| Year |
Citation |
Score |
| 2023 |
Parsons NB, Annamalai B, Rohrer B. Regulatable Complement Inhibition of the Alternative Pathway Mitigates Wet Age-Related Macular Degeneration Pathology in a Mouse Model. Translational Vision Science & Technology. 12: 17. PMID 37462980 DOI: 10.1167/tvst.12.7.17 |
0.658 |
|
| 2023 |
Rohrer B, Parsons N, Annamalai B, Nicholson C, Obert E, Jones B, Dick AD. Elastin Layer in Bruch's Membrane as a Target for Immunization or Tolerization to Modulate Pathology in the Mouse Model of Smoke-Induced Ocular Injury. Advances in Experimental Medicine and Biology. 1415: 67-71. PMID 37440016 DOI: 10.1007/978-3-031-27681-1_11 |
0.705 |
|
| 2023 |
Ishii M, Rohrer B. Anaphylatoxin C5a receptor signaling induces mitochondrial fusion and sensitizes retina pigment epithelial cells to oxidative stress. Biochimica Et Biophysica Acta. General Subjects. 130374. PMID 37187450 DOI: 10.1016/j.bbagen.2023.130374 |
0.449 |
|
| 2023 |
Navneet S, Brandon C, Simpson K, Rohrer B. Exploring the Therapeutic Potential of Elastase Inhibition in Age-Related Macular Degeneration in Mouse and Human. Cells. 12. PMID 37174708 DOI: 10.3390/cells12091308 |
0.367 |
|
| 2022 |
Navneet S, Rohrer B. Elastin turnover in ocular diseases: A special focus on age-related macular degeneration. Experimental Eye Research. 222: 109164. PMID 35798060 DOI: 10.1016/j.exer.2022.109164 |
0.31 |
|
| 2022 |
Akter T, Annamalai B, Obert E, Simpson KN, Rohrer B. Dabigatran and Wet AMD, Results From Retinal Pigment Epithelial Cell Monolayers, the Mouse Model of Choroidal Neovascularization, and Patients From the Medicare Data Base. Frontiers in Immunology. 13: 896274. PMID 35784301 DOI: 10.3389/fimmu.2022.896274 |
0.801 |
|
| 2021 |
Rohrer B, Parsons N, Annamalai B, Nicholson C, Obert E, Jones B, Dick AD. Peptide-based immunotherapy against oxidized elastin ameliorates pathology in mouse model of smoke-induced ocular injury. Experimental Eye Research. 108755. PMID 34487725 DOI: 10.1016/j.exer.2021.108755 |
0.688 |
|
| 2021 |
Ishii M, Beeson G, Beeson C, Rohrer B. Isolation of Mitochondria from Retinal Pigment Epithelial Cell Cultures and an Application of High-Resolution Respirometric Assay (XF96 Seahorse Assay). Methods in Molecular Biology (Clifton, N.J.). 2277: 423-431. PMID 34080166 DOI: 10.1007/978-1-0716-1270-5_26 |
0.617 |
|
| 2021 |
Rohrer B, Biswal MR, Obert E, Dang Y, Su Y, Zuo X, Fogelgren B, Kondkar AA, Lobo GP, Lipschutz JH. Conditional Loss of the Exocyst Component Exoc5 in Retinal Pigment Epithelium (RPE) Results in RPE Dysfunction, Photoreceptor Cell Degeneration, and Decreased Visual Function. International Journal of Molecular Sciences. 22. PMID 34064901 DOI: 10.3390/ijms22105083 |
0.304 |
|
| 2021 |
Beeson C, Peterson YK, Perron N, Bandyopadhyay M, Nasarre C, Beeson G, Comer RF, Lindsey CC, Schnellmann RG, Rohrer B. Newly Identified Chemicals Preserve Mitochondrial Capacity and Decelerate Loss of Photoreceptor Cells in Murine Retinal Degeneration Models. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. PMID 33945330 DOI: 10.1089/jop.2020.0140 |
0.627 |
|
| 2021 |
Annamalai B, Parsons N, Nicholson C, Joseph K, Coughlin B, Yang X, Jones BW, Tomlinson S, Rohrer B. Natural immunoglobulin M-based delivery of a complement alternative pathway inhibitor in mouse models of retinal degeneration. Experimental Eye Research. 108583. PMID 33878326 DOI: 10.1016/j.exer.2021.108583 |
0.823 |
|
| 2021 |
Annamalai B, Parsons N, Nicholson C, Obert E, Jones B, Rohrer B. Subretinal Rather Than Intravitreal Adeno-Associated Virus-Mediated Delivery of a Complement Alternative Pathway Inhibitor Is Effective in a Mouse Model of RPE Damage. Investigative Ophthalmology & Visual Science. 62: 11. PMID 33830174 DOI: 10.1167/iovs.62.4.11 |
0.814 |
|
| 2021 |
Ishii M, Beeson G, Beeson C, Rohrer B. Mitochondrial C3a Receptor Activation in Oxidatively Stressed Epithelial Cells Reduces Mitochondrial Respiration and Metabolism. Frontiers in Immunology. 12: 628062. PMID 33746964 DOI: 10.3389/fimmu.2021.628062 |
0.653 |
|
| 2021 |
Schnabolk G, Obert E, Banda NK, Rohrer B. Systemic Inflammation by Collagen-Induced Arthritis Affects the Progression of Age-Related Macular Degeneration Differently in Two Mouse Models of the Disease. Investigative Ophthalmology & Visual Science. 61: 11. PMID 33289791 DOI: 10.1167/iovs.61.14.11 |
0.787 |
|
| 2020 |
Nicholson C, Ishii M, Annamalai B, Chandler K, Chwa M, Kenney MC, Shah N, Rohrer B. J or H mtDNA haplogroups in retinal pigment epithelial cells: Effects on cell physiology, cargo in extracellular vesicles, and differential uptake of such vesicles by naïve recipient cells. Biochimica Et Biophysica Acta. General Subjects. 129798. PMID 33217521 DOI: 10.1016/j.bbagen.2020.129798 |
0.795 |
|
| 2020 |
Annamalai B, Parsons N, Brandon C, Rohrer B. The use of Matrigel combined with encapsulated cell technology to deliver a complement inhibitor in a mouse model of choroidal neovascularization. Molecular Vision. 26: 370-377. PMID 32476817 |
0.637 |
|
| 2020 |
Belhaj M, Annamalai B, Parsons N, Shuler A, Potts J, Rohrer B. Encapsulated Cell Technology for the Delivery of Biologics to the Mouse Eye. Journal of Visualized Experiments : Jove. PMID 32281978 DOI: 10.3791/60162 |
0.622 |
|
| 2020 |
Annamalai B, Nicholson C, Parsons N, Stephenson S, Atkinson C, Jones B, Rohrer B. Immunization Against Oxidized Elastin Exacerbates Structural and Functional Damage in Mouse Model of Smoke-Induced Ocular Injury. Investigative Ophthalmology & Visual Science. 61: 45. PMID 32207814 DOI: 10.1167/Iovs.61.3.45 |
0.79 |
|
| 2019 |
Nicholson C, Shah N, Ishii M, Annamalai B, Brandon C, Rodgers J, Nowling T, Rohrer B. Mechanisms of extracellular vesicle uptake in stressed retinal pigment epithelial cell monolayers. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 165608. PMID 31740401 DOI: 10.1016/J.Bbadis.2019.165608 |
0.788 |
|
| 2019 |
Schnabolk G, Rohrer B, Simpson KN. Increased Nonexudative Age-Related Macular Degeneration Diagnosis Among Medicare Beneficiaries With Rheumatoid Arthritis. Investigative Ophthalmology & Visual Science. 60: 3520-3526. PMID 31412111 DOI: 10.1167/Iovs.18-26444 |
0.772 |
|
| 2019 |
Ishii M, Beeson G, Beeson C, Rohrer B. An improved method for isolation of mitochondria from cell lines that enables reconstitution of calcium-dependent processes. Analytical Biochemistry. 577: 52-58. PMID 31022379 DOI: 10.1016/J.Ab.2019.04.012 |
0.642 |
|
| 2019 |
Rohrer B, Frazer-Abel A, Leonard A, Ratnapriya R, Ward T, Pietraszkiewicz A, O'Quinn E, Adams K, Swaroop A, Wolf BJ. Association of age-related macular degeneration with complement activation products, smoking, and single nucleotide polymorphisms in South Carolinians of European and African descent. Molecular Vision. 25: 79-92. PMID 30820144 |
0.606 |
|
| 2019 |
Parsons N, Annamalai B, Obert E, Schnabolk G, Tomlinson S, Rohrer B. Inhibition of the alternative complement pathway accelerates repair processes in the murine model of choroidal neovascularization. Molecular Immunology. 108: 8-12. PMID 30763805 DOI: 10.1016/J.Molimm.2019.02.001 |
0.789 |
|
| 2018 |
Ishii M, Rohrer B. Correction: Mechanisms of bystander effects in retinal pigment epithelium cell networks. Cell Death & Disease. 9: 786. PMID 30013064 DOI: 10.1038/S41419-018-0831-3 |
0.504 |
|
| 2018 |
Rohrer B. Anaphylatoxin Signaling in Retinal Pigment and Choroidal Endothelial Cells: Characteristics and Relevance to Age-Related Macular Degeneration. Advances in Experimental Medicine and Biology. 1074: 45-51. PMID 29721926 DOI: 10.1007/978-3-319-75402-4_6 |
0.461 |
|
| 2018 |
Shah N, Ishii M, Brandon C, Ablonczy Z, Cai J, Liu Y, Chou J, Rohrer B. Extracellular vesicle-mediated long-range communication in stressed retinal pigment epithelial cell monolayers. Biochimica Et Biophysica Acta. PMID 29684588 DOI: 10.1016/J.Bbadis.2018.04.016 |
0.782 |
|
| 2018 |
Annamalai B, Parsons N, Belhaj M, Brandon C, Potts J, Rohrer B. Encapsulated Cell Technology-Based Delivery of a Complement Inhibitor Reduces Choroidal Neovascularization in a Mouse Model. Translational Vision Science & Technology. 7: 3. PMID 29576927 DOI: 10.1167/Tvst.7.2.3 |
0.691 |
|
| 2018 |
Schnabolk G, Parsons N, Obert E, Annamalai B, Nasarre C, Tomlinson S, Lewin AS, Rohrer B. Delivery of CR2-fH Using AAV Vector Therapy as Treatment Strategy in the Mouse Model of Choroidal Neovascularization. Molecular Therapy. Methods & Clinical Development. 9: 1-11. PMID 29234687 DOI: 10.1016/J.Omtm.2017.11.003 |
0.794 |
|
| 2017 |
Shi Y, Obert E, Rahman B, Rohrer B, Lobo GP. The Retinol Binding Protein Receptor 2 (Rbpr2) is required for Photoreceptor Outer Segment Morphogenesis and Visual Function in Zebrafish. Scientific Reports. 7: 16207. PMID 29176573 DOI: 10.1038/S41598-017-16498-9 |
0.784 |
|
| 2017 |
Ishii M, Rohrer B. Mechanisms of bystander effects in retinal pigment epithelium cell networks. Cell Death & Disease. 8: e3061. PMID 28981111 DOI: 10.1038/Cddis.2017.449 |
0.518 |
|
| 2017 |
Lobo GP, Fulmer D, Guo L, Zuo X, Dang Y, Kim SH, Su Y, George K, Obert E, Fogelgren B, Nihalani D, Norris RA, Rohrer B, Lipschutz JH. The exocyst is required for photoreceptor ciliogenesis and retinal development. The Journal of Biological Chemistry. PMID 28729419 DOI: 10.1074/Jbc.M117.795674 |
0.795 |
|
| 2017 |
Busch C, Annamalai B, Abdusalamova K, Reichhart N, Huber C, Lin Y, Jo EAH, Zipfel PF, Skerka C, Wildner G, Diedrichs-Möhring M, Rohrer B, Strauß O. Anaphylatoxins Activate Ca(2+), Akt/PI3-Kinase, and FOXO1/FoxP3 in the Retinal Pigment Epithelium. Frontiers in Immunology. 8: 703. PMID 28663750 DOI: 10.3389/Fimmu.2017.00703 |
0.411 |
|
| 2017 |
Schnabolk G, Beon MK, Tomlinson S, Rohrer B. New Insights on Complement Inhibitor CD59 in Mouse Laser-Induced Choroidal Neovascularization: Mislocalization After Injury and Targeted Delivery for Protein Replacement. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. PMID 28333572 DOI: 10.1089/jop.2016.0101 |
0.792 |
|
| 2017 |
Ishii M, Rohrer B. Bystander effects elicited by single-cell photo-oxidative blue-light stimulation in retinal pigment epithelium cell networks. Cell Death Discovery. 3: 16071. PMID 28179989 DOI: 10.1038/Cddiscovery.2016.71 |
0.526 |
|
| 2017 |
Obert E, Strauss R, Brandon C, Grek C, Ghatnekar G, Gourdie R, Rohrer B. Targeting the tight junction protein, zonula occludens-1, with the connexin43 mimetic peptide, αCT1, reduces VEGF-dependent RPE pathophysiology. Journal of Molecular Medicine (Berlin, Germany). PMID 28132078 DOI: 10.1007/S00109-017-1506-8 |
0.81 |
|
| 2017 |
Rohrer B, Schnabolk G, Annamalei B, Parsons N, Potts J, Lewin A, Tomlinson SM. Delivery of CR2-fH using AAV vector therapy and encapsulated cell technology as treatment strategies in mouse model of neovascularization Molecular Immunology. 89: 202. DOI: 10.1016/J.Molimm.2017.06.230 |
0.772 |
|
| 2016 |
Song D, Wilson B, Zhao L, Bhuyan R, Bandyopadhyay M, Lyubarsky A, Yu C, Li Y, Kanu L, Miwa T, Song WC, Finnemann SC, Rohrer B, Dunaief JL. Retinal Pre-Conditioning by CD59a Knockout Protects against Light-Induced Photoreceptor Degeneration. Plos One. 11: e0166348. PMID 27893831 DOI: 10.1371/Journal.Pone.0166348 |
0.424 |
|
| 2016 |
Holers VM, Tomlinson S, Kulik L, Atkinson C, Rohrer B, Banda N, Thurman JM. New therapeutic and diagnostic opportunities for injured tissue-specific targeting of complement inhibitors and imaging modalities. Seminars in Immunology. PMID 27282113 DOI: 10.1016/J.Smim.2016.05.007 |
0.732 |
|
| 2016 |
Woodell A, Jones BW, Williamson T, Schnabolk G, Tomlinson S, Atkinson C, Rohrer B. A Targeted Inhibitor of the Alternative Complement Pathway Accelerates Recovery From Smoke-Induced Ocular Injury. Investigative Ophthalmology & Visual Science. 57: 1728-37. PMID 27064393 DOI: 10.1167/Iovs.15-18471 |
0.787 |
|
| 2016 |
Coughlin B, Schnabolk G, Joseph K, Raikwar H, Kunchithapautham K, Johnson K, Moore K, Wang Y, Rohrer B. Connecting the innate and adaptive immune responses in mouse choroidal neovascularization via the anaphylatoxin C5a and γδT-cells. Scientific Reports. 6: 23794. PMID 27029558 DOI: 10.1038/Srep23794 |
0.775 |
|
| 2016 |
Rohrer B, Bandyopadhyay M, Beeson C. Reduced Metabolic Capacity in Aged Primary Retinal Pigment Epithelium (RPE) is Correlated with Increased Susceptibility to Oxidative Stress. Advances in Experimental Medicine and Biology. 854: 793-8. PMID 26427491 DOI: 10.1007/978-3-319-17121-0_106 |
0.636 |
|
| 2016 |
Beeson C, Lindsey C, Nasarre C, Bandyopadhyay M, Perron N, Rohrer B. Small Molecules that Protect Mitochondrial Function from Metabolic Stress Decelerate Loss of Photoreceptor Cells in Murine Retinal Degeneration Models. Advances in Experimental Medicine and Biology. 854: 449-54. PMID 26427445 DOI: 10.1007/978-3-319-17121-0_60 |
0.64 |
|
| 2016 |
Pujol-Lereis LM, Schäfer N, Kuhn LB, Rohrer B, Pauly D. Interrelation Between Oxidative Stress and Complement Activation in Models of Age-Related Macular Degeneration. Advances in Experimental Medicine and Biology. 854: 87-93. PMID 26427398 DOI: 10.1007/978-3-319-17121-0_13 |
0.405 |
|
| 2015 |
Schnabolk G, Coughlin B, Joseph K, Kunchithapautham K, Bandyopadhyay M, O'Quinn EC, Nowling T, Rohrer B. Local production of the alternative pathway component factor B is sufficient to promote laser-induced choroidal neovascularization. Investigative Ophthalmology & Visual Science. 56: 1850-63. PMID 25593023 DOI: 10.1167/Iovs.14-15910 |
0.793 |
|
| 2015 |
Leonard AP, Cameron RB, Speiser JL, Wolf BJ, Peterson YK, Schnellmann RG, Beeson CC, Rohrer B. Quantitative analysis of mitochondrial morphology and membrane potential in living cells using high-content imaging, machine learning, and morphological binning. Biochimica Et Biophysica Acta. 1853: 348-60. PMID 25447550 DOI: 10.1016/J.Bbamcr.2014.11.002 |
0.676 |
|
| 2015 |
Genewsky A, Jost I, Busch C, Huber C, Stindl J, Skerka C, Zipfel PF, Rohrer B, Strauß O. Activation of endogenously expressed ion channels by active complement in the retinal pigment epithelium. PflüGers Archiv : European Journal of Physiology. 467: 2179-91. PMID 25427445 DOI: 10.1007/S00424-014-1656-2 |
0.318 |
|
| 2014 |
Schnabolk G, Stauffer K, O'Quinn E, Coughlin B, Kunchithapautham K, Rohrer B. A comparative analysis of C57BL/6J and 6N substrains; chemokine/cytokine expression and susceptibility to laser-induced choroidal neovascularization. Experimental Eye Research. 129: 18-23. PMID 25305577 DOI: 10.1016/J.Exer.2014.10.005 |
0.783 |
|
| 2014 |
Kunchithapautham K, Atkinson C, Rohrer B. Smoke exposure causes endoplasmic reticulum stress and lipid accumulation in retinal pigment epithelium through oxidative stress and complement activation. The Journal of Biological Chemistry. 289: 14534-46. PMID 24711457 DOI: 10.1074/Jbc.M114.564674 |
0.8 |
|
| 2014 |
Schnabolk G, Tomlinson S, Rohrer B. The complement regulatory protein CD59: insights into attenuation of choroidal neovascularization. Advances in Experimental Medicine and Biology. 801: 435-40. PMID 24664728 DOI: 10.1007/978-1-4614-3209-8_55 |
0.795 |
|
| 2014 |
Woodell A, Rohrer B. A mechanistic review of cigarette smoke and age-related macular degeneration. Advances in Experimental Medicine and Biology. 801: 301-7. PMID 24664711 DOI: 10.1007/978-1-4614-3209-8_38 |
0.798 |
|
| 2014 |
Rohrer B, Kunchithapautham K, Genewsky A, Strauß O. Prolonged SRC kinase activation, a mechanism to turn transient, sublytic complement activation into a sustained pathological condition in retinal pigment epithelium cells. Advances in Experimental Medicine and Biology. 801: 221-7. PMID 24664702 DOI: 10.1007/978-1-4614-3209-8_29 |
0.762 |
|
| 2013 |
Woodell A, Coughlin B, Kunchithapautham K, Casey S, Williamson T, Ferrell WD, Atkinson C, Jones BW, Rohrer B. Alternative complement pathway deficiency ameliorates chronic smoke-induced functional and morphological ocular injury. Plos One. 8: e67894. PMID 23825688 DOI: 10.1371/Journal.Pone.0067894 |
0.806 |
|
| 2013 |
Whitcup SM, Sodhi A, Atkinson JP, Holers VM, Sinha D, Rohrer B, Dick AD. The role of the immune response in age-related macular degeneration. International Journal of Inflammation. 2013: 348092. PMID 23762772 DOI: 10.1155/2013/348092 |
0.525 |
|
| 2013 |
Thurman JM, Kulik L, Orth H, Wong M, Renner B, Sargsyan SA, Mitchell LM, Hourcade DE, Hannan JP, Kovacs JM, Coughlin B, Woodell AS, Pickering MC, Rohrer B, Holers VM. Detection of complement activation using monoclonal antibodies against C3d. The Journal of Clinical Investigation. 123: 2218-30. PMID 23619360 DOI: 10.1172/Jci65861 |
0.784 |
|
| 2013 |
Joseph K, Kulik L, Coughlin B, Kunchithapautham K, Bandyopadhyay M, Thiel S, Thielens NM, Holers VM, Rohrer B. Oxidative stress sensitizes retinal pigmented epithelial (RPE) cells to complement-mediated injury in a natural antibody-, lectin pathway-, and phospholipid epitope-dependent manner. The Journal of Biological Chemistry. 288: 12753-65. PMID 23493397 DOI: 10.1074/Jbc.M112.421891 |
0.816 |
|
| 2013 |
Thurman JM, Rohrer B. Noninvasive detection of complement activation through radiologic imaging. Advances in Experimental Medicine and Biology. 735: 271-82. PMID 23402034 DOI: 10.1007/978-1-4614-4118-2_19 |
0.338 |
|
| 2013 |
Holers VM, Rohrer B, Tomlinson S. CR2-mediated targeting of complement inhibitors: bench-to-bedside using a novel strategy for site-specific complement modulation. Advances in Experimental Medicine and Biology. 735: 137-54. PMID 23402024 DOI: 10.1007/978-1-4614-4118-2_9 |
0.666 |
|
| 2013 |
Jarrett SG, Rohrer B, Perron NR, Beeson C, Boulton ME. Assessment of mitochondrial damage in retinal cells and tissues using quantitative polymerase chain reaction for mitochondrial DNA damage and extracellular flux assay for mitochondrial respiration activity. Methods in Molecular Biology (Clifton, N.J.). 935: 227-43. PMID 23150372 DOI: 10.1007/978-1-62703-080-9_16 |
0.599 |
|
| 2013 |
Perron NR, Beeson C, Rohrer B. Early alterations in mitochondrial reserve capacity; a means to predict subsequent photoreceptor cell death. Journal of Bioenergetics and Biomembranes. 45: 101-9. PMID 23090843 DOI: 10.1007/S10863-012-9477-5 |
0.607 |
|
| 2013 |
Rohrer B, Kulik L, Mitchell L, Hourcade D, Hannan J, Coughlin B, Woodell A, Pickering M, Holers V, Thurman J. Novel monoclonal antibodies to C3d for non-invasively monitoring the activity of complement in glomerular and retinal disease Molecular Immunology. 56: 264. DOI: 10.1016/J.Molimm.2013.05.073 |
0.785 |
|
| 2012 |
Bandyopadhyay M, Rohrer B. Matrix metalloproteinase activity creates pro-angiogenic environment in primary human retinal pigment epithelial cells exposed to complement. Investigative Ophthalmology & Visual Science. 53: 1953-61. PMID 22408008 DOI: 10.1167/Iovs.11-8638 |
0.35 |
|
| 2012 |
Rohrer B, Coughlin B, Bandyopadhyay M, Holers VM. Systemic human CR2-targeted complement alternative pathway inhibitor ameliorates mouse laser-induced choroidal neovascularization. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 28: 402-9. PMID 22309197 DOI: 10.1089/Jop.2011.0212 |
0.582 |
|
| 2012 |
Kunchithapautham K, Bandyopadhyay M, Dahrouj M, Thurman JM, Rohrer B. Sublytic membrane-attack-complex activation and VEGF secretion in retinal pigment epithelial cells. Advances in Experimental Medicine and Biology. 723: 23-30. PMID 22183311 DOI: 10.1007/978-1-4614-0631-0_4 |
0.762 |
|
| 2012 |
Rohrer B, Kunchithapautham K, Genewski A, Strauss O. Prolonged voltage-gated calcium channel activation by sublytic complement activation in retinal pigment epithelium, a mechanism for controlling VEGF secretion Immunobiology. 217: 1194-1195. DOI: 10.1016/J.Imbio.2012.08.188 |
0.729 |
|
| 2012 |
Thurman JM, Kulik L, Mitchell LM, Hourcade DE, Hannan JP, Coughlin B, Woodell AS, Pickering MC, Rohrer B, Holers M. Novel monoclonal antibodies to C3d that target and identify in living animals sites of complement activation Immunobiology. 217: 1191. DOI: 10.1016/J.Imbio.2012.08.179 |
0.768 |
|
| 2011 |
Kunchithapautham K, Rohrer B. Sublytic membrane-attack-complex (MAC) activation alters regulated rather than constitutive vascular endothelial growth factor (VEGF) secretion in retinal pigment epithelium monolayers. The Journal of Biological Chemistry. 286: 23717-24. PMID 21566137 DOI: 10.1074/Jbc.M110.214593 |
0.746 |
|
| 2011 |
Kunchithapautham K, Coughlin B, Lemasters JJ, Rohrer B. Differential effects of rapamycin on rods and cones during light-induced stress in albino mice. Investigative Ophthalmology & Visual Science. 52: 2967-75. PMID 21273550 DOI: 10.1167/Iovs.10-6278 |
0.747 |
|
| 2011 |
Rohrer B, Coughlin B, Kunchithapautham K, Long Q, Tomlinson S, Takahashi K, Holers VM. The alternative pathway is required, but not alone sufficient, for retinal pathology in mouse laser-induced choroidal neovascularization. Molecular Immunology. 48: e1-8. PMID 21257205 DOI: 10.1016/J.Molimm.2010.12.016 |
0.807 |
|
| 2011 |
Li X, Li W, Dai X, Kong F, Zheng Q, Zhou X, Lü F, Chang B, Rohrer B, Hauswirth WW, Qu J, Pang JJ. Gene therapy rescues cone structure and function in the 3-month-old rd12 mouse: a model for midcourse RPE65 leber congenital amaurosis. Investigative Ophthalmology & Visual Science. 52: 7-15. PMID 21169527 DOI: 10.1167/Iovs.10-6138 |
0.374 |
|
| 2010 |
Rohrer B, Long Q, Coughlin B, Renner B, Huang Y, Kunchithapautham K, Ferreira VP, Pangburn MK, Gilkeson GS, Thurman JM, Tomlinson S, Holers VM. A targeted inhibitor of the complement alternative pathway reduces RPE injury and angiogenesis in models of age-related macular degeneration. Advances in Experimental Medicine and Biology. 703: 137-49. PMID 20711712 DOI: 10.1007/978-1-4419-5635-4_10 |
0.825 |
|
| 2010 |
Ogando DG, Dahlquist KD, Alizadeh M, Kunchithapautham K, Li J, Yu N, LaVail MM, Rohrer B, Vollrath D, Danciger M. Candidate genes for chromosomes 6 and 10 quantitative trait loci for age-related retinal degeneration in mice. Molecular Vision. 16: 1004-18. PMID 20577653 |
0.767 |
|
| 2010 |
Thurman JM, Renner B, Kunchithapautham K, Holers VM, Rohrer B. Aseptic injury to epithelial cells alters cell surface complement regulation in a tissue specific fashion. Advances in Experimental Medicine and Biology. 664: 151-8. PMID 20238013 DOI: 10.1007/978-1-4419-1399-9_18 |
0.773 |
|
| 2010 |
Pang J, Boye SE, Lei B, Boye SL, Everhart D, Ryals R, Umino Y, Rohrer B, Alexander J, Li J, Dai X, Li Q, Chang B, Barlow R, Hauswirth WW. Self-complementary AAV-mediated gene therapy restores cone function and prevents cone degeneration in two models of Rpe65 deficiency. Gene Therapy. 17: 815-26. PMID 20237510 DOI: 10.1038/Gt.2010.29 |
0.373 |
|
| 2009 |
Kunchithapautham K, Coughlin B, Crouch RK, Rohrer B. Cone outer segment morphology and cone function in the Rpe65-/- Nrl-/- mouse retina are amenable to retinoid replacement. Investigative Ophthalmology & Visual Science. 50: 4858-64. PMID 19407011 DOI: 10.1167/Iovs.08-3008 |
0.768 |
|
| 2009 |
Thurman JM, Renner B, Kunchithapautham K, Ferreira VP, Pangburn MK, Ablonczy Z, Tomlinson S, Holers VM, Rohrer B. Oxidative stress renders retinal pigment epithelial cells susceptible to complement-mediated injury. The Journal of Biological Chemistry. 284: 16939-47. PMID 19386604 DOI: 10.1074/Jbc.M808166200 |
0.814 |
|
| 2009 |
Rohrer B, Long Q, Coughlin B, Wilson RB, Huang Y, Qiao F, Tang PH, Kunchithapautham K, Gilkeson GS, Tomlinson S. A targeted inhibitor of the alternative complement pathway reduces angiogenesis in a mouse model of age-related macular degeneration. Investigative Ophthalmology & Visual Science. 50: 3056-64. PMID 19264882 DOI: 10.1167/Iovs.08-2222 |
0.797 |
|
| 2008 |
Rohrer B, Long Q, Wilson B, Coughlin B, Huang Y, Qiao F, Tang P, Kunchithapautham K, Gilkeson G, Tomlinson S. Alternative complement pathway signalling in a mouse model of choroidal neovascularisation Molecular Immunology. 45: 4162. DOI: 10.1016/J.Molimm.2008.08.201 |
0.77 |
|
| 2008 |
Rohrer B, Renner B, Kunchithapautham K, Ablonczy Z, Tomlinson S, Thurman J. Oxidative stress renders retinal epithelial cells susceptible to complement mediated injury Molecular Immunology. 45: 4162. DOI: 10.1016/J.Molimm.2008.08.200 |
0.79 |
|
| 2007 |
Rohrer B, Guo Y, Kunchithapautham K, Gilkeson GS. Eliminating complement factor D reduces photoreceptor susceptibility to light-induced damage. Investigative Ophthalmology & Visual Science. 48: 5282-9. PMID 17962484 DOI: 10.1167/Iovs.07-0282 |
0.75 |
|
| 2007 |
Wilson RB, Kunchithapautham K, Rohrer B. Paradoxical role of BDNF: BDNF+/- retinas are protected against light damage-mediated stress. Investigative Ophthalmology & Visual Science. 48: 2877-86. PMID 17525224 DOI: 10.1167/Iovs.06-1079 |
0.718 |
|
| 2007 |
Kunchithapautham K, Rohrer B. Apoptosis and autophagy in photoreceptors exposed to oxidative stress. Autophagy. 3: 433-41. PMID 17471016 DOI: 10.4161/Auto.4294 |
0.754 |
|
| 2007 |
Sharma AK, Rohrer B. Sustained elevation of intracellular cGMP causes oxidative stress triggering calpain-mediated apoptosis in photoreceptor degeneration. Current Eye Research. 32: 259-69. PMID 17453946 DOI: 10.1080/02713680601161238 |
0.509 |
|
| 2007 |
Kunchithapautham K, Rohrer B. Autophagy is one of the multiple mechanisms active in photoreceptor degeneration. Autophagy. 3: 65-6. PMID 17102584 DOI: 10.4161/Auto.3431 |
0.763 |
|
| 2007 |
Rohrer B, Demos C, Frigg R, Grimm C. Classical complement activation and acquired immune response pathways are not essential for retinal degeneration in the rd1 mouse. Experimental Eye Research. 84: 82-91. PMID 17069800 DOI: 10.1016/J.Exer.2006.08.017 |
0.399 |
|
| 2006 |
Lohr HR, Kuntchithapautham K, Sharma AK, Rohrer B. Multiple, parallel cellular suicide mechanisms participate in photoreceptor cell death. Experimental Eye Research. 83: 380-9. PMID 16626700 DOI: 10.1016/J.Exer.2006.01.014 |
0.537 |
|
| 2006 |
Lohr HR, Kuntchithapautham K, Sharma AK, Rohrer B. Erratum to “Multiple, parallel cellular suicide mechanisms participate in photoreceptor cell death” [Exp. Eye Res. 83 (2006) 380–389] Experimental Eye Research. 83: 1522. DOI: 10.1016/J.Exer.2006.09.001 |
0.425 |
|
| 2003 |
Rohrer B, Matthes MT, LaVail MM, Reichardt LF. Lack of p75 receptor does not protect photoreceptors from light-induced cell death. Experimental Eye Research. 76: 125-9. PMID 12589782 DOI: 10.1016/S0014-4835(02)00258-0 |
0.676 |
|
| 2002 |
Ablonczy Z, Crouch RK, Goletz PW, Redmond TM, Knapp DR, Ma JX, Rohrer B. 11-cis-retinal reduces constitutive opsin phosphorylation and improves quantum catch in retinoid-deficient mouse rod photoreceptors. The Journal of Biological Chemistry. 277: 40491-8. PMID 12176991 DOI: 10.1074/Jbc.M205507200 |
0.5 |
|
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