera G, Herretes S, McDonnell P, Van Eyk JE. Proteomics of the aqueous humor in healthy New Zealand rabbits. Proteomics. 7: 4358-75. PMID 18040985 DOI: 10.1002/pmic.200700300  0.24
2013 Murray CI, Chung HS, Uhrigshardt H, Van Eyk JE. Quantification of mitochondrial S-nitrosylation by CysTMT⁶ switch assay. Methods in Molecular Biology (Clifton, N.J.). 1005: 169-79. PMID 23606257 DOI: 10.1007/978-1-62703-386-2_14  0.24
2016 Kirk JA, Holewinski RJ, Crowgey EL, Van Eyk JE. Protein kinase G signaling in cardiac pathophysiology: Impact of proteomics on clinical trials. Proteomics. 16: 894-905. PMID 26670943 DOI: 10.1002/Pmic.201500401  0.239
2013 Stastna M, Van Eyk JE. Optimized method for identification of the proteomes secreted by cardiac cells. Methods in Molecular Biology (Clifton, N.J.). 1005: 225-35. PMID 23606261 DOI: 10.1007/978-1-62703-386-2_18  0.238
2016 Lam MP, Venkatraman V, Xing Y, Lau E, Cao Q, Ng DC, Su AI, Ge J, Van Eyk JE, Ping P. Data-Driven Approach To Determine Popular Proteins for Targeted Proteomics Translation of Six Organ Systems. Journal of Proteome Research. 15: 4126-4134. PMID 27356587 DOI: 10.1021/Acs.Jproteome.6B00095  0.237
2015 Kirk JA, Holewinski RJ, Venkatraman V, Grote E, Kass DA, Van Eyk JE. Mass Spectrometry-Based Analysis of the Phospho-Proteome for Cardiac Dyssynchrony and Resynchronization Therapy Biophysical Journal. 108: 273a. DOI: 10.1016/J.Bpj.2014.11.1497  0.236
2021 Van Eyk JE. The World of Protein Interactions: Defining the Caveolin 3 Cardiac Interactome. Circulation Research. 128: 720-722. PMID 33734816 DOI: 10.1161/CIRCRESAHA.121.318922  0.236
2011 White MY, Brown DA, Sheng S, Cole RN, O'Rourke B, Van Eyk JE. Parallel proteomics to improve coverage and confidence in the partially annotated Oryctolagus cuniculus mitochondrial proteome. Molecular & Cellular Proteomics : McP. 10: M110.004291. PMID 21036924 DOI: 10.1074/mcp.M110.004291  0.235
2018 Janssens JV, Ma B, Brimble MA, Van Eyk JE, Delbridge LMD, Mellor KM. Cardiac troponins may be irreversibly modified by glycation: novel potential mechanisms of cardiac performance modulation. Scientific Reports. 8: 16084. PMID 30382112 DOI: 10.1038/S41598-018-33886-X  0.234
2013 Kooij V, Holewinski RJ, Murphy AM, Van Eyk JE. Characterization of the cardiac myosin binding protein-C phosphoproteome in healthy and failing human hearts. Journal of Molecular and Cellular Cardiology. 60: 116-20. PMID 23619294 DOI: 10.1016/j.yjmcc.2013.04.012  0.233
2009 Stastna M, Abraham MR, Van Eyk JE. Cardiac stem/progenitor cells, secreted proteins, and proteomics. Febs Letters. 583: 1800-7. PMID 19303873 DOI: 10.1016/j.febslet.2009.03.026  0.232
2017 Sessions AO, Kaushik G, Parker S, Raedschelders K, Bodmer R, Van Eyk JE, Engler AJ. Extracellular matrix downregulation in the Drosophila heart preserves contractile function and improves lifespan. Matrix Biology : Journal of the International Society For Matrix Biology. 62: 15-27. PMID 27793636 DOI: 10.1016/J.Matbio.2016.10.008  0.232
2012 Zhang P, Kirk JA, Ji W, dos Remedios CG, Kass DA, Van Eyk JE, Murphy AM. Multiple reaction monitoring to identify site-specific troponin I phosphorylated residues in the failing human heart. Circulation. 126: 1828-37. PMID 22972900 DOI: 10.1161/Circulationaha.112.096388  0.232
2012 Kooij V, Ji W, Wang S, dos Remedios C, Murphy AM, Van Eyk JE. Novel Phosphorylation Sites and Reduced Phosphorylation Levels in Human Cardiac MyBP-C from Failing Hearts Biophysical Journal. 102: 557a-558a. DOI: 10.1016/j.bpj.2011.11.3038  0.232
2020 Stotland AB, Spivia W, Orosco A, Andres AM, Gottlieb RA, Van Eyk JE, Parker SJ. MitoPlex: A targeted multiple reaction monitoring assay for quantification of a curated set of mitochondrial proteins. Journal of Molecular and Cellular Cardiology. 142: 1-13. PMID 32234390 DOI: 10.1016/J.Yjmcc.2020.03.011  0.23
2016 Kaushik G, Van Eyk J, Cammarato A, Engler A. Vinculin Remodeling of the Sarcomere Lattice Regulates Contractile Function Biophysical Journal. 110: 94a. DOI: 10.1016/J.Bpj.2015.11.567  0.229
2004 Elliott ST, Crider DG, Garham CP, Boheler KR, Van Eyk JE. Two-dimensional gel electrophoresis database of cultured murine R1 embryonic stem cells Proteomics. 4: 3813-3832. PMID 15378706 DOI: 10.1002/pmic.200300820  0.229
2008 Matt P, Fu Z, Fu Q, Van Eyk JE. Biomarker discovery: proteome fractionation and separation in biological samples. Physiological Genomics. 33: 12-7. PMID 18162500 DOI: 10.1152/physiolgenomics.00282.2007  0.229
2024 Ibrahim AGE, Ciullo A, Yamaguchi S, Li C, Antes T, Jones X, Li L, Murali R, Maslennikov I, Sundararaman N, Soetkamp D, Cingolani E, Van Eyk J, Marbán E. A novel micropeptide, Slitharin, exerts cardioprotective effects in myocardial infarction. Proteomics. Clinical Applications. e2300128. PMID 38444254 DOI: 10.1002/prca.202300128  0.227
2020 Robinson AE, Binek A, Venkatraman V, Searle BC, Holewinski RJ, Rosenberger G, Parker SJ, Basisty N, Xie X, Lund PJ, Saxena G, Mato JM, Garcia BA, Schilling B, Lu SC, ... Van Eyk JE, et al. Lysine and Arginine Protein Post-translational Modifications by Enhanced DIA Libraries: Quantification in Murine Liver Disease. Journal of Proteome Research. PMID 32966080 DOI: 10.1021/acs.jproteome.0c00685  0.227
2006 McDonald T, Sheng S, Stanley B, Chen D, Ko Y, Cole RN, Pedersen P, Van Eyk JE. Expanding the subproteome of the inner mitochondria using protein separation technologies: one- and two-dimensional liquid chromatography and two-dimensional gel electrophoresis. Molecular & Cellular Proteomics : McP. 5: 2392-411. PMID 17000643 DOI: 10.1074/Mcp.T500036-Mcp200  0.224
2015 Kaushik G, Spenlehauer A, Sessions AO, Trujillo AS, Fuhrmann A, Fu Z, Venkatraman V, Pohl D, Tuler J, Wang M, Lakatta EG, Ocorr K, Bodmer R, Bernstein SI, Van Eyk JE, et al. Vinculin network-mediated cytoskeletal remodeling regulates contractile function in the aging heart. Science Translational Medicine. 7: 292ra99. PMID 26084806 DOI: 10.1126/Scitranslmed.Aaa5843  0.224
2018 Fert-Bober J, Murray CI, Parker SJ, Van Eyk JE. Precision Profiling of the Cardiovascular Post-Translationally Modified Proteome: Where There Is a Will, There Is a Way. Circulation Research. 122: 1221-1237. PMID 29700069 DOI: 10.1161/Circresaha.118.310966  0.222
2023 Cerro-Chiang G, Ayres M, Rivas A, Romero T, Parker SJ, Mastali M, Elashoff D, Chen P, Van Eyk JE, Wolters PJ, Boin F, Zaman T. Protein biomarkers of disease progression in patients with systemic sclerosis associated interstitial lung disease. Scientific Reports. 13: 8645. PMID 37244972 DOI: 10.1038/s41598-023-35840-y  0.222
2011 Murray CI, Kane LA, Uhrigshardt H, Wang SB, Van Eyk JE. Site-mapping of in vitro S-nitrosation in cardiac mitochondria: implications for cardioprotection. Molecular & Cellular Proteomics : McP. 10: M110.004721. PMID 21036925 DOI: 10.1074/mcp.M110.004721  0.22
2022 Burnum-Johnson KE, Conrads TP, Drake RR, Herr AE, Iyengar R, Kelly RT, Lundberg E, MacCoss MJ, Naba A, Nolan GP, Pevzner PA, Rodland KD, Sechi S, Slavov N, Spraggins JM, ... Van Eyk JE, et al. New views of old proteins: clarifying the enigmatic proteome. Molecular & Cellular Proteomics : McP. 100254. PMID 35654359 DOI: 10.1016/j.mcpro.2022.100254  0.22
2023 Ai L, Binek A, Kreimer S, Ayres M, Stotland A, Van Eyk JE. High-Field Asymmetric Waveform Ion Mobility Spectrometry: Practical Alternative for Cardiac Proteome Sample Processing. Journal of Proteome Research. PMID 37040897 DOI: 10.1021/acs.jproteome.3c00027  0.219
2010 Lin Y, Fu Q, Zhu J, Miller JM, Van Eyk JE. Development of a qualitative sequential immunoassay for characterizing the intrinsic properties of circulating cardiac troponin I. Clinical Chemistry. 56: 1307-19. PMID 20558636 DOI: 10.1373/clinchem.2009.135186  0.219
2007 Fu Q, Bovenkamp DE, Van Eyk JE. A rapid, economical, and reproducible method for human serum delipidation and albumin and IgG removal for proteomic analysis. Methods in Molecular Biology (Clifton, N.J.). 357: 365-71. PMID 17172702 DOI: 10.1385/1-59745-214-9:365  0.216
2008 White MY, Edwards AV, Cordwell SJ, Van Eyk JE. Mitochondria: A mirror into cellular dysfunction in heart disease. Proteomics. Clinical Applications. 2: 845-61. PMID 21136884 DOI: 10.1002/prca.200780135  0.215
2015 Lee DI, Zhu G, Sasaki T, Cho GS, Hamdani N, Holewinski R, Jo SH, Danner T, Zhang M, Rainer PP, Bedja D, Kirk JA, Ranek MJ, Dostmann WR, Kwon C, ... Van Eyk JE, et al. Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease. Nature. 519: 472-6. PMID 25799991 DOI: 10.1038/Nature14332  0.215
1992 Strauss JD, Zeugner C, Van Eyk JE, Bletz C, Troschka M, Rüegg JC. Troponin replacement in permeabilized cardiac muscle. Reversible extraction of troponin I by incubation with vanadate. Febs Letters. 310: 229-34. PMID 1397278 DOI: 10.1016/0014-5793(92)81338-M  0.214
2016 Fu Q, Chen Z, Zhang S, Parker SJ, Fu Z, Tin A, Liu X, Van Eyk JE. Multiple and Selective Reaction Monitoring Using Triple Quadrupole Mass Spectrometer: Preclinical Large Cohort Analysis. Methods in Molecular Biology (Clifton, N.J.). 1410: 249-64. PMID 26867749 DOI: 10.1007/978-1-4939-3524-6_15  0.213
2013 Grote E, Fu Q, Ji W, Liu X, Van Eyk JE. Using pure protein to build a multiple reaction monitoring mass spectrometry assay for targeted detection and quantitation. Methods in Molecular Biology (Clifton, N.J.). 1005: 199-213. PMID 23606259 DOI: 10.1007/978-1-62703-386-2_16  0.212
2019 Fert-Bober J, Venkatraman V, Hunter CL, Liu R, Crowgey EL, Pandey R, Holewinski RJ, Stotland A, Berman BP, Van Eyk JE. Mapping citrullinated sites in multiple organs of mice using hyper-citrullinated library. Journal of Proteome Research. PMID 30990720 DOI: 10.1021/Acs.Jproteome.9B00118  0.212
2003 McDonald TG, Van Eyk JE. Mitochondrial proteomics. Undercover in the lipid bilayer. Basic Research in Cardiology. 98: 219-27. PMID 12835951 DOI: 10.1007/s00395-003-0417-8  0.212
2020 Parker SJ, Chen L, Spivia W, Saylor G, Mao C, Venkatraman V, Holewinski RJ, Mastali M, Pandey R, Athas G, Yu G, Fu Q, Troxlair D, Vander Heide R, Herrington D, ... Van Eyk JE, et al. Identification of Putative Early Atherosclerosis Biomarkers by Unsupervised Deconvolution of Heterogeneous Vascular Proteomes. Journal of Proteome Research. PMID 32202800 DOI: 10.1021/Acs.Jproteome.0C00118  0.211
2015 Srivastava V, Tchernyshyov I, Van Eyk J, Robinson DN. The Dynamic Interplay between Cleavage Furrow Proteins in Cellular Mechanoresponsiveness Biophysical Journal. 108: 563a. DOI: 10.1016/J.Bpj.2014.11.3084  0.211
2007 Stanley BA, Van Eyk JE. A solubility optimization protocol for two-dimensional gel electrophoresis of cardiac tissue. Methods in Molecular Biology (Clifton, N.J.). 357: 59-65. PMID 17172678 DOI: 10.1385/1-59745-214-9:59  0.209
2004 Colantonio DA, Van Eyk JE, Przyklenk K. Stunned peri-infarct canine myocardium is characterized by degradation of troponin T, not troponin I. Cardiovascular Research. 63: 217-25. PMID 15249179 DOI: 10.1016/J.Cardiores.2004.04.006  0.209
2020 van den Broek I, Mastali M, Mouapi K, Bystrom C, Bairey Merz CN, Van Eyk JE. Quality control and outlier detection of targeted mass spectrometry data from multiplex protein panels. Journal of Proteome Research. PMID 32270680 DOI: 10.1021/acs.jproteome.9b00854  0.209
2016 Kirk JA, Holewinski RJ, Crowgey EL, Van Eyk JE. Front cover: Protein kinase G signaling in cardiac pathophysiology: Impact of proteomics on clinical trials Proteomics. 16: NA-NA. DOI: 10.1002/Pmic.201670050  0.208
2000 Simpson JA, van Eyk JE, Iscoe S. Hypoxemia-induced modification of troponin I and T in canine diaphragm. Journal of Applied Physiology (Bethesda, Md. : 1985). 88: 753-60. PMID 10658047 DOI: 10.1152/jappl.2000.88.2.753  0.207
2020 Blackwood EA, Thuerauf DJ, Stastna M, Stephens H, Sand Z, Pentoney A, Azizi K, Jakobi T, Van Eyk JE, Katus HA, Glembotski CC, Doroudgar S. Proteomic analysis of the cardiac myocyte secretome reveals extracellular protective functions for the ER stress response. Journal of Molecular and Cellular Cardiology. PMID 32339566 DOI: 10.1016/J.Yjmcc.2020.04.012  0.207
2005 Colantonio DA, Dunkinson C, Bovenkamp DE, Van Eyk JE. Effective removal of albumin from serum. Proteomics. 5: 3831-5. PMID 16145708 DOI: 10.1002/Pmic.200401235  0.207
2018 La Favor JD, Fu Z, Venkatraman V, Bivalacqua TJ, Van Eyk JE, Burnett AL. Molecular Profile of Priapism Associated with Low Nitric Oxide Bioavailability. Journal of Proteome Research. 17: 1031-1040. PMID 29394072 DOI: 10.1021/Acs.Jproteome.7B00657  0.207
2010 Williams LM, Fu Z, Dulloor P, Yen T, Barron-Casella E, Savage W, Van Eyk JE, Casella JF, Everett A. Hemoglobin depletion from plasma: considerations for proteomic discovery in sickle cell disease and other hemolytic processes. Proteomics. Clinical Applications. 4: 926-30. PMID 21179892 DOI: 10.1002/Prca.201000054  0.204
2018 Chung HS, Murray CI, Van Eyk JE. A Proteomics Workflow for Dual Labeling Biotin Switch Assay to Detect and Quantify Protein S-Nitroylation. Methods in Molecular Biology (Clifton, N.J.). 1747: 89-101. PMID 29600453 DOI: 10.1007/978-1-4939-7695-9_8  0.204
2015 Zhang P, Dufresne C, Turner R, Ferri S, Venkatraman V, Karani R, Lutty GA, Van Eyk JE, Semba RD. The proteome of human retina. Proteomics. 15: 836-40. PMID 25407473 DOI: 10.1002/pmic.201400397  0.204
2007 Guo Y, Fu Z, Van Eyk JE. A proteomic primer for the clinician. Proceedings of the American Thoracic Society. 4: 9-17. PMID 17202286 DOI: 10.1513/pats.200608-156JG  0.203
2011 Sheng S, Skalnikova H, Meng A, Tra J, Fu Q, Everett A, Van Eyk J. Intact protein separation by one- and two-dimensional liquid chromatography for the comparative proteomic separation of partitioned serum or plasma. Methods in Molecular Biology (Clifton, N.J.). 728: 29-46. PMID 21468939 DOI: 10.1007/978-1-61779-068-3_2  0.203
2002 Stanley BA, Neverova I, Van Eyk JE. 01 Optimizing protein extraction for proteomic analysis of human myocardial tissue Journal of Molecular and Cellular Cardiology. 34: A7. DOI: 10.1016/S0022-2828(02)90094-5  0.202
2015 Li Y, Shah P, De Marzo AM, Van Eyk JE, Li Q, Chan DW, Zhang H. Identification of glycoproteins containing specific glycans using a lectin-chemical method. Analytical Chemistry. 87: 4683-7. PMID 25837443 DOI: 10.1021/ac504304v  0.202
2016 Van Eyk JE, Corrales FJ, Aebersold R, Cerciello F, Deutsch EW, Roncada P, Sanchez JC, Yamamoto T, Yang P, Zhang H, Omenn GS. Highlights of the Biology and Disease-driven Human Proteome Project, 2015-2016. Journal of Proteome Research. 15: 3979-3987. PMID 27573249 DOI: 10.1021/Acs.Jproteome.6B00444  0.2
2007 Stanley BA, Van Eyk JE. A method for the effective depletion of albumin from cellular extracts: application to human myocardium. Methods in Molecular Biology (Clifton, N.J.). 357: 67-70. PMID 17172679 DOI: 10.1385/1-59745-214-9:67  0.2
2005 Fu Q, Garnham CP, Elliott ST, Bovenkamp DE, Van Eyk JE. A robust, streamlined, and reproducible method for proteomic analysis of serum by delipidation, albumin and IgG depletion, and two-dimensional gel electrophoresis. Proteomics. 5: 2656-64. PMID 15924293 DOI: 10.1002/Pmic.200402048  0.2
2020 Shufelt CL, Kim A, Joung S, Barsky L, Arnold C, Cheng S, Dhawan S, Fuller G, Speier W, Lopez M, Mastali M, Mouapi K, van den Broek I, Wei J, Spiegel B, ... Van Eyk JE, et al. Biometric and Psychometric Remote Monitoring and Cardiovascular Risk Biomarkers in Ischemic Heart Disease. Journal of the American Heart Association. e016023. PMID 32896202 DOI: 10.1161/Jaha.120.016023  0.2
2005 Neverova I, Van Eyk JE. Role of chromatographic techniques in proteomic analysis. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 815: 51-63. PMID 15652798 DOI: 10.1016/j.jchromb.2004.11.009  0.199
2016 Bullen JW, Tchernyshyov I, Holewinski RJ, DeVine L, Wu F, Venkatraman V, Kass DL, Cole RN, Van Eyk J, Semenza GL. Protein kinase A-dependent phosphorylation stimulates the transcriptional activity of hypoxia-inducible factor 1. Science Signaling. 9: ra56. PMID 27245613 DOI: 10.1126/Scisignal.Aaf0583  0.199
2018 Kothari P, Srivastava V, Aggarwal V, Tchernyshyov I, Van Eyk JE, Ha T, Robinson DN. Contractility kits promote assembly of the mechanoresponsive cytoskeletal network. Journal of Cell Science. PMID 30559246 DOI: 10.1242/Jcs.226704  0.199
2005 Guo Y, Ma SF, Grigoryev D, Van Eyk J, Garcia JG. 1-DE MS and 2-D LC-MS analysis of the mouse bronchoalveolar lavage proteome. Proteomics. 5: 4608-24. PMID 16240291 DOI: 10.1002/pmic.200500052  0.198
2013 Jin Z, Fu Z, Yang J, Troncosco J, Everett AD, Van Eyk JE. Identification and characterization of citrulline-modified brain proteins by combining HCD and CID fragmentation. Proteomics. 13: 2682-91. PMID 23828821 DOI: 10.1002/pmic.201300064  0.198
2017 Paik YK, Overall CM, Deutsch EW, Van Eyk JE, Omenn GS. Progress and Future Direction of Chromosome-Centric Human Proteome Project. Journal of Proteome Research. 16: 4253-4258. PMID 29191025 DOI: 10.1021/Acs.Jproteome.7B00734  0.197
2024 Janssens JV, Raaijmakers AJA, Koutsifeli P, Weeks KL, Bell JR, Van Eyk JE, Curl CL, Mellor KM, Delbridge LMD. Mechanical loading reveals an intrinsic cardiomyocyte stiffness contribution to diastolic dysfunction in murine cardiometabolic disease. Biorxiv : the Preprint Server For Biology. PMID 38659933 DOI: 10.1101/2024.02.21.581448  0.197
2013 Holewinski RJ, Jin Z, Powell MJ, Maust MD, Van Eyk JE. A fast and reproducible method for albumin isolation and depletion from serum and cerebrospinal fluid. Proteomics. 13: 743-50. PMID 23300121 DOI: 10.1002/pmic.201200192  0.197
2022 Stachowicz A, Sundararaman N, Venkatraman V, Van Eyk J, Fert-Bober J. pH/Acetonitrile-Gradient Reversed-Phase Fractionation of Enriched Hyper-Citrullinated Library in Combination with LC-MS/MS Analysis for Confident Identification of Citrullinated Peptides. Methods in Molecular Biology (Clifton, N.J.). 2420: 107-126. PMID 34905169 DOI: 10.1007/978-1-0716-1936-0_9  0.197
2014 Kirk JA, Holewinski RJ, Kooij V, Agnetti G, Tunin RS, Witayavanitkul N, de Tombe PP, Gao WD, Van Eyk J, Kass DA. Cardiac resynchronization sensitizes the sarcomere to calcium by reactivating GSK-3β. The Journal of Clinical Investigation. 124: 129-38. PMID 24292707 DOI: 10.1172/Jci69253  0.197
2016 Taegtmeyer H, Young ME, Lopaschuk GD, Abel ED, Brunengraber H, Darley-Usmar V, Des Rosiers C, Gerszten R, Glatz JF, Griffin JL, Gropler RJ, Holzhuetter HG, Kizer JR, Lewandowski ED, Malloy CR, ... Van Eyk JE, et al. Assessing Cardiac Metabolism: A Scientific Statement From the American Heart Association. Circulation Research. 118: 1659-701. PMID 27012580 DOI: 10.1161/Res.0000000000000097  0.196
2007 White MY, Brown DA, Sheng S, O'Rourke B, Van Eyk JE. Alterations to mitochondrial proteins initiated during myocardial ischemic preconditioning Journal of Molecular and Cellular Cardiology. 42: S174. DOI: 10.1016/J.Yjmcc.2007.03.534  0.194
2020 Zhang S, Raedschelders K, Venkatraman V, Huang L, Holewinski RJ, Fu Q, Van Eyk JE. A dual workflow to improve the proteomic coverage in plasma using data-independent acquisition-MS. Journal of Proteome Research. PMID 32176508 DOI: 10.1021/acs.jproteome.9b00607  0.193
2012 Murray CI, Uhrigshardt H, O'Meally RN, Cole RN, Van Eyk JE. Identification and quantification of S-nitrosylation by cysteine reactive tandem mass tag switch assay. Molecular & Cellular Proteomics : McP. 11: M111.013441. PMID 22126794 DOI: 10.1074/mcp.M111.013441  0.192
2017 Mao C, Howard TD, Sullivan D, Fu Z, Yu G, Parker SJ, Will R, Vander Heide RS, Wang Y, Hixson J, Van Eyk J, Herrington DM. Bioinformatic Analysis of Coronary Disease Associated SNPs and Genes to Identify Proteins Potentially Involved in the Pathogenesis of Atherosclerosis. Journal of Proteomics and Genomics Research. 2: 1-12. PMID 29367937 DOI: 10.14302/issn.2326-0793.jpgr-17-1447  0.192
2013 Liu X, Jin Z, O'Brien R, Bathon J, Dietz HC, Grote E, Van Eyk JE. Constrained selected reaction monitoring: quantification of selected post-translational modifications and protein isoforms. Methods (San Diego, Calif.). 61: 304-12. PMID 23523700 DOI: 10.1016/J.Ymeth.2013.03.006  0.191
2016 Hoofnagle AN, Whiteaker JR, Carr SA, Kuhn E, Liu T, Massoni SA, Thomas SN, Townsend RR, Zimmerman LJ, Boja E, Chen J, Crimmins DL, Davies SR, Gao Y, Hiltke TR, ... Van Eyk JE, et al. Recommendations for the Generation, Quantification, Storage, and Handling of Peptides Used for Mass Spectrometry-Based Assays. Clinical Chemistry. 62: 48-69. PMID 26719571 DOI: 10.1373/Clinchem.2015.250563  0.191
2013 Wang SB, Murray CI, Chung HS, Van Eyk JE. Redox regulation of mitochondrial ATP synthase. Trends in Cardiovascular Medicine. 23: 14-8. PMID 23312134 DOI: 10.1016/j.tcm.2012.08.005  0.19
2010 Agnetti G, Kaludercic N, Kane LA, Elliott ST, Guo Y, Chakir K, Samantapudi D, Paolocci N, Tomaselli GF, Kass DA, Van Eyk JE. Modulation of mitochondrial proteome and improved mitochondrial function by biventricular pacing of dyssynchronous failing hearts. Circulation. Cardiovascular Genetics. 3: 78-87. PMID 20160199 DOI: 10.1161/CIRCGENETICS.109.871236  0.19
2009 Murray CI, Barrett M, Van Eyk JE. Assessment of ProteoExtract subcellular fractionation kit reveals limited and incomplete enrichment of nuclear subproteome from frozen liver and heart tissue. Proteomics. 9: 3934-8. PMID 19637233 DOI: 10.1002/pmic.200701170  0.189
2001 Kent Arrell D, Neverova I, van Eyk JE. Cardiomyocyte proteome 2-D gel database construction: Detection and identification of co-migrating proteins Journal of Molecular and Cellular Cardiology. 33: A4. DOI: 10.1016/S0022-2828(01)90013-6  0.189
2003 McFawn PK, Shen L, Vincent SG, Mak A, Van Eyk JE, Fisher JT. Calcium-independent contraction and sensitization of airway smooth muscle by p21-activated protein kinase American Journal of Physiology - Lung Cellular and Molecular Physiology. 284: L863-L870. PMID 12513968  0.189
2006 Fu Q, Van Eyk JE. Proteomics and heart disease: identifying biomarkers of clinical utility. Expert Review of Proteomics. 3: 237-49. PMID 16608436 DOI: 10.1586/14789450.3.2.237  0.188
2009 Kane LA, Van Eyk JE. Post-translational modifications of ATP synthase in the heart: biology and function. Journal of Bioenergetics and Biomembranes. 41: 145-50. PMID 19399597 DOI: 10.1007/s10863-009-9218-6  0.188
2012 Lancaster TS, Jefferson SJ, Hunter JC, Lopez V, Van Eyk JE, Lakatta EG, Korzick DH. Quantitative proteomic analysis reveals novel mitochondrial targets of estrogen deficiency in the aged female rat heart. Physiological Genomics. 44: 957-69. PMID 22930739 DOI: 10.1152/Physiolgenomics.00184.2011  0.188
2018 Lau E, Venkatraman V, Thomas CT, Wu JC, Van Eyk JE, Lam MPY. Identifying High-Priority Proteins Across the Human Diseasome Using Semantic Similarity. Journal of Proteome Research. PMID 30256117 DOI: 10.1021/Acs.Jproteome.8B00393  0.187
2018 Rainer PP, Dong P, Sorge M, Fert-Bober J, Holewinski RJ, Wang Y, Foss CA, An SS, Baracca A, Solaini G, Glabe CG, Pomper MG, Van Eyk JE, Tomaselli GF, Paolocci N, et al. Desmin Phosphorylation Triggers Preamyloid Oligomers Formation and Myocyte Dysfunction in Acquired Heart Failure. Circulation Research. 122: e75-e83. PMID 29483093 DOI: 10.1161/Circresaha.117.312082  0.187
2023 Ijichi T, Sundararaman N, Martin TG, Pandey R, Koronyo E, Kirk JA, Marbán E, Van Eyk JE, Fert-Bober J. Peptidyl arginine deiminase inhibition alleviates angiotensin II-induced fibrosis. American Journal of Translational Research. 15: 4558-4572. PMID 37560217  0.186
2020 Sundararaman N, Go J, Robinson AE, Mato JM, Lu SC, Van Eyk JE, Venkatraman V. PINE: An Automation Tool to Extract & Visualize Protein-Centric Functional Networks. Journal of the American Society For Mass Spectrometry. PMID 32463229 DOI: 10.1021/jasms.0c00032  0.186
2023 Huang T, Wang J, Stukalov A, Donovan MKR, Ferdosi S, Williamson L, Just S, Castro G, Cantrell LS, Elgierari E, Benz RW, Huang Y, Motamedchaboki K, Hakimi A, Arrey T, ... ... Van Eyk JE, et al. Protein Coronas on Functionalized Nanoparticles Enable Quantitative and Precise Large-Scale Deep Plasma Proteomics. Biorxiv : the Preprint Server For Biology. PMID 37693476 DOI: 10.1101/2023.08.28.555225  0.185
2001 Kim SJ, Kudej RK, Yatani A, Kim YK, Takagi G, Honda R, Colantonio DA, Van Eyk JE, Vatner DE, Rasmusson RL, Vatner SF. A novel mechanism for myocardial stunning involving impaired Ca(2+) handling. Circulation Research. 89: 831-7. PMID 11679414  0.185
2007 Ganesh SK, Sharma Y, Dayhoff J, Fales HM, Van Eyk J, Kickler TS, Billings EM, Nabel EG. Detection of venous thromboembolism by proteomic serum biomarkers. Plos One. 2: e544. PMID 17579716 DOI: 10.1371/journal.pone.0000544  0.185
2012 Malliaras K, Li TS, Luthringer D, Terrovitis J, Cheng K, Chakravarty T, Galang G, Zhang Y, Schoenhoff F, Van Eyk J, Marbán L, Marbán E. Safety and efficacy of allogeneic cell therapy in infarcted rats transplanted with mismatched cardiosphere-derived cells. Circulation. 125: 100-12. PMID 22086878 DOI: 10.1161/CIRCULATIONAHA.111.042598  0.184
2015 Kirk JA, Chakir K, Lee KH, Karst E, Holewinski RJ, Pironti G, Tunin RS, Pozios I, Abraham TP, de Tombe P, Rockman HA, Van Eyk JE, Craig R, Farazi TG, Kass DA. Pacemaker-induced transient asynchrony suppresses heart failure progression. Science Translational Medicine. 7: 319ra207. PMID 26702095 DOI: 10.1126/Scitranslmed.Aad2899  0.184
2006 Ji Y, Neverova I, Van Eyk JE, Bennett BM. Nitration of tyrosine 92 mediates the activation of rat microsomal glutathione S-transferase by peroxynitrite Journal of Biological Chemistry. 281: 1986-1991. PMID 16314419 DOI: 10.1074/jbc.M509480200  0.184
2020 Fu Q, Johnson CW, Wijayawardena BK, Kowalski MP, Kheradmand M, Van Eyk JE. A Plasma Sample Preparation for Mass Spectrometry using an Automated Workstation. Journal of Visualized Experiments : Jove. PMID 32391810 DOI: 10.3791/59842  0.184
2013 Fu Z, Yan K, Rosenberg A, Jin Z, Crain B, Athas G, Heide RS, Howard T, Everett AD, Herrington D, Van Eyk JE. Improved protein extraction and protein identification from archival formalin-fixed paraffin-embedded human aortas. Proteomics. Clinical Applications. 7: 217-24. PMID 23339088 DOI: 10.1002/Prca.201200064  0.183
2020 Vitorino R, Guedes S, Vitorino C, Ferreira R, Amado F, Van Eyk JE. Elucidating Citrullination by Mass Spectrometry and its role in Disease Pathogenesis. Journal of Proteome Research. PMID 32966086 DOI: 10.1021/acs.jproteome.0c00474  0.182
2022 Norby FL, Nakamura K, Fu Q, Venkatraman V, Sundararaman N, Mastali M, Reinier K, Salvucci A, Jui J, Van Eyk JE, Chugh SS. A Panel of Blood Biomarkers Unique to Sudden Cardiac Arrest. Heart Rhythm. PMID 36521734 DOI: 10.1016/j.hrthm.2022.12.014  0.182
2019 Deutsch EW, Lane L, Overall CM, Bandeira N, Baker MS, Pineau C, Moritz RL, Corrales F, Orchard S, Van Eyk JE, Paik YK, Weintraub ST, Vandenbrouck Y, Omenn GS. Human Proteome Project Mass Spectrometry Data Interpretation Guidelines 3.0. Journal of Proteome Research. PMID 31599596 DOI: 10.1021/Acs.Jproteome.9B00542  0.181
2018 Herrington DM, Mao C, Parker SJ, Fu Z, Yu G, Chen L, Venkatraman V, Fu Y, Wang Y, Howard TD, Jun G, Zhao CF, Liu Y, Saylor G, Spivia WR, ... Van Eyk JE, et al. Proteomic Architecture of Human Coronary and Aortic Atherosclerosis. Circulation. 137: 2741-2756. PMID 29915101 DOI: 10.1161/Circulationaha.118.034365  0.181
2002 Canton M, Neverova I, Menabò R, Trevisin DB, Di Lisa F, van Eyk J. Myofibrillar protein oxidation induced by post-ischemic reperfusion in isolated rat hearts Journal of Molecular and Cellular Cardiology. 34: A15. DOI: 10.1016/S0022-2828(02)90785-6  0.181
2023 Gatto L, Aebersold R, Cox J, Demichev V, Derks J, Emmott E, Franks AM, Ivanov AR, Kelly RT, Khoury L, Leduc A, MacCoss MJ, Nemes P, Perlman DH, Petelski AA, ... ... Van Eyk J, et al. Initial recommendations for performing, benchmarking and reporting single-cell proteomics experiments. Nature Methods. PMID 36864200 DOI: 10.1038/s41592-023-01785-3  0.18
2006 Yang CG, Granite SJ, Van Eyk JE, Winslow RL. MASCOT HTML and XML parser: an implementation of a novel object model for protein identification data. Proteomics. 6: 5688-93. PMID 17006878 DOI: 10.1002/Pmic.200600157  0.18
2015 Gong J, Yao Y, Zhang P, Udayasuryan B, Komissarova EV, Chen J, Sivaramakrishnan S, Van Eyk JE, Steinberg SF. The C2 Domain and Altered ATP-Binding Loop Phosphorylation at Ser³⁵⁹ Mediate the Redox-Dependent Increase in Protein Kinase C-δ Activity. Molecular and Cellular Biology. 35: 1727-40. PMID 25755284 DOI: 10.1128/Mcb.01436-14  0.18
2005 Graham DRM, Elliott ST, Van Eyk JE. Broad-based proteomic strategies: A practical guide to proteomics and functional screening Journal of Physiology. 563: 1-9. PMID 15611015 DOI: 10.1113/jphysiol.2004.080341  0.179
1993 Strauss JD, Barth Z, Van Eyk JE, Rüegg JC. Probing the Regulation of Contractility in Cardiac and Smooth Muscle Skinned Fibers with Synthetic Peptides Methods. 5: 281-290. DOI: 10.1006/meth.1993.1034  0.179
2004 Granger CB, Van Eyk JE, Mockrin SC, Anderson NL. National Heart, Lung, And Blood Institute Clinical Proteomics Working Group report. Circulation. 109: 1697-703. PMID 15078805 DOI: 10.1161/01.CIR.0000121563.47232.2A  0.178
2023 Sundararaman N, Bhat A, Venkatraman V, Binek A, Dwight Z, Ariyasinghe NR, Escopete S, Joung SY, Cheng S, Parker SJ, Fert-Bober J, Van Eyk JE. BIRCH: An Automated Workflow for Evaluation, Correction, and Visualization of Batch Effect in Bottom-Up Mass Spectrometry-Based Proteomics Data. Journal of Proteome Research. 22: 471-481. PMID 36695565 DOI: 10.1021/acs.jproteome.2c00671  0.177
2022 Dawkins JF, Ehdaie A, Rogers R, Soetkamp D, Valle J, Holm K, Sanchez L, Tremmel I, Nawaz A, Shehata M, Wang X, Prakosa A, Yu J, Van Eyk JE, Trayanova N, et al. Biological substrate modification suppresses ventricular arrhythmias in a porcine model of chronic ischaemic cardiomyopathy. European Heart Journal. PMID 35262692 DOI: 10.1093/eurheartj/ehac042  0.177
2016 Gong J, Holewinski RJ, Van Eyk JE, Steinberg SF. A novel phosphorylation site at Ser130 adjacent to the pseudosubstrate domain contributes to the activation of protein kinase C-δ. The Biochemical Journal. 473: 311-20. PMID 26546672 DOI: 10.1042/Bj20150812  0.177
2010 Dudek SM, Chiang ET, Camp SM, Guo Y, Zhao J, Brown ME, Singleton PA, Wang L, Desai A, Arce FT, Lal R, Van Eyk JE, Imam SZ, Garcia JG. Abl tyrosine kinase phosphorylates nonmuscle Myosin light chain kinase to regulate endothelial barrier function. Molecular Biology of the Cell. 21: 4042-56. PMID 20861316 DOI: 10.1091/mbc.E09-10-0876  0.176
2016 Fu Q, Grote E, Zhu J, Jelinek C, Köttgen A, Coresh J, Van Eyk JE. An Empirical Approach to Signature Peptide Choice for Selected Reaction Monitoring: Quantification of Uromodulin in Urine. Clinical Chemistry. 62: 198-207. PMID 26589548 DOI: 10.1373/Clinchem.2015.242495  0.176
2011 Fan C, Fu Z, Su Q, Angelini DJ, Van Eyk J, Johns RA. S100A11 mediates hypoxia-induced mitogenic factor (HIMF)-induced smooth muscle cell migration, vesicular exocytosis, and nuclear activation. Molecular & Cellular Proteomics : McP. 10: M110.000901. PMID 21139050 DOI: 10.1074/Mcp.M110.000901  0.175
2013 Semba RD, Enghild JJ, Venkatraman V, Dyrlund TF, Van Eyk JE. The Human Eye Proteome Project: perspectives on an emerging proteome. Proteomics. 13: 2500-11. PMID 23749747 DOI: 10.1002/pmic.201300075  0.174
2000 Lehman W, Hatch V, Korman V, Rosol M, Thomas L, Maytum R, Geeves MA, Van Eyk JE, Tobacman LS, Craig R. Tropomyosin and actin isoforms modulate the localization of tropomyosin strands on actin filaments. Journal of Molecular Biology. 302: 593-606. PMID 10986121 DOI: 10.1006/Jmbi.2000.4080  0.174
2009 Fu Z, Wang M, Gucek M, Zhang J, Wu J, Jiang L, Monticone RE, Khazan B, Telljohann R, Mattison J, Sheng S, Cole RN, Spinetti G, Pintus G, Liu L, ... ... Van Eyk JE, et al. Milk fat globule protein epidermal growth factor-8: a pivotal relay element within the angiotensin II and monocyte chemoattractant protein-1 signaling cascade mediating vascular smooth muscle cells invasion. Circulation Research. 104: 1337-46. PMID 19443842 DOI: 10.1161/Circresaha.108.187088  0.174
2013 Aebersold R, Bader GD, Edwards AM, van Eyk JE, Kussmann M, Qin J, Omenn GS. The biology/disease-driven human proteome project (B/D-HPP): enabling protein research for the life sciences community. Journal of Proteome Research. 12: 23-7. PMID 23259511 DOI: 10.1021/Pr301151M  0.173
1996 Strauss JD, Van Eyk JE, Barth Z, Kluwe L, Wiesner RJ, Maéda K, Rüegg JC. Recombinant troponin I substitution and calcium responsiveness in skinned cardiac muscle. PflüGers Archiv : European Journal of Physiology. 431: 853-62. PMID 8927501 DOI: 10.1007/BF02332169  0.173
2016 Parker SJ, Venkatraman V, Van Eyk JE. Effect of peptide assay library size and composition in targeted data-independent acquisition-MS analyses. Proteomics. 16: 2221-37. PMID 27432805 DOI: 10.1002/Pmic.201600007  0.173
2018 Stastna M, Thomas A, Germano J, Pourpirali S, Van Eyk JE, Gottlieb RA. Dynamic Proteomic and miRNA Analysis of Polysomes from Isolated Mouse Heart After Langendorff Perfusion. Journal of Visualized Experiments : Jove. PMID 30222143 DOI: 10.3791/58079  0.173
2015 Parker SJ, Raedschelders K, Van Eyk JE. Emerging proteomic technologies for elucidating context-dependent cellular signaling events: A big challenge of tiny proportions. Proteomics. 15: 1486-502. PMID 25545106 DOI: 10.1002/Pmic.201400448  0.172
2012 Stastna M, Van Eyk JE. Investigating the secretome: lessons about the cells that comprise the heart. Circulation. Cardiovascular Genetics. 5: o8-o18. PMID 22337932 DOI: 10.1161/CIRCGENETICS.111.960187  0.172
2019 Ruiz-Romero C, Lam MP, Nilsson P, Önnerfjord P, Utz PJ, Van Eyk JE, Venkatraman V, Fert-Bober J, Watt FE, Blanco FJ. Mining the proteome associated with rheumatic and autoimmune diseases. Journal of Proteome Research. PMID 31599600 DOI: 10.1021/Acs.Jproteome.9B00360  0.17
2016 Zhang P, Karani R, Turner RL, Dufresne C, Ferri S, Van Eyk JE, Semba RD. The proteome of normal human retrobulbar optic nerve and sclera. Proteomics. 16: 2592-2596. PMID 27538499 DOI: 10.1002/pmic.201600229  0.17
2012 Stastna M, Van Eyk JE. Secreted proteins as a fundamental source for biomarker discovery. Proteomics. 12: 722-35. PMID 22247067 DOI: 10.1002/pmic.201100346  0.17
2022 Quesada O, Elboudwarej O, Nelson MD, Al-Badri A, Mastali M, Wei J, Zarrabi B, Suppogu N, Aldiwani H, Mehta P, Shufelt C, Cook-Wiens G, Berman DS, Thomson LEJ, Handberg E, ... ... Van Eyk JE, et al. Ultra-high sensitivity cardiac troponin-I concentration and left ventricular structure and function in women with ischemia and no obstructive coronary artery disease. American Heart Journal Plus : Cardiology Research and Practice. 13. PMID 35784010 DOI: 10.1016/j.ahjo.2022.100115  0.169
2016 Zhang P, Kirby D, Dufresne C, Chen Y, Turner R, Ferri S, Edward DP, Van Eyk JE, Semba RD. Defining the proteome of human iris, ciliary body, retinal pigment epithelium, and choroid. Proteomics. 16: 1146-53. PMID 26834087 DOI: 10.1002/pmic.201500188  0.169
2017 Crowgey EL, Matlock A, Venkatraman V, Fert-Bober J, Van Eyk JE. Mapping Biological Networks from Quantitative Data-Independent Acquisition Mass Spectrometry: Data to Knowledge Pipelines. Methods in Molecular Biology (Clifton, N.J.). 1558: 395-413. PMID 28150249 DOI: 10.1007/978-1-4939-6783-4_19  0.168
2021 Ho AS, Robinson A, Shon W, Laury A, Raedschelders K, Venkatraman V, Holewinski R, Zhang Y, Shiao SL, Chen MM, Mallen-St Clair J, Lin DC, Zumsteg ZS, Van Eyk JE. Comparative Proteomic Analysis of HPV(+) Oropharyngeal Squamous Cell Carcinoma Recurrence. Journal of Proteome Research. PMID 34846153 DOI: 10.1021/acs.jproteome.1c00757  0.168
2013 Fu Z, Wang M, Everett A, Lakatta E, Van Eyk J. Can proteomics yield insight into aging aorta? Proteomics. Clinical Applications. 7: 477-89. PMID 23788441 DOI: 10.1002/prca.201200138  0.167
2023 Whelan SA, Hendricks N, Dwight ZL, Fu Q, Moradian A, Van Eyk JE, Mockus SM. Assessment of a 60-Biomarker Health Surveillance Panel (HSP) on Whole Blood from Remote Sampling Devices by Targeted LC/MRM-MS and Discovery DIA-MS Analysis. Analytical Chemistry. PMID 37389440 DOI: 10.1021/acs.analchem.3c01189  0.167
2016 Deutsch EW, Overall CM, Van Eyk JE, Baker MS, Paik YK, Weintraub ST, Lane L, Martens L, Vandenbrouck Y, Kusebauch U, Hancock WS, Hermjakob H, Aebersold R, Moritz RL, Omenn GS. Human Proteome Project Mass Spectrometry Data Interpretation Guidelines 2.1. Journal of Proteome Research. 15: 3961-3970. PMID 27490519 DOI: 10.1021/Acs.Jproteome.6B00392  0.167
2023 Kreimer S, Binek A, Chazarin B, Cho JH, Haghani A, Hutton A, Marbán E, Mastali M, Meyer JG, Mesquita T, Song Y, Van Eyk J, Parker S. High-Throughput Single-Cell Proteomic Analysis of Organ-Derived Heterogeneous Cell Populations by Nanoflow Dual-Trap Single-Column Liquid Chromatography. Analytical Chemistry. PMID 37289937 DOI: 10.1021/acs.analchem.3c00213  0.167
2018 Papadaki M, Holewinski RJ, Previs SB, Martin TG, Stachowski MJ, Li A, Blair CA, Moravec CS, Van Eyk JE, Campbell KS, Warshaw DM, Kirk JA. Diabetes with heart failure increases methylglyoxal modifications in the sarcomere, which inhibit function. Jci Insight. 3. PMID 30333300 DOI: 10.1016/J.Bpj.2018.11.645  0.167
2006 Madsen LH, Christensen G, Lund T, Serebruany VL, Granger CB, Hoen I, Grieg Z, Alexander JH, Jaffe AS, Van Eyk JE, Atar D. Time course of degradation of cardiac troponin I in patients with acute ST-elevation myocardial infarction: the ASSENT-2 troponin substudy. Circulation Research. 99: 1141-7. PMID 17038641 DOI: 10.1161/01.RES.0000249531.23654.e1  0.167
2006 Wilkins MR, Appel RD, Van Eyk JE, Chung MC, Görg A, Hecker M, Huber LA, Langen H, Link AJ, Paik YK, Patterson SD, Pennington SR, Rabilloud T, Simpson RJ, Weiss W, et al. Guidelines for the next 10 years of proteomics. Proteomics. 6: 4-8. PMID 16400714 DOI: 10.1002/Pmic.200500856  0.167
2014 Agnetti G, Halperin VL, Kirk JA, Chakir K, Guo Y, Lund L, Nicolini F, Gherli T, Guarnieri C, Caldarera CM, Tomaselli GF, Kass DA, Van Eyk JE. Desmin modifications associate with amyloid-like oligomers deposition in heart failure. Cardiovascular Research. 102: 24-34. PMID 24413773 DOI: 10.1093/Cvr/Cvu003  0.167
2010 Stein KM, Ellenbogen KA, Gold MR, Lemke B, Lozano IF, Mittal S, Spinale FG, Van Eyk JE, Waggoner AD, Meyer TE. SmartDelay determined AV optimization: a comparison of AV delay methods used in cardiac resynchronization therapy (SMART-AV): rationale and design. Pacing and Clinical Electrophysiology : Pace. 33: 54-63. PMID 19821938 DOI: 10.1111/J.1540-8159.2009.02581.X  0.166
2023 Kreimer S, Binek A, Chazarin B, Cho JH, Haghani A, Hutton A, Marb N E, Mastali M, Meyer JG, Ribiero Mesquita TR, Song Y, Van Eyk J, Parker S. High Throughput Single Cell Proteomic Analysis of Organ Derived Heterogeneous Cell Populations by Nanoflow Dual Trap Single Column Liquid Chromatography. Biorxiv : the Preprint Server For Biology. PMID 36711540 DOI: 10.1101/2023.01.06.522908  0.166
2015 Chung HS, Murray CI, Venkatraman V, Crowgey EL, Rainer PP, Cole RN, Bomgarden RD, Rogers JC, Balkan W, Hare JM, Kass DA, Van Eyk JE. Dual Labeling Biotin Switch Assay to Reduce Bias Derived From Different Cysteine Subpopulations: A Method to Maximize S-Nitrosylation Detection. Circulation Research. 117: 846-57. PMID 26338901 DOI: 10.1161/CIRCRESAHA.115.307336  0.166
2004 Canton M, Neverova I, Menabò R, Van Eyk J, Di Lisa F. Evidence of myofibrillar protein oxidation induced by postischemic reperfusion in isolated rat hearts. American Journal of Physiology. Heart and Circulatory Physiology. 286: H870-7. PMID 14766672 DOI: 10.1152/ajpheart.00714.2003  0.165
2015 Ping P, Gustafsson ÅB, Bers DM, Blatter LA, Cai H, Jahangir A, Kelly D, Muoio D, O'Rourke B, Rabinovitch P, Trayanova N, Van Eyk J, Weiss JN, Wong R, Schwartz Longacre L. Harnessing the Power of Integrated Mitochondrial Biology and Physiology: A Special Report on the NHLBI Mitochondria in Heart Diseases Initiative. Circulation Research. 117: 234-238. PMID 26185209 DOI: 10.1161/Circresaha.117.306693  0.164
2022 Kreimer S, Haghani A, Binek A, Hauspurg A, Seyedmohammad S, Rivas A, Momenzadeh A, Meyer JG, Raedschelders K, Van Eyk JE. Parallelization with Dual-Trap Single-Column Configuration Maximizes Throughput of Proteomic Analysis. Analytical Chemistry. PMID 36044770 DOI: 10.1021/acs.analchem.2c02609  0.163
2018 Stastna M, Thomas A, Venkatraman V, Gottlieb RA, Van Eyk JE. Abstract 295: Proteomic Profiling of Changes at Active Polysomes That Occur as a Response to Ischemic Injury and Reperfusion of the Heart Circulation Research. 123. DOI: 10.1161/res.123.suppl_1.295  0.163
2023 Clouthier KL, Taylor AC, Xuhuai J, Liu Y, Parker S, Van Eyk J, Reddy S. A Noninvasive Circulating Signature of Combined Right Ventricular Pressure and Volume Overload in Tetralogy of Fallot/Pulmonary Atresia/Major Aortopulmonary Collateral Arteries. World Journal For Pediatric & Congenital Heart Surgery. 21501351231213626. PMID 38128927 DOI: 10.1177/21501351231213626  0.163
2007 Sheng S, Fu Q, Chapman J, Van Eyk J, Feitelson J. Industrial Science: Biomarker Discovery from Plasma: Maximizing Proteomic Breath and Depth Using Protein Partitioning and Fractionation Followed by Shotgun Mass Spectrometry Clinical Immunology. 123: S185. DOI: 10.1016/j.clim.2007.03.173  0.162
2009 Savage WJ, Fu Z, Barron-Casella E, Dulloor P, Jennings J, Dackiw E, Jones K, Williams LM, Crain B, Barton BA, Van Eyk J, DeBaun MR, Casella JF, Everett A. Glial Fibrillary Acidic Protein as a Plasma Biomarker of Brain Injury in Children with Sickle Cell Disease. Blood. 114: 1512-1512. DOI: 10.1182/Blood.V114.22.1512.1512  0.162
2010 Fu Q, Schoenhoff FS, Savage WJ, Zhang P, Van Eyk JE. Multiplex assays for biomarker research and clinical application: translational science coming of age. Proteomics. Clinical Applications. 4: 271-84. PMID 21137048 DOI: 10.1002/prca.200900217  0.162
2011 Zheng L, Foley K, Huang L, Leubner A, Mo G, Olino K, Edil BH, Mizuma M, Sharma R, Le DT, Anders RA, Illei PB, Van Eyk JE, Maitra A, Laheru D, et al. Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer. Plos One. 6: e19390. PMID 21572519 DOI: 10.1371/Journal.Pone.0019390  0.161
2007 Guo Y, Singleton PA, Rowshan A, Gucek M, Cole RN, Graham DR, Van Eyk JE, Garcia JG. Quantitative proteomics analysis of human endothelial cell membrane rafts: evidence of MARCKS and MRP regulation in the sphingosine 1-phosphate-induced barrier enhancement. Molecular & Cellular Proteomics : McP. 6: 689-96. PMID 17210631 DOI: 10.1074/mcp.M600398-MCP200  0.16
2007 Matt P, Fu Z, Carrel T, Huso DL, Dirnhofer S, Lefkovits I, Zerkowski HR, Van Eyk JE. Proteomic alterations in heat shock protein 27 and identification of phosphoproteins in ascending aortic aneurysm associated with bicuspid and tricuspid aortic valve. Journal of Molecular and Cellular Cardiology. 43: 792-801. PMID 17949744 DOI: 10.1016/j.yjmcc.2007.08.011  0.16
2014 Carr SA, Abbatiello SE, Ackermann BL, Borchers C, Domon B, Deutsch EW, Grant RP, Hoofnagle AN, Hüttenhain R, Koomen JM, Liebler DC, Liu T, MacLean B, Mani DR, Mansfield E, ... ... Van Eyk J, et al. Targeted peptide measurements in biology and medicine: best practices for mass spectrometry-based assay development using a fit-for-purpose approach. Molecular & Cellular Proteomics : McP. 13: 907-17. PMID 24443746 DOI: 10.1074/Mcp.M113.036095  0.16
2022 Mastali M, Asif A, Fu Q, Wei J, Korley FK, Peacock WF, Sobhani K, Cook-Wiens G, Diniz MA, Merz CNB, Van Eyk JE. Ultra-highly sensitive cardiac troponin I: Age and sex differences in healthy individuals. American Heart Journal Plus : Cardiology Research and Practice. 13: 100110. PMID 38560066 DOI: 10.1016/j.ahjo.2022.100110  0.16
2015 Jaishy B, Zhang Q, Chung HS, Riehle C, Soto J, Jenkins S, Abel P, Cowart LA, Van Eyk JE, Abel ED. Lipid-induced NOX2 activation inhibits autophagic flux by impairing lysosomal enzyme activity. Journal of Lipid Research. 56: 546-61. PMID 25529920 DOI: 10.1194/jlr.M055152  0.16
2022 Barsky L, Speier W, Fuller G, Cheng S, Kim A, Joung S, Arnold C, Dhawan S, Lopez M, Mastali M, van den Broek I, Wei J, Spiegel B, Van Eyk JE, Bairey Merz CN, et al. Sex-based differences in remote monitoring of biometric, psychometric and biomarker indices in stable ischemic heart disease. Biology of Sex Differences. 13: 15. PMID 35410392 DOI: 10.1186/s13293-022-00423-5  0.159
2021 Marek-Iannucci S, Ozdemir AB, Moreira D, Gomez AC, Lane M, Porritt RA, Lee Y, Shimada K, Abe M, Stotland A, Zemmour D, Parker S, Sanchez-Lopez E, Van Eyk J, Gottlieb RA, et al. Autophagy-mitophagy induction attenuates cardiovascular inflammation in a murine model of Kawasaki disease vasculitis. Jci Insight. PMID 34403365 DOI: 10.1172/jci.insight.151981  0.159
2010 Williams LM, Fu Z, Dulloor P, Yan K, Strouse JJ, Savage W, Barron-Casella E, DeBaun MR, Van Eyk JE, Everett A, Casella JF. Identification of Thrombospondin-1 and L-Selectin as Potential Plasma Biomarkers of Silent Cerebral Infarct In Children with Sickle Cell Disease Using a Proteomic-Based Approach Blood. 116: 259-259. DOI: 10.1182/Blood.V116.21.259.259  0.159
2019 Shufelt C, Cheng S, Fuller G, Joung S, Mastali M, Mouapi K, Fu Q, Lopez M, Spiegel B, Van Eyk J, Merz CNB. RELATIONSHIP BETWEEN PATIENT-REPORTED OUTCOMES AND CARDIAC BIOMARKERS: THE PREDICTION, RISK, AND EVALUATION OF MAJOR ADVERSE CARDIAC EVENTS (PRE-MACE) STUDY BASELINE RESULTS Journal of the American College of Cardiology. 73: 1831. DOI: 10.1016/S0735-1097(19)32437-4  0.158
2018 Fu Q, Kowalski MP, Mastali M, Parker SJ, Sobhani K, van den Broek I, Hunter CL, Van Eyk JE. Highly Reproducible Automated Proteomics Sample Preparation Workflow for Quantitative Mass Spectrometry. Journal of Proteome Research. 17: 420-428. PMID 29083196 DOI: 10.1021/Acs.Jproteome.7B00623  0.156
2005 Graham DR, Garnham CP, Fu Q, Robbins J, Van Eyk JE. Improvements in two-dimensional gel electrophoresis by utilizing a low cost "in-house" neutral pH sodium dodecyl sulfate-polyacrylamide gel electrophoresis system. Proteomics. 5: 2309-14. PMID 15887185 DOI: 10.1002/pmic.200401249  0.155
2024 Marano P, Mouapi K, Kim A, Mastali M, van den Broek I, Manalo D, Fu Q, Cheng S, Shufelt C, Spiegel B, Bairey Merz CN, Van Eyk JE. Apolipoproteins Quantified Using Blood Volumetric Absorptive Microsampling and High-Throughput Mass Spectrometry for Risk Assessment in Ischemic Heart Disease. Circulation. 149: 970-972. PMID 38498608 DOI: 10.1161/CIRCULATIONAHA.123.066034  0.155
2018 Middleton RC, Rogers RG, De Couto G, Tseliou E, Luther K, Holewinski R, Soetkamp D, Van Eyk JE, Antes TJ, Marbán E. Newt cells secrete extracellular vesicles with therapeutic bioactivity in mammalian cardiomyocytes. Journal of Extracellular Vesicles. 7: 1456888. PMID 29696078 DOI: 10.1080/20013078.2018.1456888  0.153
2015 Parker SJ, Rost H, Rosenberger G, Collins BC, Malmström L, Amodei D, Venkatraman V, Raedschelders K, Van Eyk JE, Aebersold R. Identification of a Set of Conserved Eukaryotic Internal Retention Time Standards for Data-independent Acquisition Mass Spectrometry. Molecular & Cellular Proteomics : McP. 14: 2800-13. PMID 26199342 DOI: 10.1074/Mcp.O114.042267  0.153
2022 Nies MK, Yang J, Griffiths M, Damico R, Zhu J, Vaydia D, Fu Z, Brandal S, Austin ED, Ivy DD, Hassoun PM, Van Eyk JE, Everett AD. Proteomics discovery of pulmonary hypertension biomarkers: Insulin-like growth factor binding proteins are associated with disease severity. Pulmonary Circulation. 12: e12039. PMID 35514776 DOI: 10.1002/pul2.12039  0.153
2021 Fu Q, Murray CI, Karpov OA, Van Eyk JE. Automated proteomic sample preparation: The key component for high throughput and quantitative mass spectrometry analysis. Mass Spectrometry Reviews. e21750. PMID 34786750 DOI: 10.1002/mas.21750  0.153
2015 Subramanian K, Gianni D, Balla C, Assenza GE, Joshi M, Semigran MJ, Macgillivray TE, Van Eyk JE, Agnetti G, Paolocci N, Bamburg JR, Agrawal PB, Del Monte F. Cofilin-2 phosphorylation and sequestration in myocardial aggregates: novel pathogenetic mechanisms for idiopathic dilated cardiomyopathy. Journal of the American College of Cardiology. 65: 1199-1214. PMID 25814227 DOI: 10.1016/J.Jacc.2015.01.031  0.152
2021 McArdle A, Washington KE, Chazarin Orgel B, Binek A, Manalo DM, Rivas A, Ayres M, Pandey R, Phebus C, Raedschelders K, Fert-Bober J, Van Eyk JE. Discovery Proteomics for COVID-19: Where We Are Now. Journal of Proteome Research. 20: 4627-4639. PMID 34550702 DOI: 10.1021/acs.jproteome.1c00475  0.152
2023 Verma N, Khare D, Poe AJ, Amador C, Ghiam S, Fealy A, Ebrahimi S, Shadrokh O, Song XY, Santiskulvong C, Mastali M, Parker S, Stotland A, Van Eyk JE, Ljubimov AV, et al. MicroRNA and Protein Cargos of Human Limbal Epithelial Cell-Derived Exosomes and Their Regulatory Roles in Limbal Stromal Cells of Diabetic and Non-Diabetic Corneas. Cells. 12. PMID 37947602 DOI: 10.3390/cells12212524  0.152
2018 Lindsey ML, Bolli R, Canty JM, Du XJ, Frangogiannis NG, Frantz S, Gourdie RG, Holmes JW, Jones SP, Kloner RA, Lefer DJ, Liao R, Murphy E, Ping P, Przyklenk K, ... Van Eyk JE, et al. Guidelines for experimental models of myocardial ischemia and infarction. American Journal of Physiology. Heart and Circulatory Physiology. 314: H812-H838. PMID 29351451 DOI: 10.1152/Ajpheart.00335.2017  0.151
1995 Barth Z, Strauss JD, Heyder S, Van Eyk J, Wiesner RJ, Rüegg JC. Ca2+ sensitizing effects of EMD 53998 after troponin replacement in skinned fibres from porcine atria and ventricles. PflüGers Archiv : European Journal of Physiology. 430: 220-9. PMID 7675632 DOI: 10.1007/BF00374653  0.151
2008 Yamanaka S, Li J, Kania G, Elliott S, Wersto RP, Van Eyk J, Wobus AM, Boheler KR. Pluripotency of embryonic stem cells. Cell and Tissue Research. 331: 5-22. PMID 18026755 DOI: 10.1007/s00441-007-0520-5  0.15
2023 Momenzadeh A, Jiang Y, Kreimer S, Teigen LE, Zepeda CS, Haghani A, Mastali M, Song Y, Hutton A, Parker SJ, Van Eyk JE, Sundberg CW, Meyer JG. A Complete Workflow for High Throughput Human Single Skeletal Muscle Fiber Proteomics. Journal of the American Society For Mass Spectrometry. PMID 37463334 DOI: 10.1021/jasms.3c00072  0.15
2021 Lance EI, Faulcon LM, Fu Z, Yang J, Whyte-Stewart D, Strouse JJ, Barron-Casella E, Jones K, Van Eyk JE, Casella JF, Everett AD. Proteomic discovery in sickle cell disease: Elevated neurogranin levels in children with sickle cell disease. Proteomics. Clinical Applications. e2100003. PMID 33915030 DOI: 10.1002/prca.202100003  0.149
2019 Shufelt C, Dzubur E, Joung S, Fuller G, Mouapi KN, Van Den Broek I, Lopez M, Dhawan S, Arnold CW, Speier W, Mastali M, Fu Q, Van Eyk JE, Spiegel B, Merz CNB. A protocol integrating remote patient monitoring patient reported outcomes and cardiovascular biomarkers. Npj Digital Medicine. 2: 84. PMID 31508495 DOI: 10.1038/s41746-019-0145-6  0.148
2006 Kane LA, Yung CK, Agnetti G, Neverova I, Van Eyk JE. Optimization of paper bridge loading for 2-DE analysis in the basic pH region: application to the mitochondrial subproteome. Proteomics. 6: 5683-7. PMID 17022103 DOI: 10.1002/Pmic.200600267  0.147
2016 Andres AM, Kooren JA, Parker SJ, Tucker KC, Ravindran N, Ito BR, Huang C, Venkatraman V, Van Eyk JE, Gottlieb RA, Mentzer RM. Discordant signaling and autophagy response to fasting in hearts of obese mice: Implications for ischemia tolerance. American Journal of Physiology. Heart and Circulatory Physiology. 311: H219-28. PMID 27199111 DOI: 10.1152/Ajpheart.00041.2016  0.147
2023 Momenzadeh A, Jiang Y, Kreimer S, Teigen LE, Zepeda CS, Haghani A, Mastali M, Song Y, Hutton A, Parker SJ, Van Eyk JE, Sundberg CW, Meyer JG. Complete Workflow for High Throughput Human Single Skeletal Muscle Fiber Proteomics. Biorxiv : the Preprint Server For Biology. PMID 36865126 DOI: 10.1101/2023.02.23.529600  0.146
2011 Pan X, Kane LA, Van Eyk JE, Coulombe PA. Type I keratin 17 protein is phosphorylated on serine 44 by p90 ribosomal protein S6 kinase 1 (RSK1) in a growth- and stress-dependent fashion. The Journal of Biological Chemistry. 286: 42403-13. PMID 22006917 DOI: 10.1074/Jbc.M111.302042  0.146
2008 Mayr M, Van Eyk JE. Cardiovascular proteomics. Proteomics. Clinical Applications. 2: 785-6. PMID 21136878 DOI: 10.1002/prca.200890020  0.145
2010 Ellenbogen KA, Gold MR, Meyer TE, Fernndez Lozano I, Mittal S, Waggoner AD, Lemke B, Singh JP, Spinale FG, Van Eyk JE, Whitehill J, Weiner S, Bedi M, Rapkin J, Stein KM. Primary results from the SmartDelay determined AV optimization: a comparison to other AV delay methods used in cardiac resynchronization therapy (SMART-AV) trial: a randomized trial comparing empirical, echocardiography-guided, and algorithmic atrioventricular delay programming in cardiac resynchronization therapy. Circulation. 122: 2660-8. PMID 21098426 DOI: 10.1161/Circulationaha.110.992552  0.144
2012 Lam MP, Vivanco F, Scholten A, Hermjakob H, Van Eyk J, Ping P. HUPO 2011: The new Cardiovascular Initiative - integrating proteomics and cardiovascular biology in health and disease. Proteomics. 12: 749-51. PMID 22539426 DOI: 10.1002/Pmic.201270015  0.144
2019 Cao DY, Spivia WR, Veiras LC, Khan Z, Peng Z, Jones AE, Bernstein EA, Saito S, Okwan-Duodu D, Parker SJ, Giani JF, Divakaruni AS, Van Eyk JE, Bernstein KE. ACE over expression in myeloid cells increases oxidative metabolism and cellular ATP. The Journal of Biological Chemistry. PMID 31871049 DOI: 10.1074/Jbc.Ra119.011244  0.144
2017 Zhang S, Raedschelders K, Santos M, Van Eyk JE. Profiling B-Type Natriuretic Peptide Cleavage Peptidoforms in Human Plasma by Capillary Electrophoresis with Electrospray Ionization Mass Spectrometry. Journal of Proteome Research. 16: 4515-4522. PMID 28861997 DOI: 10.1021/acs.jproteome.7b00482  0.143
2012 Ashley EA, Hershberger RE, Caleshu C, Ellinor PT, Garcia JG, Herrington DM, Ho CY, Johnson JA, Kittner SJ, Macrae CA, Mudd-Martin G, Rader DJ, Roden DM, Scholes D, Sellke FW, ... ... Van Eyk J, et al. Genetics and cardiovascular disease: a policy statement from the American Heart Association. Circulation. 126: 142-57. PMID 22645291 DOI: 10.1161/Cir.0B013E31825B07F8  0.142
2015 Semba RD, Lam M, Sun K, Zhang P, Schaumberg DA, Ferrucci L, Ping P, Van Eyk JE. Priorities and trends in the study of proteins in eye research, 1924-2014. Proteomics. Clinical Applications. 9: 1105-22. PMID 26123431 DOI: 10.1002/Prca.201500006  0.142
2018 Sobhani K, Nieves Castro DK, Fu Q, Gottlieb RA, Van Eyk JE, Noel Bairey Merz C. Sex differences in ischemic heart disease and heart failure biomarkers. Biology of Sex Differences. 9: 43. PMID 30223899 DOI: 10.1186/s13293-018-0201-y  0.142
2010 Fu Q, Zhu J, Van Eyk JE. Comparison of multiplex immunoassay platforms. Clinical Chemistry. 56: 314-8. PMID 20022982 DOI: 10.1373/clinchem.2009.135087  0.142
2011 Agnetti G, Husberg C, Van Eyk JE. Divide and conquer: the application of organelle proteomics to heart failure. Circulation Research. 108: 512-26. PMID 21335433 DOI: 10.1161/CIRCRESAHA.110.226910  0.14
2006 Neverova I, Wyss B, Brown H, Creasy J, Ropchan G, Van Eyk J. A68. Myocardial roteome profiling in a swine ischemic-induced heart failure model Journal of Molecular and Cellular Cardiology. 40: 889-890. DOI: 10.1016/j.yjmcc.2006.03.357  0.139
2023 Robinson AE, Binek A, Ramani K, Sundararaman N, Barbier-Torres L, Murray B, Venkatraman V, Kreimer S, Ardle AM, Noureddin M, Fernández-Ramos D, Lopitz-Otsoa F, Gutiérrez de Juan V, Millet O, Mato JM, ... ... Van Eyk JE, et al. Hyperphosphorylation of hepatic proteome characterizes nonalcoholic fatty liver disease in S-adenosylmethionine deficiency. Iscience. 26: 105987. PMID 36756374 DOI: 10.1016/j.isci.2023.105987  0.138
2008 Graham DR, Mitsak MJ, Elliott ST, Chen D, Whelan SA, Hart GW, Van Eyk JE. Two-dimensional gel-based approaches for the assessment of N-Linked and O-GlcNAc glycosylation in human and simian immunodeficiency viruses. Proteomics. 8: 4919-30. PMID 19072736 DOI: 10.1002/Pmic.200800608  0.137
2021 Mc Ardle A, Binek A, Moradian A, Chazarin Orgel B, Rivas A, Washington KE, Phebus C, Manalo DM, Go J, Venkatraman V, Coutelin Johnson CW, Fu Q, Cheng S, Raedschelders K, Fert-Bober J, ... ... Van Eyk JE, et al. Standardized Workflow for Precise Mid- and High-Throughput Proteomics of Blood Biofluids. Clinical Chemistry. PMID 34687543 DOI: 10.1093/clinchem/hvab202  0.137
2018 Spinale FG, Meyer TE, Stolen CM, Van Eyk JE, Gold MR, Mittal S, DeSantis S, Wold N, Beshai JF, Stein KM, Ellenbogen KA. Development of a Biomarker Panel to Predict Cardiac Resynchronization Therapy Response: Results from the SMART-AV Trial. Heart Rhythm. PMID 30476543 DOI: 10.1016/J.Hrthm.2018.11.026  0.136
2022 Lau ES, Binek A, Parker SJ, Shah SH, Zanni MV, Van Eyk JE, Ho JE. Sexual Dimorphism in Cardiovascular Biomarkers: Clinical and Research Implications. Circulation Research. 130: 578-592. PMID 35175850 DOI: 10.1161/CIRCRESAHA.121.319916  0.136
2020 Rosa-Fernandes L, Barbosa RH, Dos Santos MLB, Angeli CB, Silva TP, Melo RCN, de Oliveira GS, Lemos B, Van Eyk JE, Larsen MR, Cardoso CA, Palmisano G. Cellular Imprinting Proteomics Assay: A novel method for detection of neural and ocular disorders applied to Congenital Zika virus Syndrome. Journal of Proteome Research. PMID 32686424 DOI: 10.1021/acs.jproteome.0c00320  0.135
2008 Fu Q, Sheng S, Van Eyk JE. Development of Biomarker Development Pipeline: Search for Myocardial Ischemia Biomarkers Clinical Proteomics: From Diagnosis to Therapy. 241-261. DOI: 10.1002/9783527622153.ch17  0.134
2010 Patterson SD, Van Eyk JE, Banks RE. Report from the Wellcome Trust/EBA “Perspectives in Clinical Proteomics” retreat--a strategy to implement next-generation proteomic analyses to the clinic for patient benefit: pathway to translation. Proteomics. Clinical Applications. 4: 883-7. PMID 21179889 DOI: 10.1002/prca.201000113  0.133
2021 Porritt RA, Binek A, Paschold L, Noval Rivas M, Mc Ardle A, Yonker LM, Alter G, Chandnani HK, Lopez M, Fasano A, Van Eyk JE, Binder M, Arditi M. The autoimmune signature of hyperinflammatory multisystem inflammatory syndrome in children. The Journal of Clinical Investigation. PMID 34437303 DOI: 10.1172/JCI151520  0.133
2012 Chung BM, Murray CI, Van Eyk JE, Coulombe PA. Identification of novel interaction between annexin A2 and keratin 17: evidence for reciprocal regulation. The Journal of Biological Chemistry. 287: 7573-81. PMID 22235123 DOI: 10.1074/Jbc.M111.301549  0.133
2008 Feltes CM, Van Eyk J, Rabb H. Distant-organ changes after acute kidney injury. Nephron. Physiology. 109: p80-4. PMID 18802379 DOI: 10.1159/000142940  0.131
2007 Mischak H, Apweiler R, Banks RE, Conaway M, Coon J, Dominiczak A, Ehrich JH, Fliser D, Girolami M, Hermjakob H, Hochstrasser D, Jankowski J, Julian BA, Kolch W, Massy ZA, ... ... Van Eyk JE, et al. Clinical proteomics: A need to define the field and to begin to set adequate standards. Proteomics. Clinical Applications. 1: 148-56. PMID 21136664 DOI: 10.1002/Prca.200600771  0.13
2022 Stachowicz A, Pandey R, Sundararaman N, Venkatraman V, Van Eyk JE, Fert-Bober J. Protein arginine deiminase 2 (PAD2) modulates the polarization of THP-1 macrophages to the anti-inflammatory M2 phenotype. Journal of Inflammation (London, England). 19: 20. PMID 36401289 DOI: 10.1186/s12950-022-00317-8  0.129
2022 Shen M, Chang YT, Wu CT, Parker SJ, Saylor G, Wang Y, Yu G, Van Eyk JE, Clarke R, Herrington DM, Wang Y. Comparative assessment and novel strategy on methods for imputing proteomics data. Scientific Reports. 12: 1067. PMID 35058491 DOI: 10.1038/s41598-022-04938-0  0.128
2013 Kirk JA, Zhang P, Murphy AM, Van Eyk JE. Troponin I alterations detected by multiple-reaction monitoring: how might this impact the study of heart failure? Expert Review of Proteomics. 10: 5-8. PMID 23414352 DOI: 10.1586/Epr.12.77  0.128
2010 Eagle KA, Ginsburg GS, Musunuru K, Aird WC, Balaban RS, Bennett SK, Blumenthal RS, Coughlin SR, Davidson KW, Frohlich ED, Greenland P, Jarvik GP, Libby P, Pepine CJ, Ruskin JN, ... ... Van Eyk JE, et al. Identifying patients at high risk of a cardiovascular event in the near future: current status and future directions: report of a national heart, lung, and blood institute working group. Circulation. 121: 1447-54. PMID 20351302 DOI: 10.1161/Circulationaha.109.904029  0.128
2018 Wang SB, Venkatraman V, Crowgey EL, Liu T, Fu Z, Holewinski R, Ranek M, Kass DA, O'Rourke B, Van Eyk JE. Protein -Nitrosylation Controls Glycogen Synthase Kinase 3β Function Independent of Its Phosphorylation State. Circulation Research. 122: 1517-1531. PMID 29563102 DOI: 10.1161/CIRCRESAHA.118.312789  0.128
2018 Speier W, Dzubur E, Zide M, Shufelt C, Joung S, Van Eyk JE, Bairey Merz CN, Lopez M, Spiegel B, Arnold C. Evaluating utility and compliance in a patient-based eHealth study using continuous-time heart rate and activity trackers. Journal of the American Medical Informatics Association : Jamia. 25: 1386-1391. PMID 29850807 DOI: 10.1093/Jamia/Ocy067  0.127
2015 Van Eyk JE. Universal therapeutic targeting of age-related protein quality control system dysfunction in chronic diseases? Trends in Cardiovascular Medicine. 25: 248-9. PMID 25802225 DOI: 10.1016/j.tcm.2015.01.012  0.127
2013 Chung HS, Wang SB, Venkatraman V, Murray CI, Van Eyk JE. Cysteine oxidative posttranslational modifications: emerging regulation in the cardiovascular system. Circulation Research. 112: 382-92. PMID 23329793 DOI: 10.1161/CIRCRESAHA.112.268680  0.126
2018 Parker SJ, Stotland A, MacFarlane E, Wilson N, Orosco A, Venkatraman V, Madrid K, Gottlieb R, Dietz HC, Van Eyk JE. Proteomics reveals Rictor as a noncanonical TGF-β signaling target during aneurysm progression in Marfan mice. American Journal of Physiology. Heart and Circulatory Physiology. 315: H1112-H1126. PMID 30004239 DOI: 10.1152/Ajpheart.00089.2018  0.126
2004 Simpson JA, Van Eyk J, Iscoe S. Respiratory muscle injury, fatigue and serum skeletal troponin I in rat. The Journal of Physiology. 554: 891-903. PMID 14673191 DOI: 10.1113/jphysiol.2003.051318  0.126
2014 Ge Y, Van Eyk J. Cardiovascular disease: the leap towards translational and clinical proteomics. Proteomics. Clinical Applications. 8: 473-5. PMID 25123748 DOI: 10.1002/Prca.201470044  0.126
2011 Ellenbogen KA, Gold MR, Meyer TE, Lozano IF, Mittal S, Waggoner AD, Lemke B, Singh JP, Spinale FG, Van Eyk JE, Whitehill J, Weiner S, Bedi M, Rapkin J, Stein KM. Response to Letter Regarding Article, “Primary Results From the SmartDelay Determined AV Optimization: A Comparison to Other AV Delay Methods Used in Cardiac Resynchronization Therapy (SMART-AV) Trial: A Randomized Trial Comparing Empirical, Echocardiography-Guided and Algorithmic Atrioventricular Delay Programming in Cardiac Resynchronization Therapy” Circulation. 124. DOI: 10.1161/Circulationaha.111.027284  0.125
2013 Faulcon LM, Fu Z, Dulloor P, Barron-Casella E, Savage W, Jennings JM, Van Eyk JE, Debaun M, Casella JF, Everett A. Thrombospondin-1 and L-selectin are associated with silent cerebral infarct in children with sickle cell anaemia. British Journal of Haematology. 162: 421-4. PMID 23672305 DOI: 10.1111/Bjh.12374  0.125
2002 McDonald T, Neverova I, Ko Y, Pedersen PL, Van Eyk JE. 01 A proteomic database of rat liver inner mitochondrial membrane proteins Journal of Molecular and Cellular Cardiology. 34: A29. DOI: 10.1016/S0022-2828(02)90172-0  0.124
2010 Balabaskaran Nina P, Dudkina NV, Kane LA, van Eyk JE, Boekema EJ, Mather MW, Vaidya AB. Highly divergent mitochondrial ATP synthase complexes in Tetrahymena thermophila. Plos Biology. 8: e1000418. PMID 20644710 DOI: 10.1371/Journal.Pbio.1000418  0.124
2015 Rainer P, Lee D, Sorge M, Baracca A, Solaini G, Guarnieri C, Glabe C, Paolocci N, O'Rourke B, Tomaselli G, Kass D, Van Eyk J, Agnetti G. Modified desmin pre-amyloid oligomers are increased in experimental heart failure Vascular Pharmacology. 75: 40. DOI: 10.1016/j.vph.2015.11.003  0.124
2008 Tarasov KV, Tarasova YS, Tam WL, Riordon DR, Elliott ST, Kania G, Li J, Yamanaka S, Crider DG, Testa G, Li RA, Lim B, Stewart CL, Liu Y, Van Eyk JE, et al. B-MYB is essential for normal cell cycle progression and chromosomal stability of embryonic stem cells. Plos One. 3: e2478. PMID 18575582 DOI: 10.1371/Journal.Pone.0002478  0.124
2015 Hsu CY, Ballard S, Batlle D, Bonventre JV, Böttinger EP, Feldman HI, Klein JB, Coresh J, Eckfeldt JH, Inker LA, Kimmel PL, Kusek JW, Liu KD, Mauer M, Mifflin TE, ... Van Eyk JE, et al. Cross-Disciplinary Biomarkers Research: Lessons Learned by the CKD Biomarkers Consortium. Clinical Journal of the American Society of Nephrology : Cjasn. 10: 894-902. PMID 25739849 DOI: 10.2215/Cjn.11541114  0.123
2022 Plummer JT, Contreras D, Zhang W, Binek A, Zhang R, Dezem F, Chen SS, Davis BD, Sincuir Martinez J, Stotland A, Kreimer S, Makhoul E, Heneidi S, Eno C, Shin B, ... ... Van Eyk JE, et al. USA SARS-CoV-2 Epsilon Variant: Though Highly Transmissible has an Adjusted Muted Host T-Cell Response. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 35438777 DOI: 10.1093/cid/ciac295  0.122
2002 Colantonio DA, Pickett W, Brison RJ, Collier CE, Van Eyk JE. Detection of cardiac troponin I early after onset of chest pain in six patients. Clinical Chemistry. 48: 668-71. PMID 11901073  0.121
2024 Hendricks NG, Bhosale SD, Keoseyan AJ, Ortiz J, Stotland A, Seyedmohammad S, Nguyen CDL, Bui J, Moradian A, Mockus SM, Van Eyk JE. An inflection point in high-throughput proteomics with Orbitrap Astral: analysis of biofluids, cells, and tissues. Biorxiv : the Preprint Server For Biology. PMID 38712179 DOI: 10.1101/2024.04.26.591396  0.12
2024 Alfahel L, Gschwendtberger T, Kozareva V, Dumas L, Gibbs R, Kertser A, Baruch K, Zaccai S, Kahn J, Thau-Habermann N, Eggenschwiler R, Sterneckert J, Hermann A, Sundararaman N, Vaibhav V, ... Van Eyk JE, et al. Targeting low levels of MIF expression as a potential therapeutic strategy for ALS. Cell Reports. Medicine. 101546. PMID 38703766 DOI: 10.1016/j.xcrm.2024.101546  0.12
2012 Wang M, Fu Z, Wu J, Zhang J, Jiang L, Khazan B, Telljohann R, Zhao M, Krug AW, Pikilidou M, Monticone RE, Wersto R, Van Eyk J, Lakatta EG. MFG-E8 activates proliferation of vascular smooth muscle cells via integrin signaling. Aging Cell. 11: 500-8. PMID 22385834 DOI: 10.1111/j.1474-9726.2012.00813.x  0.119
2016 Holewinski RJ, Parker SJ, Matlock AD, Venkatraman V, Van Eyk JE. Methods for SWATH™: Data Independent Acquisition on TripleTOF Mass Spectrometers. Methods in Molecular Biology (Clifton, N.J.). 1410: 265-79. PMID 26867750 DOI: 10.1007/978-1-4939-3524-6_16  0.119
2020 Porritt RA, Paschold L, Rivas MN, Cheng MH, Yonker LM, Chandnani H, Lopez M, Simnica D, Schultheiß C, Santiskulvong C, Van Eyk J, Fasano A, Bahar I, Binder M, Arditi M. Identification of a unique TCR repertoire, consistent with a superantigen selection process in Children with Multi-system Inflammatory Syndrome. Biorxiv : the Preprint Server For Biology. PMID 33200133 DOI: 10.1101/2020.11.09.372169  0.118
2017 Zhang P, Zhu M, Geng-Spyropoulos M, Shardell M, Gonzalez-Freire M, Gudnason V, Eiriksdottir G, Schaumberg D, Van Eyk JE, Ferrucci L, Semba RD. A novel, multiplexed targeted mass spectrometry assay for quantification of complement factor H (CFH) variants and CFH-related proteins 1-5 in human plasma. Proteomics. 17. PMID 27647805 DOI: 10.1002/Pmic.201600237  0.118
2021 Porritt RA, Paschold L, Noval Rivas M, Cheng MH, Yonker LM, Chandnani H, Lopez M, Simnica D, Schultheiß C, Santiskulvong C, van Eyk J, McCormick JK, Fasano A, Bahar I, Binder M, et al. HLA class I-associated expansion of TRBV11-2 T cells in Multisystem Inflammatory Syndrome in Children. The Journal of Clinical Investigation. PMID 33705359 DOI: 10.1172/JCI146614  0.117
2022 Barbier-Torres L, Murray B, Yang JW, Wang J, Matsuda M, Robinson A, Binek A, Fan W, Fernández-Ramos D, Lopitz-Otsoa F, Luque-Urbano M, Millet O, Mavila N, Peng H, Ramani K, ... ... Van Eyk JE, et al. Depletion of mitochondrial methionine adenosyltransferase α1 triggers mitochondrial dysfunction in alcohol-associated liver disease. Nature Communications. 13: 557. PMID 35091576 DOI: 10.1038/s41467-022-28201-2  0.116
2022 Syed F, Singhal D, Raedschelders K, Krishnan P, Bone RN, McLaughlin MR, Van Eyk JE, Mirmira RG, Yang ML, Mamula MJ, Wu H, Liu X, Evans-Molina C. A discovery-based proteomics approach identifies protein disulphide isomerase (PDIA1) as a biomarker of β cell stress in type 1 diabetes. Ebiomedicine. 87: 104379. PMID 36463755 DOI: 10.1016/j.ebiom.2022.104379  0.116
2014 Aebersold R, Bader GD, Edwards AM, van Eyk J, Kussman M, Qin J, Omenn GS. Highlights of B/D-HPP and HPP Resource Pillar Workshops at 12th Annual HUPO World Congress of Proteomics: September 14-18, 2013, Yokohama, Japan. Proteomics. 14: 975-88. PMID 24596128 DOI: 10.1002/Pmic.201400041  0.116
2012 Stastna M, Van Eyk JE. Improved and emerging gel-free separation and detection methods for proteomics. Proteomics. 12: 2902-3. PMID 23081939 DOI: 10.1002/pmic.201270134  0.115
2002 Xu W, Liu Y, Wang S, McDonald T, Van Eyk JE, Sidor A, O'Rourke B. Cytoprotective role of Ca2+- activated K+ channels in the cardiac inner mitochondrial membrane. Science (New York, N.Y.). 298: 1029-33. PMID 12411707 DOI: 10.1126/science.1074360  0.114
2021 Chen L, Lu Y, Wu CT, Clarke R, Yu G, Van Eyk JE, Herrington DM, Wang Y. Data-driven detection of subtype-specific differentially expressed genes. Scientific Reports. 11: 332. PMID 33432005 DOI: 10.1038/s41598-020-79704-1  0.114
2011 Stastna M, Behrens A, McDonnell PJ, Van Eyk JE. Analysis of protein composition of rabbit aqueous humor following two different cataract surgery incision procedures using 2-DE and LC-MS/MS. Proteome Science. 9: 8. PMID 21306621 DOI: 10.1186/1477-5956-9-8  0.112
2017 Hixson JE, Jun G, Shimmin LC, Wang Y, Yu G, Mao C, Warren AS, Howard TD, Heide RSV, Van Eyk J, Wang Y, Herrington DM. Whole Exome Sequencing to Identify Genetic Variants Associated with Raised Atherosclerotic Lesions in Young Persons. Scientific Reports. 7: 4091. PMID 28642624 DOI: 10.1038/S41598-017-04433-X  0.111
2024 Moradian A, Goonatilleke E, Lin TT, Hatten-Beck M, Emrick M, Schepmoes AA, Fillmore TL, MacCoss MJ, Sechi S, Sobhani K, Little R, Kabytaev K, van Eyk JE, Qian WJ, Hoofnagle AN. Interlaboratory Comparison of Antibody-Free LC-MS/MS Measurements of C-peptide and Insulin. Clinical Chemistry. PMID 38549041 DOI: 10.1093/clinchem/hvae034  0.11
2014 Mathias RA, Huang L, Vergara CI, Gao L, Rafaels NM, Potee J, Campbell M, Masuko H, Fert-Bober J, Snider J, Taub M, Ruczinski I, Beaty TH, Van Eyk JE, Barnes KC. Sequencing Of The ST2 Gene and The Identification Of Genetic Determinants Of Serum Total ST2 Levels: Strong Evidence For Replication Across European and African American Populations Journal of Allergy and Clinical Immunology. 133: AB247. DOI: 10.1016/J.Jaci.2013.12.878  0.108
2013 Nirmalan N, Banks R, Van Eyk JE. Proteomic analysis of formalin fixed tissue. Proteomics. Clinical Applications. 7: 215-6. PMID 23585051 DOI: 10.1002/prca.201370024  0.107
2009 Gao P, Tchernyshyov I, Chang TC, Lee YS, Kita K, Ochi T, Zeller KI, De Marzo AM, Van Eyk JE, Mendell JT, Dang CV. C-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism Nature. 458: 762-765. PMID 19219026 DOI: 10.1038/Nature07823  0.106
2017 van den Broek I, Sobhani K, Van Eyk JE. Advances in quantifying apolipoproteins using LC-MS/MS technology: implications for the clinic. Expert Review of Proteomics. 14: 869-880. PMID 28870113 DOI: 10.1080/14789450.2017.1374859  0.104
2015 Doyle JJ, Doyle AJ, Wilson NK, Habashi JP, Bedja D, Whitworth RE, Lindsay ME, Schoenhoff F, Myers L, Huso N, Bachir S, Squires O, Rusholme B, Ehsan H, Huso D, ... Van Eyk JE, et al. A deleterious gene-by-environment interaction imposed by calcium channel blockers in Marfan syndrome. Elife. 4. PMID 26506064 DOI: 10.7554/Elife.08648  0.104
2011 Van Eyk JE. Overview: the maturing of proteomics in cardiovascular research. Circulation Research. 108: 490-8. PMID 21335431 DOI: 10.1161/CIRCRESAHA.110.226894  0.103
2014 Pandey D, Bhunia A, Oh YJ, Chang F, Bergman Y, Kim JH, Serbo J, Boronina TN, Cole RN, Van Eyk J, Remaley AT, Berkowitz DE, Romer LH. OxLDL triggers retrograde translocation of arginase2 in aortic endothelial cells via ROCK and mitochondrial processing peptidase. Circulation Research. 115: 450-9. PMID 24903103 DOI: 10.1161/CIRCRESAHA.115.304262  0.101
2006 Boyd JG, Jahed A, McDonald TG, Krol KM, Van Eyk JE, Doucette R, Kawaja MD. Proteomic evaluation reveals that olfactory ensheathing cells but not Schwann cells express calponin. Glia. 53: 434-40. PMID 16345031 DOI: 10.1002/glia.20299  0.101
2018 Van Eyk JE, Snyder MP. Precision Medicine: Role of Proteomics in Changing Clinical Management and Care. Journal of Proteome Research. PMID 30296097 DOI: 10.1021/acs.jproteome.8b00504  0.1
2009 Schoenhoff FS, Fu Q, Van Eyk JE. Cardiovascular proteomics: implications for clinical applications. Clinics in Laboratory Medicine. 29: 87-99. PMID 19389553 DOI: 10.1016/j.cll.2009.01.005  0.1
2019 Rajput PS, Lamb J, Kothari S, Pereira B, Soetkamp D, Wang Y, Tang J, Van Eyk JE, Mullins ES, Lyden PD. Neuron-generated thrombin induces a protective astrocyte response via protease activated receptors. Glia. PMID 31453648 DOI: 10.1002/Glia.23714  0.098
2020 AlBadri A, Wei J, Quesada O, Mehta PK, Xiao Y, Ko YA, Anderson RD, Petersen J, Azarbal B, Samuels B, Henry TD, Cook-Wiens G, Handberg EM, Van Eyk J, Pepine CJ, et al. Coronary Vascular Function and Cardiomyocyte Injury: A Report WISE-CVD. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120314260. PMID 33028098 DOI: 10.1161/ATVBAHA.120.314260  0.098
2016 Rucki AA, Foley K, Zhang P, Xiao Q, Kleponis J, Wu A, Sharma R, Mo G, Liu A, Van Eyk J, Jaffee EM, Zheng L. Heterogeneous stromal signaling within the tumor microenvironment controls the metastasis of pancreatic cancer. Cancer Research. PMID 27821486 DOI: 10.1158/0008-5472.Can-16-1383  0.096
2023 Du D, Bhardwaj S, Parker SJ, Cheng Z, Zhang Z, Lu Y, Van Eyk JE, Yu G, Clarke R, Herrington DM, Wang Y. ABDS: tool suite for analyzing biologically diverse samples. Biorxiv : the Preprint Server For Biology. PMID 37461566 DOI: 10.1101/2023.07.05.547797  0.095
2021 Chen L, Wu CT, Lin CH, Dai R, Liu C, Clarke R, Yu G, Van Eyk JE, Herrington DM, Wang Y. swCAM: estimation of subtype-specific expressions in individual samples with unsupervised sample-wise deconvolution. Bioinformatics (Oxford, England). PMID 34904628 DOI: 10.1093/bioinformatics/btab839  0.095
2013 Romero V, Fert-Bober J, Nigrovic PA, Darrah E, Haque UJ, Lee DM, van Eyk J, Rosen A, Andrade F. Immune-mediated pore-forming pathways induce cellular hypercitrullination and generate citrullinated autoantigens in rheumatoid arthritis. Science Translational Medicine. 5: 209ra150. PMID 24174326 DOI: 10.1126/Scitranslmed.3006869  0.095
2002 Arrell D, Elliott S, Neverova I, Marban E, Van Eyk JE. 01 Proteomic analysis of preconditioning reveals post-translational modification of the F1Fo ATPase β subunit Journal of Molecular and Cellular Cardiology. 34: A33. DOI: 10.1016/S0022-2828(02)90185-9  0.094
2011 Savage WJ, Barron-Casella E, Fu Z, Dulloor P, Williams L, Crain BJ, White DA, Jennings JM, Van Eyk JE, Debaun MR, Everett A, Casella JF. Plasma glial fibrillary acidic protein levels in children with sickle cell disease. American Journal of Hematology. 86: 427-9. PMID 21523806 DOI: 10.1002/Ajh.21995  0.093
2013 Myerburg RJ, Halperin H, Egan DA, Boineau R, Chugh SS, Gillis AM, Goldhaber JI, Lathrop DA, Liu P, Niemann JT, Ornato JP, Sopko G, Van Eyk JE, Walcott GP, Weisfeldt ML, et al. Pulseless electric activity: definition, causes, mechanisms, management, and research priorities for the next decade: report from a National Heart, Lung, and Blood Institute workshop. Circulation. 128: 2532-41. PMID 24297818 DOI: 10.1161/CIRCULATIONAHA.113.004490  0.092
2015 McMahan Z, Schoenhoff F, Van Eyk JE, Wigley FM, Hummers LK. Biomarkers of pulmonary hypertension in patients with scleroderma: a case-control study. Arthritis Research & Therapy. 17: 201. PMID 26245195 DOI: 10.1186/s13075-015-0712-4  0.09
2010 Kane LA, Youngman MJ, Jensen RE, Van Eyk JE. Phosphorylation of the F(1)F(o) ATP synthase beta subunit: functional and structural consequences assessed in a model system. Circulation Research. 106: 504-13. PMID 20035080 DOI: 10.1161/Circresaha.109.214155  0.09
2015 Agrawal S, Van Eyk J, Sobhani K, Wei J, Bairey Merz CN. Sex, Myocardial Infarction, and the Failure of Risk Scores in Women. Journal of Women's Health (2002). PMID 26288193 DOI: 10.1089/jwh.2015.5412  0.089
2024 Osipov A, Nikolic O, Gertych A, Parker S, Hendifar A, Singh P, Filippova D, Dagliyan G, Ferrone CR, Zheng L, Moore JH, Tourtellotte W, Van Eyk JE, Theodorescu D. The Molecular Twin artificial-intelligence platform integrates multi-omic data to predict outcomes for pancreatic adenocarcinoma patients. Nature Cancer. PMID 38253803 DOI: 10.1038/s43018-023-00697-7  0.089
2022 Lu Y, Wu CT, Parker SJ, Cheng Z, Saylor G, Van Eyk JE, Yu G, Clarke R, Herrington DM, Wang Y. COT: an efficient and accurate method for detecting marker genes among many subtypes. Bioinformatics Advances. 2: vbac037. PMID 35673616 DOI: 10.1093/bioadv/vbac037  0.088
2012 Murray CI, Van Eyk JE. Chasing cysteine oxidative modifications: proteomic tools for characterizing cysteine redox status. Circulation. Cardiovascular Genetics. 5: 591. PMID 23074338 DOI: 10.1161/CIRCGENETICS.111.961425  0.088
2010 Köttgen A, Hwang SJ, Larson MG, Van Eyk JE, Fu Q, Benjamin EJ, Dehghan A, Glazer NL, Kao WH, Harris TB, Gudnason V, Shlipak MG, Yang Q, Coresh J, Levy D, et al. Uromodulin levels associate with a common UMOD variant and risk for incident CKD. Journal of the American Society of Nephrology : Jasn. 21: 337-44. PMID 19959715 DOI: 10.1681/Asn.2009070725  0.087
2004 Van Eyk JE. Lessons from old and new kinases. Circulation Research. 94: 135-7. PMID 14764647 DOI: 10.1161/01.RES.0000117526.17737.40  0.087
2023 Muranaka H, Hendifar A, Osipov A, Moshayedi N, Placencio-Hickok V, Tatonetti N, Stotland A, Parker S, Van Eyk J, Pandol SJ, Bhowmick NA, Gong J. Plasma Metabolomics Predicts Chemotherapy Response in Advanced Pancreatic Cancer. Cancers. 15. PMID 37296982 DOI: 10.3390/cancers15113020  0.086
2023 Koronyo Y, Rentsendorj A, Mirzaei N, Regis GC, Sheyn J, Shi H, Barron E, Cook-Wiens G, Rodriguez AR, Medeiros R, Paulo JA, Gupta VB, Kramerov AA, Ljubimov AV, Van Eyk JE, et al. Retinal pathological features and proteome signatures of Alzheimer's disease. Acta Neuropathologica. PMID 36773106 DOI: 10.1007/s00401-023-02548-2  0.086
2022 Dupont V, Berg AH, Yamashita M, Huang C, Covarrubias AE, Ali S, Stotland A, Van Eyk JE, Jim B, Thadhani R, Karumanchi SA. Impaired renal reserve contributes to preeclampsia via the kynurenine and soluble fms-like tyrosine kinase 1 pathway. The Journal of Clinical Investigation. PMID 35943814 DOI: 10.1172/JCI158346  0.086
2017 Wright I, Van Eyk JE. A Roadmap to Successful Clinical Proteomics. Clinical Chemistry. 63: 245-247. PMID 27864386 DOI: 10.1373/clinchem.2016.254664  0.085
2023 Lewis MI, Shapiro S, Oudiz RJ, Nakamura M, Geft D, Matusov Y, Hage A, Tapson VF, Henry TD, Azizad P, Saggar R, Mirocha J, Karpov OA, Van Eyk JE, Marbán E. The ALPHA phase 1 study: pulmonary ArteriaL hypertension treated with CardiosPHere-Derived allogeneic stem cells. Ebiomedicine. 104900. PMID 38092579 DOI: 10.1016/j.ebiom.2023.104900  0.084
2012 Giles JT, Fert-Bober J, Park JK, Bingham CO, Andrade F, Fox-Talbot K, Pappas D, Rosen A, van Eyk J, Bathon JM, Halushka MK. Myocardial citrullination in rheumatoid arthritis: a correlative histopathologic study. Arthritis Research & Therapy. 14: R39. PMID 22364592 DOI: 10.1186/Ar3752  0.083
2008 Pearson GD, Devereux R, Loeys B, Maslen C, Milewicz D, Pyeritz R, Ramirez F, Rifkin D, Sakai L, Svensson L, Wessels A, Van Eyk J, Dietz HC. Report of the National Heart, Lung, and Blood Institute and National Marfan Foundation Working Group on research in Marfan syndrome and related disorders. Circulation. 118: 785-91. PMID 18695204 DOI: 10.1161/Circulationaha.108.783753  0.083
2021 Liu Y, Ebinger JE, Mostafa R, Budde P, Gajewski J, Walker B, Joung S, Wu M, Bräutigam M, Hesping F, Rupieper E, Schubert AS, Zucht HD, Braun J, Melmed GY, ... ... Van Eyk JE, et al. Paradoxical sex-specific patterns of autoantibody response to SARS-CoV-2 infection. Journal of Translational Medicine. 19: 524. PMID 34965855 DOI: 10.1186/s12967-021-03184-8  0.082
2017 Korley FK, Diaz-Arrastia R, Falk HJ, Peters ME, Leoutsakos JS, Roy D, Rao V, Sair HI, Ofoche U, Hall AJ, Akbari F, Van Meter TE, Everett AD, Van Eyk JE, Bechtold KT. Prevalence of Incomplete Functional and Symptomatic Recovery among Patients with Head Injury but Brain Injury Debatable. Journal of Neurotrauma. 34: 1531-1538. PMID 27784200 DOI: 10.1089/Neu.2016.4723  0.082
2023 Margvelani G, Welden JR, Maquera AA, Van Eyk JE, Murray C, Miranda Sardon SC, Stamm S. Influence of FTDP-17 mutants on circular Tau RNAs. Biorxiv : the Preprint Server For Biology. PMID 37786725 DOI: 10.1101/2023.09.08.556913  0.081
2024 Margvelani G, Welden JR, Maquera AA, Van Eyk JE, Murray C, Miranda Sardon SC, Stamm S. Influence of FTDP-17 mutants on circular tau RNAs. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 167036. PMID 38286213 DOI: 10.1016/j.bbadis.2024.167036  0.081
2020 Doustar J, Rentsendorj A, Torbati T, Regis GC, Fuchs DT, Sheyn J, Mirzaei N, Graham SL, Shah PK, Mastali M, Van Eyk JE, Black KL, Gupta VK, Mirzaei M, Koronyo Y, et al. Parallels between retinal and brain pathology and response to immunotherapy in old, late-stage Alzheimer's disease mouse models. Aging Cell. e13246. PMID 33090673 DOI: 10.1111/acel.13246  0.08
2017 Alonso C, Fernández-Ramos D, Varela-Rey M, Martínez-Arranz I, Navasa N, Van Liempd SM, Lavin JL, Mayo R, Ilisso CP, de Juan VG, Iruarrizaga-Lejarreta M, delaCruz-Villar L, Mincholé I, Robinson A, Crespo J, ... ... Van Eyk J, et al. Metabolomic Identification of Subtypes of Nonalcoholic Steatohepatitis. Gastroenterology. PMID 28132890 DOI: 10.1053/J.Gastro.2017.01.015  0.08
2022 Wu CT, Shen M, Du D, Cheng Z, Parker SJ, Lu Y, Van Eyk JE, Yu G, Clarke R, Herrington DM, Wang Y. Cosbin: cosine score-based iterative normalization of biologically diverse samples. Bioinformatics Advances. 2: vbac076. PMID 36330358 DOI: 10.1093/bioadv/vbac076  0.079
2015 Korley FK, Diaz-Arrastia R, Wu AH, Yue JK, Manley GT, Sair HI, Van Eyk J, Everett AD, Okonkwo DO, Valadka A, Gordon WA, Maas A, Mukherjee P, Yuh EL, Lingsma H, et al. Circulating Brain Derived Neurotrophic Factor (BDNF) Has Diagnostic and Prognostic Value in Traumatic Brain Injury. Journal of Neurotrauma. PMID 26159676 DOI: 10.1089/Neu.2015.3949  0.078
2019 Fuller G, Njune Mouapi K, Joung S, Shufelt C, van den Broek I, Lopez M, Dhawan S, Mastali M, Spiegel C, Bairey Merz N, Van Eyk JE, Robinson A. Feasibility of Patient-Centric Remote Dried Prediction, Risk, and Evaluation of Major Adverse Cardiac Events (PRE-MACE) Study. Biodemography and Social Biology. 65: 313-322. PMID 33243027 DOI: 10.1080/19485565.2020.1765735  0.077
2014 Semba RD, Huang H, Lutty GA, Van Eyk JE, Hart GW. The role of O-GlcNAc signaling in the pathogenesis of diabetic retinopathy. Proteomics. Clinical Applications. 8: 218-31. PMID 24550151 DOI: 10.1002/Prca.201300076  0.076
2008 Matt P, Habashi J, Carrel T, Cameron DE, Van Eyk JE, Dietz HC. Recent advances in understanding Marfan syndrome: should we now treat surgical patients with losartan? The Journal of Thoracic and Cardiovascular Surgery. 135: 389-94. PMID 18242274 DOI: 10.1016/J.Jtcvs.2007.08.047  0.075
2023 Rentsendorj A, Raedschelders K, Fuchs DT, Sheyn J, Vaibhav V, Porritt RA, Shi H, Dagvadorj J, de Freitas Germano J, Koronyo Y, Arditi M, Black KL, Gaire BP, Van Eyk JE, Koronyo-Hamaoui M. Osteopontin depletion in macrophages perturbs proteostasis regulating UCHL1-UPS axis and mitochondria-mediated apoptosis. Frontiers in Immunology. 14: 1155935. PMID 37325640 DOI: 10.3389/fimmu.2023.1155935  0.075
2023 Bathon JM, Centola M, Liu X, Jin Z, Ji W, Knowlton NS, Ferraz-Amaro I, Fu Q, Giles JT, Wasko MC, Stein CM, Van Eyk JE. Identification of novel biomarkers for the prediction of subclinical coronary artery atherosclerosis in patients with rheumatoid arthritis: an exploratory analysis. Arthritis Research & Therapy. 25: 213. PMID 37899440 DOI: 10.1186/s13075-023-03196-3  0.074
2007 Matt P, Carrel T, White M, Lefkovits I, Van Eyk J. Proteomics in cardiovascular surgery. The Journal of Thoracic and Cardiovascular Surgery. 133: 210-4. PMID 17198814 DOI: 10.1016/j.jtcvs.2006.09.007  0.073
2008 Van Eyk JE, Dunn MJ. Clinical Proteomics: From Diagnosis to Therapy Clinical Proteomics: From Diagnosis to Therapy. 1-659. DOI: 10.1002/9783527622153  0.073
2019 Mecoli CA, Perin J, Van Eyk JE, Zhu J, Fu Q, Allmon AG, Rao Y, Zeger S, Wigley FM, Hummers LK, Shah AA. Vascular biomarkers and digital ulcerations in systemic sclerosis: results from a randomized controlled trial of oral treprostinil (DISTOL-1). Clinical Rheumatology. PMID 31858338 DOI: 10.1007/S10067-019-04863-0  0.071
2012 Lindsay ME, Schepers D, Bolar NA, Doyle JJ, Gallo E, Fert-Bober J, Kempers MJ, Fishman EK, Chen Y, Myers L, Bjeda D, Oswald G, Elias AF, Levy HP, Anderlid BM, ... ... Van Eyk J, et al. Loss-of-function mutations in TGFB2 cause a syndromic presentation of thoracic aortic aneurysm. Nature Genetics. 44: 922-7. PMID 22772368 DOI: 10.1038/Ng.2349  0.07
2014 Morissette R, Schoenhoff F, Xu Z, Shilane DA, Griswold BF, Chen W, Yang J, Zhu J, Fert-Bober J, Sloper L, Lehman J, Commins N, Van Eyk JE, McDonnell NB. Transforming growth factor-β and inflammation in vascular (type IV) Ehlers-Danlos syndrome. Circulation. Cardiovascular Genetics. 7: 80-8. PMID 24399159 DOI: 10.1161/Circgenetics.113.000280  0.07
2019 Lahiri S, Regis GC, Koronyo Y, Fuchs DT, Sheyn J, Kim EH, Mastali M, Van Eyk JE, Rajput PS, Lyden PD, Black KL, Ely EW, D Jones H, Koronyo-Hamaoui M. Acute neuropathological consequences of short-term mechanical ventilation in wild-type and Alzheimer's disease mice. Critical Care (London, England). 23: 63. PMID 30795776 DOI: 10.1186/S13054-019-2356-2  0.07
2019 Berg AH, Van Eyk J. Which Methods for Determining Glomerular Filtration Rate Most Strongly Associate with Risk of Progression of Kidney Disease? Clinical Chemistry. PMID 30647125 DOI: 10.1373/clinchem.2018.300731  0.068
2012 Stastna M, Van Eyk JE. New and emerging technologies for clinical proteomics. Proteomics. Clinical Applications. 6: 547. PMID 23255386 DOI: 10.1002/prca.201270053  0.068
2010 Ellinor PT, Van Eyk JE. Top advances in functional genomics and translational biology for 2009. Circulation. Cardiovascular Genetics. 3: 106-8. PMID 20160202 DOI: 10.1161/CIRCGENETICS.110.937367  0.068
2008 Tharakan R, Martens L, Van Eyk JE, Graham DR. OMSSAGUI: An open-source user interface component to configure and run the OMSSA search engine. Proteomics. 8: 2376-8. PMID 18563730 DOI: 10.1002/pmic.200701126  0.066
2010 Matt P, Huso DL, Habashi J, Holm T, Doyle J, Schoenhoff F, Liu G, Black J, Van Eyk JE, Dietz HC. Murine model of surgically induced acute aortic dissection type A. The Journal of Thoracic and Cardiovascular Surgery. 139: 1041-7. PMID 19910001 DOI: 10.1016/J.Jtcvs.2009.08.039  0.066
2014 Ganesh SK, Morissette R, Xu Z, Schoenhoff F, Griswold BF, Yang J, Tong L, Yang ML, Hunker K, Sloper L, Kuo S, Raza R, Milewicz DM, Francomano CA, Dietz HC, ... Van Eyk J, et al. Clinical and biochemical profiles suggest fibromuscular dysplasia is a systemic disease with altered TGF-β expression and connective tissue features Faseb Journal. 28: 3313-3324. PMID 24732132 DOI: 10.1096/Fj.14-251207  0.065
2021 Ramani K, Robinson AE, Berlind J, Fan W, Abeynayake A, Binek A, Barbier-Torres L, Noureddin M, Nissen NN, Yildirim Z, Erbay E, Mato JM, Van Eyk JE, Lu SC. S-Adenosylmethionine Inhibits La Ribonucleoprotein Domain Family Member 1 in Murine Liver and Human Liver Cancer Cells. Hepatology (Baltimore, Md.). PMID 34449924 DOI: 10.1002/hep.32130  0.065
2017 Todd Milne G, Sandner P, Lincoln KA, Harrison PC, Chen H, Wang H, Clifford H, Qian HS, Wong D, Sarko C, Fryer R, Richman J, Reinhart GA, Boustany CM, Pullen SS, ... ... Van Eyk JE, et al. Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications : Bamberg, Germany. 23-25 June, 2017. Bmc Pharmacology & Toxicology. 18: 64. PMID 29035170 DOI: 10.1186/s40360-017-0170-5  0.063
2022 Park E, Ito K, Iqbal R, Amigues I, Bokhari S, Van Eyk J, Depender C, Giles JT, Bathon J. Prospective changes in diastolic function in patients with rheumatoid arthritis. Arthritis Research & Therapy. 24: 184. PMID 35932048 DOI: 10.1186/s13075-022-02864-0  0.063
2018 Van Eyk JE, Sobhani K. Precision Medicine. Circulation. 138: 2172-2174. PMID 30571512 DOI: 10.1161/CIRCULATIONAHA.118.036781  0.057
2021 Figueiredo JC, Merin NM, Hamid O, Choi SY, Lemos T, Cozen W, Nguyen N, Finster LJ, Foley J, Darrah J, Gong J, Paquette R, Mita AC, Vescio R, Mehmi I, ... ... Van Eyk J, et al. Longitudinal SARS-CoV-2 mRNA vaccine-induced humoral immune responses in cancer patients. Cancer Research. PMID 34759001 DOI: 10.1158/0008-5472.CAN-21-3554  0.056
2015 Hyun Sohn D, Rhodes C, Onuma K, Zhao X, Sharpe O, Gazitt T, Shiao R, Fert-Bober J, Cheng D, Lahey LJ, Wong HH, Van Eyk J, Robinson WH, Sokolove J. Local joint inflammation and histone citrullination provides a murine model for the transition from preclinical autoimmunity to inflammatory arthritis. Arthritis & Rheumatology (Hoboken, N.J.). PMID 26227989 DOI: 10.1002/art.39283  0.055
2019 Kothari P, Srivastava V, Aggarwal V, Tchernyshyov I, Van Eyk J, Ha T, Robinson DN. Mapping the Biochemical Interactions of the Mechanoresponsive Contractility Controller Biophysical Journal. 116: 119a-120a. DOI: 10.1016/J.Bpj.2018.11.669  0.054
2011 Van Eyk JE. Maximizing the utility of proteomics: an educational series. Circulation. Cardiovascular Genetics. 4: 574. PMID 22010163 DOI: 10.1161/CIRCGENETICS.111.961433  0.051
2020 Ebinger JE, Achamallah N, Ji H, Claggett BL, Sun N, Botting P, Nguyen TT, Luong E, Kim EH, Park E, Liu Y, Rosenberry R, Matusov Y, Zhao S, Pedraza I, ... ... Van Eyk JE, et al. Pre-existing traits associated with Covid-19 illness severity. Plos One. 15: e0236240. PMID 32702044 DOI: 10.1371/Journal.Pone.0236240  0.05
2020 Noval Rivas M, Ebinger JE, Wu M, Sun N, Braun J, Sobhani K, Van Eyk JE, Cheng S, Arditi M. BCG vaccination history associates with decreased SARS-CoV-2 seroprevalence across a diverse cohort of healthcare workers. The Journal of Clinical Investigation. PMID 33211672 DOI: 10.1172/JCI145157  0.048
2019 Korley FK, Goldstick J, Mastali M, Van Eyk JE, Barsan W, Meurer WJ, Sussman J, Falk H, Levine D. Serum NfL (Neurofilament Light Chain) Levels and Incident Stroke in Adults With Diabetes Mellitus. Stroke. STROKEAHA119024941. PMID 31138085 DOI: 10.1161/Strokeaha.119.024941  0.048
2022 Ebinger JE, Joung S, Liu Y, Wu M, Weber B, Claggett B, Botting PG, Sun N, Driver M, Kao YH, Khuu B, Wynter T, Nguyen TT, Alotaibi M, Prostko JC, ... ... Van Eyk JE, et al. Demographic and clinical characteristics associated with variations in antibody response to BNT162b2 COVID-19 vaccination among healthcare workers at an academic medical centre: a longitudinal cohort analysis. Bmj Open. 12: e059994. PMID 35613792 DOI: 10.1136/bmjopen-2021-059994  0.046
2017 Ho AS, Kim S, Tighiouart M, Gudino C, Mita A, Scher KS, Laury A, Prasad R, Shiao SL, Van Eyk JE, Zumsteg ZS. Metastatic Lymph Node Burden and Survival in Oral Cavity Cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 35: 3601-3609. PMID 28880746 DOI: 10.1200/JCO.2016.71.1176  0.045
2012 Murray CI, Van Eyk JE. A twist on quantification: measuring the site occupancy of S-nitrosylation. Circulation Research. 111: 1253-5. PMID 23104874 DOI: 10.1161/CIRCRESAHA.112.278721  0.041
2015 Yan K, Fu Z, Yang C, Zhang K, Jiang S, Lee DH, Heo HY, Zhang Y, Cole RN, Van Eyk JE, Zhou J. Assessing Amide Proton Transfer (APT) MRI Contrast Origins in 9 L Gliosarcoma in the Rat Brain Using Proteomic Analysis. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 17: 479-87. PMID 25622812 DOI: 10.1007/S11307-015-0828-6  0.038
2021 Ebinger JE, Fert-Bober J, Printsev I, Wu M, Sun N, Prostko JC, Frias EC, Stewart JL, Van Eyk JE, Braun JG, Cheng S, Sobhani K. Antibody responses to the BNT162b2 mRNA vaccine in individuals previously infected with SARS-CoV-2. Nature Medicine. PMID 33795870 DOI: 10.1038/s41591-021-01325-6  0.035
2021 Ebinger JE, Botwin GJ, Albert CM, Alotaibi M, Arditi M, Berg AH, Binek A, Botting P, Fert-Bober J, Figueiredo JC, Grein JD, Hasan W, Henglin M, Hussain SK, Jain M, ... ... Van Eyk JE, et al. Seroprevalence of antibodies to SARS-CoV-2 in healthcare workers: a cross-sectional study. Bmj Open. 11: e043584. PMID 33579769 DOI: 10.1136/bmjopen-2020-043584  0.035
2018 Ho AS, Kim S, Tighiouart M, Gudino C, Mita A, Scher KS, Laury A, Prasad R, Shiao SL, Ali N, Patio C, Mallen-St Clair J, Van Eyk JE, Zumsteg ZS. Association of Quantitative Metastatic Lymph Node Burden With Survival in Hypopharyngeal and Laryngeal Cancer. Jama Oncology. 4: 985-989. PMID 29192305 DOI: 10.1001/jamaoncol.2017.3852  0.033
2015 Van Eyk J. Prof. Michael (Mike) J. Dunn--paying forward. Proteomics. Clinical Applications. 8: 476. PMID 25123749 DOI: 10.1002/prca.201470045  0.027
2018 Ho A, Kim S, Tighiouart M, Gudino C, Mita A, Scher K, Epstein J, Ali N, Patio C, Laury A, Prasad R, Thompson H, Strouss A, Mallen-St.Clair J, Shiao S, ... Van Eyk J, et al. Survival Impact of Treatment Interval Delays in Head and Neck Cancer International Journal of Radiation Oncology*Biology*Physics. 100: 1322-1323. DOI: 10.1016/j.ijrobp.2017.12.046  0.024
2021 Ebinger JE, Lan R, Sun N, Wu M, Joung S, Botwin GJ, Botting P, Al-Amili D, Aronow H, Beekley J, Coleman B, Contreras S, Cozen W, Davis J, Debbas P, ... ... Van Eyk JE, et al. Symptomology following mRNA vaccination against SARS-CoV-2. Preventive Medicine. 106860. PMID 34687733 DOI: 10.1016/j.ypmed.2021.106860  0.021
2020 Ho AS, Luu M, Barrios L, Balzer BL, Bose S, Fan X, Walgama E, Mallen-St Clair J, Alam U, Shafqat I, Lin DC, Chen Y, Van Eyk JE, Maghami EG, Braunstein GD, et al. Prognostic Impact of Histologic Grade for Papillary Thyroid Carcinoma. Annals of Surgical Oncology. PMID 32808161 DOI: 10.1245/s10434-020-09023-2  0.021
1992 Vreeken C, Van Eyk J, Loxham M, Visser W. Remedial actions at operating petrochemical sites GéOtechnique. 42: 23-31. DOI: 10.1680/geot.1992.42.1.23  0.02
2009 Matt P, Schoenhoff F, Habashi J, Holm T, Van Erp C, Loch D, Carlson OD, Griswold BF, Fu Q, De Backer J, Loeys B, Huso DL, McDonnell NB, Van Eyk JE, Dietz HC, et al. Circulating transforming growth factor-beta in Marfan syndrome. Circulation. 120: 526-32. PMID 19635970 DOI: 10.1161/Circulationaha.108.841981  0.02
2002 Van Eyk J. Editorial from the Technical Briefs Editor Proteomics. 2: 946. DOI: 10.1002/1615-9861(200208)2:8<946::AID-PROT946>3.0.CO;2-N  0.018
1981 MULHEIRN LJ, Van Eyk J. Microbiological Oxidation of Steroid Hydrocarbons Microbiology. 126: 267-275. DOI: 10.1099/00221287-126-2-267  0.015
2013 Banks R, van Eyk J. Introducing the "personal perspective" series. Proteomics. Clinical Applications. 6: 339. PMID 22927348 DOI: 10.1002/prca.201270033  0.012
2023 Kim Y, Mastali M, Van Eyk JE, Orav EJ, Vissing CR, Day SM, Axelsson Raja A, Russell MW, Zahka K, Lever HM, Pereira AC, Murphy AM, Canter C, Bach RG, Wheeler MT, et al. Transforming Growth Factor-β Analysis of the VANISH Trial Cohort. Circulation. Heart Failure. e010314. PMID 36999957 DOI: 10.1161/CIRCHEARTFAILURE.122.010314  0.01
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