Year |
Citation |
Score |
2014 |
Sharma A, Fonseca LL, Rajani C, Yanagida JK, Endo Y, Cline JM, Stone JC, Ji J, Ramos JW, Lorenzo PS. Targeted deletion of RasGRP1 impairs skin tumorigenesis. Carcinogenesis. 35: 1084-91. PMID 24464785 DOI: 10.1093/Carcin/Bgu016 |
0.727 |
|
2012 |
Fonseca LL, Lorenzo PS. Abstract 2144: RasGRP1 induces autophagy in primary human epidermal keratinocytes resembling fail-safe mechanisms triggered by oncogenic Ras Cancer Research. 72: 2144-2144. DOI: 10.1158/1538-7445.Am2012-2144 |
0.642 |
|
2010 |
Sharma A, Luke CT, Dower NA, Stone JC, Lorenzo PS. RasGRP1 is essential for Ras activation by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate in epidermal keratinocytes Journal of Biological Chemistry. 285: 15724-15730. PMID 20308057 DOI: 10.1074/Jbc.M109.100016 |
0.727 |
|
2010 |
Sharma A, Luke CT, Dower NA, Stone JC, Lorenzo PS. Abstract 315: RasGRP1 is a critical link to Ras activation by phorbol esters in mouse epidermal keratinocytes Cancer Research. 70: 315-315. DOI: 10.1158/1538-7445.Am10-315 |
0.717 |
|
2009 |
Diez FR, Garrido AA, Sharma A, Luke CT, Stone JC, Dower NA, Cline JM, Lorenzo PS. RasGRP1 transgenic mice develop cutaneous squamous cell carcinomas in response to skin wounding: potential role of granulocyte colony-stimulating factor. The American Journal of Pathology. 175: 392-9. PMID 19497993 DOI: 10.2353/Ajpath.2009.090036 |
0.707 |
|
2007 |
Luke CT, Oki-Idouchi CE, Cline JM, Lorenzo PS. RasGRP1 overexpression in the epidermis of transgenic mice contributes to tumor progression during multistage skin carcinogenesis Cancer Research. 67: 10190-10197. PMID 17974959 DOI: 10.1158/0008-5472.Can-07-2375 |
0.61 |
|
2007 |
Oki-Idouchi CE, Lorenzo PS. Transgenic overexpression of RasGRP1 in mouse epidermis results in spontaneous tumors of the skin. Cancer Research. 67: 276-80. PMID 17210708 DOI: 10.1158/0008-5472.Can-06-3080 |
0.633 |
|
2006 |
Okamura SM, Oki-Idouchi CE, Lorenzo PS. The exchange factor and diacylglycerol receptor RasGRP3 interacts with dynein light chain 1 through its C-terminal domain. The Journal of Biological Chemistry. 281: 36132-9. PMID 17012239 DOI: 10.1074/Jbc.M605093200 |
0.355 |
|
2006 |
Tuthill MC, Oki CE, Lorenzo PS. Differential effects of bryostatin 1 and 12-O-tetradecanoylphorbol-13-acetate on the regulation and activation of RasGRP1 in mouse epidermal keratinocytes. Molecular Cancer Therapeutics. 5: 602-10. PMID 16546974 DOI: 10.1158/1535-7163.Mct-05-0317 |
0.511 |
|
2003 |
Rambaratsingh RA, Stone JC, Blumberg PM, Lorenzo PS. RasGRP1 Represents a Novel Non-protein Kinase C Phorbol Ester Signaling Pathway in Mouse Epidermal Keratinocytes Journal of Biological Chemistry. 278: 52792-52801. PMID 14532295 DOI: 10.1074/jbc.M308240200 |
0.612 |
|
2002 |
Rong SB, Enyedy IJ, Qiao L, Zhao L, Ma D, Pearce LL, Lorenzo PS, Stone JC, Blumberg PM, Wang S, Kozikowski AP. Structural basis of RasGRP binding to high-affinity PKC ligands. Journal of Medicinal Chemistry. 45: 853-60. PMID 11831896 DOI: 10.1021/Jm010422Z |
0.339 |
|
2001 |
Shao L, Lewin NE, Lorenzo PS, Hu Z, Enyedy IJ, Garfield SH, Stone JC, Marner FJ, Blumberg PM, Wang S. Iridals are a novel class of ligands for phorbol ester receptors with modest selectivity for the RasGRP receptor subfamily. Journal of Medicinal Chemistry. 44: 3872-80. PMID 11689073 DOI: 10.1021/Jm010258F |
0.405 |
|
2000 |
Kronfeld I, Kazimirsky G, Lorenzo PS, Garfield SH, Blumberg PM, Brodie C. Phosphorylation of protein kinase Cdelta on distinct tyrosine residues regulates specific cellular functions. The Journal of Biological Chemistry. 275: 35491-8. PMID 10945993 DOI: 10.1074/Jbc.M005991200 |
0.331 |
|
2000 |
Li L, Lorenzo PS, Bogi K, Blumberg PM, Yuspa SH. Protein kinase Cdelta targets mitochondria, alters mitochondrial membrane potential, and induces apoptosis in normal and neoplastic keratinocytes when overexpressed by an adenoviral vector. Molecular and Cellular Biology. 19: 8547-58. PMID 10567579 DOI: 10.1128/Mcb.19.12.8547 |
0.33 |
|
1999 |
Bögi K, Lorenzo PS, Acs P, Szállási Z, Wagner GS, Blumberg PM. Comparison of the roles of the C1a and C1b domains of protein kinase C alpha in ligand induced translocation in NIH 3T3 cells. Febs Letters. 456: 27-30. PMID 10452523 DOI: 10.1016/S0014-5793(99)00927-8 |
0.31 |
|
1998 |
Brodie C, Bogi K, Acs P, Lorenzo PS, Baskin L, Blumberg PM. Protein kinase C delta (PKCdelta) inhibits the expression of glutamine synthetase in glial cells via the PKCdelta regulatory domain and its tyrosine phosphorylation. The Journal of Biological Chemistry. 273: 30713-8. PMID 9804846 DOI: 10.1074/Jbc.273.46.30713 |
0.33 |
|
1997 |
Acs P, Wang QJ, Bögi K, Marquez AM, Lorenzo PS, Bíró T, Szállási Z, Mushinski JF, Blumberg PM. Both the catalytic and regulatory domains of protein kinase C chimeras modulate the proliferative properties of NIH 3T3 cells. The Journal of Biological Chemistry. 272: 28793-9. PMID 9353351 DOI: 10.1074/Jbc.272.45.28793 |
0.324 |
|
1997 |
Acs P, Bögi K, Lorenzo PS, Marquez AM, Bíró T, Szállási Z, Blumberg PM. The catalytic domain of protein kinase C chimeras modulates the affinity and targeting of phorbol ester-induced translocation. The Journal of Biological Chemistry. 272: 22148-53. PMID 9268359 DOI: 10.1074/Jbc.272.35.22148 |
0.321 |
|
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