Ben G. Wen, Ph.D.
Affiliations: | 2002 | University of California, San Diego, La Jolla, CA |
Area:
Immunology, Cell Biology, Molecular BiologyGoogle:
"Ben Wen"Parents
Sign in to add mentor| Stephen M Hedrick | grad student | 2002 | UCSD | |
| (Studies on the molecular mechanisms of thymocyte negative selection and the role of murine DRAK2 in T cell activation.) | ||||
BETA: Related publications
See more...
Publications
|
You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect. |
| Velcicky J, Mathison CJN, Nikulin V, et al. (2019) Discovery of Orally Active Hydroxyethylamine Based SPPL2a Inhibitors. Acs Medicinal Chemistry Letters. 10: 887-892 |
| Velcicky J, Bodendorf U, Rigollier P, et al. (2018) Discovery of the First Potent, Selective, and Orally Bioavailable Signal Peptide Peptidase-Like 2a (SPPL2a) Inhibitor Displaying Pronounced Immunomodulatory Effects In Vivo. Journal of Medicinal Chemistry |
| Miller AT, Dahlberg C, Sandberg ML, et al. (2015) Inhibition of the Inositol Kinase Itpkb Augments Calcium Signaling in Lymphocytes and Reveals a Novel Strategy to Treat Autoimmune Disease. Plos One. 10: e0131071 |
| Hannedouche S, Zhang J, Yi T, et al. (2011) Oxysterols direct immune cell migration via EBI2. Nature. 475: 524-7 |
| McGargill MA, Choy C, Wen BG, et al. (2008) Drak2 regulates the survival of activated T cells and is required for organ-specific autoimmune disease. Journal of Immunology (Baltimore, Md. : 1950). 181: 7593-605 |
| Friedrich ML, Wen BG, Bain G, et al. (2005) DRAK2, a lymphoid-enriched DAP kinase, regulates the TCR activation threshold during thymocyte selection. International Immunology. 17: 1379-90 |
| McGargill MA, Wen BG, Walsh CM, et al. (2004) A deficiency in Drak2 results in a T cell hypersensitivity and an unexpected resistance to autoimmunity. Immunity. 21: 781-91 |
| Wen BG, Pletcher MT, Warashina M, et al. (2004) Inositol (1,4,5) trisphosphate 3 kinase B controls positive selection of T cells and modulates Erk activity. Proceedings of the National Academy of Sciences of the United States of America. 101: 5604-9 |
| Walsh CM, Wen BG, Chinnaiyan AM, et al. (1998) A role for FADD in T cell activation and development Immunity. 8: 439-449 |