Mainak Guharoy - Publications

Affiliations: 
VIB-VUB Center for Structural Biology VIB-VUB Brussels Belgium 

32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Guharoy M, Lazar T, Macossay-Castillo M, Tompa P. Degron masking outlines degronons, co-degrading functional modules in the proteome. Communications Biology. 5: 445. PMID 35545699 DOI: 10.1038/s42003-022-03391-z  0.796
2020 Lazar T, Guharoy M, Vranken W, Rauscher S, Wodak SJ, Tompa P. Distance-Based Metrics for Comparing Conformational Ensembles of Intrinsically Disordered Proteins. Biophysical Journal. 118: 2952-2965. PMID 32502383 DOI: 10.1016/J.Bpj.2020.05.015  0.765
2019 Hatos A, Hajdu-Soltész B, Monzon AM, Palopoli N, Álvarez L, Aykac-Fas B, Bassot C, Benítez GI, Bevilacqua M, Chasapi A, Chemes L, Davey NE, Davidović R, Dunker AK, Elofsson A, ... ... Guharoy M, et al. DisProt: intrinsic protein disorder annotation in 2020. Nucleic Acids Research. PMID 31713636 DOI: 10.1093/Nar/Gkz975  0.702
2019 Macossay-Castillo M, Marvelli G, Guharoy M, Jain A, Kihara D, Tompa P, Wodak SJ. The Balancing Act of Intrinsically Disordered Proteins: Enabling Functional Diversity while Minimizing Promiscuity. Journal of Molecular Biology. PMID 30878482 DOI: 10.1016/J.Jmb.2019.03.008  0.808
2018 Lazar T, Guharoy M, Schad E, Tompa P. Unique Physicochemical Patterns of Residues in Protein-Protein Interfaces. Journal of Chemical Information and Modeling. PMID 30212197 DOI: 10.1021/acs.jcim.8b00270  0.738
2018 Guharoy M, Lazar T, Tompa P. Disordered substrates of the 20S proteasome link degradation with phase separation. Proteomics. e1800276. PMID 30070766 DOI: 10.1002/pmic.201800276  0.77
2017 Boeynaems S, Bogaert E, Kovacs D, Konijnenberg A, Timmerman E, Volkov A, Guharoy M, De Decker M, Jaspers T, Ryan VH, Janke AM, Baatsen P, Vercruysse T, Kolaitis RM, Daelemans D, et al. Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics. Molecular Cell. 65: 1044-1055.e5. PMID 28306503 DOI: 10.1016/J.Molcel.2017.02.013  0.608
2016 Braten O, Livneh I, Ziv T, Admon A, Kehat I, Caspi LH, Gonen H, Bercovich B, Godzik A, Jahandideh S, Jaroszewski L, Sommer T, Kwon YT, Guharoy M, Tompa P, et al. Numerous proteins with unique characteristics are degraded by the 26S proteasome following monoubiquitination. Proceedings of the National Academy of Sciences of the United States of America. PMID 27385826 DOI: 10.1073/Pnas.1608644113  0.675
2016 Guharoy M, Bhowmick P, Tompa P. Design Principles Involving Protein Disorder Facilitate Specific Substrate Selection and Degradation by the Ubiquitin-Proteasome System. The Journal of Biological Chemistry. 291: 6723-31. PMID 26851277 DOI: 10.1074/jbc.R115.692665  0.722
2016 Guharoy M, Bhowmick P, Sallam M, Tompa P. Tripartite degrons confer diversity and specificity on regulated protein degradation in the ubiquitin-proteasome system. Nature Communications. 7: 10239. PMID 26732515 DOI: 10.1038/ncomms10239  0.792
2015 Varadi M, Zsolyomi F, Guharoy M, Tompa P. Functional Advantages of Conserved Intrinsic Disorder in RNA-Binding Proteins. Plos One. 10: e0139731. PMID 26439842 DOI: 10.1371/journal.pone.0139731  0.727
2015 Borysik AJ, Kovacs D, Guharoy M, Tompa P. Ensemble Methods Enable a New Definition for the Solution to Gas-Phase Transfer of Intrinsically Disordered Proteins. Journal of the American Chemical Society. 137: 13807-17. PMID 26437245 DOI: 10.1021/jacs.5b06027  0.663
2015 Bhowmick P, Guharoy M, Tompa P. Bioinformatics Approaches for Predicting Disordered Protein Motifs. Advances in Experimental Medicine and Biology. 870: 291-318. PMID 26387106 DOI: 10.1007/978-3-319-20164-1_9  0.736
2015 Varadi M, Vranken W, Guharoy M, Tompa P. Computational approaches for inferring the functions of intrinsically disordered proteins. Frontiers in Molecular Biosciences. 2: 45. PMID 26301226 DOI: 10.3389/fmolb.2015.00045  0.771
2015 Guharoy M, Pauwels K, Tompa P. SnapShot: Intrinsic Structural Disorder. Cell. 161: 1230-1230.e1. PMID 26000490 DOI: 10.1016/j.cell.2015.05.024  0.771
2015 Varadi M, Guharoy M, Zsolyomi F, Tompa P. DisCons: a novel tool to quantify and classify evolutionary conservation of intrinsic protein disorder. Bmc Bioinformatics. 16: 153. PMID 25968230 DOI: 10.1186/s12859-015-0592-2  0.739
2013 Chakravarty D, Guharoy M, Robert CH, Chakrabarti P, Janin J. Reassessing buried surface areas in protein-protein complexes. Protein Science : a Publication of the Protein Society. 22: 1453-7. PMID 23934783 DOI: 10.1002/Pro.2330  0.44
2013 Guharoy M, Szabo B, Contreras Martos S, Kosol S, Tompa P. Intrinsic structural disorder in cytoskeletal proteins. Cytoskeleton (Hoboken, N.J.). 70: 550-71. PMID 23761374 DOI: 10.1002/cm.21118  0.7
2013 Bhowmick P, Pancsa R, Guharoy M, Tompa P. Functional diversity and structural disorder in the human ubiquitination pathway. Plos One. 8: e65443. PMID 23734257 DOI: 10.1371/journal.pone.0065443  0.671
2012 Dey S, Pal A, Guharoy M, Sonavane S, Chakrabarti P. Characterization and prediction of the binding site in DNA-binding proteins: improvement of accuracy by combining residue composition, evolutionary conservation and structural parameters. Nucleic Acids Research. 40: 7150-61. PMID 22641851 DOI: 10.1093/nar/gks405  0.313
2012 Dey S, Pal A, Guharoy M, Sonavane S, Chakrabarti P. Characterization and prediction of the binding site in DNA-binding proteins: improvement of accuracy by combining residue composition, evolutionary conservation and structural parameters. Nucleic Acids Research. 40: 7150-61. PMID 22641851 DOI: 10.1093/nar/gks405  0.313
2011 Fleishman SJ, Whitehead TA, Strauch EM, Corn JE, Qin S, Zhou HX, Mitchell JC, Demerdash ON, Takeda-Shitaka M, Terashi G, Moal IH, Li X, Bates PA, Zacharias M, Park H, ... ... Guharoy M, et al. Community-wide assessment of protein-interface modeling suggests improvements to design methodology. Journal of Molecular Biology. 414: 289-302. PMID 22001016 DOI: 10.1016/J.Jmb.2011.09.031  0.58
2011 Guharoy M, Pal A, Dasgupta M, Chakrabarti P. PRICE (PRotein Interface Conservation and Energetics): A server for the analysis of protein-protein interfaces Journal of Structural and Functional Genomics. 12: 33-41. PMID 21519818 DOI: 10.1007/s10969-011-9108-0  0.47
2010 Guharoy M, Janin J, Robert CH. Side-chain rotamer transitions at protein-protein interfaces. Proteins. 78: 3219-25. PMID 20737439 DOI: 10.1002/Prot.22821  0.402
2010 Guharoy M, Chakrabarti P. Conserved residue clusters at protein-protein interfaces and their use in binding site identification. Bmc Bioinformatics. 11: 286. PMID 20507585 DOI: 10.1186/1471-2105-11-286  0.472
2009 Guharoy M, Chakrabarti P. Empirical estimation of the energetic contribution of individual interface residues in structures of protein-protein complexes Journal of Computer-Aided Molecular Design. 23: 645-654. PMID 19479323 DOI: 10.1007/s10822-009-9282-3  0.345
2009 Biswas S, Guharoy M, Chakrabarti P. Dissection, residue conservation, and structural classification of protein-DNA interfaces. Proteins. 74: 643-54. PMID 18704949 DOI: 10.1002/prot.22180  0.43
2009 Biswas S, Guharoy M, Chakrabarti P. Dissection, residue conservation, and structural classification of protein-DNA interfaces. Proteins. 74: 643-54. PMID 18704949 DOI: 10.1002/prot.22180  0.43
2008 Biswas S, Guharoy M, Chakrabarti P. Structural segments and residue propensities in protein-RNA interfaces: comparison with protein-protein and protein-DNA complexes. Bioinformation. 2: 422-7. PMID 18841236 DOI: 10.6026/97320630002422  0.435
2008 Biswas S, Guharoy M, Chakrabarti P. Structural segments and residue propensities in protein-RNA interfaces: comparison with protein-protein and protein-DNA complexes. Bioinformation. 2: 422-7. PMID 18841236 DOI: 10.6026/97320630002422  0.435
2007 Guharoy M, Chakrabarti P. Secondary structure based analysis and classification of biological interfaces: Identification of binding motifs in protein-protein interactions Bioinformatics. 23: 1909-1918. PMID 17510165 DOI: 10.1093/bioinformatics/btm274  0.45
2005 Guharoy M, Chakrabarti P. Conservation and relative importance of residues across protein-protein interfaces Proceedings of the National Academy of Sciences of the United States of America. 102: 15447-15452. PMID 16221766 DOI: 10.1073/pnas.0505425102  0.363
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