Wenjun Guo, Ph.D. - Publications

Affiliations: 
Albert Einstein College of Medicine, New York, New York, United States 

40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Cui J, Christin JR, Reisz JA, Cendali FI, Sanawar R, Coutinho De Miranda M, D'Alessandro A, Guo W. Targeting ABCA12-controlled ceramide homeostasis inhibits breast cancer stem cell function and chemoresistance. Science Advances. 9: eadh1891. PMID 38039374 DOI: 10.1126/sciadv.adh1891  0.731
2023 Liu Y, John P, Nishitani K, Cui J, Nishimura CD, Christin JR, Couturier N, Ren X, Wei Y, Pulanco MC, Galbo PM, Zhang X, Fu W, Cui W, Bartholdy BA, ... ... Guo W, et al. A SOX9-B7x axis safeguards dedifferentiated tumor cells from immune surveillance to drive breast cancer progression. Developmental Cell. PMID 37963469 DOI: 10.1016/j.devcel.2023.10.010  0.722
2023 Cui J, Zhang C, Lee JE, Bartholdy BA, Yang D, Liu Y, Erler P, Galbo PM, Hodge DQ, Huangfu D, Zheng D, Ge K, Guo W. MLL3 loss drives metastasis by promoting a hybrid epithelial-mesenchymal transition state. Nature Cell Biology. PMID 36604594 DOI: 10.1038/s41556-022-01045-0  0.713
2021 Sharma VP, Tang B, Wang Y, Duran CL, Karagiannis GS, Xue EA, Entenberg D, Borriello L, Coste A, Eddy RJ, Kim G, Ye X, Jones JG, Grunblatt E, Agi N, ... ... Guo W, et al. Live tumor imaging shows macrophage induction and TMEM-mediated enrichment of cancer stem cells during metastatic dissemination. Nature Communications. 12: 7300. PMID 34911937 DOI: 10.1038/s41467-021-27308-2  0.565
2021 Cui J, Guo W. Establishment and long-term culture of mouse mammary stem cell organoids and breast tumor organoids. Star Protocols. 2: 100577. PMID 34124696 DOI: 10.1016/j.xpro.2021.100577  0.714
2021 Liu Y, Guo W. SOX factors as cell-state regulators in the mammary gland and breast cancer. Seminars in Cell & Developmental Biology. PMID 33583737 DOI: 10.1016/j.semcdb.2021.01.002  0.565
2020 Christin JR, Wang C, Chung CY, Liu Y, Dravis C, Tang W, Oktay MH, Wahl GM, Guo W. Stem Cell Determinant SOX9 Promotes Lineage Plasticity and Progression in Basal-like Breast Cancer. Cell Reports. 31: 107742. PMID 32521267 DOI: 10.1016/J.Celrep.2020.107742  0.633
2020 Wei Q, Nakahara F, Asada N, Zhang D, Gao X, Xu C, Alfieri A, Brodin NP, Zimmerman SE, Mar JC, Guha C, Guo W, Frenette PS. Snai2 Maintains Bone Marrow Niche Cells by Repressing Osteopontin Expression. Developmental Cell. PMID 32413329 DOI: 10.1016/J.Devcel.2020.04.012  0.484
2018 Mao SPH, Park M, Cabrera RM, Christin JR, Karagiannis GS, Oktay MH, Zaiss DMW, Abrams SI, Guo W, Condeelis JS, Kenny PA, Segall JE. Loss of amphiregulin reduces myoepithelial cell coverage of mammary ducts and alters breast tumor growth. Breast Cancer Research : Bcr. 20: 131. PMID 30367629 DOI: 10.1186/S13058-018-1057-0  0.471
2018 Hodge DQ, Cui J, Gamble MJ, Guo W. Histone Variant MacroH2A1 Plays an Isoform-Specific Role in Suppressing Epithelial-Mesenchymal Transition. Scientific Reports. 8: 841. PMID 29339820 DOI: 10.1038/S41598-018-19364-4  0.719
2018 Zhang Z, Christin JR, Wang C, Ge K, Oktay M, Guo W. Abstract B47: Validation of novel breast cancer drivers using mammary stem cell-based somatic mouse models Molecular Cancer Research. 16. DOI: 10.1158/1557-3125.Advbc17-B47  0.571
2018 Mao S, Park M, Cabrera R, Christin J, Karagiannis G, Guo W, Condeelis J, Segall J. Abstract 5114: The role of amphiregulin in mammary gland development and breast cancer Cancer Research. 78: 5114-5114. DOI: 10.1158/1538-7445.Am2018-5114  0.529
2017 Li C, Hong L, Liu C, Min J, Hu M, Guo W. Astragalus polysaccharides increase the sensitivity of SKOV3 cells to cisplatin. Archives of Gynecology and Obstetrics. PMID 29103194 DOI: 10.1007/s00404-017-4580-9  0.302
2017 Donnelly SK, Cabrera R, Mao SPH, Christin JR, Wu B, Guo W, Bravo-Cordero JJ, Condeelis JS, Segall JE, Hodgson L. Rac3 regulates breast cancer invasion and metastasis by controlling adhesion and matrix degradation. The Journal of Cell Biology. PMID 29061650 DOI: 10.1083/Jcb.201704048  0.464
2017 Wang C, Christin JR, Oktay MH, Guo W. Lineage-Biased Stem Cells Maintain Estrogen-Receptor-Positive and -Negative Mouse Mammary Luminal Lineages. Cell Reports. 18: 2825-2835. PMID 28329676 DOI: 10.1016/J.Celrep.2017.02.071  0.585
2016 Zhang Z, Christin JR, Wang C, Ge K, Oktay MH, Guo W. Mammary-Stem-Cell-Based Somatic Mouse Models Reveal Breast Cancer Drivers Causing Cell Fate Dysregulation. Cell Reports. 16: 3146-56. PMID 27653681 DOI: 10.1016/J.Celrep.2016.08.048  0.577
2015 Pomp V, Leo C, Mauracher A, Korol D, Guo W, Varga Z. Differential expression of epithelial-mesenchymal transition and stem cell markers in intrinsic subtypes of breast cancer. Breast Cancer Research and Treatment. PMID 26467042 DOI: 10.1007/S10549-015-3598-6  0.537
2014 Condiotti R, Guo W, Ben-Porath I. Evolving views of breast cancer stem cells and their differentiation States. Critical Reviews in Oncogenesis. 19: 337-48. PMID 25404149  0.498
2014 Guo W. Concise review: breast cancer stem cells: regulatory networks, stem cell niches, and disease relevance. Stem Cells Translational Medicine. 3: 942-8. PMID 24904174 DOI: 10.5966/Sctm.2014-0020  0.659
2014 Luo ML, Gong C, Chen CH, Lee DY, Hu H, Huang P, Yao Y, Guo W, Reinhardt F, Wulf G, Lieberman J, Zhou XZ, Song E, Lu KP. Prolyl isomerase Pin1 acts downstream of miR200c to promote cancer stem-like cell traits in breast cancer. Cancer Research. 74: 3603-16. PMID 24786790 DOI: 10.1158/0008-5472.Can-13-2785  0.646
2013 Riemenschnitter C, Teleki I, Tischler V, Guo W, Varga Z. Stability and prognostic value of Slug, Sox9 and Sox10 expression in breast cancers treated with neoadjuvant chemotherapy. Springerplus. 2: 695. PMID 24404438 DOI: 10.1186/2193-1801-2-695  0.494
2013 Tam WL, Lu H, Buikhuisen J, Soh BS, Lim E, Reinhardt F, Wu ZJ, Krall JA, Bierie B, Guo W, Chen X, Liu XS, Brown M, Lim B, Weinberg RA. Protein kinase C α is a central signaling node and therapeutic target for breast cancer stem cells. Cancer Cell. 24: 347-64. PMID 24029232 DOI: 10.1016/J.Ccr.2013.08.005  0.679
2013 Guo W, Frenette PS. Alternative CD44 splicing in intestinal stem cells and tumorigenesis. Oncogene. 33: 537-8. PMID 23831568 DOI: 10.1038/Onc.2013.260  0.504
2012 Guo W, Keckesova Z, Donaher JL, Shibue T, Tischler V, Reinhardt F, Itzkovitz S, Noske A, Zürrer-Härdi U, Bell G, Tam WL, Mani SA, van Oudenaarden A, Weinberg RA. Slug and Sox9 cooperatively determine the mammary stem cell state. Cell. 148: 1015-28. PMID 22385965 DOI: 10.1016/J.Cell.2012.02.008  0.76
2011 Scheel C, Eaton EN, Li SH, Chaffer CL, Reinhardt F, Kah KJ, Bell G, Guo W, Rubin J, Richardson AL, Weinberg RA. Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast. Cell. 145: 926-40. PMID 21663795 DOI: 10.1016/J.Cell.2011.04.029  0.638
2011 May CD, Sphyris N, Evans KW, Werden SJ, Guo W, Mani SA. Epithelial-mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progression. Breast Cancer Research : Bcr. 13: 202. PMID 21392411 DOI: 10.1186/Bcr2789  0.742
2011 Scheel C, NgEaton E, Li SH, Chaffer CL, Reinhardt F, Kah K, Bell G, Guo W, Rubin J, Richardson A, Weinberg RA. Abstract LB-108: Formation and maintenance of mesenchymal and stem-cell states in the breast by paracrine and autocrine signals Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-108  0.671
2008 Huangfu D, Osafune K, Maehr R, Guo W, Eijkelenboom A, Chen S, Muhlestein W, Melton DA. Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2. Nature Biotechnology. 26: 1269-75. PMID 18849973 DOI: 10.1038/Nbt.1502  0.536
2008 Huangfu D, Maehr R, Guo W, Eijkelenboom A, Snitow M, Chen AE, Melton DA. Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds. Nature Biotechnology. 26: 795-7. PMID 18568017 DOI: 10.1038/Nbt1418  0.444
2008 Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY, Brooks M, Reinhard F, Zhang CC, Shipitsin M, Campbell LL, Polyak K, Brisken C, Yang J, Weinberg RA. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell. 133: 704-15. PMID 18485877 DOI: 10.1016/J.Cell.2008.03.027  0.75
2007 Liao MJ, Zhang CC, Zhou B, Zimonjic DB, Mani SA, Kaba M, Gifford A, Reinhardt F, Popescu NC, Guo W, Eaton EN, Lodish HF, Weinberg RA. Enrichment of a population of mammary gland cells that form mammospheres and have in vivo repopulating activity. Cancer Research. 67: 8131-8. PMID 17804725 DOI: 10.1158/0008-5472.Can-06-4493  0.72
2007 Pylayeva Y, Guo W, Giancotti FG. Analysis of integrin signaling in genetically engineered mouse models of mammary tumor progression. Methods in Enzymology. 426: 439-61. PMID 17697895 DOI: 10.1016/S0076-6879(07)26019-7  0.483
2006 Guo W, Pylayeva Y, Pepe A, Yoshioka T, Muller WJ, Inghirami G, Giancotti FG. Beta 4 integrin amplifies ErbB2 signaling to promote mammary tumorigenesis. Cell. 126: 489-502. PMID 16901783 DOI: 10.1016/J.Cell.2006.05.047  0.452
2005 Nikolopoulos SN, Blaikie P, Yoshioka T, Guo W, Puri C, Tacchetti C, Giancotti FG. Targeted deletion of the integrin beta4 signaling domain suppresses laminin-5-dependent nuclear entry of mitogen-activated protein kinases and NF-kappaB, causing defects in epidermal growth and migration. Molecular and Cellular Biology. 25: 6090-102. PMID 15988021 DOI: 10.1128/Mcb.25.14.6090-6102.2005  0.348
2005 Vidal A, Zacharoulis S, Guo W, Shaffer D, Giancotti F, Bramley AH, de la Hoz C, Jensen KK, Kato D, MacDonald DD, Knowles J, Yeh N, Frohman LA, Rafii S, Lyden D, et al. p130Rb2 and p27kip1 cooperate to control mobilization of angiogenic progenitors from the bone marrow. Proceedings of the National Academy of Sciences of the United States of America. 102: 6890-5. PMID 15867156 DOI: 10.1073/Pnas.0405823102  0.408
2005 Gubbay O, Guo W, Rae MT, Niven D, Howie AF, McNeilly AS, Xu L, Hillier SG. Anti-inflammatory and proliferative responses in human and ovine ovarian surface epithelial cells. Reproduction (Cambridge, England). 128: 607-14. PMID 15509706 DOI: 10.1530/rep.1.00272  0.355
2004 Nikolopoulos SN, Blaikie P, Yoshioka T, Guo W, Giancotti FG. Integrin beta4 signaling promotes tumor angiogenesis. Cancer Cell. 6: 471-83. PMID 15542431 DOI: 10.1016/J.Ccr.2004.09.029  0.417
2004 Guo W, Giancotti FG. Integrin signalling during tumour progression. Nature Reviews. Molecular Cell Biology. 5: 816-26. PMID 15459662 DOI: 10.1038/Nrm1490  0.466
2001 Mettouchi A, Klein S, Guo W, Lopez-Lago M, Lemichez E, Westwick JK, Giancotti FG. Integrin-specific activation of Rac controls progression through the G(1) phase of the cell cycle. Molecular Cell. 8: 115-27. PMID 11511365 DOI: 10.1016/S1097-2765(01)00285-4  0.377
1998 Fearnhead HO, Rodriguez J, Govek EE, Guo W, Kobayashi R, Hannon G, Lazebnik YA. Oncogene-dependent apoptosis is mediated by caspase-9 Proceedings of the National Academy of Sciences of the United States of America. 95: 13664-13669. PMID 9811857 DOI: 10.1073/Pnas.95.23.13664  0.309
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