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Xiaozhou Luo, Ph.D. - Publications

Affiliations: 
Scripps Research Institute, La Jolla, La Jolla, CA, United States 
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40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2025 Zhao R, Zhang Y, Ruan B, Zhang H, Lv N, Li J, Yang YR, Luo X, Lu H. Nanourchin-like Uricase-Poly(-proline) Conjugate with Retained Enzymatic Activity, Mitigated Immunogenicity, and Sustained Efficacy Upon Repeated Administrations. Angewandte Chemie (International Ed. in English). e202425559. PMID 40042247 DOI: 10.1002/anie.202425559  0.414
2024 Huang Y, Zhang P, Wang H, Chen Y, Liu T, Luo X. Genetic Code Expansion: Recent Developments and Emerging Applications. Chemical Reviews. PMID 39737807 DOI: 10.1021/acs.chemrev.4c00216  0.34
2024 Yang T, Chen Y, Luo X, Keasling JD, Fan K, Pan G. A Simple and Effective Strategy for the Development of Robust Promoter-Centric Gene Expression Tools. Acs Synthetic Biology. PMID 39120429 DOI: 10.1021/acssynbio.4c00092  0.408
2024 Wang X, Chen N, Cruz-Morales P, Zhong B, Zhang Y, Wang J, Xiao Y, Fu X, Lin Y, Acharya S, Li Z, Deng H, Sun Y, Bai L, Tang X, ... ... Luo X, et al. Elucidation of genes enhancing natural product biosynthesis through co-evolution analysis. Nature Metabolism. PMID 38609677 DOI: 10.1038/s42255-024-01024-9  0.362
2024 Deng H, Yu H, Deng Y, Qiu Y, Li F, Wang X, He J, Liang W, Lan Y, Qiao L, Zhang Z, Zhang Y, Keasling JD, Luo X. Pathway Evolution Through a Bottlenecking-Debottlenecking Strategy and Machine Learning-Aided Flux Balancing. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2306935. PMID 38321783 DOI: 10.1002/advs.202306935  0.396
2023 Yu H, Deng H, He J, Keasling JD, Luo X. UniKP: a unified framework for the prediction of enzyme kinetic parameters. Nature Communications. 14: 8211. PMID 38081905 DOI: 10.1038/s41467-023-44113-1  0.374
2023 Li F, Chen Q, Deng H, Ye S, Chen R, Keasling JD, Luo X. One-pot selective biosynthesis of Tyrian purple in Escherichia coli. Metabolic Engineering. PMID 38000548 DOI: 10.1016/j.ymben.2023.11.003  0.418
2023 Zhang Y, Guo J, Gao P, Yan W, Shen J, Luo X, Keasling JD. Development of an efficient yeast platform for cannabigerolic acid biosynthesis. Metabolic Engineering. 80: 232-240. PMID 37890610 DOI: 10.1016/j.ymben.2023.10.004  0.466
2023 Yang J, Liu Y, Zhong D, Xu L, Gao H, Keasling JD, Luo X, Chou HH. Combinatorial optimization and spatial remodeling of CYPs to control product profile. Metabolic Engineering. PMID 37703999 DOI: 10.1016/j.ymben.2023.09.004  0.616
2023 Zhao X, Wu Y, Feng T, Shen J, Lu H, Zhang Y, Chou HH, Luo X, Keasling JD. Dynamic upregulation of the rate-limiting enzyme for valerolactam biosynthesis in Corynebacterium glutamicum. Metabolic Engineering. PMID 36933819 DOI: 10.1016/j.ymben.2023.02.005  0.628
2021 Xiao R, Zhao L, Ma H, Liu Q, Qin H, Luo X, Xuan W. Toward an Orthogonal Protein Lysine Acylation and Deacylation System. Chembiochem : a European Journal of Chemical Biology. PMID 34904351 DOI: 10.1002/cbic.202100551  0.641
2021 Deng J, Wu Y, Zheng Z, Chen N, Luo X, Tang H, Keasling JD. A synthetic promoter system for well-controlled protein expression with different carbon sources in Saccharomyces cerevisiae. Microbial Cell Factories. 20: 202. PMID 34663323 DOI: 10.1186/s12934-021-01691-3  0.432
2021 Xia Y, Li X, Yang L, Luo X, Shen W, Cao Y, Peplowski L, Chen X. Development of thermostable sucrose phosphorylase by semi-rational design for efficient biosynthesis of alpha-D-glucosylglycerol. Applied Microbiology and Biotechnology. PMID 34542685 DOI: 10.1007/s00253-021-11551-0  0.331
2021 Liu T, Wang Y, Chen X, Cai W, Tan L, Yu Y, Han B, Li Y, Xie Y, Su Y, Luo X. Expanding the structure diversity of protein building blocks with biosynthesized noncanonical amino acids from aromatic thiols. Angewandte Chemie (International Ed. in English). PMID 33570250 DOI: 10.1002/anie.202014540  0.423
2020 Tang H, Wu Y, Deng J, Chen N, Zheng Z, Wei Y, Luo X, Keasling JD. Promoter Architecture and Promoter Engineering in . Metabolites. 10. PMID 32781665 DOI: 10.3390/Metabo10080320  0.384
2020 Luo X, Reiter MA, d'Espaux L, Wong J, Denby CM, Lechner A, Zhang Y, Grzybowski AT, Harth S, Lin W, Lee H, Yu C, Shin J, Deng K, Benites VT, et al. Author Correction: Complete biosynthesis of cannabinoids and their unnatural analogues in yeast. Nature. 580: E2. PMID 32269333 DOI: 10.1038/S41586-020-2109-Z  0.423
2019 Luo X, Reiter MA, d'Espaux L, Wong J, Denby CM, Lechner A, Zhang Y, Grzybowski AT, Harth S, Lin W, Lee H, Yu C, Shin J, Deng K, Benites VT, et al. Complete biosynthesis of cannabinoids and their unnatural analogues in yeast. Nature. PMID 30814733 DOI: 10.1038/S41586-019-0978-9  0.544
2018 Supekova L, Zambaldo C, Choi S, Lim R, Luo X, Kazane SA, Young TS, Schultz PG. The genetic incorporation of p-azidomethyl-l-phenylalanine into proteins in yeast. Bioorganic & Medicinal Chemistry Letters. PMID 29625824 DOI: 10.1016/J.Bmcl.2018.03.055  0.77
2018 Yao A, Reed SA, Koh M, Yu C, Luo X, Mehta AP, Schultz PG. Progress toward a reduced phage genetic code. Bioorganic & Medicinal Chemistry. PMID 29609949 DOI: 10.1016/J.Bmc.2018.03.035  0.752
2018 Yang P, Zou H, Lee C, Muppidi A, Chao E, Fu Q, Luo X, Wang D, Schultz PG, Shen W. A Stapled, Long-Acting Glucagon-like Peptide 2 Analog with Efficacy in Dextran Sodium Sulfate-Induced Mouse Colitis Models. Journal of Medicinal Chemistry. PMID 29528634 DOI: 10.1021/Acs.Jmedchem.7B00768  0.716
2017 Du J, Cao Y, Liu Y, Wang Y, Zhang Y, Fu G, Zhang Y, Lu L, Luo X, Kim CH, Schultz PG, Wang F. Engineering Bifunctional Antibodies with Constant Region Fusion Architectures. Journal of the American Chemical Society. PMID 29186655 DOI: 10.1021/Jacs.7B09641  0.745
2017 Zambaldo C, Luo X, Mehta AP, Schultz PG. Recombinant Macrocyclic Lanthipeptides Incorporating Non-Canonical Amino Acids. Journal of the American Chemical Society. PMID 28809560 DOI: 10.1021/Jacs.7B04159  0.794
2017 Luo X, Fu G, Wang RE, Zhu X, Zambaldo C, Liu R, Liu T, Lyu X, Du J, Xuan W, Yao A, Reed SA, Kang M, Zhang Y, Guo H, et al. Genetically encoding phosphotyrosine and its nonhydrolyzable analog in bacteria. Nature Chemical Biology. PMID 28604693 DOI: 10.1038/Nchembio.2405  0.686
2017 Liu T, Jia P, Ma H, Reed SA, Luo X, Larman HB, Schultz PG. Construction and Screening of a Lentiviral Secretome Library. Cell Chemical Biology. PMID 28602759 DOI: 10.1016/J.Chembiol.2017.05.017  0.771
2016 Wang RE, Wang Y, Zhang Y, Gabrelow C, Zhang Y, Chi V, Fu Q, Luo X, Wang D, Joseph S, Johnson K, Chatterjee AK, Wright TM, Nguyen-Tran VT, Teijaro J, et al. Rational design of a Kv1.3 channel-blocking antibody as a selective immunosuppressant. Proceedings of the National Academy of Sciences of the United States of America. 113: 11501-11506. PMID 27663736 DOI: 10.1073/Pnas.1612803113  0.765
2016 Luo X, Wang TA, Zhang Y, Wang F, Schultz PG. Stabilizing Protein Motifs with a Genetically Encoded Metal-Ion Chelator. Cell Chemical Biology. 23: 1098-1102. PMID 27662253 DOI: 10.1016/J.Chembiol.2016.08.007  0.65
2016 Ablikim M, Achasov MN, Ahmed S, Ai XC, Albayrak O, Albrecht M, Ambrose DJ, Amoroso A, An FF, An Q, Bai JZ, Baldini Ferroli R, Ban Y, Bennett DW, Bennett JV, ... ... Luo XL, et al. Observation of an Anomalous Line Shape of the η^{'}π^{+}π^{-} Mass Spectrum near the pp[over ¯] Mass Threshold in J/ψ→γη^{'}π^{+}π^{-}. Physical Review Letters. 117: 042002. PMID 27494467 DOI: 10.1103/Physrevlett.117.042002  0.575
2016 Zuo L, Tan Y, Li CR, Wang Z, Wang K, Zhang X, Lin X, Chen X, Zhong C, Wang X, Wang J, Lu L, Luo X. Associations of rare nicotinic cholinergic receptor gene variants to nicotine and alcohol dependence. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 27473937 DOI: 10.1002/ajmg.b.32476  0.553
2016 Xuan W, Li J, Luo X, Schultz PG. Genetic Incorporation of a Reactive Isothiocyanate Group into Proteins. Angewandte Chemie (International Ed. in English). PMID 27418387 DOI: 10.1002/Anie.201604891  0.802
2016 Ablikim M, Achasov MN, Ai XC, Albayrak O, Albrecht M, Ambrose DJ, Amoroso A, An FF, An Q, Bai JZ, Baldini Ferroli R, Ban Y, Bennett DW, Bennett JV, Bertani M, ... ... Luo XL, et al. Observation of h_{c} Radiative Decay h_{c}→γη^{'} and Evidence for h_{c}→γη. Physical Review Letters. 116: 251802. PMID 27391715 DOI: 10.1103/Physrevlett.116.251802  0.573
2016 Liu T, Wang Y, Luo X, Li J, Reed SA, Xiao H, Young TS, Schultz PG. Enhancing protein stability with extended disulfide bonds. Proceedings of the National Academy of Sciences of the United States of America. 113: 5910-5. PMID 27162342 DOI: 10.1073/Pnas.1605363113  0.771
2016 Cao Y, Rodgers DT, Du J, Ahmad I, Hampton EN, Ma JS, Mazagova M, Choi SH, Yun HY, Xiao H, Yang P, Luo X, Lim RK, Pugh HM, Wang F, et al. Design of Switchable Chimeric Antigen Receptor T Cells Targeting Breast Cancer. Angewandte Chemie (International Ed. in English). 55: 7520-4. PMID 27145250 DOI: 10.1002/Anie.201601902  0.724
2016 Yang PY, Zou H, Chao E, Sherwood L, Nunez V, Keeney M, Ghartey-Tagoe E, Ding Z, Quirino H, Luo X, Welzel G, Chen G, Singh P, Woods AK, Schultz PG, et al. Engineering a long-acting, potent GLP-1 analog for microstructure-based transdermal delivery. Proceedings of the National Academy of Sciences of the United States of America. 113: 4140-5. PMID 27035989 DOI: 10.1073/Pnas.1601653113  0.722
2016 Luo X, Zambaldo C, Liu T, Zhang Y, Xuan W, Wang C, Reed SA, Yang PY, Wang RE, Javahishvili T, Schultz PG, Young TS. Recombinant thiopeptides containing noncanonical amino acids. Proceedings of the National Academy of Sciences of the United States of America. 113: 3615-20. PMID 26976568 DOI: 10.1073/Pnas.1602733113  0.749
2015 Luo X, Liu T, Wang Y, Jia H, Zhang Y, Caballero D, Du J, Wang RE, Wang D, Schultz PG, Wang F. An Epitope-Specific Respiratory Syncytial Virus Vaccine Based on an Antibody Scaffold. Angewandte Chemie (International Ed. in English). 54: 14531-4. PMID 26434555 DOI: 10.1002/Anie.201507928  0.683
2015 Liu T, Du J, Luo X, Schultz PG, Wang F. Homogeneously modified immunoglobulin domains for therapeutic application. Current Opinion in Chemical Biology. 28: 66-74. PMID 26117722 DOI: 10.1016/J.Cbpa.2015.06.007  0.539
2015 Harbut MB, Vilchèze C, Luo X, Hensler ME, Guo H, Yang B, Chatterjee AK, Nizet V, Jacobs WR, Schultz PG, Wang F. Auranofin exerts broad-spectrum bactericidal activities by targeting thiol-redox homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 112: 4453-8. PMID 25831516 DOI: 10.1073/Pnas.1504022112  0.569
2015 Liu T, Fu G, Luo X, Liu Y, Wang Y, Wang RE, Schultz PG, Wang F. Rational design of antibody protease inhibitors. Journal of the American Chemical Society. 137: 4042-5. PMID 25775396 DOI: 10.1021/Ja5130786  0.705
2015 Wang RE, Liu T, Wang Y, Cao Y, Du J, Luo X, Deshmukh V, Kim CH, Lawson BR, Tremblay MS, Young TS, Kazane SA, Wang F, Schultz PG. An immunosuppressive antibody-drug conjugate. Journal of the American Chemical Society. 137: 3229-32. PMID 25699419 DOI: 10.1021/Jacs.5B00620  0.744
2015 Liu T, Zhang Y, Liu Y, Wang Y, Jia H, Kang M, Luo X, Caballero D, Gonzalez J, Sherwood L, Nunez V, Wang D, Woods A, Schultz PG, Wang F. Functional human antibody CDR fusions as long-acting therapeutic endocrine agonists. Proceedings of the National Academy of Sciences of the United States of America. 112: 1356-61. PMID 25605877 DOI: 10.1073/Pnas.1423668112  0.784
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