| Year |
Citation |
Score |
| 2023 |
De Lorenzo F, Lüningschrör P, Nam J, Beckett L, Pilotto F, Galli E, Lindholm P, Rüdt von Collenberg C, Tii Mungwa S, Jablonka S, Kauder J, Thau-Habermann N, Petri S, Lindholm D, Saxena S, ... Sendtner M, et al. CDNF rescues motor neurons in models of amyotrophic lateral sclerosis by targeting endoplasmic reticulum stress. Brain : a Journal of Neurology. PMID 36928391 DOI: 10.1093/brain/awad087 |
0.422 |
|
| 2023 |
Hennlein L, Ghanawi H, Gerstner F, Palominos García E, Yildirim E, Saal-Bauernschubert L, Moradi M, Deng C, Klein T, Appenzeller S, Sauer M, Briese M, Simon C, Sendtner M, Jablonka S. Plastin 3 rescues cell surface translocation and activation of TrkB in spinal muscular atrophy. The Journal of Cell Biology. 222. PMID 36607273 DOI: 10.1083/jcb.202204113 |
0.467 |
|
| 2022 |
Franco-Espin J, Gatius A, Armengol JÁ, Arumugam S, Moradi M, Sendtner M, Calderó J, Tabares L. SMN Is Physiologically Downregulated at Wild-Type Motor Nerve Terminals but Aggregates Together with Neurofilaments in SMA Mouse Models. Biomolecules. 12. PMID 36291733 DOI: 10.3390/biom12101524 |
0.471 |
|
| 2022 |
Deng C, Reinhard S, Hennlein L, Eilts J, Sachs S, Doose S, Jablonka S, Sauer M, Moradi M, Sendtner M. Impaired dynamic interaction of axonal endoplasmic reticulum and ribosomes contributes to defective stimulus-response in spinal muscular atrophy. Translational Neurodegeneration. 11: 31. PMID 35650592 DOI: 10.1186/s40035-022-00304-2 |
0.422 |
|
| 2020 |
Lüningschrör P, Slotta C, Heimann P, Briese M, Weikert UM, Massih B, Appenzeller S, Sendtner M, Kaltschmidt C, Kaltschmidt B. Absence of Plekhg5 Results in Myelin Infoldings Corresponding to an Impaired Schwann Cell Autophagy, and a Reduced T-Cell Infiltration Into Peripheral Nerves. Frontiers in Cellular Neuroscience. 14: 185. PMID 32733205 DOI: 10.3389/Fncel.2020.00185 |
0.437 |
|
| 2020 |
Briese M, Saal-Bauernschubert L, Lüningschrör P, Moradi M, Dombert B, Surrey V, Appenzeller S, Deng C, Jablonka S, Sendtner M. Loss of Tdp-43 disrupts the axonal transcriptome of motoneurons accompanied by impaired axonal translation and mitochondria function. Acta Neuropathologica Communications. 8: 116. PMID 32709255 DOI: 10.1186/S40478-020-00987-6 |
0.458 |
|
| 2020 |
Andreska T, Rauskolb S, Scheffler N, Lüningschrör P, Sasi M, Signoret-Genest J, Behringer M, Blum R, Sauer M, Tovote P, Sendtner M. Induction of BDNF expression in layer II/III and layer V neurons of the motor cortex is essential for motor learning. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32651187 DOI: 10.1523/Jneurosci.0288-20.2020 |
0.47 |
|
| 2020 |
Andreska T, Lüningschrör P, Sendtner M. Regulation of TrkB cell surface expression-a mechanism for modulation of neuronal responsiveness to brain-derived neurotrophic factor. Cell and Tissue Research. PMID 32556728 DOI: 10.1007/S00441-020-03224-7 |
0.477 |
|
| 2020 |
Lüningschrör P, Werner G, Stroobants S, Kakuta S, Dombert B, Sinske D, Wanner R, Lüllmann-Rauch R, Wefers B, Wurst W, D'Hooge R, Uchiyama Y, Sendtner M, Haass C, Saftig P, et al. The FTLD Risk Factor TMEM106B Regulates the Transport of Lysosomes at the Axon Initial Segment of Motoneurons. Cell Reports. 30: 3506-3519.e6. PMID 32160553 DOI: 10.1016/J.Celrep.2020.02.060 |
0.478 |
|
| 2019 |
von Collenberg CR, Schmitt D, Rülicke T, Sendtner M, Blum R, Buchner E. Essential role of the mouse synapse associated protein Syap1 in circuits for spontaneous motor activity and rotarod balance. Biology Open. PMID 31118165 DOI: 10.1242/Bio.042366 |
0.466 |
|
| 2019 |
Brenner D, Sieverding K, Bruno C, Lüningschrör P, Buck E, Mungwa S, Fischer L, Brockmann SJ, Ulmer J, Bliederhäuser C, Philibert CE, Satoh T, Akira S, Boillée S, Mayer B, ... Sendtner M, et al. Heterozygous loss has opposing effects in early and late stages of ALS in mice. The Journal of Experimental Medicine. PMID 30635357 DOI: 10.1084/Jem.20180729 |
0.35 |
|
| 2018 |
Merk DJ, Ohli J, Merk ND, Thatikonda V, Morrissy S, Schoof M, Schmid SN, Harrison L, Filser S, Ahlfeld J, Erkek S, Raithatha K, Andreska T, Weißhaar M, Launspach M, ... ... Sendtner M, et al. Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma. Developmental Cell. PMID 29551561 DOI: 10.1016/J.Devcel.2018.02.012 |
0.327 |
|
| 2018 |
Briese M, Saal-Bauernschubert L, Ji C, Moradi M, Ghanawi H, Uhl M, Appenzeller S, Backofen R, Sendtner M. hnRNP R and its main interactor, the noncoding RNA 7SK, coregulate the axonal transcriptome of motoneurons. Proceedings of the National Academy of Sciences of the United States of America. PMID 29507242 DOI: 10.1073/Pnas.1721670115 |
0.357 |
|
| 2018 |
Brenner D, Yilmaz R, Müller K, Grehl T, Petri S, Meyer T, Grosskreutz J, Weydt P, Ruf W, Neuwirth C, Weber M, Pinto S, Claeys KG, Schrank B, Jordan B, ... ... Sendtner M, et al. Hot-spot KIF5A mutations cause familial ALS. Brain : a Journal of Neurology. PMID 29342275 DOI: 10.1093/Brain/Awx370 |
0.322 |
|
| 2017 |
Lüningschrör P, Binotti B, Dombert B, Heimann P, Perez-Lara A, Slotta C, Thau-Habermann N, R von Collenberg C, Karl F, Damme M, Horowitz A, Maystadt I, Füchtbauer A, Füchtbauer EM, Jablonka S, ... ... Sendtner M, et al. Plekhg5-regulated autophagy of synaptic vesicles reveals a pathogenic mechanism in motoneuron disease. Nature Communications. 8: 678. PMID 29084947 DOI: 10.1038/S41467-017-00689-Z |
0.348 |
|
| 2017 |
Saal-Bauernschubert L, Briese M, Sendtner M. Optimized Whole Transcriptome Profiling of Motor Axons. Methods in Molecular Biology (Clifton, N.J.). 1654: 231-241. PMID 28986794 DOI: 10.1007/978-1-4939-7231-9_16 |
0.395 |
|
| 2017 |
Jablonka S, Sendtner M. Developmental regulation of SMN expression: pathophysiological implications and perspectives for therapy development in spinal muscular atrophy. Gene Therapy. 24: 506-513. PMID 28556834 DOI: 10.1038/Gt.2017.46 |
0.406 |
|
| 2017 |
Moradi M, Sivadasan R, Saal L, Lüningschrör P, Dombert B, Rathod RJ, Dieterich DC, Blum R, Sendtner M. Differential roles of α-, β-, and γ-actin in axon growth and collateral branch formation in motoneurons. The Journal of Cell Biology. PMID 28246119 DOI: 10.1083/Jcb.201604117 |
0.342 |
|
| 2016 |
Groh J, Friedman HC, Orel N, Ip CW, Fischer S, Spahn I, Schäffner E, Hörner M, Stadler D, Buttmann M, Varallyay C, Solymosi L, Sendtner M, Peterson AC, Martini R. Pathogenic inflammation in the CNS of mice carrying human PLP1 mutations. Human Molecular Genetics. 25: 4686-4702. PMID 28173160 DOI: 10.1093/Hmg/Ddw296 |
0.401 |
|
| 2016 |
Jesse CM, Bushuven E, Tripathi P, Chandrasekar A, Simon CM, Drepper C, Yamoah A, Dreser A, Katona I, Johann S, Beyer C, Wagner S, Grond M, Nikolin S, Anink J, ... ... Sendtner M, et al. ALS-associated endoplasmic reticulum proteins in denervated skeletal muscle: Implications for motor neuron disease pathology. Brain Pathology (Zurich, Switzerland). PMID 27790792 DOI: 10.1111/Bpa.12453 |
0.324 |
|
| 2016 |
Sivadasan R, Hornburg D, Drepper C, Frank N, Jablonka S, Hansel A, Lojewski X, Sterneckert J, Hermann A, Shaw PJ, Ince PG, Mann M, Meissner F, Sendtner M. C9ORF72 interaction with cofilin modulates actin dynamics in motor neurons. Nature Neuroscience. PMID 27723745 DOI: 10.1038/Nn.4407 |
0.452 |
|
| 2016 |
Kenna KP, van Doormaal PT, Dekker AM, Ticozzi N, Kenna BJ, Diekstra FP, van Rheenen W, van Eijk KR, Jones AR, Keagle P, Shatunov A, Sproviero W, Smith BN, van Es MA, Topp SD, ... ... Sendtner M, et al. NEK1 variants confer susceptibility to amyotrophic lateral sclerosis. Nature Genetics. PMID 27455347 DOI: 10.1038/Ng.3626 |
0.315 |
|
| 2016 |
Schmitt D, Funk N, Blum R, Asan E, Andersen L, Rülicke T, Sendtner M, Buchner E. Initial characterization of a Syap1 knock-out mouse and distribution of Syap1 in mouse brain and cultured motoneurons. Histochemistry and Cell Biology. PMID 27344443 DOI: 10.1007/S00418-016-1457-0 |
0.401 |
|
| 2016 |
Rauskolb S, Dombert B, Sendtner M. Insulin-like growth factor 1 in diabetic neuropathy and amyotrophic lateral sclerosis. Neurobiology of Disease. PMID 27142684 DOI: 10.1016/J.Nbd.2016.04.007 |
0.423 |
|
| 2016 |
Yadav P, Selvaraj BT, Bender FL, Behringer M, Moradi M, Sivadasan R, Dombert B, Blum R, Asan E, Sauer M, Julien JP, Sendtner M. Neurofilament depletion improves microtubule dynamics via modulation of Stat3/stathmin signaling. Acta Neuropathologica. PMID 27021905 DOI: 10.1007/S00401-016-1564-Y |
0.426 |
|
| 2015 |
Simon CM, Rauskolb S, Gunnersen JM, Holtmann B, Drepper C, Dombert B, Braga M, Wiese S, Jablonka S, Pühringer D, Zielasek J, Hoeflich A, Silani V, Wolf E, Kneitz S, ... ... Sendtner M, et al. Dysregulated IGFBP5 expression causes axon degeneration and motoneuron loss in diabetic neuropathy. Acta Neuropathologica. PMID 26025657 DOI: 10.1007/S00401-015-1446-8 |
0.413 |
|
| 2015 |
Wirth B, Barkats M, Martinat C, Sendtner M, Gillingwater TH. Moving towards treatments for spinal muscular atrophy: hopes and limits. Expert Opinion On Emerging Drugs. 1-4. PMID 25920617 DOI: 10.1517/14728214.2015.1041375 |
0.314 |
|
| 2015 |
Blázquez C, Chiarlone A, Bellocchio L, Resel E, Pruunsild P, García-Rincón D, Sendtner M, Timmusk T, Lutz B, Galve-Roperh I, Guzmán M. The CB1 cannabinoid receptor signals striatal neuroprotection via a PI3K/Akt/mTORC1/BDNF pathway. Cell Death and Differentiation. PMID 25698444 DOI: 10.1038/Cdd.2015.11 |
0.351 |
|
| 2015 |
Linker RA, Lee DH, Flach AC, Litke T, van den Brandt J, Reichardt HM, Lingner T, Bommhardt U, Sendtner M, Gold R, Flügel A, Lühder F. Thymocyte-derived BDNF influences T-cell maturation at the DN3/DN4 transition stage. European Journal of Immunology. 45: 1326-38. PMID 25627579 DOI: 10.1002/Eji.201444985 |
0.327 |
|
| 2014 |
Dombert B, Sivadasan R, Simon CM, Jablonka S, Sendtner M. Presynaptic localization of Smn and hnRNP R in axon terminals of embryonic and postnatal mouse motoneurons. Plos One. 9: e110846. PMID 25338097 DOI: 10.1371/Journal.Pone.0110846 |
0.406 |
|
| 2014 |
Saal L, Briese M, Kneitz S, Glinka M, Sendtner M. Subcellular transcriptome alterations in a cell culture model of spinal muscular atrophy point to widespread defects in axonal growth and presynaptic differentiation. Rna (New York, N.Y.). 20: 1789-802. PMID 25246652 DOI: 10.1261/Rna.047373.114 |
0.419 |
|
| 2014 |
Hornburg D, Drepper C, Butter F, Meissner F, Sendtner M, Mann M. Deep proteomic evaluation of primary and cell line motoneuron disease models delineates major differences in neuronal characteristics. Molecular & Cellular Proteomics : McP. 13: 3410-20. PMID 25193168 DOI: 10.1074/Mcp.M113.037291 |
0.397 |
|
| 2014 |
Götz R, Sendtner M. Cooperation of tyrosine kinase receptor TrkB and epidermal growth factor receptor signaling enhances migration and dispersal of lung tumor cells. Plos One. 9: e100944. PMID 24959744 DOI: 10.1371/Journal.Pone.0100944 |
0.316 |
|
| 2014 |
Johnson JO, Pioro EP, Boehringer A, Chia R, Feit H, Renton AE, Pliner HA, Abramzon Y, Marangi G, Winborn BJ, Gibbs JR, Nalls MA, Morgan S, Shoai M, Hardy J, ... ... Sendtner M, et al. Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis. Nature Neuroscience. 17: 664-6. PMID 24686783 DOI: 10.1038/Nn.3688 |
0.378 |
|
| 2014 |
See K, Yadav P, Giegerich M, Cheong PS, Graf M, Vyas H, Lee SG, Mathavan S, Fischer U, Sendtner M, Winkler C. SMN deficiency alters Nrxn2 expression and splicing in zebrafish and mouse models of spinal muscular atrophy. Human Molecular Genetics. 23: 1754-70. PMID 24218366 DOI: 10.1093/Hmg/Ddt567 |
0.506 |
|
| 2014 |
Jablonka S, Dombert B, Asan E, Sendtner M. Mechanisms for axon maintenance and plasticity in motoneurons: alterations in motoneuron disease. Journal of Anatomy. 224: 3-14. PMID 24007389 DOI: 10.1111/Joa.12097 |
0.439 |
|
| 2013 |
Modi KK, Sendtner M, Pahan K. Up-regulation of ciliary neurotrophic factor in astrocytes by aspirin: implications for remyelination in multiple sclerosis. The Journal of Biological Chemistry. 288: 18533-45. PMID 23653362 DOI: 10.1074/Jbc.M112.447268 |
0.351 |
|
| 2013 |
Selvaraj BT, Sendtner M. CNTF, STAT3 and new therapies for axonal degeneration: what are they and what can they do? Expert Review of Neurotherapeutics. 13: 239-41. PMID 23448212 DOI: 10.1586/Ern.13.9 |
0.309 |
|
| 2013 |
Puehringer D, Orel N, Lüningschrör P, Subramanian N, Herrmann T, Chao MV, Sendtner M. EGF transactivation of Trk receptors regulates the migration of newborn cortical neurons. Nature Neuroscience. 16: 407-15. PMID 23416450 DOI: 10.1038/Nn.3333 |
0.377 |
|
| 2012 |
Selvaraj BT, Frank N, Bender FL, Asan E, Sendtner M. Local axonal function of STAT3 rescues axon degeneration in the pmn model of motoneuron disease. The Journal of Cell Biology. 199: 437-51. PMID 23109669 DOI: 10.1083/Jcb.201203109 |
0.41 |
|
| 2012 |
Gresle MM, Alexandrou E, Wu Q, Egan G, Jokubaitis V, Ayers M, Jonas A, Doherty W, Friedhuber A, Shaw G, Sendtner M, Emery B, Kilpatrick T, Butzkueven H. Leukemia inhibitory factor protects axons in experimental autoimmune encephalomyelitis via an oligodendrocyte-independent mechanism. Plos One. 7: e47379. PMID 23077604 DOI: 10.1371/Journal.Pone.0047379 |
0.421 |
|
| 2012 |
Saenger S, Holtmann B, Nilges MR, Schroeder S, Hoeflich A, Kletzl H, Spooren W, Ostrowitzki S, Hanania T, Sendtner M, Metzger F. Functional improvement in mouse models of familial amyotrophic lateral sclerosis by PEGylated insulin-like growth factor I treatment depends on disease severity. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 13: 418-29. PMID 22871074 DOI: 10.3109/17482968.2012.679944 |
0.39 |
|
| 2012 |
Rathod R, Havlicek S, Frank N, Blum R, Sendtner M. Laminin induced local axonal translation of β-actin mRNA is impaired in SMN-deficient motoneurons. Histochemistry and Cell Biology. 138: 737-48. PMID 22810847 DOI: 10.1007/S00418-012-0989-1 |
0.357 |
|
| 2012 |
Subramanian N, Wetzel A, Dombert B, Yadav P, Havlicek S, Jablonka S, Nassar MA, Blum R, Sendtner M. Role of Na(v)1.9 in activity-dependent axon growth in motoneurons. Human Molecular Genetics. 21: 3655-67. PMID 22641814 DOI: 10.1093/Hmg/Dds195 |
0.359 |
|
| 2012 |
Zuern C, Krenacs L, Starke S, Heimrich J, Palmetshofer A, Holtmann B, Sendtner M, Fischer T, Galle J, Wanner C, Seibold S. Microtubule associated tumor suppressor 1 deficient mice develop spontaneous heart hypertrophy and SLE-like lymphoproliferative disease. International Journal of Oncology. 40: 1079-88. PMID 22200760 DOI: 10.3892/Ijo.2011.1311 |
0.33 |
|
| 2012 |
Horos R, Ijspeert H, Pospisilova D, Sendtner R, Andrieu-Soler C, Taskesen E, Nieradka A, Cmejla R, Sendtner M, Touw IP, von Lindern M. Ribosomal deficiencies in Diamond-Blackfan anemia impair translation of transcripts essential for differentiation of murine and human erythroblasts. Blood. 119: 262-72. PMID 22058113 DOI: 10.1182/Blood-2011-06-358200 |
0.325 |
|
| 2011 |
Ferraiuolo L, Kirby J, Grierson AJ, Sendtner M, Shaw PJ. Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis. Nature Reviews. Neurology. 7: 616-30. PMID 22051914 DOI: 10.1038/Nrneurol.2011.152 |
0.451 |
|
| 2011 |
Jablonka S, Holtmann B, Sendtner M, Metzger F. Therapeutic effects of PEGylated insulin-like growth factor I in the pmn mouse model of motoneuron disease. Experimental Neurology. 232: 261-9. PMID 21963648 DOI: 10.1016/J.Expneurol.2011.09.015 |
0.42 |
|
| 2011 |
Conrad R, Jablonka S, Sczepan T, Sendtner M, Wiese S, Klausmeyer A. Lectin-based isolation and culture of mouse embryonic motoneurons. Journal of Visualized Experiments : Jove. PMID 21946816 DOI: 10.3791/3200 |
0.374 |
|
| 2011 |
Sendtner M. Regenerative medicine: Bespoke cells for the human brain. Nature. 476: 158-9. PMID 21833079 DOI: 10.1038/476158A |
0.362 |
|
| 2011 |
Drepper C, Sendtner M. A new postal code for dendritic mRNA transport in neurons. Embo Reports. 12: 614-6. PMID 21681203 DOI: 10.1038/Embor.2011.119 |
0.338 |
|
| 2011 |
Blázquez C, Chiarlone A, Sagredo O, Aguado T, Pazos MR, Resel E, Palazuelos J, Julien B, Salazar M, Börner C, Benito C, Carrasco C, Diez-Zaera M, Paoletti P, Díaz-Hernández M, ... ... Sendtner M, et al. Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease. Brain : a Journal of Neurology. 134: 119-36. PMID 20929960 DOI: 10.1093/Brain/Awq278 |
0.32 |
|
| 2011 |
Drepper C, Herrmann T, Wessig C, Beck M, Sendtner M. C-terminal FUS/TLS mutations in familial and sporadic ALS in Germany. Neurobiology of Aging. 32: 548.e1-4. PMID 20018407 DOI: 10.1016/J.Neurobiolaging.2009.11.017 |
0.333 |
|
| 2010 |
Michaelsen K, Zagrebelsky M, Berndt-Huch J, Polack M, Buschler A, Sendtner M, Korte M. Neurotrophin receptors TrkB.T1 and p75NTR cooperate in modulating both functional and structural plasticity in mature hippocampal neurons. The European Journal of Neuroscience. 32: 1854-65. PMID 20955473 DOI: 10.1111/J.1460-9568.2010.07460.X |
0.343 |
|
| 2010 |
Linker RA, Lee DH, Demir S, Wiese S, Kruse N, Siglienti I, Gerhardt E, Neumann H, Sendtner M, Lühder F, Gold R. Functional role of brain-derived neurotrophic factor in neuroprotective autoimmunity: therapeutic implications in a model of multiple sclerosis. Brain : a Journal of Neurology. 133: 2248-63. PMID 20826430 DOI: 10.1093/Brain/Awq179 |
0.387 |
|
| 2010 |
Sendtner M. Therapy development in spinal muscular atrophy. Nature Neuroscience. 13: 795-9. PMID 20581815 DOI: 10.1038/Nn.2565 |
0.428 |
|
| 2010 |
Ning K, Drepper C, Valori CF, Ahsan M, Wyles M, Higginbottom A, Herrmann T, Shaw P, Azzouz M, Sendtner M. PTEN depletion rescues axonal growth defect and improves survival in SMN-deficient motor neurons. Human Molecular Genetics. 19: 3159-68. PMID 20525971 DOI: 10.1093/Hmg/Ddq226 |
0.506 |
|
| 2010 |
Brockington A, Heath PR, Holden H, Kasher P, Bender FL, Claes F, Lambrechts D, Sendtner M, Carmeliet P, Shaw PJ. Downregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGFdelta/delta mouse model of amyotrophic lateral sclerosis. Bmc Genomics. 11: 203. PMID 20346106 DOI: 10.1186/1471-2164-11-203 |
0.509 |
|
| 2010 |
Glinka M, Herrmann T, Funk N, Havlicek S, Rossoll W, Winkler C, Sendtner M. The heterogeneous nuclear ribonucleoprotein-R is necessary for axonal beta-actin mRNA translocation in spinal motor neurons. Human Molecular Genetics. 19: 1951-66. PMID 20167579 DOI: 10.1093/Hmg/Ddq073 |
0.73 |
|
| 2010 |
Rauskolb S, Zagrebelsky M, Dreznjak A, Deogracias R, Matsumoto T, Wiese S, Erne B, Sendtner M, Schaeren-Wiemers N, Korte M, Barde YA. Global deprivation of brain-derived neurotrophic factor in the CNS reveals an area-specific requirement for dendritic growth. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 1739-49. PMID 20130183 DOI: 10.1523/Jneurosci.5100-09.2010 |
0.44 |
|
| 2010 |
Michaud M, Arnoux T, Bielli S, Durand E, Rotrou Y, Jablonka S, Robert F, Giraudon-Paoli M, Riessland M, Mattei MG, Andriambeloson E, Wirth B, Sendtner M, Gallego J, Pruss RM, et al. Neuromuscular defects and breathing disorders in a new mouse model of spinal muscular atrophy. Neurobiology of Disease. 38: 125-35. PMID 20085811 DOI: 10.1016/J.Nbd.2010.01.006 |
0.434 |
|
| 2010 |
Wiese S, Herrmann T, Drepper C, Jablonka S, Funk N, Klausmeyer A, Rogers ML, Rush R, Sendtner M. Isolation and enrichment of embryonic mouse motoneurons from the lumbar spinal cord of individual mouse embryos. Nature Protocols. 5: 31-8. PMID 20057379 DOI: 10.1038/Nprot.2009.193 |
0.439 |
|
| 2010 |
Simon CM, Jablonka S, Ruiz R, Tabares L, Sendtner M. Ciliary neurotrophic factor-induced sprouting preserves motor function in a mouse model of mild spinal muscular atrophy. Human Molecular Genetics. 19: 973-86. PMID 20022887 DOI: 10.1093/Hmg/Ddp562 |
0.473 |
|
| 2009 |
Strelau J, Strzelczyk A, Rusu P, Bendner G, Wiese S, Diella F, Altick AL, von Bartheld CS, Klein R, Sendtner M, Unsicker K. Progressive postnatal motoneuron loss in mice lacking GDF-15. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 13640-8. PMID 19864576 DOI: 10.1523/Jneurosci.1133-09.2009 |
0.497 |
|
| 2009 |
Trimbuch T, Beed P, Vogt J, Schuchmann S, Maier N, Kintscher M, Breustedt J, Schuelke M, Streu N, Kieselmann O, Brunk I, Laube G, Strauss U, Battefeld A, Wende H, ... ... Sendtner M, et al. Synaptic PRG-1 modulates excitatory transmission via lipid phosphate-mediated signaling. Cell. 138: 1222-35. PMID 19766573 DOI: 10.1016/J.Cell.2009.06.050 |
0.348 |
|
| 2009 |
Rak K, Lechner BD, Schneider C, Drexl H, Sendtner M, Jablonka S. Valproic acid blocks excitability in SMA type I mouse motor neurons. Neurobiology of Disease. 36: 477-87. PMID 19733665 DOI: 10.1016/J.Nbd.2009.08.014 |
0.375 |
|
| 2009 |
Fischer M, Pereira PM, Holtmann B, Simon CM, Hanauer A, Heisenberg M, Sendtner M. P90 Ribosomal s6 kinase 2 negatively regulates axon growth in motoneurons. Molecular and Cellular Neurosciences. 42: 134-41. PMID 19555761 DOI: 10.1016/J.Mcn.2009.06.006 |
0.441 |
|
| 2009 |
Fischer M, Raabe T, Heisenberg M, Sendtner M. Drosophila RSK negatively regulates bouton number at the neuromuscular junction. Developmental Neurobiology. 69: 212-20. PMID 19160443 DOI: 10.1002/Dneu.20700 |
0.332 |
|
| 2009 |
Sendtner M. Stem cells: Tailor-made diseased neurons. Nature. 457: 269-70. PMID 19148087 DOI: 10.1038/457269A |
0.412 |
|
| 2008 |
Poesen K, Lambrechts D, Van Damme P, Dhondt J, Bender F, Frank N, Bogaert E, Claes B, Heylen L, Verheyen A, Raes K, Tjwa M, Eriksson U, Shibuya M, Nuydens R, ... ... Sendtner M, et al. Novel role for vascular endothelial growth factor (VEGF) receptor-1 and its ligand VEGF-B in motor neuron degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10451-9. PMID 18923022 DOI: 10.1523/Jneurosci.1092-08.2008 |
0.335 |
|
| 2008 |
Brors D, Hansen S, Mlynski R, Volkenstein S, Aletsee C, Sendtner M, Ryan AF, Dazert S. Spiral ganglion outgrowth and hearing development in p75-deficient mice. Audiology & Neuro-Otology. 13: 388-95. PMID 18663291 DOI: 10.1159/000148202 |
0.329 |
|
| 2008 |
Lang EM, Schlegel N, Reiners K, Hofmann GO, Sendtner M, Asan E. Single-dose application of CNTF and BDNF improves remyelination of regenerating nerve fibers after C7 ventral root avulsion and replantation. Journal of Neurotrauma. 25: 384-400. PMID 18373486 DOI: 10.1089/Neu.2007.0396 |
0.375 |
|
| 2008 |
Linker RA, Kruse N, Israel S, Wei T, Seubert S, Hombach A, Holtmann B, Luhder F, Ransohoff RM, Sendtner M, Gold R. Leukemia inhibitory factor deficiency modulates the immune response and limits autoimmune demyelination: a new role for neurotrophic cytokines in neuroinflammation. Journal of Immunology (Baltimore, Md. : 1950). 180: 2204-13. PMID 18250427 DOI: 10.4049/Jimmunol.180.4.2204 |
0.373 |
|
| 2007 |
Wiese S, Jablonka S, Holtmann B, Orel N, Rajagopal R, Chao MV, Sendtner M. Adenosine receptor A2A-R contributes to motoneuron survival by transactivating the tyrosine kinase receptor TrkB. Proceedings of the National Academy of Sciences of the United States of America. 104: 17210-5. PMID 17940030 DOI: 10.1073/Pnas.0705267104 |
0.326 |
|
| 2007 |
Jablonka S, Beck M, Lechner BD, Mayer C, Sendtner M. Defective Ca2+ channel clustering in axon terminals disturbs excitability in motoneurons in spinal muscular atrophy. The Journal of Cell Biology. 179: 139-49. PMID 17923533 DOI: 10.1083/Jcb.200703187 |
0.411 |
|
| 2007 |
Schreiner S, Cossais F, Fischer K, Scholz S, Bösl MR, Holtmann B, Sendtner M, Wegner M. Hypomorphic Sox10 alleles reveal novel protein functions and unravel developmental differences in glial lineages. Development (Cambridge, England). 134: 3271-81. PMID 17699610 DOI: 10.1242/Dev.003350 |
0.34 |
|
| 2007 |
Frebel K, Wiese S, Funk N, Pühringer D, Sendtner M. Differential modulation of neurite growth by the S- and the L-forms of bag1, a co-chaperone of Hsp70. Neuro-Degenerative Diseases. 4: 261-9. PMID 17596720 DOI: 10.1159/000101850 |
0.399 |
|
| 2007 |
Aguado T, Romero E, Monory K, Palazuelos J, Sendtner M, Marsicano G, Lutz B, Guzmán M, Galve-Roperh I. The CB1 cannabinoid receptor mediates excitotoxicity-induced neural progenitor proliferation and neurogenesis. The Journal of Biological Chemistry. 282: 23892-8. PMID 17556369 DOI: 10.1074/Jbc.M700678200 |
0.303 |
|
| 2007 |
Kasperaviciute D, Weale ME, Shianna KV, Banks GT, Simpson CL, Hansen VK, Turner MR, Shaw CE, Al-Chalabi A, Pall HS, Goodall EF, Morrison KE, Orrell RW, Beck M, Jablonka S, ... Sendtner M, et al. Large-scale pathways-based association study in amyotrophic lateral sclerosis. Brain : a Journal of Neurology. 130: 2292-301. PMID 17439985 DOI: 10.1093/Brain/Awm055 |
0.316 |
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| 2007 |
Blak AA, Naserke T, Saarimäki-Vire J, Peltopuro P, Giraldo-Velasquez M, Vogt Weisenhorn DM, Prakash N, Sendtner M, Partanen J, Wurst W. Fgfr2 and Fgfr3 are not required for patterning and maintenance of the midbrain and anterior hindbrain. Developmental Biology. 303: 231-43. PMID 17150206 DOI: 10.1016/J.Ydbio.2006.11.008 |
0.335 |
|
| 2007 |
Bender FL, Fischer M, Funk N, Orel N, Rethwilm A, Sendtner M. High-efficiency gene transfer into cultured embryonic motoneurons using recombinant lentiviruses. Histochemistry and Cell Biology. 127: 439-48. PMID 17102992 DOI: 10.1007/S00418-006-0247-5 |
0.346 |
|
| 2007 |
Monani UR, Sendtner M, Coovert DD, Parsons DW, Andreassi C, Le TT, Jablonka S, Schrank B, Rossol W, Prior TW, Morris GE, Burghes AHM. Erratum: The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn-/- mice and results in a mouse with spinal muscular atrophy (Human Molecular Genetics (2000) vol. 9 (333-339)) Human Molecular Genetics. 16. DOI: 10.1093/Hmg/Ddm236 |
0.451 |
|
| 2006 |
Ito Y, Wiese S, Funk N, Chittka A, Rossoll W, Bömmel H, Watabe K, Wegner M, Sendtner M. Sox10 regulates ciliary neurotrophic factor gene expression in Schwann cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 7871-6. PMID 16684879 DOI: 10.1073/Pnas.0602332103 |
0.707 |
|
| 2006 |
Oberle S, Schober A, Meyer V, Holtmann B, Henderson C, Sendtner M, Unsicker K. Loss of leukemia inhibitory factor receptor beta or cardiotrophin-1 causes similar deficits in preganglionic sympathetic neurons and adrenal medulla. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1823-32. PMID 16467531 DOI: 10.1523/Jneurosci.4127-05.2006 |
0.443 |
|
| 2006 |
Jablonka S, Karle K, Sandner B, Andreassi C, von Au K, Sendtner M. Distinct and overlapping alterations in motor and sensory neurons in a mouse model of spinal muscular atrophy. Human Molecular Genetics. 15: 511-8. PMID 16396995 DOI: 10.1093/Hmg/Ddi467 |
0.464 |
|
| 2006 |
Sendtner M. Damaging secretions: chromogranins team up with mutant SOD1. Nature Neuroscience. 9: 12-4. PMID 16378088 DOI: 10.1038/Nn0106-12 |
0.379 |
|
| 2006 |
Chevrel G, Hohlfeld R, Sendtner M. The role of neurotrophins in muscle under physiological and pathological conditions. Muscle & Nerve. 33: 462-76. PMID 16228973 DOI: 10.1002/Mus.20444 |
0.316 |
|
| 2005 |
Barnabé-Heider F, Wasylnka JA, Fernandes KJ, Porsche C, Sendtner M, Kaplan DR, Miller FD. Evidence that embryonic neurons regulate the onset of cortical gliogenesis via cardiotrophin-1. Neuron. 48: 253-65. PMID 16242406 DOI: 10.1016/J.Neuron.2005.08.037 |
0.349 |
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| 2005 |
Götz R, Wiese S, Takayama S, Camarero GC, Rossoll W, Schweizer U, Troppmair J, Jablonka S, Holtmann B, Reed JC, Rapp UR, Sendtner M. Bag1 is essential for differentiation and survival of hematopoietic and neuronal cells. Nature Neuroscience. 8: 1169-78. PMID 16116448 DOI: 10.1038/Nn1524 |
0.724 |
|
| 2005 |
Langenhan T, Sendtner M, Holtmann B, Carroll P, Asan E. Ciliary neurotrophic factor-immunoreactivity in olfactory sensory neurons. Neuroscience. 134: 1179-94. PMID 16039789 DOI: 10.1016/J.Neuroscience.2005.05.017 |
0.391 |
|
| 2005 |
Lang EM, Schlegel N, Sendtner M, Asan E. Effects of root replantation and neurotrophic factor treatment on long-term motoneuron survival and axonal regeneration after C7 spinal root avulsion. Experimental Neurology. 194: 341-54. PMID 16022862 DOI: 10.1016/J.Expneurol.2005.02.018 |
0.386 |
|
| 2005 |
Linker RA, Sendtner M, Gold R. Mechanisms of axonal degeneration in EAE--lessons from CNTF and MHC I knockout mice. Journal of the Neurological Sciences. 233: 167-72. PMID 15949503 DOI: 10.1016/J.Jns.2005.03.021 |
0.382 |
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| 2005 |
Lang EM, Asan E, Plesnila N, Hofmann GO, Sendtner M. Motoneuron survival after C7 nerve root avulsion and replantation in the adult rabbit: effects of local ciliary neurotrophic factor and brain-derived neurotrophic factor application. Plastic and Reconstructive Surgery. 115: 2042-50. PMID 15923853 DOI: 10.1097/01.Prs.0000163328.51271.Dd |
0.374 |
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| 2005 |
Holtmann B, Wiese S, Samsam M, Grohmann K, Pennica D, Martini R, Sendtner M. Triple knock-out of CNTF, LIF, and CT-1 defines cooperative and distinct roles of these neurotrophic factors for motoneuron maintenance and function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 1778-87. PMID 15716414 DOI: 10.1523/Jneurosci.4249-04.2005 |
0.416 |
|
| 2005 |
Banks GB, Kanjhan R, Wiese S, Kneussel M, Wong LM, O'Sullivan G, Sendtner M, Bellingham MC, Betz H, Noakes PG. Glycinergic and GABAergic synaptic activity differentially regulate motoneuron survival and skeletal muscle innervation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 1249-59. PMID 15689563 DOI: 10.1523/Jneurosci.1786-04.2005 |
0.377 |
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| 2005 |
Metzger F, Klapproth N, Kulik A, Sendtner M, Ballanyi K. Optical assessment of motoneuron function in a "twenty-four-hour" acute spinal cord slice model from fetal rats. Journal of Neuroscience Methods. 141: 309-20. PMID 15661313 DOI: 10.1016/J.Jneumeth.2004.07.016 |
0.334 |
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| 2004 |
Hartmann M, Brigadski T, Erdmann KS, Holtmann B, Sendtner M, Narz F, Lessmann V. Truncated TrkB receptor-induced outgrowth of dendritic filopodia involves the p75 neurotrophin receptor. Journal of Cell Science. 117: 5803-14. PMID 15507485 DOI: 10.1242/Jcs.01511 |
0.331 |
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| 2004 |
Wiese S, Beck M, Karch C, Sendtner M. Signalling mechanisms for survival of lesioned motoneurons. Acta Neurochirurgica. Supplement. 89: 21-35. PMID 15335098 DOI: 10.1007/978-3-7091-0603-7_4 |
0.425 |
|
| 2004 |
Grohmann K, Rossoll W, Kobsar I, Holtmann B, Jablonka S, Wessig C, Stoltenburg-Didinger G, Fischer U, Hübner C, Martini R, Sendtner M. Characterization of Ighmbp2 in motor neurons and implications for the pathomechanism in a mouse model of human spinal muscular atrophy with respiratory distress type 1 (SMARD1). Human Molecular Genetics. 13: 2031-42. PMID 15269181 DOI: 10.1093/Hmg/Ddh222 |
0.755 |
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| 2004 |
Fischer A, Schumacher N, Maier M, Sendtner M, Gessler M. The Notch target genes Hey1 and Hey2 are required for embryonic vascular development. Genes & Development. 18: 901-11. PMID 15107403 DOI: 10.1101/Gad.291004 |
0.316 |
|
| 2004 |
Jablonka S, Wiese S, Sendtner M. Axonal defects in mouse models of motoneuron disease. Journal of Neurobiology. 58: 272-86. PMID 14704958 DOI: 10.1002/Neu.10313 |
0.433 |
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| 2004 |
Sendtner M. Mouse mutants and cell culture models of motoneuron disease Drug Discovery Today: Disease Models. 1: 345-350. DOI: 10.1016/J.Ddmod.2004.10.008 |
0.323 |
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| 2003 |
Rossoll W, Jablonka S, Andreassi C, Kröning AK, Karle K, Monani UR, Sendtner M. Smn, the spinal muscular atrophy-determining gene product, modulates axon growth and localization of beta-actin mRNA in growth cones of motoneurons. The Journal of Cell Biology. 163: 801-12. PMID 14623865 DOI: 10.1083/Jcb.200304128 |
0.712 |
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| 2003 |
Jablonka S, Sendtner M. Molecular and cellular basis of spinal muscular atrophy. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group On Motor Neuron Diseases. 4: 144-9. PMID 13129800 DOI: 10.1080/14660820310011296 |
0.455 |
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| 2003 |
Naumann T, Schnell O, Zhi Q, Kirsch M, Schubert KO, Sendtner M, Hofmann HD. Endogenous ciliary neurotrophic factor protects GABAergic, but not cholinergic, septohippocampal neurons following fimbria-fornix transection. Brain Pathology (Zurich, Switzerland). 13: 309-21. PMID 12946020 DOI: 10.1111/J.1750-3639.2003.Tb00030.X |
0.423 |
|
| 2003 |
Asan E, Langenhan T, Holtmann B, Bock H, Sendtner M, Carroll P. Ciliary neurotrophic factor in the olfactory bulb of rats and mice. Neuroscience. 120: 99-112. PMID 12849744 DOI: 10.1016/S0306-4522(03)00211-2 |
0.411 |
|
| 2003 |
Gatzinsky KP, Holtmann B, Daraie B, Berthold CH, Sendtner M. Early onset of degenerative changes at nodes of Ranvier in alpha-motor axons of Cntf null (-/-) mutant mice. Glia. 42: 340-9. PMID 12730954 DOI: 10.1002/Glia.10221 |
0.427 |
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| 2003 |
Monani UR, Pastore MT, Gavrilina TO, Jablonka S, Le TT, Andreassi C, DiCocco JM, Lorson C, Androphy EJ, Sendtner M, Podell M, Burghes AH. A transgene carrying an A2G missense mutation in the SMN gene modulates phenotypic severity in mice with severe (type I) spinal muscular atrophy. The Journal of Cell Biology. 160: 41-52. PMID 12515823 DOI: 10.1083/Jcb.200208079 |
0.476 |
|
| 2002 |
Bommel H, Xie G, Rossoll W, Wiese S, Jablonka S, Boehm T, Sendtner M. Missense mutation in the tubulin-specific chaperone E (Tbce) gene in the mouse mutant progressive motor neuronopathy, a model of human motoneuron disease. The Journal of Cell Biology. 159: 563-9. PMID 12446740 DOI: 10.1083/Jcb.200208001 |
0.73 |
|
| 2002 |
Thoenen H, Sendtner M. Neurotrophins: from enthusiastic expectations through sobering experiences to rational therapeutic approaches. Nature Neuroscience. 5: 1046-50. PMID 12403983 DOI: 10.1038/Nn938 |
0.338 |
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| 2002 |
Jablonka S, Holtmann B, Meister G, Bandilla M, Rossoll W, Fischer U, Sendtner M. Gene targeting of Gemin2 in mice reveals a correlation between defects in the biogenesis of U snRNPs and motoneuron cell death. Proceedings of the National Academy of Sciences of the United States of America. 99: 10126-31. PMID 12091709 DOI: 10.1073/Pnas.152318699 |
0.736 |
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| 2002 |
Linker RA, Mäurer M, Gaupp S, Martini R, Holtmann B, Giess R, Rieckmann P, Lassmann H, Toyka KV, Sendtner M, Gold R. CNTF is a major protective factor in demyelinating CNS disease: a neurotrophic cytokine as modulator in neuroinflammation. Nature Medicine. 8: 620-4. PMID 12042814 DOI: 10.1038/Nm0602-620 |
0.405 |
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| 2002 |
Giess R, Holtmann B, Braga M, Grimm T, Müller-Myhsok B, Toyka KV, Sendtner M. Early onset of severe familial amyotrophic lateral sclerosis with a SOD-1 mutation: potential impact of CNTF as a candidate modifier gene. American Journal of Human Genetics. 70: 1277-86. PMID 11951178 DOI: 10.1086/340427 |
0.345 |
|
| 2002 |
Giess R, Mäurer M, Linker R, Gold R, Warmuth-Metz M, Toyka KV, Sendtner M, Rieckmann P. Association of a null mutation in the CNTF gene with early onset of multiple sclerosis. Archives of Neurology. 59: 407-9. PMID 11890844 DOI: 10.1001/Archneur.59.3.407 |
0.339 |
|
| 2002 |
Schweizer U, Gunnersen J, Karch C, Wiese S, Holtmann B, Takeda K, Akira S, Sendtner M. Conditional gene ablation of Stat3 reveals differential signaling requirements for survival of motoneurons during development and after nerve injury in the adult. The Journal of Cell Biology. 156: 287-97. PMID 11807093 DOI: 10.1083/Jcb.200107009 |
0.436 |
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| 2002 |
Rossoll W, Kröning AK, Ohndorf UM, Steegborn C, Jablonka S, Sendtner M. Specific interaction of Smn, the spinal muscular atrophy determining gene product, with hnRNP-R and gry-rbp/hnRNP-Q: a role for Smn in RNA processing in motor axons? Human Molecular Genetics. 11: 93-105. PMID 11773003 DOI: 10.1093/Hmg/11.1.93 |
0.741 |
|
| 2001 |
Sendtner M. Molecular mechanisms in spinal muscular atrophy: models and perspectives. Current Opinion in Neurology. 14: 629-34. PMID 11562575 DOI: 10.1097/00019052-200110000-00012 |
0.394 |
|
| 2001 |
Grohmann K, Schuelke M, Diers A, Hoffmann K, Lucke B, Adams C, Bertini E, Leonhardt-Horti H, Muntoni F, Ouvrier R, Pfeufer A, Rossi R, Van Maldergem L, Wilmshurst JM, Wienker TF, ... Sendtner M, et al. Mutations in the gene encoding immunoglobulin mu-binding protein 2 cause spinal muscular atrophy with respiratory distress type 1. Nature Genetics. 29: 75-7. PMID 11528396 DOI: 10.1038/Ng703 |
0.383 |
|
| 2001 |
Beck M, Karch C, Wiese S, Sendtner M. Motoneuron cell death and neurotrophic factors: basic models for development of new therapeutic strategies in ALS. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group On Motor Neuron Diseases. 2: S55-68. PMID 11465926 DOI: 10.1080/146608201300079454 |
0.452 |
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| 2001 |
Jablonka S, Bandilla M, Wiese S, Bühler D, Wirth B, Sendtner M, Fischer U. Co-regulation of survival of motor neuron (SMN) protein and its interactor SIP1 during development and in spinal muscular atrophy. Human Molecular Genetics. 10: 497-505. PMID 11181573 DOI: 10.1093/Hmg/10.5.497 |
0.485 |
|
| 2001 |
Wiese S, Pei G, Karch C, Troppmair J, Holtmann B, Rapp UR, Sendtner M. Specific function of B-Raf in mediating survival of embryonic motoneurons and sensory neurons. Nature Neuroscience. 4: 137-42. PMID 11175873 DOI: 10.1038/83960 |
0.414 |
|
| 2001 |
Oppenheim RW, Wiese S, Prevette D, Armanini M, Wang S, Houenou LJ, Holtmann B, Gotz R, Pennica D, Sendtner M. Cardiotrophin-1, a muscle-derived cytokine, is required for the survival of subpopulations of developing motoneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 1283-91. PMID 11160399 DOI: 10.1523/Jneurosci.21-04-01283.2001 |
0.396 |
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| 2000 |
Nishimune H, Vasseur S, Wiese S, Birling MC, Holtmann B, Sendtner M, Iovanna JL, Henderson CE. Reg-2 is a motoneuron neurotrophic factor and a signalling intermediate in the CNTF survival pathway. Nature Cell Biology. 2: 906-14. PMID 11146655 DOI: 10.1038/35046558 |
0.423 |
|
| 2000 |
Götz R, Karch C, Digby MR, Troppmair J, Rapp UR, Sendtner M. The neuronal apoptosis inhibitory protein suppresses neuronal differentiation and apoptosis in PC12 cells. Human Molecular Genetics. 9: 2479-89. PMID 11030753 DOI: 10.1093/Hmg/9.17.2479 |
0.442 |
|
| 2000 |
Coovert DD, Le TT, Morris GE, Man NT, Kralewski M, Sendtner M, Burghes AH. Does the survival motor neuron protein (SMN) interact with Bcl-2? Journal of Medical Genetics. 37: 536-9. PMID 10970187 DOI: 10.1136/Jmg.37.7.536 |
0.45 |
|
| 2000 |
Sendtner M, Pei G, Beck M, Schweizer U, Wiese S. Developmental motoneuron cell death and neurotrophic factors. Cell and Tissue Research. 301: 71-84. PMID 10928282 DOI: 10.1007/S004410000217 |
0.455 |
|
| 2000 |
Jablonka S, Rossoll W, Schrank B, Sendtner M. The role of SMN in spinal muscular atrophy. Journal of Neurology. 247: I37-42. PMID 10795885 DOI: 10.1007/S004150050555 |
0.708 |
|
| 2000 |
Giess R, Beck M, Goetz R, Nitsch RM, Toyka KV, Sendtner M. Potential role of LIF as a modifier gene in the pathogenesis of amyotrophic lateral sclerosis. Neurology. 54: 1003-5. PMID 10691006 DOI: 10.1212/Wnl.54.4.1003 |
0.354 |
|
| 2000 |
Jablonka S, Schrank B, Kralewski M, Rossoll W, Sendtner M. Reduced survival motor neuron (Smn) gene dose in mice leads to motor neuron degeneration: an animal model for spinal muscular atrophy type III. Human Molecular Genetics. 9: 341-6. PMID 10655542 DOI: 10.1093/Hmg/9.3.341 |
0.745 |
|
| 2000 |
Monani UR, Sendtner M, Coovert DD, Parsons DW, Andreassi C, Le TT, Jablonka S, Schrank B, Rossoll W, Rossol W, Prior TW, Morris GE, Burghes AH. The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn(-/-) mice and results in a mouse with spinal muscular atrophy. Human Molecular Genetics. 9: 333-9. PMID 10655541 DOI: 10.1093/Hmg/9.3.333 |
0.742 |
|
| 1999 |
Holtmann B, Zielasek J, Toyka KV, Sendtner M. Comparative analysis of motoneuron loss and functional deficits in PMN mice: implications for human motoneuron disease. Journal of the Neurological Sciences. 169: 140-7. PMID 10540023 DOI: 10.1016/S0022-510X(99)00237-3 |
0.41 |
|
| 1999 |
Wiese S, Digby MR, Gunnersen JM, Götz R, Pei G, Holtmann B, Lowenthal J, Sendtner M. The anti-apoptotic protein ITA is essential for NGF-mediated survival of embryonic chick neurons. Nature Neuroscience. 2: 978-83. PMID 10526336 DOI: 10.1038/14777 |
0.4 |
|
| 1999 |
Wiese S, Metzger F, Holtmann B, Sendtner M. Mechanical and excitotoxic lesion of motoneurons: effects of neurotrophins and ciliary neurotrophic factor on survival and regeneration. Acta Neurochirurgica. Supplement. 73: 31-9. PMID 10494338 DOI: 10.1007/978-3-7091-6391-7_5 |
0.421 |
|
| 1999 |
Lüder CG, Giraldo-Velásquez M, Sendtner M, Gross U. Toxoplasma gondii in primary rat CNS cells: differential contribution of neurons, astrocytes, and microglial cells for the intracerebral development and stage differentiation. Experimental Parasitology. 93: 23-32. PMID 10464035 DOI: 10.1006/Expr.1999.4421 |
0.341 |
|
| 1999 |
Nakashima K, Wiese S, Yanagisawa M, Arakawa H, Kimura N, Hisatsune T, Yoshida K, Kishimoto T, Sendtner M, Taga T. Developmental requirement of gp130 signaling in neuronal survival and astrocyte differentiation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 5429-34. PMID 10377352 DOI: 10.1523/Jneurosci.19-13-05429.1999 |
0.406 |
|
| 1999 |
Wiese S, Metzger F, Holtmann B, Sendtner M. The role of p75NTR in modulating neurotrophin survival effects in developing motoneurons. The European Journal of Neuroscience. 11: 1668-76. PMID 10215920 DOI: 10.1046/J.1460-9568.1999.00585.X |
0.425 |
|
| 1998 |
Cayouette M, Behn D, Sendtner M, Lachapelle P, Gravel C. Intraocular gene transfer of ciliary neurotrophic factor prevents death and increases responsiveness of rod photoreceptors in the retinal degeneration slow mouse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 9282-93. PMID 9801367 DOI: 10.1523/Jneurosci.18-22-09282.1998 |
0.327 |
|
| 1998 |
Sendtner M. Neurotrophic factors: effects in modulating properties of the neuromuscular endplate. Cytokine & Growth Factor Reviews. 9: 1-7. PMID 9720752 DOI: 10.1016/S1359-6101(97)00033-6 |
0.364 |
|
| 1998 |
Giess R, Goetz R, Schrank B, Ochs G, Sendtner M, Toyka K. Potential implications of a ciliary neurotrophic factor gene mutation in a German population of patients with motor neuron disease. Muscle & Nerve. 21: 236-8. PMID 9466600 DOI: 10.1002/(Sici)1097-4598(199802)21:2<236::Aid-Mus12>3.0.Co;2-# |
0.393 |
|
| 1998 |
Metzger F, Wiese S, Sendtner M. Effect of glutamate on dendritic growth in embryonic rat motoneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 1735-42. PMID 9464998 DOI: 10.1523/Jneurosci.18-05-01735.1998 |
0.374 |
|
| 1997 |
Sendtner M, Götz R, Holtmann B, Thoenen H. Endogenous ciliary neurotrophic factor is a lesion factor for axotomized motoneurons in adult mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 6999-7006. PMID 9278535 DOI: 10.1523/Jneurosci.17-18-06999.1997 |
0.395 |
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| 1997 |
Schrank B, Götz R, Gunnersen JM, Ure JM, Toyka KV, Smith AG, Sendtner M. Inactivation of the survival motor neuron gene, a candidate gene for human spinal muscular atrophy, leads to massive cell death in early mouse embryos. Proceedings of the National Academy of Sciences of the United States of America. 94: 9920-5. PMID 9275227 DOI: 10.1073/Pnas.94.18.9920 |
0.483 |
|
| 1997 |
Gravel C, Götz R, Lorrain A, Sendtner M. Adenoviral gene transfer of ciliary neurotrophic factor and brain-derived neurotrophic factor leads to long-term survival of axotomized motor neurons. Nature Medicine. 3: 765-70. PMID 9212104 DOI: 10.1038/Nm0797-765 |
0.471 |
|
| 1997 |
Sendtner M. Gene therapy for motor neuron disease. Nature Medicine. 3: 380-1. PMID 9095166 DOI: 10.1038/Nm0497-380 |
0.431 |
|
| 1996 |
Barres BA, Burne JF, Holtmann B, Thoenen H, Sendtner M, Raff MC. Ciliary Neurotrophic Factor Enhances the Rate of Oligodendrocyte Generation Molecular and Cellular Neurosciences. 8: 146-56. PMID 8954629 DOI: 10.1006/Mcne.1996.0053 |
0.378 |
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| 1996 |
Sendtner M, Holtmann B, Hughes RA. The response of motoneurons to neurotrophins. Neurochemical Research. 21: 831-41. PMID 8873088 DOI: 10.1007/Bf02532307 |
0.403 |
|
| 1996 |
Dittrich F, Ochs G, Grosse-Wilde A, Berweiler U, Yan Q, Miller JA, Toyka KV, Sendtner M. Pharmacokinetics of intrathecally applied BDNF and effects on spinal motoneurons. Experimental Neurology. 141: 225-39. PMID 8812156 DOI: 10.1006/Exnr.1996.0157 |
0.35 |
|
| 1996 |
Sendtner M, Götz R, Holtmann B, Escary JL, Masu Y, Carroll P, Wolf E, Brem G, Brület P, Thoenen H. Cryptic physiological trophic support of motoneurons by LIF revealed by double gene targeting of CNTF and LIF. Current Biology : Cb. 6: 686-94. PMID 8793295 DOI: 10.1016/S0960-9822(09)00450-3 |
0.401 |
|
| 1996 |
Michaelidis TM, Sendtner M, Cooper JD, Airaksinen MS, Holtmann B, Meyer M, Thoenen H. Inactivation of bcl-2 results in progressive degeneration of motoneurons, sympathetic and sensory neurons during early postnatal development. Neuron. 17: 75-89. PMID 8755480 DOI: 10.1016/S0896-6273(00)80282-2 |
0.449 |
|
| 1996 |
Maysinger D, Krieglstein K, Filipovic-Grcic J, Sendtner M, Unsicker K, Richardson P. Microencapsulated ciliary neurotrophic factor: physical properties and biological activities. Experimental Neurology. 138: 177-88. PMID 8620916 DOI: 10.1006/Exnr.1996.0056 |
0.311 |
|
| 1996 |
Müller WEG, Romero FJ, Pergande G, Perovic S, Graeber MB, Kösel S, Egensperger R, Schnopp NM, Mehraein P, Miura M, Okada M, Von Holst A, Lefcort FB, Rodriguez-Tébar A, Michaille JJ, ... ... Sendtner M, et al. The 3rd German-Japanese Joint Workshop. Cell Death in the CNS: Molecules and Programs Journal of Brain Research. 37: 575-600. |
0.402 |
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| 1995 |
Sendtner M. Molecular biology of neurotrophic factors. Bailliã¨Re's Clinical Neurology. 4: 575-91. PMID 8599725 |
0.372 |
|
| 1995 |
Li M, Sendtner M, Smith A. Essential function of LIF receptor in motor neurons. Nature. 378: 724-7. PMID 7501019 DOI: 10.1038/378724A0 |
0.471 |
|
| 1994 |
Sendtner M, Carroll P, Holtmann B, Hughes RA, Thoenen H. Ciliary neurotrophic factor. Journal of Neurobiology. 25: 1436-53. PMID 7852996 DOI: 10.1002/neu.480251110 |
0.331 |
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| 1994 |
Sendtner M, Dittrich F, Hughes RA, Thoenen H. Actions of CNTF and neurotrophins on degenerating motoneurons: preclinical studies and clinical implications. Journal of the Neurological Sciences. 124: 77-83. PMID 7807152 DOI: 10.1016/0022-510X(94)90187-2 |
0.458 |
|
| 1993 |
Barres BA, Jacobson MD, Schmid R, Sendtner M, Raff MC. Does oligodendrocyte survival depend on axons? Current Biology : Cb. 3: 489-97. PMID 15335686 DOI: 10.1016/0960-9822(93)90039-Q |
0.387 |
|
| 1993 |
Hughes RA, Sendtner M, Goldfarb M, Lindholm D, Thoenen H. Evidence that fibroblast growth factor 5 is a major muscle-derived survival factor for cultured spinal motoneurons. Neuron. 10: 369-77. PMID 8461132 DOI: 10.1016/0896-6273(93)90327-N |
0.344 |
|
| 1993 |
Masu Y, Wolf E, Holtmann B, Sendtner M, Brem G, Thoenen H. Disruption of the CNTF gene results in motor neuron degeneration. Nature. 365: 27-32. PMID 8361533 DOI: 10.1038/365027A0 |
0.474 |
|
| 1993 |
Carroll P, Sendtner M, Meyer M, Thoenen H. Rat ciliary neurotrophic factor (CNTF): gene structure and regulation of mRNA levels in glial cell cultures. Glia. 9: 176-87. PMID 8294148 DOI: 10.1002/Glia.440090303 |
0.309 |
|
| 1993 |
Hughes RA, Sendtner M, Thoenen H. Members of several gene families influence survival of rat motoneurons in vitro and in vivo. Journal of Neuroscience Research. 36: 663-71. PMID 8145295 DOI: 10.1002/Jnr.490360607 |
0.415 |
|
| 1993 |
Carroll P, Sendtner M, Meyer M, Thoenen H. Rat ciliary neurotrophic factor (CNTF) Glia. DOI: 10.1002/Glia.440090301 |
0.306 |
|
| 1992 |
Sendtner M, Schmalbruch H, Stöckli KA, Carroll P, Kreutzberg GW, Thoenen H. Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy. Nature. 358: 502-4. PMID 1641039 DOI: 10.1038/358502A0 |
0.625 |
|
| 1992 |
Sendtner M, Stöckli KA, Thoenen H. Synthesis and localization of ciliary neurotrophic factor in the sciatic nerve of the adult rat after lesion and during regeneration. The Journal of Cell Biology. 118: 139-48. PMID 1618901 DOI: 10.1083/Jcb.118.1.139 |
0.375 |
|
| 1992 |
Sendtner M, Holtmann B, Kolbeck R, Thoenen H, Barde YA. Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section. Nature. 360: 757-9. PMID 1465147 DOI: 10.1038/360757A0 |
0.415 |
|
| 1992 |
Sendtner M, Kreutzberg GW, Jennekens FG. Workshop on Trophic Factors in the Peripheral Nervous System. Capri, October 1991. Neuromuscular Disorders : Nmd. 2: 11-7. PMID 1356044 DOI: 10.1016/0960-8966(92)90021-W |
0.519 |
|
| 1991 |
Kaupmann K, Sendtner M, Stöckli KA, Jockusch H. The Gene for Ciliary Neurotrophic Factor (CNTF) Maps to Murine Chromosome 19 and its Expression is Not Affected in the Hereditary Motoneuron Disease 'Wobbler' of the Mouse. The European Journal of Neuroscience. 3: 1182-1186. PMID 12106247 DOI: 10.1111/J.1460-9568.1991.Tb00052.X |
0.345 |
|
| 1991 |
Stöckli KA, Lillien LE, Näher-Noé M, Breitfeld G, Hughes RA, Raff MC, Thoenen H, Sendtner M. Regional distribution, developmental changes, and cellular localization of CNTF-mRNA and protein in the rat brain. The Journal of Cell Biology. 115: 447-59. PMID 1918150 DOI: 10.1083/Jcb.115.2.447 |
0.378 |
|
| 1991 |
Sendtner M, Arakawa Y, Stöckli KA, Kreutzberg GW, Thoenen H. Effect of ciliary neurotrophic factor (CNTF) on motoneuron survival. Journal of Cell Science. Supplement. 15: 103-9. PMID 1824101 DOI: 10.1242/Jcs.1991.Supplement_15.14 |
0.594 |
|
| 1990 |
Sendtner M, Kreutzberg GW, Thoenen H. Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy. Nature. 345: 440-1. PMID 2342575 DOI: 10.1038/345440A0 |
0.633 |
|
| 1990 |
Arakawa Y, Sendtner M, Thoenen H. Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: comparison with other neurotrophic factors and cytokines. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 3507-15. PMID 2230940 DOI: 10.1523/Jneurosci.10-11-03507.1990 |
0.437 |
|
| 1989 |
Borasio GD, John J, Wittinghofer A, Barde YA, Sendtner M, Heumann R. ras p21 protein promotes survival and fiber outgrowth of cultured embryonic neurons. Neuron. 2: 1087-96. PMID 2696501 DOI: 10.1016/0896-6273(89)90233-X |
0.366 |
|
| 1989 |
Stöckli KA, Lottspeich F, Sendtner M, Masiakowski P, Carroll P, Götz R, Lindholm D, Thoenen H. Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor. Nature. 342: 920-3. PMID 2594085 DOI: 10.1038/342920A0 |
0.405 |
|
| 1989 |
Ernsberger U, Sendtner M, Rohrer H. Proliferation and differentiation of embryonic chick sympathetic neurons: effects of ciliary neurotrophic factor. Neuron. 2: 1275-84. PMID 2576210 DOI: 10.1016/0896-6273(89)90312-7 |
0.378 |
|
| 1989 |
Saadat S, Sendtner M, Rohrer H. Ciliary neurotrophic factor induces cholinergic differentiation of rat sympathetic neurons in culture. The Journal of Cell Biology. 108: 1807-16. PMID 2565906 DOI: 10.1083/Jcb.108.5.1807 |
0.334 |
|
| 1988 |
Hughes SM, Lillien LE, Raff MC, Rohrer H, Sendtner M. Ciliary neurotrophic factor induces type-2 astrocyte differentiation in culture. Nature. 335: 70-3. PMID 3412463 DOI: 10.1038/335070A0 |
0.383 |
|
| 1988 |
Sendtner M, Gnahn H, Wakade A, Thoenen H. Is activation of the Na+K+ pump necessary for NGF-mediated neuronal survival? The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 458-62. PMID 2828563 DOI: 10.1523/Jneurosci.08-02-00458.1988 |
0.344 |
|
| 1986 |
Dohrmann U, Edgar D, Sendtner M, Thoenen H. Muscle-derived factors that support survival and promote fiber outgrowth from embryonic chick spinal motor neurons in culture. Developmental Biology. 118: 209-21. PMID 3770299 DOI: 10.1016/0012-1606(86)90089-8 |
0.451 |
|
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