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Amber L. Mosley, Ph.D. - Publications

Affiliations: 
1999-2004 University of Kentucky, Lexington, KY 
 2004-2010 Stowers Institute for Medical Research, Kansas City, Missouri, Kansas City, MO, United States 
 2010- Biochemistry Indiana Univ. School of Medicine 
Area:
Biochemistry, Molecular Biology, Proteomics
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41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Fetian T, McShane BM, Horan NL, Shodja DN, True JD, Mosley AL, Arndt KM. Paf1 complex subunit Rtf1 stimulates H2B ubiquitylation by interacting with the highly conserved N-terminal helix of Rad6. Proceedings of the National Academy of Sciences of the United States of America. 120: e2220041120. PMID 37216505 DOI: 10.1073/pnas.2220041120  0.351
2020 Wu X, Niculite CM, Preda MB, Rossi A, Tebaldi T, Butoi E, White MK, Tudoran OM, Petrusca DN, Jannasch AS, Bone WP, Zong X, Fang F, Burlacu A, Paulsen MT, ... ... Mosley A, et al. Regulation of cellular sterol homeostasis by the oxygen responsive noncoding RNA lincNORS. Nature Communications. 11: 4755. PMID 32958772 DOI: 10.1038/S41467-020-18411-X  0.341
2020 Peck Justice SA, Barron MP, Qi GD, Wijeratne HRS, Victorino JF, Simpson ER, Vilseck JZ, Wijeratne AB, Mosley AL. Mutant thermal proteome profiling for characterization of missense protein variants and their associated phenotypes within the proteome. The Journal of Biological Chemistry. PMID 32878984 DOI: 10.1074/Jbc.Ra120.014576  0.303
2020 Victorino JF, Fox MJ, Smith-Kinnaman WR, Peck Justice SA, Burriss KH, Boyd AK, Zimmerly MA, Chan RR, Hunter GO, Liu Y, Mosley AL. RNA Polymerase II CTD phosphatase Rtr1 fine-tunes transcription termination. Plos Genetics. 16: e1008317. PMID 32187185 DOI: 10.1371/Journal.Pgen.1008317  0.437
2019 Levasseur EM, Yamada K, Piñeros AR, Wu W, Syed F, Orr KS, Anderson-Baucum E, Mastracci TL, Maier B, Mosley AL, Liu Y, Bernal-Mizrachi E, Alonso LC, Scott D, Garcia-Ocaña A, et al. Hypusine biosynthesis in β cells links polyamine metabolism to facultative cellular proliferation to maintain glucose homeostasis. Science Signaling. 12. PMID 31796630 DOI: 10.1126/Scisignal.Aax0715  0.427
2019 Harris MT, Jeffers V, Martynowicz J, True JD, Mosley AL, Sullivan WJ. A novel GCN5b lysine acetyltransferase complex associates with distinct transcription factors in the protozoan parasite Toxoplasma gondii. Molecular and Biochemical Parasitology. 111203. PMID 31381949 DOI: 10.1016/J.Molbiopara.2019.111203  0.423
2019 Burriss KH, Mosley AL. Methods review: Mass spectrometry analysis of RNAPII complexes. Methods (San Diego, Calif.). PMID 30902665 DOI: 10.1016/J.Ymeth.2019.03.013  0.376
2019 Peck SA, Hughes KD, Victorino JF, Mosley AL. Writing a wrong: Coupled RNA polymerase II transcription and RNA quality control. Wiley Interdisciplinary Reviews. Rna. e1529. PMID 30848101 DOI: 10.1002/Wrna.1529  0.355
2019 Kelley MR, Shahda S, Lakhani NJ, O'Neil B, Chu L, Anderson AK, Wan J, Mosley AL, Liu H, Messmann RA. Abstract PR01: A phase I study targeting the APE1/Ref-1 DNA repair-redox signaling protein with the APX3330 inhibitor Molecular Cancer Therapeutics. 18. DOI: 10.1158/1535-7163.Targ-19-Pr01  0.307
2018 Dronamraju R, Kerschner JL, Peck SA, Hepperla AJ, Adams AT, Hughes KD, Aslam S, Yoblinski AR, Davis IJ, Mosley AL, Strahl BD. Casein Kinase II Phosphorylation of Spt6 Enforces Transcriptional Fidelity by Maintaining Spn1-Spt6 Interaction. Cell Reports. 25: 3476-3489.e5. PMID 30566871 DOI: 10.1016/J.Celrep.2018.11.089  0.433
2018 Watkins DS, True JD, Mosley AL, Baucum AJ. Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization. Proteomes. 6. PMID 30562941 DOI: 10.3390/Proteomes6040053  0.338
2017 Gokmen-Polar Y, True JD, Vieth E, Qi GD, Mosley AL, Badve SS. Phosphopeptide mapping of DLC1 in ER+ breast cancer reveals AMOTL2, a key hippo pathway component, as an important target. Journal of Clinical Oncology. 35: 11592-11592. DOI: 10.1200/Jco.2017.35.15_Suppl.11592  0.339
2016 Hunter GO, Fox MJ, Smith-Kinnaman WR, Gogol M, Fleharty B, Mosley AL. The phosphatase Rtr1 regulates global levels of serine 5 RNA Polymerase II C-terminal domain phosphorylation and cotranscriptional histone methylation. Molecular and Cellular Biology. PMID 27247267 DOI: 10.1128/Mcb.00870-15  0.431
2016 Bedard LG, Dronamraju R, Kerschner JL, Hunter GO, Axley ED, Boyd AK, Strahl BD, Mosley AL. Quantitative analysis of dynamic protein interactions during transcription reveals a role for casein kinase II in PAF complex phosphorylation and regulation of H2B monoubiquitylation. The Journal of Biological Chemistry. PMID 27143358 DOI: 10.1074/Jbc.M116.727735  0.374
2016 Fox MJ, Mosley AL. Rrp6: Integrated roles in nuclear RNA metabolism and transcription termination. Wiley Interdisciplinary Reviews. Rna. 7: 91-104. PMID 26612606 DOI: 10.1002/Wrna.1317  0.353
2015 Simon JM, Parker JS, Liu F, Rothbart SB, Ait-Si-Ali S, Strahl BD, Jin J, Davis IJ, Mosley AL, Pattenden SG. A Role for Widely Interspaced Zinc Finger (WIZ) in Retention of the G9a Methyltransferase on Chromatin. The Journal of Biological Chemistry. 290: 26088-102. PMID 26338712 DOI: 10.1074/Jbc.M115.654459  0.328
2015 Maganti AV, Maier B, Tersey SA, Sampley ML, Mosley AL, Özcan S, Pachaiyappan B, Woster PM, Hunter CS, Stein R, Mirmira RG. Transcriptional activity of the islet β cell factor Pdx1 is augmented by lysine methylation catalyzed by the methyltransferase Set7/9. The Journal of Biological Chemistry. 290: 9812-22. PMID 25713082 DOI: 10.1074/Jbc.M114.616219  0.669
2015 Fox MJ, Gao H, Smith-Kinnaman WR, Liu Y, Mosley AL. The exosome component Rrp6 is required for RNA polymerase II termination at specific targets of the Nrd1-Nab3 pathway. Plos Genetics. 11: e1004999. PMID 25680078 DOI: 10.1371/Journal.Pgen.1004999  0.409
2014 Zhang Q, Zhou X, Wu R, Mosley A, Zeng SX, Xing Z, Lu H. The role of IMP dehydrogenase 2 in Inauhzin-induced ribosomal stress. Elife. 3. PMID 25347121 DOI: 10.7554/Elife.03077  0.349
2014 Ni Z, Xu C, Guo X, Hunter GO, Kuznetsova OV, Tempel W, Marcon E, Zhong G, Guo H, Kuo WH, Li J, Young P, Olsen JB, Wan C, Loppnau P, ... ... Mosley AL, et al. RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation. Nature Structural & Molecular Biology. 21: 686-95. PMID 24997600 DOI: 10.1038/Nsmb.2853  0.393
2014 Hsu PL, Yang F, Smith-Kinnaman W, Yang W, Song JE, Mosley AL, Varani G. Rtr1 is a dual specificity phosphatase that dephosphorylates Tyr1 and Ser5 on the RNA polymerase II CTD. Journal of Molecular Biology. 426: 2970-81. PMID 24951832 DOI: 10.1016/J.Jmb.2014.06.010  0.432
2014 Smith-Kinnaman WR, Berna MJ, Hunter GO, True JD, Hsu P, Cabello GI, Fox MJ, Varani G, Mosley AL. The interactome of the atypical phosphatase Rtr1 in Saccharomyces cerevisiae. Molecular Biosystems. 10: 1730-41. PMID 24671508 DOI: 10.1039/C4Mb00109E  0.422
2013 Khanna M, Imasaki T, Chikwana VM, Perez-Miller S, Hunter GO, Mosley A, Takagi Y, Hurley TD. Expression and purification of functional human glycogen synthase-1 (hGYS1) in insect cells. Protein Expression and Purification. 90: 78-83. PMID 23711380 DOI: 10.1016/J.Pep.2013.05.007  0.36
2013 Mosley AL, Hunter GO, Sardiu ME, Smolle M, Workman JL, Florens L, Washburn MP. Quantitative proteomics demonstrates that the RNA polymerase II subunits Rpb4 and Rpb7 dissociate during transcriptional elongation. Molecular & Cellular Proteomics : McP. 12: 1530-8. PMID 23418395 DOI: 10.1074/Mcp.M112.024034  0.667
2012 Chen XF, Lehmann L, Lin JJ, Vashisht A, Schmidt R, Ferrari R, Huang C, McKee R, Mosley A, Plath K, Kurdistani SK, Wohlschlegel J, Carey M. Mediator and SAGA have distinct roles in Pol II preinitiation complex assembly and function. Cell Reports. 2: 1061-7. PMID 23177621 DOI: 10.1016/J.Celrep.2012.10.019  0.409
2012 Zhang DW, Mosley AL, Ramisetty SR, Rodríguez-Molina JB, Washburn MP, Ansari AZ. Ssu72 phosphatase-dependent erasure of phospho-Ser7 marks on the RNA polymerase II C-terminal domain is essential for viability and transcription termination Journal of Biological Chemistry. 287: 8541-8551. PMID 22235117 DOI: 10.1074/Jbc.M111.335687  0.586
2012 Daniels DL, Méndez J, Mosley AL, Ramisetty SR, Murphy N, Benink H, Wood KV, Urh M, Washburn MP. Examining the complexity of human RNA polymerase complexes using HaloTag technology coupled to label free quantitative proteomics. Journal of Proteome Research. 11: 564-75. PMID 22149079 DOI: 10.1021/Pr200459C  0.55
2011 Mosley AL, Sardiu ME, Pattenden SG, Workman JL, Florens L, Washburn MP. Highly reproducible label free quantitative proteomic analysis of RNA polymerase complexes. Molecular & Cellular Proteomics : McP. 10: M110.000687. PMID 21048197 DOI: 10.1074/Mcp.M110.000687  0.639
2010 Fournier ML, Paulson A, Pavelka N, Mosley AL, Gaudenz K, Bradford WD, Glynn E, Li H, Sardiu ME, Fleharty B, Seidel C, Florens L, Washburn MP. Delayed correlation of mRNA and protein expression in rapamycin-treated cells and a role for Ggc1 in cellular sensitivity to rapamycin. Molecular & Cellular Proteomics : McP. 9: 271-84. PMID 19955083 DOI: 10.1074/Mcp.M900415-Mcp200  0.554
2009 Mosley AL, Pattenden SG, Carey M, Venkatesh S, Gilmore JM, Florens L, Workman JL, Washburn MP. Rtr1 is a CTD phosphatase that regulates RNA polymerase II during the transition from serine 5 to serine 2 phosphorylation. Molecular Cell. 34: 168-78. PMID 19394294 DOI: 10.1016/J.Molcel.2009.02.025  0.728
2009 Mosley AL, Florens L, Wen Z, Washburn MP. A label free quantitative proteomic analysis of the Saccharomyces cerevisiae nucleus. Journal of Proteomics. 72: 110-20. PMID 19038371 DOI: 10.1016/J.Jprot.2008.10.008  0.543
2008 Black JC, Mosley A, Kitada T, Washburn M, Carey M. The SIRT2 deacetylase regulates autoacetylation of p300. Molecular Cell. 32: 449-55. PMID 18995842 DOI: 10.1016/J.Molcel.2008.09.018  0.551
2006 Zybailov B, Mosley AL, Sardiu ME, Coleman MK, Florens L, Washburn MP. Statistical analysis of membrane proteome expression changes in Saccharomyces cerevisiae. Journal of Proteome Research. 5: 2339-47. PMID 16944946 DOI: 10.1021/Pr060161N  0.536
2005 Finlin BS, Mosley AL, Crump SM, Correll RN, Ozcan S, Satin J, Andres DA. Regulation of L-type Ca2+ channel activity and insulin secretion by the Rem2 GTPase. The Journal of Biological Chemistry. 280: 41864-71. PMID 15728182 DOI: 10.1074/Jbc.M414261200  0.598
2004 Mosley AL, Ozcan S. The pancreatic duodenal homeobox-1 protein (Pdx-1) interacts with histone deacetylases Hdac-1 and Hdac-2 on low levels of glucose. The Journal of Biological Chemistry. 279: 54241-7. PMID 15496408 DOI: 10.1074/Jbc.M410379200  0.667
2004 Mosley AL, Corbett JA, Ozcan S. Glucose regulation of insulin gene expression requires the recruitment of p300 by the beta-cell-specific transcription factor Pdx-1. Molecular Endocrinology (Baltimore, Md.). 18: 2279-90. PMID 15166251 DOI: 10.1210/Me.2003-0463  0.666
2003 Lakshmanan J, Mosley AL, Ozcan S. Repression of transcription by Rgt1 in the absence of glucose requires Std1 and Mth1. Current Genetics. 44: 19-25. PMID 14508605 DOI: 10.1007/S00294-003-0423-2  0.668
2003 Mosley AL, Ozcan S. Glucose regulates insulin gene transcription by hyperacetylation of histone h4. The Journal of Biological Chemistry. 278: 19660-6. PMID 12665509 DOI: 10.1074/Jbc.M212375200  0.657
2003 Mosley AL, Ozcan S. Adenoviral gene transfer into beta-cell lines. Methods in Molecular Medicine. 83: 73-9. PMID 12619717 DOI: 10.1385/1-59259-377-1:073  0.568
2003 Mosley AL, Lakshmanan J, Aryal BK, Ozcan S. Glucose-mediated phosphorylation converts the transcription factor Rgt1 from a repressor to an activator. The Journal of Biological Chemistry. 278: 10322-7. PMID 12527758 DOI: 10.1074/Jbc.M212802200  0.656
2002 Ozcan S, Mosley AL, Aryal BK. Functional expression and analysis of the pancreatic transcription factor PDX-1 in yeast. Biochemical and Biophysical Research Communications. 295: 724-9. PMID 12099699 DOI: 10.1016/S0006-291X(02)00747-7  0.669
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