Jonathon A. Ditlev - Publications

Affiliations: 
Hospital for Sick Children Research Institute, Toronto, Ontario, Canada 

23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Wang HY, Chan SH, Dey S, Castello-Serrano I, Rosen MK, Ditlev JA, Levental KR, Levental I. Coupling of protein condensates to ordered lipid domains determines functional membrane organization. Science Advances. 9: eadf6205. PMID 37126554 DOI: 10.1126/sciadv.adf6205  0.592
2021 Zhemkov V, Ditlev JA, Lee WR, Wilson M, Liou J, Rosen MK, Bezprozvanny I. The role of sigma 1 receptor in organization of endoplasmic reticulum signaling microdomains. Elife. 10. PMID 33973848 DOI: 10.7554/eLife.65192  0.606
2021 Ditlev JA. Membrane-associated phase separation: organization and function emerge from a two-dimensional milieu. Journal of Molecular Cell Biology. PMID 33532844 DOI: 10.1093/jmcb/mjab010  0.339
2021 Jaqaman K, Ditlev JA. Biomolecular condensates in membrane receptor signaling. Current Opinion in Cell Biology. 69: 48-54. PMID 33461072 DOI: 10.1016/j.ceb.2020.12.006  0.512
2020 Zhang R, Lee DM, Jimah JR, Gerassimov N, Yang C, Kim S, Luvsanjav D, Winkelman J, Mettlen M, Abrams ME, Kalia R, Keene P, Pandey P, Ravaux B, Kim JH, ... Ditlev JA, et al. Dynamin regulates the dynamics and mechanical strength of the actin cytoskeleton as a multifilament actin-bundling protein. Nature Cell Biology. PMID 32451441 DOI: 10.1038/S41556-020-0519-7  0.522
2020 Wang H, Diaz-Rohrer B, Levental KR, Ditlev JA, Rosen MK, Levental I. Coupling between Cytoplasmic Protein Phase Separation and Cholesterol-Rich Domains in the Plasma Membrane Facilitates T Cell Activation Biophysical Journal. 118: 322a. DOI: 10.1016/J.Bpj.2019.11.1811  0.572
2019 Ditlev JA, Vega AR, Köster DV, Su X, Tani T, Lakoduk AM, Vale RD, Mayor S, Jaqaman K, Rosen MK. A composition-dependent molecular clutch between T cell signaling condensates and actin. Elife. 8. PMID 31268421 DOI: 10.7554/Elife.42695  0.571
2019 Case LB, Ditlev JA, Rosen MK. Regulation of Transmembrane Signaling by Phase Separation. Annual Review of Biophysics. PMID 30951647 DOI: 10.1146/Annurev-Biophys-052118-115534  0.697
2019 Case LB, Zhang X, Ditlev JA, Rosen MK. Stoichiometry controls activity of phase-separated clusters of actin signaling proteins. Science (New York, N.Y.). 363: 1093-1097. PMID 30846599 DOI: 10.1126/Science.Aau6313  0.716
2019 Ditlev JA, Vega AR, Köster DV, Su X, Tani T, Lakoduk AM, Vale RD, Mayor S, Jaqaman K, Rosen MK. Author response: A composition-dependent molecular clutch between T cell signaling condensates and actin Elife. DOI: 10.7554/Elife.42695.061  0.552
2019 Kim J, Ditlev J, Rosen MK. Abstract B169: Engineering phase separation of multivalent signaling proteins through the solubility of folded protein domains Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-B169  0.65
2018 Ditlev JA, Case LB, Rosen MK. Who's in and Who's Out-Compositional Control of Biomolecular Condensates. Journal of Molecular Biology. PMID 30099028 DOI: 10.1016/J.Jmb.2018.08.003  0.685
2018 Vega A, Ditlev J, Koster D, Su X, Vale R, Mayor S, Rosen MK, Jaqaman K. Differential LAT Microcluster Composition and ACTIN-Dependent Movement at the Immunological Synapse Center Biophysical Journal. 114: 201a. DOI: 10.1016/J.Bpj.2017.11.1123  0.453
2017 Huang WYC, Ditlev JA, Chiang HK, Rosen MK, Groves JT. Allosteric Modulation of Grb2 Recruitment to the Intrinsically Disordered Scaffold Protein, LAT, by Remote Site Phosphorylation. Journal of the American Chemical Society. 139: 18009-18015. PMID 29182244 DOI: 10.1021/Jacs.7B09387  0.583
2017 Su X, Ditlev JA, Rosen MK, Vale RD. Reconstitution of TCR Signaling Using Supported Lipid Bilayers. Methods in Molecular Biology (Clifton, N.J.). 1584: 65-76. PMID 28255696 DOI: 10.1007/978-1-4939-6881-7_5  0.62
2016 Su X, Ditlev JA, Hui E, Xing W, Banjade S, Okrut J, King DS, Taunton J, Rosen MK, Vale RD. Phase separation of signaling molecules promotes T cell receptor signal transduction. Science (New York, N.Y.). PMID 27056844 DOI: 10.1126/Science.Aad9964  0.675
2016 Su X, Ditlev J, Hui E, Banjade S, Okrut J, Taunton J, Rosen M, Vale R. Abstract A087: Phase separation of signaling molecules promotes T cell receptor signal transduction Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-A087  0.517
2016 Su X, Ditlev J, Hui E, Rosen M, Vale R. Abstract B101: Mechanism of T cell activation by phase separation Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-B101  0.668
2016 Vega AR, Ditlev JA, Rosen MK, Jaqaman K. Quantitative Analysis of Cortical Actin-Membrane Microcluster Interactions Biophysical Journal. 110: 330a. DOI: 10.1016/J.Bpj.2015.11.1775  0.587
2013 Borinskaya S, Ditlev J, Loew L, Mayer B. Clusters of Arp2/3 Activators Mimic Pathogenic Actin Comets and Pedestals Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.3369  0.398
2012 Ditlev JA, Michalski PJ, Huber G, Rivera GM, Mohler WA, Loew LM, Mayer BJ. Stoichiometry of Nck-dependent actin polymerization in living cells. The Journal of Cell Biology. 197: 643-58. PMID 22613834 DOI: 10.1083/Jcb.201111113  0.331
2011 Ditlev JA, Mayer BJ, Loew LM. Nck Function in Tyrosine Kinase Signaling to the Actin Cytoskeleton Biophysical Journal. 100: 596a-597a. DOI: 10.1016/J.Bpj.2010.12.3437  0.35
2011 Borinskaya S, Ditlev JA, Loew LM, Mayer BJ. Investigating Function of Nck Adaptor in Tyrosine Kinase Signaling to the Actin Cytoskeleton Biophysical Journal. 100: 5-6. DOI: 10.1016/J.Bpj.2010.12.3436  0.395
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