| Year |
Citation |
Score |
| 2020 |
Gawrys O, Husková Z, Baranowska I, Walkowska A, Sadowski J, Kikerlová S, Vaňourková Z, Honetschlägerová Z, Škaroupková P, Červenka L, Falck JR, Imig JD, Kompanowska-Jezierska E. Combined treatment with epoxyeicosatrienoic acid analog and 20-hydroxyeicosatetraenoic acid antagonist provides substantial hypotensive effect in spontaneously hypertensive rats. Journal of Hypertension. PMID 32384390 DOI: 10.1097/Hjh.0000000000002462 |
0.398 |
|
| 2020 |
Guo Z, Lei J, Wu S, Molina-Vega J, Cervantes P, Rom'Mand AR, Mijangos DCC, Falck JR, Lange C, Wang J, Potter DA. Abstract 4372: Metformin inhibits nuclear localization of estrogen receptor alpha in breast cancer cells, in part, by inhibition of CYP-mediated epoxyeicosatrienoic acid (EET) biosynthesis Epidemiology. 80: 4372-4372. DOI: 10.1158/1538-7445.Am2020-4372 |
0.308 |
|
| 2020 |
Walkowska A, Sadowski J, Cervenka L, Falck JR, Kompanowska-Jezierska E. Acute hypotensive effect of EET‐A, a stable analog of epoxyeicosatrienic acid (EET), in spontaneously hypertensive rats: dependence on endogenous EETs activity The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.08828 |
0.349 |
|
| 2020 |
Gawrys O, Walkowska A, Kompanowska-Jezierska E, Husková Z, Honetschlägerová Z, Falck J, Imig J, Červenka L. Effective Antihypertensive Treatment with Epoxyeicosatrienoic Acid Analog (EET‐A) and 20‐HETE Antagonist (AAA) of Spontaneously Hypertensive Rats (SHR) The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.02103 |
0.327 |
|
| 2019 |
Adebesin AM, Wesser T, Vijaykumar J, Konkel A, Paudyal M, Lossie J, Zhu C, Westphal C, Puli N, Fischer R, Schunck WH, Falck JR. Development of Robust 17(R),18(S)-Epoxyeicosatetraenoic Acid (17,18-EEQ) Analogs as Potential Clinical Antiarrhythmic Agents. Journal of Medicinal Chemistry. PMID 31693857 DOI: 10.1021/Acs.Jmedchem.9B00952 |
0.341 |
|
| 2019 |
Dakarapu R, Errabelli R, Manthati VL, Michael Adebesin A, Barma DK, Barma D, Garcia V, Zhang F, Laniado Schwartzman M, Falck JR. 19-Hydroxyeicosatetraenoic acid analogs: Antagonism of 20-hydroxyeicosatetraenoic acid-induced vascular sensitization and hypertension. Bioorganic & Medicinal Chemistry Letters. 126616. PMID 31439380 DOI: 10.1016/J.Bmcl.2019.08.020 |
0.407 |
|
| 2019 |
Hoff U, Bubalo G, Fechner M, Blum M, Zhu Y, Pohlmann A, Hentschel J, Arakelyan K, Seeliger E, Flemming B, Gürgen D, Rothe M, Niendorf T, Manthati VL, Falck JR, et al. A synthetic epoxyeicosatrienoic acid analog prevents the initiation of ischemic acute kidney injury. Acta Physiologica (Oxford, England). e13297. PMID 31077555 DOI: 10.1111/Apha.13297 |
0.342 |
|
| 2019 |
Chen L, Tang S, Zhang FF, Garcia V, Falck JR, Laniado Schwartzman M, Arbab AS, Guo A. CYP4A/20-HETE Regulates Ischemia-induced Neovascularization via Its Actions on Endothelial Progenitor and Preexisting Endothelial Cells. American Journal of Physiology. Heart and Circulatory Physiology. PMID 30951365 DOI: 10.1152/Ajpheart.00690.2018 |
0.335 |
|
| 2019 |
Song CY, Shin JS, Lew J, Falck J, Malik K. Abstract P2029: Cytochrome P450 (CYP) 1B1-Estradiol Metabolite 2-Methoxyestradiol Protects Against Angiotensin II-induced Hypertension By Inhibiting CYP4A1 Expression 20-Hydroxyeicosatetraenoic Acid (20-HETE) Production In The Female Mice Hypertension. 74. DOI: 10.1161/Hyp.74.Suppl_1.P2029 |
0.361 |
|
| 2018 |
Capdevila JH, Falck JR. The Arachidonic Acid Monooxygenase. From Biochemical Curiosity to Physiological/Pathophysiological Significance. Journal of Lipid Research. PMID 30154230 DOI: 10.1194/Jlr.R087882 |
0.381 |
|
| 2018 |
Sedláková L, Kikerlová S, Husková Z, Červenková L, Čertíková Chábová V, Zicha J, Falck JR, Imig JD, Kompanowska-Jezierska E, Sadowski J, Krátký V, Červenka L, Kopkan L. 20-Hydroxyeicosatetraenoic acid antagonist attenuates the development of malignant hypertension and reverses it once established: a study in Cyp1a1-Ren-2 transgenic rats. Bioscience Reports. PMID 30054426 DOI: 10.1042/Bsr20171496 |
0.306 |
|
| 2018 |
Zhang X, El Demerdash N, Falck JR, Munnuri S, Koehler RC, Yang ZJ. The contribution of TRPV1 channel to 20-HETE-Aggravated ischemic neuronal injury. Prostaglandins & Other Lipid Mediators. 137: 63-68. PMID 30041768 DOI: 10.1016/J.Prostaglandins.2018.07.001 |
0.302 |
|
| 2018 |
Sausville LN, Gangadhariah M, Chiusa M, Mei S, Wei S, Zent R, Luther JM, Shuey MM, Capdevila JH, Falck JR, Guengerich FP, Williams SM, Pozzi A. The cytochrome P450 slow metabolizers CYP2C9*2 and CYP2C9*3 directly regulate tumorigenesis via reduced epoxyeicosatrienoic acid production. Cancer Research. PMID 30012669 DOI: 10.1158/0008-5472.Can-17-3977 |
0.334 |
|
| 2018 |
Park SK, Herrnreiter A, Pfister SL, Gauthier KM, Falck BA, Falck JR, Campbell WB. GPR40 is a Low Affinity Epoxyeicosatrienoic Acid Receptor in Vascular Cells. The Journal of Biological Chemistry. PMID 29777058 DOI: 10.1074/Jbc.Ra117.001297 |
0.375 |
|
| 2018 |
Červenka L, Husková Z, Kopkan L, Kikerlová S, Sedláková L, Vaňourková Z, Alánová P, Kolář F, Hammock BD, Hwang SH, Imig JD, Falck JR, Sadowski J, Kompanowska-Jezierska E, Neckář J. Two pharmacological epoxyeicosatrienoic acid-enhancing therapies are effectively antihypertensive and reduce the severity of ischemic arrhythmias in rats with angiotensin II-dependent hypertension. Journal of Hypertension. PMID 29570510 DOI: 10.1097/Hjh.0000000000001708 |
0.316 |
|
| 2018 |
Han X, Zhao X, Lan X, Li Q, Gao Y, Liu X, Wan J, Yang Z, Chen X, Zang W, Guo AM, Falck JR, Koehler RC, Wang J. 20-HETE synthesis inhibition promotes cerebral protection after intracerebral hemorrhage without inhibiting angiogenesis. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X18762645. PMID 29485354 DOI: 10.1177/0271678X18762645 |
0.313 |
|
| 2018 |
Kriska T, Thomas MJ, Falck JR, Campbell WB. DEACTIVATION OF 12(S)-HETE THROUGH (ω-1)-HYDROXYLATION AND β-OXIDATION IN ALTERNATIVELY ACTIVATED MACROPHAGES. Journal of Lipid Research. PMID 29472381 DOI: 10.1194/Jlr.M081448 |
0.305 |
|
| 2018 |
Soler A, Hunter I, Joseph G, Hutcheson R, Hutcheson B, Yang J, Zhang FF, Joshi SR, Bradford C, Gotlinger KH, Maniyar R, Falck JR, Proctor S, Schwartzman ML, Gupte SA, et al. Elevated 20-HETE in metabolic syndrome regulates arterial stiffness and systolic hypertension via MMP12 activation. Journal of Molecular and Cellular Cardiology. PMID 29428638 DOI: 10.1016/J.Yjmcc.2018.02.005 |
0.311 |
|
| 2017 |
Campbell WB, Imig JD, Schmitz JM, Falck JR. Orally Active Epoxyeicosatrienoic Acid Analogs. Journal of Cardiovascular Pharmacology. PMID 28937442 DOI: 10.1097/Fjc.0000000000000523 |
0.341 |
|
| 2017 |
Guo Z, Sevrioukova IF, Denisov IG, Zhang X, Chiu TL, Thomas DG, Hanse EA, Cuellar RAD, Grinkova YV, Langenfeld VW, Swedien DS, Stamschror JD, Alvarez J, Luna F, Galván A, ... ... Falck JR, et al. Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria. Cell Chemical Biology. PMID 28919040 DOI: 10.1016/J.Chembiol.2017.08.009 |
0.302 |
|
| 2017 |
Hasegawa E, Inafuku S, Mulki L, Okunuki Y, Yanai R, Smith KE, Kim CB, Klokman G, Bielenberg DR, Puli N, Falck JR, Husain D, Miller JW, Edin ML, Zeldin DC, et al. Cytochrome P450 monooxygenase lipid metabolites are significant second messengers in the resolution of choroidal neovascularization. Proceedings of the National Academy of Sciences of the United States of America. PMID 28827330 DOI: 10.1073/Pnas.1620898114 |
0.347 |
|
| 2017 |
Hanif A, Edin ML, Zeldin DC, Morisseau C, Falck JR, Nayeem MA. Vascular endothelial overexpression of human CYP2J2 (Tie2-CYP2J2 Tr) modulates cardiac oxylipin profiles and enhances coronary reactive hyperemia in mice. Plos One. 12: e0174137. PMID 28328948 DOI: 10.1371/Journal.Pone.0174137 |
0.361 |
|
| 2017 |
Garcia V, Gilani A, Shkolnik B, Pandey V, Zhang FF, Dakarapu R, Gandham SK, Reddy NR, Graves JP, Gruzdev A, Zeldin DC, Capdevila JH, Falck JR, Schwartzman ML. HETE Signals Through G Protein-Coupled Receptor GPR75 (Gq) to Affect Vascular Function and Trigger Hypertension. Circulation Research. PMID 28325781 DOI: 10.1161/Circresaha.116.310525 |
0.323 |
|
| 2017 |
Hanif A, Edin ML, Zeldin DC, Morisseau C, Falck JR, Nayeem MA. Vascular Endothelial Over-Expression of Human Soluble Epoxide Hydrolase (Tie2-sEH Tr) Attenuates Coronary Reactive Hyperemia in Mice: Role of Oxylipins and ω-Hydroxylases. Plos One. 12: e0169584. PMID 28056085 DOI: 10.1371/Journal.Pone.0169584 |
0.365 |
|
| 2016 |
Sporková A, Husková Z, Škaroupková P, Reddy NR, Falck JR, Sadowski J, Červenka L. Vasodilatory responses of renal interlobular arteries to epoxyeicosatrienoic acids analog are not enhanced in Ren-2 transgenic hypertensive rats: evidence against a role of direct vascular effects of epoxyeicosatrienoic acids in progression of experimental heart failure. Physiological Research. PMID 27782740 DOI: 10.33549/Physiolres.933350 |
0.338 |
|
| 2016 |
Paudyal MP, Adebesin AM, Burt SR, Ess DH, Ma Z, Kürti L, Falck JR. Dirhodium-catalyzed C-H arene amination using hydroxylamines. Science (New York, N.Y.). 353: 1144-7. PMID 27609890 DOI: 10.1126/Science.Aaf8713 |
0.608 |
|
| 2016 |
Jíchová Š, Kopkan L, Husková Z, Doleželová Š, Neckář J, Kujal P, Vernerová Z, Kramer HJ, Sadowski J, Kompanowska-Jezierska E, Reddy RN, Falck JR, Imig JD, Červenka L. Epoxyeicosatrienoic acid analog attenuates the development of malignant hypertension, but does not reverse it once established: a study in Cyp1a1-Ren-2 transgenic rats. Journal of Hypertension. PMID 27428043 DOI: 10.1097/Hjh.0000000000001029 |
0.326 |
|
| 2016 |
Yeboah MM, Khan MA, Chesnik MA, Sharma A, Paudyal MP, Falck JR, Imig JD. The Epoxyeicosatrienoic Acid Analog, PVPA, Ameliorates Cyclosporine-Induced Hypertension and Renal Injury in Rats. American Journal of Physiology. Renal Physiology. ajprenal.00288.2016. PMID 27358055 DOI: 10.1152/Ajprenal.00288.2016 |
0.354 |
|
| 2016 |
Savas U, Wei S, Hsu MH, Falck JR, Guengerich FP, Capdevila JH, Johnson EF. 20-Hydroxyeicosatetraenoic Acid (HETE) Dependent Hypertension in Human Cytochrome P450 (CYP) 4A11 Transgenic Mice: Normalization of Blood Pressure by Sodium Restriction, Hydrochlorothiazide, or Blockade of the Type 1 Angiotensin II Receptor. The Journal of Biological Chemistry. PMID 27298316 DOI: 10.1074/Jbc.M116.732297 |
0.328 |
|
| 2016 |
Sporková A, Reddy RN, Falck JR, Imig JD, Kopkan L, Sadowski J, Červenka L. Interlobular Arteries From 2-Kidney, 1-Clip Goldblatt Hypertensive Rats' Exhibit-Impaired Vasodilator Response to Epoxyeicosatrienoic Acids. The American Journal of the Medical Sciences. 351: 513-9. PMID 27140711 DOI: 10.1016/J.Amjms.2016.02.030 |
0.319 |
|
| 2016 |
Chen L, Joseph G, Zhang FF, Nguyen H, Jiang H, Gotlinger KH, Falck JR, Yang J, Schwartzman ML, Guo AM. 20-HETE contributes to ischemia-induced angiogenesis. Vascular Pharmacology. PMID 27084395 DOI: 10.1016/J.Vph.2016.04.002 |
0.313 |
|
| 2016 |
Khan MA, Fish BL, Wahl G, Sharma A, Falck JR, Paudyal M, Moulder JE, Imig JD, Cohen EP. Epoxyeicosatrienoic acid analog mitigates kidney injury in a rat model of radiation nephropathy. Clinical Science (London, England : 1979). PMID 26772189 DOI: 10.1042/Cs20150778 |
0.32 |
|
| 2016 |
Garcia V, Shkolnik B, Milhau L, Falck JR, Schwartzman ML. 20-HETE Activates the Transcription of Angiotensin-Converting Enzyme via Nuclear Factor-κB Translocation and Promoter Binding. The Journal of Pharmacology and Experimental Therapeutics. 356: 525-33. PMID 26699146 DOI: 10.1124/Jpet.115.229377 |
0.312 |
|
| 2015 |
Siangjong L, Goldman DH, Kriska T, Gauthier KM, Smyth EM, Puli N, Kumar G, Falck JR, Campbell WB. Vascular hepoxilin and trioxilins mediate vasorelaxation through TP receptor inhibition in mouse arteries. Acta Physiologica (Oxford, England). PMID 26666460 DOI: 10.1111/Apha.12642 |
0.34 |
|
| 2015 |
Zhou Y, Falck JR, Rothe M, Schunck WH, Menzel R. Role of CYP-eicosanoids in the regulation of pharyngeal pumping and food uptake in C. elegans. Journal of Lipid Research. PMID 26399467 DOI: 10.1194/Jlr.M061887 |
0.317 |
|
| 2015 |
Alánová P, Husková Z, Kopkan L, Sporková A, Jíchová Š, Neckář J, Imig JD, Klevstig M, Kolář F, Rami Reddy N, Falck JR, Sadowski J, Nishiyama A, Kramer HJ, Melenovský V, et al. Orally active epoxyeicosatrienoic acid analog does not exhibit antihypertensive and reno- or cardioprotective actions in two-kidney, one-clip Goldblatt hypertensive rats. Vascular Pharmacology. 73: 45-56. PMID 26304700 DOI: 10.1016/J.Vph.2015.08.013 |
0.312 |
|
| 2015 |
Capdevila JH, Wang W, Falck JR. Arachidonic acid monooxygenase: Genetic and biochemical approaches to physiological/pathophysiological relevance. Prostaglandins & Other Lipid Mediators. 120: 40-9. PMID 25986599 DOI: 10.1016/J.Prostaglandins.2015.05.004 |
0.339 |
|
| 2015 |
Cao J, Tsenovoy PL, Thompson EA, Falck JR, Touchon R, Sodhi K, Rezzani R, Shapiro JI, Abraham NG. Agonists of epoxyeicosatrienoic acids reduce infarct size and ameliorate cardiac dysfunction via activation of HO-1 and Wnt1 canonical pathway. Prostaglandins & Other Lipid Mediators. 116: 76-86. PMID 25677507 DOI: 10.1016/J.Prostaglandins.2015.01.002 |
0.315 |
|
| 2015 |
Jat JL, De SR, Kumar G, Adebesin AM, Gandham SK, Falck JR. Regio- and enantioselective catalytic monoepoxidation of conjugated dienes: synthesis of chiral allylic cis-epoxides. Organic Letters. 17: 1058-61. PMID 25668127 DOI: 10.1021/Acs.Orglett.5B00281 |
0.312 |
|
| 2015 |
Muroya Y, Fan F, Regner KR, Falck JR, Garrett MR, Juncos LA, Roman RJ. Deficiency in the Formation of 20-Hydroxyeicosatetraenoic Acid Enhances Renal Ischemia-Reperfusion Injury. Journal of the American Society of Nephrology : Jasn. PMID 25644108 DOI: 10.1681/Asn.2014090868 |
0.303 |
|
| 2015 |
Kibel A, Novak S, Cosic A, Mihaljevic Z, Falck JR, Drenjancevic I. Hyperbaric oxygenation modulates vascular reactivity to angiotensin-(1-7) in diabetic rats: Potential role of epoxyeicosatrienoic acids Diabetes and Vascular Disease Research. 12: 33-45. PMID 25326234 DOI: 10.1177/1479164114553424 |
0.308 |
|
| 2015 |
Bodduri VDV, Choi KM, Vaidya RR, Patil K, Chirumarry S, Jang K, Yoon YJ, Falck JR, Shin DS. An efficient iron catalyzed regioselective acylative cleavage of ethers: Scope and mechanism Tetrahedron Letters. 56: 7089-7093. DOI: 10.1016/J.Tetlet.2015.11.016 |
0.305 |
|
| 2014 |
Samokhvalov V, Vriend J, Jamieson KL, Akhnokh MK, Manne R, Falck JR, Seubert JM. PPARγ signaling is required for mediating EETs protective effects in neonatal cardiomyocytes exposed to LPS. Frontiers in Pharmacology. 5: 242. PMID 25426073 DOI: 10.3389/Fphar.2014.00242 |
0.324 |
|
| 2014 |
Sato Y, Sato W, Maruyama S, Wilcox CS, Falck JR, Masuda T, Kosugi T, Kojima H, Maeda K, Furuhashi K, Ando M, Imai E, Matsuo S, Kadomatsu K. Midkine Regulates BP through Cytochrome P450-Derived Eicosanoids. Journal of the American Society of Nephrology : Jasn. PMID 25377079 DOI: 10.1681/Asn.2013121259 |
0.306 |
|
| 2014 |
De SR, Kumar G, Jat JL, Birudaraju S, Lu B, Manne R, Puli N, Adebesin AM, Falck JR. Regio- and stereoselective monoepoxidation of dienes using methyltrioxorhenium: synthesis of allylic epoxides. The Journal of Organic Chemistry. 79: 10323-33. PMID 25321319 DOI: 10.1021/Jo501958D |
0.308 |
|
| 2014 |
Li J, Stier CT, Chander PN, Manthati VL, Falck JR, Carroll MA. Pharmacological manipulation of arachidonic acid-epoxygenase results in divergent effects on renal damage. Frontiers in Pharmacology. 5: 187. PMID 25177296 DOI: 10.3389/Fphar.2014.00187 |
0.32 |
|
| 2014 |
Keller J, Ellieva A, Ma DK, Ju J, Nehk E, Konkel A, Falck JR, Schunck WH, Menzel R. CYP-13A12 of the nematode Caenorhabditis elegans is a PUFA-epoxygenase involved in behavioural response to reoxygenation. The Biochemical Journal. 464: 61-71. PMID 25138176 DOI: 10.1042/Bj20140848 |
0.367 |
|
| 2014 |
Falck JR, Koduru SR, Mohapatra S, Manne R, Atcha KR, Atcha R, Manthati VL, Capdevila JH, Christian S, Imig JD, Campbell WB. 14,15-Epoxyeicosa-5,8,11-trienoic Acid (14,15-EET) surrogates: carboxylate modifications. Journal of Medicinal Chemistry. 57: 6965-72. PMID 25119815 DOI: 10.1021/Jm500262M |
0.371 |
|
| 2014 |
Nithipatikom K, Endsley MP, Pfeiffer AW, Falck JR, Campbell WB. A novel activity of microsomal epoxide hydrolase: metabolism of the endocannabinoid 2-arachidonoylglycerol. Journal of Lipid Research. 55: 2093-102. PMID 24958911 DOI: 10.1194/Jlr.M051284 |
0.306 |
|
| 2014 |
Ding Y, Frömel T, Popp R, Falck JR, Schunck WH, Fleming I. The biological actions of 11,12-epoxyeicosatrienoic acid in endothelial cells are specific to the R/S-enantiomer and require the G(s) protein. The Journal of Pharmacology and Experimental Therapeutics. 350: 14-21. PMID 24763066 DOI: 10.1124/Jpet.114.214254 |
0.34 |
|
| 2014 |
Hye Khan MA, Pavlov TS, Christain SV, Neckář J, Staruschenko A, Gauthier KM, Capdevila JH, Falck JR, Campbell WB, Imig JD. Epoxyeicosatrienoic acid analogue lowers blood pressure through vasodilation and sodium channel inhibition. Clinical Science (London, England : 1979). 127: 463-74. PMID 24707975 DOI: 10.1042/Cs20130479 |
0.324 |
|
| 2014 |
Cheng J, Edin ML, Hoopes SL, Li H, Bradbury JA, Graves JP, DeGraff LM, Lih FB, Garcia V, Shaik JS, Tomer KB, Flake GP, Falck JR, Lee CR, Poloyac SM, et al. Vascular characterization of mice with endothelial expression of cytochrome P450 4F2. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 2915-31. PMID 24668751 DOI: 10.1096/Fj.13-241927 |
0.339 |
|
| 2014 |
Chen L, Ackerman R, Saleh M, Gotlinger KH, Kessler M, Mendelowitz LG, Falck JR, Arbab AS, Scicli AG, Schwartzman ML, Yang J, Guo AM. 20-HETE regulates the angiogenic functions of human endothelial progenitor cells and contributes to angiogenesis in vivo. The Journal of Pharmacology and Experimental Therapeutics. 348: 442-51. PMID 24403517 DOI: 10.1124/Jpet.113.210120 |
0.314 |
|
| 2014 |
Jat JL, Paudyal MP, Gao H, Xu QL, Yousufuddin M, Devarajan D, Ess DH, Kürti L, Falck JR. Direct stereospecific synthesis of unprotected N-H and N-Me aziridines from olefins. Science (New York, N.Y.). 343: 61-5. PMID 24385626 DOI: 10.1126/Science.1245727 |
0.596 |
|
| 2014 |
Capdevila JH, Pidkovka N, Mei S, Gong Y, Falck JR, Imig JD, Harris RC, Wang W. The Cyp2c44 epoxygenase regulates epithelial sodium channel activity and the blood pressure responses to increased dietary salt. The Journal of Biological Chemistry. 289: 4377-86. PMID 24368771 DOI: 10.1074/Jbc.M113.508416 |
0.309 |
|
| 2014 |
Frink LA, Khan MA, Kürti L, Falck JR, Paudyal MP, Jat JL, Armstrong DW. Enantiomeric Separations of N–H/N–Me Aziridines Utilizing GC and HPLC Chromatographia. 77: 1607-1612. DOI: 10.1007/S10337-014-2776-8 |
0.576 |
|
| 2013 |
Fan F, Sun CW, Maier KG, Williams JM, Pabbidi MR, Didion SP, Falck JR, Zhuo J, Roman RJ. 20-Hydroxyeicosatetraenoic acid contributes to the inhibition of K+ channel activity and vasoconstrictor response to angiotensin II in rat renal microvessels. Plos One. 8: e82482. PMID 24324797 DOI: 10.1371/Journal.Pone.0082482 |
0.315 |
|
| 2013 |
Samokhvalov V, Alsaleh N, El-Sikhry HE, Jamieson KL, Chen CB, Lopaschuk DG, Carter C, Light PE, Manne R, Falck JR, Seubert JM. Epoxyeicosatrienoic acids protect cardiac cells during starvation by modulating an autophagic response. Cell Death & Disease. 4: e885. PMID 24157879 DOI: 10.1038/Cddis.2013.418 |
0.334 |
|
| 2013 |
Hye Khan MA, Neckár J, Manthati V, Errabelli R, Pavlov TS, Staruschenko A, Falck JR, Imig JD. Orally active epoxyeicosatrienoic acid analog attenuates kidney injury in hypertensive Dahl salt-sensitive rat. Hypertension. 62: 905-13. PMID 23980070 DOI: 10.1161/Hypertensionaha.113.01949 |
0.303 |
|
| 2013 |
Kriska T, Cepura C, Siangjong L, Wan TC, Auchampach JA, Shaish A, Haratz D, Kumar G, Falck JR, Gauthier KM, Campbell WB. Effect of human 15-lipoxygenase-1 metabolites on vascular function in mouse mesenteric arteries and hearts. Prostaglandins & Other Lipid Mediators. 106: 8-15. PMID 23872364 DOI: 10.1016/J.Prostaglandins.2013.07.002 |
0.319 |
|
| 2013 |
Ding Y, Wu CC, Garcia V, Dimitrova I, Weidenhammer A, Joseph G, Zhang F, Manthati VL, Falck JR, Capdevila JH, Schwartzman ML. 20-HETE induces remodeling of renal resistance arteries independent of blood pressure elevation in hypertension. American Journal of Physiology. Renal Physiology. 305: F753-63. PMID 23825080 DOI: 10.1152/Ajprenal.00292.2013 |
0.34 |
|
| 2013 |
Brown NJ, Falck JR. Introduction. P450 metabolites of arachidonic acid--from biochemistry to therapy. Prostaglandins & Other Lipid Mediators. 104: 1. PMID 23809194 DOI: 10.1016/J.Prostaglandins.2013.06.003 |
0.321 |
|
| 2013 |
Li Y, Zhao H, Wang Y, Zheng H, Yu W, Chai H, Zhang J, Falck JR, Guo AM, Yue J, Peng R, Yang J. Isoliquiritigenin induces growth inhibition and apoptosis through downregulating arachidonic acid metabolic network and the deactivation of PI3K/Akt in human breast cancer. Toxicology and Applied Pharmacology. 272: 37-48. PMID 23747687 DOI: 10.1016/J.Taap.2013.05.031 |
0.309 |
|
| 2013 |
Tunctan B, Korkmaz B, Sari AN, Kacan M, Unsal D, Serin MS, Buharalioglu CK, Sahan-Firat S, Cuez T, Schunck WH, Manthati VL, Falck JR, Malik KU. Contribution of iNOS/sGC/PKG pathway, COX-2, CYP4A1, and gp91 phox to the protective effect of 5,14-HEDGE, a 20-HETE mimetic, against vasodilation, hypotension, tachycardia, and inflammation in a rat model of septic shock Nitric Oxide - Biology and Chemistry. 33: 18-41. PMID 23684565 DOI: 10.1016/J.Niox.2013.05.001 |
0.333 |
|
| 2013 |
Wu CC, Mei S, Cheng J, Ding Y, Weidenhammer A, Garcia V, Zhang F, Gotlinger K, Manthati VL, Falck JR, Capdevila JH, Schwartzman ML. Androgen-sensitive hypertension associates with upregulated vascular CYP4A12-20-HETE synthase. Journal of the American Society of Nephrology : Jasn. 24: 1288-96. PMID 23641057 DOI: 10.1681/Asn.2012070714 |
0.324 |
|
| 2013 |
Khan MA, Liu J, Kumar G, Skapek SX, Falck JR, Imig JD. Novel orally active epoxyeicosatrienoic acid (EET) analogs attenuate cisplatin nephrotoxicity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 2946-56. PMID 23603837 DOI: 10.1096/Fj.12-218040 |
0.307 |
|
| 2013 |
Ge Y, Murphy SR, Lu Y, Falck J, Liu R, Roman RJ. Endogenously produced 20-HETE modulates myogenic and TGF response in microperfused afferent arterioles. Prostaglandins & Other Lipid Mediators. 102: 42-8. PMID 23500064 DOI: 10.1016/J.Prostaglandins.2013.03.001 |
0.346 |
|
| 2013 |
Tunctan B, Korkmaz B, Sari AN, Kacan M, Unsal D, Serin MS, Buharalioglu CK, Sahan-Firat S, Cuez T, Schunck WH, Falck JR, Malik KU. 5,14-HEDGE, a 20-HETE mimetic, reverses hypotension and improves survival in a rodent model of septic shock: Contribution of soluble epoxide hydrolase, CYP2C23, MEK1/ERK1/2/IKKβ/IκB-α/NF-κB pathway, and proinflammatory cytokine formation Prostaglandins and Other Lipid Mediators. 102: 31-41. PMID 23454652 DOI: 10.1016/J.Prostaglandins.2013.01.005 |
0.301 |
|
| 2013 |
Kim DH, Puri N, Sodhi K, Falck JR, Abraham NG, Shapiro J, Schwartzman ML. Cyclooxygenase-2 dependent metabolism of 20-HETE increases adiposity and adipocyte enlargement in mesenchymal stem cell-derived adipocytes. Journal of Lipid Research. 54: 786-93. PMID 23293373 DOI: 10.1194/Jlr.M033894 |
0.346 |
|
| 2013 |
Tunctan B, Sari AN, Kacan M, Unsal D, Buharalioglu CK, Sahan-Firat S, Korkmaz B, Falck JR, Malik KU. NS-398 reverses hypotension in endotoxemic rats: Contribution of eicosanoids, NO, and peroxynitrite Prostaglandins and Other Lipid Mediators. 104: 93-108. PMID 22975359 DOI: 10.1016/J.Prostaglandins.2012.08.007 |
0.337 |
|
| 2013 |
Lukaszewicz KM, Falck JR, Manthati VL, Lombard JH. Introgression of Brown Norway CYP4A genes on to the Dahl salt-sensitive background restores vascular function in SS-5(BN) consomic rats. Clinical Science (London, England : 1979). 124: 333-42. PMID 22938512 DOI: 10.1042/Cs20120232 |
0.322 |
|
| 2013 |
Gross GJ, Hsu A, Gross ER, Falck JR, Nithipatikom K. Factors mediating remote preconditioning of trauma in the rat heart: central role of the cytochrome p450 epoxygenase pathway in mediating infarct size reduction. Journal of Cardiovascular Pharmacology and Therapeutics. 18: 38-45. PMID 22407888 DOI: 10.1177/1074248412437586 |
0.322 |
|
| 2012 |
Jiang H, Harrison FE, Jain K, Benjamin S, May JM, Graves JP, Zeldin DC, Falck JR, Hammock BD, McGiff JC. Vitamin C activation of the biosynthesis of epoxyeicosatrienoic acids. Advances in Bioscience and Biotechnology (Print). 3: 204-218. PMID 24660109 DOI: 10.4236/Abb.2012.33029 |
0.379 |
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| 2012 |
Zhu C, Li G, Ess DH, Falck JR, Kürti L. Elusive metal-free primary amination of arylboronic acids: synthetic studies and mechanism by density functional theory. Journal of the American Chemical Society. 134: 18253-6. PMID 23082853 DOI: 10.1021/Ja309637R |
0.614 |
|
| 2012 |
Tunctan B, Korkmaz B, Sari AN, Kacan M, Unsal D, Serin MS, Buharalioglu CK, Sahan-Firat S, Schunck WH, Falck JR, Malik KU. A novel treatment strategy for sepsis and septic shock based on the interactions between prostanoids, Nitric Oxide, and 20-Hydroxyeicosatetraenoic acid Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry. 11: 121-150. PMID 23013331 DOI: 10.2174/187152312803305759 |
0.321 |
|
| 2012 |
Decker M, Adamska M, Cronin A, Di Giallonardo F, Burgener J, Marowsky A, Falck JR, Morisseau C, Hammock BD, Gruzdev A, Zeldin DC, Arand M. EH3 (ABHD9): the first member of a new epoxide hydrolase family with high activity for fatty acid epoxides. Journal of Lipid Research. 53: 2038-45. PMID 22798687 DOI: 10.1194/Jlr.M024448 |
0.348 |
|
| 2012 |
Zhu C, Wang R, Falck JR. Mild and rapid hydroxylation of aryl/heteroaryl boronic acids and boronate esters with N-oxides. Organic Letters. 14: 3494-7. PMID 22731862 DOI: 10.1021/Ol301463C |
0.321 |
|
| 2012 |
Cheng J, Garcia V, Ding Y, Wu CC, Thakar K, Falck JR, Ramu E, Schwartzman ML. Induction of angiotensin-converting enzyme and activation of the renin-angiotensin system contribute to 20-hydroxyeicosatetraenoic acid-mediated endothelial dysfunction. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 1917-24. PMID 22723444 DOI: 10.1161/Atvbaha.112.248344 |
0.35 |
|
| 2012 |
Jacobs ER, Bodiga S, Ali I, Falck AM, Falck JR, Medhora M, Dhanasekaran A. Tissue protection and endothelial cell signaling by 20-HETE analogs in intact ex vivo lung slices. Experimental Cell Research. 318: 2143-52. PMID 22687879 DOI: 10.1016/J.Yexcr.2012.06.005 |
0.311 |
|
| 2012 |
Bukhari IA, Shah AJ, Gauthier KM, Walsh KA, Koduru SR, Imig JD, Falck JR, Campbell WB. 11,12,20-Trihydroxy-eicosa-8(Z)-enoic acid: a selective inhibitor of 11,12-EET-induced relaxations of bovine coronary and rat mesenteric arteries. American Journal of Physiology. Heart and Circulatory Physiology. 302: H1574-83. PMID 22307677 DOI: 10.1152/Ajpheart.01122.2011 |
0.373 |
|
| 2012 |
Renic M, Kumar SN, Gebremedhin D, Florence MA, Gerges NZ, Falck JR, Harder DR, Roman RJ. Protective effect of 20-HETE inhibition in a model of oxygen-glucose deprivation in hippocampal slice cultures. American Journal of Physiology. Heart and Circulatory Physiology. 302: H1285-93. PMID 22245774 DOI: 10.1152/Ajpheart.00340.2011 |
0.33 |
|
| 2012 |
Liu X, Li C, Falck JR, Harder DR, Koehler RC. Relative contribution of cyclooxygenases, epoxyeicosatrienoic acids, and pH to the cerebral blood flow response to vibrissal stimulation. American Journal of Physiology. Heart and Circulatory Physiology. 302: H1075-85. PMID 22198176 DOI: 10.1152/Ajpheart.00794.2011 |
0.328 |
|
| 2012 |
Liu Y, Zhang J, Yu L, Cao F, Rao J, Li J, Jiang C, Falck JR, Jacobs ER, Zhu D. A soluble epoxide hydrolase inhibitor--8-HUDE increases pulmonary vasoconstriction through inhibition of K(ATP) channels. Pulmonary Pharmacology & Therapeutics. 25: 69-76. PMID 22155000 DOI: 10.1016/J.Pupt.2011.11.005 |
0.319 |
|
| 2012 |
Ali I, Gruenloh S, Gao Y, Clough A, Falck JR, Medhora M, Jacobs ER. Protection by 20-5,14-HEDGE against surgically induced ischemia reperfusion lung injury in rats. The Annals of Thoracic Surgery. 93: 282-8. PMID 22115333 DOI: 10.1016/J.Athoracsur.2011.08.074 |
0.3 |
|
| 2011 |
Vanella L, Kim DH, Sodhi K, Barbagallo I, Burgess AP, Falck JR, Schwartzman ML, Abraham NG. Crosstalk between EET and HO-1 downregulates Bach1 and adipogenic marker expression in mesenchymal stem cell derived adipocytes. Prostaglandins & Other Lipid Mediators. 96: 54-62. PMID 21821145 DOI: 10.1016/J.Prostaglandins.2011.07.005 |
0.32 |
|
| 2011 |
Gauthier KM, Olson L, Harder A, Isbell M, Imig JD, Gutterman DD, Falck JR, Campbell WB. Soluble epoxide hydrolase contamination of specific catalase preparations inhibits epoxyeicosatrienoic acid vasodilation of rat renal arterioles. American Journal of Physiology. Renal Physiology. 301: F765-72. PMID 21753077 DOI: 10.1152/Ajprenal.00201.2011 |
0.363 |
|
| 2011 |
Li H, He A, Falck JR, Liebeskind LS. Stereocontrolled synthesis of α-amino-α′-alkoxy ketones by a copper-catalyzed cross-coupling of peptidic thiol esters and α-alkoxyalkylstannanes Organic Letters. 13: 3682-3685. PMID 21675755 DOI: 10.1021/Ol201330J |
0.338 |
|
| 2011 |
Zhu C, Falck JR. Alternative pathways for Heck intermediates: palladium-catalyzed oxyarylation of homoallylic alcohols. Angewandte Chemie (International Ed. in English). 50: 6626-9. PMID 21656881 DOI: 10.1002/Anie.201101857 |
0.327 |
|
| 2011 |
Liu X, Li C, Gebremedhin D, Hwang SH, Hammock BD, Falck JR, Roman RJ, Harder DR, Koehler RC. Epoxyeicosatrienoic acid-dependent cerebral vasodilation evoked by metabotropic glutamate receptor activation in vivo American Journal of Physiology - Heart and Circulatory Physiology. 301: H373-H381. PMID 21602473 DOI: 10.1152/Ajpheart.00745.2010 |
0.333 |
|
| 2011 |
Falck JR, Wallukat G, Puli N, Goli M, Arnold C, Konkel A, Rothe M, Fischer R, Müller DN, Schunck WH. 17(R),18(S)-epoxyeicosatetraenoic acid, a potent eicosapentaenoic acid (EPA) derived regulator of cardiomyocyte contraction: structure-activity relationships and stable analogues. Journal of Medicinal Chemistry. 54: 4109-18. PMID 21591683 DOI: 10.1021/Jm200132Q |
0.341 |
|
| 2011 |
Guo AM, Janic B, Sheng J, Falck JR, Roman RJ, Edwards PA, Arbab AS, Scicli AG. The cytochrome P450 4A/F-20-hydroxyeicosatetraenoic acid system: a regulator of endothelial precursor cells derived from human umbilical cord blood. The Journal of Pharmacology and Experimental Therapeutics. 338: 421-9. PMID 21527533 DOI: 10.1124/Jpet.111.179036 |
0.353 |
|
| 2011 |
Chen Y, Falck JR, Manthati VL, Jat JL, Campbell WB. 20-Iodo-14,15-epoxyeicosa-8(Z)-enoyl-3-azidophenylsulfonamide: photoaffinity labeling of a 14,15-epoxyeicosatrienoic acid receptor. Biochemistry. 50: 3840-8. PMID 21469660 DOI: 10.1021/Bi102070W |
0.322 |
|
| 2011 |
Jiang H, Quilley J, Doumad AB, Zhu AG, Falck JR, Hammock BD, Stier CT, Carroll MA. Increases in plasma trans-EETs and blood pressure reduction in spontaneously hypertensive rats. American Journal of Physiology. Heart and Circulatory Physiology. 300: H1990-6. PMID 21398593 DOI: 10.1152/Ajpheart.01267.2010 |
0.306 |
|
| 2011 |
Wu CC, Cheng J, Zhang FF, Gotlinger KH, Kelkar M, Zhang Y, Jat JL, Falck JR, Schwartzman ML. Androgen-dependent hypertension is mediated by 20-hydroxy-5,8,11,14-eicosatetraenoic acid-induced vascular dysfunction: role of inhibitor of kappaB Kinase. Hypertension. 57: 788-94. PMID 21321301 DOI: 10.1161/Hypertensionaha.110.161570 |
0.366 |
|
| 2011 |
Liu Y, Wang R, Li J, Rao J, Li W, Falck JR, Manthati VL, Medhora M, Jacobs ER, Zhu D. Stable EET urea agonist and soluble epoxide hydrolase inhibitor regulate rat pulmonary arteries through TRPCs. Hypertension Research : Official Journal of the Japanese Society of Hypertension. 34: 630-9. PMID 21307870 DOI: 10.1038/Hr.2011.5 |
0.329 |
|
| 2011 |
Kopf PG, Gauthier KM, Zhang DX, Falck JR, Campbell WB. Angiotensin II regulates adrenal vascular tone through zona glomerulosa cell-derived EETs and DHETs. Hypertension (Dallas, Tex. : 1979). 57: 323-9. PMID 21199991 DOI: 10.1161/Hypertensionaha.110.158311 |
0.313 |
|
| 2011 |
Gauthier KM, Goldman DH, Aggarwal NT, Chawengsub Y, Falck JR, Campbell WB. Role of arachidonic acid lipoxygenase metabolites in acetylcholine-induced relaxations of mouse arteries. American Journal of Physiology. Heart and Circulatory Physiology. 300: H725-35. PMID 21193584 DOI: 10.1152/Ajpheart.00696.2009 |
0.352 |
|
| 2011 |
Deng Y, Edin ML, Theken KN, Schuck RN, Flake GP, Kannon MA, DeGraff LM, Lih FB, Foley J, Bradbury JA, Graves JP, Tomer KB, Falck JR, Zeldin DC, Lee CR. Endothelial CYP epoxygenase overexpression and soluble epoxide hydrolase disruption attenuate acute vascular inflammatory responses in mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 703-13. PMID 21059750 DOI: 10.1096/Fj.10-171488 |
0.303 |
|
| 2011 |
Batchu SN, Lee SB, Qadhi RS, Chaudhary KR, El-Sikhry H, Kodela R, Falck JR, Seubert JM. Cardioprotective effect of a dual acting epoxyeicosatrienoic acid analogue towards ischaemia reperfusion injury. British Journal of Pharmacology. 162: 897-907. PMID 21039415 DOI: 10.1111/J.1476-5381.2010.01093.X |
0.348 |
|
| 2011 |
Hoff U, Lukitsch I, Chaykovska L, Ladwig M, Arnold C, Manthati VL, Fuller TF, Schneider W, Gollasch M, Muller DN, Flemming B, Seeliger E, Luft FC, Falck JR, Dragun D, et al. Inhibition of 20-HETE synthesis and action protects the kidney from ischemia/reperfusion injury. Kidney International. 79: 57-65. PMID 20962739 DOI: 10.1038/Ki.2010.377 |
0.338 |
|
| 2011 |
Bukhari IA, Gauthier KM, Jagadeesh SG, Sangras B, Falck JR, Campbell WB. 14,15-Dihydroxy-eicosa-5(Z)-enoic acid selectively inhibits 14,15-epoxyeicosatrienoic acid-induced relaxations in bovine coronary arteries. The Journal of Pharmacology and Experimental Therapeutics. 336: 47-55. PMID 20881018 DOI: 10.1124/Jpet.110.169797 |
0.395 |
|
| 2010 |
Tunctan B, Korkmaz B, Cuez T, Buharalioglu CK, Sahan-Firat S, Falck J, Malik KU. Contribution of Vasoactive Eicosanoids and Nitric Oxide Production to the Effect of Selective Cyclooxygenase-2 Inhibitor, NS-398, on Endotoxin-Induced Hypotension in Rats Basic & Clinical Pharmacology & Toxicology. 107: 877-882. PMID 22545970 DOI: 10.1111/J.1742-7843.2010.00589.X |
0.356 |
|
| 2010 |
Imig JD, Elmarakby A, Nithipatikom K, Wei S, Capdevila JH, Tuniki VR, Sangras B, Anjaiah S, Manthati VL, Sudarshan Reddy D, Falck JR. Development of epoxyeicosatrienoic acid analogs with in vivo anti-hypertensive actions. Frontiers in Physiology. 1: 157. PMID 21423396 DOI: 10.3389/Fphys.2010.00157 |
0.309 |
|
| 2010 |
Raffai G, Wang J, Roman RJ, Anjaiah S, Weinberg B, Falck JR, Lombard JH. Modulation by cytochrome P450-4A ω-hydroxylase enzymes of adrenergic vasoconstriction and response to reduced PO₂ in mesenteric resistance arteries of Dahl salt-sensitive rats. Microcirculation (New York, N.Y. : 1994). 17: 525-35. PMID 21040118 DOI: 10.1111/J.1549-8719.2010.00053.X |
0.309 |
|
| 2010 |
Higashimori H, Blanco VM, Tuniki VR, Falck JR, Filosa JA. Role of epoxyeicosatrienoic acids as autocrine metabolites in glutamate-mediated K+ signaling in perivascular astrocytes. American Journal of Physiology. Cell Physiology. 299: C1068-78. PMID 20844244 DOI: 10.1152/Ajpcell.00225.2010 |
0.301 |
|
| 2010 |
Sodhi K, Wu CC, Cheng J, Gotlinger K, Inoue K, Goli M, Falck JR, Abraham NG, Schwartzman ML. CYP4A2-induced hypertension is 20-hydroxyeicosatetraenoic acid- and angiotensin II-dependent. Hypertension. 56: 871-8. PMID 20837888 DOI: 10.1161/Hypertensionaha.110.154559 |
0.323 |
|
| 2010 |
Nithipatikom K, Brody DM, Tang AT, Manthati VL, Falck JR, Williams CL, Campbell WB. Inhibition of carcinoma cell motility by epoxyeicosatrienoic acid (EET) antagonists. Cancer Science. 101: 2629-36. PMID 20804500 DOI: 10.1111/J.1349-7006.2010.01713.X |
0.355 |
|
| 2010 |
Sun P, Lin DH, Yue P, Jiang H, Gotlinger KH, Schwartzman ML, Falck JR, Goli M, Wang WH. High potassium intake enhances the inhibitory effect of 11,12-EET on ENaC. Journal of the American Society of Nephrology : Jasn. 21: 1667-77. PMID 20595684 DOI: 10.1681/Asn.2009111110 |
0.353 |
|
| 2010 |
Lee CR, Imig JD, Edin ML, Foley J, DeGraff LM, Bradbury JA, Graves JP, Lih FB, Clark J, Myers P, Perrow AL, Lepp AN, Kannon MA, Ronnekleiv OK, Alkayed NJ, ... Falck JR, et al. Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 3770-81. PMID 20495177 DOI: 10.1096/Fj.10-160119 |
0.307 |
|
| 2010 |
Ma J, Zhang L, Li S, Liu S, Ma C, Li W, Falck JR, Manthati VL, Reddy DS, Medhora M, Jacobs ER, Zhu D. 8,9-Epoxyeicosatrienoic acid analog protects pulmonary artery smooth muscle cells from apoptosis via ROCK pathway. Experimental Cell Research. 316: 2340-53. PMID 20493836 DOI: 10.1016/J.Yexcr.2010.05.013 |
0.344 |
|
| 2010 |
Kim DH, Vanella L, Inoue K, Burgess A, Gotlinger K, Manthati VL, Koduru SR, Zeldin DC, Falck JR, Schwartzman ML, Abraham NG. Epoxyeicosatrienoic acid agonist regulates human mesenchymal stem cell-derived adipocytes through activation of HO-1-pAKT signaling and a decrease in PPARγ. Stem Cells and Development. 19: 1863-73. PMID 20412023 DOI: 10.1089/Scd.2010.0098 |
0.368 |
|
| 2010 |
Bodiga S, Gruenloh SK, Gao Y, Manthati VL, Dubasi N, Falck JR, Medhora M, Jacobs ER. 20-HETE-induced nitric oxide production in pulmonary artery endothelial cells is mediated by NADPH oxidase, H2O2, and PI3-kinase/Akt. American Journal of Physiology. Lung Cellular and Molecular Physiology. 298: L564-74. PMID 20061439 DOI: 10.1152/Ajplung.00298.2009 |
0.309 |
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| 2010 |
Certíková Chábová V, Walkowska A, Kompanowska-Jezierska E, Sadowski J, Kujal P, Vernerová Z, Vanourková Z, Kopkan L, Kramer HJ, Falck JR, Imig JD, Hammock BD, Vanecková I, Cervenka L. Combined inhibition of 20-hydroxyeicosatetraenoic acid formation and of epoxyeicosatrienoic acids degradation attenuates hypertension and hypertension-induced end-organ damage in Ren-2 transgenic rats. Clinical Science (London, England : 1979). 118: 617-32. PMID 20050826 DOI: 10.1042/Cs20090459 |
0.359 |
|
| 2010 |
Kopf PG, Zhang DX, Gauthier KM, Nithipatikom K, Yi XY, Falck JR, Campbell WB. Adrenic acid metabolites as endogenous endothelium-derived and zona glomerulosa-derived hyperpolarizing factors. Hypertension. 55: 547-54. PMID 20038752 DOI: 10.1161/Hypertensionaha.109.144147 |
0.407 |
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| 2010 |
Walkowska A, Skaroupková P, Husková Z, Vanourková Z, Chábová VC, Tesar V, Kramer HJ, Falck JR, Imig JD, Kompanowska-Jezierska E, Sadowski J, Cervenka L. Intrarenal cytochrome P-450 metabolites of arachidonic acid in the regulation of the nonclipped kidney function in two-kidney, one-clip Goldblatt hypertensive rats. Journal of Hypertension. 28: 582-93. PMID 19940786 DOI: 10.1097/Hjh.0B013E328334Dfd4 |
0.373 |
|
| 2010 |
Cheng J, Wu CC, Gotlinger KH, Zhang F, Falck JR, Narsimhaswamy D, Schwartzman ML. 20-hydroxy-5,8,11,14-eicosatetraenoic acid mediates endothelial dysfunction via IkappaB kinase-dependent endothelial nitric-oxide synthase uncoupling. The Journal of Pharmacology and Experimental Therapeutics. 332: 57-65. PMID 19841472 DOI: 10.1124/Jpet.109.159863 |
0.33 |
|
| 2009 |
Cuez T, Korkmaz B, Buharalioglu CK, Sahan-Firat S, Falck J, Malik KU, Tunctan B. A synthetic analogue of 20-HETE, 5,14-HEDGE, reverses endotoxin-induced hypotension via increased 20-HETE levels associated with decreased iNOS protein expression and vasodilator prostanoid production in rats Basic & Clinical Pharmacology & Toxicology. 106: 378-388. PMID 20002062 DOI: 10.1111/J.1742-7843.2009.00501.X |
0.336 |
|
| 2009 |
Liclican EL, Doumad AB, Wang J, Li J, Falck JR, Stier CT, Carroll MA. Inhibition of the adenosine2A receptor-epoxyeicosatrienoic acid pathway renders Dahl salt-resistant rats hypertensive. Hypertension. 54: 1284-90. PMID 19822802 DOI: 10.1161/Hypertensionaha.108.123570 |
0.319 |
|
| 2009 |
Chen Y, Falck JR, Tuniki VR, Campbell WB. 20-125Iodo-14,15-epoxyeicosa-5(Z)-enoic acid: a high-affinity radioligand used to characterize the epoxyeicosatrienoic acid antagonist binding site. The Journal of Pharmacology and Experimental Therapeutics. 331: 1137-45. PMID 19762546 DOI: 10.1124/Jpet.109.157818 |
0.344 |
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| 2009 |
Kunert MP, Friesma J, Falck JR, Lombard JH. CYP450 4A inhibition attenuates O2 induced arteriolar constriction in chronic but not acute Goldblatt hypertension. Microvascular Research. 78: 442-6. PMID 19761780 DOI: 10.1016/J.Mvr.2009.09.002 |
0.314 |
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| 2009 |
Chawengsub Y, Gauthier KM, Nithipatikom K, Hammock BD, Falck JR, Narsimhaswamy D, Campbell WB. Identification of 13-hydroxy-14,15-epoxyeicosatrienoic acid as an acid-stable endothelium-derived hyperpolarizing factor in rabbit arteries. The Journal of Biological Chemistry. 284: 31280-90. PMID 19737933 DOI: 10.1074/Jbc.M109.025627 |
0.383 |
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| 2009 |
Sodhi K, Inoue K, Gotlinger KH, Canestraro M, Vanella L, Kim DH, Manthati VL, Koduru SR, Falck JR, Schwartzman ML, Abraham NG. Epoxyeicosatrienoic acid agonist rescues the metabolic syndrome phenotype of HO-2-null mice. The Journal of Pharmacology and Experimental Therapeutics. 331: 906-16. PMID 19717790 DOI: 10.1124/Jpet.109.157545 |
0.302 |
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| 2009 |
Inoue K, Sodhi K, Puri N, Gotlinger KH, Cao J, Rezzani R, Falck JR, Abraham NG, Laniado-Schwartzman M. Endothelial-specific CYP4A2 overexpression leads to renal injury and hypertension via increased production of 20-HETE American Journal of Physiology-Renal Physiology. 297. PMID 19675180 DOI: 10.1152/Ajprenal.00364.2009 |
0.361 |
|
| 2009 |
Falck JR, Kodela R, Manne R, Atcha KR, Puli N, Dubasi N, Manthati VL, Capdevila JH, Yi XY, Goldman DH, Morisseau C, Hammock BD, Campbell WB. 14,15-Epoxyeicosa-5,8,11-trienoic acid (14,15-EET) surrogates containing epoxide bioisosteres: influence upon vascular relaxation and soluble epoxide hydrolase inhibition. Journal of Medicinal Chemistry. 52: 5069-75. PMID 19653681 DOI: 10.1021/Jm900634W |
0.371 |
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| 2009 |
Akbulut T, Regner KR, Roman RJ, Avner ED, Falck JR, Park F. 20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism. American Journal of Physiology. Renal Physiology. 297: F662-70. PMID 19570883 DOI: 10.1152/Ajprenal.00146.2009 |
0.315 |
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| 2009 |
Marowsky A, Burgener J, Falck JR, Fritschy JM, Arand M. Distribution of soluble and microsomal epoxide hydrolase in the mouse brain and its contribution to cerebral epoxyeicosatrienoic acid metabolism. Neuroscience. 163: 646-61. PMID 19540314 DOI: 10.1016/J.Neuroscience.2009.06.033 |
0.301 |
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| 2009 |
Sharma M, McCarthy ET, Reddy DS, Patel PK, Savin VJ, Medhora M, Falck JR. 8,9-Epoxyeicosatrienoic acid protects the glomerular filtration barrier. Prostaglandins & Other Lipid Mediators. 89: 43-51. PMID 19480064 DOI: 10.1016/J.Prostaglandins.2009.04.004 |
0.369 |
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| 2009 |
Gross GJ, Gauthier KM, Moore J, Campbell WB, Falck JR, Nithipatikom K. Evidence for role of epoxyeicosatrienoic acids in mediating ischemic preconditioning and postconditioning in dog. American Journal of Physiology. Heart and Circulatory Physiology. 297: H47-52. PMID 19448143 DOI: 10.1152/Ajpheart.01084.2008 |
0.358 |
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| 2009 |
Ellis A, Goto K, Chaston DJ, Brackenbury TD, Meaney KR, Falck JR, Wojcikiewicz RJ, Hill CE. Enalapril treatment alters the contribution of epoxyeicosatrienoic acids but not gap junctions to endothelium-derived hyperpolarizing factor activity in mesenteric arteries of spontaneously hypertensive rats. The Journal of Pharmacology and Experimental Therapeutics. 330: 413-22. PMID 19411610 DOI: 10.1124/Jpet.109.152116 |
0.331 |
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| 2009 |
Bodiga S, Zhang R, Jacobs DE, Larsen BT, Tampo A, Manthati VL, Kwok WM, Zeldin DC, Falck JR, Gutterman DD, Jacobs ER, Medhora MM. Protective actions of epoxyeicosatrienoic acid: dual targeting of cardiovascular PI3K and KATP channels. Journal of Molecular and Cellular Cardiology. 46: 978-88. PMID 19336274 DOI: 10.1016/J.Yjmcc.2009.01.009 |
0.321 |
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| 2009 |
Katragadda D, Batchu SN, Cho WJ, Chaudhary KR, Falck JR, Seubert JM. Epoxyeicosatrienoic acids limit damage to mitochondrial function following stress in cardiac cells. Journal of Molecular and Cellular Cardiology. 46: 867-75. PMID 19285984 DOI: 10.1016/J.Yjmcc.2009.02.028 |
0.334 |
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| 2009 |
Dhanasekaran A, Bodiga S, Gruenloh S, Gao Y, Dunn L, Falck JR, Buonaccorsi JN, Medhora M, Jacobs ER. 20-HETE increases survival and decreases apoptosis in pulmonary arteries and pulmonary artery endothelial cells. American Journal of Physiology. Heart and Circulatory Physiology. 296: H777-86. PMID 19136601 DOI: 10.1152/Ajpheart.01087.2008 |
0.332 |
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| 2009 |
Regner KR, Zuk A, Van Why SK, Shames BD, Ryan RP, Falck JR, Manthati VL, McMullen ME, Ledbetter SR, Roman RJ. Protective effect of 20-HETE analogues in experimental renal ischemia reperfusion injury Kidney International. 75: 511-517. PMID 19052533 DOI: 10.1038/Ki.2008.600 |
0.309 |
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| 2009 |
Baati R, Mioskowski C, Kashinath D, Kodepelly S, Lu B, Falck JR. Stereoselective synthesis of methyl (Z)-α-methoxyacrylates via two-carbon homologation of aldehydes Tetrahedron Letters. 50: 402-405. DOI: 10.1016/J.Tetlet.2008.11.027 |
0.303 |
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| 2008 |
Dunn KM, Renic M, Flasch AK, Harder DR, Falck J, Roman RJ. Elevated production of 20-HETE in the cerebral vasculature contributes to severity of ischemic stroke and oxidative stress in spontaneously hypertensive rats. American Journal of Physiology. Heart and Circulatory Physiology. 295: H2455-65. PMID 18952718 DOI: 10.1152/Ajpheart.00512.2008 |
0.3 |
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| 2008 |
Liclican EL, McGiff JC, Falck JR, Carroll MA. Failure to upregulate the adenosine2A receptor-epoxyeicosatrienoic acid pathway contributes to the development of hypertension in Dahl salt-sensitive rats. American Journal of Physiology. Renal Physiology. 295: F1696-704. PMID 18829737 DOI: 10.1152/Ajprenal.90502.2008 |
0.358 |
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| 2008 |
Nayeem MA, Poloyac SM, Falck JR, Zeldin DC, Ledent C, Ponnoth DS, Ansari HR, Mustafa SJ. Role of CYP epoxygenases in A2A AR-mediated relaxation using A2A AR-null and wild-type mice. American Journal of Physiology. Heart and Circulatory Physiology. 295: H2068-78. PMID 18805895 DOI: 10.1152/Ajpheart.01333.2007 |
0.313 |
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| 2008 |
Webler AC, Michaelis UR, Popp R, Barbosa-Sicard E, Murugan A, Falck JR, Fisslthaler B, Fleming I. Epoxyeicosatrienoic acids are part of the VEGF-activated signaling cascade leading to angiogenesis. American Journal of Physiology. Cell Physiology. 295: C1292-301. PMID 18787075 DOI: 10.1152/Ajpcell.00230.2008 |
0.308 |
|
| 2008 |
Chen JK, Chen J, Imig JD, Wei S, Hachey DL, Guthi JS, Falck JR, Capdevila JH, Harris RC. Identification of novel endogenous cytochrome p450 arachidonate metabolites with high affinity for cannabinoid receptors. The Journal of Biological Chemistry. 283: 24514-24. PMID 18606824 DOI: 10.1074/Jbc.M709873200 |
0.386 |
|
| 2008 |
Guo AM, Sheng J, Scicli GM, Arbab AS, Lehman NL, Edwards PA, Falck JR, Roman RJ, Scicli AG. Expression of CYP4A1 in U251 human glioma cell induces hyperproliferative phenotype in vitro and rapidly growing tumors in vivo. The Journal of Pharmacology and Experimental Therapeutics. 327: 10-9. PMID 18591218 DOI: 10.1124/Jpet.108.140889 |
0.321 |
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| 2008 |
Li J, Carroll MA, Chander PN, Falck JR, Sangras B, Stier CT. Soluble epoxide hydrolase inhibitor, AUDA, prevents early salt-sensitive hypertension. Frontiers in Bioscience : a Journal and Virtual Library. 13: 3480-7. PMID 18508449 DOI: 10.2741/2942 |
0.336 |
|
| 2008 |
Liu X, Li C, Falck JR, Roman RJ, Harder DR, Koehler RC. Interaction of nitric oxide, 20-HETE, and EETs during functional hyperemia in whisker barrel cortex. American Journal of Physiology. Heart and Circulatory Physiology. 295: H619-31. PMID 18502903 DOI: 10.1152/Ajpheart.01211.2007 |
0.349 |
|
| 2008 |
Jain K, Siddam A, Marathi A, Roy U, Falck JR, Balazy M. The mechanism of oleic acid nitration by •NO2 Free Radical Biology and Medicine. 45: 269-283. PMID 18457679 DOI: 10.1016/J.Freeradbiomed.2008.04.015 |
0.373 |
|
| 2008 |
Jiang H, Zhu AG, Mamczur M, Morisseau C, Hammock BD, Falck JR, McGiff JC. Hydrolysis of cis- and trans-epoxyeicosatrienoic acids by rat red blood cells. The Journal of Pharmacology and Experimental Therapeutics. 326: 330-7. PMID 18445784 DOI: 10.1124/Jpet.107.134858 |
0.332 |
|
| 2008 |
Gross GJ, Gauthier KM, Moore J, Falck JR, Hammock BD, Campbell WB, Nithipatikom K. Effects of the selective EET antagonist, 14,15-EEZE, on cardioprotection produced by exogenous or endogenous EETs in the canine heart. American Journal of Physiology. Heart and Circulatory Physiology. 294: H2838-44. PMID 18441205 DOI: 10.1152/Ajpheart.00186.2008 |
0.337 |
|
| 2008 |
Wang Z, Wei Y, Falck JR, Atcha KR, Wang W. Arachidonic acid inhibits basolateral K channels in the cortical collecting duct via cytochrome P-450 epoxygenase-dependent metabolic pathways. American Journal of Physiology-Renal Physiology. 294. PMID 18417544 DOI: 10.1152/Ajprenal.00038.2008 |
0.33 |
|
| 2008 |
Berezan DJ, Dunn KMJ, Falck JR, Davidge ST. Aging increases cytochrome P450 4A modulation of α1-adrenergic vasoconstriction in mesenteric arteries Journal of Cardiovascular Pharmacology. 51: 327-330. PMID 18356699 DOI: 10.1097/Fjc.0B013E318160B415 |
0.314 |
|
| 2008 |
Michaelis UR, Xia N, Barbosa-Sicard E, Falck JR, Fleming I. Role of cytochrome P450 2C epoxygenases in hypoxia-induced cell migration and angiogenesis in retinal endothelial cells. Investigative Ophthalmology & Visual Science. 49: 1242-1247. PMID 18326754 DOI: 10.1167/Iovs.07-1087 |
0.311 |
|
| 2008 |
Tunctan B, Korkmaz B, Buharalioglu CK, Firat SS, Anjaiah S, Falck J, Roman RJ, Malik KU. A 20-hydroxyeicosatetraenoic acid agonist, N-[20-hydroxyeicosa-5(Z),14(Z)-dienoyl]glycine, opposes the fall in blood pressure and vascular reactivity in endotoxin-treated rats. Shock. 30: 329-335. PMID 18323740 DOI: 10.1097/Shk.0B013E31816471C6 |
0.343 |
|
| 2008 |
Medhora M, Chen Y, Gruenloh S, Harland D, Bodiga S, Zielonka J, Gebremedhin D, Gao Y, Falck JR, Anjaiah S, Jacobs ER. 20-HETE increases superoxide production and activates NAPDH oxidase in pulmonary artery endothelial cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 294: L902-11. PMID 18296498 DOI: 10.1152/Ajplung.00278.2007 |
0.333 |
|
| 2008 |
Imig JD, Dimitropoulou C, Reddy DS, White RE, Falck JR. Afferent arteriolar dilation to 11, 12-EET analogs involves PP2A activity and Ca2+-activated K+ Channels. Microcirculation (New York, N.Y. : 1994). 15: 137-50. PMID 18260004 DOI: 10.1080/10739680701456960 |
0.34 |
|
| 2008 |
Gauthier KM, Chawengsub Y, Goldman DH, Conrow RE, Anjaiah S, Falck JR, Campbell WB. 11(R),12(S),15(S)-trihydroxyeicosa-5(Z),8(Z),13(E)-trienoic acid: an endothelium-derived 15-lipoxygenase metabolite that relaxes rabbit aorta. American Journal of Physiology. Heart and Circulatory Physiology. 294: H1467-72. PMID 18203841 DOI: 10.1152/Ajpheart.01052.2007 |
0.354 |
|
| 2008 |
Chawengsub Y, Aggarwal NT, Nithipatikom K, Gauthier KM, Anjaiah S, Hammock BD, Falck JR, Campbell WB. Identification of 15-hydroxy-11,12-epoxyeicosatrienoic acid as a vasoactive 15-lipoxygenase metabolite in rabbit aorta. American Journal of Physiology. Heart and Circulatory Physiology. 294: H1348-56. PMID 18192225 DOI: 10.1152/Ajpheart.01326.2007 |
0.359 |
|
| 2008 |
Yang W, Tuniki VR, Anjaiah S, Falck JR, Hillard CJ, Campbell WB. Characterization of epoxyeicosatrienoic acid binding site in U937 membranes using a novel radiolabeled agonist, 20-125i-14,15-epoxyeicosa-8(Z)-enoic acid. The Journal of Pharmacology and Experimental Therapeutics. 324: 1019-27. PMID 18171909 DOI: 10.1124/Jpet.107.129577 |
0.331 |
|
| 2008 |
Cheng J, Ou JS, Singh H, Falck JR, Narsimhaswamy D, Pritchard KA, Schwartzman ML. 20-hydroxyeicosatetraenoic acid causes endothelial dysfunction via eNOS uncoupling. American Journal of Physiology. Heart and Circulatory Physiology. 294: H1018-26. PMID 18156192 DOI: 10.1152/Ajpheart.01172.2007 |
0.372 |
|
| 2008 |
Li de R, Murugan A, Falck JR. Enantioselective, organocatalytic oxy-michael addition to gamma/delta-hydroxy-alpha,beta-enones: boronate-amine complexes as chiral hydroxide synthons. Journal of the American Chemical Society. 130: 46-8. PMID 18076175 DOI: 10.1021/Ja076802C |
0.312 |
|
| 2008 |
Dhanasekaran A, Gruenloh SK, Buonaccorsi JN, Zhang R, Gross GJ, Falck JR, Patel PK, Jacobs ER, Medhora M. Multiple antiapoptotic targets of the PI3K/Akt survival pathway are activated by epoxyeicosatrienoic acids to protect cardiomyocytes from hypoxia/anoxia. American Journal of Physiology. Heart and Circulatory Physiology. 294: H724-35. PMID 18055514 DOI: 10.1152/Ajpheart.00979.2007 |
0.305 |
|
| 2008 |
Larsen BT, Gutterman DD, Sato A, Toyama K, Campbell WB, Zeldin DC, Manthati VL, Falck JR, Miura H. Hydrogen peroxide inhibits cytochrome p450 epoxygenases: interaction between two endothelium-derived hyperpolarizing factors. Circulation Research. 102: 59-67. PMID 17975109 DOI: 10.1161/Circresaha.107.159129 |
0.377 |
|
| 2008 |
Ishizuka T, Cheng J, Singh H, Vitto MD, Manthati VL, Falck JR, Laniado-Schwartzman M. 20-Hydroxyeicosatetraenoic acid stimulates nuclear factor-kappaB activation and the production of inflammatory cytokines in human endothelial cells. The Journal of Pharmacology and Experimental Therapeutics. 324: 103-10. PMID 17947496 DOI: 10.1124/Jpet.107.130336 |
0.315 |
|
| 2008 |
Shi Y, Liu X, Gebremedhin D, Falck JR, Harder DR, Koehler RC. Interaction of mechanisms involving epoxyeicosatrienoic acids, adenosine receptors, and metabotropic glutamate receptors in neurovascular coupling in rat whisker barrel cortex. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 28: 111-25. PMID 17519974 DOI: 10.1038/Sj.Jcbfm.9600511 |
0.3 |
|
| 2007 |
Fleming I, Rueben A, Popp R, Fisslthaler B, Schrodt S, Sander A, Haendeler J, Falck JR, Morisseau C, Hammock BD, Busse R. Epoxyeicosatrienoic acids regulate Trp channel dependent Ca2+ signaling and hyperpolarization in endothelial cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 2612-8. PMID 17872452 DOI: 10.1161/Atvbaha.107.152074 |
0.343 |
|
| 2007 |
Certíková Chábová V, Kramer HJ, Vanecková I, Thumová M, Skaroupková P, Tesar V, Falck JR, Imig JD, Cervenka L. The roles of intrarenal 20-hydroxyeicosatetraenoic and epoxyeicosatrienoic acids in the regulation of renal function in hypertensive Ren-2 transgenic rats. Kidney & Blood Pressure Research. 30: 335-46. PMID 17785988 DOI: 10.1159/000107710 |
0.36 |
|
| 2007 |
Choi JH, Williams J, Cho J, Falck JR, Shears SB. Purification, sequencing, and molecular identification of a mammalian PP-InsP5 kinase that is activated when cells are exposed to hyperosmotic stress. The Journal of Biological Chemistry. 282: 30763-75. PMID 17702752 DOI: 10.1074/Jbc.M704655200 |
0.307 |
|
| 2007 |
Capdevila JH, Falck JR, Imig JD. Roles of the cytochrome P450 arachidonic acid monooxygenases in the control of systemic blood pressure and experimental hypertension. Kidney International. 72: 683-9. PMID 17597703 DOI: 10.1038/Sj.Ki.5002394 |
0.33 |
|
| 2007 |
Jiang H, Zhu AG, Mamczur M, Falck JR, Lerea KM, McGiff JC. Stimulation of rat erythrocyte P2X7 receptor induces the release of epoxyeicosatrienoic acids. British Journal of Pharmacology. 151: 1033-40. PMID 17558440 DOI: 10.1038/Sj.Bjp.0707311 |
0.337 |
|
| 2007 |
Williams JM, Sharma M, Anjaiahh S, Falck JR, Roman RJ. Role of endogenous CYP450 metabolites of arachidonic acid in maintaining the glomerular protein permeability barrier American Journal of Physiology-Renal Physiology. 293. PMID 17507602 DOI: 10.1152/Ajprenal.00131.2007 |
0.389 |
|
| 2007 |
Zhang DX, Gauthier KM, Falck JR, Siddam A, Campbell WB. Steroid-producing cells regulate arterial tone of adrenal cortical arteries. Endocrinology. 148: 3569-76. PMID 17446179 DOI: 10.1210/En.2007-0169 |
0.312 |
|
| 2007 |
Huang H, Morisseau C, Wang J, Yang T, Falck JR, Hammock BD, Wang MH. Increasing or stabilizing renal epoxyeicosatrienoic acid production attenuates abnormal renal function and hypertension in obese rats. American Journal of Physiology. Renal Physiology. 293: F342-9. PMID 17442729 DOI: 10.1152/Ajprenal.00004.2007 |
0.328 |
|
| 2007 |
Zhang W, Koerner IP, Noppens R, Grafe M, Tsai HJ, Morisseau C, Luria A, Hammock BD, Falck JR, Alkayed NJ. Soluble epoxide hydrolase: a novel therapeutic target in stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 27: 1931-40. PMID 17440491 DOI: 10.1038/Sj.Jcbfm.9600494 |
0.316 |
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| 2007 |
Ng VY, Huang Y, Reddy LM, Falck JR, Lin ET, Kroetz DL. Cytochrome P450 eicosanoids are activators of peroxisome proliferator-activated receptor alpha. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 1126-34. PMID 17431031 DOI: 10.1124/Dmd.106.013839 |
0.385 |
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| 2007 |
Pozzi A, Ibanez MR, Gatica AE, Yang S, Wei S, Mei S, Falck JR, Capdevila JH. Peroxisomal proliferator-activated receptor-alpha-dependent inhibition of endothelial cell proliferation and tumorigenesis. The Journal of Biological Chemistry. 282: 17685-95. PMID 17405874 DOI: 10.1074/Jbc.M701429200 |
0.322 |
|
| 2007 |
Yang W, Holmes BB, Gopal VR, Kishore RV, Sangras B, Yi XY, Falck JR, Campbell WB. Characterization of 14,15-epoxyeicosatrienoyl-sulfonamides as 14,15-epoxyeicosatrienoic acid agonists: use for studies of metabolism and ligand binding. The Journal of Pharmacology and Experimental Therapeutics. 321: 1023-31. PMID 17327488 DOI: 10.1124/Jpet.107.119651 |
0.349 |
|
| 2007 |
Falck JR, Reddy LM, Byun K, Campbell WB, Yi XY. Epoxygenase eicosanoids: synthesis of tetrahydrofuran-diol metabolites and their vasoactivity. Bioorganic & Medicinal Chemistry Letters. 17: 2634-8. PMID 17293113 DOI: 10.1016/J.Bmcl.2007.01.096 |
0.33 |
|
| 2007 |
Chen J, Chen JK, Falck JR, Guthi JS, Anjaiah S, Capdevila JH, Harris RC. Mitogenic activity and signaling mechanism of 2-(14,15- epoxyeicosatrienoyl)glycerol, a novel cytochrome p450 arachidonate metabolite. Molecular and Cellular Biology. 27: 3023-34. PMID 17283047 DOI: 10.1128/Mcb.01482-06 |
0.327 |
|
| 2007 |
Dimitropoulou C, West L, Field MB, White RE, Reddy LM, Falck JR, Imig JD. Protein phosphatase 2A and Ca2+-activated K+ channels contribute to 11,12-epoxyeicosatrienoic acid analog mediated mesenteric arterial relaxation. Prostaglandins & Other Lipid Mediators. 83: 50-61. PMID 17259072 DOI: 10.1016/J.Prostaglandins.2006.09.008 |
0.339 |
|
| 2007 |
Gross GJ, Hsu A, Falck JR, Nithipatikom K. Mechanisms by which epoxyeicosatrienoic acids (EETs) elicit cardioprotection in rat hearts. Journal of Molecular and Cellular Cardiology. 42: 687-91. PMID 17217955 DOI: 10.1016/J.Yjmcc.2006.11.020 |
0.307 |
|
| 2007 |
Guo AM, Arbab AS, Falck JR, Chen P, Edwards PA, Roman RJ, Scicli AG. Activation of vascular endothelial growth factor through reactive oxygen species mediates 20-hydroxyeicosatetraenoic acid-induced endothelial cell proliferation. The Journal of Pharmacology and Experimental Therapeutics. 321: 18-27. PMID 17210799 DOI: 10.1124/Jpet.106.115360 |
0.363 |
|
| 2007 |
Yi XY, Gauthier KM, Cui L, Nithipatikom K, Falck JR, Campbell WB. Metabolism of adrenic acid to vasodilatory 1alpha,1beta-dihomo-epoxyeicosatrienoic acids by bovine coronary arteries. American Journal of Physiology. Heart and Circulatory Physiology. 292: H2265-74. PMID 17209008 DOI: 10.1152/Ajpheart.00947.2006 |
0.377 |
|
| 2007 |
Campbell WB, Falck JR. Arachidonic acid metabolites as endothelium-derived hyperpolarizing factors. Hypertension (Dallas, Tex. : 1979). 49: 590-6. PMID 17200437 DOI: 10.1161/01.Hyp.0000255173.50317.Fc |
0.388 |
|
| 2007 |
Fang X, Dillon JS, Hu S, Harmon SD, Yao J, Anjaiah S, Falck JR, Spector AA. 20-carboxy-arachidonic acid is a dual activator of peroxisome proliferator-activated receptors alpha and gamma. Prostaglandins & Other Lipid Mediators. 82: 175-84. PMID 17164145 DOI: 10.1016/J.Prostaglandins.2006.05.002 |
0.376 |
|
| 2007 |
Sacerdoti D, Colombrita C, Di Pascoli M, Schwartzman ML, Bolognesi M, Falck JR, Gatta A, Abraham NG. 11,12-epoxyeicosatrienoic acid stimulates heme-oxygenase-1 in endothelial cells. Prostaglandins & Other Lipid Mediators. 82: 155-61. PMID 17164143 DOI: 10.1016/J.Prostaglandins.2006.07.001 |
0.32 |
|
| 2007 |
Medhora M, Dhanasekaran A, Gruenloh SK, Dunn LK, Gabrilovich M, Falck JR, Harder DR, Jacobs ER, Pratt PF. Emerging mechanisms for growth and protection of the vasculature by cytochrome P450-derived products of arachidonic acid and other eicosanoids. Prostaglandins & Other Lipid Mediators. 82: 19-29. PMID 17164129 DOI: 10.1016/J.Prostaglandins.2006.05.025 |
0.382 |
|
| 2007 |
Hagedorn KA, Cooke CL, Falck JR, Mitchell BF, Davidge ST. Regulation of vascular tone during pregnancy: A novel role for the pregnane X receptor Hypertension. 49: 328-333. PMID 17159084 DOI: 10.1161/01.Hyp.0000253478.51950.27 |
0.322 |
|
| 2007 |
Marvar PJ, Falck JR, Boegehold MA. High dietary salt reduces the contribution of 20-HETE to arteriolar oxygen responsiveness in skeletal muscle. American Journal of Physiology. Heart and Circulatory Physiology. 292: H1507-15. PMID 17114243 DOI: 10.1152/Ajpheart.00754.2006 |
0.307 |
|
| 2007 |
Drouin A, Thorin-Trescases N, Hamel E, Falck JR, Thorin E. Endothelial nitric oxide synthase activation leads to dilatory H2O2 production in mouse cerebral arteries. Cardiovascular Research. 73: 73-81. PMID 17113574 DOI: 10.1016/J.Cardiores.2006.10.005 |
0.308 |
|
| 2006 |
Falck JR, Anjaiah S, Tuniki VR, Gopal VR, Capdevila JH. Convenient syntheses of [20,20,20-H(3)]-arachidonic acid and [20,20-H(2)]-20-hydroxyeicosatetraenoic acid. Journal of Labelled Compounds & Radiopharmaceuticals. 49: 245-252. PMID 16951707 DOI: 10.1002/Jlcr.1039 |
0.343 |
|
| 2006 |
Seubert JM, Sinal CJ, Graves J, DeGraff LM, Bradbury JA, Lee CR, Goralski K, Carey MA, Luria A, Newman JW, Hammock BD, Falck JR, Roberts H, Rockman HA, Murphy E, et al. Role of soluble epoxide hydrolase in postischemic recovery of heart contractile function. Circulation Research. 99: 442-50. PMID 16857962 DOI: 10.1161/01.Res.0000237390.92932.37 |
0.318 |
|
| 2006 |
Harmon SD, Fang X, Kaduce TL, Hu S, Raj Gopal V, Falck JR, Spector AA. Oxygenation of omega-3 fatty acids by human cytochrome P450 4F3B: effect on 20-hydroxyeicosatetraenoic acid production. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 75: 169-77. PMID 16820285 DOI: 10.1016/J.Plefa.2006.05.005 |
0.391 |
|
| 2006 |
Fang X, Faraci FM, Kaduce TL, Harmon S, Modrick ML, Hu S, Moore SA, Falck JR, Weintraub NL, Spector AA. 20-Hydroxyeicosatetraenoic acid is a potent dilator of mouse basilar artery: role of cyclooxygenase. American Journal of Physiology. Heart and Circulatory Physiology. 291: H2301-7. PMID 16782846 DOI: 10.1152/Ajpheart.00349.2006 |
0.37 |
|
| 2006 |
Ye D, Zhou W, Lu T, Jagadeesh SG, Falck JR, Lee HC. Mechanism of rat mesenteric arterial KATP channel activation by 14,15-epoxyeicosatrienoic acid. American Journal of Physiology. Heart and Circulatory Physiology. 290: H1326-36. PMID 16537788 DOI: 10.1152/Ajpheart.00318.2005 |
0.332 |
|
| 2006 |
Wei S, Brittin JJ, Falck JR, Anjaiah S, Nithipatikom K, Cui L, Campbell WB, Capdevila JH. Chiral resolution of the epoxyeicosatrienoic acids, arachidonic acid epoxygenase metabolites. Analytical Biochemistry. 352: 129-34. PMID 16480681 DOI: 10.1016/J.Ab.2006.01.005 |
0.373 |
|
| 2006 |
Carroll MA, Doumad AB, Li J, Cheng MK, Falck JR, McGiff JC. Adenosine2A receptor vasodilation of rat preglomerular microvessels is mediated by EETs that activate the cAMP/PKA pathway. American Journal of Physiology. Renal Physiology. 291: F155-61. PMID 16478979 DOI: 10.1152/Ajprenal.00231.2005 |
0.317 |
|
| 2006 |
Nithipatikom K, Moore JM, Isbell MA, Falck JR, Gross GJ. Epoxyeicosatrienoic acids in cardioprotection: ischemic versus reperfusion injury. American Journal of Physiology. Heart and Circulatory Physiology. 291: H537-42. PMID 16473964 DOI: 10.1152/Ajpheart.00071.2006 |
0.351 |
|
| 2006 |
McSherry IN, Sandow SL, Campbell WB, Falck JR, Hill MA, Dora KA. A role for heterocellular coupling and EETs in dilation of rat cremaster arteries. Microcirculation (New York, N.Y. : 1994). 13: 119-30. PMID 16459325 DOI: 10.1080/10739680500466400 |
0.304 |
|
| 2006 |
Jin L, Foss CE, Zhao X, Mills TM, Wang MH, McCluskey LP, Yaddanapud GS, Falck JR, Imig JD, Webb RC. Cytochrome P450 epoxygenases provide a novel mechanism for penile erection. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 539-41. PMID 16415108 DOI: 10.1096/Fj.05-4341Fje |
0.364 |
|
| 2006 |
Guo M, Roman RJ, Fenstermacher JD, Brown SL, Falck JR, Arbab AS, Edwards PA, Scicli AG. 9L gliosarcoma cell proliferation and tumor growth in rats are suppressed by N-hydroxy-N'-(4-butyl-2-methylphenol) formamidine (HET0016), a selective inhibitor of CYP4A. The Journal of Pharmacology and Experimental Therapeutics. 317: 97-108. PMID 16352703 DOI: 10.1124/Jpet.105.097782 |
0.325 |
|
| 2006 |
Larsen BT, Miura H, Hatoum OA, Campbell WB, Hammock BD, Zeldin DC, Falck JR, Gutterman DD. Epoxyeicosatrienoic and dihydroxyeicosatrienoic acids dilate human coronary arterioles via BK(Ca) channels: implications for soluble epoxide hydrolase inhibition. American Journal of Physiology. Heart and Circulatory Physiology. 290: H491-9. PMID 16258029 DOI: 10.1152/Ajpheart.00927.2005 |
0.338 |
|
| 2006 |
Nithipatikom K, Endsley MP, Moore JM, Isbell MA, Falck JR, Campbell WB, Gross GJ. Effects of selective inhibition of cytochrome P-450 omega-hydroxylases and ischemic preconditioning in myocardial protection. American Journal of Physiology. Heart and Circulatory Physiology. 290: H500-5. PMID 16214838 DOI: 10.1152/Ajpheart.00918.2005 |
0.306 |
|
| 2006 |
Du L, Yermalitsky V, Hachey DL, Jagadeesh SG, Falck JR, Keeney DS. A biosynthetic pathway generating 12-hydroxy-5,8,14-eicosatrienoic acid from arachidonic acid is active in mouse skin microsomes. The Journal of Pharmacology and Experimental Therapeutics. 316: 371-9. PMID 16169934 DOI: 10.1124/Jpet.105.093922 |
0.377 |
|
| 2006 |
Campbell WB, Holmes BB, Falck JR, Capdevila JH, Gauthier KM. Regulation of potassium channels in coronary smooth muscle by adenoviral expression of cytochrome P-450 epoxygenase. American Journal of Physiology. Heart and Circulatory Physiology. 290: H64-71. PMID 16143653 DOI: 10.1152/Ajpheart.00516.2005 |
0.335 |
|
| 2006 |
Fang X, Hu S, Xu B, Snyder GD, Harmon S, Yao J, Liu Y, Sangras B, Falck JR, Weintraub NL, Spector AA. 14,15-Dihydroxyeicosatrienoic acid activates peroxisome proliferator-activated receptor-alpha. American Journal of Physiology. Heart and Circulatory Physiology. 290: H55-63. PMID 16113065 DOI: 10.1152/Ajpheart.00427.2005 |
0.372 |
|
| 2006 |
Tang X, Edwards EM, Holmes BB, Falck JR, Campbell WB. Role of phospholipase C and diacylglyceride lipase pathway in arachidonic acid release and acetylcholine-induced vascular relaxation in rabbit aorta. American Journal of Physiology. Heart and Circulatory Physiology. 290: H37-45. PMID 16024567 DOI: 10.1152/Ajpheart.00491.2005 |
0.347 |
|
| 2006 |
Michaelis UR, Fisslthaler B, Xia N, Barbosa-Sicard E, Falck JR, Fleming I, Busse R. Epoxyeicosatrienoic acids act as second messengers in VEGF-induced angiogenesis Vascular Pharmacology. 45. DOI: 10.1016/J.Vph.2006.08.309 |
0.327 |
|
| 2005 |
Michaelis UR, Fisslthaler B, Barbosa-Sicard E, Falck JR, Fleming I, Busse R. Cytochrome P450 epoxygenases 2C8 and 2C9 are implicated in hypoxia-induced endothelial cell migration and angiogenesis Journal of Cell Science. 118: 5489-5498. PMID 16291720 DOI: 10.1242/Jcs.02674 |
0.321 |
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| 2005 |
Wang H, Garvin JL, Falck JR, Ren Y, Sankey SS, Carretero OA. Glomerular cytochrome P-450 and cyclooxygenase metabolites regulate efferent arteriole resistance. Hypertension (Dallas, Tex. : 1979). 46: 1175-9. PMID 16230518 DOI: 10.1161/01.Hyp.0000187531.93389.63 |
0.394 |
|
| 2005 |
Guo M, Roman RJ, Falck JR, Edwards PA, Scicli AG. Human U251 glioma cell proliferation is suppressed by HET0016 [N-hydroxy-N'-(4-butyl-2-methylphenyl)formamidine], a selective inhibitor of CYP4A. The Journal of Pharmacology and Experimental Therapeutics. 315: 526-33. PMID 16081682 DOI: 10.1124/Jpet.105.088567 |
0.354 |
|
| 2005 |
Collins XH, Harmon SD, Kaduce TL, Berst KB, Fang X, Moore SA, Raju TV, Falck JR, Weintraub NL, Duester G, Plapp BV, Spector AA. Omega-oxidation of 20-hydroxyeicosatetraenoic acid (20-HETE) in cerebral microvascular smooth muscle and endothelium by alcohol dehydrogenase 4. The Journal of Biological Chemistry. 280: 33157-64. PMID 16081420 DOI: 10.1074/Jbc.M504055200 |
0.356 |
|
| 2005 |
Mezentsev A, Mastyugin V, Seta F, Ashkar S, Kemp R, Reddy DS, Falck JR, Dunn MW, Laniado-Schwartzman M. Transfection of cytochrome P4504B1 into the cornea increases angiogenic activity of the limbal vessels. The Journal of Pharmacology and Experimental Therapeutics. 315: 42-50. PMID 16009741 DOI: 10.1124/Jpet.105.088211 |
0.313 |
|
| 2005 |
Huang H, Zhou Y, Raju VT, Du J, Chang HH, Wang CY, Brands MW, Falck JR, Wang MH. Renal 20-HETE inhibition attenuates changes in renal hemodynamics induced by L-NAME treatment in pregnant rats. American Journal of Physiology. Renal Physiology. 289: F1116-22. PMID 15998843 DOI: 10.1152/Ajprenal.00149.2005 |
0.321 |
|
| 2005 |
Gross GJ, Falck JR, Gross ER, Isbell M, Moore J, Nithipatikom K. Cytochrome P450 and arachidonic acid metabolites: role in myocardial ischemia/reperfusion injury revisited. Cardiovascular Research. 68: 18-25. PMID 15993870 DOI: 10.1016/J.Cardiores.2005.06.007 |
0.366 |
|
| 2005 |
Parmentier JH, Lavrentyev EN, Falck JR, Capdevila JH, Malik KU. Evaluation of cytochrome P450 4 family as mediator of phospholipase D activation in aortic vascular smooth muscle cells. Life Sciences. 77: 1015-29. PMID 15964316 DOI: 10.1016/J.Lfs.2005.03.002 |
0.382 |
|
| 2005 |
Dunn LK, Gruenloh SK, Dunn BE, Reddy DS, Falck JR, Jacobs ER, Medhora M. Chick chorioallantoic membrane as an in vivo model to study vasoreactivity: characterization of development-dependent hyperemia induced by epoxyeicosatrienoic acids (EETs). The Anatomical Record. Part a, Discoveries in Molecular, Cellular, and Evolutionary Biology. 285: 771-80. PMID 15952186 DOI: 10.1002/Ar.A.20212 |
0.349 |
|
| 2005 |
Pozzi A, Macias-Perez I, Abair T, Wei S, Su Y, Zent R, Falck JR, Capdevila JH. Characterization of 5,6- and 8,9-epoxyeicosatrienoic acids (5,6- and 8,9-EET) as potent in vivo angiogenic lipids. The Journal of Biological Chemistry. 280: 27138-46. PMID 15917237 DOI: 10.1074/Jbc.M501730200 |
0.37 |
|
| 2005 |
Weston AH, Félétou M, Vanhoutte PM, Falck JR, Campbell WB, Edwards G. Bradykinin-induced, endothelium-dependent responses in porcine coronary arteries: involvement of potassium channel activation and epoxyeicosatrienoic acids. British Journal of Pharmacology. 145: 775-784. PMID 15895105 DOI: 10.1038/Sj.Bjp.0706256 |
0.303 |
|
| 2005 |
Liclican EL, McGiff JC, Pedraza PL, Ferreri NR, Falck JR, Carroll MA. Exaggerated response to adenosine in kidneys from high salt-fed rats: role of epoxyeicosatrienoic acids. American Journal of Physiology. Renal Physiology. 289: F386-92. PMID 15814528 DOI: 10.1152/Ajprenal.00421.2004 |
0.34 |
|
| 2005 |
Drenjancevic-Peric I, Phillips SA, Falck JR, Lombard JH. Restoration of normal vascular relaxation mechanisms in cerebral arteries by chromosomal substitution in consomic SS.13BN rats. American Journal of Physiology. Heart and Circulatory Physiology. 289: H188-95. PMID 15778273 DOI: 10.1152/Ajpheart.00504.2004 |
0.307 |
|
| 2005 |
Krummen S, Falck JR, Thorin E. Two distinct pathways account for EDHF‐dependent dilatation in the gracilis artery of dyslipidaemic hApoB+/+ mice British Journal of Pharmacology. 145: 264-270. PMID 15765099 DOI: 10.1038/Sj.Bjp.0706194 |
0.307 |
|
| 2005 |
Yang W, Gauthier KM, Reddy LM, Sangras B, Sharma KK, Nithipatikom K, Falck JR, Campbell WB. Stable 5,6-epoxyeicosatrienoic acid analog relaxes coronary arteries through potassium channel activation. Hypertension. 45: 681-6. PMID 15699458 DOI: 10.1161/01.Hyp.0000153790.12735.F9 |
0.326 |
|
| 2005 |
Chen P, Guo M, Wygle D, Edwards PA, Falck JR, Roman RJ, Scicli AG. Inhibitors of cytochrome P450 4A suppress angiogenic responses. The American Journal of Pathology. 166: 615-24. PMID 15681843 DOI: 10.1016/S0002-9440(10)62282-1 |
0.349 |
|
| 2005 |
Sellers KW, Sun C, Diez-Freire C, Waki H, Morisseau C, Falck JR, Hammock BD, Paton JF, Raizada MK. Novel mechanism of brain soluble epoxide hydrolase-mediated blood pressure regulation in the spontaneously hypertensive rat. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 626-8. PMID 15659536 DOI: 10.1096/Fj.04-3128Fje |
0.323 |
|
| 2005 |
Randriamboavonjy V, Kiss L, Falck JR, Busse R, Fleming I. The synthesis of 20-HETE in small porcine coronary arteries antagonizes EDHF-mediated relaxation. Cardiovascular Research. 65: 487-494. PMID 15639488 DOI: 10.1016/J.Cardiores.2004.10.029 |
0.336 |
|
| 2005 |
Zhang F, Deng H, Kemp R, Singh H, Gopal VR, Falck JR, Laniado-Schwartzman M, Nasjletti A. Decreased levels of cytochrome P450 2E1-derived eicosanoids sensitize renal arteries to constrictor agonists in spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979). 45: 103-8. PMID 15569854 DOI: 10.1161/01.Hyp.0000150782.28485.91 |
0.346 |
|
| 2005 |
Gauthier KM, Baewer DV, Hittner S, Hillard CJ, Nithipatikom K, Reddy DS, Falck JR, Campbell WB. Endothelium-derived 2-arachidonylglycerol: an intermediate in vasodilatory eicosanoid release in bovine coronary arteries. American Journal of Physiology. Heart and Circulatory Physiology. 288: H1344-51. PMID 15528233 DOI: 10.1152/Ajpheart.00537.2004 |
0.327 |
|
| 2004 |
Harrington LS, Falck JR, Mitchell JA. Not so EEZE: The 'EDHF' antagonist 14, 15 epoxyeicosa-5(Z)-enoic acid has vasodilator properties in mesenteric arteries European Journal of Pharmacology. 506: 165-168. PMID 15588737 DOI: 10.1016/J.Ejphar.2004.09.062 |
0.372 |
|
| 2004 |
Gross ER, Nithipatikom K, Hsu AK, Peart JN, Falck JR, Campbell WB, Gross GJ. Cytochrome P450 omega-hydroxylase inhibition reduces infarct size during reperfusion via the sarcolemmal KATP channel. Journal of Molecular and Cellular Cardiology. 37: 1245-9. PMID 15572055 DOI: 10.1016/J.Yjmcc.2004.10.008 |
0.308 |
|
| 2004 |
Michaelis UR, Falck JR, Schmidt R, Busse R, Fleming I. Cytochrome P4502C9-Derived Epoxyeicosatrienoic Acids Induce the Expression of Cyclooxygenase-2 in Endothelial Cells Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 321-326. PMID 15569819 DOI: 10.1161/01.Atv.0000151648.58516.Eb |
0.352 |
|
| 2004 |
Caron N, El Hajjam A, Declèves AE, Joly E, Falck JR, Kramp R. Changes in renal haemodynamics induced by indomethacin in the rat involve cytochrome P450 arachidonic acid-dependent epoxygenases Clinical and Experimental Pharmacology and Physiology. 31: 683-690. PMID 15554908 DOI: 10.1111/J.0305-1870.2004.04066.X |
0.343 |
|
| 2004 |
Wei Y, Lin DH, Kemp R, Yaddanapudi GS, Nasjletti A, Falck JR, Wang WH. Arachidonic acid inhibits epithelial Na channel via cytochrome P450 (CYP) epoxygenase-dependent metabolic pathways. The Journal of General Physiology. 124: 719-27. PMID 15545402 DOI: 10.1085/Jgp.200409140 |
0.388 |
|
| 2004 |
Nithipatikom K, Gross ER, Endsley MP, Moore JM, Isbell MA, Falck JR, Campbell WB, Gross GJ. Inhibition of cytochrome P450omega-hydroxylase: a novel endogenous cardioprotective pathway. Circulation Research. 95: e65-71. PMID 15388642 DOI: 10.1161/01.Res.0000146277.62128.6F |
0.341 |
|
| 2004 |
Falck JR, Barma DK, Mohapatra S, Bandyopadhyay A, Reddy KM, Qi J, Campbell WB. Asymmetric synthesis of the stereoisomers of 11,12,15(S)-trihydroxyeicosa-5(Z),8(Z),13(E)-trienoic acid, a potent endothelium-derived vasodilator. Bioorganic & Medicinal Chemistry Letters. 14: 4987-90. PMID 15341965 DOI: 10.1016/J.Bmcl.2004.07.019 |
0.334 |
|
| 2004 |
Zghibeh CM, Gopal VR, Poff CD, Falck JR, Balazy M. Determination of trans-arachidonic acid isomers in human blood plasma Analytical Biochemistry. 332: 137-144. PMID 15301958 DOI: 10.1016/J.Ab.2004.04.030 |
0.33 |
|
| 2004 |
Ward NC, Rivera J, Hodgson J, Puddey IB, Beilin LJ, Falck JR, Croft KD. Urinary 20-Hydroxyeicosatetraenoic Acid Is Associated With Endothelial Dysfunction in Humans Circulation. 110: 438-443. PMID 15262846 DOI: 10.1161/01.Cir.0000136808.72912.D9 |
0.344 |
|
| 2004 |
Zhang F, Wang MH, Wang JS, Zand B, Gopal VR, Falck JR, Laniado-Schwartzman M, Nasjletti A. Transfection of CYP4A1 cDNA decreases diameter and increases responsiveness of gracilis muscle arterioles to constrictor stimuli. American Journal of Physiology. Heart and Circulatory Physiology. 287: H1089-95. PMID 15130884 DOI: 10.1152/Ajpheart.00627.2003 |
0.345 |
|
| 2004 |
Lombard JH, Frisbee JC, Roman RJ, Falck JR. Evaluation of cytochrome P450-4A omega-hydroxylase and 20-hydroxyeicosatetraenoic acid as an O2 sensing mechanism in the microcirculation. Methods in Enzymology. 381: 140-65. PMID 15063671 DOI: 10.1016/S0076-6879(04)81009-7 |
0.327 |
|
| 2004 |
Gauthier KM, Falck JR, Reddy LM, Campbell WB. 14,15-EET analogs: characterization of structural requirements for agonist and antagonist activity in bovine coronary arteries. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 49: 515-24. PMID 15026029 DOI: 10.1016/J.Phrs.2003.09.014 |
0.344 |
|
| 2004 |
Rajapakse NW, Roman RJ, Falck JR, Oliver JJ, Evans RG. Modulation of V1-receptor-mediated renal vasoconstriction by epoxyeicosatrienoic acids American Journal of Physiology-Regulatory Integrative and Comparative Physiology. 287: 181-187. PMID 14988086 DOI: 10.1152/Ajpregu.00555.2002 |
0.322 |
|
| 2004 |
Yu M, Cambj-Sapunar L, Kehl F, Maier KG, Takeuchi K, Miyata N, Ishimoto T, Reddy LM, Falck JR, Gebremedhin D, Harder DR, Roman RJ. Effects of a 20-HETE antagonist and agonists on cerebral vascular tone. European Journal of Pharmacology. 486: 297-306. PMID 14985052 DOI: 10.1016/J.Ejphar.2004.01.009 |
0.319 |
|
| 2004 |
Cheng MK, Doumad AB, Jiang H, Falck JR, McGiff JC, Carroll MA. Epoxyeicosatrienoic acids mediate adenosine-induced vasodilation in rat preglomerular microvessels (PGMV) via A2A receptors. British Journal of Pharmacology. 141: 441-8. PMID 14718251 DOI: 10.1038/Sj.Bjp.0705640 |
0.351 |
|
| 2004 |
Rivera J, Ward N, Hodgson J, Puddey IB, Falck JR, Croft KD. Measurement of 20-Hydroxyeicosatetraenoic Acid in Human Urine by Gas Chromatography-Mass Spectrometry Clinical Chemistry. 50: 224-226. PMID 14709657 DOI: 10.1373/Clinchem.2003.025775 |
0.353 |
|
| 2004 |
Jiang M, Mezentsev A, Kemp R, Byun K, Falck JR, Miano JM, Nasjletti A, Abraham NG, Laniado-Schwartzman M. Smooth muscle--specific expression of CYP4A1 induces endothelial sprouting in renal arterial microvessels. Circulation Research. 94: 167-74. PMID 14670847 DOI: 10.1161/01.Res.0000111523.12842.Fc |
0.309 |
|
| 2004 |
Xu F, Falck JR, Ortiz de Montellano PR, Kroetz DL. Catalytic activity and isoform-specific inhibition of rat cytochrome p450 4F enzymes. The Journal of Pharmacology and Experimental Therapeutics. 308: 887-95. PMID 14634044 DOI: 10.1124/Jpet.103.059626 |
0.604 |
|
| 2004 |
Kaduce TL, Fang X, Harmon SD, Oltman CL, Dellsperger KC, Teesch LM, Gopal VR, Falck JR, Campbell WB, Weintraub NL, Spector AA. 20-hydroxyeicosatetraenoic acid (20-HETE) metabolism in coronary endothelial cells. The Journal of Biological Chemistry. 279: 2648-56. PMID 14612451 DOI: 10.1074/Jbc.M306849200 |
0.376 |
|
| 2004 |
Wang D, Borrego-Conde LJ, Falck JR, Sharma KK, Wilcox CS, Umans JG. Contributions of nitric oxide, EDHF, and EETs to endothelium-dependent relaxation in renal afferent arterioles. Kidney International. 63: 2187-93. PMID 12753306 DOI: 10.1046/J.1523-1755.2003.00036.X |
0.308 |
|
| 2004 |
Kim JJ, Park YD, Cho SD, Kim HK, Kang YJ, Lee SG, Falck JR, Shiro M, Yoon YJ. Preparation of O-Alkylhydroxamic Acids Using 2-Acylpyridazin-3(2H)-ones in Water Bulletin of the Korean Chemical Society. 25: 1273-1276. DOI: 10.5012/Bkcs.2004.25.8.1273 |
0.324 |
|
| 2004 |
Cho SD, Park YD, Kim JJ, Falck JR, Yoon YJ. Facile Reduction of Carboxylic Acids, Esters, Acid Chlorides, Amides and Nitriles to Alcohols or Amines Using NaBH4/BF3·Et2O Bulletin of the Korean Chemical Society. 25: 407-409. DOI: 10.5012/Bkcs.2004.25.3.407 |
0.348 |
|
| 2004 |
Jagadeesh SG, Reddy LM, Nasjletti A, Falck JR. A concise synthesis of 12(S), 20-dihydroxyeicosa-5(Z), 8(Z), 10(E), 14(Z)-tetraenoic acid, an endogenous vasoconstrictor Tetrahedron Letters. 45: 7111-7113. DOI: 10.1016/J.Tetlet.2004.07.130 |
0.355 |
|
| 2004 |
Falck JR, Bandyopadhyay A, Barma DK, Shin DS, Kundu A, Kishore RVK. Stereoselective CrCl2-mediated condensation of aldehydes with functionalized 1,1,1-trichlorides: synthesis of trisubstituted (Z)-chloroolefins Tetrahedron Letters. 45: 3039-3042. DOI: 10.1016/J.Tetlet.2004.02.101 |
0.309 |
|
| 2003 |
Reddy YK, Reddy LM, Capdevila JH, Falck JR. Practical, asymmetric synthesis of 16-hydroxyeicosa-5(Z),8(Z), 11(Z),14(Z)-tetraenoic acid (16-HETE), an endogenous inhibitor of neutrophil activity. Bioorganic & Medicinal Chemistry Letters. 13: 3719-20. PMID 14552765 DOI: 10.1016/J.Bmcl.2003.08.005 |
0.343 |
|
| 2003 |
Gauthier KM, Jagadeesh SG, Falck JR, Campbell WB. 14,15-epoxyeicosa-5(Z)-enoic-mSI: a 14,15- and 5,6-EET antagonist in bovine coronary arteries. Hypertension. 42: 555-561. PMID 12953017 DOI: 10.1161/01.Hyp.0000091265.94045.C7 |
0.341 |
|
| 2003 |
Pomposiello SI, Quilley J, Carroll MA, Falck JR, McGiff JC. 5,6-epoxyeicosatrienoic acid mediates the enhanced renal vasodilation to arachidonic acid in the SHR. Hypertension. 42: 548-54. PMID 12939232 DOI: 10.1161/01.Hyp.0000090095.87899.36 |
0.373 |
|
| 2003 |
Patel S, Wohlfeil ER, Rademacher DJ, Carrier EJ, Perry LJ, Kundu A, Falck JR, Nithipatikom K, Campbell WB, Hillard CJ. The general anesthetic propofol increases brain N-arachidonylethanolamine (anandamide) content and inhibits fatty acid amide hydrolase. British Journal of Pharmacology. 139: 1005-13. PMID 12839875 DOI: 10.1038/Sj.Bjp.0705334 |
0.328 |
|
| 2003 |
Pfister SL, Spitzbarth N, Nithipatikom K, Falck JR, Campbell WB. Metabolism of 12-hydroperoxyeicosatetraenoic acid to vasodilatory trioxilin C3 by rabbit aorta. Biochimica Et Biophysica Acta. 1622: 6-13. PMID 12829255 DOI: 10.1016/S0304-4165(03)00097-7 |
0.346 |
|
| 2003 |
Grates HE, McGowen RM, Gupta SV, Falck JR, Brown TR, Callewaert DM, Sasaki DM. Quantification of 20-hydroxyeicosatetraenoic acid by colorimetric competitive enzyme linked immunosorbent assay. Journal of Biosciences. 28: 109-13. PMID 12682433 DOI: 10.1007/Bf02970140 |
0.326 |
|
| 2003 |
Ren Y, Garvin JL, Falck JR, Renduchintala KV, Carretero OA. Glomerular autacoids stimulated by bradykinin regulate efferent arteriole tone Kidney International. 63: 987-993. PMID 12631079 DOI: 10.1046/J.1523-1755.2003.00810.X |
0.313 |
|
| 2003 |
Kaide J, Wang MH, Wang JS, Zhang F, Gopal VR, Falck JR, Nasjletti A, Laniado-Schwartzman M. Transfection of CYP4A1 cDNA increases vascular reactivity in renal interlobar arteries. American Journal of Physiology. Renal Physiology. 284: F51-6. PMID 12388396 DOI: 10.1152/Ajprenal.00249.2002 |
0.374 |
|
| 2002 |
Sasaki DM, Yuan Y, Gikas K, Reddy M, Falck JR, Nithipatikom K, Campbell WB, Callewaert DM. Development of enzyme immunoassays for 5,6-, 8,9-, 11,12-, and 14,15- EETs and the corresponding DHETs. Advances in Experimental Medicine and Biology. 507: 531-6. PMID 12664636 DOI: 10.1007/978-1-4615-0193-0_81 |
0.365 |
|
| 2002 |
Capdevila JH, Falck JR. Biochemical and molecular properties of the cytochrome P450 arachidonic acid monooxygenases. Prostaglandins & Other Lipid Mediators. 68: 325-44. PMID 12432927 DOI: 10.1016/S0090-6980(02)00038-2 |
0.357 |
|
| 2002 |
Peng X, Carhuapoma JR, Bhardwaj A, Alkayed NJ, Falck JR, Harder DR, Traystman RJ, Koehler RC. Suppression of cortical functional hyperemia to vibrissal stimulation in the rat by epoxygenase inhibitors. American Journal of Physiology. Heart and Circulatory Physiology. 283: H2029-37. PMID 12384482 DOI: 10.1152/Ajpheart.01130.2000 |
0.308 |
|
| 2002 |
Cowart LA, Wei S, Hsu MH, Johnson EF, Krishna MU, Falck JR, Capdevila JH. The CYP4A isoforms hydroxylate epoxyeicosatrienoic acids to form high affinity peroxisome proliferator-activated receptor ligands. The Journal of Biological Chemistry. 277: 35105-12. PMID 12124379 DOI: 10.1074/Jbc.M201575200 |
0.386 |
|
| 2002 |
Frisbee JC, Maier KG, Falck JR, Roman RJ, Lombard JH. Integration of hypoxic dilation signaling pathways for skeletal muscle resistance arteries. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 283: R309-19. PMID 12121842 DOI: 10.1152/Ajpregu.00741.2001 |
0.311 |
|
| 2002 |
Capdevila JH, Harris RC, Falck JR. Microsomal cytochrome P450 and eicosanoid metabolism. Cellular and Molecular Life Sciences. 59: 780-789. PMID 12088278 DOI: 10.1007/S00018-002-8466-Y |
0.36 |
|
| 2002 |
Gauthier KM, Deeter C, Krishna UM, Reddy YK, Bondlela M, Falck JR, Campbell WB. 14,15-Epoxyeicosa-5(Z)-enoic Acid: A Selective Epoxyeicosatrienoic Acid Antagonist That Inhibits Endothelium-Dependent Hyperpolarization and Relaxation in Coronary Arteries Circulation Research. 90: 1028-1036. PMID 12016270 DOI: 10.1161/01.Res.0000018162.87285.F8 |
0.371 |
|
| 2002 |
Campbell WB, Deeter C, Gauthier KM, Ingraham RH, Falck JR, Li PL. 14,15-Dihydroxyeicosatrienoic acid relaxes bovine coronary arteries by activation of K(Ca) channels. American Journal of Physiology. Heart and Circulatory Physiology. 282: H1656-64. PMID 11959628 DOI: 10.1152/Ajpheart.00597.2001 |
0.314 |
|
| 2002 |
Frisbee JC, Krishna UM, Falck JR, Lombard JH. Role of prostanoids and 20-HETE in mediating oxygen-induced constriction of skeletal muscle resistance arteries. Microvascular Research. 62: 271-83. PMID 11678630 DOI: 10.1006/Mvre.2001.2341 |
0.326 |
|
| 2002 |
Falck JR, Mohapatra S, Bondlela M, Venkataraman SK. Homocoupling of alkyl-, alkenyl-, and arylboronic acids Tetrahedron Letters. 43: 8149-8151. DOI: 10.1016/S0040-4039(02)01897-X |
0.328 |
|
| 2001 |
Zhang F, Wang MH, Krishna UM, Falck JR, Laniado-Schwartzman M, Nasjletti A. Modulation by 20-HETE of phenylephrine-induced mesenteric artery contraction in spontaneously hypertensive and Wistar-Kyoto rats. Hypertension (Dallas, Tex. : 1979). 38: 1311-5. PMID 11751709 DOI: 10.1161/Hy1201.096116 |
0.327 |
|
| 2001 |
Nithipatikom K, Grall AJ, Holmes BB, Harder DR, Falck JR, Campbell WB. Liquid chromatographic-electrospray ionization-mass spectrometric analysis of cytochrome P450 metabolites of arachidonic acid. Analytical Biochemistry. 298: 327-36. PMID 11700990 DOI: 10.1006/Abio.2001.5395 |
0.329 |
|
| 2001 |
Zhao X, Inscho EW, Bondlela M, Falck JR, Imig JD. The CYP450 hydroxylase pathway contributes to P2X receptor-mediated afferent arteriolar vasoconstriction. American Journal of Physiology. Heart and Circulatory Physiology. 281: H2089-96. PMID 11668070 DOI: 10.1152/Ajpheart.2001.281.5.H2089 |
0.32 |
|
| 2001 |
Falck JR, Bondlela M, Venkataraman SK, Srinivas D. Bromo-boronolactonization of olefins. The Journal of Organic Chemistry. 66: 7148-50. PMID 11597243 DOI: 10.1021/Jo015838Z |
0.348 |
|
| 2001 |
Krishna UM, Reddy MM, Xia J, Falck JR, Balazy M. Stereospecific synthesis of trans-arachidonic acids. Bioorganic & Medicinal Chemistry Letters. 11: 2415-2418. PMID 11549436 DOI: 10.1016/S0960-894X(01)00442-5 |
0.369 |
|
| 2001 |
Frisbee JC, Roman RJ, Krishna UM, Falck JR, Lombard JH. Relative contributions of cyclooxygenase- and cytochrome P450 omega-hydroxylase-dependent pathways to hypoxic dilation of skeletal muscle resistance arteries. Journal of Vascular Research. 38: 305-14. PMID 11455201 DOI: 10.1159/000051061 |
0.372 |
|
| 2001 |
Yang B, Graham L, Dikalov S, Mason RP, Falck JR, Liao JK, Zeldin DC. Overexpression of cytochrome P450 CYP2J2 protects against hypoxia-reoxygenation injury in cultured bovine aortic endothelial cells. Molecular Pharmacology. 60: 310-320. PMID 11455018 DOI: 10.1124/Mol.60.2.310 |
0.318 |
|
| 2001 |
Capdevila JH, Falck JR. The CYP P450 arachidonic acid monooxygenases: From cell signaling to blood pressure regulation Biochemical and Biophysical Research Communications. 285: 571-576. PMID 11453630 DOI: 10.1006/Bbrc.2001.5167 |
0.334 |
|
| 2001 |
Imig JD, Falck JR, Wei S, Capdevila JH. Epoxygenase metabolites contribute to nitric oxide-independent afferent arteriolar vasodilation in response to bradykinin. Journal of Vascular Research. 38: 247-55. PMID 11399897 DOI: 10.1159/000051053 |
0.337 |
|
| 2001 |
Imig JD, Zhao X, Falck JR, Wei S, Capdevila JH. Enhanced renal microvascular reactivity to angiotensin II in hypertension is ameliorated by the sulfonimide analog of 11,12-epoxyeicosatrienoic acid. Journal of Hypertension. 19: 983-92. PMID 11393683 DOI: 10.1097/00004872-200105000-00020 |
0.332 |
|
| 2001 |
Alexander LD, Cui XL, Falck JR, Douglas JG. Arachidonic acid directly activates members of the mitogen-activated protein kinase superfamily in rabbit proximal tubule cells Kidney International. 59: 2039-2053. PMID 11380805 DOI: 10.1046/J.1523-1755.2001.00718.X |
0.387 |
|
| 2001 |
Cowart LA, Falck JR, Capdevila JH. Structural determinants of active site binding affinity and metabolism by cytochrome P450 BM-3. Archives of Biochemistry and Biophysics. 387: 117-24. PMID 11368173 DOI: 10.1006/Abbi.2000.2246 |
0.34 |
|
| 2001 |
Qu W, Bradbury JA, Tsao CC, Maronpot R, Harry GJ, Parker CE, Davis LS, Breyer MD, Waalkes MP, Falck JR, Chen J, Rosenberg RL, Zeldin DC. Cytochrome P450 CYP2J9, a new mouse arachidonic acid omega-1 hydroxylase predominantly expressed in brain. The Journal of Biological Chemistry. 276: 25467-79. PMID 11328810 DOI: 10.1074/Jbc.M100545200 |
0.32 |
|
| 2001 |
Nithipatikom K, DiCamelli RF, Kohler S, Gumina RJ, Falck JR, Campbell WB, Gross GJ. Determination of cytochrome P450 metabolites of arachidonic acid in coronary venous plasma during ischemia and reperfusion in dogs. Analytical Biochemistry. 292: 115-24. PMID 11319825 DOI: 10.1006/Abio.2001.5044 |
0.33 |
|
| 2001 |
Pomposiello SI, Carroll MA, Falck JR, McGiff JC. Epoxyeicosatrienoic acid-mediated renal vasodilation to arachidonic acid is enhanced in SHR. Hypertension. 37: 887-93. PMID 11244013 DOI: 10.1161/01.Hyp.37.3.887 |
0.343 |
|
| 2001 |
Frisbee JC, Roman RJ, Krishna UM, Falck JR, Lombard JH. 20-HETE modulates myogenic response of skeletal muscle resistance arteries from hypertensive Dahl-SS rats. American Journal of Physiology. Heart and Circulatory Physiology. 280: H1066-74. PMID 11179048 DOI: 10.1152/Ajpheart.2001.280.3.H1066 |
0.331 |
|
| 2001 |
Frisbee JC, Roman RJ, Krishna UM, Falck JR, Lombard JH. Altered mechanisms underlying hypoxic dilation of skeletal muscle resistance arteries of hypertensive versus normotensive Dahl rats. Microcirculation. 8: 115-127. DOI: 10.1038/Sj.Mn.7300150 |
0.334 |
|
| 2001 |
FRISBEE JC, ROMAN RJ, FALCK JR, KRISHNA UM, LOMBARD JH. 20-HETE Contributes to Myogenic Activation of Skeletal Muscle Resistance Arteries in Brown Norway and Sprague-Dawley Rats Microcirculation. 8: 45-55. DOI: 10.1038/Sj.Mn.7300148 |
0.354 |
|
| 2001 |
Falck J, Kumar P, Reddy Y, Zou G, Capdevila JH. Stereospecific synthesis of EET metabolites via Suzuki–Miyaura coupling Tetrahedron Letters. 42: 7211-7212. DOI: 10.1016/S0040-4039(01)01535-0 |
0.361 |
|
| 2001 |
Falck JR, Reddy YK, Haines DC, Reddy KM, Krishna UM, Graham S, Murry B, Peterson JA. Practical, enantiospecific syntheses of 14,15-EET and leukotoxin B (vernolic acid) Tetrahedron Letters. 42: 4131-4133. DOI: 10.1016/S0040-4039(01)00694-3 |
0.333 |
|
| 2001 |
Mohapatra S, Capdevila JH, Murphy RC, Hevko JM, Falck J. Efficient total synthesis of 5-oxo-6(E),8(Z),11(Z),14(Z)-eicosatetraenoic acid (5-oxo-ETE), a potent proinflammatory autacoid Tetrahedron Letters. 42: 4109-4110. DOI: 10.1016/S0040-4039(01)00668-2 |
0.323 |
|
| 2000 |
Bednar MM, Gross CE, Russell SR, Fuller SP, Ahern TP, Howard DB, Falck JR, Reddy KM, Balazy M. 16(R)-hydroxyeicosatetraenoic acid, a novel cytochrome P450 product of arachidonic acid, suppresses activation of human polymorphonuclear leukocyte and reduces intracranial pressure in a rabbit model of thromboembolic stroke. Neurosurgery. 47: 1410-8; discussion 1. PMID 11126912 DOI: 10.1097/00006123-200012000-00029 |
0.313 |
|
| 2000 |
Bhardwaj A, Northington FJ, Carhuapoma JR, Falck JR, Harder DR, Traystman RJ, Koehler RC. P-450 epoxygenase and NO synthase inhibitors reduce cerebral blood flow response to N-methyl-D-aspartate. American Journal of Physiology-Heart and Circulatory Physiology. 279. PMID 11009448 DOI: 10.1152/Ajpheart.2000.279.4.H1616 |
0.313 |
|
| 2000 |
Zhu D, Birks EK, Dawson CA, Patel M, Falck JR, Presberg K, Roman RJ, Jacobs ER. Hypoxic pulmonary vasoconstriction is modified by P-450 metabolites. American Journal of Physiology. Heart and Circulatory Physiology. 279: H1526-33. PMID 11009437 DOI: 10.1152/Ajpheart.2000.279.4.H1526 |
0.352 |
|
| 2000 |
Capdevila JH, Falck JR. Biochemical and molecular characteristics of the cytochrome P450 arachidonic acid monooxygenase Prostaglandins and Other Lipid Mediators. 62: 271-292. PMID 10963794 DOI: 10.1016/S0090-6980(00)00085-X |
0.335 |
|
| 2000 |
Sun CW, Falck JR, Okamoto H, Harder DR, Roman RJ. Role of cGMP versus 20-HETE in the vasodilator response to nitric oxide in rat cerebral arteries. American Journal of Physiology-Heart and Circulatory Physiology. 279. PMID 10899074 DOI: 10.1152/Ajpheart.2000.279.1.H339 |
0.306 |
|
| 2000 |
Gebremedhin D, Lange AR, Lowry TF, Taheri MR, Birks EK, Hudetz AG, Narayanan J, Falck JR, Okamoto H, Roman RJ, Nithipatikom K, Campbell WB, Harder DR. Production of 20-HETE and its role in autoregulation of cerebral blood flow Circulation Research. 87: 60-65. PMID 10884373 DOI: 10.1161/01.Res.87.1.60 |
0.344 |
|
| 2000 |
Hoch U, Falck JR, Ortiz De Montellano PR. Molecular basis for the ω-regiospecificity of the CYP4A2 and CYP4A3 fatty acid hydroxylases Journal of Biological Chemistry. 275: 26952-26958. PMID 10869363 DOI: 10.1074/Jbc.M004841200 |
0.576 |
|
| 2000 |
Bednar MM, Gross CE, Balazy MK, Belosludtsev Y, Colella DT, Falck JR, Balazy M. 16(R)-hydroxy-5,8,11,14-eicosatetraenoic acid, a new arachidonate metabolite in human polymorphonuclear leukocytes. Biochemical Pharmacology. 60: 447-55. PMID 10856441 DOI: 10.1016/S0006-2952(00)00345-2 |
0.386 |
|
| 2000 |
Frisbee JC, Falck JR, Lombard JH. Contribution of cytochrome P-450 omega-hydroxylase to altered arteriolar reactivity with high-salt diet and hypertension. American Journal of Physiology. Heart and Circulatory Physiology. 278: H1517-26. PMID 10775129 DOI: 10.1152/Ajpheart.2000.278.5.H1517 |
0.321 |
|
| 2000 |
Zhu D, Bousamra M, Zeldin DC, Falck JR, Townsley M, Harder DR, Roman RJ, Jacobs ER. Epoxyeicosatrienoic acids constrict isolated pressurized rabbit pulmonary arteries. American Journal of Physiology-Lung Cellular and Molecular Physiology. 278. PMID 10666118 DOI: 10.1152/Ajplung.2000.278.2.L335 |
0.302 |
|
| 2000 |
Imig JD, Pham BT, LeBlanc EA, Reddy KM, Falck JR, Inscho EW. Cytochrome P450 and cyclooxygenase metabolites contribute to the endothelin-1 afferent arteriolar vasoconstrictor and calcium responses. Hypertension (Dallas, Tex. : 1979). 35: 307-12. PMID 10642316 DOI: 10.1161/01.Hyp.35.1.307 |
0.315 |
|
| 2000 |
Chu ZM, Croft K, Kingsbury DA, Falck JR, Reddy KM, Beilin L. Cytochrome P450 metabolites of arachidonic acid may be important mediators in angiotensin II-induced vasoconstriction in the rat mesentery in vivo. Clinical Science. 98: 277-282. DOI: 10.1042/Cs19990217 |
0.384 |
|
| 1999 |
Alonso-Galicia M, Falck JR, Reddy KM, Roman RJ. 20-HETE agonists and antagonists in the renal circulation. American Journal of Physiology-Renal Physiology. 277. PMID 10564244 DOI: 10.1152/Ajprenal.1999.277.5.F790 |
0.313 |
|
| 1999 |
Imig JD, Falck JR, Inscho EW. Contribution of cytochrome P450 epoxygenase and hydroxylase pathways to afferent arteriolar autoregulatory responsiveness. British Journal of Pharmacology. 127: 1399-405. PMID 10455289 DOI: 10.1038/Sj.Bjp.0702662 |
0.308 |
|
| 1999 |
Nguyen X, Wang MH, Reddy KM, Falck JR, Schwartzman ML. Kinetic profile of the rat CYP4A isoforms: Arachidonic acid metabolism and isoform-specific inhibitors American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 276. PMID 10362749 DOI: 10.1152/Ajpregu.1999.276.6.R1691 |
0.404 |
|
| 1999 |
Truan G, Komandla MR, Falck JR, Peterson JA. P450BM-3: absolute configuration of the primary metabolites of palmitic acid. Archives of Biochemistry and Biophysics. 366: 192-8. PMID 10356283 DOI: 10.1006/Abbi.1999.1156 |
0.366 |
|
| 1999 |
Chen J, Wang DW, Falck JR, Capdevila J, Harris RC. Transfection of an active cytochrome P450 arachidonic acid epoxygenase indicates that 14,15-epoxyeicosatrienoic acid functions as an intracellular second messenger in response to epidermal growth factor Journal of Biological Chemistry. 274: 4764-4769. PMID 9988714 DOI: 10.1074/Jbc.274.8.4764 |
0.339 |
|
| 1999 |
Jacobs ER, Effros RM, Falck JR, Reddy KM, Campbell WB, Zhu D. Airway synthesis of 20-hydroxyeicosatetraenoic acid: metabolism by cyclooxygenase to a bronchodilator. American Journal of Physiology-Lung Cellular and Molecular Physiology. 276. PMID 9950890 DOI: 10.1152/Ajplung.1999.276.2.L280 |
0.332 |
|
| 1999 |
Sun C, Falck JR, Harder DR, Roman RJ. Role of Tyrosine Kinase and PKC in the Vasoconstrictor Response to 20-HETE in Renal Arterioles Hypertension. 33: 414-418. PMID 9931139 DOI: 10.1161/01.Hyp.33.1.414 |
0.3 |
|
| 1999 |
Rzigalinski BA, Willoughby KA, Hoffman SW, Falck JR, Ellis EF. Calcium influx factor, further evidence it is 5, 6-epoxyeicosatrienoic acid. The Journal of Biological Chemistry. 274: 175-82. PMID 9867827 DOI: 10.1074/Jbc.274.1.175 |
0.359 |
|
| 1999 |
Sasaki DM, Gikas K, Yuan Y, Schlicht J, Reddy RG, Reddy M, Falck JR, Nithipatikom K, DiCamelli RF, Kanai WB, Taber D, Morrow JD, Jackson Roberts L, Sarkar FH, Callewaert DM. Development of immunoassays for 5,6-, 8,9- 11,12-, and 14-15 epoxyeicosatrienoic acids (EETs) and corresponding dihydroxyeicosatrienoic acids (DHETs) Prostaglandins & Other Lipid Mediators. 59: 140. DOI: 10.1016/S0090-6980(99)90375-1 |
0.343 |
|
| 1999 |
Falck J, Krishna U, Capdevila JH. A synthesis of l-α-phosphatidyl-d-myo-inositol 4,5-bisphosphate (4,5-PIP2) and glyceryl lipid analogs Tetrahedron Letters. 40: 8771-8774. DOI: 10.1016/S0040-4039(99)01877-8 |
0.31 |
|
| 1998 |
Alonso-Galicia M, Sun CW, Falck JR, Harder DR, Roman RJ. Contribution of 20-HETE to the vasodilator actions of nitric oxide in renal arteries. American Journal of Physiology. Renal Physiology. 275: F370-F378. PMID 29591689 DOI: 10.1152/Ajprenal.1998.275.3.F370 |
0.352 |
|
| 1998 |
Sun C, Alonso-Galicia M, Taheri MR, Falck JR, Harder DR, Roman RJ. Nitric Oxide-20–Hydroxyeicosatetraenoic Acid Interaction in the Regulation of K+ Channel Activity and Vascular Tone in Renal Arterioles Circulation Research. 83: 1069-1079. PMID 9831701 DOI: 10.1161/01.Res.83.11.1069 |
0.333 |
|
| 1998 |
Pfister SL, Spitzbarth N, Nithipatikom K, Edgemond WS, Falck JR, Campbell WB. Identification of the 11,14,15- and 11,12, 15-trihydroxyeicosatrienoic acids as endothelium-derived relaxing factors of rabbit aorta. The Journal of Biological Chemistry. 273: 30879-87. PMID 9812980 DOI: 10.1074/Jbc.273.47.30879 |
0.387 |
|
| 1998 |
Chen JK, Falck JR, Reddy KM, Capdevila J, Harris RC. Epoxyeicosatrienoic Acids And Their Sulfonimide Derivatives Stimulate Tyrosine Phosphorylation And Induce Mitogenesis In Renal Epithelial Cells Journal of Biological Chemistry. 273: 29254-29261. PMID 9786938 DOI: 10.1074/Jbc.273.44.29254 |
0.302 |
|
| 1998 |
Dulin NO, Alexander LD, Harwalkar S, Falck JR, Douglas JG. Phospholipase A2-mediated activation of mitogen-activated protein kinase by angiotensin II Proceedings of the National Academy of Sciences of the United States of America. 95: 8098-8102. PMID 9653146 DOI: 10.1073/Pnas.95.14.8098 |
0.32 |
|
| 1998 |
Silverstein DM, Barac-Nieto M, Falck JR, Spitzer A. 20-HETE mediates the effect of parathyroid hormone and protein kinase C on renal phosphate transport. Prostaglandins Leukotrienes and Essential Fatty Acids. 58: 209-213. PMID 9610844 DOI: 10.1016/S0952-3278(98)90116-8 |
0.315 |
|
| 1998 |
Pratt PF, Falck JR, Reddy KM, Kurian JB, Campbell WB. 20-HETE relaxes bovine coronary arteries through the release of prostacyclin. Hypertension. 31: 237-41. PMID 9453309 DOI: 10.1161/01.Hyp.31.1.237 |
0.33 |
|
| 1998 |
Bhatt RK, Falck JR, Nigam S. Enantiospecific total synthesis of a novel arachidonic acid metabolite 3-hydroxyeicosatetraenoic acid Tetrahedron Letters. 39: 249-252. DOI: 10.1016/S0040-4039(97)10565-2 |
0.379 |
|
| 1997 |
Mao K, Reddy KK, Falck JR, McGiff JC, Balazy M. New group of lipid mediators containing omega-hydroxyarachadonic acid (20-HETE). Advances in Experimental Medicine and Biology. 433: 55-9. PMID 9561103 DOI: 10.1007/978-1-4899-1810-9_10 |
0.343 |
|
| 1997 |
Venter P, Kock JLF, Kumar GS, Botha A, Coetzee DJ, Botes PJ, Bhatt RK, Falck JR, Schewe T, Nigam S. Production of 3R-hydroxy-polyenoic fatty acids by the yeast Dipodascopsis uninucleata Lipids. 32: 1277-1283. PMID 9438238 DOI: 10.1007/S11745-006-0164-3 |
0.338 |
|
| 1997 |
Carroll MA, Balazy M, Huang DD, Rybalova S, Falck JR, McGiff JC. Cytochrome P450-derived renal HETEs: storage and release. Kidney International. 51: 1696-702. PMID 9186856 DOI: 10.1038/Ki.1997.234 |
0.317 |
|
| 1997 |
Wu S, Chen W, Murphy E, Gabel S, Tomer KB, Foley J, Steenbergen C, Falck JR, Moomaw CR, Zeldin DC. Molecular cloning, expression, and functional significance of a cytochrome P450 highly expressed in rat heart myocytes Journal of Biological Chemistry. 272: 12551-12559. PMID 9139707 DOI: 10.1074/Jbc.272.19.12551 |
0.371 |
|
| 1997 |
Nithipatikom K, Falck JR, Bhatt RK, Hanke CJ, Campbell WB. Determination of 14,15-epoxyeicosatrienoic acid and 14,15-dihydroxyeicosatrienoic acid by fluoroimmunoassay. Analytical Biochemistry. 246: 253-9. PMID 9073364 DOI: 10.1006/Abio.1997.2014 |
0.35 |
|
| 1997 |
Derman MP, Toker A, Hartwig JH, Spokes K, Falck JR, Chen CS, Cantley LC, Cantley LG. The lipid products of phosphoinositide 3-kinase increase cell motility through protein kinase C. The Journal of Biological Chemistry. 272: 6465-70. PMID 9045671 DOI: 10.1074/Jbc.272.10.6465 |
0.303 |
|
| 1997 |
Graham-Lorence S, Truan G, Peterson JA, Falck JR, Wei S, Helvig C, Capdevila JH. An active site substitution, F87V, converts cytochrome P450 BM-3 into a regio- and stereoselective (14S,15R)-arachidonic acid epoxygenase. The Journal of Biological Chemistry. 272: 1127-35. PMID 8995412 DOI: 10.1074/Jbc.272.2.1127 |
0.381 |
|
| 1997 |
Falck J, Belosludtsev YY, Reddy K, Reddy KM, Shortt M, Chauhan K, Capdevila JH, Wei S. Eicosanoid biosynthesis: differential inhibition of cytochrome P450 epoxygenase and ω-hydroxylase Bioorganic & Medicinal Chemistry Letters. 7: 3053-3056. DOI: 10.1016/S0960-894X(97)10144-5 |
0.376 |
|
| 1997 |
Reddy KM, Reddy KK, Falck JR. Synthesis of 2- and 5-diphospho-myo-inositol pentakisphosphate (2- and 5-PP-InsP5), intracellular mediators Tetrahedron Letters. 38: 4951-4952. DOI: 10.1016/S0040-4039(97)01088-5 |
0.311 |
|
| 1996 |
Lu M, Zhu Y, Balazy M, Reddy KM, Falck JR, Wang W. Effect of angiotensin II on the apical K+ channel in the thick ascending limb of the rat kidney. The Journal of General Physiology. 108: 537-547. PMID 8972391 DOI: 10.1085/Jgp.108.6.537 |
0.336 |
|
| 1996 |
Makita K, Falck JR, Capdevila JH. Cytochrome P450, the arachidonic acid cascade, and hypertension: New vistas for an old enzyme system Faseb Journal. 10: 1456-1463. PMID 8940291 DOI: 10.1096/Fasebj.10.13.8940291 |
0.396 |
|
| 1996 |
Zou AP, Fleming JT, Falck JR, Jacobs ER, Gebremedhin D, Harder DR, Roman RJ. Stereospecific effects of epoxyeicosatrienoic acids on renal vascular tone and K(+)-channel activity American Journal of Physiology-Renal Physiology. 270. PMID 8928844 DOI: 10.1152/Ajprenal.1996.270.5.F822 |
0.313 |
|
| 1996 |
Carroll MA, Balazy M, Margiotta P, Huang DD, Falck JR, McGiff JC. Cytochrome P-450-dependent HETEs: profile of biological activity and stimulation by vasoactive peptides. The American Journal of Physiology. 271: R863-9. PMID 8897975 DOI: 10.1152/Ajpregu.1996.271.4.R863 |
0.345 |
|
| 1996 |
Capdevila JH, Wei S, Helvig C, Falck JR, Belosludtsev Y, Truan G, Graham-Lorence SE, Peterson JA. The highly stereoselective oxidation of polyunsaturated fatty acids by cytochrome P450BM-3. The Journal of Biological Chemistry. 271: 22663-71. PMID 8798438 DOI: 10.1074/Jbc.271.37.22663 |
0.381 |
|
| 1996 |
Imig JD, Zou AP, Stec DE, Harder DR, Falck JR, Roman RJ. Formation and actions of 20-hydroxyeicosatetraenoic acid in rat renal arterioles. The American Journal of Physiology. 270: R217-27. PMID 8769805 DOI: 10.1152/Ajpregu.1996.270.1.R217 |
0.407 |
|
| 1996 |
Rosolowsky M, Falck JR, Campbell WB. Metabolism of arachidonic acid by canine polymorphonuclear leukocytes synthesis of lipoxygenase and omega-oxidized metabolites. Biochimica Et Biophysica Acta. 1300: 143-150. PMID 8652640 DOI: 10.1016/0005-2760(95)00238-3 |
0.385 |
|
| 1996 |
Wu S, Moomaw CR, Tomer KB, Falck JR, Zeldin DC. Molecular Cloning And Expression Of Cyp2J2, A Human Cytochrome P450 Arachidonic Acid Epoxygenase Highly Expressed In Heart Journal of Biological Chemistry. 271: 3460-3468. PMID 8631948 DOI: 10.1074/Jbc.271.7.3460 |
0.356 |
|
| 1996 |
Capdevila JH, Zeldin D, Karara A, Falck JR. Eicosanoid Metabolism and Bioactivation by Microsomal Cytochrome P450 Advances in Molecular and Cell Biology. 14: 317-339. DOI: 10.1016/S1569-2558(08)60348-3 |
0.343 |
|
| 1996 |
Heckmann B, Mioskowski C, Lumin S, Falck J, Wei S, Capdevila JH. Chiral acetals: Stereocontrolled syntheses of 16-, 17-, and 18-hydroxyeicosatetraenoic acids, cytochrome P-450 arachidonate metabolites Tetrahedron Letters. 37: 1425-1428. DOI: 10.1016/0040-4039(96)00059-7 |
0.371 |
|
| 1995 |
Fretland D, Anglin C, Baron D, Widomski D, Chauhan K, Bhatt R, Falck J. 3(S)-hydroxy-leukotriene B4 is a potent granulocyte chemotaxin in the guinea pig dermis. Inflammation Research. 44. PMID 8548366 DOI: 10.1007/Bf01778300 |
0.316 |
|
| 1995 |
Capdevila JH, Morrow JD, Belosludtsev YY, Beauchamp DR, DuBois RN, Falck JR. The catalytic outcomes of the constitutive and the mitogen inducible isoforms of prostaglandin H2 synthase are markedly affected by glutathione and glutathione peroxidase(s). Biochemistry. 34: 3325-37. PMID 7880828 DOI: 10.1021/Bi00010A023 |
0.357 |
|
| 1995 |
Powell WS, Hashefi M, Falck JR, Chauhan K, Rokach J, Wang SS, Mills E, MacLeod RJ. Effects of oxo and dihydro metabolites of 12-hydroxy-5,8,10,14-eicosatetraenoic acid on chemotaxis and cytosolic calcium levels in hum and neutrophils Journal of Leukocyte Biology. 57: 257-263. PMID 7852839 DOI: 10.1002/Jlb.57.2.257 |
0.302 |
|
| 1995 |
Zeldin DC, Wei S, Falck JR, Hammock BD, Snapper JR, Capdevila JH. Metabolism of epoxyeicosatrienoic acids by cytosolic epoxide hydrolase: substrate structural determinants of asymmetric catalysis. Archives of Biochemistry and Biophysics. 316: 443-51. PMID 7840649 DOI: 10.1006/Abbi.1995.1059 |
0.336 |
|
| 1995 |
Sakairi Y, Jacobson HR, Noland TD, Capdevila JH, Falck JR, Breyer MD. 5,6-EET inhibits ion transport in collecting duct by stimulating endogenous prostaglandin synthesis. The American Journal of Physiology. 268: F931-9. PMID 7771521 DOI: 10.1152/Ajprenal.1995.268.5.F931 |
0.318 |
|
| 1995 |
Zeldin DC, Plitman JD, Kobayashi J, Miller RF, Snapper JR, Falck JR, Szarek JL, Philpot RM, Capdevila JH. The rabbit pulmonary cytochrome P450 arachidonic acid metabolic pathway: characterization and significance. The Journal of Clinical Investigation. 95: 2150-60. PMID 7738183 DOI: 10.1172/Jci117904 |
0.388 |
|
| 1995 |
Zeldin DC, DuBois RN, Falck JR, Capdevila JH. Molecular cloning, expression and characterization of an endogenous human cytochrome P450 arachidonic acid epoxygenase isoform. Archives of Biochemistry and Biophysics. 322: 76-86. PMID 7574697 DOI: 10.1006/Abbi.1995.1438 |
0.333 |
|
| 1995 |
Zou AP, Muirhead EE, Cowley AW, Mattson DL, Falck JR, Jiang J, Roman RJ. Role of changes in renal hemodynamics and P-450 metabolites of arachidonic acid in the reversal of one-kidney, one clip hypertension. Journal of Hypertension. 13: 557-66. PMID 7561014 DOI: 10.1097/00004872-199505000-00012 |
0.353 |
|
| 1995 |
Lin F, Rios A, Falck JR, Belosludtsev Y, Schwartzman ML. 20-Hydroxyeicosatetraenoic acid is formed in response to EGF and is a mitogen in rat proximal tubule American Journal of Physiology - Renal Physiology. 269. DOI: 10.1152/Ajprenal.1995.269.6.F806 |
0.359 |
|
| 1994 |
Yamamoto S, Nishimura M, Conners MS, Stoltz RA, Falck JR, Chauhan K, Laniado-Schwartzman M. Oxidation and keto reduction of 12-hydroxy-5,8,10,14-eicosatetraenoic acids in bovine corneal epithelial microsomes. Biochimica Et Biophysica Acta. 1210: 217-225. PMID 8280773 DOI: 10.1016/0005-2760(94)90124-4 |
0.35 |
|
| 1994 |
Harder DR, Gebremedhin D, Narayanan J, Jefcoat C, Falck JR, Campbell WB, Roman R. Formation and action of a P-450 4A metabolite of arachidonic acid in cat cerebral microvessels. American Journal of Physiology-Heart and Circulatory Physiology. 266. PMID 8203608 DOI: 10.1152/Ajpheart.1994.266.5.H2098 |
0.372 |
|
| 1994 |
Ribeiro CM, Dubay GR, Falck JR, Mandel LJ. Parathyroid hormone inhibits Na(+)-K(+)-ATPase through a cytochrome P-450 pathway. The American Journal of Physiology. 266: F497-505. PMID 8160800 DOI: 10.1152/Ajprenal.1994.266.3.F497 |
0.319 |
|
| 1994 |
Zou AP, Imig JD, Ortiz de Montellano PR, Sui Z, Falck JR, Roman RJ. Effect of P-450 omega-hydroxylase metabolites of arachidonic acid on tubuloglomerular feedback. The American Journal of Physiology. 266: F934-41. PMID 8023972 DOI: 10.1152/Ajprenal.1994.266.6.F934 |
0.581 |
|
| 1994 |
Escalante B, Erlij D, Falck JR, McGiff JC. Cytochrome P-450 arachidonate metabolites affect ion fluxes in rabbit medullary thick ascending limb American Journal of Physiology-Cell Physiology. 266. PMID 8023907 DOI: 10.1152/Ajpcell.1994.266.6.C1775 |
0.322 |
|
| 1994 |
Makita K, Takahashi K, Karara A, Jacobson HR, Falck JR, Capdevila JH. Experimental and/or genetically controlled alterations of the renal microsomal cytochrome P450 epoxygenase induce hypertension in rats fed a high salt diet. The Journal of Clinical Investigation. 94: 2414-20. PMID 7989598 DOI: 10.1172/Jci117608 |
0.338 |
|
| 1994 |
Falck JR, Chauhan K, Rosolowsky M, Campbell WB. Vasoactive eicosanoids: Synthesis of 12,20-dihydroxyeicosa-5(Z),8(Z),10(E),14(Z)-tetraenoic acid via a novel chiral bis-lactol Bioorganic & Medicinal Chemistry Letters. 4: 2113-2116. DOI: 10.1016/S0960-894X(01)80112-8 |
0.339 |
|
| 1994 |
Chandrasekhar S, Yu J, Falck J, Mioskowski C. SmI2 mediated reductive addition of bis-phenylsulfones to ketones Tetrahedron Letters. 35: 5441-5444. DOI: 10.1016/S0040-4039(00)73520-9 |
0.504 |
|
| 1994 |
Yu J, Cho H, Chandrasekhar S, Falck J, Mioskowski C. Reductive lithiation of bis-phenylsulfones Tetrahedron Letters. 35: 5437-5440. DOI: 10.1016/S0040-4039(00)73519-2 |
0.492 |
|
| 1994 |
Belosludtsev YY, Kollah R, Falck J, Capdevila JH. Hepoxilins B3: Synthesis of all four stereoisomers and a glutathione adduct Tetrahedron Letters. 35: 5327-5330. DOI: 10.1016/S0040-4039(00)73491-5 |
0.319 |
|
| 1994 |
Falck J, Manna S, Chandrasekhar S, Alcaraz L, Mioskowski C. Terpenoid chirons: Preparation and transformations of 2-hydroxy-1,1,4a(R),6-tetramethyl-trans-Δ5,6-octalin Tetrahedron Letters. 35: 2013-2016. DOI: 10.1016/S0040-4039(00)73036-X |
0.527 |
|
| 1994 |
Chauhan K, Aravind S, Lee SG, Falck JR, Capdevila JH. vic-Diol chirons: Enantiospecific synthesis of 11,12- and 14,15-dihydroxyeicosatrienoic acids Tetrahedron Letters. 35: 6791-6794. DOI: 10.1016/0040-4039(94)85006-2 |
0.329 |
|
| 1993 |
Escalante B, Omata K, Sessa W, Lee SG, Falck JR, Schwartzman ML. 20-Hydroxyeicosatetraenoic acid is an endothelium-dependent vasoconstrictor in rabbit arteries European Journal of Pharmacology. 235: 1-7. PMID 8519270 DOI: 10.1016/0014-2999(93)90812-V |
0.388 |
|
| 1993 |
Ma YH, Gebremedhin D, Schwartzman ML, Falck JR, Clark JE, Masters BS, Harder DR, Roman RJ. 20-Hydroxyeicosatetraenoic acid is an endogenous vasoconstrictor of canine renal arcuate arteries. Circulation Research. 72: 126-36. PMID 8417836 DOI: 10.1161/01.Res.72.1.126 |
0.363 |
|
| 1993 |
Van Voorhis BJ, Dunn MS, Falck JR, Bhatt RK, VanRollins M, Snyder GD. Metabolism of arachidonic acid to epoxyeicosatrienoic acids by human granulosa cells may mediate steroidogenesis. The Journal of Clinical Endocrinology and Metabolism. 76: 1555-9. PMID 8388882 DOI: 10.1210/Jcem.76.6.8388882 |
0.377 |
|
| 1993 |
Imig JD, Falck JR, Gebremedhin D, Harder DR, Roman RJ. Elevated renovascular tone in young spontaneously hypertensive rats. Role of cytochrome P-450. Hypertension (Dallas, Tex. : 1979). 22: 357-64. PMID 8349328 DOI: 10.1161/01.Hyp.22.3.357 |
0.335 |
|
| 1993 |
Macica C, Balazy M, Falck JR, Mioskowski C, Carroll MA. Characterization of cytochrome P-450-dependent arachidonic acid metabolism in rabbit intestine. The American Journal of Physiology. 265: G735-41. PMID 8238357 DOI: 10.1152/Ajpgi.1993.265.4.G735 |
0.352 |
|
| 1993 |
Escalante B, Erlij D, Falck JR, McGiff JC. Cytochrome P450-dependent arachidonate metabolites affect renal transport in the rabbit. Journal of Cardiovascular Pharmacology. 22. PMID 7508012 DOI: 10.1097/00005344-199322002-00034 |
0.343 |
|
| 1993 |
Capdevila JH, Wei S, Kumar A, Kobayashi J, Snapper JR, Zeldin DC, Bhatt RK, Falck JR. Resolution of dihydroxyeicosanoates and of dihydroxyeicosatrienoates by chiral phase chromatography. Analytical Biochemistry. 207: 236-40. PMID 1481976 DOI: 10.1016/0003-2697(92)90006-S |
0.343 |
|
| 1993 |
Falck JR, Chandrasekhar S, Manna S, Chiu CCS, Mioskowski C, Wetzel I. Total synthesis of the spiro-o-benzoquinonefuran (-)-stypoldione Journal of the American Chemical Society. 115: 11606-11607. DOI: 10.1021/Ja00077A073 |
0.474 |
|
| 1993 |
Falck JR, Abdali A. Total synthesis of D-myo-inositole 3,4,5-trisphosphate and 1,3,4,5-tetrakisphosphate Bioorganic & Medicinal Chemistry Letters. 3: 717-720. DOI: 10.1016/S0960-894X(01)81261-0 |
0.326 |
|
| 1992 |
Capdevila JH, Dishman E, Karara A, Falck JR. Cytochrome P450 arachidonic acid epoxygenase: stereochemical characterization of epoxyeicosatrienoic acids. Methods in Enzymology. 206: 441-53. PMID 1784229 DOI: 10.1016/0076-6879(91)06113-H |
0.389 |
|
| 1992 |
Jajoo HK, Capdevila JH, Falck JR, Bhatt RK, Blair IA. Metabolism of 12(R)-hydroxyeicosatetraenoic acid by rat liver microsomes. Biochimica Et Biophysica Acta. 1123: 110-6. PMID 1730042 DOI: 10.1016/0005-2760(92)90177-W |
0.354 |
|
| 1992 |
Amruthesh SC, Falck JR, Ellis EF. Brain synthesis and cerebrovascular action of epoxygenase metabolites of arachidonic acid. Journal of Neurochemistry. 58: 503-10. PMID 1729396 DOI: 10.1111/J.1471-4159.1992.Tb09749.X |
0.356 |
|
| 1992 |
Prakash C, Zhang JY, Falck JR, Chauhan K, Blair IA. 20-Hydroxyeicosatetraenoic acid is excreted as a glucuronide conjugate in human urine. Biochemical and Biophysical Research Communications. 185: 728-33. PMID 1610364 DOI: 10.1016/0006-291X(92)91686-K |
0.352 |
|
| 1992 |
Capdevila JH, Falck JR, Estabrook RW. Cytochrome P450 and the arachidonate cascade. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 6: 731-6. PMID 1537463 DOI: 10.1096/Fasebj.6.2.1537463 |
0.341 |
|
| 1992 |
Gebremedhin D, Ma YH, Falck JR, Roman RJ, VanRollins M, Harder DR. Mechanism of action of cerebral epoxyeicosatrienoic acids on cerebral arterial smooth muscle. American Journal of Physiology-Heart and Circulatory Physiology. 263. PMID 1510149 DOI: 10.1152/Ajpheart.1992.263.2.H519 |
0.32 |
|
| 1992 |
Henrich WL, Falck JR, Campbell WB. Inhibition of renin secretion from rat renal cortical slices by (R)-12-HETE. American Journal of Physiology-Renal Physiology. 263. PMID 1415738 DOI: 10.1152/Ajprenal.1992.263.4.F665 |
0.339 |
|
| 1992 |
Capdevlla JH, Falck JR, Karara A. The Arachidonic Acid Epoxygenase: A Functional Role for Cytochrome P-460 in the Biosynthesis of Novel Lipid Derived Mediators Journal of Basic and Clinical Physiology and Pharmacology. 3: 49-49. DOI: 10.1515/Jbcpp.1992.3.S1.49 |
0.358 |
|
| 1992 |
Heckmann B, Alayrac C, Mioskowski C, Chandrasekhar S, Falck JR. Oxidative decarboxylation of mandelate ethers and α-substituted phenylacetates via dioxetanone generation Tetrahedron Letters. 33: 5205-5208. DOI: 10.1016/S0040-4039(00)79133-7 |
0.513 |
|
| 1992 |
Falck J, Lumin S, Lee S, Heckmann B, Mioskowski C, Karara A, Capdevila J. Enantiospecific synthesis of 17- and 18-hydroxyeicosatetraenoic acids, cytochrome P450 arachidonate metabolites Tetrahedron Letters. 33: 4893-4896. DOI: 10.1016/S0040-4039(00)61226-1 |
0.368 |
|
| 1991 |
Westlund P, Palmblad J, Falck JR, Lumin S. Synthesis, structural identification and biological activity of 11,12-dihydroxyeicosatetraenoic acids formed in human platelets. Biochimica Et Biophysica Acta. 1081: 301-307. PMID 1998749 DOI: 10.1016/0005-2760(91)90286-Q |
0.314 |
|
| 1991 |
Schwartzman ML, Omata K, Lin F, Bhatt RK, Falck J, Abraham NG. Detection of 20-hydroxyeicosatetrenoic acid in rat urine Biochemical and Biophysical Research Communications. 180: 445-449. PMID 1930236 DOI: 10.1016/S0006-291X(05)81313-0 |
0.341 |
|
| 1991 |
Nishimura M, Schwartzman ML, Falck JR, Lumin S, Zirrolli JA, Murphy RC. Metabolism of 12(R)-hydroxy-5,8,10,14-eicosatetraenoic acid (12(R)-HETE) in corneal tissues: Formation of novel metabolites Archives of Biochemistry and Biophysics. 290: 326-335. PMID 1929401 DOI: 10.1016/0003-9861(91)90548-W |
0.342 |
|
| 1991 |
Katoh T, Takahashi K, Capdevila J, Karara A, Falck JR, Jacobson HR, Badr KF. Glomerular stereospecific synthesis and hemodynamic actions of 8,9-epoxyeicosatrienoic acid in rat kidney. The American Journal of Physiology. 261: F578-86. PMID 1928373 DOI: 10.1152/Ajprenal.1991.261.4.F578 |
0.355 |
|
| 1991 |
Campbell WB, Brady MT, Rosolowsky LJ, Falck JR. Metabolism of arachidonic acid by rat adrenal glomerulosa cells: Synthesis of hydroxyeicosatetraenoic acids and epoxyeicosatrienoic acids Endocrinology. 128: 2183-2194. PMID 1900788 DOI: 10.1210/Endo-128-4-2183 |
0.404 |
|
| 1991 |
Pfister SL, Falck JR, Campbell WB. Enhanced synthesis of epoxyeicosatrienoic acids by cholesterol-fed rabbit aorta. American Journal of Physiology-Heart and Circulatory Physiology. 261. PMID 1887929 DOI: 10.1152/Ajpheart.1991.261.3.H843 |
0.332 |
|
| 1991 |
Escalante B, Erlij D, Falck JR, Mcgiff JC. Effect of cytochrome P450 arachidonate metabolites on ion transport in rabbit kidney loop of Henle. Science. 251: 799-802. PMID 1846705 DOI: 10.1126/Science.1846705 |
0.311 |
|
| 1991 |
Abraham NG, Feldman E, Falck JR, Lutton JD, Schwartzman ML. Modulation of erythropoiesis by novel human bone marrow cytochrome P450- dependent metabolites of arachidonic acid Blood. 78: 1461-1466. DOI: 10.1182/Blood.V78.6.1461.1461 |
0.364 |
|
| 1991 |
Bolitt V, Mioskowski C, Bhatt RK, Falck JR. Synthesis of (S)-(+)-mevalonolactone and mevalonate analogues Journal of Organic Chemistry. 56: 4238-4240. DOI: 10.1021/Jo00013A030 |
0.305 |
|
| 1991 |
Lumin S, Falck JR, Schwartzman ML. A concise synthesis of (R)-hydroxy-E,Z-diene fatty acids: preparation of 12(R)-hete, tetranor-12(R)-hete, and 13(R)-hode Tetrahedron Letters. 32: 2315-2318. DOI: 10.1016/S0040-4039(00)79912-6 |
0.307 |
|
| 1990 |
Hammonds TD, Blair IA, Falck JR, Capdevila JH. Resolution of epoxyeicosatrienoate enantiomers by chiral phase chromatography. Analytical Biochemistry. 182: 300-3. PMID 2610347 DOI: 10.1016/0003-2697(89)90598-8 |
0.316 |
|
| 1990 |
Karara A, Dishman E, Jacobson H, Falck JR, Capdevila JH. Arachidonic acid epoxygenase. Stereochemical analysis of the endogenous epoxyeicosatrienoic acids of human kidney cortex. Febs Letters. 268: 227-30. PMID 2384159 DOI: 10.1016/0014-5793(90)81014-F |
0.355 |
|
| 1990 |
Lin WK, Falck JR, Wong PYK. Effect of 14,15-epoxyeicosatrienoic acid infusion on blood pressure in normal and hypertensive rats. Biochemical and Biophysical Research Communications. 167: 977-981. PMID 2322287 DOI: 10.1016/0006-291X(90)90619-X |
0.342 |
|
| 1990 |
Capdevila JH, Falck JR, Dishman E, Karara A. Cytochrome P-450 arachidonate oxygenase. Methods in Enzymology. 187: 385-94. PMID 2233355 DOI: 10.1016/0076-6879(90)87045-5 |
0.358 |
|
| 1990 |
Falck JR, Yadagiri P, Capdevila J. Synthesis of epoxyeicosatrienoic acids and heteroatom analogs Methods in Enzymology. 187: 357-364. PMID 2233353 DOI: 10.1016/0076-6879(90)87042-2 |
0.405 |
|
| 1990 |
Wainwright S, Falck JR, Yadagiri P, Powell WS. Metabolism of 12(S)-hydroxy-5,8,10,14-eicosatetraenoic acid and other hydroxylated fatty acids by the reductase pathway in porcine polymorphonuclear leukocytes. Biochemistry. 29: 10126-35. PMID 2176862 DOI: 10.1021/Bi00495A017 |
0.381 |
|
| 1990 |
Wainwright S, Falck JR, Yadagiri P, Powell WS. Stereochemistry of leukotriene B4 metabolites formed by the reductase pathway in porcine polymorphonuclear leukocytes: inversion of stereochemistry of the 12-hydroxyl group. Biochemistry. 29: 1180-5. PMID 2157486 DOI: 10.1021/Bi00457A013 |
0.333 |
|
| 1990 |
Henrich WL, Falck JR, Campbell WB. Inhibition of renin release by 14,15-epoxyeicosatrienoic acid in renal cortical slices American Journal of Physiology-Endocrinology and Metabolism. 258. PMID 2154933 DOI: 10.1152/Ajpendo.1990.258.2.E269 |
0.335 |
|
| 1990 |
Carroll MA, Garcia MP, Falck JR, McGiff JC. 5,6-epoxyeicosatrienoic acid, a novel arachidonate metabolite. Mechanism of vasoactivity in the rat. Circulation Research. 67: 1082-8. PMID 2121384 DOI: 10.1161/01.Res.67.5.1082 |
0.376 |
|
| 1990 |
Takahashi K, Capdevila J, Karara A, Falck JR, Jacobson HR, Badr KF. Cytochrome P-450 arachidonate metabolites in rat kidney: characterization and hemodynamic responses. The American Journal of Physiology. 258: F781-9. PMID 2109933 DOI: 10.1152/Ajprenal.1990.258.4.F781 |
0.338 |
|
| 1990 |
Rosolowsky M, Falck JR, Willerson JT, Campbell WB. Synthesis of lipoxygenase and epoxygenase products of arachidonic acid by normal and stenosed canine coronary arteries. Circulation Research. 66: 608-621. PMID 2106399 DOI: 10.1161/01.Res.66.3.608 |
0.33 |
|
| 1990 |
Junier MP, Dray F, Blair I, Capdevila J, Dishman E, Falck JR, Ojeda SR. Epoxygenase products of arachidonic acid are endogenous constituents of the hypothalamus involved in D2 receptor-mediated, dopamine-induced release of somatostatin. Endocrinology. 126: 1534-40. PMID 1968382 DOI: 10.1210/Endo-126-3-1534 |
0.331 |
|
| 1990 |
Escalante B, Sessa WC, Falck JR, Yadagiri P, Schwartzman ML. Cytochrome P450-dependent arachidonic acid metabolites, 19- and 20-hydroxyeicosatetraenoic acids, enhance sodium-potassium ATPase activity in vascular smooth muscle Journal of Cardiovascular Pharmacology. 16: 438-443. PMID 1700215 DOI: 10.1097/00005344-199009000-00013 |
0.382 |
|
| 1990 |
Lumin S, Falck JR. Synthesis and stereochemical revision of a bioactive dihydroxyeicosanoid isolated from the red marine alga farlowia mollis Tetrahedron Letters. 31: 2971-2974. DOI: 10.1016/S0040-4039(00)89001-2 |
0.304 |
|
| 1989 |
Belardetti F, Campbell WB, Falck JR, Demontis G, Rosolowsky M. Products of heme-catalyzed transformation of the arachidonate derivative 12-HPETE open S-type K+ channels in Aplysia Neuron. 3: 497-505. PMID 2642008 DOI: 10.1016/0896-6273(89)90208-0 |
0.311 |
|
| 1989 |
Hirt DL, Capdevila J, Falck JR, Breyer MD, Jacobson HR. Cytochrome P450 metabolites of arachidonic acid are potent inhibitors of vasopressin action on rabbit cortical collecting duct. The Journal of Clinical Investigation. 84: 1805-12. PMID 2556446 DOI: 10.1172/Jci114365 |
0.339 |
|
| 1989 |
Ibe BO, Falck JR, Johnson AR, Campbell WB. Regulation of synthesis of prostacyclin and HETEs in human endothelial cells. The American Journal of Physiology. 256: C1168-75. PMID 2500022 DOI: 10.1152/Ajpcell.1989.256.6.C1168 |
0.408 |
|
| 1989 |
Proctor KG, Capdevila JH, Falck JR, Fitzpatrick FA, Mullane KM, McGriff JC. Cardiovascular and renal actions of cytochrome P-450 metabolites of arachidonic acid. Journal of Vascular Research. 26: 53-64. DOI: 10.1159/000158753 |
0.346 |
|
| 1989 |
Mosset P, Grée R, Falck JR. Synthesis of Two Intermediate Phosphonium Salts for 5,20 and 15,20-DiHetes Synthetic Communications. 19: 645-658. DOI: 10.1080/00397918908050711 |
0.387 |
|
| 1989 |
Falck JR, Yadagiri P. Enantiospecific synthesis of D-myo-inositol 1,4,5-trisphosphate from (-)-quinic acid Journal of Organic Chemistry. 54: 5851-5852. DOI: 10.1021/Jo00286A011 |
0.325 |
|
| 1989 |
Chabert P, Mioskowski C, Falck J. Synthesis of (±)-hepoxilin A3 utilizing arsonium ylides Tetrahedron Letters. 30: 2545-2548. DOI: 10.1016/S0040-4039(01)80446-9 |
0.305 |
|
| 1989 |
Shin DS, Yadagiri P, Falck JR, Masferrer JL, Schwartzman ML. Synthesis and Structure Confirmation Of Compound D, A Proinflammatory Arachidonate Metabolite Tetrahedron Letters. 30: 3923-3926. DOI: 10.1016/S0040-4039(00)99285-2 |
0.318 |
|
| 1989 |
Yadagiri P, Lumin S, Falck JR, Karara A, Capdevila J. Total synthesis of 5(S),12(S)- and 5(S),12(R)-dihydroxyeicosa-6(Z),8(E),14(Z)-trienoic acids, metabolites of leukotriene B4 Tetrahedron Letters. 30: 429-432. DOI: 10.1016/S0040-4039(00)95219-5 |
0.334 |
|
| 1988 |
Lapuerta L, Chacos N, Falck JR, Jacobson H, Capdevila JH. Renal microsomal cytochrome P-450 and the oxidative metabolism of arachidonic acid. The American Journal of the Medical Sciences. 295: 275-9. PMID 3364462 DOI: 10.1097/00000441-198804000-00010 |
0.376 |
|
| 1988 |
Capdevila JH, Mosset P, Yadagiri P, Lumin S, Falck JR. NADPH-dependent microsomal metabolism of 14,15-epoxyeicosatrienoic acid to diepoxides and epoxyalcohols. Archives of Biochemistry and Biophysics. 261: 122-33. PMID 3341770 DOI: 10.1016/0003-9861(88)90111-7 |
0.382 |
|
| 1988 |
Proctor KG, Shatkin S, Kaminski PM, Falck JR, Capdevila JH. Modulation of arteriolar blood flow by inhibitors of arachidonic acid oxidation after thermal injury: possible role for a novel class of vasodilator metabolites. Circulation. 77: 1185-96. PMID 3129211 DOI: 10.1161/01.Cir.77.5.1185 |
0.347 |
|
| 1988 |
Capdevila J, Gil L, Orellana M, Marnett LJ, Mason JI, Yadagiri P, Falck JR. Inhibitors of cytochrome P-450-dependent arachidonic acid metabolism. Archives of Biochemistry and Biophysics. 261: 257-63. PMID 3128168 DOI: 10.1016/0003-9861(88)90340-2 |
0.377 |
|
| 1988 |
Coceani F, Breen CA, Lees JG, Falck JR, Olley PM. Further evidence implicating a cytochrome P-450-mediated reaction in the contractile tension of the lamb ductus arteriosus. Circulation Research. 62: 471-477. PMID 3124973 DOI: 10.1161/01.Res.62.3.471 |
0.339 |
|
| 1988 |
Escalante B, Falck JR, Yadagiri P, Sun L, Laniado-Schwartzman M. 19(S)-hydroxyeicosatetraenoic acid is a potent stimulator of renal Na+-K+-ATPase. Biochemical and Biophysical Research Communications. 152: 1269-1274. PMID 2837181 DOI: 10.1016/S0006-291X(88)80422-4 |
0.363 |
|
| 1988 |
Reddy PSS, Yadagiri P, Lumin S, Shin DS, Falck JR. Modified pyridinium chlorochromate oxidation of aldehydes to carbamoyl azides/acyl azides or carboxylic acids Synthetic Communications. 18: 545-551. DOI: 10.1080/00397918808060749 |
0.351 |
|
| 1988 |
Yadagiri P, Shin DS, Falck JR. Enantiospecific synthesis of isomeric8,9,12-trihydroxyeicosa-5(Z),10(E),14(Z)-trienoic acids Tetrahedron Letters. 29: 5497-5500. DOI: 10.1016/S0040-4039(00)80796-0 |
0.354 |
|
| 1987 |
Carroll MA, Schwartzman M, Capdevila J, Falck JR, McGiff JC. Vasoactivity of arachidonic acid epoxides. European Journal of Pharmacology. 138: 281-3. PMID 3622613 DOI: 10.1016/0014-2999(87)90445-6 |
0.398 |
|
| 1987 |
Capdevila JH, Kishore V, Dishman E, Blair IA, Falck JR. A novel pool of rat liver inositol and ethanolamine phospholipids contains epoxyeicosatrienoic acids (EETs). Biochemical and Biophysical Research Communications. 146: 638-44. PMID 3619897 DOI: 10.1016/0006-291X(87)90576-6 |
0.316 |
|
| 1987 |
Lumin S, Yadagiri P, Falck JR, Capdevila J, Mosset P, Grée R. Total synthesis of 5(S),20- and 15(S),20-dihydroxyeicosatetraenoic acid and 5(S),6(R)-epoxy-20-hydroxy- and 14(R),15(S)-epoxy-20-hydroxyeicosatreinoic acid Journal of the Chemical Society, Chemical Communications. 389-390. DOI: 10.1039/C39870000389 |
0.308 |
|
| 1986 |
Capdevila J, Yadagiri P, Manna S, Falck JR. Absolute configuration of the hydroxyeicosatetraenoic acids (HETEs) formed during catalytic oxygenation of arachidonic acid by microsomal cytochrome P-450 Biochemical and Biophysical Research Communications. 141: 1007-1011. PMID 3101677 DOI: 10.1016/S0006-291X(86)80144-9 |
0.385 |
|
| 1986 |
Yadagiri P, Lumin S, Hosset P, Capdevila J, Falck J. Enantiospecific total synthesis of 8- and 12-hydroxyeicosatetraenoic acid Tetrahedron Letters. 27: 6039-6040. DOI: 10.1016/S0040-4039(00)85392-7 |
0.368 |
|
| 1986 |
Mosset P, Yadagiri P, Lumin S, Capdevila J, Falck J. Arachidonate epoxygenase: Total synthesis of both enantiomers of 8,9- and 11,12-epoxyricosatrienoic acid Tetrahedron Letters. 27: 6035-6038. DOI: 10.1016/S0040-4039(00)85391-5 |
0.361 |
|
| 1986 |
Moustakis CA, Weerasinghe D, Mosset P, Falck J, Mioskowski C. Synthesis of 12(R),13(S)-oxido-9-octadecenoic (vernolic) and 13(S)-hydroxy-9, 11-octadecadienoic (coriolic) acids Tetrahedron Letters. 27: 303-304. DOI: 10.1016/S0040-4039(00)84002-2 |
0.364 |
|
| 1985 |
Spearman ME, Prough RA, Estabrook RW, Falck JR, Manna S, Leibman KC, Murphy RC, Capdevila J. Novel glutathione conjugates formed from epoxyeicosatrienoic acids (EETs). Archives of Biochemistry and Biophysics. 242: 225-30. PMID 4051502 DOI: 10.1016/0003-9861(85)90496-5 |
0.326 |
|
| 1985 |
Capdevila J, Kim YR, Martin-Wixtrom C, Falck JR, Manna S, Estabrook RW. Influence of a fibric acid type of hypolipidemic agent on the oxidative metabolism of arachidonic acid by liver microsomal cytochrome P-450. Archives of Biochemistry and Biophysics. 243: 8-19. PMID 3933431 DOI: 10.1016/0003-9861(85)90768-4 |
0.372 |
|
| 1985 |
Campbell WB, Falck JR, Okita JR, Johnson AR, Callahan KS. Synthesis of dihomoprostaglandins from adrenic acid (7,10,13,16-docosatetraenoic acid) by human endothelial cells Biochimica Et Biophysica Acta. 837: 67-76. PMID 3931686 DOI: 10.1016/0005-2760(85)90086-4 |
0.365 |
|
| 1985 |
Negro-Vilar A, Snyder GD, Falck JR, Manna S, Chacos N, Capdevila J. Involvement of Eicosanoids in Release of Oxytocin and Vasopressin from the Neural Lobe of the Rat Pituitary Endocrinology. 116: 2663-2668. PMID 3922746 DOI: 10.1210/Endo-116-6-2663 |
0.337 |
|
| 1985 |
Falck J, Manna S, Viala J, Siddhanta AK, Moustakis CA, Capdevila J. Arachidonate epoxygenase: inhibitors and metabolite analogues Tetrahedron Letters. 26: 2287-2290. DOI: 10.1016/S0040-4039(00)95076-7 |
0.35 |
|
| 1984 |
Capdevila J, Pramanik B, Napoli JL, Manna S, Falck JR. Arachidonic acid epoxidation: epoxyeicosatrienoic acids are endogenous constituents of rat liver. Archives of Biochemistry and Biophysics. 231: 511-7. PMID 6732246 DOI: 10.1016/0003-9861(84)90415-6 |
0.336 |
|
| 1984 |
Capdevila J, Snijder GD, Falck JR. Epoxygenation of arachidonic acid by rat anterior pituitary microsomal fractions Febs Letters. 178: 319-322. PMID 6439577 DOI: 10.1016/0014-5793(84)80625-0 |
0.359 |
|
| 1984 |
Falck JR, Manna S, Capdevila J. Enantiospecific synthesis of methyl 11,12- and 14,15-epoxyeicosatrienoate Tetrahedron Letters. 25: 2443-2446. DOI: 10.1016/S0040-4039(01)81200-4 |
0.312 |
|
| 1984 |
Falck JR, Siddhanta AK, Estabrook RW, Capdevila J, Mioskowski C. 5- and 8-HETE production by rat hepatic microsomal cytochrome P-450 Tetrahedron Letters. 25: 1457-1458. DOI: 10.1016/S0040-4039(01)80185-4 |
0.324 |
|
| 1984 |
Capdevila J, Snyder GG, Falck JR, Estabrook RW. The cytochrome P450-dependent metabolism of arachidonic acid Prostaglandins. 28: 659. DOI: 10.1016/0090-6980(84)90160-6 |
0.395 |
|
| 1984 |
Falck JR, Manna S, Jacobson HR, Estabrook RW, Chacos N, Capdevila J. Absolute configuration of epoxyeicosatrienoic acids (EETs) formed during catalytic oxygenation of arachidonic acid by purified rat liver microsomal cytochrome P-450 Journal of the American Chemical Society. 106: 3334-3336. DOI: 10.1002/Chin.198436170 |
0.349 |
|
| 1983 |
Snyder GD, Capdevila J, Chacos N, Manna S, Falck JR. Action of luteinizing hormone-releasing hormone: involvement of novel arachidonic acid metabolites. Proceedings of the National Academy of Sciences of the United States of America. 80: 3504-3507. PMID 6344087 DOI: 10.1073/Pnas.80.11.3504 |
0.315 |
|
| 1983 |
Falck JR, Manna S, Siddhanta AK, Capdevila J, Buynak JD. Transformation of 15-hete to 14,15-dihydroxyeicosatrienoic acid and 11,14,15- and 13,14,15-trihydroxyeicosatrienoic acid Tetrahedron Letters. 24: 5715-5718. DOI: 10.1016/S0040-4039(00)94181-9 |
0.338 |
|
| 1983 |
Manna S, Falck JR, Chacos N, Capdevila J. Synthesis of arachidonic acid metabolites produced by purified kidney cortex microsomal cytochrome P-450 Tetrahedron Letters. 24: 33-36. DOI: 10.1016/S0040-4039(00)81319-2 |
0.367 |
|
| 1982 |
Falck JR, Manna S. 8,9-Epoxyarachinodic acid: a cytochrome P-450 metabolite Tetrahedron Letters. 23: 1755-1756. DOI: 10.1016/S0040-4039(00)86732-5 |
0.36 |
|
| 1981 |
Falck JR, Manna S. An intramolecular passerini reaction: Synthesis of hydrastine. Tetrahedron Letters. 22: 619-620. DOI: 10.1016/S0040-4039(01)92504-3 |
0.314 |
|
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