Patrick Aloy - Publications

Affiliations: 
Structural and Computational Biology Institute for Research in Biomedicine Barcelona, IRB 

104 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Kim DK, Weller B, Lin CW, Sheykhkarimli D, Knapp JJ, Dugied G, Zanzoni A, Pons C, Tofaute MJ, Maseko SB, Spirohn K, Laval F, Lambourne L, Kishore N, Rayhan A, ... ... Aloy P, et al. A proteome-scale map of the SARS-CoV-2-human contactome. Nature Biotechnology. PMID 36217029 DOI: 10.1038/s41587-022-01475-z  0.68
2020 van Leeuwen J, Pons C, Tan G, Wang JZ, Hou J, Weile J, Gebbia M, Liang W, Shuteriqi E, Li Z, Lopes M, Ušaj M, Dos Santos Lopes A, van Lieshout N, Myers CL, ... ... Aloy P, et al. Systematic analysis of bypass suppression of essential genes. Molecular Systems Biology. 16: e9828. PMID 32939983 DOI: 10.15252/Msb.20209828  0.343
2020 Mateo L, Duran-Frigola M, Gris-Oliver A, Palafox M, Scaltriti M, Razavi P, Chandarlapaty S, Arribas J, Bellet M, Serra V, Aloy P. Personalized cancer therapy prioritization based on driver alteration co-occurrence patterns. Genome Medicine. 12: 78. PMID 32907621 DOI: 10.1186/S13073-020-00774-X  0.338
2020 Duran-Frigola M, Bertoni M, Blanco R, Martínez V, Pauls E, Alcalde V, Turon G, Villegas N, Fernández-Torras A, Pons C, Mateo L, Guitart-Pla O, Badia-I-Mompel P, Gimeno A, Soler N, ... ... Aloy P, et al. Bioactivity Profile Similarities to Expand the Repertoire of COVID-19 Drugs. Journal of Chemical Information and Modeling. PMID 32672454 DOI: 10.1021/Acs.Jcim.0C00420  0.304
2020 Duran-Frigola M, Pauls E, Guitart-Pla O, Bertoni M, Alcalde V, Amat D, Juan-Blanco T, Aloy P. Extending the small-molecule similarity principle to all levels of biology with the Chemical Checker. Nature Biotechnology. PMID 32440005 DOI: 10.1038/S41587-020-0502-7  0.343
2020 Luck K, Kim DK, Lambourne L, Spirohn K, Begg BE, Bian W, Brignall R, Cafarelli T, Campos-Laborie FJ, Charloteaux B, Choi D, Coté AG, Daley M, Deimling S, Desbuleux A, ... ... Aloy P, et al. A reference map of the human binary protein interactome. Nature. 580: 402-408. PMID 32296183 DOI: 10.1038/S41586-020-2188-X  0.48
2020 Mattiazzi Usaj M, Sahin N, Friesen H, Pons C, Usaj M, Masinas MPD, Shuteriqi E, Shkurin A, Aloy P, Morris Q, Boone C, Andrews BJ. Systematic genetics and single-cell imaging reveal widespread morphological pleiotropy and cell-to-cell variability. Molecular Systems Biology. 16: e9243. PMID 32064787 DOI: 10.15252/Msb.20199243  0.303
2019 Iglesias V, Paladin L, Juan-Blanco T, Pallarès I, Aloy P, Tosatto SCE, Ventura S. Characterization of Human Prion-Like Proteins: Beyond Neurological Diseases. Frontiers in Physiology. 10: 314. PMID 30971948 DOI: 10.3389/Fphys.2019.00314  0.45
2019 Fernández-Torras A, Duran-Frigola M, Aloy P. Encircling the regions of the pharmacogenomic landscape that determine drug response. Genome Medicine. 11: 17. PMID 30914058 DOI: 10.1186/S13073-019-0626-X  0.308
2018 Bertoni M, Aloy P. DynBench3D, a Web-Resource to Dynamically Generate Benchmark Sets of Large Heteromeric Protein Complexes. Journal of Molecular Biology. 430: 4431-4438. PMID 30274705 DOI: 10.1016/J.Jmb.2018.09.011  0.377
2018 Juan-Blanco T, Duran-Frigola M, Aloy P. Rationalizing Drug Response in Cancer Cell Lines. Journal of Molecular Biology. 430: 3016-3027. PMID 29626539 DOI: 10.1016/J.Jmb.2018.03.021  0.335
2018 Wuchty S, Mueller S, Caufield H, Haeuser R, Aloy P, Kalkhof S, Uetz P. Proteome data improves protein function prediction in the interactome of H. pylori. Molecular & Cellular Proteomics : McP. PMID 29414760 DOI: 10.1074/Mcp.Ra117.000474  0.48
2017 Weile J, Sun S, Cote AG, Knapp J, Verby M, Mellor JC, Wu Y, Pons C, Wong C, van Lieshout N, Yang F, Tasan M, Tan G, Yang S, Fowler DM, ... ... Aloy P, et al. A framework for exhaustively mapping functional missense variants. Molecular Systems Biology. 13: 957. PMID 29269382 DOI: 10.15252/Msb.20177908  0.354
2017 Duran-Frigola M, Siragusa L, Ruppin E, Barril X, Cruciani G, Aloy P. Detecting similar binding pockets to enable systems polypharmacology. Plos Computational Biology. 13: e1005522. PMID 28662117 DOI: 10.1371/Journal.Pcbi.1005522  0.409
2017 Duran-Frigola M, Mateo L, Aloy P. Drug repositioning beyond the low-hanging fruits Current Opinion in Systems Biology. 3: 95-102. DOI: 10.1016/J.Coisb.2017.04.010  0.31
2016 Jaeger S, Igea A, Arroyo R, Alcalde V, Canovas B, Orozco M, Nebreda AR, Aloy P. Quantification of pathway crosstalk reveals novel synergistic drug combinations for breast cancer. Cancer Research. PMID 27879272 DOI: 10.1158/0008-5472.Can-16-0097  0.317
2016 van Leeuwen J, Pons C, Mellor JC, Yamaguchi TN, Friesen H, Koschwanez J, Ušaj MM, Pechlaner M, Takar M, Ušaj M, VanderSluis B, Andrusiak K, Bansal P, Baryshnikova A, Boone CE, ... ... Aloy P, et al. Exploring genetic suppression interactions on a global scale. Science (New York, N.Y.). 354. PMID 27811238 DOI: 10.1126/Science.Aag0839  0.318
2016 Zhong Q, Pevzner SJ, Hao T, Wang Y, Mosca R, Menche J, Taipale M, Taşan M, Fan C, Yang X, Haley P, Murray RR, Mer F, Gebreab F, Tam S, ... ... Aloy P, et al. An inter-species protein-protein interaction network across vast evolutionary distance. Molecular Systems Biology. 12: 865. PMID 27107014 DOI: 10.15252/Msb.20156484  0.433
2016 Yachie N, Petsalaki E, Mellor JC, Weile J, Jacob Y, Verby M, Ozturk SB, Li S, Cote AG, Mosca R, Knapp JJ, Ko M, Yu A, Gebbia M, Sahni N, ... ... Aloy P, et al. Pooled-matrix protein interaction screens using Barcode Fusion Genetics. Molecular Systems Biology. 12: 863. PMID 27107012 DOI: 10.15252/Msb.20156660  0.399
2016 Yang X, Coulombe-Huntington J, Kang S, Sheynkman GM, Hao T, Richardson A, Sun S, Yang F, Shen YA, Murray RR, Spirohn K, Begg BE, Duran-Frigola M, MacWilliams A, Pevzner SJ, ... ... Aloy P, et al. Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing. Cell. 164: 805-817. PMID 26871637 DOI: 10.1016/J.Cell.2016.01.029  0.46
2016 Herrando-Grabulosa M, Mulet R, Pujol A, Mas JM, Navarro X, Aloy P, Coma M, Casas C. Novel Neuroprotective Multicomponent Therapy for Amyotrophic Lateral Sclerosis Designed by Networked Systems. Plos One. 11: e0147626. PMID 26807587 DOI: 10.1371/Journal.Pone.0147626  0.327
2016 Kumar A, Beloglazova N, Bundalovic-Torma C, Phanse S, Deineko V, Gagarinova A, Musso G, Vlasblom J, Lemak S, Hooshyar M, Minic Z, Wagih O, Mosca R, Aloy P, Golshani A, et al. Conditional Epistatic Interaction Maps Reveal Global Functional Rewiring of Genome Integrity Pathways in Escherichia coli. Cell Reports. 14: 648-61. PMID 26774489 DOI: 10.1016/J.Celrep.2015.12.060  0.374
2016 Sfriso P, Duran-Frigola M, Mosca R, Emperador A, Aloy P, Orozco M. Residues Coevolution Guides the Systematic Identification of Alternative Functional Conformations in Proteins. Structure (London, England : 1993). 24: 116-26. PMID 26688214 DOI: 10.1016/J.Str.2015.10.025  0.376
2016 Ho AD, Horn P, Hennrich M, Jaeger S, Romanov N, Ding X, Bork P, Aloy P, Gavin A. Proteomics Analysis of Cellular Network in Human Bone Marrow Reveals Lineage Skewing Towards Megakaryocytes and Decrease in Lymphoid Development upon Aging Blood. 128: 2658-2658. DOI: 10.1182/Blood.V128.22.2658.2658  0.338
2015 Segura J, Sorzano CO, Cuenca-Alba J, Aloy P, Carazo JM. Using neighborhood cohesiveness to infer interactions between protein domains. Bioinformatics (Oxford, England). 31: 2545-52. PMID 25838464 DOI: 10.1093/Bioinformatics/Btv188  0.438
2015 Casas C, Isus L, Herrando-Grabulosa M, Mancuso FM, Borrás E, Sabidó E, Forés J, Aloy P. Network-based proteomic approaches reveal the neurodegenerative, neuroprotective and pain-related mechanisms involved after retrograde axonal damage. Scientific Reports. 5: 9185. PMID 25784190 DOI: 10.1038/Srep09185  0.351
2015 Mosca R, Tenorio-Laranga J, Olivella R, Alcalde V, Céol A, Soler-López M, Aloy P. dSysMap: exploring the edgetic role of disease mutations. Nature Methods. 12: 167-8. PMID 25719824 DOI: 10.1038/Nmeth.3289  0.375
2015 Arroyo R, Suñé G, Zanzoni A, Duran-Frigola M, Alcalde V, Stracker TH, Soler-López M, Aloy P. Systematic identification of molecular links between core and candidate genes in breast cancer. Journal of Molecular Biology. 427: 1436-1450. PMID 25640309 DOI: 10.1016/J.Jmb.2015.01.014  0.734
2015 Capdevila-Busquets E, Badiola N, Arroyo R, Alcalde V, Soler-López M, Aloy P. Breast cancer genes PSMC3IP and EPSTI1 play a role in apoptosis regulation. Plos One. 10: e0115352. PMID 25590583 DOI: 10.1371/Journal.Pone.0115352  0.339
2015 Jin K, Musso G, Vlasblom J, Jessulat M, Deineko V, Negroni J, Mosca R, Malty R, Nguyen-Tran DH, Aoki H, Minic Z, Freywald T, Phanse S, Xiang Q, Freywald A, ... Aloy P, et al. Yeast mitochondrial protein-protein interactions reveal diverse complexes and disease-relevant functional relationships. Journal of Proteome Research. 14: 1220-37. PMID 25546499 DOI: 10.1021/Pr501148Q  0.391
2015 Juan-Blanco T, Duran-Frigola M, Aloy P. IntSide: a web server for the chemical and biological examination of drug side effects. Bioinformatics (Oxford, England). 31: 612-3. PMID 25380960 DOI: 10.1093/Bioinformatics/Btu688  0.372
2014 Blasche S, Arens S, Ceol A, Siszler G, Schmidt MA, Häuser R, Schwarz F, Wuchty S, Aloy P, Uetz P, Stradal T, Koegl M. The EHEC-host interactome reveals novel targets for the translocated intimin receptor. Scientific Reports. 4: 7531. PMID 25519916 DOI: 10.1038/Srep07531  0.442
2014 Duran-Frigola M, Rossell D, Aloy P. A chemo-centric view of human health and disease. Nature Communications. 5: 5676. PMID 25435099 DOI: 10.1038/Ncomms6676  0.354
2014 Rolland T, TaÅŸan M, Charloteaux B, Pevzner SJ, Zhong Q, Sahni N, Yi S, Lemmens I, Fontanillo C, Mosca R, Kamburov A, Ghiassian SD, Yang X, Ghamsari L, Balcha D, ... ... Aloy P, et al. A proteome-scale map of the human interactome network. Cell. 159: 1212-26. PMID 25416956 DOI: 10.1016/J.Cell.2014.10.050  0.363
2014 Negroni J, Mosca R, Aloy P. Assessing the applicability of template-based protein docking in the twilight zone. Structure (London, England : 1993). 22: 1356-1362. PMID 25156427 DOI: 10.1016/J.Str.2014.07.009  0.416
2014 Pache RA, Aloy P. Increasing the precision of orthology-based complex prediction through network alignment. Peerj. 2: e413. PMID 24918034 DOI: 10.7717/Peerj.413  0.424
2014 Häuser R, Ceol A, Rajagopala SV, Mosca R, Siszler G, Wermke N, Sikorski P, Schwarz F, Schick M, Wuchty S, Aloy P, Uetz P. A second-generation protein-protein interaction network of Helicobacter pylori. Molecular & Cellular Proteomics : McP. 13: 1318-29. PMID 24627523 DOI: 10.1074/Mcp.O113.033571  0.434
2014 Rajagopala SV, Sikorski P, Kumar A, Mosca R, Vlasblom J, Arnold R, Franca-Koh J, Pakala SB, Phanse S, Ceol A, Häuser R, Siszler G, Wuchty S, Emili A, Babu M, ... Aloy P, et al. The binary protein-protein interaction landscape of Escherichia coli. Nature Biotechnology. 32: 285-90. PMID 24561554 DOI: 10.1038/Nbt.2831  0.453
2014 Arroyo R, Duran-Frigola M, Berenguer C, Soler-López M, Aloy P. Charting the molecular links between driver and susceptibility genes in colorectal cancer Biochemical and Biophysical Research Communications. 445: 734-738. PMID 24412244 DOI: 10.1016/J.Bbrc.2013.12.012  0.386
2014 Mosca R, Céol A, Stein A, Olivella R, Aloy P. 3did: a catalog of domain-based interactions of known three-dimensional structure. Nucleic Acids Research. 42: D374-9. PMID 24081580 DOI: 10.1093/Nar/Gkt887  0.413
2013 Mosca R, Pons T, Céol A, Valencia A, Aloy P. Towards a detailed atlas of protein-protein interactions. Current Opinion in Structural Biology. 23: 929-40. PMID 23896349 DOI: 10.1016/J.Sbi.2013.07.005  0.452
2013 Duran-Frigola M, Mosca R, Aloy P. Structural systems pharmacology: the role of 3D structures in next-generation drug development. Chemistry & Biology. 20: 674-84. PMID 23706634 DOI: 10.1016/J.Chembiol.2013.03.004  0.442
2013 Quiles F, Fernández-Rodríguez J, Mosca R, Feliubadaló L, Tornero E, Brunet J, Blanco I, Capellá G, Pujana MÀ, Aloy P, Monteiro A, Lázaro C. Functional and structural analysis of C-terminal BRCA1 missense variants. Plos One. 8: e61302. PMID 23613828 DOI: 10.1371/Journal.Pone.0061302  0.305
2013 Duran-Frigola M, Aloy P. Analysis of chemical and biological features yields mechanistic insights into drug side effects. Chemistry & Biology. 20: 594-603. PMID 23601648 DOI: 10.1016/J.Chembiol.2013.03.017  0.336
2013 Mosca R, Céol A, Aloy P. Interactome3D: adding structural details to protein networks. Nature Methods. 10: 47-53. PMID 23399932 DOI: 10.1038/Nmeth.2289  0.502
2012 Pache RA, Céol A, Aloy P. NetAligner--a network alignment server to compare complexes, pathways and whole interactomes. Nucleic Acids Research. 40: W157-61. PMID 22618871 DOI: 10.1093/Nar/Gks446  0.425
2012 Jaeger S, Aloy P. From protein interaction networks to novel therapeutic strategies Iubmb Life. 64: 529-537. PMID 22573601 DOI: 10.1002/Iub.1040  0.467
2012 Soler-López M, Badiola N, Zanzoni A, Aloy P. Towards Alzheimer's root cause: ECSIT as an integrating hub between oxidative stress, inflammation and mitochondrial dysfunction. Hypothetical role of the adapter protein ECSIT in familial and sporadic Alzheimer's disease pathogenesis. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 34: 532-41. PMID 22513506 DOI: 10.1002/Bies.201100193  0.691
2012 Mosca R, Pache RA, Aloy P. The role of structural disorder in the rewiring of protein interactions through evolution. Molecular & Cellular Proteomics : McP. 11: M111.014969. PMID 22389433 DOI: 10.1074/Mcp.M111.014969  0.448
2012 Pache RA, Aloy P. A novel framework for the comparative analysis of biological networks. Plos One. 7: e31220. PMID 22363585 DOI: 10.1371/Journal.Pone.0031220  0.421
2012 Duran-Frigola M, Aloy P. Recycling side-effects into clinical markers for drug repositioning. Genome Medicine. 4: 3. PMID 22283977 DOI: 10.1186/Gm302  0.3
2012 Belbin O, Coma M, Badiola N, Muñoz L, Suarez-Calvet M, Colom-Cadena M, Alcolea D, Clarimón J, Mas JM, Lleó A, Aloy P. Systems biology technology identifies presenilin-1–interacting proteins and drug targets that are novel to the Alzheimer's disease field Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.2148  0.35
2011 Stein A, Rueda M, Panjkovich A, Orozco M, Aloy P. A systematic study of the energetics involved in structural changes upon association and connectivity in protein interaction networks. Structure (London, England : 1993). 19: 881-9. PMID 21645858 DOI: 10.1016/J.Str.2011.03.009  0.395
2011 Feliu E, Aloy P, Oliva B. On the analysis of protein-protein interactions via knowledge-based potentials for the prediction of protein-protein docking. Protein Science : a Publication of the Protein Society. 20: 529-41. PMID 21432933 DOI: 10.1002/Pro.585  0.44
2011 Stein A, Mosca R, Aloy P. Three-dimensional modeling of protein interactions and complexes is going 'omics. Current Opinion in Structural Biology. 21: 200-8. PMID 21320770 DOI: 10.1016/J.Sbi.2011.01.005  0.467
2011 Soler-López M, Zanzoni A, Lluís R, Stelzl U, Aloy P. Interactome mapping suggests new mechanistic details underlying Alzheimer's disease. Genome Research. 21: 364-76. PMID 21163940 DOI: 10.1101/Gr.114280.110  0.705
2011 Stein A, Céol A, Aloy P. 3did: identification and classification of domain-based interactions of known three-dimensional structure. Nucleic Acids Research. 39: D718-23. PMID 20965963 DOI: 10.1093/Nar/Gkq962  0.354
2010 Brooks MA, Gewartowski K, Mitsiki E, Létoquart J, Pache RA, Billier Y, Bertero M, Corréa M, Czarnocki-Cieciura M, Dadlez M, Henriot V, Lazar N, Delbos L, Lebert D, Piwowarski J, ... ... Aloy P, et al. Systematic bioinformatics and experimental validation of yeast complexes reduces the rate of attrition during structural investigations. Structure (London, England : 1993). 18: 1075-82. PMID 20826334 DOI: 10.1016/J.Str.2010.08.001  0.325
2010 Stein A, Aloy P. Novel peptide-mediated interactions derived from high-resolution 3-dimensional structures. Plos Computational Biology. 6: e1000789. PMID 20502673 DOI: 10.1371/Journal.Pcbi.1000789  0.388
2010 Panjkovich A, Aloy P. Predicting protein-protein interaction specificity through the integration of three-dimensional structural information and the evolutionary record of protein domains. Molecular Biosystems. 6: 741-9. PMID 20237652 DOI: 10.1039/B918395G  0.456
2010 Pujol A, Mosca R, Farrés J, Aloy P. Unveiling the role of network and systems biology in drug discovery. Trends in Pharmacological Sciences. 31: 115-23. PMID 20117850 DOI: 10.1016/J.Tips.2009.11.006  0.423
2009 Aloy P, Oliva B. Splitting statistical potentials into meaningful scoring functions: testing the prediction of near-native structures from decoy conformations. Bmc Structural Biology. 9: 71. PMID 19917096 DOI: 10.1186/1472-6807-9-71  0.371
2009 Mosca R, Pons C, Fernández-Recio J, Aloy P. Pushing structural information into the yeast interactome by high-throughput protein docking experiments. Plos Computational Biology. 5: e1000490. PMID 19714207 DOI: 10.1371/Journal.Pcbi.1000490  0.453
2009 Stein A, Pache RA, Bernadó P, Pons M, Aloy P. Dynamic interactions of proteins in complex networks: a more structured view. The Febs Journal. 276: 5390-405. PMID 19712106 DOI: 10.1111/J.1742-4658.2009.07251.X  0.458
2009 Pache RA, Babu MM, Aloy P. Exploiting gene deletion fitness effects in yeast to understand the modular architecture of protein complexes under different growth conditions. Bmc Systems Biology. 3: 74. PMID 19615085 DOI: 10.1186/1752-0509-3-74  0.373
2009 Zanzoni A, Soler-López M, Aloy P. A network medicine approach to human disease. Febs Letters. 583: 1759-65. PMID 19269289 DOI: 10.1016/J.Febslet.2009.03.001  0.743
2009 Stein A, Panjkovich A, Aloy P. 3did Update: domain-domain and peptide-mediated interactions of known 3D structure. Nucleic Acids Research. 37: D300-4. PMID 18953040 DOI: 10.1093/Nar/Gkn690  0.38
2008 Russell RB, Aloy P. Targeting and tinkering with interaction networks. Nature Chemical Biology. 4: 666-73. PMID 18936751 DOI: 10.1038/Nchembio.119  0.384
2008 Parthasarathi L, Casey F, Stein A, Aloy P, Shields DC. Approved drug mimics of short peptide ligands from protein interaction motifs Journal of Chemical Information and Modeling. 48: 1943-1948. PMID 18826301 DOI: 10.1021/Ci800174C  0.39
2008 Stein A, Aloy P. Contextual specificity in peptide-mediated protein interactions. Plos One. 3: e2524. PMID 18596940 DOI: 10.1371/Journal.Pone.0002524  0.422
2008 Pache RA, Aloy P. Incorporating high-throughput proteomics experiments into structural biology pipelines: identification of the low-hanging fruits. Proteomics. 8: 1959-64. PMID 18491310 DOI: 10.1002/Pmic.200700966  0.406
2008 Aloy P, Russell R. Targeting and tinkering with interaction networks. Febs Letters. 582: 1219. PMID 18328822 DOI: 10.1016/J.Febslet.2008.02.069  0.384
2008 Pache RA, Zanzoni A, Naval J, Mas JM, Aloy P. Towards a molecular characterisation of pathological pathways. Febs Letters. 582: 1259-65. PMID 18282477 DOI: 10.1016/J.Febslet.2008.02.014  0.689
2008 Stein A, Aloy P. A molecular interpretation of genetic interactions in yeast. Febs Letters. 582: 1245-50. PMID 18282475 DOI: 10.1016/J.Febslet.2008.02.020  0.369
2007 Gavin A, Aloy P, Russell RB, Superti‐Furga G. Systems‐wide analysis of protein complexes in Saccharomyces cerevisiae The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A211-D  0.378
2006 Bravo J, Aloy P. Target selection for complex structural genomics. Current Opinion in Structural Biology. 16: 385-92. PMID 16713251 DOI: 10.1016/J.Sbi.2006.05.003  0.434
2006 Aloy P, Russell RB. Structural systems biology: modelling protein interactions. Nature Reviews. Molecular Cell Biology. 7: 188-97. PMID 16496021 DOI: 10.1038/Nrm1859  0.415
2006 Gavin AC, Aloy P, Grandi P, Krause R, Boesche M, Marzioch M, Rau C, Jensen LJ, Bastuck S, Dümpelfeld B, Edelmann A, Heurtier MA, Hoffman V, Hoefert C, Klein K, et al. Proteome survey reveals modularity of the yeast cell machinery. Nature. 440: 631-6. PMID 16429126 DOI: 10.1038/Nature04532  0.442
2005 Shah PK, Aloy P, Bork P, Russell RB. Structural similarity to bridge sequence space: finding new families on the bridges. Protein Science : a Publication of the Protein Society. 14: 1305-14. PMID 15840833 DOI: 10.1110/Ps.041187405  0.368
2005 Aloy P, Russell RB. Structure-based systems biology: a zoom lens for the cell. Febs Letters. 579: 1854-8. PMID 15763563 DOI: 10.1016/J.Febslet.2005.02.014  0.386
2005 Aloy P, Pichaud M, Russell RB. Protein complexes: structure prediction challenges for the 21st century. Current Opinion in Structural Biology. 15: 15-22. PMID 15718128 DOI: 10.1016/J.Sbi.2005.01.012  0.361
2005 Stein A, Russell RB, Aloy P. 3did: interacting protein domains of known three-dimensional structure. Nucleic Acids Research. 33: D413-7. PMID 15608228 DOI: 10.1093/Nar/Gki037  0.436
2004 Hothorn M, Wolf S, Aloy P, Greiner S, Scheffzek K. Structural insights into the target specificity of plant invertase and pectin methylesterase inhibitory proteins. The Plant Cell. 16: 3437-47. PMID 15528298 DOI: 10.1105/Tpc.104.025684  0.343
2004 Aloy P, Russell RB. Ten thousand interactions for the molecular biologist. Nature Biotechnology. 22: 1317-21. PMID 15470473 DOI: 10.1038/Nbt1018  0.419
2004 Russell RB, Alber F, Aloy P, Davis FP, Korkin D, Pichaud M, Topf M, Sali A. A structural perspective on protein-protein interactions. Current Opinion in Structural Biology. 14: 313-24. PMID 15193311 DOI: 10.1016/J.Sbi.2004.04.006  0.405
2004 Copley RR, Aloy P, Russell RB, Telford MJ. Systematic searches for molecular synapomorphies in model metazoan genomes give some support for Ecdysozoa after accounting for the idiosyncrasies of Caenorhabditis elegans. Evolution & Development. 6: 164-9. PMID 15099303 DOI: 10.1111/J.1525-142X.2004.04021.X  0.32
2004 Aloy P, Russell RB. Taking the mystery out of biological networks. Embo Reports. 5: 349-50. PMID 15060570 DOI: 10.1038/Sj.Embor.7400129  0.346
2004 Aloy P, Böttcher B, Ceulemans H, Leutwein C, Mellwig C, Fischer S, Gavin AC, Bork P, Superti-Furga G, Serrano L, Russell RB. Structure-based assembly of protein complexes in yeast. Science (New York, N.Y.). 303: 2026-9. PMID 15044803 DOI: 10.1126/Science.1092645  0.411
2003 Aloy P, Russell RB. Understanding and predicting protein assemblies with 3D structures. Comparative and Functional Genomics. 4: 410-5. PMID 18629088 DOI: 10.1002/Cfg.310  0.45
2003 Aloy P, Ceulemans H, Stark A, Russell RB. The relationship between sequence and interaction divergence in proteins. Journal of Molecular Biology. 332: 989-98. PMID 14499603 DOI: 10.1016/J.Jmb.2003.07.006  0.434
2003 Aloy P, Russell RB. InterPreTS: protein interaction prediction through tertiary structure. Bioinformatics (Oxford, England). 19: 161-2. PMID 12499311 DOI: 10.1093/Bioinformatics/19.1.161  0.416
2002 Aloy P, Russell RB. The third dimension for protein interactions and complexes. Trends in Biochemical Sciences. 27: 633-8. PMID 12468233 DOI: 10.1016/S0968-0004(02)02204-1  0.425
2002 Aloy P, Russell RB. Potential artefacts in protein-interaction networks. Febs Letters. 530: 253-4. PMID 12387902 DOI: 10.1016/S0014-5793(02)03427-0  0.435
2002 Torrents E, Aloy P, Gibert I, Rodríguez-Trelles F. Ribonucleotide reductases: divergent evolution of an ancient enzyme. Journal of Molecular Evolution. 55: 138-52. PMID 12107591 DOI: 10.1007/S00239-002-2311-7  0.311
2002 Aloy P, Russell RB. Interrogating protein interaction networks through structural biology. Proceedings of the National Academy of Sciences of the United States of America. 99: 5896-901. PMID 11972061 DOI: 10.1073/Pnas.092147999  0.456
2002 Aloy P, Oliva B, Querol E, Aviles FX, Russell RB. Structural similarity to link sequence space: new potential superfamilies and implications for structural genomics. Protein Science : a Publication of the Protein Society. 11: 1101-16. PMID 11967367 DOI: 10.1110/Ps.3950102  0.358
2001 Aloy P, Querol E, Aviles FX, Sternberg MJE. Automated structure-based prediction of functional sites in proteins: applications to assessing the validity of inheriting protein function from homology in genome annotation and to protein docking. Journal of Molecular Biology. 311: 395-408. PMID 11478868 DOI: 10.1006/Jmbi.2001.4870  0.379
2001 Mas JM, Aloy P, Martí-Renom MA, Oliva B, de Llorens R, Avilés FX, Querol E. Classification of protein disulphide-bridge topologies. Journal of Computer-Aided Molecular Design. 15: 477-87. PMID 11394740 DOI: 10.1023/A:1011164224144  0.371
2001 Aloy P, Companys V, Vendrell J, Aviles FX, Fricker LD, Coll M, Gomis-Rüth FX. The Crystal Structure of the Inhibitor-complexed Carboxypeptidase D Domain II and the Modeling of Regulatory Carboxypeptidases Journal of Biological Chemistry. 276: 16177-16184. PMID 11278909 DOI: 10.1074/Jbc.M011457200  0.323
1999 Aloy P, Moont G, Gabb HA, Querol E, Aviles FX, Sternberg MJ. Modelling repressor proteins docking to DNA. Proteins. 33: 535-49. PMID 9849937 DOI: 10.1002/(Sici)1097-0134(19981201)33:4<535::Aid-Prot6>3.0.Co;2-D  0.354
1999 Mas JM, Aloy P, Martí-Renom MA, Oliva B, Blanco-Aparicio C, Molina MA, de Llorens R, Querol E, Avilés FX. Protein similarities beyond disulphide bridge topology. Journal of Molecular Biology. 284: 541-8. PMID 9826496 DOI: 10.1006/Jmbi.1998.2194  0.398
1998 Aloy P, Catasús L, Villegas V, Reverter D, Vendrell J, Avilés FX. Comparative Analysis of the Sequences and Three-Dimensional Models of Human Procarboxypeptidases A1, A2 and B Biological Chemistry. 379: 149-156. PMID 9524066 DOI: 10.1515/Bchm.1998.379.2.149  0.304
1997 Aloy P, Cedano J, Oliva B, Avilés FX, Querol E. 'TransMem' : a neural network implemented in Excel spreadsheets for predicting transmembrane domains of proteins Bioinformatics. 13: 231-234. PMID 9183525 DOI: 10.1093/Bioinformatics/13.3.231  0.364
1997 Cedano J, Aloy P, Pérez-Pons JA, Querol E. Relation between amino acid composition and cellular location of proteins. Journal of Molecular Biology. 266: 594-600. PMID 9067612 DOI: 10.1006/Jmbi.1996.0804  0.376
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