| Year |
Citation |
Score |
| 2022 |
Mayor F, Murga C. G Protein-Coupled Receptor Kinases Take Central Stage. Cells. 12. PMID 36611817 DOI: 10.3390/cells12010023 |
0.391 |
|
| 2022 |
Neves M, Marolda V, Mayor F, Penela P. Crosstalk between CXCR4/ACKR3 and EGFR Signaling in Breast Cancer Cells. International Journal of Molecular Sciences. 23. PMID 36233192 DOI: 10.3390/ijms231911887 |
0.333 |
|
| 2021 |
Reglero C, Ortiz Del Castillo B, Rivas V, Mayor F, Penela P. Mdm2-Mediated Downmodulation of GRK2 Restricts Centrosome Separation for Proper Chromosome Congression. Cells. 10. PMID 33806062 DOI: 10.3390/cells10040729 |
0.367 |
|
| 2020 |
Neves M, Perpiñá-Viciano C, Penela P, Hoffmann C, Mayor F. Modulation of CXCR4-Mediated Gi1 Activation by EGF Receptor and GRK2. Acs Pharmacology & Translational Science. 3: 627-634. PMID 33073183 DOI: 10.1021/acsptsci.0c00021 |
0.39 |
|
| 2020 |
Smit MJ, Schlecht-Louf G, Neves M, den Bor JV, Penela P, Siderius M, Bachelerie F, Mayor F. The CXCL12/CXCR4/ACKR3 Axis in the Tumor Microenvironment: Signaling, Crosstalk, and Therapeutic Targeting. Annual Review of Pharmacology and Toxicology. PMID 32956018 DOI: 10.1146/Annurev-Pharmtox-010919-023340 |
0.336 |
|
| 2020 |
Vila-Bedmar R, Cruces-Sande M, Arcones AC, Willemen HLDM, Prieto P, Moreno-Indias I, Díaz-Rodríguez D, Francisco S, Jaén RI, Gutiérrez-Repiso C, Heijnen CJ, Boscá L, Fresno M, Kavelaars A, Mayor F, et al. GRK2 levels in myeloid cells modulate adipose-liver crosstalk in high fat diet-induced obesity. Cellular and Molecular Life Sciences : Cmls. PMID 31927610 DOI: 10.1007/S00018-019-03442-5 |
0.328 |
|
| 2020 |
Cruces-Sande M, Arcones AC, Vila-Bedmar R, Val-Blasco A, Sharabi K, Díaz-Rodríguez D, Puigserver P, Mayor F, Murga C. Autophagy mediates hepatic GRK2 degradation to facilitate glucagon-induced metabolic adaptation to fasting. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 34: 399-409. PMID 31914606 DOI: 10.1096/Fj.201901444R |
0.411 |
|
| 2019 |
Palacios-García J, Sanz-Flores M, Asensio A, Alvarado R, Rojo-Berciano S, Stamatakis K, Paramio JM, Cano A, Nieto MA, García-Escudero R, Mayor F, Ribas C. G-protein coupled receptor kinase 2 safeguards epithelial phenotype in Head and Neck Squamous Cell Carcinomas. International Journal of Cancer. PMID 31850518 DOI: 10.1002/Ijc.32838 |
0.386 |
|
| 2019 |
Arcones AC, Cruces-Sande M, Ramos P, Mayor F, Murga C. Sex Differences in High Fat Diet-Induced Metabolic Alterations Correlate with Changes in the Modulation of GRK2 Levels. Cells. 8. PMID 31752326 DOI: 10.3390/Cells8111464 |
0.341 |
|
| 2019 |
Ruso-Julve F, Pombero A, Pilar-Cuéllar F, García-Díaz N, Garcia-Lopez R, Juncal-Ruiz M, Castro E, Díaz Á, Vazquez-Bourgón J, García-Blanco A, Garro-Martinez E, Pisonero H, Estirado A, Ayesa-Arriola R, López-Giménez J, ... Mayor F, et al. Dopaminergic control of ADAMTS2 expression through cAMP/CREB and ERK: molecular effects of antipsychotics. Translational Psychiatry. 9: 306. PMID 31740729 DOI: 10.1038/S41398-019-0647-7 |
0.331 |
|
| 2019 |
Penela P, Inserte J, Ramos P, Rodriguez-Sinovas A, Garcia-Dorado D, Mayor F. Degradation of GRK2 and AKT is an early and detrimental event in myocardial ischemia/reperfusion. Ebiomedicine. PMID 31594751 DOI: 10.1016/J.Ebiom.2019.09.019 |
0.349 |
|
| 2019 |
Penela P, Ribas C, Sánchez-Madrid F, Mayor F. G protein-coupled receptor kinase 2 (GRK2) as a multifunctional signaling hub. Cellular and Molecular Life Sciences : Cmls. PMID 31432234 DOI: 10.1007/S00018-019-03274-3 |
0.526 |
|
| 2019 |
Aluja D, Inserte J, Penela P, Ramos P, Ribas C, Iñiguez MÁ, Mayor F, Garcia-Dorado D. Calpains mediate isoproterenol-induced hypertrophy through modulation of GRK2. Basic Research in Cardiology. 114: 21. PMID 30915659 DOI: 10.1007/S00395-019-0730-5 |
0.391 |
|
| 2019 |
Murga C, Arcones AC, Cruces-Sande M, Briones AM, Salaices M, Mayor F. G Protein-Coupled Receptor Kinase 2 (GRK2) as a Potential Therapeutic Target in Cardiovascular and Metabolic Diseases. Frontiers in Pharmacology. 10: 112. PMID 30837878 DOI: 10.3389/Fphar.2019.00112 |
0.452 |
|
| 2019 |
Fumagalli A, Zarca A, Neves M, Caspar B, Hill SJ, Mayor F, Smit MJ, Marin P. CXCR4/ACKR3 phosphorylation and recruitment of interacting proteins: key mechanisms regulating their functional status. Molecular Pharmacology. PMID 30837297 DOI: 10.1124/Mol.118.115360 |
0.48 |
|
| 2018 |
Cruces-Sande M, Vila-Bedmar R, Arcones AC, González-Rodríguez Á, Rada P, Gutiérrez-de-Juan V, Vargas-Castrillón J, Iruzubieta P, Sánchez-González C, Formentini L, Crespo J, García-Monzón C, Martínez-Chantar ML, Valverde ÁM, Mayor F, et al. Involvement of G protein-coupled receptor kinase 2 (GRK2) in the development of non-alcoholic steatosis and steatohepatitis in mice and humans. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 1864: 3655-3667. PMID 30261289 DOI: 10.1016/J.Bbadis.2018.09.027 |
0.346 |
|
| 2018 |
Mayor F, Cruces-Sande M, Arcones AC, Vila-Bedmar R, Briones AM, Salaices M, Murga C. G protein-coupled receptor kinase 2 (GRK2) as an integrative signalling node in the regulation of cardiovascular function and metabolic homeostasis. Cellular Signalling. 41: 25-32. PMID 28389415 DOI: 10.1016/J.Cellsig.2017.04.002 |
0.411 |
|
| 2017 |
Nogués L, Palacios-García J, Reglero C, Rivas V, Neves M, Ribas C, Penela P, Mayor F. G protein-coupled receptor kinases (GRKs) in tumorigenesis and cancer progression: GPCR regulators and signaling hubs. Seminars in Cancer Biology. PMID 28473253 DOI: 10.1016/J.Semcancer.2017.04.013 |
0.454 |
|
| 2017 |
Nogués L, Reglero C, Rivas V, Neves M, Penela P, Mayor F. G-Protein-Coupled Receptor Kinase 2 as a Potential Modulator of the Hallmarks of Cancer. Molecular Pharmacology. 91: 220-228. PMID 27895163 DOI: 10.1124/Mol.116.107185 |
0.421 |
|
| 2016 |
Lucas E, Vila-Bedmar R, Arcones AC, Cruces-Sande M, Cachofeiro V, Mayor F, Murga C. Obesity-induced cardiac lipid accumulation in adult mice is modulated by G protein-coupled receptor kinase 2 levels. Cardiovascular Diabetology. 15: 155. PMID 27832814 DOI: 10.1186/S12933-016-0474-6 |
0.45 |
|
| 2016 |
Nogués L, Reglero C, Rivas V, Salcedo A, Lafarga V, Neves M, Ramos P, Mendiola M, Berjón A, Stamatakis K, Zhou XZ, Lu KP, Hardisson D, Mayor F, Penela P. G Protein-coupled Receptor Kinase 2 (GRK2) Promotes Breast Tumorigenesis Through a HDAC6-Pin1 Axis. Ebiomedicine. PMID 27720394 DOI: 10.1016/J.Ebiom.2016.09.030 |
0.364 |
|
| 2016 |
Singhmar P, Huo X, Eijkelkamp N, Berciano SR, Baameur F, Mei FC, Zhu Y, Cheng X, Hawke D, Mayor F, Murga C, Heijnen CJ, Kavelaars A. Critical role for Epac1 in inflammatory pain controlled by GRK2-mediated phosphorylation of Epac1. Proceedings of the National Academy of Sciences of the United States of America. PMID 26929333 DOI: 10.1073/Pnas.1516036113 |
0.386 |
|
| 2016 |
Sánchez-Fernández G, Cabezudo S, Caballero Á, García-Hoz C, Tall GG, Klett J, Michnick SW, Mayor F, Ribas C. Protein kinase C ζ interacts with a novel binding region of Gαq to act as functional effector protein. The Journal of Biological Chemistry. PMID 26887939 DOI: 10.1074/Jbc.M115.684308 |
0.489 |
|
| 2015 |
Lucas E, Cruces-Sande M, Briones AM, Salaices M, Mayor F, Murga C, Vila-Bedmar R. Molecular physiopathology of obesity-related diseases: multi-organ integration by GRK2. Archives of Physiology and Biochemistry. 1-15. PMID 26643283 DOI: 10.3109/13813455.2015.1107589 |
0.338 |
|
| 2015 |
Vila-Bedmar R, Cruces-Sande M, Lucas E, Willemen HL, Heijnen CJ, Kavelaars A, Mayor F, Murga C. Reversal of diet-induced obesity and insulin resistance by inducible genetic ablation of GRK2. Science Signaling. 8: ra73. PMID 26198359 DOI: 10.1126/Scisignal.Aaa4374 |
0.304 |
|
| 2014 |
Rivas V, Nogués L, Reglero C, Mayor F, Penela P. Role of G protein-coupled receptor kinase 2 in tumoral angiogenesis. Molecular & Cellular Oncology. 1: e969166. PMID 27308373 DOI: 10.4161/23723548.2014.969166 |
0.431 |
|
| 2014 |
Lucas E, Jurado-Pueyo M, Fortuño MA, Fernández-Veledo S, Vila-Bedmar R, Jiménez-Borreguero LJ, Lazcano JJ, Gao E, Gómez-Ambrosi J, Frühbeck G, Koch WJ, Díez J, Mayor F, Murga C. Downregulation of G protein-coupled receptor kinase 2 levels enhances cardiac insulin sensitivity and switches on cardioprotective gene expression patterns. Biochimica Et Biophysica Acta. 1842: 2448-56. PMID 25239306 DOI: 10.1016/J.Bbadis.2014.09.004 |
0.504 |
|
| 2014 |
Garcia-Guerra L, Vila-Bedmar R, Carrasco-Rando M, Cruces-Sande M, Martín M, Ruiz-Gómez A, Ruiz-Gómez M, Lorenzo M, Fernández-Veledo S, Mayor F, Murga C, Nieto-Vázquez I. Skeletal muscle myogenesis is regulated by G protein-coupled receptor kinase 2. Journal of Molecular Cell Biology. 6: 299-311. PMID 24927997 DOI: 10.1093/Jmcb/Mju025 |
0.39 |
|
| 2014 |
Penela P, Nogués L, Mayor F. Role of G protein-coupled receptor kinases in cell migration. Current Opinion in Cell Biology. 27: 10-7. PMID 24680425 DOI: 10.1016/J.Ceb.2013.10.005 |
0.489 |
|
| 2014 |
Willemen HL, Campos PM, Lucas E, Morreale A, Gil-Redondo R, Agut J, González FV, Ramos P, Heijnen C, Mayor F, Kavelaars A, Murga C. A novel p38 MAPK docking-groove-targeted compound is a potent inhibitor of inflammatory hyperalgesia. The Biochemical Journal. 459: 427-39. PMID 24517375 DOI: 10.1042/Bj20130172 |
0.378 |
|
| 2014 |
Fernández-Arenas E, Calleja E, Martínez-Martín N, Gharbi SI, Navajas R, García-Medel N, Penela P, Alcamí A, Mayor F, Albar JP, Alarcón B. β-Arrestin-1 mediates the TCR-triggered re-routing of distal receptors to the immunological synapse by a PKC-mediated mechanism. The Embo Journal. 33: 559-77. PMID 24502978 DOI: 10.1002/Embj.201386022 |
0.428 |
|
| 2014 |
Sánchez-Fernández G, Cabezudo S, García-Hoz C, Benincá C, Aragay AM, Mayor F, Ribas C. Gαq signalling: the new and the old. Cellular Signalling. 26: 833-48. PMID 24440667 DOI: 10.1016/J.Cellsig.2014.01.010 |
0.471 |
|
| 2014 |
Avendaño MS, Lucas E, Jurado-Pueyo M, Martínez-Revelles S, Vila-Bedmar R, Mayor F, Salaices M, Briones AM, Murga C. Increased nitric oxide bioavailability in adult GRK2 hemizygous mice protects against angiotensin II-induced hypertension. Hypertension. 63: 369-75. PMID 24191280 DOI: 10.1161/Hypertensionaha.113.01991 |
0.335 |
|
| 2013 |
Sánchez-Fernández G, Cabezudo S, García-Hoz C, Tobin AB, Mayor F, Ribas C. ERK5 activation by Gq-coupled muscarinic receptors is independent of receptor internalization and β-arrestin recruitment Plos One. 8. PMID 24358341 DOI: 10.1371/Journal.Pone.0084174 |
0.471 |
|
| 2012 |
Lafarga V, Mayor F, Penela P. The interplay between G protein-coupled receptor kinase 2 (GRK2) and histone deacetylase 6 (HDAC6) at the crossroads of epithelial cell motility. Cell Adhesion & Migration. 6: 495-501. PMID 23076141 DOI: 10.4161/Cam.21585 |
0.476 |
|
| 2012 |
Penela P, Lafarga V, Tapia O, Rivas V, Nogués L, Lucas E, Vila-Bedmar R, Murga C, Mayor F. Roles of GRK2 in cell signaling beyond GPCR desensitization: GRK2-HDAC6 interaction modulates cell spreading and motility. Science Signaling. 5: pt3. PMID 22589388 DOI: 10.1126/Scisignal.2003098 |
0.467 |
|
| 2012 |
García-Hoz C, Sánchez-Fernández G, García-Escudero R, Fernández-Velasco M, Palacios-García J, Ruiz-Meana M, Díaz-Meco MT, Leitges M, Moscat J, García-Dorado D, Boscá L, Mayor F, Ribas C. Protein kinase C (PKC)ζ-mediated Gαq stimulation of ERK5 protein pathway in cardiomyocytes and cardiac fibroblasts. The Journal of Biological Chemistry. 287: 7792-802. PMID 22232556 DOI: 10.1074/Jbc.M111.282210 |
0.399 |
|
| 2012 |
Lafarga V, Aymerich I, Tapia O, Mayor F, Penela P. A novel GRK2/HDAC6 interaction modulates cell spreading and motility. The Embo Journal. 31: 856-69. PMID 22193721 DOI: 10.1038/Emboj.2011.466 |
0.418 |
|
| 2011 |
Aymerich MS, López-Azcárate J, Bonaventura J, Navarro G, Fernández-Suárez D, Casadó V, Mayor F, Lluís C, Valencia M, Artieda J, Franco R. Real-Time G-Protein-Coupled Receptor Imaging to Understand and Quantify Receptor Dynamics The Scientific World Journal. 11: 1995-2010. PMID 22125451 DOI: 10.1100/2011/690858 |
0.423 |
|
| 2011 |
Mayor F, Lucas E, Jurado-Pueyo M, Garcia-Guerra L, Nieto-Vazquez I, Vila-Bedmar R, Fernández-Veledo S, Murga C. G Protein-coupled receptor kinase 2 (GRK2): A novel modulator of insulin resistance. Archives of Physiology and Biochemistry. 117: 125-30. PMID 21615207 DOI: 10.3109/13813455.2011.584693 |
0.481 |
|
| 2011 |
Molnar C, Ruiz-Gómez A, Martín M, Rojo-Berciano S, Mayor F, de Celis JF. Role of the drosophila non-visual ß-arrestin kurtz in hedgehog signalling Plos Genetics. 7. PMID 21437272 DOI: 10.1371/Journal.Pgen.1001335 |
0.399 |
|
| 2011 |
Nogués L, Salcedo A, Mayor F, Penela P. Multiple scaffolding functions of {beta}-arrestins in the degradation of G protein-coupled receptor kinase 2. The Journal of Biological Chemistry. 286: 1165-73. PMID 21081496 DOI: 10.1074/Jbc.M110.203406 |
0.514 |
|
| 2010 |
Murga C, Penela P, Ribas C, Mayor F. G protein-coupled receptor kinases: Specific phosphorylation of 7TM receptors and beyond Drug Discovery Today: Technologies. 7. PMID 24103684 DOI: 10.1016/J.Ddtec.2010.05.002 |
0.524 |
|
| 2010 |
Garcia-Guerra L, Nieto-Vazquez I, Vila-Bedmar R, Jurado-Pueyo M, Zalba G, Díez J, Murga C, Fernández-Veledo S, Mayor F, Lorenzo M. G protein-coupled receptor kinase 2 plays a relevant role in insulin resistance and obesity. Diabetes. 59: 2407-17. PMID 20627936 DOI: 10.2337/Db10-0771 |
0.44 |
|
| 2010 |
Penela P, Murga C, Ribas C, Lafarga V, Mayor F. The complex G protein-coupled receptor kinase 2 (GRK2) interactome unveils new physiopathological targets. British Journal of Pharmacology. 160: 821-32. PMID 20590581 DOI: 10.1111/J.1476-5381.2010.00727.X |
0.532 |
|
| 2010 |
García-Hoz C, Sánchez-Fernández G, Díaz-Meco MT, Moscat J, Mayor F, Ribas C. G alpha(q) acts as an adaptor protein in protein kinase C zeta (PKCzeta)-mediated ERK5 activation by G protein-coupled receptors (GPCR). The Journal of Biological Chemistry. 285: 13480-9. PMID 20200162 DOI: 10.1074/Jbc.M109.098699 |
0.458 |
|
| 2010 |
Penela P, Rivas V, Salcedo A, Mayor F. G protein-coupled receptor kinase 2 (GRK2) modulation and cell cycle progression. Proceedings of the National Academy of Sciences of the United States of America. 107: 1118-23. PMID 20080565 DOI: 10.1073/Pnas.0905778107 |
0.499 |
|
| 2009 |
Penela P, Ribas C, Aymerich I, Mayor F. New roles of G protein-coupled receptor kinase 2 (GRK2) in cell migration. Cell Adhesion & Migration. 3: 19-23. PMID 19372742 DOI: 10.4161/Cam.3.1.7149 |
0.517 |
|
| 2008 |
Penela P, Murga C, Ribas C, Salcedo A, Jurado-Pueyo M, Rivas V, Aymerich I, Mayor F. G protein-coupled receptor kinase 2 (GRK2) in migration and inflammation. Archives of Physiology and Biochemistry. 114: 195-200. PMID 18618354 DOI: 10.1080/13813450802181039 |
0.529 |
|
| 2008 |
Jurado-Pueyo M, Campos PM, Mayor F, Murga C. GRK2-Dependent Desensitization Downstream of G Proteins Journal of Receptors and Signal Transduction. 28: 59-70. PMID 18437630 DOI: 10.1080/10799890801941939 |
0.532 |
|
| 2008 |
Penela P, Ribas C, Aymerich I, Eijkelkamp N, Barreiro O, Heijnen CJ, Kavelaars A, Sánchez-Madrid F, Mayor F. G protein-coupled receptor kinase 2 positively regulates epithelial cell migration. The Embo Journal. 27: 1206-18. PMID 18369319 DOI: 10.1038/Emboj.2008.55 |
0.499 |
|
| 2008 |
Kleibeuker W, Jurado-Pueyo M, Murga C, Eijkelkamp N, Mayor F, Heijnen CJ, Kavelaars A. Physiological changes in GRK2 regulate CCL2-induced signaling to ERK1/2 and Akt but not to MEK1/2 and calcium. Journal of Neurochemistry. 104: 979-92. PMID 17971124 DOI: 10.1111/J.1471-4159.2007.05023.X |
0.504 |
|
| 2007 |
Tutor AS, Penela P, Mayor F. Anti-beta1-adrenergic receptor autoantibodies are potent stimulators of the ERK1/2 pathway in cardiac cells. Cardiovascular Research. 76: 51-60. PMID 17628514 DOI: 10.1016/J.Cardiores.2007.05.022 |
0.352 |
|
| 2007 |
Molnar C, Holguin H, Mayor F, Ruiz-Gomez A, De Celis JF. The G protein-coupled receptor regulatory kinase GPRK2 participates in Hedgehog signaling in Drosophila Proceedings of the National Academy of Sciences of the United States of America. 104: 7963-7968. PMID 17483466 DOI: 10.1073/Pnas.0702374104 |
0.495 |
|
| 2007 |
Mayor F, Jurado-Pueyo M, Campos PM, Murga C. Interfering with MAP kinase docking interactions: implications and perspective for the p38 route. Cell Cycle (Georgetown, Tex.). 6: 528-33. PMID 17351337 DOI: 10.4161/Cc.6.5.3920 |
0.387 |
|
| 2007 |
Rey M, Valenzuela-Fernández A, Urzainqui A, Yáñez-Mó M, Pérez-Martínez M, Penela P, Mayor F, Sánchez-Madrid F. Myosin IIA is involved in the endocytosis of CXCR4 induced by SDF-1alpha. Journal of Cell Science. 120: 1126-33. PMID 17327270 DOI: 10.1242/Jcs.03415 |
0.37 |
|
| 2007 |
Ruiz-Gomez A, Mellström B, Tornero D, Morato E, Savignac M, Holguín H, Aurrekoetxea K, González P, González-García C, Ceña V, Mayor F, Naranjo JR. G protein-coupled receptor kinase 2-mediated phosphorylation of downstream regulatory element antagonist modulator regulates membrane trafficking of Kv4.2 potassium channel. The Journal of Biological Chemistry. 282: 1205-15. PMID 17102134 DOI: 10.1074/Jbc.M607166200 |
0.424 |
|
| 2007 |
Ruiz-Gómez A, Molnar C, Holguín H, Mayor F, de Celis JF. The cell biology of Smo signalling and its relationships with GPCRs Biochimica Et Biophysica Acta - Biomembranes. 1768: 901-912. PMID 17094938 DOI: 10.1016/J.Bbamem.2006.09.020 |
0.413 |
|
| 2007 |
Ribas C, Penela P, Murga C, Salcedo A, García-Hoz C, Jurado-Pueyo M, Aymerich I, Mayor F. The G protein-coupled receptor kinase (GRK) interactome: role of GRKs in GPCR regulation and signaling. Biochimica Et Biophysica Acta. 1768: 913-22. PMID 17084806 DOI: 10.1016/J.Bbamem.2006.09.019 |
0.524 |
|
| 2007 |
Cobelens PM, Kavelaars A, Heijnen CJ, Ribas C, Mayor F, Penela P. Hydrogen peroxide impairs GRK2 translation via a calpain-dependent and cdk1-mediated pathway Cellular Signalling. 19: 269-277. PMID 16963227 DOI: 10.1016/J.Cellsig.2006.06.009 |
0.43 |
|
| 2007 |
García-Hoz C, Herranz M, Díaz-Meco MT, Moscat J, Ribas C, Mayor F. PKCzeta-mediated GalphaQ stimulation of the ERK5 pathway plays a key role in cardiac hypertrophy Journal of Molecular and Cellular Cardiology. 42. DOI: 10.1016/J.Yjmcc.2007.03.127 |
0.302 |
|
| 2006 |
Peregrin S, Jurado-Pueyo M, Campos PM, Sanz-Moreno V, Ruiz-Gomez A, Crespo P, Mayor F, Murga C. Phosphorylation of p38 by GRK2 at the docking groove unveils a novel mechanism for inactivating p38MAPK. Current Biology : Cb. 16: 2042-7. PMID 17055984 DOI: 10.1016/J.Cub.2006.08.083 |
0.464 |
|
| 2006 |
Salcedo A, Mayor F, Penela P. Mdm2 is involved in the ubiquitination and degradation of G-protein-coupled receptor kinase 2. The Embo Journal. 25: 4752-62. PMID 17006543 DOI: 10.1038/Sj.Emboj.7601351 |
0.533 |
|
| 2006 |
Tutor AS, Delpón E, Caballero R, Gómez R, Núñez L, Vaquero M, Tamargo J, Mayor F, Penela P. Association of 14-3-3 proteins to beta1-adrenergic receptors modulates Kv11.1 K+ channel activity in recombinant systems. Molecular Biology of the Cell. 17: 4666-74. PMID 16914520 DOI: 10.1091/Mbc.E06-05-0422 |
0.357 |
|
| 2006 |
Mariggiò S, García-Hoz C, Sarnago S, De Blasi A, Mayor F, Ribas C. Tyrosine phosphorylation of G-protein-coupled-receptor kinase 2 (GRK2) by c-Src modulates its interaction with Galphaq. Cellular Signalling. 18: 2004-12. PMID 16725308 DOI: 10.1016/J.Cellsig.2006.03.004 |
0.516 |
|
| 2006 |
Penela P, Murga C, Ribas C, Tutor AS, Peregrín S, Mayor F. Mechanisms of regulation of G protein-coupled receptor kinases (GRKs) and cardiovascular disease. Cardiovascular Research. 69: 46-56. PMID 16288730 DOI: 10.1016/J.Cardiores.2005.09.011 |
0.488 |
|
| 2006 |
Jiménez-Sainz MC, Murga C, Kavelaars A, Jurado-Pueyo M, Krakstad BF, Heijnen CJ, Mayor F, Aragay AM. G protein-coupled receptor kinase 2 negatively regulates chemokine signaling at a level downstream from G protein subunits Molecular Biology of the Cell. 17: 25-31. PMID 16221891 DOI: 10.1091/Mbc.E05-05-0399 |
0.539 |
|
| 2004 |
Bullido MJ, Ramos MC, Ruiz-Gómez A, Tutor AS, Sastre I, Frank A, Coria F, Gil P, Mayor F, Valdivieso F. Polymorphism in genes involved in adrenergic signaling associated with Alzheimer's. Neurobiology of Aging. 25: 853-9. PMID 15212839 DOI: 10.1016/J.Neurobiolaging.2003.10.006 |
0.324 |
|
| 2004 |
Vroon A, Heijnen CJ, Lombardi MS, Cobelens PM, Mayor F, Caron MG, Kavelaars A. Reduced GRK2 level in T cells potentiates chemotaxis and signaling in response to CCL4 Journal of Leukocyte Biology. 75: 901-909. PMID 14761932 DOI: 10.1189/Jlb.0403136 |
0.574 |
|
| 2003 |
Penela P, Ribas C, Mayor F. Mechanisms of regulation of the expression and function of G protein-coupled receptor kinases. Cellular Signalling. 15: 973-81. PMID 14499340 DOI: 10.1016/S0898-6568(03)00099-8 |
0.53 |
|
| 2003 |
Jiménez-Sainz MC, Fast B, Mayor F, Aragay AM. Signaling pathways for monocyte chemoattractant protein 1-mediated extracellular signal-regulated kinase activation Molecular Pharmacology. 64: 773-782. PMID 12920215 DOI: 10.1124/Mol.64.3.773 |
0.508 |
|
| 2003 |
Sarnago S, Roca R, de Blasi A, Valencia A, Mayor F, Murga C. Involvement of intramolecular interactions in the regulation of G protein-coupled receptor kinase 2. Molecular Pharmacology. 64: 629-39. PMID 12920199 DOI: 10.1124/Mol.64.3.629 |
0.479 |
|
| 2003 |
Burgueño J, Blake DJ, Benson MA, Tinsley CL, Esapa CT, Canela EI, Penela P, Mallol J, Mayor F, Lluis C, Franco R, Ciruela F. The adenosine A2A receptor interacts with the actin-binding protein alpha-actinin. The Journal of Biological Chemistry. 278: 37545-52. PMID 12837758 DOI: 10.1074/Jbc.M302809200 |
0.451 |
|
| 2003 |
Elorza A, Penela P, Sarnago S, Mayor F. MAPK-dependent degradation of G protein-coupled receptor kinase 2. The Journal of Biological Chemistry. 278: 29164-73. PMID 12738776 DOI: 10.1074/Jbc.M304314200 |
0.526 |
|
| 2002 |
Lombardi MS, Kavelaars A, Penela P, Scholtens EJ, Roccio M, Schmidt RE, Schedlowski M, Mayor F, Heijnen CJ. Oxidative stress decreases G protein-coupled receptor kinase 2 in lymphocytes via a calpain-dependent mechanism. Molecular Pharmacology. 62: 379-88. PMID 12130691 DOI: 10.1124/Mol.62.2.379 |
0.474 |
|
| 2001 |
Penela P, Elorza A, Sarnago S, Mayor F. β‐arrestin‐ and c‐Src‐dependent degradation of G‐protein‐coupled receptor kinase 2 The Embo Journal. 20: 5129-5138. PMID 11566877 DOI: 10.1093/Emboj/20.18.5129 |
0.514 |
|
| 2001 |
Penela P, Barradas M, Álvarez-Dolado M, Muñoz A, Mayor F. Effect of hypothyroidism on G protein-coupled receptor kinase 2 expression levels in rat liver, lung, and heart. Endocrinology. 142: 987-991. PMID 11181510 DOI: 10.1210/Endo.142.3.8039 |
0.503 |
|
| 2000 |
Sefton M, Blanco MJ, Penela P, Mayor F, Nieto MA. Expression of the G protein-coupled receptor kinase 2 during early mouse embryogenesis. Mechanisms of Development. 98: 127-131. PMID 11044616 DOI: 10.1016/S0925-4773(00)00441-X |
0.449 |
|
| 2000 |
Ruiz-Gómez A, Humrich J, Murga C, Quitterer U, Lohse MJ, Mayor F. Phosphorylation of phosducin and phosducin-like protein by G protein-coupled receptor kinase 2. The Journal of Biological Chemistry. 275: 29724-30. PMID 10884381 DOI: 10.1074/Jbc.M001864200 |
0.514 |
|
| 2000 |
Penela P, Álvarez‐Dolado M, Muñoz A, Mayor F. Expression patterns of the regulatory proteins G protein-coupled receptor kinase 2 and β-arrestin 1 during rat postnatal brain development Febs Journal. 267: 4390-4396. PMID 10880962 DOI: 10.1046/J.1432-1327.2000.01484.X |
0.446 |
|
| 2000 |
Ramos-Ruiz R, Penela P, Penn RB, Mayor F. Analysis of the human G protein-coupled receptor kinase 2 (GRK2) gene promoter: regulation by signal transduction systems in aortic smooth muscle cells. Circulation. 101: 2083-9. PMID 10790351 DOI: 10.1161/01.Cir.101.17.2083 |
0.504 |
|
| 2000 |
Elorza A, Sarnago S, Mayor F. Agonist-dependent modulation of G protein-coupled receptor kinase 2 by mitogen-activated protein kinases. Molecular Pharmacology. 57: 778-783. PMID 10727525 DOI: 10.1124/Mol.57.4.778 |
0.533 |
|
| 1999 |
Sarnago S, Elorza A, Mayor F. Agonist-dependent Phosphorylation of the G Protein-coupled Receptor Kinase 2 (GRK2) by Src Tyrosine Kinase Journal of Biological Chemistry. 274: 34411-34416. PMID 10567420 DOI: 10.1074/Jbc.274.48.34411 |
0.509 |
|
| 1998 |
Mayor F, Penela P, Ruiz-Gómez A. Role of G Protein–Coupled Receptor Kinase 2 and Arrestins in β-Adrenergic Receptor Internalization Trends in Cardiovascular Medicine. 8: 234-240. PMID 14987570 DOI: 10.1016/S1050-1738(98)00008-5 |
0.49 |
|
| 1998 |
Penela P, Ruiz-Gómez A, Castaño JG, Mayor F. Degradation of the G Protein-coupled Receptor Kinase 2 by the Proteasome Pathway Journal of Biological Chemistry. 273: 35238-35244. PMID 9857063 DOI: 10.1074/Jbc.273.52.35238 |
0.529 |
|
| 1998 |
Murga C, Penela P, Zafra F, Mayor F. The subcellular and cellular distribution of G protein-coupled receptor kinase 2 in rat brain Neuroscience. 87: 631-637. PMID 9758229 DOI: 10.1016/S0306-4522(98)00145-6 |
0.532 |
|
| 1998 |
Aragay AM, Ruiz-Gómez A, Penela P, Sarnago S, Elorza A, Jiménez-Sainz MC, Mayor F. G protein-coupled receptor kinase 2 (GRK2): mechanisms of regulation and physiological functions Febs Letters. 430: 37-40. PMID 9678590 DOI: 10.1016/S0014-5793(98)00495-5 |
0.518 |
|
| 1998 |
Aragay AM, Mellado M, Frade JMR, Martin AM, Jimenez-Sainz MC, Martinez-A C, Mayor F. Monocyte chemoattractant protein-1-induced CCR2B receptor desensitization mediated by the G protein-coupled receptor kinase 2 Proceedings of the National Academy of Sciences of the United States of America. 95: 2985-2990. PMID 9501202 DOI: 10.1073/Pnas.95.6.2985 |
0.515 |
|
| 1998 |
Ozaita A, Escribá PV, Ventayol P, Murga C, Mayor F, GarcÃa-Sevilla JA. Regulation of G protein-coupled receptor kinase 2 in brains of opiate-treated rats and human opiate addicts. Journal of Neurochemistry. 70: 1249-57. PMID 9489748 DOI: 10.1046/J.1471-4159.1998.70031249.X |
0.397 |
|
| 1997 |
Murga C, Esteban N, Ruiz-Gómez A, Mayor F. The basal subcellular distribution of β‐adrenergic receptor kinase is independent of G‐protein βγ subunits Febs Letters. 409: 24-28. PMID 9199496 DOI: 10.1016/S0014-5793(97)00476-6 |
0.486 |
|
| 1997 |
Ruiz-Gómez A, Mayor F. β-Adrenergic Receptor Kinase (GRK2) Colocalizes with β-Adrenergic Receptors during Agonist-induced Receptor Internalization Journal of Biological Chemistry. 272: 9601-9604. PMID 9092483 DOI: 10.1074/Jbc.272.15.9601 |
0.494 |
|
| 1996 |
López-Barahona M, Iglesias T, García-Higuera I, Mayor F, Zaballos A, Bernal J, Muñoz A. Post-transcriptional induction of β1-adrenergic receptor by retinoic acid, but not triiodothyronine, in C6 glioma cells expressing thyroid hormone receptors European Journal of Endocrinology. 135: 709-715. PMID 9025717 DOI: 10.1530/Eje.0.1350709 |
0.32 |
|
| 1996 |
Lohse MJ, Krasel C, Winstel R, Mayor F. G-protein-coupled receptor kinases. Kidney International. 49: 1047-52. PMID 8691724 DOI: 10.1038/Ki.1996.153 |
0.521 |
|
| 1996 |
Murga C, Ruiz-Gómez A, García-Higuera I, Kim CM, Benovic JL, Mayor F. High affinity binding of beta-adrenergic receptor kinase to microsomal membranes. Modulation of the activity of bound kinase by heterotrimeric G protein activation. The Journal of Biological Chemistry. 271: 985-94. PMID 8557715 DOI: 10.1074/Jbc.271.2.985 |
0.572 |
|
| 1994 |
García-Higuera I, Mayor F. Rapid desensitization of neonatal rat liver beta-adrenergic receptors. A role for beta-adrenergic receptor kinase. Journal of Clinical Investigation. 93: 937-943. PMID 8132779 DOI: 10.1172/Jci117099 |
0.468 |
|
| 1992 |
Vaello M, Ruiz-Gómez A, Mayor F. Glycinergic ligands modulate the rate of phosphorylation of the glycine receptor by protein kinase C Biochemical and Biophysical Research Communications. 188: 813-819. PMID 1332706 DOI: 10.1016/0006-291X(92)91129-E |
0.477 |
|
| 1992 |
Garcia-Calvo M, Valdivieso F, Mayor F, Vázquez J. Sensitive procedures for measuring chloride fluxes mediated by the purified glycine receptor incorporated into phospholipid vesicles. Neuroscience Letters. 136: 102-104. PMID 1321962 DOI: 10.1016/0304-3940(92)90658-T |
0.372 |
|
| 1992 |
Garcia-Higuera I, Mayor F. Rapid agonist-induced beta-adrenergic receptor kinase translocation in C6 glioma cells. Febs Letters. 302: 61-64. PMID 1316849 DOI: 10.1016/0014-5793(92)80285-O |
0.503 |
|
| 1991 |
Ruiz‐Gómez A, Fernández‐Shaw C, Morato E, Marvizón JCG, Vázquez J, Valdivieso F, Mayor F. Sulfhydryl Groups Modulate the Allosteric Interaction Between Glycine Binding Sites at the Inhibitory Glycine Receptor Journal of Neurochemistry. 56: 1690-1697. PMID 1849551 DOI: 10.1111/J.1471-4159.1991.Tb02069.X |
0.338 |
|
| 1990 |
Ruiz-Gomez A, Morato E, Garcia-Calvo M, Valdivieso F, Mayor F. Localization of the strychnine binding site on the 48-kilodalton subunit of the glycine receptor. Biochemistry. 29: 7033-7040. PMID 2171639 DOI: 10.1021/Bi00482A012 |
0.325 |
|
| 1989 |
Garcia-Calvo M, Ruiz-Gomez A, Vazquez J, Morato E, Valdivieso F, Mayor F. Functional reconstitution of the glycine receptor. Biochemistry. 28: 6405-6409. PMID 2551372 DOI: 10.1021/Bi00441A037 |
0.387 |
|
| 1989 |
Ruiz‐Gómez A, García‐Calvo M, Vázquez J, Marvizón JCG, Valdivieso F, Mayor F. Thermodynamics of agonist and antagonist interaction with the strychnine-sensitive glycine receptor. Journal of Neurochemistry. 52: 1775-1780. PMID 2542450 DOI: 10.1111/J.1471-4159.1989.Tb07256.X |
0.356 |
|
| 1989 |
Gómez AR, Fernández-Shaw C, Valdivieso F, Mayor F. Chemical modification of the glycine receptor with fluorescein isothiocyanate specifically affects the interaction of glycine with its binding site Biochemical and Biophysical Research Communications. 160: 374-381. PMID 2540750 DOI: 10.1016/0006-291X(89)91666-5 |
0.333 |
|
| 1986 |
Benovic JL, Mayor F, Somers RL, Caron MG, Lefkowitz RJ. Light-dependent phosphorylation of rhodopsin by β-adrenergic receptor kinase Nature. 321: 869-872. PMID 3014340 DOI: 10.1038/321869A0 |
0.712 |
|
| 1976 |
Moreno FJ, Benito M, Sánchez-Medina F, Medina JM, Mayor F. Pyruvate kinase activity and gluconeogenesis in rat liver after glycogen depletion with nicotinic acid. Molecular and Cellular Biochemistry. 13: 89-93. PMID 1004500 DOI: 10.1007/Bf01837058 |
0.313 |
|
| 1975 |
Moreno FJ, Sánchez-Urrutia L, Medina JM, Sánchez-Medina F, Mayor F. Stimulation of phosphoenolpyruvate carboxykinase (guanosine triphosphate) activity by low concentrations of circulating glucose in perfused rat liver. Biochemical Journal. 150: 51-58. PMID 173301 DOI: 10.1042/Bj1500051 |
0.302 |
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