| Year |
Citation |
Score |
| 2024 |
Mantica F, Iñiguez LP, Marquez Y, Permanyer J, Torres-Mendez A, Cruz J, Franch-Marro X, Tulenko F, Burguera D, Bertrand S, Doyle T, Nouzova M, Currie PD, Noriega FG, Escriva H, ... ... Irimia M, et al. Evolution of tissue-specific expression of ancestral genes across vertebrates and insects. Nature Ecology & Evolution. PMID 38622362 DOI: 10.1038/s41559-024-02398-5 |
0.343 |
|
| 2024 |
Arecco N, Mocavini I, Blanco E, Ballaré C, Libman E, Bonnal S, Irimia M, Di Croce L. Alternative splicing decouples local from global PRC2 activity. Molecular Cell. PMID 38452766 DOI: 10.1016/j.molcel.2024.02.011 |
0.773 |
|
| 2024 |
Yu D, Ren Y, Uesaka M, Beavan AJS, Muffato M, Shen J, Li Y, Sato I, Wan W, Clark JW, Keating JN, Carlisle EM, Dearden RP, Giles S, Randle E, ... ... Irimia M, et al. Hagfish genome elucidates vertebrate whole-genome duplication events and their evolutionary consequences. Nature Ecology & Evolution. PMID 38216617 DOI: 10.1038/s41559-023-02299-z |
0.638 |
|
| 2023 |
López-Oreja I, Gohr A, Playa-Albinyana H, Giró A, Arenas F, Higashi M, Tripathi R, López-Guerra M, Irimia M, Aymerich M, Valcárcel J, Bonnal S, Colomer D. mutation-mediated sensitization to H3B-8800 splicing inhibitor in chronic lymphocytic leukemia. Life Science Alliance. 6. PMID 37562845 DOI: 10.26508/lsa.202301955 |
0.578 |
|
| 2023 |
Pietroforte S, Barragan Monasterio M, Ferrer-Vaquer A, Irimia M, Ibáñez E, Popovic M, Vassena R, Zambelli F. Specific processing of meiosis-related transcript is linked to final maturation in human oocytes. Molecular Human Reproduction. 29. PMID 37261882 DOI: 10.1093/molehr/gaad021 |
0.325 |
|
| 2023 |
Gohr A, Iñiguez LP, Torres-Méndez A, Bonnal S, Irimia M. Insplico: effective computational tool for studying splicing order of adjacent introns genome-wide with short and long RNA-seq reads. Nucleic Acids Research. PMID 37026474 DOI: 10.1093/nar/gkad244 |
0.316 |
|
| 2023 |
Juan-Mateu J, Bajew S, Miret-Cuesta M, Íñiguez LP, Lopez-Pascual A, Bonnal S, Atla G, Bonàs-Guarch S, Ferrer J, Valcárcel J, Irimia M. Pancreatic microexons regulate islet function and glucose homeostasis. Nature Metabolism. PMID 36759540 DOI: 10.1038/s42255-022-00734-2 |
0.578 |
|
| 2022 |
Brasó-Vives M, Marlétaz F, Echchiki A, Mantica F, Acemel RD, Gómez-Skarmeta JL, Hartasánchez DA, Le Targa L, Pontarotti P, Tena JJ, Maeso I, Escriva H, Irimia M, Robinson-Rechavi M. Parallel evolution of amphioxus and vertebrate small-scale gene duplications. Genome Biology. 23: 243. PMID 36401278 DOI: 10.1186/s13059-022-02808-6 |
0.313 |
|
| 2022 |
Han H, Best AJ, Braunschweig U, Mikolajewicz N, Li JD, Roth J, Chowdhury F, Mantica F, Nabeel-Shah S, Parada G, Brown KR, O'Hanlon D, Wei J, Yao Y, Zid AA, ... ... Irimia M, et al. Systematic exploration of dynamic splicing networks reveals conserved multistage regulators of neurogenesis. Molecular Cell. PMID 35914530 DOI: 10.1016/j.molcel.2022.06.036 |
0.607 |
|
| 2022 |
Doyle T, Jimenez-Guri E, Hawkes WLS, Massy R, Mantica F, Permanyer J, Cozzuto L, Hermoso Pulido T, Baril T, Hayward A, Irimia M, Chapman JW, Bass C, Wotton KR. Genome-wide transcriptomic changes reveal the genetic pathways involved in insect migration. Molecular Ecology. PMID 35801824 DOI: 10.1111/mec.16588 |
0.319 |
|
| 2022 |
Spruce T, Plass M, Gohr A, Ray D, Martínez de Lagrán M, Rot G, Nóvoa A, Burguera D, Permanyer J, Miret M, Zheng H, Swanson MS, Morris Q, Mallo M, Dierssen M, ... ... Irimia M, et al. The X-linked splicing regulator MBNL3 has been co-opted to restrict placental growth in eutherians. Plos Biology. 20: e3001615. PMID 35476669 DOI: 10.1371/journal.pbio.3001615 |
0.334 |
|
| 2022 |
Wyatt CDR, Pernaute B, Gohr A, Miret-Cuesta M, Goyeneche L, Rovira Q, Salzer MC, Boke E, Bogdanovic O, Bonnal S, Irimia M. A developmentally programmed splicing failure contributes to DNA damage response attenuation during mammalian zygotic genome activation. Science Advances. 8: eabn4935. PMID 35417229 DOI: 10.1126/sciadv.abn4935 |
0.312 |
|
| 2022 |
Leon A, Subirana L, Magre K, Cases I, Tena JJ, Irimia M, Gomez-Skarmeta JL, Escriva H, Bertrand S. Gene regulatory networks of epidermal and neural fate choice in a chordate. Molecular Biology and Evolution. PMID 35276009 DOI: 10.1093/molbev/msac055 |
0.337 |
|
| 2022 |
Tammer L, Hameiri O, Keydar I, Roy VR, Ashkenazy-Titelman A, Custódio N, Sason I, Shayevitch R, Rodríguez-Vaello V, Rino J, Lev Maor G, Leader Y, Khair D, Aiden EL, Elkon R, ... Irimia M, et al. Gene architecture directs splicing outcome in separate nuclear spatial regions. Molecular Cell. PMID 35182478 DOI: 10.1016/j.molcel.2022.02.001 |
0.346 |
|
| 2021 |
Márquez Y, Mantica F, Cozzuto L, Burguera D, Hermoso-Pulido A, Ponomarenko J, Roy SW, Irimia M. ExOrthist: a tool to infer exon orthologies at any evolutionary distance. Genome Biology. 22: 239. PMID 34416914 DOI: 10.1186/s13059-021-02441-9 |
0.367 |
|
| 2021 |
Espeso-Gil S, Holik AZ, Bonnin S, Jhanwar S, Chandrasekaran S, Pique-Regi R, Albaigès-Ràfols J, Maher M, Permanyer J, Irimia M, Friedländer MR, Pons-Espinal M, Akbarian S, Dierssen M, Maass PG, et al. Environmental Enrichment Induces Epigenomic and Genome Organization Changes Relevant for Cognition. Frontiers in Molecular Neuroscience. 14: 664912. PMID 34025350 DOI: 10.3389/fnmol.2021.664912 |
0.302 |
|
| 2020 |
Almudi I, Vizueta J, Wyatt CDR, de Mendoza A, Marlétaz F, Firbas PN, Feuda R, Masiero G, Medina P, Alcaina-Caro A, Cruz F, Gómez-Garrido J, Gut M, Alioto TS, Vargas-Chavez C, ... ... Irimia M, et al. Genomic adaptations to aquatic and aerial life in mayflies and the origin of insect wings. Nature Communications. 11: 2631. PMID 32457347 DOI: 10.1038/S41467-020-16284-8 |
0.348 |
|
| 2020 |
Touceda-Suárez M, Kita EM, Acemel RD, Firbas PN, Magri MS, Naranjo S, Tena JJ, Gómez-Skarmeta JL, Maeso I, Irimia M. Ancient genomic regulatory blocks are a source for regulatory gene deserts in vertebrates after whole genome duplications. Molecular Biology and Evolution. PMID 32421818 DOI: 10.1093/molbev/msaa123 |
0.406 |
|
| 2020 |
Gonatopoulos-Pournatzis T, Niibori R, Salter EW, Weatheritt RJ, Tsang B, Farhangmehr S, Liang X, Braunschweig U, Roth J, Zhang S, Henderson T, Sharma E, Quesnel-Vallières M, Permanyer J, Maier S, ... ... Irimia M, et al. Autism-Misregulated eIF4G Microexons Control Synaptic Translation and Higher Order Cognitive Functions. Molecular Cell. PMID 31999954 DOI: 10.1016/J.Molcel.2020.01.006 |
0.533 |
|
| 2019 |
Capponi S, Stöffler N, Irimia M, Van Schaik FMA, Ondik MM, Biniossek ML, Lehmann L, Mitschke J, Vermunt MW, Creyghton MP, Graybiel AM, Reinheckel T, Schilling O, Blencowe BJ, Crittenden JR, et al. Neuronal-specific microexon splicing of mRNA is directly regulated by SRRM4/nSR100. Rna Biology. 1-13. PMID 31559909 DOI: 10.1080/15476286.2019.1667214 |
0.532 |
|
| 2019 |
Torres-Méndez A, Bonnal S, Marquez Y, Roth J, Iglesias M, Permanyer J, Almudí I, O'Hanlon D, Guitart T, Soller M, Gingras AC, Gebauer F, Rentzsch F, Blencowe BJ, Valcárcel J, ... Irimia M, et al. A novel protein domain in an ancestral splicing factor drove the evolution of neural microexons. Nature Ecology & Evolution. PMID 30833759 DOI: 10.1038/S41559-019-0813-6 |
0.743 |
|
| 2019 |
Magomedova L, Tiefenbach J, Zilberman E, Le Billan F, Voisin V, Saikali M, Boivin V, Robitaille M, Gueroussov S, Irimia M, Ray D, Patel R, Xu C, Jeyasuria P, Bader GD, et al. ARGLU1 is a transcriptional coactivator and splicing regulator important for stress hormone signaling and development. Nucleic Acids Research. PMID 30698747 DOI: 10.1093/Nar/Gkz010 |
0.598 |
|
| 2018 |
Marlétaz F, Firbas PN, Maeso I, Tena JJ, Bogdanovic O, Perry M, Wyatt CDR, de la Calle-Mustienes E, Bertrand S, Burguera D, Acemel RD, van Heeringen SJ, Naranjo S, Herrera-Ubeda C, Skvortsova K, ... ... Irimia M, et al. Amphioxus functional genomics and the origins of vertebrate gene regulation. Nature. PMID 30464347 DOI: 10.1038/S41586-018-0734-6 |
0.752 |
|
| 2018 |
Parikshak NN, Swarup V, Belgard TG, Irimia M, Ramaswami G, Gandal MJ, Hartl C, Leppa V, de la Torre Ubieta L, Huang J, Lowe JK, Blencowe BJ, Horvath S, Geschwind DH. Author Correction: Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism. Nature. PMID 29995847 DOI: 10.1038/S41586-018-0295-8 |
0.554 |
|
| 2018 |
Fernandez JP, Moreno-Mateos MA, Gohr A, Miao L, Chan SH, Irimia M, Giraldez AJ. RES complex is associated with intron definition and required for zebrafish early embryogenesis. Plos Genetics. 14: e1007473. PMID 29969449 DOI: 10.1371/journal.pgen.1007473 |
0.349 |
|
| 2017 |
Albuixech-Crespo B, Herrera-Úbeda C, Marfany G, Irimia M, Garcia-Fernàndez J. Origin and evolution of the chordate central nervous system: insights from amphioxus genoarchitecture. The International Journal of Developmental Biology. 61: 655-664. PMID 29319114 DOI: 10.1387/ijdb.170258jg |
0.775 |
|
| 2017 |
Vigevani L, Gohr A, Webb T, Irimia M, Valcárcel J. Molecular basis of differential 3' splice site sensitivity to anti-tumor drugs targeting U2 snRNP. Nature Communications. 8: 2100. PMID 29235465 DOI: 10.1038/S41467-017-02007-Z |
0.582 |
|
| 2017 |
Burguera D, Marquez Y, Racioppi C, Permanyer J, Torres-Méndez A, Esposito R, Albuixech-Crespo B, Fanlo L, D'Agostino Y, Gohr A, Navas-Perez E, Riesgo A, Cuomo C, Benvenuto G, Christiaen LA, ... ... Irimia M, et al. Evolutionary recruitment of flexible Esrp-dependent splicing programs into diverse embryonic morphogenetic processes. Nature Communications. 8: 1799. PMID 29180615 DOI: 10.1038/S41467-017-01961-Y |
0.756 |
|
| 2017 |
Tapial J, Ha KCH, Sterne-Weiler T, Gohr A, Braunschweig U, Hermoso-Pulido A, Quesnel-Vallières M, Permanyer J, Sodaei R, Marquez Y, Cozzuto L, Wang X, Gómez-Velázquez M, Rayon T, Manzanares M, ... ... Irimia M, et al. An atlas of alternative splicing profiles and functional associations reveals new regulatory programs and genes that simultaneously express multiple major isoforms. Genome Research. PMID 28855263 DOI: 10.1101/Gr.220962.117 |
0.658 |
|
| 2017 |
Albuixech-Crespo B, López-Blanch L, Burguera D, Maeso I, Sánchez-Arrones L, Moreno-Bravo JA, Somorjai I, Pascual-Anaya J, Puelles E, Bovolenta P, Garcia-Fernàndez J, Puelles L, Irimia M, Ferran JL. Molecular regionalization of the developing amphioxus neural tube challenges major partitions of the vertebrate brain. Plos Biology. 15: e2001573. PMID 28422959 DOI: 10.1371/Journal.Pbio.2001573 |
0.793 |
|
| 2017 |
Muñoz MJ, Nieto Moreno N, Giono LE, Cambindo Botto AE, Dujardin G, Bastianello G, Lavore S, Torres-Méndez A, Menck CF, Blencowe BJ, Irimia M, Foiani M, Kornblihtt AR. Major Roles for Pyrimidine Dimers, Nucleotide Excision Repair, and ATR in the Alternative Splicing Response to UV Irradiation. Cell Reports. 18: 2868-2879. PMID 28329680 DOI: 10.1016/J.Celrep.2017.02.066 |
0.471 |
|
| 2016 |
Quesnel-Vallières M, Dargaei Z, Irimia M, Gonatopoulos-Pournatzis T, Ip JY, Wu M, Sterne-Weiler T, Nakagawa S, Woodin MA, Blencowe BJ, Cordes SP. Misregulation of an Activity-Dependent Splicing Network as a Common Mechanism Underlying Autism Spectrum Disorders. Molecular Cell. 64: 1023-1034. PMID 27984743 DOI: 10.1016/J.Molcel.2016.11.033 |
0.544 |
|
| 2016 |
Parikshak NN, Swarup V, Belgard TG, Irimia M, Ramaswami G, Gandal MJ, Hartl C, Leppa V, Ubieta LT, Huang J, Lowe JK, Blencowe BJ, Horvath S, Geschwind DH. Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism. Nature. PMID 27919067 DOI: 10.1038/Nature20612 |
0.601 |
|
| 2016 |
Martin S, Bellora N, González-Vallinas J, Irimia M, Chebli K, DeToledo M, Raabe M, Eyras E, Urlaub H, Blencowe BJ, Tazi J. Preferential Binding of a stable G3BP Ribonucleoprotein Complex to Intron-retaining Transcripts in Mouse Brain and Modulation of their Expression in the Cerebellum. Journal of Neurochemistry. PMID 27513819 DOI: 10.1111/jnc.13768 |
0.313 |
|
| 2016 |
Solana J, Irimia M, Ayoub S, Orejuela MR, Zywitza V, Jens M, Tapial J, Ray D, Morris Q, Hughes TR, Blencowe BJ, Rajewsky N. Conserved functional antagonism of CELF and MBNL proteins controls stem cell-specific alternative splicing in planarians. Elife. 5. PMID 27502555 DOI: 10.7554/eLife.16797 |
0.561 |
|
| 2016 |
Maeso I, Dunwell TL, Wyatt CD, Marlétaz F, Vető B, Bernal JA, Quah S, Irimia M, Holland PW. Evolutionary origin and functional divergence of totipotent cell homeobox genes in eutherian mammals. Bmc Biology. 14: 45. PMID 27296695 DOI: 10.1186/S12915-016-0267-0 |
0.623 |
|
| 2015 |
de Mendoza A, Suga H, Permanyer J, Irimia M, Ruiz-Trillo I. Complex transcriptional regulation and independent evolution of fungal-like traits in a relative of animals. Elife. 4. PMID 26465111 DOI: 10.7554/Elife.08904 |
0.352 |
|
| 2015 |
Giampietro C, Deflorian G, Gallo S, Di Matteo A, Pradella D, Bonomi S, Belloni E, Nyqvist D, Quaranta V, Confalonieri S, Bertalot G, Orsenigo F, Pisati F, Ferrero E, Biamonti G, ... ... Irimia M, et al. The alternative splicing factor Nova2 regulates vascular development and lumen formation. Nature Communications. 6: 8479. PMID 26446569 DOI: 10.1038/Ncomms9479 |
0.541 |
|
| 2015 |
Gueroussov S, Gonatopoulos-Pournatzis T, Irimia M, Raj B, Lin ZY, Gingras AC, Blencowe BJ. RNA SPLICING. An alternative splicing event amplifies evolutionary differences between vertebrates. Science (New York, N.Y.). 349: 868-73. PMID 26293963 DOI: 10.1126/Science.Aaa8381 |
0.6 |
|
| 2015 |
Quesnel-Vallières M, Irimia M, Cordes SP, Blencowe BJ. Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development. Genes & Development. 29: 746-59. PMID 25838543 DOI: 10.1101/gad.256115.114 |
0.597 |
|
| 2014 |
Irimia M, Weatheritt RJ, Ellis JD, Parikshak NN, Gonatopoulos-Pournatzis T, Babor M, Quesnel-Vallières M, Tapial J, Raj B, O'Hanlon D, Barrios-Rodiles M, Sternberg MJ, Cordes SP, Roth FP, Wrana JL, et al. A highly conserved program of neuronal microexons is misregulated in autistic brains. Cell. 159: 1511-23. PMID 25525873 DOI: 10.1016/J.Cell.2014.11.035 |
0.596 |
|
| 2014 |
Braunschweig U, Barbosa-Morais NL, Pan Q, Nachman EN, Alipanahi B, Gonatopoulos-Pournatzis T, Frey B, Irimia M, Blencowe BJ. Widespread intron retention in mammals functionally tunes transcriptomes. Genome Research. 24: 1774-86. PMID 25258385 DOI: 10.1101/Gr.177790.114 |
0.576 |
|
| 2014 |
Raj B, Irimia M, Braunschweig U, Sterne-Weiler T, O'Hanlon D, Lin ZY, Chen GI, Easton LE, Ule J, Gingras AC, Eyras E, Blencowe BJ. A global regulatory mechanism for activating an exon network required for neurogenesis. Molecular Cell. 56: 90-103. PMID 25219497 DOI: 10.1016/J.Molcel.2014.08.011 |
0.595 |
|
| 2014 |
Irimia M, Roy SW. Origin of spliceosomal introns and alternative splicing. Cold Spring Harbor Perspectives in Biology. 6. PMID 24890509 DOI: 10.1101/Cshperspect.A016071 |
0.321 |
|
| 2014 |
Katsani KR, Irimia M, Karapiperis C, Scouras ZG, Blencowe BJ, Promponas VJ, Ouzounis CA. Functional genomics evidence unearths new moonlighting roles of outer ring coat nucleoporins. Scientific Reports. 4: 4655. PMID 24722254 DOI: 10.1038/srep04655 |
0.594 |
|
| 2014 |
Roy SW, Irimia M. Diversity and evolution of spliceosomal systems. Methods in Molecular Biology (Clifton, N.J.). 1126: 13-33. PMID 24549653 DOI: 10.1007/978-1-62703-980-2_2 |
0.387 |
|
| 2013 |
Sebé-Pedrós A, Irimia M, Del Campo J, Parra-Acero H, Russ C, Nusbaum C, Blencowe BJ, Ruiz-Trillo I. Regulated aggregative multicellularity in a close unicellular relative of metazoa. Elife. 2: e01287. PMID 24368732 DOI: 10.7554/Elife.01287 |
0.564 |
|
| 2013 |
Maeso I, Irimia M, Tena JJ, Casares F, Gómez-Skarmeta JL. Deep conservation of cis-regulatory elements in metazoans. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 368: 20130020. PMID 24218633 DOI: 10.1098/rstb.2013.0020 |
0.358 |
|
| 2013 |
Venables JP, Lapasset L, Gadea G, Fort P, Klinck R, Irimia M, Vignal E, Thibault P, Prinos P, Chabot B, Abou Elela S, Roux P, Lemaitre JM, Tazi J. MBNL1 and RBFOX2 cooperate to establish a splicing programme involved in pluripotent stem cell differentiation. Nature Communications. 4: 2480. PMID 24048253 DOI: 10.1038/Ncomms3480 |
0.322 |
|
| 2013 |
Ray D, Kazan H, Cook KB, Weirauch MT, Najafabadi HS, Li X, Gueroussov S, Albu M, Zheng H, Yang A, Na H, Irimia M, Matzat LH, Dale RK, Smith SA, et al. A compendium of RNA-binding motifs for decoding gene regulation. Nature. 499: 172-7. PMID 23846655 DOI: 10.1038/Nature12311 |
0.545 |
|
| 2013 |
Irimia M, Maeso I, Roy SW, Fraser HB. Ancient cis-regulatory constraints and the evolution of genome architecture. Trends in Genetics : Tig. 29: 521-8. PMID 23791467 DOI: 10.1016/J.Tig.2013.05.008 |
0.678 |
|
| 2013 |
Han H, Irimia M, Ross PJ, Sung HK, Alipanahi B, David L, Golipour A, Gabut M, Michael IP, Nachman EN, Wang E, Trcka D, Thompson T, O'Hanlon D, Slobodeniuc V, et al. MBNL proteins repress ES-cell-specific alternative splicing and reprogramming. Nature. 498: 241-5. PMID 23739326 DOI: 10.1038/Nature12270 |
0.596 |
|
| 2013 |
Colak R, Kim T, Michaut M, Sun M, Irimia M, Bellay J, Myers CL, Blencowe BJ, Kim PM. Distinct types of disorder in the human proteome: functional implications for alternative splicing. Plos Computational Biology. 9: e1003030. PMID 23633940 DOI: 10.1371/Journal.Pcbi.1003030 |
0.53 |
|
| 2013 |
Clarke M, Lohan AJ, Liu B, Lagkouvardos I, Roy S, Zafar N, Bertelli C, Schilde C, Kianianmomeni A, Bürglin TR, Frech C, Turcotte B, Kopec KO, Synnott JM, Choo C, ... ... Irimia M, et al. Genome of Acanthamoeba castellanii highlights extensive lateral gene transfer and early evolution of tyrosine kinase signaling. Genome Biology. 14: R11. PMID 23375108 DOI: 10.1186/Gb-2013-14-2-R11 |
0.324 |
|
| 2013 |
Cañestro C, Albalat R, Irimia M, Garcia-Fernàndez J. Impact of gene gains, losses and duplication modes on the origin and diversification of vertebrates Seminars in Cell and Developmental Biology. 24: 83-94. PMID 23291262 DOI: 10.1016/J.Semcdb.2012.12.008 |
0.677 |
|
| 2012 |
Barbosa-Morais NL, Irimia M, Pan Q, Xiong HY, Gueroussov S, Lee LJ, Slobodeniuc V, Kutter C, Watt S, Colak R, Kim T, Misquitta-Ali CM, Wilson MD, Kim PM, Odom DT, et al. The evolutionary landscape of alternative splicing in vertebrate species. Science (New York, N.Y.). 338: 1587-93. PMID 23258890 DOI: 10.1126/Science.1230612 |
0.579 |
|
| 2012 |
Ariza-Cosano A, Visel A, Pennacchio LA, Fraser HB, Gómez-Skarmeta JL, Irimia M, Bessa J. Differences in enhancer activity in mouse and zebrafish reporter assays are often associated with changes in gene expression. Bmc Genomics. 13: 713. PMID 23253453 DOI: 10.1186/1471-2164-13-713 |
0.636 |
|
| 2012 |
Curtis BA, Tanifuji G, Burki F, Gruber A, Irimia M, Maruyama S, Arias MC, Ball SG, Gile GH, Hirakawa Y, Hopkins JF, Kuo A, Rensing SA, Schmutz J, Symeonidi A, et al. Algal genomes reveal evolutionary mosaicism and the fate of nucleomorphs. Nature. 492: 59-65. PMID 23201678 DOI: 10.1038/Nature11681 |
0.332 |
|
| 2012 |
Khare T, Pai S, Koncevicius K, Pal M, Kriukiene E, Liutkeviciute Z, Irimia M, Jia P, Ptak C, Xia M, Tice R, Tochigi M, Moréra S, Nazarians A, Belsham D, et al. 5-hmC in the brain is abundant in synaptic genes and shows differences at the exon-intron boundary. Nature Structural & Molecular Biology. 19: 1037-43. PMID 22961382 DOI: 10.1038/Nsmb.2372 |
0.577 |
|
| 2012 |
Ellis JD, Barrios-Rodiles M, Colak R, Irimia M, Kim T, Calarco JA, Wang X, Pan Q, O'Hanlon D, Kim PM, Wrana JL, Blencowe BJ. Tissue-specific alternative splicing remodels protein-protein interaction networks. Molecular Cell. 46: 884-92. PMID 22749401 DOI: 10.1016/J.Molcel.2012.05.037 |
0.743 |
|
| 2012 |
Irimia M, Tena JJ, Alexis MS, Fernandez-Miñan A, Maeso I, Bogdanovic O, de la Calle-Mustienes E, Roy SW, Gómez-Skarmeta JL, Fraser HB. Extensive conservation of ancient microsynteny across metazoans due to cis-regulatory constraints. Genome Research. 22: 2356-67. PMID 22722344 DOI: 10.1101/Gr.139725.112 |
0.699 |
|
| 2012 |
Labbé RM, Irimia M, Currie KW, Lin A, Zhu SJ, Brown DD, Ross EJ, Voisin V, Bader GD, Blencowe BJ, Pearson BJ. A comparative transcriptomic analysis reveals conserved features of stem cell pluripotency in planarians and mammals. Stem Cells (Dayton, Ohio). 30: 1734-45. PMID 22696458 DOI: 10.1002/Stem.1144 |
0.537 |
|
| 2012 |
Irimia M, Royo JL, Burguera D, Maeso I, Gómez-Skarmeta JL, Garcia-Fernandez J. Comparative genomics of the Hedgehog loci in chordates and the origins of Shh regulatory novelties Scientific Reports. 2. PMID 22666536 DOI: 10.1038/Srep00433 |
0.624 |
|
| 2012 |
Irimia M, Blencowe BJ. Alternative splicing: decoding an expansive regulatory layer. Current Opinion in Cell Biology. 24: 323-32. PMID 22465326 DOI: 10.1016/j.ceb.2012.03.005 |
0.613 |
|
| 2012 |
Irimia M, Denuc A, Ferran JL, Pernaute B, Puelles L, Roy SW, Garcia-Fernà ndez J, Marfany G. Evolutionarily conserved A-to-I editing increases protein stability of the alternative splicing factor Nova1. Rna Biology. 9: 12-21. PMID 22258141 DOI: 10.4161/Rna.9.1.18387 |
0.636 |
|
| 2012 |
Maeso I, Irimia M, Tena JJ, González-Pérez E, Tran D, Ravi V, Venkatesh B, Campuzano S, Gómez-Skarmeta JL, Garcia-Fernàndez J. An ancient genomic regulatory block conserved across bilaterians and its dismantling in tetrapods by retrogene replacement Genome Research. 22: 642-655. PMID 22234889 DOI: 10.1101/Gr.132233.111 |
0.587 |
|
| 2011 |
Royo JL, Maeso I, Irimia M, Gao F, Peter IS, Lopes CS, D'Aniello S, Casares F, Davidson EH, Garcia-Fernández J, Gómez-Skarmeta JL. Transphyletic conservation of developmental regulatory state in animal evolution. Proceedings of the National Academy of Sciences of the United States of America. 108: 14186-91. PMID 21844364 DOI: 10.1073/Pnas.1109037108 |
0.762 |
|
| 2011 |
Irimia M, Maeso I, Burguera D, Hidalgo-Sánchez M, Puelles L, Roy SW, Garcia-Fernà ndez J, Ferran JL. Contrasting 5' and 3' evolutionary histories and frequent evolutionary convergence in Meis/hth gene structures. Genome Biology and Evolution. 3: 551-64. PMID 21680890 DOI: 10.1093/Gbe/Evr056 |
0.695 |
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| 2011 |
Sánchez-Guardado LÓ, Irimia M, Sánchez-Arrones L, Burguera D, RodrÃguez-Gallardo L, Garcia-Fernández J, Puelles L, Ferran JL, Hidalgo-Sánchez M. Distinct and redundant expression and transcriptional diversity of MEIS gene paralogs during chicken development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 240: 1475-92. PMID 21465619 DOI: 10.1002/Dvdy.22621 |
0.677 |
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| 2011 |
Irimia M, Denuc A, Burguera D, Somorjai I, MartÃn-Durán JM, Genikhovich G, Jimenez-Delgado S, Technau U, Roy SW, Marfany G, Garcia-Fernà ndez J. Stepwise assembly of the Nova-regulated alternative splicing network in the vertebrate brain. Proceedings of the National Academy of Sciences of the United States of America. 108: 5319-24. PMID 21389270 DOI: 10.1073/Pnas.1012333108 |
0.801 |
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| 2010 |
Irimia M, Piñeiro C, Maeso I, Gómez-Skarmeta JL, Casares F, Garcia-Fernàndez J. Conserved developmental expression of Fezf in chordates and Drosophila and the origin of the Zona Limitans Intrathalamica (ZLI) brain organizer. Evodevo. 1: 7. PMID 20849572 DOI: 10.1186/2041-9139-1-7 |
0.648 |
|
| 2010 |
Irimia M, Maeso I, Gunning PW, Garcia-Fernàndez J, Roy SW. Internal and external paralogy in the evolution of tropomyosin genes in metazoans. Molecular Biology and Evolution. 27: 1504-17. PMID 20147436 DOI: 10.1093/Molbev/Msq018 |
0.688 |
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| 2009 |
Irimia M, Roy SW, Neafsey DE, Abril JF, Garcia-Fernandez J, Koonin EV. Complex selection on 5' splice sites in intron-rich organisms. Genome Research. 19: 2021-7. PMID 19745111 DOI: 10.1101/Gr.089276.108 |
0.625 |
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| 2009 |
Roy SW, Irimia M. Splicing in the eukaryotic ancestor: form, function and dysfunction. Trends in Ecology & Evolution. 24: 447-55. PMID 19576657 DOI: 10.1016/J.Tree.2009.04.005 |
0.415 |
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| 2009 |
Garcia-Fernà ndez J, Jiménez-Delgado S, Pascual-Anaya J, Maeso I, Irimia M, Minguillón C, Benito-Gutiérrez E, Gardenyes J, Bertrand S, D'Aniello S. From the American to the European amphioxus: towards experimental Evo-Devo at the origin of chordates. The International Journal of Developmental Biology. 53: 1359-66. PMID 19247934 DOI: 10.1387/Ijdb.072436Jg |
0.736 |
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| 2009 |
Irimia M, Rukov JL, Roy SW, Vinther J, Garcia-Fernandez J. Quantitative regulation of alternative splicing in evolution and development. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 31: 40-50. PMID 19154001 DOI: 10.1002/Bies.080092 |
0.692 |
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| 2008 |
Irimia M, Roy SW. Evolutionary convergence on highly-conserved 3' intron structures in intron-poor eukaryotes and insights into the ancestral eukaryotic genome. Plos Genetics. 4: e1000148. PMID 18688272 DOI: 10.1371/Journal.Pgen.1000148 |
0.35 |
|
| 2008 |
Irimia M, Rukov JL, Penny D, Vinther J, Garcia-Fernandez J, Roy SW. Origin of introns by 'intronization' of exonic sequences. Trends in Genetics : Tig. 24: 378-81. PMID 18597887 DOI: 10.1016/J.Tig.2008.05.007 |
0.623 |
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| 2008 |
D'Aniello S, Irimia M, Maeso I, Pascual-Anaya J, Jiménez-Delgado S, Bertrand S, Garcia-Fernà ndez J. Gene expansion and retention leads to a diverse tyrosine kinase superfamily in amphioxus. Molecular Biology and Evolution. 25: 1841-54. PMID 18550616 DOI: 10.1093/Molbev/Msn132 |
0.758 |
|
| 2008 |
Roy SW, Irimia M. When good transcripts go bad: artifactual RT-PCR 'splicing' and genome analysis. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 30: 601-5. PMID 18478540 DOI: 10.1002/Bies.20749 |
0.353 |
|
| 2008 |
Irimia M, Maeso I, Garcia-Fernàndez J. Convergent evolution of clustering of Iroquois homeobox genes across metazoans. Molecular Biology and Evolution. 25: 1521-5. PMID 18469332 DOI: 10.1093/Molbev/Msn109 |
0.632 |
|
| 2008 |
Irimia M, Rukov JL, Penny D, Garcia-Fernandez J, Vinther J, Roy SW. Widespread evolutionary conservation of alternatively spliced exons in Caenorhabditis. Molecular Biology and Evolution. 25: 375-82. PMID 18048400 DOI: 10.1093/Molbev/Msm262 |
0.669 |
|
| 2007 |
Irimia M, Rukov JL, Penny D, Roy SW. Functional and evolutionary analysis of alternatively spliced genes is consistent with an early eukaryotic origin of alternative splicing. Bmc Evolutionary Biology. 7: 188. PMID 17916237 DOI: 10.1186/1471-2148-7-188 |
0.372 |
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| 2007 |
Irimia M, Maeso I, Penny D, Garcia-Fernàndez J, Roy SW. Rare coding sequence changes are consistent with Ecdysozoa, not Coelomata. Molecular Biology and Evolution. 24: 1604-7. PMID 17525471 DOI: 10.1093/Molbev/Msm105 |
0.599 |
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| 2007 |
Rukov JL, Irimia M, Mørk S, Lund VK, Vinther J, Arctander P. High qualitative and quantitative conservation of alternative splicing in Caenorhabditis elegans and Caenorhabditis briggsae. Molecular Biology and Evolution. 24: 909-17. PMID 17272679 DOI: 10.1093/molbev/msm023 |
0.397 |
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