| Year |
Citation |
Score |
| 2024 |
Plasil SL, Farris SP, Blednov Y, Mayfield RD, Mangieri RA, Nwokeji UJ, Aziz HC, Lambeth PS, Harris RA, Homanics GE. Mutation of novel ethanol-responsive lncRNA Gm41261 impacts ethanol-related behavioral responses in mice. Genes, Brain, and Behavior. 23: e12886. PMID 38373108 DOI: 10.1111/gbb.12886 |
0.379 |
|
| 2020 |
Blednov YA, Borghese CM, Dugan MP, Pradhan S, Thodati TM, Kichili NR, Harris RA, Messing RO. Apremilast regulates acute effects of ethanol and other GABAergic drugs via protein kinase A-dependent signaling. Neuropharmacology. 108220. PMID 32736086 DOI: 10.1016/J.Neuropharm.2020.108220 |
0.418 |
|
| 2020 |
Blednov YA, Da Costa A, Mayfield J, Harris RA, Messing RO. Deletion of Tlr3 reduces acute tolerance to alcohol and alcohol consumption in the intermittent access procedure in male mice. Addiction Biology. e12932. PMID 32604471 DOI: 10.1111/Adb.12932 |
0.395 |
|
| 2020 |
Warden AS, Triplett TA, Lyu A, Grantham EK, Azzam MM, DaCosta A, Mason S, Blednov YA, Ehrlich LIR, Mayfield RD, Harris RA. Microglia depletion and alcohol: Transcriptome and behavioral profiles. Addiction Biology. e12889. PMID 32176824 DOI: 10.1111/Adb.12889 |
0.363 |
|
| 2019 |
Erickson EK, Blednov YA, Harris RA, Mayfield RD. Glial gene networks associated with alcohol dependence. Scientific Reports. 9: 10949. PMID 31358844 DOI: 10.1038/S41598-019-47454-4 |
0.368 |
|
| 2019 |
Chung T, Harris RA. Cannabis and Alcohol: From Basic Science to Public Policy. Alcoholism, Clinical and Experimental Research. PMID 31265135 DOI: 10.1111/Acer.14144 |
0.322 |
|
| 2019 |
Blednov YA, Bajo M, Roberts AJ, Da Costa AJ, Black M, Edmunds S, Mayfield J, Roberto M, Homanics GE, Lasek AW, Hitzemann RJ, Harris RA. Scn4b regulates the hypnotic effects of ethanol and other sedative drugs. Genes, Brain, and Behavior. e12562. PMID 30817077 DOI: 10.1111/Gbb.12562 |
0.322 |
|
| 2018 |
Warden AS, Azzam M, DaCosta A, Mason S, Blednov YA, Messing RO, Mayfield RD, Harris RA. Toll-like receptor 3 activation increases voluntary alcohol intake in C57BL/6J male mice. Brain, Behavior, and Immunity. PMID 30550931 DOI: 10.1016/J.Bbi.2018.12.004 |
0.391 |
|
| 2018 |
Warden AS, Azzam MM, DaCosta A, Mason S, Blednov YA, Messing RO, Mayfield RD, Harris RA. Toll-like receptor 3 dynamics in female C57BL/6J mice: Regulation of alcohol intake. Brain, Behavior, and Immunity. PMID 30550930 DOI: 10.1016/J.Bbi.2018.12.006 |
0.376 |
|
| 2018 |
Wolfe SA, Farris SP, Mayfield JE, Heaney CF, Erickson EK, Harris RA, Mayfield RD, Raab-Graham KF. Ethanol and a rapid-acting antidepressant produce overlapping changes in exon expression in the synaptic transcriptome. Neuropharmacology. PMID 30419244 DOI: 10.1016/J.Neuropharm.2018.11.007 |
0.414 |
|
| 2018 |
Ferguson LB, Zhang L, Wang S, Bridges C, Harris RA, Ponomarev I. Peroxisome Proliferator Activated Receptor Agonists Modulate Transposable Element Expression in Brain and Liver. Frontiers in Molecular Neuroscience. 11: 331. PMID 30283300 DOI: 10.3389/Fnmol.2018.00331 |
0.327 |
|
| 2018 |
Ferguson LB, Zhang L, Kircher D, Wang S, Mayfield RD, Crabbe JC, Morrisett RA, Harris RA, Ponomarev I. Dissecting Brain Networks Underlying Alcohol Binge Drinking Using a Systems Genomics Approach. Molecular Neurobiology. PMID 30062672 DOI: 10.1007/S12035-018-1252-0 |
0.375 |
|
| 2018 |
Most D, Salem NA, Tiwari GR, Blednov YA, Mayfield RD, Harris RA. Silencing synaptic MicroRNA-411 reduces voluntary alcohol consumption in mice. Addiction Biology. PMID 29665166 DOI: 10.1111/Adb.12625 |
0.359 |
|
| 2018 |
Blednov YA, Da Costa AJ, Tarbox T, Ponomareva O, Messing RO, Harris RA. Apremilast Alters Behavioral Responses to Ethanol in Mice: I. Reduced Ethanol Consumption and Preference. Alcoholism, Clinical and Experimental Research. PMID 29469962 DOI: 10.1111/Acer.13616 |
0.387 |
|
| 2018 |
Blednov YA, Da Costa AJ, Harris RA, Messing RO. Apremilast Alters Behavioral Responses to Ethanol in Mice: II. Increased Sedation, Intoxication and Reduced Acute Functional Tolerance. Alcoholism, Clinical and Experimental Research. PMID 29469954 DOI: 10.1111/Acer.13615 |
0.391 |
|
| 2018 |
Osterndorff-Kahanek EA, Tiwari GR, Lopez MF, Becker HC, Harris RA, Mayfield RD. Long-term ethanol exposure: Temporal pattern of microRNA expression and associated mRNA gene networks in mouse brain. Plos One. 13: e0190841. PMID 29315347 DOI: 10.1371/Journal.Pone.0190841 |
0.308 |
|
| 2018 |
Erickson EK, Farris SP, Blednov YA, Mayfield RD, Harris RA. Astrocyte-specific transcriptome responses to chronic ethanol consumption. The Pharmacogenomics Journal. PMID 29305589 DOI: 10.1038/S41397-017-0012-2 |
0.398 |
|
| 2017 |
Ferguson LB, Ozburn AR, Ponomarev I, Metten P, Reilly M, Crabbe JC, Harris RA, Mayfield RD. Genome-Wide Expression Profiles Drive Discovery of Novel Compounds that Reduce Binge Drinking in Mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29251283 DOI: 10.1038/Npp.2017.301 |
0.365 |
|
| 2017 |
McCarthy GM, Farris SP, Blednov YA, Harris RA, Mayfield RD. Microglial-specific transcriptome changes following chronic alcohol consumption. Neuropharmacology. PMID 29101021 DOI: 10.1016/J.Neuropharm.2017.10.035 |
0.406 |
|
| 2017 |
Tarvin RD, Borghese CM, Sachs W, Santos JC, Lu Y, O'Connell LA, Cannatella DC, Harris RA, Zakon HH. Interacting amino acid replacements allow poison frogs to evolve epibatidine resistance. Science (New York, N.Y.). 357: 1261-1266. PMID 28935799 DOI: 10.1126/Science.Aan5061 |
0.307 |
|
| 2017 |
McCracken LM, Lowes DC, Salling MC, Carreau-Vollmer C, Odean NN, Blednov YA, Betz H, Harris RA, Harrison NL. Glycine receptor α3 and α2 subunits mediate tonic and exogenous agonist-induced currents in forebrain. Proceedings of the National Academy of Sciences of the United States of America. PMID 28784756 DOI: 10.1073/Pnas.1703839114 |
0.307 |
|
| 2017 |
Borghese CM, Herman M, Snell LD, Lawrence KJ, Lee HY, Backos DS, Vanderlinden LA, Harris RA, Roberto M, Hoffman PL, Tabakoff B. Novel Molecule Exhibiting Selective Affinity for GABAA Receptor Subtypes. Scientific Reports. 7: 6230. PMID 28740086 DOI: 10.1038/S41598-017-05966-X |
0.433 |
|
| 2017 |
Harris RA, Koob GF. The future is now: A 2020 view of alcoholism research. Neuropharmacology. 122: 1-2. PMID 28633760 DOI: 10.1016/J.Neuropharm.2017.06.001 |
0.314 |
|
| 2017 |
Blednov YA, Borghese CM, Ruiz CI, Cullins MA, Da Costa A, Osterndorff-Kahanek EA, Homanics GE, Harris RA. Mutation of the inhibitory ethanol site in GABAA ρ1 receptors promotes tolerance to ethanol-induced motor incoordination. Neuropharmacology. PMID 28623169 DOI: 10.1016/J.Neuropharm.2017.06.013 |
0.476 |
|
| 2017 |
Ponomarev I, Stelly CE, Morikawa H, Blednov YA, Mayfield RD, Harris RA. Mechanistic insights into epigenetic modulation of ethanol consumption. Alcohol (Fayetteville, N.Y.). PMID 28433417 DOI: 10.1016/J.Alcohol.2017.01.016 |
0.414 |
|
| 2017 |
Blednov YA, Black M, Benavidez JM, Da Costa A, Mayfield J, Harris RA. Sedative and Motor Incoordination Effects of Ethanol in Mice Lacking CD14, TLR2, TLR4, or MyD88. Alcoholism, Clinical and Experimental Research. PMID 28160299 DOI: 10.1111/Acer.13314 |
0.393 |
|
| 2017 |
Blednov YA, Black M, Chernis J, Da Costa A, Mayfield J, Harris RA. Ethanol Consumption in Mice Lacking CD14, TLR2, TLR4, or MyD88. Alcoholism, Clinical and Experimental Research. PMID 28146272 DOI: 10.1111/Acer.13316 |
0.382 |
|
| 2017 |
Warden AS, DaCosta A, Blednov YA, Mayfield RD, Harris RA. TLR3 activation increases voluntary alcohol consumption Alcohol. 60: 242. DOI: 10.1016/J.Alcohol.2017.02.348 |
0.336 |
|
| 2017 |
Harris RA, Warden AS, Mayfield RD, Blednov YA. Neuroimmune regulation of alcohol consumption Alcohol. 60: 220-221. DOI: 10.1016/J.Alcohol.2017.02.259 |
0.342 |
|
| 2016 |
Harris RA, Bajo M, Bell RL, Blednov YA, Varodayan FP, Truitt J, de Guglielmo G, Lasek AW, Logrip ML, Vendruscolo LF, Roberts AJ, Roberts E, George O, Mayfield J, Billiar TR, et al. Genetic and pharmacologic manipulation of TLR4 has minimal impact on ethanol consumption in rodents. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 27986929 DOI: 10.1523/Jneurosci.2002-16.2016 |
0.435 |
|
| 2016 |
Warden A, Erickson E, Robinson G, Harris RA, Mayfield RD. The neuroimmune transcriptome and alcohol dependence: potential for targeted therapies. Pharmacogenomics. PMID 27918243 DOI: 10.2217/Pgs-2016-0062 |
0.372 |
|
| 2016 |
Tulisiak CT, Harris RA, Ponomarev I. DNA modifications in models of alcohol use disorders. Alcohol (Fayetteville, N.Y.). PMID 27865607 DOI: 10.1016/J.Alcohol.2016.11.004 |
0.328 |
|
| 2016 |
Truitt JM, Blednov YA, Benavidez JM, Black M, Ponomareva O, Law J, Merriman M, Horani S, Jameson K, Lasek AW, Harris RA, Mayfield RD. Inhibition of IKKβ Reduces Ethanol Consumption in C57BL/6J Mice. Eneuro. 3. PMID 27822501 DOI: 10.1523/ENEURO.0256-16.2016 |
0.318 |
|
| 2016 |
Wolfe SA, Workman ER, Heaney CF, Niere F, Namjoshi S, Cacheaux LP, Farris SP, Drew MR, Zemelman BV, Harris RA, Raab-Graham KF. FMRP regulates an ethanol-dependent shift in GABABR function and expression with rapid antidepressant properties. Nature Communications. 7: 12867. PMID 27666021 DOI: 10.1038/Ncomms12867 |
0.438 |
|
| 2016 |
McCracken ML, Gorini G, McCracken LM, Mayfield RD, Harris RA, Trudell JR. Inter- and Intra-Subunit Butanol/Isoflurane Sites of Action in the Human Glycine Receptor. Frontiers in Molecular Neuroscience. 9: 45. PMID 27378846 DOI: 10.3389/Fnmol.2016.00045 |
0.361 |
|
| 2016 |
Blednov YA, Black M, Benavidez JM, Stamatakis EE, Harris RA. PPAR Agonists: I. Role of Receptor Subunits in Alcohol Consumption in Male and Female Mice. Alcoholism, Clinical and Experimental Research. PMID 26857685 DOI: 10.1111/Acer.12976 |
0.302 |
|
| 2016 |
Blednov YA, Black M, Benavidez JM, Stamatakis EE, Harris RA. PPAR Agonists: II. Fenofibrate and Tesaglitazar Alter Behaviors Related to Voluntary Alcohol Consumption. Alcoholism, Clinical and Experimental Research. PMID 26857541 DOI: 10.1111/Acer.12972 |
0.431 |
|
| 2016 |
Trudell JR, Borghese CM, Ruiz CI, Lee US, Cullins MA, Bertaccini EJ, Harris RA. Identification of an Inhibitory Alcohol Binding Site in GABAaRho1 Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.2311 |
0.44 |
|
| 2015 |
Borghese CM, Ruiz CI, Lee US, Cullins MA, Bertaccini EJ, Trudell JR, Harris RA. Identification of an Inhibitory Alcohol Binding Site in GABAA ρ1 Receptors. Acs Chemical Neuroscience. PMID 26571107 DOI: 10.1021/Acschemneuro.5B00246 |
0.433 |
|
| 2015 |
Most D, Leiter C, Blednov YA, Harris RA, Mayfield RD. Synaptic microRNAs Coordinately Regulate Synaptic mRNAs: Perturbation by Chronic Alcohol Consumption. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26105134 DOI: 10.1038/Npp.2015.179 |
0.342 |
|
| 2015 |
Cui C, Noronha A, Warren KR, Koob GF, Sinha R, Thakkar M, Matochik J, Crews FT, Chandler LJ, Pfefferbaum A, Becker HC, Lovinger D, Everitt BJ, Egli M, Mandyam CD, ... ... Harris RA, et al. Brain pathways to recovery from alcohol dependence. Alcohol (Fayetteville, N.Y.). 49: 435-52. PMID 26074423 DOI: 10.1016/J.Alcohol.2015.04.006 |
0.317 |
|
| 2015 |
Horani S, Stater EP, Corringer PJ, Trudell JR, Harris RA, Howard RJ. Ethanol Modulation is Quantitatively Determined by the Transmembrane Domain of Human α1 Glycine Receptors. Alcoholism, Clinical and Experimental Research. 39: 962-8. PMID 25973519 DOI: 10.1111/Acer.12735 |
0.394 |
|
| 2015 |
Farris SP, Pietrzykowski AZ, Miles MF, O'Brien MA, Sanna PP, Zakhari S, Mayfield RD, Harris RA. Applying the new genomics to alcohol dependence. Alcohol (Fayetteville, N.Y.). PMID 25896098 DOI: 10.1016/J.Alcohol.2015.03.001 |
0.321 |
|
| 2015 |
Blednov YA, Benavidez JM, Black M, Mayfield J, Harris RA. Role of interleukin-1 receptor signaling in the behavioral effects of ethanol and benzodiazepines. Neuropharmacology. 95: 309-20. PMID 25839897 DOI: 10.1016/J.Neuropharm.2015.03.015 |
0.443 |
|
| 2015 |
Osterndorff-Kahanek EA, Becker HC, Lopez MF, Farris SP, Tiwari GR, Nunez YO, Harris RA, Mayfield RD. Chronic ethanol exposure produces time- and brain region-dependent changes in gene coexpression networks. Plos One. 10: e0121522. PMID 25803291 DOI: 10.1371/Journal.Pone.0121522 |
0.361 |
|
| 2015 |
Blednov YA, Benavidez JM, Black M, Leiter CR, Osterndorff-Kahanek E, Harris RA. Glycine receptors containing α2 or α3 subunits regulate specific ethanol-mediated behaviors. The Journal of Pharmacology and Experimental Therapeutics. 353: 181-91. PMID 25678534 DOI: 10.1124/Jpet.114.221895 |
0.497 |
|
| 2015 |
Blednov YA, Benavidez JM, Black M, Ferguson LB, Schoenhard GL, Goate AM, Edenberg HJ, Wetherill L, Hesselbrock V, Foroud T, Harris RA. Peroxisome proliferator-activated receptors α and γ are linked with alcohol consumption in mice and withdrawal and dependence in humans. Alcoholism, Clinical and Experimental Research. 39: 136-45. PMID 25516156 DOI: 10.1111/Acer.12610 |
0.437 |
|
| 2014 |
Most D, Ferguson L, Harris RA. Molecular basis of alcoholism. Handbook of Clinical Neurology. 125: 89-111. PMID 25307570 DOI: 10.1016/B978-0-444-62619-6.00006-9 |
0.342 |
|
| 2014 |
Robinson G, Most D, Ferguson LB, Mayfield J, Harris RA, Blednov YA. Neuroimmune pathways in alcohol consumption: evidence from behavioral and genetic studies in rodents and humans. International Review of Neurobiology. 118: 13-39. PMID 25175860 DOI: 10.1016/B978-0-12-801284-0.00002-6 |
0.382 |
|
| 2014 |
Ferguson LB, Most D, Blednov YA, Harris RA. PPAR agonists regulate brain gene expression: relationship to their effects on ethanol consumption. Neuropharmacology. 86: 397-407. PMID 25036611 DOI: 10.1016/J.Neuropharm.2014.06.024 |
0.434 |
|
| 2014 |
Blednov YA, Benavidez JM, Black M, Harris RA. Inhibition of phosphodiesterase 4 reduces ethanol intake and preference in C57BL/6J mice. Frontiers in Neuroscience. 8: 129. PMID 24904269 DOI: 10.3389/Fnins.2014.00129 |
0.421 |
|
| 2014 |
Trudell JR, Messing RO, Mayfield J, Harris RA. Alcohol dependence: molecular and behavioral evidence. Trends in Pharmacological Sciences. 35: 317-23. PMID 24865944 DOI: 10.1016/J.Tips.2014.04.009 |
0.386 |
|
| 2014 |
Bajo M, Madamba SG, Roberto M, Blednov YA, Sagi VN, Roberts E, Rice KC, Harris RA, Siggins GR. Innate immune factors modulate ethanol interaction with GABAergic transmission in mouse central amygdala. Brain, Behavior, and Immunity. 40: 191-202. PMID 24675033 DOI: 10.1016/J.Bbi.2014.03.007 |
0.39 |
|
| 2014 |
Howard RJ, Trudell JR, Harris RA. Seeking structural specificity: direct modulation of pentameric ligand-gated ion channels by alcohols and general anesthetics. Pharmacological Reviews. 66: 396-412. PMID 24515646 DOI: 10.1124/Pr.113.007468 |
0.327 |
|
| 2014 |
Blednov YA, Benavidez JM, Black M, Leiter CR, Osterndorff-Kahanek E, Johnson D, Borghese CM, Hanrahan JR, Johnston GA, Chebib M, Harris RA. GABAA receptors containing ρ1 subunits contribute to in vivo effects of ethanol in mice. Plos One. 9: e85525. PMID 24454882 DOI: 10.1371/Journal.Pone.0085525 |
0.596 |
|
| 2014 |
Lee C, Mayfield RD, Harris RA. Altered gamma-aminobutyric acid type B receptor subunit 1 splicing in alcoholics. Biological Psychiatry. 75: 765-73. PMID 24209778 DOI: 10.1016/J.Biopsych.2013.08.028 |
0.416 |
|
| 2014 |
Borghese CM, Hicks JA, Lapid DJ, Trudell JR, Harris RA. GABA(A) receptor transmembrane amino acids are critical for alcohol action: disulfide cross-linking and alkyl methanethiosulfonate labeling reveal relative location of binding sites. Journal of Neurochemistry. 128: 363-75. PMID 24117469 DOI: 10.1111/Jnc.12476 |
0.4 |
|
| 2014 |
Gorini G, Harris RA, Mayfield RD. Proteomic approaches and identification of novel therapeutic targets for alcoholism. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 104-30. PMID 23900301 DOI: 10.1038/Npp.2013.182 |
0.312 |
|
| 2013 |
Ferguson C, McKay M, Harris RA, Homanics GE. Toll-like receptor 4 (Tlr4) knockout rats produced by transcriptional activator-like effector nuclease (TALEN)-mediated gene inactivation. Alcohol (Fayetteville, N.Y.). 47: 595-9. PMID 24199847 DOI: 10.1016/J.Alcohol.2013.09.043 |
0.341 |
|
| 2013 |
Heusser SA, Howard RJ, Borghese CM, Cullins MA, Broemstrup T, Lee US, Lindahl E, Carlsson J, Harris RA. Functional validation of virtual screening for novel agents with general anesthetic action at ligand-gated ion channels. Molecular Pharmacology. 84: 670-8. PMID 23950219 DOI: 10.1124/Mol.113.087692 |
0.358 |
|
| 2013 |
McCracken LM, Trudell JR, McCracken ML, Harris RA. Zinc-dependent modulation of α2- and α3-glycine receptor subunits by ethanol. Alcoholism, Clinical and Experimental Research. 37: 2002-10. PMID 23895467 DOI: 10.1111/Acer.12192 |
0.439 |
|
| 2013 |
Sauguet L, Howard RJ, Malherbe L, Lee US, Corringer PJ, Harris RA, Delarue M. Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel. Nature Communications. 4: 1697. PMID 23591864 DOI: 10.1038/Ncomms2682 |
0.482 |
|
| 2013 |
Osterndorff-Kahanek E, Ponomarev I, Blednov YA, Harris RA. Gene expression in brain and liver produced by three different regimens of alcohol consumption in mice: comparison with immune activation. Plos One. 8: e59870. PMID 23555817 DOI: 10.1371/Journal.Pone.0059870 |
0.367 |
|
| 2013 |
Mayfield J, Ferguson L, Harris RA. Neuroimmune signaling: a key component of alcohol abuse. Current Opinion in Neurobiology. 23: 513-20. PMID 23434064 DOI: 10.1016/J.Conb.2013.01.024 |
0.375 |
|
| 2013 |
Ozburn AR, Harris RA, Blednov YA. Chronic voluntary alcohol consumption results in tolerance to sedative/hypnotic and hypothermic effects of alcohol in hybrid mice. Pharmacology, Biochemistry, and Behavior. 104: 33-9. PMID 23313769 DOI: 10.1016/J.Pbb.2012.12.025 |
0.429 |
|
| 2013 |
McCracken LM, Blednov YA, Trudell JR, Benavidez JM, Betz H, Harris RA. Mutation of a zinc-binding residue in the glycine receptor α1 subunit changes ethanol sensitivity in vitro and alcohol consumption in vivo. The Journal of Pharmacology and Experimental Therapeutics. 344: 489-500. PMID 23230213 DOI: 10.1124/Jpet.112.197707 |
0.452 |
|
| 2013 |
Blednov YA, Benavidez JM, Black M, Chandra D, Homanics GE, Rudolph U, Harris RA. Linking GABA(A) receptor subunits to alcohol-induced conditioned taste aversion and recovery from acute alcohol intoxication. Neuropharmacology. 67: 46-56. PMID 23147414 DOI: 10.1016/J.Neuropharm.2012.10.016 |
0.337 |
|
| 2013 |
Howard RJ, Sauguet L, Broemstrup T, Murail S, Lee US, Horani S, Trudell JR, Corringer P, Lindahl E, Delarue M, Harris RA. Alcohol and Anesthetic Binding to Pentameric Ligand-Gated Ion Channels Revealed in a Prokaryotic Model System Biophysical Journal. 104: 635a-636a. DOI: 10.1016/J.Bpj.2012.11.3512 |
0.319 |
|
| 2013 |
Sauguet L, Howard R, Malherbe L, Lee US, Corringer P, Harris RA, Delarue M. X-Ray Structures of an Interfacial Potentiating Site for Alcohols and Anesthetics in a Pentameric Ligand-Gated Ion Channel Biophysical Journal. 104: 208a. DOI: 10.1016/J.Bpj.2012.11.1175 |
0.468 |
|
| 2012 |
Murail S, Howard RJ, Broemstrup T, Bertaccini EJ, Harris RA, Trudell JR, Lindahl E. Molecular mechanism for the dual alcohol modulation of Cys-loop receptors. Plos Computational Biology. 8: e1002710. PMID 23055913 DOI: 10.1371/Journal.Pcbi.1002710 |
0.5 |
|
| 2012 |
Borghese CM, Xiong W, Oh SI, Ho A, Mihic SJ, Zhang L, Lovinger DM, Homanics GE, Eger EI, Harris RA. Mutations M287L and Q266I in the glycine receptor α1 subunit change sensitivity to volatile anesthetics in oocytes and neurons, but not the minimal alveolar concentration in knockin mice. Anesthesiology. 117: 765-71. PMID 22885675 DOI: 10.1097/Aln.0B013E31826A0D93 |
0.388 |
|
| 2012 |
Ponomarev I, Wang S, Zhang L, Harris RA, Mayfield RD. Gene coexpression networks in human brain identify epigenetic modifications in alcohol dependence. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 1884-97. PMID 22302827 DOI: 10.1523/Jneurosci.3136-11.2012 |
0.362 |
|
| 2012 |
Johnson WD, Howard RJ, Trudell JR, Harris RA. The TM2 6' position of GABA(A) receptors mediates alcohol inhibition. The Journal of Pharmacology and Experimental Therapeutics. 340: 445-56. PMID 22072732 DOI: 10.1124/Jpet.111.188037 |
0.421 |
|
| 2012 |
Blednov YA, Benavidez JM, Homanics GE, Harris RA. Behavioral characterization of knockin mice with mutations M287L and Q266I in the glycine receptor α1 subunit. The Journal of Pharmacology and Experimental Therapeutics. 340: 317-29. PMID 22037202 DOI: 10.1124/Jpet.111.185124 |
0.41 |
|
| 2012 |
Borghese CM, Blednov YA, Quan Y, Iyer SV, Xiong W, Mihic SJ, Zhang L, Lovinger DM, Trudell JR, Homanics GE, Harris RA. Characterization of two mutations, M287L and Q266I, in the α1 glycine receptor subunit that modify sensitivity to alcohols. The Journal of Pharmacology and Experimental Therapeutics. 340: 304-16. PMID 22037201 DOI: 10.1124/Jpet.111.185116 |
0.462 |
|
| 2012 |
Blednov YA, Ponomarev I, Geil C, Bergeson S, Koob GF, Harris RA. Neuroimmune regulation of alcohol consumption: behavioral validation of genes obtained from genomic studies. Addiction Biology. 17: 108-20. PMID 21309947 DOI: 10.1111/J.1369-1600.2010.00284.X |
0.429 |
|
| 2011 |
Howard RJ, Murail S, Ondricek KE, Corringer PJ, Lindahl E, Trudell JR, Harris RA. Structural basis for alcohol modulation of a pentameric ligand-gated ion channel. Proceedings of the National Academy of Sciences of the United States of America. 108: 12149-54. PMID 21730162 DOI: 10.1073/Pnas.1104480108 |
0.412 |
|
| 2011 |
Howard RJ, Slesinger PA, Davies DL, Das J, Trudell JR, Harris RA. Alcohol-binding sites in distinct brain proteins: the quest for atomic level resolution. Alcoholism, Clinical and Experimental Research. 35: 1561-73. PMID 21676006 DOI: 10.1111/J.1530-0277.2011.01502.X |
0.439 |
|
| 2011 |
Morikawa H, Harris RA. Small K channels: big targets for treating alcoholism? Biological Psychiatry. 69: 614-5. PMID 21397742 DOI: 10.1016/J.Biopsych.2011.01.016 |
0.421 |
|
| 2011 |
Crabbe JC, Harris RA, Koob GF. Preclinical studies of alcohol binge drinking. Annals of the New York Academy of Sciences. 1216: 24-40. PMID 21272009 DOI: 10.1111/J.1749-6632.2010.05895.X |
0.344 |
|
| 2011 |
Mulligan MK, Rhodes JS, Crabbe JC, Mayfield RD, Harris RA, Ponomarev I. Molecular profiles of drinking alcohol to intoxication in C57BL/6J mice. Alcoholism, Clinical and Experimental Research. 35: 659-70. PMID 21223303 DOI: 10.1111/J.1530-0277.2010.01384.X |
0.374 |
|
| 2011 |
Blednov YA, Borghese CM, McCracken ML, Benavidez JM, Geil CR, Osterndorff-Kahanek E, Werner DF, Iyer S, Swihart A, Harrison NL, Homanics GE, Harris RA. Loss of ethanol conditioned taste aversion and motor stimulation in knockin mice with ethanol-insensitive α2-containing GABA(A) receptors. The Journal of Pharmacology and Experimental Therapeutics. 336: 145-54. PMID 20876231 DOI: 10.1124/Jpet.110.171645 |
0.356 |
|
| 2011 |
Howard RJ, Ondricek KE, Trudell JR, Harris RA. Structural Basis for Alcohol Modulation of a Ligand-Gated Ion Channel Homolog Biophysical Journal. 100: 101a. DOI: 10.1016/J.Bpj.2010.12.756 |
0.408 |
|
| 2010 |
Lee C, Mayfield RD, Harris RA. Intron 4 containing novel GABAB1 isoforms impair GABAB receptor function. Plos One. 5: e14044. PMID 21124972 DOI: 10.1371/Journal.Pone.0014044 |
0.34 |
|
| 2010 |
McCracken ML, Borghese CM, Trudell JR, Harris RA. A transmembrane amino acid in the GABAA receptor β2 subunit critical for the actions of alcohols and anesthetics. The Journal of Pharmacology and Experimental Therapeutics. 335: 600-6. PMID 20826568 DOI: 10.1124/Jpet.110.170472 |
0.435 |
|
| 2010 |
McCracken LM, Trudell JR, Goldstein BE, Harris RA, Mihic SJ. Zinc enhances ethanol modulation of the alpha1 glycine receptor. Neuropharmacology. 58: 676-81. PMID 19913039 DOI: 10.1016/J.Neuropharm.2009.11.001 |
0.52 |
|
| 2009 |
Etheridge N, Lewohl JM, Mayfield RD, Harris RA, Dodd PR. Synaptic proteome changes in the superior frontal gyrus and occipital cortex of the alcoholic brain. Proteomics. Clinical Applications. 3: 730-742. PMID 19924264 DOI: 10.1002/Prca.200800202 |
0.354 |
|
| 2009 |
Mayfield RD, Harris RA. Gene expression profiling in blood: new diagnostics in alcoholism and addiction? Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 250-1. PMID 19079075 DOI: 10.1038/Npp.2008.162 |
0.329 |
|
| 2008 |
Horishita T, Eger EI, Harris RA. The effects of volatile aromatic anesthetics on voltage-gated Na+ channels expressed in Xenopus oocytes. Anesthesia and Analgesia. 107: 1579-86. PMID 18931215 DOI: 10.1213/Ane.0B013E318184B966 |
0.338 |
|
| 2008 |
Jenkins A, Lobo IA, Gong D, Trudell JR, Solt K, Harris RA, Eger EI. General anesthetics have additive actions on three ligand gated ion channels. Anesthesia and Analgesia. 107: 486-93. PMID 18633027 DOI: 10.1213/Ane.0B013E31817B70C1 |
0.362 |
|
| 2008 |
Harris RA, Trudell JR, Mihic SJ. Ethanol's molecular targets. Science Signaling. 1: re7. PMID 18632551 DOI: 10.1126/Scisignal.128Re7 |
0.455 |
|
| 2008 |
Ozburn AR, Harris RA, Blednov YA. Wheel running, voluntary ethanol consumption, and hedonic substitution. Alcohol (Fayetteville, N.Y.). 42: 417-24. PMID 18579336 DOI: 10.1016/J.Alcohol.2008.04.006 |
0.439 |
|
| 2008 |
Horishita T, Harris RA. n-Alcohols inhibit voltage-gated Na+ channels expressed in Xenopus oocytes. The Journal of Pharmacology and Experimental Therapeutics. 326: 270-7. PMID 18434586 DOI: 10.1124/Jpet.108.138370 |
0.382 |
|
| 2008 |
Lobo IA, Harris RA. GABA(A) receptors and alcohol. Pharmacology, Biochemistry, and Behavior. 90: 90-4. PMID 18423561 DOI: 10.1016/J.Pbb.2008.03.006 |
0.48 |
|
| 2008 |
Blednov YA, Harris RA. Metabotropic glutamate receptor 5 (mGluR5) regulation of ethanol sedation, dependence and consumption: relationship to acamprosate actions. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 11: 775-93. PMID 18377703 DOI: 10.1017/S1461145708008584 |
0.463 |
|
| 2008 |
Reilly MT, Lobo IA, McCracken LM, Borghese CM, Gong D, Horishita T, Harris RA. Effects of acamprosate on neuronal receptors and ion channels expressed in Xenopus oocytes. Alcoholism, Clinical and Experimental Research. 32: 188-96. PMID 18226119 DOI: 10.1111/J.1530-0277.2007.00569.X |
0.412 |
|
| 2008 |
Lobo IA, Harris RA, Trudell JR. Cross-linking of sites involved with alcohol action between transmembrane segments 1 and 3 of the glycine receptor following activation. Journal of Neurochemistry. 104: 1649-62. PMID 18036150 DOI: 10.1111/J.1471-4159.2007.05090.X |
0.383 |
|
| 2007 |
Okvist A, Johansson S, Kuzmin A, Bazov I, Merino-Martinez R, Ponomarev I, Mayfield RD, Harris RA, Sheedy D, Garrick T, Harper C, Hurd YL, Terenius L, Ekström TJ, Bakalkin G, et al. Neuroadaptations in human chronic alcoholics: dysregulation of the NF-kappaB system. Plos One. 2: e930. PMID 17895971 DOI: 10.1371/Journal.Pone.0000930 |
0.322 |
|
| 2007 |
Liu J, Lewohl JM, Harris RA, Dodd PR, Mayfield RD. Altered gene expression profiles in the frontal cortex of cirrhotic alcoholics. Alcoholism, Clinical and Experimental Research. 31: 1460-6. PMID 17625000 DOI: 10.1111/J.1530-0277.2007.00444.X |
0.356 |
|
| 2007 |
Borghese CM, Harris RA. Studies of ethanol actions on recombinant delta-containing gamma-aminobutyric acid type A receptors yield contradictory results. Alcohol (Fayetteville, N.Y.). 41: 155-62. PMID 17521845 DOI: 10.1016/J.Alcohol.2007.03.006 |
0.538 |
|
| 2007 |
Sonner JM, Werner DF, Elsen FP, Xing Y, Liao M, Harris RA, Harrison NL, Fanselow MS, Eger EI, Homanics GE. Effect of isoflurane and other potent inhaled anesthetics on minimum alveolar concentration, learning, and the righting reflex in mice engineered to express alpha1 gamma-aminobutyric acid type A receptors unresponsive to isoflurane. Anesthesiology. 106: 107-13. PMID 17197852 DOI: 10.1097/00000542-200701000-00019 |
0.347 |
|
| 2007 |
Blednov YA, Cravatt BF, Boehm SL, Walker D, Harris RA. Role of endocannabinoids in alcohol consumption and intoxication: studies of mice lacking fatty acid amide hydrolase. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 1570-82. PMID 17164820 DOI: 10.1038/Sj.Npp.1301274 |
0.466 |
|
| 2006 |
Blednov YA, Walker D, Martinez M, Harris RA. Reduced alcohol consumption in mice lacking preprodynorphin. Alcohol (Fayetteville, N.Y.). 40: 73-86. PMID 17307643 DOI: 10.1016/J.Alcohol.2006.12.002 |
0.441 |
|
| 2006 |
Boehm SL, Ponomarev I, Blednov YA, Harris RA. From gene to behavior and back again: new perspectives on GABAA receptor subunit selectivity of alcohol actions. Advances in Pharmacology (San Diego, Calif.). 54: 171-203. PMID 17175815 DOI: 10.1016/S1054-3589(06)54008-6 |
0.524 |
|
| 2006 |
Crabbe JC, Phillips TJ, Harris RA, Arends MA, Koob GF. Alcohol-related genes: contributions from studies with genetically engineered mice. Addiction Biology. 11: 195-269. PMID 16961758 DOI: 10.1111/J.1369-1600.2006.00038.X |
0.388 |
|
| 2006 |
Krystal JH, Staley J, Mason G, Petrakis IL, Kaufman J, Harris RA, Gelernter J, Lappalainen J. Gamma-aminobutyric acid type A receptors and alcoholism: intoxication, dependence, vulnerability, and treatment. Archives of General Psychiatry. 63: 957-68. PMID 16952998 DOI: 10.1001/Archpsyc.63.9.957 |
0.409 |
|
| 2006 |
Werner DF, Blednov YA, Ariwodola OJ, Silberman Y, Logan E, Berry RB, Borghese CM, Matthews DB, Weiner JL, Harrison NL, Harris RA, Homanics GE. Knockin mice with ethanol-insensitive alpha1-containing gamma-aminobutyric acid type A receptors display selective alterations in behavioral responses to ethanol. The Journal of Pharmacology and Experimental Therapeutics. 319: 219-27. PMID 16785315 DOI: 10.1124/Jpet.106.106161 |
0.479 |
|
| 2006 |
Boehm SL, Homanics GE, Blednov YA, Harris RA. delta-Subunit containing GABAA receptor knockout mice are less sensitive to the actions of 4,5,6,7-tetrahydroisoxazolo-[5,4-c]pyridin-3-ol. European Journal of Pharmacology. 541: 158-62. PMID 16777089 DOI: 10.1016/J.Ejphar.2006.02.054 |
0.381 |
|
| 2006 |
Ponomarev I, Maiya R, Harnett MT, Schafer GL, Ryabinin AE, Blednov YA, Morikawa H, Boehm SL, Homanics GE, Berman AE, Berman A, Lodowski KH, Bergeson SE, Harris RA. Transcriptional signatures of cellular plasticity in mice lacking the alpha1 subunit of GABAA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5673-83. PMID 16723524 DOI: 10.1523/Jneurosci.0860-06.2006 |
0.35 |
|
| 2006 |
Won A, Oh I, Liao M, Sonner JM, Harris RA, Laster MJ, Brosnan R, Trudell JR, Eger EI. The minimum alveolar anesthetic concentration of 2-, 3-, and 4-alcohols and ketones in rats: relevance to anesthetic mechanisms. Anesthesia and Analgesia. 102: 1419-26. PMID 16632820 DOI: 10.1213/01.Ane.0000204258.00676.98 |
0.307 |
|
| 2006 |
Ogata J, Shiraishi M, Namba T, Smothers CT, Woodward JJ, Harris RA. Effects of anesthetics on mutant N-methyl-D-aspartate receptors expressed in Xenopus oocytes. The Journal of Pharmacology and Experimental Therapeutics. 318: 434-43. PMID 16622040 DOI: 10.1124/Jpet.106.101691 |
0.397 |
|
| 2006 |
Mulligan MK, Ponomarev I, Hitzemann RJ, Belknap JK, Tabakoff B, Harris RA, Crabbe JC, Blednov YA, Grahame NJ, Phillips TJ, Finn DA, Hoffman PL, Iyer VR, Koob GF, Bergeson SE. Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis. Proceedings of the National Academy of Sciences of the United States of America. 103: 6368-73. PMID 16618939 DOI: 10.1073/Pnas.0510188103 |
0.336 |
|
| 2006 |
Jung S, Harris RA. Sites in TM2 and 3 are critical for alcohol-induced conformational changes in GABA receptors. Journal of Neurochemistry. 96: 885-92. PMID 16405501 DOI: 10.1111/J.1471-4159.2005.03617.X |
0.446 |
|
| 2006 |
Liu J, Lewohl JM, Harris RA, Iyer VR, Dodd PR, Randall PK, Mayfield RD. Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 1574-82. PMID 16292326 DOI: 10.1038/Sj.Npp.1300947 |
0.328 |
|
| 2006 |
Borghese CM, Stórustovu SÃ, Ebert B, Herd MB, Belelli D, Lambert JJ, Marshall G, Wafford KA, Harris RA. The delta subunit of gamma-aminobutyric acid type A receptors does not confer sensitivity to low concentrations of ethanol. The Journal of Pharmacology and Experimental Therapeutics. 316: 1360-8. PMID 16272217 DOI: 10.1124/Jpet.105.092452 |
0.391 |
|
| 2006 |
Lobo IA, Trudell JR, Harris RA. Accessibility to residues in transmembrane segment four of the glycine receptor. Neuropharmacology. 50: 174-81. PMID 16225893 DOI: 10.1016/J.Neuropharm.2005.08.017 |
0.395 |
|
| 2006 |
Dodd PR, Tannenberg RK, Buckley ST, Eckert AL, Innes DJ, Mayfield RD, Harris RA. Interactions between serotonergic genotype and amino acid transmitter receptor expression in human alcoholics Alcoholism: Clinical and Experimental Research. 30. DOI: 10.1111/J.1530-0277.2006.00197.X |
0.415 |
|
| 2005 |
Blednov YA, Metten P, Finn DA, Rhodes JS, Bergeson SE, Harris RA, Crabbe JC. Hybrid C57BL/6J x FVB/NJ mice drink more alcohol than do C57BL/6J mice. Alcoholism, Clinical and Experimental Research. 29: 1949-58. PMID 16340451 DOI: 10.1097/01.Alc.0000187605.91468.17 |
0.364 |
|
| 2005 |
Hara K, Yamakura T, Sata T, Harris RA. The effects of anesthetics and ethanol on α2 adrenoceptor subtypes expressed with G protein-coupled inwardly rectifying potassium channels in Xenopus oocytes Anesthesia & Analgesia. 101: 1381-1388. PMID 16243998 DOI: 10.1213/01.Ane.0000180190.05238.D5 |
0.316 |
|
| 2005 |
Lobo IA, Harris RA. Sites of alcohol and volatile anesthetic action on glycine receptors. International Review of Neurobiology. 65: 53-87. PMID 16140053 DOI: 10.1016/S0074-7742(04)65003-3 |
0.391 |
|
| 2005 |
Blednov YA, Bergeson SE, Walker D, Ferreira VM, Kuziel WA, Harris RA. Perturbation of chemokine networks by gene deletion alters the reinforcing actions of ethanol. Behavioural Brain Research. 165: 110-25. PMID 16105698 DOI: 10.1016/J.Bbr.2005.06.026 |
0.409 |
|
| 2005 |
Liao M, Sonner JM, Jurd R, Rudolph U, Borghese CM, Harris RA, Laster MJ, Eger EI. Beta3-containing gamma-aminobutyric acidA receptors are not major targets for the amnesic and immobilizing actions of isoflurane. Anesthesia and Analgesia. 101: 412-8, table of cont. PMID 16037154 DOI: 10.1213/01.Ane.0000154196.86587.35 |
0.415 |
|
| 2005 |
Jung S, Akabas MH, Harris RA. Functional and structural analysis of the GABAA receptor alpha 1 subunit during channel gating and alcohol modulation. The Journal of Biological Chemistry. 280: 308-16. PMID 15522868 DOI: 10.1074/Jbc.M409871200 |
0.434 |
|
| 2004 |
Blednov YA, Walker D, Osterndorf-Kahanek E, Harris RA. Mice lacking metabotropic glutamate receptor 4 do not show the motor stimulatory effect of ethanol. Alcohol (Fayetteville, N.Y.). 34: 251-9. PMID 15902920 DOI: 10.1016/J.Alcohol.2004.10.003 |
0.417 |
|
| 2004 |
Blednov YA, Walker D, Harris RA. Blockade of the leptin-sensitive pathway markedly reduces alcohol consumption in mice. Alcoholism, Clinical and Experimental Research. 28: 1683-92. PMID 15547455 DOI: 10.1097/01.Alc.0000145790.60216.C8 |
0.419 |
|
| 2004 |
Lewohl JM, Van Dyk DD, Craft GE, Innes DJ, Mayfield RD, Cobon G, Harris RA, Dodd PR. The application of proteomics to the human alcoholic brain. Annals of the New York Academy of Sciences. 1025: 14-26. PMID 15542695 DOI: 10.1196/Annals.1316.002 |
0.355 |
|
| 2004 |
Boehm SL, Peden L, Jennings AW, Kojima N, Harris RA, Blednov YA. Over-expression of the fyn-kinase gene reduces hypnotic sensitivity to ethanol in mice. Neuroscience Letters. 372: 6-11. PMID 15531078 DOI: 10.1016/J.Neulet.2004.08.028 |
0.435 |
|
| 2004 |
Boehm SL, Ponomarev I, Jennings AW, Whiting PJ, Rosahl TW, Garrett EM, Blednov YA, Harris RA. gamma-Aminobutyric acid A receptor subunit mutant mice: new perspectives on alcohol actions. Biochemical Pharmacology. 68: 1581-602. PMID 15451402 DOI: 10.1016/J.Bcp.2004.07.023 |
0.529 |
|
| 2004 |
Liu J, Lewohl JM, Dodd PR, Randall PK, Harris RA, Mayfield RD. Gene expression profiling of individual cases reveals consistent transcriptional changes in alcoholic human brain. Journal of Neurochemistry. 90: 1050-8. PMID 15312160 DOI: 10.1111/J.1471-4159.2004.02570.X |
0.319 |
|
| 2004 |
Lobo IA, Trudell JR, Harris RA. Cross-linking of glycine receptor transmembrane segments two and three alters coupling of ligand binding with channel opening. Journal of Neurochemistry. 90: 962-9. PMID 15287902 DOI: 10.1111/J.1471-4159.2004.02561.X |
0.363 |
|
| 2004 |
Zhang Y, Sonner JM, Eger EI, Stabernack CR, Laster MJ, Raines DE, Harris RA. Gamma-aminobutyric acidA receptors do not mediate the immobility produced by isoflurane. Anesthesia and Analgesia. 99: 85-90. PMID 15281509 DOI: 10.1213/01.Ane.0000118108.64886.42 |
0.36 |
|
| 2004 |
Lobo IA, Mascia MP, Trudell JR, Harris RA. Channel gating of the glycine receptor changes accessibility to residues implicated in receptor potentiation by alcohols and anesthetics. The Journal of Biological Chemistry. 279: 33919-27. PMID 15169788 DOI: 10.1074/Jbc.M313941200 |
0.382 |
|
| 2004 |
Shiraishi M, Harris RA. Effects of Alcohols and Anesthetics on Recombinant Voltage-Gated Na+ Channels Journal of Pharmacology and Experimental Therapeutics. 309: 987-994. PMID 14978193 DOI: 10.1124/Jpet.103.064063 |
0.348 |
|
| 2004 |
Boehm SL, Peden L, Harris RA, Blednov YA. Deletion of the fyn-kinase gene alters sensitivity to GABAergic drugs: dependence on beta2/beta3 GABAA receptor subunits. The Journal of Pharmacology and Experimental Therapeutics. 309: 1154-9. PMID 14764659 DOI: 10.1124/Jpet.103.064444 |
0.379 |
|
| 2003 |
Borghese CM, Henderson LA, Bleck V, Trudell JR, Harris RA. Sites of excitatory and inhibitory actions of alcohols on neuronal alpha2beta4 nicotinic acetylcholine receptors. The Journal of Pharmacology and Experimental Therapeutics. 307: 42-52. PMID 14500778 DOI: 10.1124/Jpet.102.053710 |
0.43 |
|
| 2003 |
Borghese CM, Wang L, Bleck V, Harris RA. Mutation in neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes blocks ethanol action. Addiction Biology. 8: 313-8. PMID 13129833 DOI: 10.1080/13556210310001602220 |
0.41 |
|
| 2003 |
Findlay GS, Phelan R, Roberts MT, Homanics GE, Bergeson SE, Lopreato GF, Mihic SJ, Blednov YA, Harris RA. Glycine receptor knock-in mice and hyperekplexia-like phenotypes: comparisons with the null mutant. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 8051-9. PMID 12954867 DOI: 10.1523/Jneurosci.23-22-08051.2003 |
0.371 |
|
| 2003 |
Boehm SL, Peden L, Chang R, Harris RA, Blednov YA. Deletion of the fyn-kinase gene alters behavioral sensitivity to ethanol. Alcoholism, Clinical and Experimental Research. 27: 1033-40. PMID 12878908 DOI: 10.1097/01.Alc.0000075822.80583.71 |
0.447 |
|
| 2003 |
Zhang Y, Laster MJ, Hara K, Harris RA, Eger EI, Stabernack CR, Sonner JM. Glycine receptors mediate part of the immobility produced by inhaled anesthetics. Anesthesia and Analgesia. 96: 97-101, table of con. PMID 12505932 DOI: 10.1097/00000539-200301000-00021 |
0.355 |
|
| 2003 |
Blednov YA, Jung S, Alva H, Wallace D, Rosahl T, Whiting PJ, Harris RA. Deletion of the alpha1 or beta2 subunit of GABAA receptors reduces actions of alcohol and other drugs. The Journal of Pharmacology and Experimental Therapeutics. 304: 30-6. PMID 12490572 DOI: 10.1124/Jpet.102.042960 |
0.371 |
|
| 2002 |
Hara K, Eger EI, Laster MJ, Harris RA. Nonhalogenated alkanes cyclopropane and butane affect neurotransmitter-gated ion channel and G-protein-coupled receptors: differential actions on GABAA and glycine receptors. Anesthesiology. 97: 1512-20. PMID 12459679 DOI: 10.1097/00000542-200212000-00025 |
0.35 |
|
| 2002 |
Harris RA, Morrisett RA. Two-shot cocktail: adenosine, dopamine and a twist of beta gamma. Nature Medicine. 8: 777-9. PMID 12152026 DOI: 10.1038/Nm0802-777 |
0.375 |
|
| 2002 |
Maiya R, Buck KJ, Harris RA, Mayfield RD. Ethanol-sensitive sites on the human dopamine transporter. The Journal of Biological Chemistry. 277: 30724-9. PMID 12070173 DOI: 10.1074/Jbc.M204914200 |
0.427 |
|
| 2002 |
Mayfield RD, Lewohl JM, Dodd PR, Herlihy A, Liu J, Harris RA. Patterns of gene expression are altered in the frontal and motor cortices of human alcoholics. Journal of Neurochemistry. 81: 802-13. PMID 12065639 DOI: 10.1046/J.1471-4159.2002.00860.X |
0.324 |
|
| 2002 |
Findlay GS, Wick MJ, Mascia MP, Wallace D, Miller GW, Harris RA, Blednov YA. Transgenic expression of a mutant glycine receptor decreases alcohol sensitivity of mice. The Journal of Pharmacology and Experimental Therapeutics. 300: 526-34. PMID 11805213 DOI: 10.1124/Jpet.300.2.526 |
0.344 |
|
| 2002 |
Borghese CM, Harris RA. Anesthetic-induced immobility: neuronal nicotinic acetylcholine receptors are no longer in the picture. Anesthesia & Analgesia. 95: 509-511. DOI: 10.1213/00000539-200209000-00001 |
0.368 |
|
| 2002 |
Borghese CM, Ali DN, Bleck V, Harris RA. Acetylcholine and alcohol sensitivity of neuronal nicotinic acetylcholine receptors: mutations in transmembrane domains. Alcoholism: Clinical and Experimental Research. 26: 1764-1772. DOI: 10.1111/J.1530-0277.2002.Tb02482.X |
0.436 |
|
| 2001 |
Hara K, Lewohl JM, Yamakura T, Harris RA. Mutational analysis of ethanol interactions with G-protein-coupled inwardly rectifying potassium channels. Alcohol. 24: 5-8. PMID 11524176 DOI: 10.1016/S0741-8329(01)00134-3 |
0.36 |
|
| 2001 |
Yamakura T, Lewohl JM, Harris RA. Differential effects of general anesthetics on G protein-coupled inwardly rectifying and other potassium channels. Anesthesiology. 95: 144-153. PMID 11465552 DOI: 10.1097/00000542-200107000-00025 |
0.335 |
|
| 2001 |
Findlay GS, Ueno S, Harrison NL, Harris RA. Allosteric modulation in spontaneously active mutant gamma-aminobutyric acidA receptors. Neuroscience Letters. 305: 77-80. PMID 11356312 DOI: 10.1016/S0304-3940(01)01646-9 |
0.437 |
|
| 2001 |
Godden EL, Harris RA, Dunwiddie TV. Correlation between molecular volume and effects of n-alcohols on human neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes. The Journal of Pharmacology and Experimental Therapeutics. 296: 716-22. PMID 11181898 |
0.631 |
|
| 2001 |
Lewohl JM, Dodd PR, Mayfield RD, Harris RA. Application of DNA microarrays to study human alcoholism. Journal of Biomedical Science. 8: 28-36. PMID 11173973 DOI: 10.1007/Bf02255968 |
0.329 |
|
| 2000 |
Findlay GS, Ueno S, Harrison NL, Harris RA. Allosteric modulation in spontaneously active mutant gamma-aminobutyric acid(A) receptors [corrected]. Neuroscience Letters. 293: 155-8. PMID 11036184 DOI: 10.1016/S0304-3940(00)01503-2 |
0.389 |
|
| 2000 |
Yamakura T, Harris RA. Effects of gaseous anesthetics nitrous oxide and xenon on ligand-gated ion channels: Comparison with isoflurane and ethanol Anesthesiology. 93: 1095-1101. PMID 11020766 DOI: 10.1097/00000542-200010000-00034 |
0.346 |
|
| 2000 |
Yamakura T, Borghese C, Harris RA. A transmembrane site determines sensitivity of neuronal nicotinic acetylcholine receptors to general anesthetics. Journal of Biological Chemistry. 275: 40879-40886. PMID 11020384 DOI: 10.1074/Jbc.M005771200 |
0.374 |
|
| 2000 |
Ueno S, Lin A, Nikolaeva N, Trudell JR, Mihic SJ, Harris RA, Harrison NL. Tryptophan scanning mutagenesis in TM2 of the GABA(A) receptor alpha subunit: effects on channel gating and regulation by ethanol. British Journal of Pharmacology. 131: 296-302. PMID 10991923 DOI: 10.1038/Sj.Bjp.0703504 |
0.427 |
|
| 2000 |
Baer K, Essrich C, Balsiger S, Wick MJ, Harris RA, Fritschy JM, Lüscher B. Rescue of γ2 subunit-deficient mice by transgenic overexpression of the GABA(A) receptor γ2S or γ2L subunit isoforms European Journal of Neuroscience. 12: 2639-2643. PMID 10947838 DOI: 10.1046/J.1460-9568.2000.00159.X |
0.412 |
|
| 2000 |
Wick MJ, Radcliffe RA, Bowers BJ, Mascia MP, Lüscher B, Harris RA, Wehner JM. Behavioural changes produced by transgenic overexpression of gamma2L and gamma2S subunits of the GABAA receptor. The European Journal of Neuroscience. 12: 2634-8. PMID 10947837 DOI: 10.1046/J.1460-9568.2000.00160.X |
0.46 |
|
| 2000 |
Mascia MP, Trudell JR, Harris RA. Specific binding sites for alcohols and anesthetics on ligand-gated ion channels. Proceedings of the National Academy of Sciences of the United States of America. 97: 9305-10. PMID 10908659 DOI: 10.1073/Pnas.160128797 |
0.41 |
|
| 2000 |
Yamakura T, Chavez-Noriega LE, Harris RA. Subunit-dependent inhibition of human neuronal nicotinic acetylcholine receptors and other ligand-gated ion channels by dissociative anesthetics ketamine and dizocilpine. Anesthesiology. 92: 1144-1153. PMID 10754635 DOI: 10.1097/00000542-200004000-00033 |
0.419 |
|
| 2000 |
Mascia MP, Gong DH, Eger EI, Harris RA. The Anesthetic Potency of Propanol and Butanol Versus Propanethiol and Butanethiol in α1 Wild Type and α1(s267q) Glycine Receptors Anesthesia & Analgesia. 91: 1289-1293. DOI: 10.1213/00000539-200011000-00044 |
0.423 |
|
| 2000 |
Lewohl JM, Wang L, Miles MF, Zhang L, Dodd PR, Harris RA. Gene Expression in Human Alcoholism: Microarray Analysis of Frontal Cortex Alcoholism: Clinical and Experimental Research. 24: 1873-1882. DOI: 10.1111/J.1530-0277.2000.Tb01993.X |
0.356 |
|
| 1999 |
Lewohl JM, Wilson WR, Mayfield RD, Brozowski SJ, Morrisett RA, Harris RA. G-protein-coupled inwardly rectifying potassium channels are targets of alcohol action. Nature Neuroscience. 2: 1084-90. PMID 10570485 DOI: 10.1038/16012 |
0.43 |
|
| 1999 |
Yamakura T, Mihic SJ, Harris RA. Amino acid volume and hydropathy of a transmembrane site determine glycine and anesthetic sensitivity of glycine receptors. The Journal of Biological Chemistry. 274: 23006-12. PMID 10438467 DOI: 10.1074/Jbc.274.33.23006 |
0.337 |
|
| 1999 |
Ueno S, Wick MJ, Ye Q, Harrison NL, Harris RA. Subunit mutations affect ethanol actions on GABA(A) receptors expressed in Xenopus oocytes. British Journal of Pharmacology. 127: 377-82. PMID 10385236 DOI: 10.1038/Sj.Bjp.0702563 |
0.425 |
|
| 1999 |
Cardoso RA, Brozowski SJ, Chavez-Noriega LE, Harpold M, Valenzuela CF, Harris RA. Effects of ethanol on recombinant human neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes. The Journal of Pharmacology and Experimental Therapeutics. 289: 774-80. PMID 10215652 |
0.599 |
|
| 1999 |
Ueno S, Trudell JR, Eger EI, Harris RA. Actions of fluorinated alkanols on GABA(A) receptors: relevance to theories of narcosis. Anesthesia and Analgesia. 88: 877-83. PMID 10195541 DOI: 10.1097/00000539-199904000-00036 |
0.331 |
|
| 1999 |
Ueno S, Trudell JR, Eger EI, Harris RA. Actions of Fluorinated Alkanols on GABAA Receptors Anesthesia & Analgesia. 88: 877-883. DOI: 10.1213/00000539-199904000-00036 |
0.337 |
|
| 1999 |
Harris RA. Ethanol Actions on Multiple Ion Channels: Which Are Important? Alcoholism: Clinical and Experimental Research. 23: 1563-1570. DOI: 10.1111/J.1530-0277.1999.Tb04045.X |
0.401 |
|
| 1998 |
Chandler LJ, Harris RA, Crews FT. Ethanol tolerance and synaptic plasticity. Trends in Pharmacological Sciences. 19: 491-5. PMID 9871410 DOI: 10.1016/S0165-6147(98)01268-1 |
0.463 |
|
| 1998 |
Mascia MP, Wick MJ, Martinez LD, Harris RA. Enhancement of glycine receptor function by ethanol: role of phosphorylation. British Journal of Pharmacology. 125: 263-70. PMID 9786497 DOI: 10.1038/Sj.Bjp.0702054 |
0.429 |
|
| 1998 |
Valenzuela CF, Bhave S, Hoffman P, Harris RA. Acute effects of ethanol on pharmacologically isolated kainate receptors in cerebellar granule neurons: comparison with NMDA and AMPA receptors. Journal of Neurochemistry. 71: 1777-80. PMID 9751216 DOI: 10.1046/J.1471-4159.1998.71041777.X |
0.591 |
|
| 1998 |
Valenzuela CF, Cardoso RA, Wick MJ, Weiner JL, Dunwiddie TV, Harris RA. Effects of ethanol on recombinant glycine receptors expressed in mammalian cell lines. Alcoholism, Clinical and Experimental Research. 22: 1132-6. PMID 9726286 DOI: 10.1111/J.1530-0277.1998.Tb03712.X |
0.706 |
|
| 1998 |
Harris RA, Mihic SJ, Valenzuela CF. Alcohol and benzodiazepines: recent mechanistic studies. Drug and Alcohol Dependence. 51: 155-64. PMID 9716937 DOI: 10.1016/S0376-8716(98)00073-8 |
0.447 |
|
| 1998 |
Wick MJ, Mihic SJ, Ueno S, Mascia MP, Trudell JR, Brozowski SJ, Ye Q, Harrison NL, Harris RA. Mutations of gamma-aminobutyric acid and glycine receptors change alcohol cutoff: evidence for an alcohol receptor? Proceedings of the National Academy of Sciences of the United States of America. 95: 6504-9. PMID 9600996 DOI: 10.1073/Pnas.95.11.6504 |
0.412 |
|
| 1998 |
Ye Q, Koltchine VV, Mihic SJ, Mascia MP, Wick MJ, Finn SE, Harrison NL, Harris RA. Enhancement of glycine receptor function by ethanol is inversely correlated with molecular volume at position alpha267. The Journal of Biological Chemistry. 273: 3314-9. PMID 9452448 DOI: 10.1074/Jbc.273.6.3314 |
0.51 |
|
| 1998 |
Minami K, Gereau RW, Minami M, Heinemann SF, Harris RA. Effects of ethanol and anesthetics on type 1 and 5 metabotropic glutamate receptors expressed in Xenopus laevis oocytes. Molecular Pharmacology. 53: 148-56. PMID 9443943 DOI: 10.1124/Mol.53.1.148 |
0.408 |
|
| 1998 |
Harris RA, Valenzuela CF, Brozowski S, Chuang L, Hadingham K, Whiting PJ. Adaptation of gamma-aminobutyric acid type A receptors to alcohol exposure: studies with stably transfected cells. The Journal of Pharmacology and Experimental Therapeutics. 284: 180-8. PMID 9435176 |
0.584 |
|
| 1998 |
Weiner JL, Buhler AV, Whatley VJ, Harris RA, Dunwiddie TV. Colchicine is a competitive antagonist at human recombinant gamma-aminobutyric acidA receptors. The Journal of Pharmacology and Experimental Therapeutics. 284: 95-102. PMID 9435166 |
0.6 |
|
| 1997 |
Minami K, Vanderah TW, Minami M, Harris RA. Inhibitory effects of anesthetics and ethanol on muscarinic receptors expressed in Xenopus oocytes. European Journal of Pharmacology. 339: 237-44. PMID 9473141 DOI: 10.1016/S0014-2999(97)01354-X |
0.386 |
|
| 1997 |
Mihic SJ, Ye Q, Wick MJ, Koltchine VV, Krasowski MD, Finn SE, Mascia MP, Valenzuela CF, Hanson KK, Greenblatt EP, Harris RA, Harrison NL. Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors. Nature. 389: 385-9. PMID 9311780 DOI: 10.1038/38738 |
0.584 |
|
| 1996 |
Harris RA. Transfected cells for study of alcohol actions on GABAA receptors Addiction Biology. 1: 157-163. PMID 12893475 DOI: 10.1080/1355621961000124776 |
0.434 |
|
| 1996 |
Huidobro-Toro JP, Valenzuela CF, Harris RA. Modulation of GABAA receptor function by G protein-coupled 5-HT2C receptors. Neuropharmacology. 35: 1355-63. PMID 9014152 DOI: 10.1016/S0028-3908(96)00084-6 |
0.502 |
|
| 1996 |
Mascia MP, Machu TK, Harris RA. Enhancement of homomeric glycine receptor function by long-chain alcohols and anaesthetics. British Journal of Pharmacology. 119: 1331-6. PMID 8968539 DOI: 10.1111/j.1476-5381.1996.tb16042.x |
0.301 |
|
| 1996 |
Blednov YA, Bleck V, Harris RA. Measurement of glycine receptor function by radioactive chloride uptake Journal of Neuroscience Methods. 68: 253-257. PMID 8912198 DOI: 10.1016/0165-0270(96)00088-X |
0.369 |
|
| 1996 |
Whatley VJ, Brozowski SJ, Hadingham KL, Whiting PJ, Harris RA. Microtubule depolymerization inhibits ethanol-induced enhancement of GABAA responses in stably transfected cells Journal of Neurochemistry. 66: 1318-1321. PMID 8769900 |
0.305 |
|
| 1996 |
Mascia MP, Mihic SJ, Valenzuela CF, Schofield PR, Harris RA. A single amino acid determines differences in ethanol actions on strychnine-sensitive glycine receptors. Molecular Pharmacology. 50: 402-6. PMID 8700149 |
0.526 |
|
| 1996 |
Valenzuela CF, Xiong Z, MacDonald JF, Weiner JL, Frazier CJ, Dunwiddie TV, Kazlauskas A, Whiting PJ, Harris RA. Platelet-derived growth factor induces a long-term inhibition of N-methyl-D-aspartate receptor function. The Journal of Biological Chemistry. 271: 16151-9. PMID 8663218 DOI: 10.1074/Jbc.271.27.16151 |
0.608 |
|
| 1995 |
Valenzuela CF, Kazlauskas A, Brozowski SJ, Weiner JL, Demali KA, McDonald BJ, Moss SJ, Dunwiddie TV, Harris RA. Platelet-derived growth factor receptor is a novel modulator of type A gamma-aminobutyric acid-gated ion channels. Molecular Pharmacology. 48: 1099-107. PMID 8848010 |
0.639 |
|
| 1995 |
Klein RL, Mascia MP, Whiting PJ, Harris RA. GABAA receptor function and binding in stably transfected cells: chronic ethanol treatment. Alcoholism, Clinical and Experimental Research. 19: 1338-44. PMID 8561312 DOI: 10.1111/J.1530-0277.1995.Tb01622.X |
0.368 |
|
| 1995 |
Harris RA, Proctor WR, McQuilkin SJ, Klein RL, Mascia MP, Whatley V, Whiting PJ, Dunwiddie TV. Ethanol increases GABAA responses in cells stably transfected with receptor subunits. Alcoholism, Clinical and Experimental Research. 19: 226-32. PMID 7771653 DOI: 10.1111/J.1530-0277.1995.Tb01496.X |
0.691 |
|
| 1995 |
Harris RA, McQuilkin SJ, Paylor R, Abeliovich A, Tonegawa S, Wehner JM. Mutant mice lacking the gamma isoform of protein kinase C show decreased behavioral actions of ethanol and altered function of gamma-aminobutyrate type A receptors. Proceedings of the National Academy of Sciences of the United States of America. 92: 3658-62. PMID 7731960 DOI: 10.1073/Pnas.92.9.3658 |
0.338 |
|
| 1995 |
Valenzuela CF, Machu TK, McKernan RM, Whiting P, VanRenterghem BB, McManaman JL, Brozowski SJ, Smith GB, Olsen RW, Harris RA. Tyrosine kinase phosphorylation of GABAA receptors. Brain Research. Molecular Brain Research. 31: 165-72. PMID 7476025 DOI: 10.1016/0169-328X(95)00048-W |
0.457 |
|
| 1994 |
Avdulov NA, Wood WG, Harris RA. Effects of ethanol on structural parameters of rat brain membranes: relationship to genetic differences in ethanol sensitivity. Alcoholism: Clinical and Experimental Research. 18: 53-59. PMID 8198227 DOI: 10.1111/J.1530-0277.1994.Tb00880.X |
0.379 |
|
| 1994 |
Mihic SJ, Whiting PJ, Harris RA. Anaesthetic concentrations of alcohols potentiate GABAA receptor-mediated currents: lack of subunit specificity. European Journal of Pharmacology. 268: 209-14. PMID 7957642 DOI: 10.1016/0922-4106(94)90190-2 |
0.301 |
|
| 1993 |
Wafford KA, Burnett D, Harris RA, Whiting PJ. GABAA receptor subunit expression and sensitivity to ethanol. Alcohol and Alcoholism (Oxford, Oxfordshire). Supplement. 2: 327-30. PMID 7748319 |
0.332 |
|
| 1993 |
Lin L‐, Whiting P, Harris RA. Molecular determinants of general anesthetic action: role of GABAA receptor structure. Journal of Neurochemistry. 60: 1548-1553. PMID 7681105 DOI: 10.1111/J.1471-4159.1993.Tb03320.X |
0.455 |
|
| 1992 |
Harris RA, Brodie MS, Dunwiddie TV. Possible substrates of ethanol reinforcement: GABA and dopamine. Annals of the New York Academy of Sciences. 654: 61-9. PMID 1321582 DOI: 10.1111/J.1749-6632.1992.Tb25956.X |
0.611 |
|
| 1992 |
Samson HH, Harris RA. Neurobiology of alcohol abuse. Trends in Pharmacological Sciences. 13: 206-11. PMID 1306042 DOI: 10.1016/0165-6147(92)90065-E |
0.43 |
|
| 1991 |
Harris RA. Mammalian Genetics in the Study of Alcohol and Anesthetic Actions Annals of the New York Academy of Sciences. 625: 508-514. PMID 2058902 DOI: 10.1111/J.1749-6632.1991.Tb33881.X |
0.375 |
|
| 1991 |
Daniell LC, Harris RA. Effect of Chronic Ethanol Treatment and Selective Breeding for Sensitivity to Ethanol on Calcium Release Induced by Inositol Trisphosphate for Ethanol from Brain and Liver Microsomes Alcoholism: Clinical and Experimental Research. 15: 224-228. PMID 2058799 DOI: 10.1111/J.1530-0277.1991.Tb01860.X |
0.352 |
|
| 1991 |
Buck KJ, Harris RA. Neuroadaptive responses to chronic ethanol. Alcoholism, Clinical and Experimental Research. 15: 460-70. PMID 1715134 DOI: 10.1111/J.1530-0277.1991.Tb00544.X |
0.419 |
|
| 1991 |
Wafford KA, Burnett DM, Leidenheimer NJ, Burt DR, Wang JB, Kofuji P, Dunwiddie TV, Harris RA, Sikela JM. Ethanol sensitivity of the GABAA receptor expressed in Xenopus oocytes requires 8 amino acids contained in the gamma 2L subunit. Neuron. 7: 27-33. PMID 1712603 DOI: 10.1016/0896-6273(91)90071-7 |
0.639 |
|
| 1991 |
Buck KJ, McQuilkin SJ, Harris RA. Modulation of gamma-aminobutyric acidA receptor-operated chloride channels by benzodiazepine inverse agonists is related to genetic differences in ethanol withdrawal seizure severity. Journal of Neurochemistry. 57: 2100-5. PMID 1658234 DOI: 10.1111/J.1471-4159.1991.Tb06428.X |
0.432 |
|
| 1991 |
Buck KJ, Hahner L, Sikela J, Harris RA. Chronic ethanol treatment alters brain levels of gamma-aminobutyric acidA receptor subunit mRNAs: relationship to genetic differences in ethanol withdrawal seizure severity. Journal of Neurochemistry. 57: 1452-5. PMID 1654394 DOI: 10.1111/J.1471-4159.1991.Tb08313.X |
0.454 |
|
| 1991 |
Allan AM, Burnett D, Harris RA. Ethanol-induced changes in chloride flux are mediated by both GABA(A) and GABA(B) receptors Alcoholism: Clinical and Experimental Research. 15: 233-237. PMID 1647705 DOI: 10.1111/J.1530-0277.1991.Tb01862.X |
0.423 |
|
| 1991 |
Buck KJ, Heim H, Harris RA. Reversal of alcohol dependence and tolerance by a single administration of flumazenil. The Journal of Pharmacology and Experimental Therapeutics. 257: 984-9. PMID 1646333 |
0.33 |
|
| 1990 |
Leidenheimer NJ, Browning MD, Dunwiddie TV, Hahner LD, Harris RA. Phosphorylation-independent effects of second messenger system modulators on gamma-aminobutyric acidA receptor complex function. Molecular Pharmacology. 38: 823-8. PMID 2174503 |
0.566 |
|
| 1990 |
Buck KJ, Harris RA. Benzodiazepine agonist and inverse agonist actions on GABAA receptor-operated chloride channels. II. Chronic effects of ethanol. The Journal of Pharmacology and Experimental Therapeutics. 253: 713-9. PMID 2160008 |
0.33 |
|
| 1990 |
Buck KJ, Harris RA. Benzodiazepine agonist and inverse agonist actions on GABAA receptor-operated chloride channels. I. Acute effects of ethanol. The Journal of Pharmacology and Experimental Therapeutics. 253: 706-12. PMID 2160007 |
0.328 |
|
| 1990 |
Wafford KA, Burnett DM, Dunwiddie TV, Harris RA. Genetic differences in the ethanol sensitivity of GABAA receptors expressed in Xenopus oocytes. Science (New York, N.Y.). 249: 291-3. PMID 1695761 |
0.629 |
|
| 1990 |
Harris RA. Distinct actions of alcohols, barbiturates and benzodiazepines on GABA-activated chloride channels Alcohol. 7: 273-275. PMID 1691915 DOI: 10.1016/0741-8329(90)90017-7 |
0.397 |
|
| 1990 |
McQuilkin SJ, Harris RA. Factors affecting actions of ethanol on GABA-activated chloride channels Life Sciences. 46: 527-541. PMID 1689450 DOI: 10.1016/0024-3205(90)90009-G |
0.454 |
|
| 1989 |
Buck KJ, Allan AM, Harris RA. Fluidization of brain membranes by A2C does not produce anesthesia and does not augment muscimol-stimulated 36Cl- influx. European Journal of Pharmacology. 160: 359-67. PMID 2714367 DOI: 10.1016/0014-2999(89)90091-5 |
0.377 |
|
| 1989 |
Deitrich RA, Dunwiddie TV, Harris RA, Erwin VG. Mechanism of action of ethanol: initial central nervous system actions. Pharmacological Reviews. 41: 489-537. PMID 2700603 |
0.584 |
|
| 1989 |
Wafford KA, Dunwiddie TV, Harris RA. Calcium-dependent chloride currents elicited by injection of ethanol into Xenopus oocytes. Brain Research. 505: 215-9. PMID 2557132 DOI: 10.1016/0006-8993(89)91445-5 |
0.577 |
|
| 1989 |
Lewin E, Peris J, Bleck V, Zahniser NR, Harris RA. Diazepam sensitizes mice to FG 7142 and reduces muscimol-stimulated 36Cl- flux. Pharmacology, Biochemistry, and Behavior. 33: 465-8. PMID 2479037 DOI: 10.1016/0091-3057(89)90531-5 |
0.334 |
|
| 1988 |
Feller DJ, Harris RA, Crabbe JC. Differences in GABA activity between ethanol withdrawal seizure prone and resistant mice. European Journal of Pharmacology. 157: 147-54. PMID 3224635 DOI: 10.1016/0014-2999(88)90377-9 |
0.383 |
|
| 1988 |
Harris RA, Allan AM, Daniell LC, Nixon C. Antagonism of ethanol and pentobarbital actions by benzodiazepine inverse agonists: Neurochemical studies Journal of Pharmacology and Experimental Therapeutics. 247: 1012-1017. PMID 2849653 |
0.311 |
|
| 1988 |
Allan AM, Gallaher EJ, Gionet SE, Harris RA. Genetic selection for benzodiazepine ataxia produces functional changes in the γ-aminobutyric acid receptor chloride channel complex Brain Research. 452: 118-126. PMID 2456824 DOI: 10.1016/0006-8993(88)90016-9 |
0.394 |
|
| 1988 |
Daniell LC, Harris RA. Effect of chronic ethanol treatment and selective breeding for hypnotic sensitivity to ethanol on intracellular ionized calcium concentrations in synaptosomes. Alcoholism: Clinical and Experimental Research. 12: 179-183. PMID 2450482 DOI: 10.1111/J.1530-0277.1988.Tb00156.X |
0.432 |
|
| 1987 |
Harris RA, Burnett R, Mcquilkin S, Mcclard A, Simon FR. Effects of ethanol on membrane order: fluorescence studies. Annals of the New York Academy of Sciences. 492: 125-135. PMID 3474923 DOI: 10.1111/J.1749-6632.1987.Tb48660.X |
0.324 |
|
| 1987 |
Allan AM, Harris RA. Acute and chronic ethanol treatments alter GABA receptor-operated chloride channels Pharmacology, Biochemistry and Behavior. 27: 665-670. PMID 2443933 DOI: 10.1016/0091-3057(87)90192-4 |
0.303 |
|
| 1987 |
Allan AM, Harris RA. Involvement of neuronal chloride channels in ethanol intoxication, tolerance, and dependence Recent Developments in Alcoholism : An Official Publication of the American Medical Society On Alcoholism, the Research Society On Alcoholism, and the National Council On Alcoholism. 5: 313-325. PMID 2436258 DOI: 10.1007/978-1-4899-1684-6_12 |
0.305 |
|
| 1986 |
Allan AM, Harris RA. Gamma-aminobutyric acid and alcohol actions: Neurochemical studies of long sleep and short sleep mice Life Sciences. 39: 2005-2015. PMID 3784767 DOI: 10.1016/0024-3205(86)90324-3 |
0.414 |
|
| 1985 |
Mitchell MA, Peris J, Harris RA. Barbiturate tolerance and dependence: effects on synaptosomal sodium transport and membrane fluidity. Pharmacology, Biochemistry, and Behavior. 22: 955-60. PMID 4040639 DOI: 10.1016/0091-3057(85)90302-8 |
0.329 |
|
| 1984 |
Harris RA, Crabbe JC, McSwigan JD. Relationship of membrane physical properties to alcohol dependence in mice selected for genetic differences in alcohol withdrawal. Life Sciences. 35: 2601-8. PMID 6542619 DOI: 10.1016/0024-3205(84)90027-4 |
0.392 |
|
| 1983 |
Yamamoto HA, Harris RA. Calcium-dependent 86Rb efflux and ethanol intoxication: Studies of human red blood cells and rodent brain synaptosomes European Journal of Pharmacology. 88: 357-363. PMID 6861876 DOI: 10.1016/0014-2999(83)90586-1 |
0.332 |
|
| 1983 |
Harris RA, Fenner D, Feller D, Sieckman G, Lloyd S, Mitchell M, Dexter JD, Tumbelson ME, Bylund DB. Neurochemical effects of long-term ingestion of ethanol by Sinclair (S-1) swine. Pharmacology, Biochemistry, and Behavior. 18: 363-7. PMID 6132410 DOI: 10.1016/0091-3057(83)90455-0 |
0.31 |
|
| 1982 |
Harris RA, Fenner D. [Ethanol and synaptosomal calcium binding]. Biochemical Pharmacology. 31: 1790-2. PMID 7104042 DOI: 10.1016/0006-2952(82)90688-8 |
0.358 |
|
| 1982 |
Rohde BH, Harris RA. GABA and flunitrazepam binding to neuroblastoma cell membranes--effects of growth conditions, ethanol and pentobarbital. Brain Research. 253: 133-141. PMID 6129916 DOI: 10.1016/0006-8993(82)90680-1 |
0.357 |
|
| 1980 |
Snell D, Harris RA. Impairment of avoidance behavior following short-term ingestion of ethanol, tertiary-butanol, or pentobarbital in mice. Psychopharmacology. 69: 53-57. PMID 6771827 DOI: 10.1007/Bf00426521 |
0.357 |
|
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