| Year |
Citation |
Score |
| 2022 |
Uddin MB, Roy KR, Hill RA, Roy SC, Gu X, Li L, Zhang QJ, You Z, Liu YY. p53 missense mutant G242A subverts natural killer cells in sheltering mouse breast cancer cells against immune rejection. Experimental Cell Research. 417: 113210. PMID 35597298 DOI: 10.1016/j.yexcr.2022.113210 |
0.394 |
|
| 2020 |
Roy KR, Uddin MB, Roy SC, Hill RA, Marshall J, Li YT, Chamcheu JC, Lu H, Liu YY. Gb3-cSrc complex in glycosphingolipid-enriched microdomains contributes to the expression of p53 mutant protein and cancer drug resistance via β-catenin-activated RNA methylation. Faseb Bioadvances. 2: 653-667. PMID 33205006 DOI: 10.1096/fba.2020-00044 |
0.526 |
|
| 2019 |
Khiste SK, Liu Z, Roy KR, Uddin MB, Hosain SB, Gu X, Nazzal S, Hill RA, Liu YY. Ceramide-Rubusoside Nanomicelles, a Potential Therapeutic Approach to Target Cancers Carrying p53 Missense Mutations. Molecular Cancer Therapeutics. PMID 31645443 DOI: 10.1158/1535-7163.Mct-19-0366 |
0.57 |
|
| 2019 |
Chamcheu JC, Roy T, Uddin MB, Banang-Mbeumi S, Chamcheu RN, Walker AL, Liu YY, Huang S. Role and Therapeutic Targeting of the PI3K/Akt/mTOR Signaling Pathway in Skin Cancer: A Review of Current Status and Future Trends on Natural and Synthetic Agents Therapy. Cells. 8. PMID 31370278 DOI: 10.3390/Cells8080803 |
0.355 |
|
| 2019 |
Siddique AB, Ebrahim HY, Akl MR, Ayoub NM, Goda AA, Mohyeldin MM, Nagumalli SK, Hananeh WM, Liu YY, Meyer SA, El Sayed KA. (-)-Oleocanthal Combined with Lapatinib Treatment Synergized against HER-2 Positive Breast Cancer In Vitro and In Vivo. Nutrients. 11. PMID 30781364 DOI: 10.3390/Nu11020412 |
0.419 |
|
| 2018 |
Uddin MB, Roy KR, Hosain SB, Khiste SK, Hill RA, Jois SD, Zhao Y, Tackett AJ, Liu YY. An N-methyladenosine at the transited codon 273 of p53 pre-mRNA promotes the expression of R273H mutant protein and drug resistance of cancer cells. Biochemical Pharmacology. 160: 134-145. PMID 30578766 DOI: 10.1016/J.Bcp.2018.12.014 |
0.553 |
|
| 2017 |
Kanthala SP, Liu YY, Singh S, Sable R, Pallerla S, Jois SD. A peptidomimetic with a chiral switch is an inhibitor of epidermal growth factor receptor heterodimerization. Oncotarget. 8: 74244-74262. PMID 29088782 DOI: 10.18632/Oncotarget.19013 |
0.354 |
|
| 2017 |
Khiste SK, Hosain SB, Dong Y, Uddin MB, Roy KR, Hill RA, Liu Z, Liu YY. Incorporation of Fluorescence Ceramide-Based HPLC Assay for Rapidly and Efficiently Assessing Glucosylceramide Synthase In Vivo. Scientific Reports. 7: 2976. PMID 28592871 DOI: 10.1038/S41598-017-03320-9 |
0.499 |
|
| 2017 |
khiste sK, Liu Z, Liu Y. Abstract 2580: Ceramide-rubusoside nano-micelles restores p53-mediated tumor suppression in p53R248W mutant ovarian cancer cells Cancer Research. 77: 2580-2580. DOI: 10.1158/1538-7445.Am2017-2580 |
0.57 |
|
| 2016 |
Hosain SB, Khiste SK, Uddin MB, Vorubindi V, Ingram C, Zhang S, Hill RA, Gu X, Liu YY. Inhibition of glucosylceramide synthase eliminates the oncogenic function of p53 R273H mutant in the epithelial-mesenchymal transition and induced pluripotency of colon cancer cells. Oncotarget. PMID 27517620 DOI: 10.18632/Oncotarget.11169 |
0.584 |
|
| 2016 |
Hosain SB, Khiste SK, Uddin MB, Vorubindi V, Ingram C, Zhang S, Hill RA, Gu X, Liu YY. A recombinantly tailored β-defensin that displays intensive macropinocytosis-mediated uptake exerting potent efficacy against K-Ras mutant pancreatic cancer. Oncotarget. PMID 27517152 DOI: 10.18632/oncotarget.11170 |
0.506 |
|
| 2016 |
Du F, Li Y, Zhang W, Kale SP, McFerrin H, Davenport I, Wang G, Skripnikova E, Li XL, Bowen NJ, McDaniels LB, Meng YX, Polk P, Liu YY, Zhang QJ. Highly and moderately aggressive mouse ovarian cancer cell lines exhibit differential gene expression. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. PMID 26935058 DOI: 10.1007/S13277-015-4518-4 |
0.452 |
|
| 2015 |
Liu Y, Liu Z, Khiste SK, Hosain SB. Abstract LB-A19: Ceramide-Rubusoside, an Ultrasmall Nanomicells Effectively Restores p53 Expression in the Missense Mutant Cancer Cells Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-Lb-A19 |
0.57 |
|
| 2014 |
Patwardhan GA, Hosain SB, Liu DX, Khiste SK, Zhao Y, Bielawski J, Jazwinski SM, Liu YY. Ceramide modulates pre-mRNA splicing to restore the expression of wild-type tumor suppressor p53 in deletion-mutant cancer cells. Biochimica Et Biophysica Acta. 1841: 1571-80. PMID 25195822 DOI: 10.1016/J.Bbalip.2014.08.017 |
0.768 |
|
| 2014 |
Mahdavian E, Palyok P, Adelmund S, Williams-Hart T, Furmanski BD, Kim YJ, Gu Y, Barzegar M, Wu Y, Bhinge KN, Kolluru GK, Quick Q, Liu YY, Kevil CG, Salvatore BA, et al. Biological activities of fusarochromanone: a potent anti-cancer agent. Bmc Research Notes. 7: 601. PMID 25187308 DOI: 10.1186/1756-0500-7-601 |
0.341 |
|
| 2014 |
Sallam AA, Mohyeldin MM, Foudah AI, Akl MR, Nazzal S, Meyer SA, Liu YY, El Sayed KA. Marine natural products-inspired phenylmethylene hydantoins with potent in vitro and in vivo antitumor activities via suppression of Brk and FAK signaling. Organic & Biomolecular Chemistry. 12: 5295-303. PMID 24927150 DOI: 10.1039/C4Ob00553H |
0.496 |
|
| 2014 |
Akl MR, Ayoub NM, Mohyeldin MM, Busnena BA, Foudah AI, Liu YY, Sayed KA. Olive phenolics as c-Met inhibitors: (-)-Oleocanthal attenuates cell proliferation, invasiveness, and tumor growth in breast cancer models. Plos One. 9: e97622. PMID 24849787 DOI: 10.1371/Journal.Pone.0097622 |
0.477 |
|
| 2014 |
Ponnapakam AP, Liu J, Bhinge KN, Drew BA, Wang TL, Antoon JW, Nguyen TT, Dupart PS, Wang Y, Zhao M, Liu YY, Foroozesh M, Beckman BS. 3-Ketone-4,6-diene ceramide analogs exclusively induce apoptosis in chemo-resistant cancer cells. Bioorganic & Medicinal Chemistry. 22: 1412-20. PMID 24457089 DOI: 10.1016/J.Bmc.2013.12.065 |
0.452 |
|
| 2013 |
Gupta V, Liu YY. New Insights on Glucosylceramide Synthase in Cancer Drug Resistance and Myelosuppression. Biochemistry & Pharmacology : Open Access. 2. PMID 25401049 DOI: 10.4172/2167-0501.1000120 |
0.361 |
|
| 2013 |
Liu YY, Hill RA, Li YT. Ceramide glycosylation catalyzed by glucosylceramide synthase and cancer drug resistance. Advances in Cancer Research. 117: 59-89. PMID 23290777 DOI: 10.1016/B978-0-12-394274-6.00003-0 |
0.608 |
|
| 2013 |
Liu Y, Patwardhan GA. Abstract 3199: Ceramide restores the expression of wild-type p53 tumor suppressor in mRNA splicing through PP1 and ASF/SF2. Cancer Research. 73: 3199-3199. DOI: 10.1158/1538-7445.Am2013-3199 |
0.764 |
|
| 2012 |
Gupta V, Bhinge KN, Hosain SB, Xiong K, Gu X, Shi R, Ho MY, Khoo KH, Li SC, Li YT, Ambudkar SV, Jazwinski SM, Liu YY. Ceramide glycosylation by glucosylceramide synthase selectively maintains the properties of breast cancer stem cells. The Journal of Biological Chemistry. 287: 37195-205. PMID 22936806 DOI: 10.1074/Jbc.M112.396390 |
0.424 |
|
| 2012 |
Bhinge KN, Gupta V, Hosain SB, Satyanarayanajois SD, Meyer SA, Blaylock B, Zhang QJ, Liu YY. The opposite effects of doxorubicin on bone marrow stem cells versus breast cancer stem cells depend on glucosylceramide synthase. The International Journal of Biochemistry & Cell Biology. 44: 1770-8. PMID 22728310 DOI: 10.1016/J.Biocel.2012.06.010 |
0.443 |
|
| 2012 |
Yang CL, Liu YY, Ma YG, Xue YX, Liu DG, Ren Y, Liu XB, Li Y, Li Z. Curcumin blocks small cell lung cancer cells migration, invasion, angiogenesis, cell cycle and neoplasia through Janus kinase-STAT3 signalling pathway. Plos One. 7: e37960. PMID 22662257 DOI: 10.1371/journal.pone.0037960 |
0.318 |
|
| 2012 |
Siddiqui A, Gupta V, Liu YY, Nazzal S. Doxorubicin and MBO-asGCS oligonucleotide loaded lipid nanoparticles overcome multidrug resistance in adriamycin resistant ovarian cancer cells (NCI/ADR-RES). International Journal of Pharmaceutics. 431: 222-9. PMID 22562053 DOI: 10.1016/J.Ijpharm.2012.04.050 |
0.385 |
|
| 2011 |
Liu YY. Resuscitating wild-type p53 expression by disrupting ceramide glycosylation: a novel approach to target mutant p53 tumors. Cancer Research. 71: 6295-9. PMID 21972148 DOI: 10.1158/0008-5472.Can-11-0700 |
0.511 |
|
| 2011 |
Liu YY, Patwardhan GA, Xie P, Gu X, Giuliano AE, Cabot MC. Glucosylceramide synthase, a factor in modulating drug resistance, is overexpressed in metastatic breast carcinoma International Journal of Oncology. 39: 425-431. PMID 21617856 DOI: 10.3892/Ijo.2011.1052 |
0.733 |
|
| 2011 |
Gupta V, Zhang QJ, Liu YY. Evaluation of anticancer agents using flow cytometry analysis of cancer stem cells. Methods in Molecular Biology (Clifton, N.J.). 716: 179-91. PMID 21318907 DOI: 10.1007/978-1-61779-012-6_11 |
0.46 |
|
| 2011 |
Liu YY, Patwardhan GA, Bhinge K, Gupta V, Gu X, Jazwinski SM. Suppression of glucosylceramide synthase restores p53-dependent apoptosis in mutant p53 cancer cells. Cancer Research. 71: 2276-85. PMID 21278235 DOI: 10.1158/0008-5472.Can-10-3107 |
0.767 |
|
| 2011 |
Wang F, Liu J, Robbins D, Morris K, Sit A, Liu YY, Zhao Y. Mutant p53 exhibits trivial effects on mitochondrial functions which can be reactivated by ellipticine in lymphoma cells. Apoptosis : An International Journal On Programmed Cell Death. 16: 301-10. PMID 21107702 DOI: 10.1007/S10495-010-0559-8 |
0.479 |
|
| 2011 |
Patwardhan GA, Liu YY. Sphingolipids and expression regulation of genes in cancer. Progress in Lipid Research. 50: 104-14. PMID 20970453 DOI: 10.1016/J.Plipres.2010.10.003 |
0.751 |
|
| 2010 |
Siddiqui A, Patwardhan GA, Liu YY, Nazzal S. Mixed backbone antisense glucosylceramide synthase oligonucleotide (MBO-asGCS) loaded solid lipid nanoparticles: in vitro characterization and reversal of multidrug resistance in NCI/ADR-RES cells. International Journal of Pharmaceutics. 400: 251-9. PMID 20816930 DOI: 10.1016/J.Ijpharm.2010.08.044 |
0.697 |
|
| 2010 |
Liu YY, Gupta V, Patwardhan GA, Bhinge K, Zhao Y, Bao J, Mehendale H, Cabot MC, Li YT, Jazwinski SM. Glucosylceramide synthase upregulates MDR1 expression in the regulation of cancer drug resistance through cSrc and beta-catenin signaling. Molecular Cancer. 9: 145. PMID 20540746 DOI: 10.1186/1476-4598-9-145 |
0.749 |
|
| 2010 |
Chapman JV, Gouazé-Andersson V, Messner MC, Flowers M, Karimi R, Kester M, Barth BM, Liu X, Liu YY, Giuliano AE, Cabot MC. Metabolism of short-chain ceramide by human cancer cells--implications for therapeutic approaches. Biochemical Pharmacology. 80: 308-15. PMID 20385104 DOI: 10.1016/J.Bcp.2010.04.001 |
0.44 |
|
| 2010 |
Patwardhan G, Gupta V, Huang J, Gu X, Liu YY. Direct assessment of P-glycoprotein efflux to determine tumor response to chemotherapy. Biochemical Pharmacology. 80: 72-9. PMID 20298675 DOI: 10.1016/J.Bcp.2010.03.010 |
0.777 |
|
| 2010 |
Gupta V, Patwardhan GA, Zhang QJ, Cabot MC, Jazwinski SM, Liu YY. Direct quantitative determination of ceramide glycosylation in vivo: a new approach to evaluate cellular enzyme activity of glucosylceramide synthase. Journal of Lipid Research. 51: 866-74. PMID 19826105 DOI: 10.1194/Jlr.D002949 |
0.71 |
|
| 2010 |
Patwardhan GA, Gupta V, Hsia S, Gu X, Jazwinski M, Liu Y. Abstract 2569: Disruption of ceramide glycosylation restores p53-dependent apoptosis in p53 mutant drug-resistant cancer cells: Alternative splicing determines the feature of p53 activity Cancer Research. 70: 2569-2569. DOI: 10.1158/1538-7445.Am10-2569 |
0.777 |
|
| 2009 |
Patwardhan GA, Zhang QJ, Yin D, Gupta V, Bao J, Senkal CE, Ogretmen B, Cabot MC, Shah GV, Sylvester PW, Jazwinski SM, Liu YY. A new mixed-backbone oligonucleotide against glucosylceramide synthase sensitizes multidrug-resistant tumors to apoptosis. Plos One. 4: e6938. PMID 19742320 DOI: 10.1371/Journal.Pone.0006938 |
0.764 |
|
| 2009 |
Li XL, Liu YY, Knight D, Odaka Y, Mathis JM, Shi R, Glass J, Zhang QJ. Effect of B7.1 costimulation on T-cell based immunity against TAP-negative cancer can be facilitated by TAP1 expression. Plos One. 4: e6385. PMID 19629186 DOI: 10.1371/Journal.Pone.0006385 |
0.396 |
|
| 2008 |
Li XL, Zhang DQ, Wang D, Knight DS, Yin L, Bao J, Liu YY, Glass J, Mathis JM, Zhang QJ. In vivo survivors of transformed mouse ovarian surface epithelial cells display diverse phenotypes for gene expression and tumorigenicity. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 29: 359-70. PMID 19052485 DOI: 10.1159/000178981 |
0.349 |
|
| 2008 |
Wang H, Maurer BJ, Liu YY, Wang E, Allegood JC, Kelly S, Symolon H, Liu Y, Merrill AH, Gouazé-Andersson V, Yu JY, Giuliano AE, Cabot MC. N-(4-Hydroxyphenyl)retinamide increases dihydroceramide and synergizes with dimethylsphingosine to enhance cancer cell killing. Molecular Cancer Therapeutics. 7: 2967-76. PMID 18790777 DOI: 10.1158/1535-7163.Mct-08-0549 |
0.463 |
|
| 2008 |
Liu YY, Yu JY, Yin D, Patwardhan GA, Gupta V, Hirabayashi Y, Holleran WM, Giuliano AE, Jazwinski SM, Gouaze-Andersson V, Consoli DP, Cabot MC. A role for ceramide in driving cancer cell resistance to doxorubicin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 2541-51. PMID 18245173 DOI: 10.1096/Fj.07-092981 |
0.763 |
|
| 2005 |
Gouazé V, Liu YY, Prickett CS, Yu JY, Giuliano AE, Cabot MC. Glucosylceramide synthase blockade down-regulates P-glycoprotein and resensitizes multidrug-resistant breast cancer cells to anticancer drugs. Cancer Research. 65: 3861-7. PMID 15867385 DOI: 10.1158/0008-5472.Can-04-2329 |
0.576 |
|
| 2004 |
Gouazé V, Yu JY, Bleicher RJ, Han TY, Liu YY, Wang H, Gottesman MM, Bitterman A, Giuliano AE, Cabot MC. Overexpression of glucosylceramide synthase and P-glycoprotein in cancer cells selected for resistance to natural product chemotherapy. Molecular Cancer Therapeutics. 3: 633-9. PMID 15141021 |
0.471 |
|
| 2004 |
Liu YY, Han TY, Yu JY, Bitterman A, Le A, Giuliano AE, Cabot MC. Oligonucleotides blocking glucosylceramide synthase expression selectively reverse drug resistance in cancer cells. Journal of Lipid Research. 45: 933-40. PMID 14967819 DOI: 10.1194/Jlr.M300486-Jlr200 |
0.579 |
|
| 2004 |
Liu YY, Cabot MC. Development of a mammalian Tet-on expression cell line: glucosylceramide synthase regulates TNF-alpha-induced apoptosis. Methods in Molecular Biology (Clifton, N.J.). 249: 177-92. PMID 14573900 DOI: 10.1385/1-59259-667-3:177 |
0.321 |
|
| 2001 |
Liu Y, Han T, Giuliano AE, Cabot MC. Ceramide glycosylation potentiates cellular multidrug resistance The Faseb Journal. 15: 719-730. PMID 11259390 DOI: 10.1096/Fj.00-0223Com |
0.533 |
|
| 1999 |
Liu Y, Han T, Giuliano AE, Ichikawa S, Hirabayashi Y, Cabot MC. Glycosylation of Ceramide Potentiates Cellular Resistance to Tumor Necrosis Factor-α-Induced Apoptosis Experimental Cell Research. 252: 464-470. PMID 10527636 DOI: 10.1006/Excr.1999.4649 |
0.427 |
|
| 1999 |
Liu Y, Han T, Giuliano AE, Cabot MC. Expression of Glucosylceramide Synthase, Converting Ceramide to Glucosylceramide, Confers Adriamycin Resistance in Human Breast Cancer Cells Journal of Biological Chemistry. 274: 1140-1146. PMID 9873062 DOI: 10.1074/Jbc.274.2.1140 |
0.561 |
|
| 1998 |
Lavie Y, Zhang ZC, Cao HT, Han TY, Jones RC, Liu YY, Jarman M, Hardcastle IR, Giuliano AE, Cabot MC. Tamoxifen induces selective membrane association of protein kinase C epsilon in MCF-7 human breast cancer cells International Journal of Cancer. 77: 928-932. PMID 9714066 DOI: 10.1002/(Sici)1097-0215(19980911)77:6<928::Aid-Ijc22>3.0.Co;2-W |
0.416 |
|
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